Amino acid dipepetide frequency for Botryotinia fuckeliana (strain BcDW1) (Noble rot fungus) (Botrytis cinerea)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.393AlaAla: 7.393 ± 0.061	0.909AlaCys: 0.909 ± 0.014	3.683AlaAsp: 3.683 ± 0.028	4.83AlaGlu: 4.83 ± 0.042	2.888AlaPhe: 2.888 ± 0.025	5.22AlaGly: 5.22 ± 0.042	1.557AlaHis: 1.557 ± 0.018	4.36AlaIle: 4.36 ± 0.032	4.21AlaLys: 4.21 ± 0.036	6.841AlaLeu: 6.841 ± 0.043	1.835AlaMet: 1.835 ± 0.02	3.092AlaAsn: 3.092 ± 0.023	4.366AlaPro: 4.366 ± 0.042	3.115AlaGln: 3.115 ± 0.03	4.11AlaArg: 4.11 ± 0.03	6.962AlaSer: 6.962 ± 0.045	5.043AlaThr: 5.043 ± 0.037	4.552AlaVal: 4.552 ± 0.032	1.004AlaTrp: 1.004 ± 0.016	2.053AlaTyr: 2.053 ± 0.019	0.0AlaXaa: 0.0 ± 0.0
Cys	0.832CysAla: 0.832 ± 0.013	0.209CysCys: 0.209 ± 0.007	0.607CysAsp: 0.607 ± 0.011	0.599CysGlu: 0.599 ± 0.011	0.482CysPhe: 0.482 ± 0.01	0.897CysGly: 0.897 ± 0.017	0.273CysHis: 0.273 ± 0.007	0.675CysIle: 0.675 ± 0.012	0.549CysLys: 0.549 ± 0.011	1.111CysLeu: 1.111 ± 0.017	0.259CysMet: 0.259 ± 0.007	0.432CysAsn: 0.432 ± 0.009	0.599CysPro: 0.599 ± 0.012	0.399CysGln: 0.399 ± 0.009	0.599CysArg: 0.599 ± 0.012	0.884CysSer: 0.884 ± 0.016	0.665CysThr: 0.665 ± 0.012	0.7CysVal: 0.7 ± 0.01	0.181CysTrp: 0.181 ± 0.006	0.337CysTyr: 0.337 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	4.182AspAla: 4.182 ± 0.031	0.613AspCys: 0.613 ± 0.012	4.197AspAsp: 4.197 ± 0.045	4.69AspGlu: 4.69 ± 0.041	2.255AspPhe: 2.255 ± 0.021	3.934AspGly: 3.934 ± 0.034	1.162AspHis: 1.162 ± 0.015	3.354AspIle: 3.354 ± 0.025	2.458AspLys: 2.458 ± 0.023	4.945AspLeu: 4.945 ± 0.03	1.249AspMet: 1.249 ± 0.016	2.13AspAsn: 2.13 ± 0.021	2.975AspPro: 2.975 ± 0.023	1.798AspGln: 1.798 ± 0.019	2.779AspArg: 2.779 ± 0.029	4.369AspSer: 4.369 ± 0.031	3.007AspThr: 3.007 ± 0.023	3.463AspVal: 3.463 ± 0.03	0.854AspTrp: 0.854 ± 0.014	1.631AspTyr: 1.631 ± 0.019	0.0AspXaa: 0.0 ± 0.0
Glu	5.045GluAla: 5.045 ± 0.041	0.613GluCys: 0.613 ± 0.012	4.495GluAsp: 4.495 ± 0.039	6.368GluGlu: 6.368 ± 0.061	2.114GluPhe: 2.114 ± 0.019	4.061GluGly: 4.061 ± 0.03	1.323GluHis: 1.323 ± 0.016	3.771GluIle: 3.771 ± 0.031	4.577GluLys: 4.577 ± 0.038	5.203GluLeu: 5.203 ± 0.039	1.679GluMet: 1.679 ± 0.017	2.964GluAsn: 2.964 ± 0.027	2.615GluPro: 2.615 ± 0.034	2.41GluGln: 2.41 ± 0.026	4.049GluArg: 4.049 ± 0.038	4.83GluSer: 4.83 ± 0.037	3.587GluThr: 3.587 ± 0.029	3.778GluVal: 3.778 ± 0.028	0.922GluTrp: 0.922 ± 0.013	1.788GluTyr: 1.788 ± 0.019	0.0GluXaa: 0.0 ± 0.0
Phe	2.854PheAla: 2.854 ± 0.029	0.538PheCys: 0.538 ± 0.009	2.287PheAsp: 2.287 ± 0.024	2.329PheGlu: 2.329 ± 0.02	1.538PhePhe: 1.538 ± 0.02	2.904PheGly: 2.904 ± 0.031	0.866PheHis: 0.866 ± 0.012	1.881PheIle: 1.881 ± 0.018	1.71PheLys: 1.71 ± 0.019	3.32PheLeu: 3.32 ± 0.028	0.825PheMet: 0.825 ± 0.012	1.614PheAsn: 1.614 ± 0.018	1.934PhePro: 1.934 ± 0.018	1.417PheGln: 1.417 ± 0.017	1.764PheArg: 1.764 ± 0.019	3.072PheSer: 3.072 ± 0.027	2.231PheThr: 2.231 ± 0.021	2.242PheVal: 2.242 ± 0.023	0.618PheTrp: 0.618 ± 0.011	1.087PheTyr: 1.087 ± 0.013	0.0PheXaa: 0.0 ± 0.0
Gly	4.796GlyAla: 4.796 ± 0.039	0.804GlyCys: 0.804 ± 0.013	3.553GlyAsp: 3.553 ± 0.029	3.992GlyGlu: 3.992 ± 0.03	2.758GlyPhe: 2.758 ± 0.025	5.928GlyGly: 5.928 ± 0.075	1.562GlyHis: 1.562 ± 0.017	3.783GlyIle: 3.783 ± 0.031	3.968GlyLys: 3.968 ± 0.035	5.752GlyLeu: 5.752 ± 0.039	1.715GlyMet: 1.715 ± 0.019	2.995GlyAsn: 2.995 ± 0.026	2.987GlyPro: 2.987 ± 0.025	2.322GlyGln: 2.322 ± 0.026	3.817GlyArg: 3.817 ± 0.034	5.839GlySer: 5.839 ± 0.049	4.035GlyThr: 4.035 ± 0.028	4.253GlyVal: 4.253 ± 0.034	1.126GlyTrp: 1.126 ± 0.017	2.183GlyTyr: 2.183 ± 0.024	0.0GlyXaa: 0.0 ± 0.0
His	1.568HisAla: 1.568 ± 0.019	0.294HisCys: 0.294 ± 0.009	1.249HisAsp: 1.249 ± 0.016	1.355HisGlu: 1.355 ± 0.017	0.874HisPhe: 0.874 ± 0.013	1.565HisGly: 1.565 ± 0.02	0.771HisHis: 0.771 ± 0.014	1.227HisIle: 1.227 ± 0.016	1.002HisLys: 1.002 ± 0.017	2.006HisLeu: 2.006 ± 0.019	0.46HisMet: 0.46 ± 0.01	0.936HisAsn: 0.936 ± 0.013	1.479HisPro: 1.479 ± 0.019	0.968HisGln: 0.968 ± 0.014	1.317HisArg: 1.317 ± 0.018	1.877HisSer: 1.877 ± 0.022	1.309HisThr: 1.309 ± 0.017	1.239HisVal: 1.239 ± 0.015	0.302HisTrp: 0.302 ± 0.008	0.669HisTyr: 0.669 ± 0.01	0.0HisXaa: 0.0 ± 0.0
Ile	4.31IleAla: 4.31 ± 0.031	0.754IleCys: 0.754 ± 0.013	3.199IleAsp: 3.199 ± 0.028	3.461IleGlu: 3.461 ± 0.026	2.189IlePhe: 2.189 ± 0.022	3.453IleGly: 3.453 ± 0.031	1.252IleHis: 1.252 ± 0.015	2.973IleIle: 2.973 ± 0.025	2.702IleLys: 2.702 ± 0.026	4.936IleLeu: 4.936 ± 0.038	1.122IleMet: 1.122 ± 0.014	2.239IleAsn: 2.239 ± 0.019	3.472IlePro: 3.472 ± 0.028	2.094IleGln: 2.094 ± 0.022	2.762IleArg: 2.762 ± 0.026	4.681IleSer: 4.681 ± 0.036	3.277IleThr: 3.277 ± 0.031	3.316IleVal: 3.316 ± 0.029	0.764IleTrp: 0.764 ± 0.011	1.572IleTyr: 1.572 ± 0.019	0.0IleXaa: 0.0 ± 0.0
Lys	4.385LysAla: 4.385 ± 0.036	0.537LysCys: 0.537 ± 0.011	3.172LysAsp: 3.172 ± 0.03	4.154LysGlu: 4.154 ± 0.039	1.726LysPhe: 1.726 ± 0.017	3.325LysGly: 3.325 ± 0.029	1.178LysHis: 1.178 ± 0.014	2.94LysIle: 2.94 ± 0.026	4.123LysLys: 4.123 ± 0.048	4.452LysLeu: 4.452 ± 0.029	1.198LysMet: 1.198 ± 0.017	2.305LysAsn: 2.305 ± 0.019	2.794LysPro: 2.794 ± 0.024	1.906LysGln: 1.906 ± 0.024	3.579LysArg: 3.579 ± 0.036	4.406LysSer: 4.406 ± 0.03	3.152LysThr: 3.152 ± 0.025	3.109LysVal: 3.109 ± 0.026	0.758LysTrp: 0.758 ± 0.012	1.518LysTyr: 1.518 ± 0.018	0.0LysXaa: 0.0 ± 0.0
Leu	6.884LeuAla: 6.884 ± 0.042	1.08LeuCys: 1.08 ± 0.016	4.872LeuAsp: 4.872 ± 0.034	5.681LeuGlu: 5.681 ± 0.04	3.128LeuPhe: 3.128 ± 0.029	5.625LeuGly: 5.625 ± 0.039	1.991LeuHis: 1.991 ± 0.021	4.134LeuIle: 4.134 ± 0.035	4.645LeuLys: 4.645 ± 0.031	7.672LeuLeu: 7.672 ± 0.058	1.753LeuMet: 1.753 ± 0.018	3.467LeuAsn: 3.467 ± 0.026	5.218LeuPro: 5.218 ± 0.036	3.69LeuGln: 3.69 ± 0.028	5.034LeuArg: 5.034 ± 0.036	7.29LeuSer: 7.29 ± 0.042	4.717LeuThr: 4.717 ± 0.033	4.819LeuVal: 4.819 ± 0.035	1.101LeuTrp: 1.101 ± 0.018	2.238LeuTyr: 2.238 ± 0.023	0.0LeuXaa: 0.0 ± 0.0
Met	2.071MetAla: 2.071 ± 0.02	0.228MetCys: 0.228 ± 0.006	1.285MetAsp: 1.285 ± 0.015	1.484MetGlu: 1.484 ± 0.016	0.758MetPhe: 0.758 ± 0.011	1.593MetGly: 1.593 ± 0.02	0.462MetHis: 0.462 ± 0.009	1.154MetIle: 1.154 ± 0.016	1.211MetLys: 1.211 ± 0.016	1.708MetLeu: 1.708 ± 0.019	0.617MetMet: 0.617 ± 0.01	0.983MetAsn: 0.983 ± 0.014	1.205MetPro: 1.205 ± 0.015	0.85MetGln: 0.85 ± 0.014	1.214MetArg: 1.214 ± 0.015	1.979MetSer: 1.979 ± 0.018	1.285MetThr: 1.285 ± 0.015	1.275MetVal: 1.275 ± 0.014	0.252MetTrp: 0.252 ± 0.007	0.526MetTyr: 0.526 ± 0.01	0.0MetXaa: 0.0 ± 0.0
Asn	3.319AsnAla: 3.319 ± 0.024	0.469AsnCys: 0.469 ± 0.01	2.285AsnAsp: 2.285 ± 0.02	2.504AsnGlu: 2.504 ± 0.023	1.656AsnPhe: 1.656 ± 0.017	3.478AsnGly: 3.478 ± 0.033	1.009AsnHis: 1.009 ± 0.015	2.509AsnIle: 2.509 ± 0.021	1.889AsnLys: 1.889 ± 0.02	3.636AsnLeu: 3.636 ± 0.027	0.943AsnMet: 0.943 ± 0.012	1.989AsnAsn: 1.989 ± 0.026	2.646AsnPro: 2.646 ± 0.025	1.577AsnGln: 1.577 ± 0.02	2.068AsnArg: 2.068 ± 0.02	3.682AsnSer: 3.682 ± 0.033	2.694AsnThr: 2.694 ± 0.021	2.495AsnVal: 2.495 ± 0.022	0.596AsnTrp: 0.596 ± 0.01	1.259AsnTyr: 1.259 ± 0.016	0.0AsnXaa: 0.0 ± 0.0
Pro	4.426ProAla: 4.426 ± 0.036	0.432ProCys: 0.432 ± 0.01	2.807ProAsp: 2.807 ± 0.025	3.694ProGlu: 3.694 ± 0.032	1.96ProPhe: 1.96 ± 0.022	3.503ProGly: 3.503 ± 0.033	1.23ProHis: 1.23 ± 0.017	3.001ProIle: 3.001 ± 0.029	2.93ProLys: 2.93 ± 0.027	4.508ProLeu: 4.508 ± 0.038	1.055ProMet: 1.055 ± 0.016	2.458ProAsn: 2.458 ± 0.025	4.688ProPro: 4.688 ± 0.07	2.454ProGln: 2.454 ± 0.029	3.091ProArg: 3.091 ± 0.028	6.051ProSer: 6.051 ± 0.047	4.066ProThr: 4.066 ± 0.033	3.222ProVal: 3.222 ± 0.027	0.655ProTrp: 0.655 ± 0.012	1.511ProTyr: 1.511 ± 0.017	0.0ProXaa: 0.0 ± 0.0
Gln	3.123GlnAla: 3.123 ± 0.028	0.386GlnCys: 0.386 ± 0.009	1.981GlnAsp: 1.981 ± 0.021	2.472GlnGlu: 2.472 ± 0.026	1.323GlnPhe: 1.323 ± 0.016	2.241GlnGly: 2.241 ± 0.027	0.969GlnHis: 0.969 ± 0.016	2.121GlnIle: 2.121 ± 0.021	2.269GlnLys: 2.269 ± 0.025	3.156GlnLeu: 3.156 ± 0.026	0.879GlnMet: 0.879 ± 0.016	1.912GlnAsn: 1.912 ± 0.023	2.212GlnPro: 2.212 ± 0.028	2.246GlnGln: 2.246 ± 0.048	2.354GlnArg: 2.354 ± 0.023	3.322GlnSer: 3.322 ± 0.03	2.324GlnThr: 2.324 ± 0.022	2.05GlnVal: 2.05 ± 0.022	0.525GlnTrp: 0.525 ± 0.01	1.223GlnTyr: 1.223 ± 0.017	0.0GlnXaa: 0.0 ± 0.0
Arg	3.958ArgAla: 3.958 ± 0.03	0.579ArgCys: 0.579 ± 0.01	3.115ArgAsp: 3.115 ± 0.031	3.961ArgGlu: 3.961 ± 0.036	1.91ArgPhe: 1.91 ± 0.02	3.632ArgGly: 3.632 ± 0.034	1.286ArgHis: 1.286 ± 0.016	2.904ArgIle: 2.904 ± 0.025	3.689ArgLys: 3.689 ± 0.03	4.622ArgLeu: 4.622 ± 0.034	1.245ArgMet: 1.245 ± 0.015	2.51ArgAsn: 2.51 ± 0.024	2.998ArgPro: 2.998 ± 0.029	2.295ArgGln: 2.295 ± 0.023	4.384ArgArg: 4.384 ± 0.042	4.588ArgSer: 4.588 ± 0.039	3.001ArgThr: 3.001 ± 0.026	2.962ArgVal: 2.962 ± 0.023	0.778ArgTrp: 0.778 ± 0.013	1.518ArgTyr: 1.518 ± 0.017	0.0ArgXaa: 0.0 ± 0.0
Ser	6.393SerAla: 6.393 ± 0.045	0.839SerCys: 0.839 ± 0.015	4.416SerAsp: 4.416 ± 0.028	4.676SerGlu: 4.676 ± 0.035	3.149SerPhe: 3.149 ± 0.027	5.706SerGly: 5.706 ± 0.044	2.034SerHis: 2.034 ± 0.02	4.831SerIle: 4.831 ± 0.038	4.464SerLys: 4.464 ± 0.032	7.196SerLeu: 7.196 ± 0.044	1.828SerMet: 1.828 ± 0.018	3.868SerAsn: 3.868 ± 0.031	5.722SerPro: 5.722 ± 0.054	3.513SerGln: 3.513 ± 0.031	4.842SerArg: 4.842 ± 0.044	10.171SerSer: 10.171 ± 0.099	6.439SerThr: 6.439 ± 0.053	4.482SerVal: 4.482 ± 0.038	1.072SerTrp: 1.072 ± 0.015	2.262SerTyr: 2.262 ± 0.023	0.0SerXaa: 0.0 ± 0.0
Thr	4.801ThrAla: 4.801 ± 0.036	0.711ThrCys: 0.711 ± 0.011	2.79ThrAsp: 2.79 ± 0.023	3.272ThrGlu: 3.272 ± 0.028	2.351ThrPhe: 2.351 ± 0.02	4.178ThrGly: 4.178 ± 0.035	1.303ThrHis: 1.303 ± 0.018	3.612ThrIle: 3.612 ± 0.026	3.042ThrLys: 3.042 ± 0.027	5.209ThrLeu: 5.209 ± 0.034	1.199ThrMet: 1.199 ± 0.014	2.538ThrAsn: 2.538 ± 0.027	4.527ThrPro: 4.527 ± 0.035	2.188ThrGln: 2.188 ± 0.019	2.899ThrArg: 2.899 ± 0.025	6.223ThrSer: 6.223 ± 0.051	4.679ThrThr: 4.679 ± 0.046	3.438ThrVal: 3.438 ± 0.029	0.808ThrTrp: 0.808 ± 0.013	1.695ThrTyr: 1.695 ± 0.018	0.0ThrXaa: 0.0 ± 0.0
Val	4.672ValAla: 4.672 ± 0.033	0.709ValCys: 0.709 ± 0.012	3.493ValAsp: 3.493 ± 0.026	4.096ValGlu: 4.096 ± 0.03	2.262ValPhe: 2.262 ± 0.022	3.891ValGly: 3.891 ± 0.03	1.224ValHis: 1.224 ± 0.016	3.016ValIle: 3.016 ± 0.029	3.138ValLys: 3.138 ± 0.027	5.021ValLeu: 5.021 ± 0.036	1.29ValMet: 1.29 ± 0.016	2.302ValAsn: 2.302 ± 0.02	3.245ValPro: 3.245 ± 0.029	2.172ValGln: 2.172 ± 0.019	2.954ValArg: 2.954 ± 0.024	4.496ValSer: 4.496 ± 0.029	3.351ValThr: 3.351 ± 0.028	3.941ValVal: 3.941 ± 0.035	0.789ValTrp: 0.789 ± 0.012	1.622ValTyr: 1.622 ± 0.019	0.0ValXaa: 0.0 ± 0.0
Trp	0.991TrpAla: 0.991 ± 0.013	0.181TrpCys: 0.181 ± 0.006	0.859TrpAsp: 0.859 ± 0.015	0.9TrpGlu: 0.9 ± 0.015	0.511TrpPhe: 0.511 ± 0.01	0.947TrpGly: 0.947 ± 0.016	0.311TrpHis: 0.311 ± 0.007	0.793TrpIle: 0.793 ± 0.012	0.872TrpLys: 0.872 ± 0.012	1.197TrpLeu: 1.197 ± 0.014	0.371TrpMet: 0.371 ± 0.008	0.678TrpAsn: 0.678 ± 0.012	0.532TrpPro: 0.532 ± 0.01	0.509TrpGln: 0.509 ± 0.011	0.812TrpArg: 0.812 ± 0.014	0.989TrpSer: 0.989 ± 0.015	0.858TrpThr: 0.858 ± 0.014	0.814TrpVal: 0.814 ± 0.011	0.26TrpTrp: 0.26 ± 0.008	0.406TrpTyr: 0.406 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.021TyrAla: 2.021 ± 0.021	0.403TyrCys: 0.403 ± 0.009	1.701TyrAsp: 1.701 ± 0.02	1.672TyrGlu: 1.672 ± 0.018	1.2TyrPhe: 1.2 ± 0.014	2.088TyrGly: 2.088 ± 0.025	0.707TyrHis: 0.707 ± 0.013	1.492TyrIle: 1.492 ± 0.017	1.267TyrLys: 1.267 ± 0.016	2.544TyrLeu: 2.544 ± 0.022	0.616TyrMet: 0.616 ± 0.012	1.292TyrAsn: 1.292 ± 0.018	1.529TyrPro: 1.529 ± 0.018	1.167TyrGln: 1.167 ± 0.017	1.508TyrArg: 1.508 ± 0.017	2.189TyrSer: 2.189 ± 0.022	1.742TyrThr: 1.742 ± 0.017	1.533TyrVal: 1.533 ± 0.017	0.427TyrTrp: 0.427 ± 0.01	0.952TyrTyr: 0.952 ± 0.015	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 11022 proteins (5548963 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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