Amino acid dipepetide frequency for Chiloscyllium punctatum (Brownbanded bambooshark) (Hemiscyllium punctatum)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.135AlaAla: 6.135 ± 0.046
1.254AlaCys: 1.254 ± 0.013
3.287AlaAsp: 3.287 ± 0.031
4.547AlaGlu: 4.547 ± 0.036
2.271AlaPhe: 2.271 ± 0.016
4.746AlaGly: 4.746 ± 0.04
1.485AlaHis: 1.485 ± 0.017
3.056AlaIle: 3.056 ± 0.022
3.319AlaLys: 3.319 ± 0.021
6.041AlaLeu: 6.041 ± 0.033
1.57AlaMet: 1.57 ± 0.016
2.281AlaAsn: 2.281 ± 0.017
3.121AlaPro: 3.121 ± 0.028
2.836AlaGln: 2.836 ± 0.025
4.093AlaArg: 4.093 ± 0.034
5.001AlaSer: 5.001 ± 0.029
3.36AlaThr: 3.36 ± 0.02
5.179AlaVal: 5.179 ± 0.044
0.736AlaTrp: 0.736 ± 0.011
1.398AlaTyr: 1.398 ± 0.013
0.0AlaXaa: 0.0 ± 0.0
Cys
1.261CysAla: 1.261 ± 0.015
0.646CysCys: 0.646 ± 0.012
1.183CysAsp: 1.183 ± 0.019
1.348CysGlu: 1.348 ± 0.016
0.805CysPhe: 0.805 ± 0.009
1.574CysGly: 1.574 ± 0.019
0.607CysHis: 0.607 ± 0.01
1.054CysIle: 1.054 ± 0.014
1.187CysLys: 1.187 ± 0.012
1.981CysLeu: 1.981 ± 0.017
0.445CysMet: 0.445 ± 0.006
0.908CysAsn: 0.908 ± 0.012
1.229CysPro: 1.229 ± 0.02
0.999CysGln: 0.999 ± 0.014
1.337CysArg: 1.337 ± 0.015
1.999CysSer: 1.999 ± 0.018
1.438CysThr: 1.438 ± 0.018
1.381CysVal: 1.381 ± 0.019
0.311CysTrp: 0.311 ± 0.007
0.606CysTyr: 0.606 ± 0.009
0.0CysXaa: 0.0 ± 0.0
Asp
2.93AspAla: 2.93 ± 0.028
1.209AspCys: 1.209 ± 0.013
3.456AspAsp: 3.456 ± 0.132
3.585AspGlu: 3.585 ± 0.026
1.925AspPhe: 1.925 ± 0.014
4.023AspGly: 4.023 ± 0.049
1.317AspHis: 1.317 ± 0.017
3.013AspIle: 3.013 ± 0.039
2.581AspLys: 2.581 ± 0.021
4.877AspLeu: 4.877 ± 0.032
1.145AspMet: 1.145 ± 0.011
2.013AspAsn: 2.013 ± 0.018
2.845AspPro: 2.845 ± 0.03
2.106AspGln: 2.106 ± 0.018
2.969AspArg: 2.969 ± 0.027
4.453AspSer: 4.453 ± 0.043
2.711AspThr: 2.711 ± 0.032
3.491AspVal: 3.491 ± 0.054
0.731AspTrp: 0.731 ± 0.01
1.571AspTyr: 1.571 ± 0.019
0.0AspXaa: 0.0 ± 0.0
Glu
4.352GluAla: 4.352 ± 0.029
1.382GluCys: 1.382 ± 0.021
4.093GluAsp: 4.093 ± 0.032
6.98GluGlu: 6.98 ± 0.075
2.024GluPhe: 2.024 ± 0.013
4.009GluGly: 4.009 ± 0.034
1.664GluHis: 1.664 ± 0.019
3.546GluIle: 3.546 ± 0.022
5.054GluLys: 5.054 ± 0.042
6.192GluLeu: 6.192 ± 0.044
1.814GluMet: 1.814 ± 0.016
3.289GluAsn: 3.289 ± 0.022
2.686GluPro: 2.686 ± 0.024
3.578GluGln: 3.578 ± 0.034
5.807GluArg: 5.807 ± 0.082
5.106GluSer: 5.106 ± 0.038
3.742GluThr: 3.742 ± 0.034
