Amino acid dipepetide frequency for Papaya cytorhabdovirus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.761AlaAla: 2.761 ± 0.823
0.251AlaCys: 0.251 ± 0.357
3.263AlaAsp: 3.263 ± 1.11
4.267AlaGlu: 4.267 ± 0.889
2.259AlaPhe: 2.259 ± 0.532
2.51AlaGly: 2.51 ± 0.959
1.004AlaHis: 1.004 ± 0.929
3.514AlaIle: 3.514 ± 0.489
3.012AlaLys: 3.012 ± 1.376
3.514AlaLeu: 3.514 ± 0.848
1.506AlaMet: 1.506 ± 0.658
2.51AlaAsn: 2.51 ± 0.64
1.757AlaPro: 1.757 ± 1.266
1.506AlaGln: 1.506 ± 0.468
1.757AlaArg: 1.757 ± 0.551
4.518AlaSer: 4.518 ± 0.997
2.51AlaThr: 2.51 ± 0.727
4.016AlaVal: 4.016 ± 0.95
0.753AlaTrp: 0.753 ± 0.692
1.506AlaTyr: 1.506 ± 0.484
0.0AlaXaa: 0.0 ± 0.0
Cys
1.506CysAla: 1.506 ± 0.448
0.502CysCys: 0.502 ± 0.48
1.004CysAsp: 1.004 ± 0.39
0.753CysGlu: 0.753 ± 0.298
1.255CysPhe: 1.255 ± 0.374
1.004CysGly: 1.004 ± 0.838
0.753CysHis: 0.753 ± 0.345
1.004CysIle: 1.004 ± 0.35
2.259CysLys: 2.259 ± 1.078
2.008CysLeu: 2.008 ± 1.188
0.251CysMet: 0.251 ± 0.3
0.251CysAsn: 0.251 ± 0.145
0.753CysPro: 0.753 ± 0.378
0.0CysGln: 0.0 ± 0.0
0.753CysArg: 0.753 ± 0.298
1.004CysSer: 1.004 ± 0.62
0.502CysThr: 0.502 ± 0.291
1.757CysVal: 1.757 ± 1.077
0.251CysTrp: 0.251 ± 0.145
0.502CysTyr: 0.502 ± 0.587
0.0CysXaa: 0.0 ± 0.0
Asp
2.51AspAla: 2.51 ± 1.076
0.251AspCys: 0.251 ± 0.145
4.267AspAsp: 4.267 ± 1.063
4.769AspGlu: 4.769 ± 1.333
2.008AspPhe: 2.008 ± 0.342
3.514AspGly: 3.514 ± 0.642
0.753AspHis: 0.753 ± 0.317
4.769AspIle: 4.769 ± 1.266
4.016AspLys: 4.016 ± 0.857
4.016AspLeu: 4.016 ± 0.874
1.506AspMet: 1.506 ± 0.851
2.761AspAsn: 2.761 ± 0.43
3.514AspPro: 3.514 ± 1.35
2.51AspGln: 2.51 ± 0.557
2.51AspArg: 2.51 ± 0.444
4.518AspSer: 4.518 ± 0.637
2.761AspThr: 2.761 ± 0.966
2.008AspVal: 2.008 ± 0.467
0.0AspTrp: 0.0 ± 0.0
1.506AspTyr: 1.506 ± 0.513
0.0AspXaa: 0.0 ± 0.0
Glu
3.514GluAla: 3.514 ± 0.719
1.004GluCys: 1.004 ± 0.523
4.267GluAsp: 4.267 ± 1.731
7.028GluGlu: 7.028 ± 3.972
2.008GluPhe: 2.008 ± 0.835
5.02GluGly: 5.02 ± 1.361
1.506GluHis: 1.506 ± 0.657
6.777GluIle: 6.777 ± 1.369
7.279GluLys: 7.279 ± 3.879
8.534GluLeu: 8.534 ± 0.72
1.506GluMet: 1.506 ± 1.063
2.51GluAsn: 2.51 ± 0.865
2.51GluPro: 2.51 ± 0.657
1.506GluGln: 1.506 ± 0.436
3.765GluArg: 3.765 ± 1.086
3.514GluSer: 3.514 ± 0.846
2.259GluThr: 2.259 ± 0.374
5.522GluVal: 5.522 ± 2.675
0.753GluTrp: 0.753 ± 0.298
1.255GluTyr: 1.255 ± 0.831
0.0GluXaa: 0.0 ± 0.0
Phe
2.761PheAla: 2.761 ± 1.284
0.753PheCys: 0.753 ± 0.938
1.004PheAsp: 1.004 ± 0.39
2.259PheGlu: 2.259 ± 0.631
3.514PhePhe: 3.514 ± 1.1
4.518PheGly: 4.518 ± 1.314
1.255PheHis: 1.255 ± 0.727
1.004PheIle: 1.004 ± 0.582
3.012PheLys: 3.012 ± 1.108
4.267PheLeu: 4.267 ± 1.092
1.004PheMet: 1.004 ± 0.483
2.008PheAsn: 2.008 ± 0.645
2.51PhePro: 2.51 ± 0.999
2.008PheGln: 2.008 ± 0.91
2.008PheArg: 2.008 ± 0.78
5.773PheSer: 5.773 ± 1.163
3.012PheThr: 3.012 ± 0.896
1.757PheVal: 1.757 ± 0.683
1.004PheTrp: 1.004 ± 0.467
2.259PheTyr: 2.259 ± 0.983
0.0PheXaa: 0.0 ± 0.0
Gly
1.757GlyAla: 1.757 ± 0.635
0.251GlyCys: 0.251 ± 0.446
3.514GlyAsp: 3.514 ± 1.153
3.514GlyGlu: 3.514 ± 0.526
2.259GlyPhe: 2.259 ± 0.757
2.51GlyGly: 2.51 ± 0.775
2.008GlyHis: 2.008 ± 0.639
4.016GlyIle: 4.016 ± 1.227
4.016GlyLys: 4.016 ± 1.293
5.522GlyLeu: 5.522 ± 1.266
2.259GlyMet: 2.259 ± 0.902
1.757GlyAsn: 1.757 ± 0.707
1.757GlyPro: 1.757 ± 1.332
1.004GlyGln: 1.004 ± 0.293
3.765GlyArg: 3.765 ± 0.765
4.016GlySer: 4.016 ± 1.072
2.51GlyThr: 2.51 ± 0.329
4.267GlyVal: 4.267 ± 0.768
1.004GlyTrp: 1.004 ± 0.582
1.506GlyTyr: 1.506 ± 0.684
0.0GlyXaa: 0.0 ± 0.0
His
0.502HisAla: 0.502 ± 0.434
0.251HisCys: 0.251 ± 0.406
1.255HisAsp: 1.255 ± 0.55
1.255HisGlu: 1.255 ± 0.374
1.757HisPhe: 1.757 ± 0.544
0.753HisGly: 0.753 ± 0.35
0.753HisHis: 0.753 ± 0.298
1.255HisIle: 1.255 ± 0.542
1.004HisLys: 1.004 ± 0.35
2.259HisLeu: 2.259 ± 0.575
0.251HisMet: 0.251 ± 0.145
1.004HisAsn: 1.004 ± 0.428
1.004HisPro: 1.004 ± 0.428
0.753HisGln: 0.753 ± 0.501
0.753HisArg: 0.753 ± 0.598
1.004HisSer: 1.004 ± 0.39
0.502HisThr: 0.502 ± 0.287
1.757HisVal: 1.757 ± 0.441
0.0HisTrp: 0.0 ± 0.0
1.004HisTyr: 1.004 ± 0.303
0.0HisXaa: 0.0 ± 0.0
Ile
3.514IleAla: 3.514 ± 1.262
1.255IleCys: 1.255 ± 0.501
4.267IleAsp: 4.267 ± 0.763
4.518IleGlu: 4.518 ± 1.343
4.518IlePhe: 4.518 ± 1.318
3.012IleGly: 3.012 ± 1.094
0.251IleHis: 0.251 ± 0.145
3.012IleIle: 3.012 ± 0.604
4.518IleLys: 4.518 ± 1.213
4.267IleLeu: 4.267 ± 1.056
1.757IleMet: 1.757 ± 0.543
2.259IleAsn: 2.259 ± 0.797
3.765IlePro: 3.765 ± 0.798
2.008IleGln: 2.008 ± 0.613
4.016IleArg: 4.016 ± 1.675
5.773IleSer: 5.773 ± 1.785
3.514IleThr: 3.514 ± 1.078
4.518IleVal: 4.518 ± 1.987
0.753IleTrp: 0.753 ± 0.436
2.008IleTyr: 2.008 ± 1.301
0.0IleXaa: 0.0 ± 0.0
Lys
1.757LysAla: 1.757 ± 0.404
2.008LysCys: 2.008 ± 0.679
4.267LysAsp: 4.267 ± 1.356
8.785LysGlu: 8.785 ± 2.692
2.761LysPhe: 2.761 ± 1.088
7.53LysGly: 7.53 ± 1.4
0.502LysHis: 0.502 ± 0.322
3.765LysIle: 3.765 ± 1.083
7.781LysLys: 7.781 ± 2.72
5.773LysLeu: 5.773 ± 0.655
3.012LysMet: 3.012 ± 0.975
3.012LysAsn: 3.012 ± 0.412
2.51LysPro: 2.51 ± 1.342
1.255LysGln: 1.255 ± 0.327
3.514LysArg: 3.514 ± 1.834
5.522LysSer: 5.522 ± 1.463
6.275LysThr: 6.275 ± 1.68
6.275LysVal: 6.275 ± 1.923
1.255LysTrp: 1.255 ± 0.727
2.008LysTyr: 2.008 ± 1.108
0.0LysXaa: 0.0 ± 0.0
Leu
5.522LeuAla: 5.522 ± 0.827
3.012LeuCys: 3.012 ± 0.602
4.016LeuAsp: 4.016 ± 1.38
6.526LeuGlu: 6.526 ± 1.509
5.271LeuPhe: 5.271 ± 1.451
4.518LeuGly: 4.518 ± 1.225
1.757LeuHis: 1.757 ± 0.632
5.522LeuIle: 5.522 ± 0.779
6.275LeuLys: 6.275 ± 1.356
7.53LeuLeu: 7.53 ± 1.677
4.769LeuMet: 4.769 ± 1.056
3.012LeuAsn: 3.012 ± 0.75
4.518LeuPro: 4.518 ± 1.116
2.51LeuGln: 2.51 ± 0.444
4.518LeuArg: 4.518 ± 1.765
8.785LeuSer: 8.785 ± 1.366
6.526LeuThr: 6.526 ± 1.773
5.522LeuVal: 5.522 ± 1.137
0.753LeuTrp: 0.753 ± 0.398
1.757LeuTyr: 1.757 ± 0.679
0.0LeuXaa: 0.0 ± 0.0
Met
1.757MetAla: 1.757 ± 0.758
0.502MetCys: 0.502 ± 0.48
2.008MetAsp: 2.008 ± 0.73
2.259MetGlu: 2.259 ± 0.463
0.753MetPhe: 0.753 ± 0.436
1.506MetGly: 1.506 ± 0.474
0.502MetHis: 0.502 ± 0.715
2.008MetIle: 2.008 ± 0.643
1.757MetLys: 1.757 ± 1.056
3.514MetLeu: 3.514 ± 1.543
1.255MetMet: 1.255 ± 0.641
0.753MetAsn: 0.753 ± 0.396
0.502MetPro: 0.502 ± 0.322
1.004MetGln: 1.004 ± 0.608
1.506MetArg: 1.506 ± 0.675
3.012MetSer: 3.012 ± 1.306
2.51MetThr: 2.51 ± 0.713
2.008MetVal: 2.008 ± 0.856
0.502MetTrp: 0.502 ± 0.261
1.004MetTyr: 1.004 ± 0.641
0.0MetXaa: 0.0 ± 0.0
Asn
2.008AsnAla: 2.008 ± 0.572
1.255AsnCys: 1.255 ± 0.374
1.757AsnAsp: 1.757 ± 0.768
2.259AsnGlu: 2.259 ± 0.635
2.259AsnPhe: 2.259 ± 0.777
0.753AsnGly: 0.753 ± 0.544
1.004AsnHis: 1.004 ± 0.423
2.51AsnIle: 2.51 ± 0.631
2.259AsnLys: 2.259 ± 0.902
3.765AsnLeu: 3.765 ± 0.8
1.004AsnMet: 1.004 ± 0.508
1.255AsnAsn: 1.255 ± 0.722
2.259AsnPro: 2.259 ± 0.615
1.004AsnGln: 1.004 ± 0.293
1.004AsnArg: 1.004 ± 0.39
5.02AsnSer: 5.02 ± 0.604
1.255AsnThr: 1.255 ± 0.417
1.255AsnVal: 1.255 ± 0.513
0.251AsnTrp: 0.251 ± 0.145
2.008AsnTyr: 2.008 ± 0.639
0.0AsnXaa: 0.0 ± 0.0
Pro
2.008ProAla: 2.008 ± 0.572
0.502ProCys: 0.502 ± 0.291
1.255ProAsp: 1.255 ± 0.321
2.51ProGlu: 2.51 ± 0.633
2.259ProPhe: 2.259 ± 0.536
2.008ProGly: 2.008 ± 0.745
1.004ProHis: 1.004 ± 0.491
3.514ProIle: 3.514 ± 1.434
4.769ProLys: 4.769 ± 1.292
3.012ProLeu: 3.012 ± 0.514
0.251ProMet: 0.251 ± 0.645
0.251ProAsn: 0.251 ± 0.145
4.518ProPro: 4.518 ± 1.282
1.255ProGln: 1.255 ± 0.982
2.51ProArg: 2.51 ± 0.692
4.016ProSer: 4.016 ± 0.668
3.012ProThr: 3.012 ± 0.93
3.263ProVal: 3.263 ± 1.489
0.502ProTrp: 0.502 ± 0.322
3.012ProTyr: 3.012 ± 0.641
0.0ProXaa: 0.0 ± 0.0
Gln
1.506GlnAla: 1.506 ± 0.657
0.753GlnCys: 0.753 ± 0.298
3.514GlnAsp: 3.514 ± 0.497
2.761GlnGlu: 2.761 ± 0.641
1.004GlnPhe: 1.004 ± 0.35
1.506GlnGly: 1.506 ± 0.471
0.502GlnHis: 0.502 ± 0.577
1.255GlnIle: 1.255 ± 0.542
2.761GlnLys: 2.761 ± 0.86
4.016GlnLeu: 4.016 ± 1.348
0.251GlnMet: 0.251 ± 0.357
0.0GlnAsn: 0.0 ± 0.0
0.251GlnPro: 0.251 ± 0.3
0.753GlnGln: 0.753 ± 0.491
0.753GlnArg: 0.753 ± 0.317
2.008GlnSer: 2.008 ± 0.922
1.757GlnThr: 1.757 ± 1.18
2.259GlnVal: 2.259 ± 0.473
0.251GlnTrp: 0.251 ± 0.327
1.004GlnTyr: 1.004 ± 0.582
0.0GlnXaa: 0.0 ± 0.0
Arg
2.761ArgAla: 2.761 ± 0.552
0.502ArgCys: 0.502 ± 0.48
3.765ArgAsp: 3.765 ± 1.369
2.259ArgGlu: 2.259 ± 1.302
2.008ArgPhe: 2.008 ± 0.63
2.259ArgGly: 2.259 ± 0.993
1.004ArgHis: 1.004 ± 0.303
3.514ArgIle: 3.514 ± 0.955
3.263ArgLys: 3.263 ± 0.935
3.765ArgLeu: 3.765 ± 1.316
2.259ArgMet: 2.259 ± 0.603
1.506ArgAsn: 1.506 ± 0.468
2.008ArgPro: 2.008 ± 0.476
1.255ArgGln: 1.255 ± 0.321
2.008ArgArg: 2.008 ± 0.496
4.267ArgSer: 4.267 ± 1.181
3.012ArgThr: 3.012 ± 1.187
2.51ArgVal: 2.51 ± 0.598
0.251ArgTrp: 0.251 ± 0.145
1.757ArgTyr: 1.757 ± 0.632
0.0ArgXaa: 0.0 ± 0.0
Ser
4.016SerAla: 4.016 ± 1.426
1.757SerCys: 1.757 ± 0.857
3.263SerAsp: 3.263 ± 1.546
7.028SerGlu: 7.028 ± 1.678
3.514SerPhe: 3.514 ± 1.187
4.016SerGly: 4.016 ± 1.206
2.259SerHis: 2.259 ± 1.33
5.773SerIle: 5.773 ± 1.111
5.522SerLys: 5.522 ± 0.719
10.291SerLeu: 10.291 ± 1.83
3.263SerMet: 3.263 ± 0.591
3.263SerAsn: 3.263 ± 0.985
3.765SerPro: 3.765 ± 0.882
2.259SerGln: 2.259 ± 0.536
3.012SerArg: 3.012 ± 0.945
12.048SerSer: 12.048 ± 3.244
5.522SerThr: 5.522 ± 0.981
5.02SerVal: 5.02 ± 1.382
1.255SerTrp: 1.255 ± 0.507
5.02SerTyr: 5.02 ± 1.55
0.0SerXaa: 0.0 ± 0.0
Thr
2.259ThrAla: 2.259 ± 1.25
1.004ThrCys: 1.004 ± 0.608
2.51ThrAsp: 2.51 ± 0.892
3.514ThrGlu: 3.514 ± 0.948
3.012ThrPhe: 3.012 ± 0.915
1.506ThrGly: 1.506 ± 0.657
1.004ThrHis: 1.004 ± 0.428
2.51ThrIle: 2.51 ± 0.779
4.769ThrLys: 4.769 ± 0.69
5.522ThrLeu: 5.522 ± 1.144
0.753ThrMet: 0.753 ± 0.317
1.757ThrAsn: 1.757 ± 0.544
3.514ThrPro: 3.514 ± 0.828
1.757ThrGln: 1.757 ± 0.514
2.761ThrArg: 2.761 ± 0.813
5.773ThrSer: 5.773 ± 1.048
3.012ThrThr: 3.012 ± 0.657
5.522ThrVal: 5.522 ± 3.631
1.757ThrTrp: 1.757 ± 0.719
2.008ThrTyr: 2.008 ± 0.844
0.0ThrXaa: 0.0 ± 0.0
Val
2.51ValAla: 2.51 ± 0.744
1.506ValCys: 1.506 ± 0.382
2.51ValAsp: 2.51 ± 0.64
3.765ValGlu: 3.765 ± 1.913
4.267ValPhe: 4.267 ± 1.168
2.259ValGly: 2.259 ± 0.947
0.251ValHis: 0.251 ± 0.327
4.518ValIle: 4.518 ± 1.421
8.283ValLys: 8.283 ± 1.77
5.773ValLeu: 5.773 ± 1.003
2.008ValMet: 2.008 ± 0.755
3.012ValAsn: 3.012 ± 0.763
3.012ValPro: 3.012 ± 0.657
2.51ValGln: 2.51 ± 0.581
3.765ValArg: 3.765 ± 0.926
7.028ValSer: 7.028 ± 2.362
3.765ValThr: 3.765 ± 1.165
5.773ValVal: 5.773 ± 1.046
0.753ValTrp: 0.753 ± 0.436
1.255ValTyr: 1.255 ± 0.535
0.0ValXaa: 0.0 ± 0.0
Trp
1.004TrpAla: 1.004 ± 0.384
0.0TrpCys: 0.0 ± 0.0
1.506TrpAsp: 1.506 ± 0.636
0.753TrpGlu: 0.753 ± 0.298
0.502TrpPhe: 0.502 ± 0.291
1.255TrpGly: 1.255 ± 0.498
0.251TrpHis: 0.251 ± 0.357
0.753TrpIle: 0.753 ± 0.436
0.502TrpLys: 0.502 ± 0.291
0.753TrpLeu: 0.753 ± 0.398
0.251TrpMet: 0.251 ± 0.145
1.255TrpAsn: 1.255 ± 0.55
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.502TrpArg: 0.502 ± 0.291
1.255TrpSer: 1.255 ± 0.542
0.753TrpThr: 0.753 ± 0.35
1.255TrpVal: 1.255 ± 0.374
0.251TrpTrp: 0.251 ± 0.3
0.251TrpTyr: 0.251 ± 0.145
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.761TyrAla: 2.761 ± 1.502
0.753TyrCys: 0.753 ± 0.544
1.255TyrAsp: 1.255 ± 0.542
1.255TyrGlu: 1.255 ± 0.506
0.502TyrPhe: 0.502 ± 0.291
1.255TyrGly: 1.255 ± 0.535
0.753TyrHis: 0.753 ± 0.436
2.51TyrIle: 2.51 ± 0.989
2.51TyrLys: 2.51 ± 0.963
4.518TyrLeu: 4.518 ± 0.949
1.255TyrMet: 1.255 ± 1.05
2.008TyrAsn: 2.008 ± 1.046
1.255TyrPro: 1.255 ± 0.535
2.008TyrGln: 2.008 ± 0.676
0.753TyrArg: 0.753 ± 0.398
3.012TyrSer: 3.012 ± 0.822
1.255TyrThr: 1.255 ± 1.234
2.259TyrVal: 2.259 ± 0.465
0.753TyrTrp: 0.753 ± 0.415
1.757TyrTyr: 1.757 ± 0.727
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 8 proteins (3985 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski