Amino acid dipepetide frequency for Corynebacterium tapiri

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	15.283AlaAla: 15.283 ± 0.242	1.007AlaCys: 1.007 ± 0.044	6.743AlaAsp: 6.743 ± 0.102	8.094AlaGlu: 8.094 ± 0.13	3.655AlaPhe: 3.655 ± 0.075	10.468AlaGly: 10.468 ± 0.148	2.711AlaHis: 2.711 ± 0.066	5.505AlaIle: 5.505 ± 0.096	3.343AlaLys: 3.343 ± 0.09	12.189AlaLeu: 12.189 ± 0.173	2.606AlaMet: 2.606 ± 0.056	2.811AlaAsn: 2.811 ± 0.071	5.449AlaPro: 5.449 ± 0.127	5.084AlaGln: 5.084 ± 0.093	7.637AlaArg: 7.637 ± 0.135	6.429AlaSer: 6.429 ± 0.115	6.56AlaThr: 6.56 ± 0.098	9.649AlaVal: 9.649 ± 0.127	1.515AlaTrp: 1.515 ± 0.058	2.311AlaTyr: 2.311 ± 0.052	0.0AlaXaa: 0.0 ± 0.0
Cys	0.947CysAla: 0.947 ± 0.042	0.051CysCys: 0.051 ± 0.01	0.39CysAsp: 0.39 ± 0.023	0.407CysGlu: 0.407 ± 0.024	0.225CysPhe: 0.225 ± 0.017	0.742CysGly: 0.742 ± 0.036	0.181CysHis: 0.181 ± 0.019	0.307CysIle: 0.307 ± 0.023	0.127CysLys: 0.127 ± 0.015	0.613CysLeu: 0.613 ± 0.031	0.096CysMet: 0.096 ± 0.011	0.147CysAsn: 0.147 ± 0.015	0.422CysPro: 0.422 ± 0.034	0.25CysGln: 0.25 ± 0.02	0.355CysArg: 0.355 ± 0.024	0.521CysSer: 0.521 ± 0.029	0.444CysThr: 0.444 ± 0.027	0.617CysVal: 0.617 ± 0.035	0.085CysTrp: 0.085 ± 0.01	0.131CysTyr: 0.131 ± 0.014	0.0CysXaa: 0.0 ± 0.0
Asp	6.875AspAla: 6.875 ± 0.093	0.397AspCys: 0.397 ± 0.029	3.371AspAsp: 3.371 ± 0.092	4.332AspGlu: 4.332 ± 0.098	2.017AspPhe: 2.017 ± 0.061	4.862AspGly: 4.862 ± 0.102	1.4AspHis: 1.4 ± 0.042	2.708AspIle: 2.708 ± 0.064	1.873AspLys: 1.873 ± 0.056	5.595AspLeu: 5.595 ± 0.099	1.128AspMet: 1.128 ± 0.047	1.633AspAsn: 1.633 ± 0.048	3.797AspPro: 3.797 ± 0.081	1.936AspGln: 1.936 ± 0.053	3.395AspArg: 3.395 ± 0.073	3.283AspSer: 3.283 ± 0.087	2.987AspThr: 2.987 ± 0.087	5.197AspVal: 5.197 ± 0.1	0.753AspTrp: 0.753 ± 0.038	1.54AspTyr: 1.54 ± 0.056	0.0AspXaa: 0.0 ± 0.0
Glu	7.159GluAla: 7.159 ± 0.126	0.413GluCys: 0.413 ± 0.028	3.658GluAsp: 3.658 ± 0.082	4.13GluGlu: 4.13 ± 0.097	2.03GluPhe: 2.03 ± 0.053	4.474GluGly: 4.474 ± 0.097	1.759GluHis: 1.759 ± 0.052	3.211GluIle: 3.211 ± 0.073	2.41GluLys: 2.41 ± 0.062	7.018GluLeu: 7.018 ± 0.123	1.231GluMet: 1.231 ± 0.041	1.791GluAsn: 1.791 ± 0.062	2.919GluPro: 2.919 ± 0.071	2.79GluGln: 2.79 ± 0.07	4.732GluArg: 4.732 ± 0.103	3.411GluSer: 3.411 ± 0.078	3.131GluThr: 3.131 ± 0.07	5.019GluVal: 5.019 ± 0.092	0.813GluTrp: 0.813 ± 0.036	1.372GluTyr: 1.372 ± 0.039	0.0GluXaa: 0.0 ± 0.0
Phe	3.886PheAla: 3.886 ± 0.084	0.242PheCys: 0.242 ± 0.02	2.318PheAsp: 2.318 ± 0.06	1.8PheGlu: 1.8 ± 0.053	1.156PhePhe: 1.156 ± 0.047	3.436PheGly: 3.436 ± 0.076	0.711PheHis: 0.711 ± 0.035	1.495PheIle: 1.495 ± 0.046	0.725PheLys: 0.725 ± 0.033	2.934PheLeu: 2.934 ± 0.065	0.559PheMet: 0.559 ± 0.03	0.956PheAsn: 0.956 ± 0.041	1.375PhePro: 1.375 ± 0.045	0.842PheGln: 0.842 ± 0.036	1.65PheArg: 1.65 ± 0.048	2.21PheSer: 2.21 ± 0.058	2.187PheThr: 2.187 ± 0.069	2.638PheVal: 2.638 ± 0.072	0.436PheTrp: 0.436 ± 0.028	0.813PheTyr: 0.813 ± 0.037	0.0PheXaa: 0.0 ± 0.0
Gly	8.872GlyAla: 8.872 ± 0.125	0.666GlyCys: 0.666 ± 0.036	4.452GlyAsp: 4.452 ± 0.093	5.286GlyGlu: 5.286 ± 0.088	3.112GlyPhe: 3.112 ± 0.066	6.667GlyGly: 6.667 ± 0.142	1.987GlyHis: 1.987 ± 0.061	4.438GlyIle: 4.438 ± 0.098	2.922GlyLys: 2.922 ± 0.071	8.284GlyLeu: 8.284 ± 0.119	2.155GlyMet: 2.155 ± 0.064	2.333GlyAsn: 2.333 ± 0.066	3.416GlyPro: 3.416 ± 0.07	3.121GlyGln: 3.121 ± 0.068	5.026GlyArg: 5.026 ± 0.097	5.109GlySer: 5.109 ± 0.101	5.073GlyThr: 5.073 ± 0.101	7.272GlyVal: 7.272 ± 0.116	1.381GlyTrp: 1.381 ± 0.051	2.198GlyTyr: 2.198 ± 0.061	0.0GlyXaa: 0.0 ± 0.0
His	2.489HisAla: 2.489 ± 0.066	0.191HisCys: 0.191 ± 0.019	1.337HisAsp: 1.337 ± 0.05	1.33HisGlu: 1.33 ± 0.045	0.645HisPhe: 0.645 ± 0.03	2.022HisGly: 2.022 ± 0.057	0.606HisHis: 0.606 ± 0.03	1.007HisIle: 1.007 ± 0.037	0.496HisLys: 0.496 ± 0.03	2.271HisLeu: 2.271 ± 0.063	0.477HisMet: 0.477 ± 0.03	0.641HisAsn: 0.641 ± 0.036	1.594HisPro: 1.594 ± 0.048	0.73HisGln: 0.73 ± 0.035	1.534HisArg: 1.534 ± 0.049	1.341HisSer: 1.341 ± 0.043	1.306HisThr: 1.306 ± 0.05	1.885HisVal: 1.885 ± 0.056	0.273HisTrp: 0.273 ± 0.02	0.508HisTyr: 0.508 ± 0.029	0.0HisXaa: 0.0 ± 0.0
Ile	6.481IleAla: 6.481 ± 0.092	0.337IleCys: 0.337 ± 0.025	3.652IleAsp: 3.652 ± 0.085	2.905IleGlu: 2.905 ± 0.074	1.528IlePhe: 1.528 ± 0.051	4.15IleGly: 4.15 ± 0.088	0.886IleHis: 0.886 ± 0.041	2.296IleIle: 2.296 ± 0.068	1.384IleLys: 1.384 ± 0.06	3.903IleLeu: 3.903 ± 0.078	0.975IleMet: 0.975 ± 0.038	1.477IleAsn: 1.477 ± 0.053	2.6IlePro: 2.6 ± 0.062	1.168IleGln: 1.168 ± 0.038	2.501IleArg: 2.501 ± 0.066	2.966IleSer: 2.966 ± 0.065	3.209IleThr: 3.209 ± 0.079	4.271IleVal: 4.271 ± 0.083	0.415IleTrp: 0.415 ± 0.03	0.968IleTyr: 0.968 ± 0.042	0.0IleXaa: 0.0 ± 0.0
Lys	3.538LysAla: 3.538 ± 0.084	0.107LysCys: 0.107 ± 0.011	1.88LysAsp: 1.88 ± 0.07	1.797LysGlu: 1.797 ± 0.063	0.81LysPhe: 0.81 ± 0.038	2.085LysGly: 2.085 ± 0.063	0.669LysHis: 0.669 ± 0.028	1.425LysIle: 1.425 ± 0.051	1.544LysLys: 1.544 ± 0.061	2.762LysLeu: 2.762 ± 0.065	0.708LysMet: 0.708 ± 0.033	1.042LysAsn: 1.042 ± 0.042	1.651LysPro: 1.651 ± 0.076	1.088LysGln: 1.088 ± 0.047	2.067LysArg: 2.067 ± 0.058	1.619LysSer: 1.619 ± 0.047	1.648LysThr: 1.648 ± 0.051	2.432LysVal: 2.432 ± 0.06	0.336LysTrp: 0.336 ± 0.022	0.615LysTyr: 0.615 ± 0.027	0.0LysXaa: 0.0 ± 0.0
Leu	12.551LeuAla: 12.551 ± 0.19	0.688LeuCys: 0.688 ± 0.037	6.03LeuAsp: 6.03 ± 0.11	5.344LeuGlu: 5.344 ± 0.101	2.832LeuPhe: 2.832 ± 0.075	8.789LeuGly: 8.789 ± 0.134	1.976LeuHis: 1.976 ± 0.049	4.897LeuIle: 4.897 ± 0.099	2.785LeuLys: 2.785 ± 0.073	8.78LeuLeu: 8.78 ± 0.137	2.033LeuMet: 2.033 ± 0.057	2.706LeuAsn: 2.706 ± 0.072	5.071LeuPro: 5.071 ± 0.079	2.606LeuGln: 2.606 ± 0.053	6.091LeuArg: 6.091 ± 0.11	6.259LeuSer: 6.259 ± 0.099	6.1LeuThr: 6.1 ± 0.104	8.094LeuVal: 8.094 ± 0.137	1.131LeuTrp: 1.131 ± 0.048	1.755LeuTyr: 1.755 ± 0.052	0.0LeuXaa: 0.0 ± 0.0
Met	2.528MetAla: 2.528 ± 0.073	0.146MetCys: 0.146 ± 0.014	1.061MetAsp: 1.061 ± 0.045	1.004MetGlu: 1.004 ± 0.036	0.702MetPhe: 0.702 ± 0.036	1.72MetGly: 1.72 ± 0.055	0.469MetHis: 0.469 ± 0.027	1.064MetIle: 1.064 ± 0.049	0.62MetLys: 0.62 ± 0.03	2.03MetLeu: 2.03 ± 0.055	0.454MetMet: 0.454 ± 0.025	0.689MetAsn: 0.689 ± 0.03	1.146MetPro: 1.146 ± 0.044	0.617MetGln: 0.617 ± 0.031	1.42MetArg: 1.42 ± 0.044	1.749MetSer: 1.749 ± 0.051	1.663MetThr: 1.663 ± 0.053	1.633MetVal: 1.633 ± 0.053	0.247MetTrp: 0.247 ± 0.02	0.375MetTyr: 0.375 ± 0.024	0.0MetXaa: 0.0 ± 0.0
Asn	3.035AsnAla: 3.035 ± 0.066	0.182AsnCys: 0.182 ± 0.015	1.528AsnAsp: 1.528 ± 0.046	1.65AsnGlu: 1.65 ± 0.054	0.917AsnPhe: 0.917 ± 0.039	2.178AsnGly: 2.178 ± 0.071	0.609AsnHis: 0.609 ± 0.025	1.226AsnIle: 1.226 ± 0.041	0.885AsnLys: 0.885 ± 0.041	2.566AsnLeu: 2.566 ± 0.063	0.558AsnMet: 0.558 ± 0.032	0.866AsnAsn: 0.866 ± 0.041	2.141AsnPro: 2.141 ± 0.053	0.942AsnGln: 0.942 ± 0.039	1.549AsnArg: 1.549 ± 0.049	1.588AsnSer: 1.588 ± 0.046	1.612AsnThr: 1.612 ± 0.059	2.162AsnVal: 2.162 ± 0.06	0.374AsnTrp: 0.374 ± 0.024	0.758AsnTyr: 0.758 ± 0.035	0.0AsnXaa: 0.0 ± 0.0
Pro	6.192ProAla: 6.192 ± 0.131	0.22ProCys: 0.22 ± 0.018	3.153ProAsp: 3.153 ± 0.079	4.445ProGlu: 4.445 ± 0.092	1.598ProPhe: 1.598 ± 0.045	4.657ProGly: 4.657 ± 0.109	1.226ProHis: 1.226 ± 0.042	2.106ProIle: 2.106 ± 0.06	1.56ProLys: 1.56 ± 0.058	4.283ProLeu: 4.283 ± 0.089	1.031ProMet: 1.031 ± 0.038	1.431ProAsn: 1.431 ± 0.045	1.795ProPro: 1.795 ± 0.072	1.941ProGln: 1.941 ± 0.058	2.988ProArg: 2.988 ± 0.074	2.979ProSer: 2.979 ± 0.071	3.156ProThr: 3.156 ± 0.066	4.607ProVal: 4.607 ± 0.089	0.674ProTrp: 0.674 ± 0.033	1.016ProTyr: 1.016 ± 0.046	0.0ProXaa: 0.0 ± 0.0
Gln	4.538GlnAla: 4.538 ± 0.09	0.182GlnCys: 0.182 ± 0.018	1.744GlnAsp: 1.744 ± 0.05	2.109GlnGlu: 2.109 ± 0.06	0.985GlnPhe: 0.985 ± 0.037	2.464GlnGly: 2.464 ± 0.057	0.777GlnHis: 0.777 ± 0.034	1.625GlnIle: 1.625 ± 0.048	0.946GlnLys: 0.946 ± 0.039	3.858GlnLeu: 3.858 ± 0.08	0.755GlnMet: 0.755 ± 0.034	0.701GlnAsn: 0.701 ± 0.036	1.928GlnPro: 1.928 ± 0.06	1.512GlnGln: 1.512 ± 0.059	2.971GlnArg: 2.971 ± 0.064	1.717GlnSer: 1.717 ± 0.059	1.631GlnThr: 1.631 ± 0.051	2.95GlnVal: 2.95 ± 0.061	0.596GlnTrp: 0.596 ± 0.034	0.638GlnTyr: 0.638 ± 0.034	0.0GlnXaa: 0.0 ± 0.0
Arg	6.985ArgAla: 6.985 ± 0.107	0.399ArgCys: 0.399 ± 0.023	3.543ArgAsp: 3.543 ± 0.082	4.516ArgGlu: 4.516 ± 0.086	2.203ArgPhe: 2.203 ± 0.059	4.639ArgGly: 4.639 ± 0.09	1.409ArgHis: 1.409 ± 0.043	3.23ArgIle: 3.23 ± 0.068	1.939ArgLys: 1.939 ± 0.055	5.991ArgLeu: 5.991 ± 0.125	1.607ArgMet: 1.607 ± 0.045	1.701ArgAsn: 1.701 ± 0.054	3.014ArgPro: 3.014 ± 0.068	2.303ArgGln: 2.303 ± 0.059	5.027ArgArg: 5.027 ± 0.116	3.899ArgSer: 3.899 ± 0.08	3.703ArgThr: 3.703 ± 0.073	5.014ArgVal: 5.014 ± 0.105	0.869ArgTrp: 0.869 ± 0.041	1.578ArgTyr: 1.578 ± 0.056	0.0ArgXaa: 0.0 ± 0.0
Ser	7.245SerAla: 7.245 ± 0.11	0.371SerCys: 0.371 ± 0.024	3.061SerAsp: 3.061 ± 0.062	3.511SerGlu: 3.511 ± 0.083	2.013SerPhe: 2.013 ± 0.053	5.57SerGly: 5.57 ± 0.091	1.341SerHis: 1.341 ± 0.05	2.667SerIle: 2.667 ± 0.064	1.477SerLys: 1.477 ± 0.049	5.845SerLeu: 5.845 ± 0.1	1.447SerMet: 1.447 ± 0.049	1.504SerAsn: 1.504 ± 0.055	3.103SerPro: 3.103 ± 0.071	2.137SerGln: 2.137 ± 0.056	3.595SerArg: 3.595 ± 0.074	4.125SerSer: 4.125 ± 0.1	4.172SerThr: 4.172 ± 0.082	5.046SerVal: 5.046 ± 0.095	0.942SerTrp: 0.942 ± 0.042	1.358SerTyr: 1.358 ± 0.049	0.0SerXaa: 0.0 ± 0.0
Thr	6.421ThrAla: 6.421 ± 0.096	0.439ThrCys: 0.439 ± 0.026	3.306ThrAsp: 3.306 ± 0.086	3.445ThrGlu: 3.445 ± 0.089	1.981ThrPhe: 1.981 ± 0.068	5.316ThrGly: 5.316 ± 0.095	1.388ThrHis: 1.388 ± 0.046	2.892ThrIle: 2.892 ± 0.075	1.67ThrLys: 1.67 ± 0.052	5.766ThrLeu: 5.766 ± 0.109	1.137ThrMet: 1.137 ± 0.037	1.587ThrAsn: 1.587 ± 0.049	3.832ThrPro: 3.832 ± 0.084	2.058ThrGln: 2.058 ± 0.055	3.372ThrArg: 3.372 ± 0.075	3.766ThrSer: 3.766 ± 0.069	3.838ThrThr: 3.838 ± 0.09	5.318ThrVal: 5.318 ± 0.11	0.898ThrTrp: 0.898 ± 0.044	1.448ThrTyr: 1.448 ± 0.041	0.0ThrXaa: 0.0 ± 0.0
Val	10.223ValAla: 10.223 ± 0.146	0.714ValCys: 0.714 ± 0.031	5.804ValAsp: 5.804 ± 0.099	5.44ValGlu: 5.44 ± 0.104	2.594ValPhe: 2.594 ± 0.064	6.667ValGly: 6.667 ± 0.125	1.812ValHis: 1.812 ± 0.047	4.398ValIle: 4.398 ± 0.091	2.276ValLys: 2.276 ± 0.061	7.928ValLeu: 7.928 ± 0.127	1.696ValMet: 1.696 ± 0.049	2.286ValAsn: 2.286 ± 0.064	3.978ValPro: 3.978 ± 0.097	2.14ValGln: 2.14 ± 0.053	5.131ValArg: 5.131 ± 0.086	5.273ValSer: 5.273 ± 0.091	5.509ValThr: 5.509 ± 0.131	8.036ValVal: 8.036 ± 0.121	1.017ValTrp: 1.017 ± 0.041	1.652ValTyr: 1.652 ± 0.048	0.0ValXaa: 0.0 ± 0.0
Trp	1.467TrpAla: 1.467 ± 0.051	0.107TrpCys: 0.107 ± 0.014	0.679TrpAsp: 0.679 ± 0.032	0.666TrpGlu: 0.666 ± 0.031	0.499TrpPhe: 0.499 ± 0.031	0.864TrpGly: 0.864 ± 0.041	0.317TrpHis: 0.317 ± 0.022	0.756TrpIle: 0.756 ± 0.034	0.346TrpLys: 0.346 ± 0.022	1.578TrpLeu: 1.578 ± 0.054	0.353TrpMet: 0.353 ± 0.024	0.425TrpAsn: 0.425 ± 0.025	0.666TrpPro: 0.666 ± 0.035	0.549TrpGln: 0.549 ± 0.031	0.949TrpArg: 0.949 ± 0.04	0.777TrpSer: 0.777 ± 0.032	0.733TrpThr: 0.733 ± 0.034	1.054TrpVal: 1.054 ± 0.042	0.324TrpTrp: 0.324 ± 0.022	0.273TrpTyr: 0.273 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.333TyrAla: 2.333 ± 0.059	0.199TyrCys: 0.199 ± 0.017	1.369TyrAsp: 1.369 ± 0.051	1.261TyrGlu: 1.261 ± 0.046	0.866TyrPhe: 0.866 ± 0.041	2.0TyrGly: 2.0 ± 0.05	0.453TyrHis: 0.453 ± 0.028	0.819TyrIle: 0.819 ± 0.036	0.492TyrLys: 0.492 ± 0.027	2.325TyrLeu: 2.325 ± 0.058	0.331TyrMet: 0.331 ± 0.022	0.597TyrAsn: 0.597 ± 0.03	1.162TyrPro: 1.162 ± 0.046	0.813TyrGln: 0.813 ± 0.037	1.578TyrArg: 1.578 ± 0.047	1.508TyrSer: 1.508 ± 0.046	1.22TyrThr: 1.22 ± 0.046	1.679TyrVal: 1.679 ± 0.055	0.302TyrTrp: 0.302 ± 0.022	0.521TyrTyr: 0.521 ± 0.025	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2045 proteins (685056 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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