4.12GluVal: 4.12 ± 0.035
0.801GluTrp: 0.801 ± 0.012
1.657GluTyr: 1.657 ± 0.014
0.0GluXaa: 0.0 ± 0.0
Phe
1.993PheAla: 1.993 ± 0.017
0.856PheCys: 0.856 ± 0.009
1.792PheAsp: 1.792 ± 0.018
1.985PheGlu: 1.985 ± 0.014
1.324PhePhe: 1.324 ± 0.012
2.152PheGly: 2.152 ± 0.019
0.936PheHis: 0.936 ± 0.009
1.834PheIle: 1.834 ± 0.017
1.791PheLys: 1.791 ± 0.015
3.491PheLeu: 3.491 ± 0.027
0.727PheMet: 0.727 ± 0.009
1.434PheAsn: 1.434 ± 0.011
1.788PhePro: 1.788 ± 0.016
1.634PheGln: 1.634 ± 0.013
1.809PheArg: 1.809 ± 0.014
2.885PheSer: 2.885 ± 0.018
2.115PheThr: 2.115 ± 0.018
2.147PheVal: 2.147 ± 0.018
0.458PheTrp: 0.458 ± 0.007
1.101PheTyr: 1.101 ± 0.013
0.0PheXaa: 0.0 ± 0.0
Gly
4.307GlyAla: 4.307 ± 0.035
1.299GlyCys: 1.299 ± 0.015
3.554GlyAsp: 3.554 ± 0.039
4.32GlyGlu: 4.32 ± 0.039
2.371GlyPhe: 2.371 ± 0.022
4.85GlyGly: 4.85 ± 0.043
1.601GlyHis: 1.601 ± 0.016
3.26GlyIle: 3.26 ± 0.024
3.646GlyLys: 3.646 ± 0.022
5.612GlyLeu: 5.612 ± 0.047
1.607GlyMet: 1.607 ± 0.019
2.783GlyAsn: 2.783 ± 0.026
3.163GlyPro: 3.163 ± 0.039
2.691GlyGln: 2.691 ± 0.022
4.046GlyArg: 4.046 ± 0.032
5.47GlySer: 5.47 ± 0.032
3.859GlyThr: 3.859 ± 0.037
4.182GlyVal: 4.182 ± 0.054
0.841GlyTrp: 0.841 ± 0.012
1.963GlyTyr: 1.963 ± 0.025
0.0GlyXaa: 0.0 ± 0.0
His
1.32HisAla: 1.32 ± 0.015
0.746HisCys: 0.746 ± 0.011
1.033HisAsp: 1.033 ± 0.012
1.364HisGlu: 1.364 ± 0.017
1.001HisPhe: 1.001 ± 0.009
1.576HisGly: 1.576 ± 0.016
0.883HisHis: 0.883 ± 0.013
1.25HisIle: 1.25 ± 0.012
1.249HisLys: 1.249 ± 0.012
2.519HisLeu: 2.519 ± 0.018
0.535HisMet: 0.535 ± 0.008
0.966HisAsn: 0.966 ± 0.01
1.412HisPro: 1.412 ± 0.013
1.268HisGln: 1.268 ± 0.012
1.705HisArg: 1.705 ± 0.017
2.224HisSer: 2.224 ± 0.018
1.428HisThr: 1.428 ± 0.02
1.52HisVal: 1.52 ± 0.016
0.39HisTrp: 0.39 ± 0.008
0.781HisTyr: 0.781 ± 0.01
0.0HisXaa: 0.0 ± 0.0
Ile
3.056IleAla: 3.056 ± 0.025
1.161IleCys: 1.161 ± 0.012
2.598IleAsp: 2.598 ± 0.035
2.962IleGlu: 2.962 ± 0.021
1.864IlePhe: 1.864 ± 0.014
2.85IleGly: 2.85 ± 0.03
1.311IleHis: 1.311 ± 0.013
2.656IleIle: 2.656 ± 0.021
2.753IleLys: 2.753 ± 0.021
4.656IleLeu: 4.656 ± 0.025
1.084IleMet: 1.084 ± 0.011
2.197IleAsn: 2.197 ± 0.019
2.791IlePro: 2.791 ± 0.021
2.382IleGln: 2.382 ± 0.019
2.494IleArg: 2.494 ± 0.02
4.004IleSer: 4.004 ± 0.025
2.908IleThr: 2.908 ± 0.023
3.039IleVal: 3.039 ± 0.032
0.548IleTrp: 0.548 ± 0.008
1.411IleTyr: 1.411 ± 0.013
0.0IleXaa: 0.0 ± 0.0
Lys
3.613LysAla: 3.613 ± 0.022
1.119LysCys: 1.119 ± 0.012
3.134LysAsp: 3.134 ± 0.018
4.966LysGlu: 4.966 ± 0.041
1.633LysPhe: 1.633 ± 0.013
3.181LysGly: 3.181 ± 0.029
1.424LysHis: 1.424 ± 0.013
2.895LysIle: 2.895 ± 0.02
4.432LysLys: 4.432 ± 0.038
5.213LysLeu: 5.213 ± 0.03
1.527LysMet: 1.527 ± 0.013
2.438LysAsn: 2.438 ± 0.016
2.745LysPro: 2.745 ± 0.024
2.788LysGln: 2.788 ± 0.022
3.615LysArg: 3.615 ± 0.03
3.982LysSer: 3.982 ± 0.026
3.117LysThr: 3.117 ± 0.022
3.481LysVal: 3.481 ± 0.022
0.631LysTrp: 0.631 ± 0.007
1.578LysTyr: 1.578 ± 0.013
0.0LysXaa: 0.0 ± 0.0
Leu
5.962LeuAla: 5.962 ± 0.034
2.045LeuCys: 2.045 ± 0.021
4.629LeuAsp: 4.629 ± 0.027
6.403LeuGlu: 6.403 ± 0.04
3.102LeuPhe: 3.102 ± 0.023
5.369LeuGly: 5.369 ± 0.033
2.569LeuHis: 2.569 ± 0.02
4.075LeuIle: 4.075 ± 0.026
5.737LeuLys: 5.737 ± 0.031
9.289LeuLeu: 9.289 ± 0.054
2.072LeuMet: 2.072 ± 0.017
3.795LeuAsn: 3.795 ± 0.023
4.998LeuPro: 4.998 ± 0.029
5.275LeuGln: 5.275 ± 0.04
5.189LeuArg: 5.189 ± 0.031
7.487LeuSer: 7.487 ± 0.035
5.127LeuThr: 5.127 ± 0.031
5.272LeuVal: 5.272 ± 0.035
1.003LeuTrp: 1.003 ± 0.012
2.44LeuTyr: 2.44 ± 0.021
0.0LeuXaa: 0.0 ± 0.0
Met
1.75MetAla: 1.75 ± 0.015
0.449MetCys: 0.449 ± 0.007
1.349MetAsp: 1.349 ± 0.016
1.888MetGlu: 1.888 ± 0.016
0.802MetPhe: 0.802 ± 0.008
1.453MetGly: 1.453 ± 0.018
0.491MetHis: 0.491 ± 0.006
1.024MetIle: 1.024 ± 0.011
1.511MetLys: 1.511 ± 0.013
2.033MetLeu: 2.033 ± 0.015
0.654MetMet: 0.654 ± 0.01
0.96MetAsn: 0.96 ± 0.01
1.053MetPro: 1.053 ± 0.012
1.035MetGln: 1.035 ± 0.011
1.148MetArg: 1.148 ± 0.01
1.845MetSer: 1.845 ± 0.019
1.225MetThr: 1.225 ± 0.012
1.553MetVal: 1.553 ± 0.021
0.262MetTrp: 0.262 ± 0.005
0.608MetTyr: 0.608 ± 0.008
0.0MetXaa: 0.0 ± 0.0
Asn
2.386AsnAla: 2.386 ± 0.019
0.979AsnCys: 0.979 ± 0.012
1.915AsnAsp: 1.915 ± 0.019
2.647AsnGlu: 2.647 ± 0.024
1.455AsnPhe: 1.455 ± 0.012
2.876AsnGly: 2.876 ± 0.022
0.975AsnHis: 0.975 ± 0.009
2.449AsnIle: 2.449 ± 0.02
2.436AsnLys: 2.436 ± 0.018
3.876AsnLeu: 3.876 ± 0.024
1.025AsnMet: 1.025 ± 0.011
1.911AsnAsn: 1.911 ± 0.018
2.218AsnPro: 2.218 ± 0.02
1.828AsnGln: 1.828 ± 0.015
2.128AsnArg: 2.128 ± 0.017
3.446AsnSer: 3.446 ± 0.024
2.326AsnThr: 2.326 ± 0.026
2.646AsnVal: 2.646 ± 0.021
0.502AsnTrp: 0.502 ± 0.007
1.193AsnTyr: 1.193 ± 0.012
0.0AsnXaa: 0.0 ± 0.0
Pro
3.723ProAla: 3.723 ± 0.032
1.036ProCys: 1.036 ± 0.016
2.816ProAsp: 2.816 ± 0.032
3.621ProGlu: 3.621 ± 0.028
1.709ProPhe: 1.709 ± 0.016
4.338ProGly: 4.338 ± 0.064
1.27ProHis: 1.27 ± 0.017
2.084ProIle: 2.084 ± 0.019
2.435ProLys: 2.435 ± 0.021
4.315ProLeu: 4.315 ± 0.025
0.951ProMet: 0.951 ± 0.011
1.93ProAsn: 1.93 ± 0.019
4.046ProPro: 4.046 ± 0.044
2.239ProGln: 2.239 ± 0.02
2.784ProArg: 2.784 ± 0.023
4.772ProSer: 4.772 ± 0.034
2.805ProThr: 2.805 ± 0.026
3.804ProVal: 3.804 ± 0.034
0.555ProTrp: 0.555 ± 0.008
1.24ProTyr: 1.24 ± 0.013
0.0ProXaa: 0.0 ± 0.0
Gln
3.017GlnAla: 3.017 ± 0.024
1.104GlnCys: 1.104 ± 0.013
2.229GlnAsp: 2.229 ± 0.02
3.68GlnGlu: 3.68 ± 0.036
1.412GlnPhe: 1.412 ± 0.013
2.554GlnGly: 2.554 ± 0.022
1.356GlnHis: 1.356 ± 0.014
2.209GlnIle: 2.209 ± 0.016
2.8GlnLys: 2.8 ± 0.021
4.44GlnLeu: 4.44 ± 0.027
1.143GlnMet: 1.143 ± 0.01
2.07GlnAsn: 2.07 ± 0.017
2.322GlnPro: 2.322 ± 0.022
3.163GlnGln: 3.163 ± 0.04
2.965GlnArg: 2.965 ± 0.019
3.557GlnSer: 3.557 ± 0.028
2.547GlnThr: 2.547 ± 0.022
2.547GlnVal: 2.547 ± 0.019
0.589GlnTrp: 0.589 ± 0.009
1.23GlnTyr: 1.23 ± 0.013
0.0GlnXaa: 0.0 ± 0.0
Arg
4.245ArgAla: 4.245 ± 0.038
1.271ArgCys: 1.271 ± 0.015
3.161ArgAsp: 3.161 ± 0.029
5.656ArgGlu: 5.656 ± 0.079
1.872ArgPhe: 1.872 ± 0.015
3.706ArgGly: 3.706 ± 0.031
1.538ArgHis: 1.538 ± 0.013
2.621ArgIle: 2.621 ± 0.017
3.833ArgLys: 3.833 ± 0.03
5.066ArgLeu: 5.066 ± 0.025
1.305ArgMet: 1.305 ± 0.012
2.411ArgAsn: 2.411 ± 0.018
2.826ArgPro: 2.826 ± 0.023
2.66ArgGln: 2.66 ± 0.016
4.504ArgArg: 4.504 ± 0.033
4.406ArgSer: 4.406 ± 0.033
3.016ArgThr: 3.016 ± 0.023
3.316ArgVal: 3.316 ± 0.022
0.688ArgTrp: 0.688 ± 0.01
1.509ArgTyr: 1.509 ± 0.015
0.0ArgXaa: 0.0 ± 0.0
Ser
5.425SerAla: 5.425 ± 0.029
1.766SerCys: 1.766 ± 0.018
4.261SerAsp: 4.261 ± 0.035
5.617SerGlu: 5.617 ± 0.042
2.741SerPhe: 2.741 ± 0.016
5.672SerGly: 5.672 ± 0.038
1.94SerHis: 1.94 ± 0.016
3.561SerIle: 3.561 ± 0.02
4.182SerLys: 4.182 ± 0.027
7.413SerLeu: 7.413 ± 0.038
1.697SerMet: 1.697 ± 0.014
3.258SerAsn: 3.258 ± 0.021
4.903SerPro: 4.903 ± 0.043
3.682SerGln: 3.682 ± 0.03
4.499SerArg: 4.499 ± 0.031
8.388SerSer: 8.388 ± 0.055
4.676SerThr: 4.676 ± 0.033
5.512SerVal: 5.512 ± 0.042
0.958SerTrp: 0.958 ± 0.011
1.945SerTyr: 1.945 ± 0.014
0.0SerXaa: 0.0 ± 0.0
Thr
4.06ThrAla: 4.06 ± 0.032
1.218ThrCys: 1.218 ± 0.017
3.041ThrAsp: 3.041 ± 0.034
4.012ThrGlu: 4.012 ± 0.036
2.02ThrPhe: 2.02 ± 0.014
4.062ThrGly: 4.062 ± 0.038
1.226ThrHis: 1.226 ± 0.013
2.728ThrIle: 2.728 ± 0.018
2.745ThrLys: 2.745 ± 0.019
5.09ThrLeu: 5.09 ± 0.031
1.289ThrMet: 1.289 ± 0.018
2.093ThrAsn: 2.093 ± 0.021
3.14ThrPro: 3.14 ± 0.03
2.183ThrGln: 2.183 ± 0.021
2.686ThrArg: 2.686 ± 0.02
4.567ThrSer: 4.567 ± 0.032
3.196ThrThr: 3.196 ± 0.041
4.576ThrVal: 4.576 ± 0.033
0.652ThrTrp: 0.652 ± 0.009
1.33ThrTyr: 1.33 ± 0.011
0.0ThrXaa: 0.0 ± 0.0
Val
4.126ValAla: 4.126 ± 0.037
1.536ValCys: 1.536 ± 0.016
3.417ValAsp: 3.417 ± 0.058
3.974ValGlu: 3.974 ± 0.03
2.319ValPhe: 2.319 ± 0.023
4.151ValGly: 4.151 ± 0.053
1.573ValHis: 1.573 ± 0.015
3.336ValIle: 3.336 ± 0.033
3.556ValLys: 3.556 ± 0.021
6.062ValLeu: 6.062 ± 0.045
1.575ValMet: 1.575 ± 0.021
2.653ValAsn: 2.653 ± 0.022
3.45ValPro: 3.45 ± 0.032
2.88ValGln: 2.88 ± 0.02
3.405ValArg: 3.405 ± 0.022
5.279ValSer: 5.279 ± 0.038
4.096ValThr: 4.096 ± 0.027
4.301ValVal: 4.301 ± 0.054
0.787ValTrp: 0.787 ± 0.013
1.746ValTyr: 1.746 ± 0.017
0.0ValXaa: 0.0 ± 0.0
Trp
0.736TrpAla: 0.736 ± 0.011
0.295TrpCys: 0.295 ± 0.008
0.712TrpAsp: 0.712 ± 0.012
0.805TrpGlu: 0.805 ± 0.01
0.434TrpPhe: 0.434 ± 0.007
0.705TrpGly: 0.705 ± 0.011
0.271TrpHis: 0.271 ± 0.005
0.634TrpIle: 0.634 ± 0.008
0.803TrpLys: 0.803 ± 0.009
1.116TrpLeu: 1.116 ± 0.012
0.318TrpMet: 0.318 ± 0.005
0.59TrpAsn: 0.59 ± 0.008
0.466TrpPro: 0.466 ± 0.006
0.498TrpGln: 0.498 ± 0.006
0.784TrpArg: 0.784 ± 0.009
0.986TrpSer: 0.986 ± 0.013
0.689TrpThr: 0.689 ± 0.009
0.644TrpVal: 0.644 ± 0.01
0.192TrpTrp: 0.192 ± 0.005
0.354TrpTyr: 0.354 ± 0.007
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.317TyrAla: 1.317 ± 0.011
0.926TyrCys: 0.926 ± 0.019
1.288TyrAsp: 1.288 ± 0.013
1.537TyrGlu: 1.537 ± 0.017
1.168TyrPhe: 1.168 ± 0.011
1.581TyrGly: 1.581 ± 0.015
0.733TyrHis: 0.733 ± 0.008
1.442TyrIle: 1.442 ± 0.012
1.462TyrLys: 1.462 ± 0.015
2.556TyrLeu: 2.556 ± 0.02
0.609TyrMet: 0.609 ± 0.009
1.239TyrAsn: 1.239 ± 0.013
1.273TyrPro: 1.273 ± 0.015
1.21TyrGln: 1.21 ± 0.011
1.64TyrArg: 1.64 ± 0.017
2.24TyrSer: 2.24 ± 0.018
1.533TyrThr: 1.533 ± 0.017
1.51TyrVal: 1.51 ± 0.013
0.397TyrTrp: 0.397 ± 0.008
0.973TyrTyr: 0.973 ± 0.012
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 33497 proteins (12024568 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski