Amino acid dipepetide frequency for Desulfarculus baarsii (strain ATCC 33931 / DSM 2075 / LMG 7858 / VKM B-1802 / 2st14)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	18.208AlaAla: 18.208 ± 0.244	1.597AlaCys: 1.597 ± 0.043	6.749AlaAsp: 6.749 ± 0.086	7.518AlaGlu: 7.518 ± 0.091	3.715AlaPhe: 3.715 ± 0.066	11.008AlaGly: 11.008 ± 0.118	2.377AlaHis: 2.377 ± 0.055	5.114AlaIle: 5.114 ± 0.079	4.898AlaLys: 4.898 ± 0.084	14.575AlaLeu: 14.575 ± 0.17	4.203AlaMet: 4.203 ± 0.061	2.703AlaAsn: 2.703 ± 0.056	5.795AlaPro: 5.795 ± 0.1	6.084AlaGln: 6.084 ± 0.105	8.983AlaArg: 8.983 ± 0.102	5.369AlaSer: 5.369 ± 0.093	4.644AlaThr: 4.644 ± 0.074	9.166AlaVal: 9.166 ± 0.112	1.666AlaTrp: 1.666 ± 0.045	2.446AlaTyr: 2.446 ± 0.046	0.0AlaXaa: 0.0 ± 0.0
Cys	1.437CysAla: 1.437 ± 0.035	0.242CysCys: 0.242 ± 0.015	0.562CysAsp: 0.562 ± 0.025	0.471CysGlu: 0.471 ± 0.022	0.447CysPhe: 0.447 ± 0.018	1.411CysGly: 1.411 ± 0.042	0.399CysHis: 0.399 ± 0.03	0.376CysIle: 0.376 ± 0.021	0.339CysLys: 0.339 ± 0.017	1.612CysLeu: 1.612 ± 0.039	0.233CysMet: 0.233 ± 0.015	0.294CysAsn: 0.294 ± 0.017	0.92CysPro: 0.92 ± 0.035	0.672CysGln: 0.672 ± 0.024	1.051CysArg: 1.051 ± 0.034	0.54CysSer: 0.54 ± 0.024	0.473CysThr: 0.473 ± 0.024	0.748CysVal: 0.748 ± 0.026	0.176CysTrp: 0.176 ± 0.011	0.299CysTyr: 0.299 ± 0.018	0.0CysXaa: 0.0 ± 0.0
Asp	5.214AspAla: 5.214 ± 0.064	0.681AspCys: 0.681 ± 0.028	3.502AspAsp: 3.502 ± 0.061	3.959AspGlu: 3.959 ± 0.072	2.192AspPhe: 2.192 ± 0.049	5.011AspGly: 5.011 ± 0.076	1.236AspHis: 1.236 ± 0.031	2.668AspIle: 2.668 ± 0.054	2.172AspLys: 2.172 ± 0.044	6.269AspLeu: 6.269 ± 0.085	1.55AspMet: 1.55 ± 0.045	1.371AspAsn: 1.371 ± 0.039	3.217AspPro: 3.217 ± 0.059	2.739AspGln: 2.739 ± 0.055	3.238AspArg: 3.238 ± 0.06	2.066AspSer: 2.066 ± 0.049	1.651AspThr: 1.651 ± 0.04	3.805AspVal: 3.805 ± 0.06	0.826AspTrp: 0.826 ± 0.031	1.675AspTyr: 1.675 ± 0.045	0.0AspXaa: 0.0 ± 0.0
Glu	7.751GluAla: 7.751 ± 0.093	0.428GluCys: 0.428 ± 0.021	2.671GluAsp: 2.671 ± 0.049	3.276GluGlu: 3.276 ± 0.064	1.782GluPhe: 1.782 ± 0.044	4.099GluGly: 4.099 ± 0.063	1.222GluHis: 1.222 ± 0.029	3.006GluIle: 3.006 ± 0.059	2.501GluLys: 2.501 ± 0.054	7.31GluLeu: 7.31 ± 0.095	1.779GluMet: 1.779 ± 0.042	1.636GluAsn: 1.636 ± 0.044	2.78GluPro: 2.78 ± 0.053	2.578GluGln: 2.578 ± 0.053	4.756GluArg: 4.756 ± 0.07	2.406GluSer: 2.406 ± 0.05	2.333GluThr: 2.333 ± 0.045	4.044GluVal: 4.044 ± 0.065	0.448GluTrp: 0.448 ± 0.021	1.121GluTyr: 1.121 ± 0.033	0.0GluXaa: 0.0 ± 0.0
Phe	3.615PheAla: 3.615 ± 0.065	0.636PheCys: 0.636 ± 0.026	2.299PheAsp: 2.299 ± 0.048	1.883PheGlu: 1.883 ± 0.042	1.565PhePhe: 1.565 ± 0.04	3.274PheGly: 3.274 ± 0.063	0.68PheHis: 0.68 ± 0.027	1.61PheIle: 1.61 ± 0.04	1.189PheLys: 1.189 ± 0.037	3.243PheLeu: 3.243 ± 0.063	0.949PheMet: 0.949 ± 0.034	1.143PheAsn: 1.143 ± 0.033	1.288PhePro: 1.288 ± 0.038	1.052PheGln: 1.052 ± 0.027	1.928PheArg: 1.928 ± 0.047	2.008PheSer: 2.008 ± 0.046	1.568PheThr: 1.568 ± 0.039	2.556PheVal: 2.556 ± 0.052	0.559PheTrp: 0.559 ± 0.021	0.976PheTyr: 0.976 ± 0.032	0.0PheXaa: 0.0 ± 0.0
Gly	9.051GlyAla: 9.051 ± 0.113	1.243GlyCys: 1.243 ± 0.036	4.324GlyAsp: 4.324 ± 0.067	4.264GlyGlu: 4.264 ± 0.06	3.098GlyPhe: 3.098 ± 0.055	8.273GlyGly: 8.273 ± 0.135	2.02GlyHis: 2.02 ± 0.045	2.358GlyIle: 2.358 ± 0.055	3.454GlyLys: 3.454 ± 0.063	11.782GlyLeu: 11.782 ± 0.119	2.24GlyMet: 2.24 ± 0.05	1.754GlyAsn: 1.754 ± 0.044	4.55GlyPro: 4.55 ± 0.079	5.329GlyGln: 5.329 ± 0.081	7.78GlyArg: 7.78 ± 0.097	3.537GlySer: 3.537 ± 0.085	2.402GlyThr: 2.402 ± 0.052	7.351GlyVal: 7.351 ± 0.087	1.359GlyTrp: 1.359 ± 0.041	2.247GlyTyr: 2.247 ± 0.051	0.0GlyXaa: 0.0 ± 0.0
His	2.066HisAla: 2.066 ± 0.041	0.328HisCys: 0.328 ± 0.017	1.302HisAsp: 1.302 ± 0.038	1.093HisGlu: 1.093 ± 0.03	0.821HisPhe: 0.821 ± 0.026	2.177HisGly: 2.177 ± 0.041	0.54HisHis: 0.54 ± 0.028	0.855HisIle: 0.855 ± 0.03	0.669HisLys: 0.669 ± 0.024	2.207HisLeu: 2.207 ± 0.048	0.478HisMet: 0.478 ± 0.021	0.564HisAsn: 0.564 ± 0.022	1.181HisPro: 1.181 ± 0.031	0.806HisGln: 0.806 ± 0.026	1.231HisArg: 1.231 ± 0.032	0.818HisSer: 0.818 ± 0.029	0.74HisThr: 0.74 ± 0.025	1.301HisVal: 1.301 ± 0.033	0.266HisTrp: 0.266 ± 0.016	0.571HisTyr: 0.571 ± 0.026	0.0HisXaa: 0.0 ± 0.0
Ile	4.806IleAla: 4.806 ± 0.057	0.689IleCys: 0.689 ± 0.027	3.215IleAsp: 3.215 ± 0.06	2.919IleGlu: 2.919 ± 0.049	1.707IlePhe: 1.707 ± 0.042	3.758IleGly: 3.758 ± 0.065	0.959IleHis: 0.959 ± 0.029	2.448IleIle: 2.448 ± 0.053	1.956IleLys: 1.956 ± 0.044	4.033IleLeu: 4.033 ± 0.066	1.212IleMet: 1.212 ± 0.042	1.625IleAsn: 1.625 ± 0.04	1.731IlePro: 1.731 ± 0.048	1.335IleGln: 1.335 ± 0.033	2.294IleArg: 2.294 ± 0.055	2.512IleSer: 2.512 ± 0.052	2.233IleThr: 2.233 ± 0.055	3.425IleVal: 3.425 ± 0.06	0.505IleTrp: 0.505 ± 0.019	1.157IleTyr: 1.157 ± 0.038	0.0IleXaa: 0.0 ± 0.0
Lys	4.694LysAla: 4.694 ± 0.085	0.346LysCys: 0.346 ± 0.019	1.951LysAsp: 1.951 ± 0.043	1.91LysGlu: 1.91 ± 0.046	0.981LysPhe: 0.981 ± 0.035	2.822LysGly: 2.822 ± 0.05	0.636LysHis: 0.636 ± 0.024	2.016LysIle: 2.016 ± 0.042	1.912LysLys: 1.912 ± 0.053	3.894LysLeu: 3.894 ± 0.064	1.057LysMet: 1.057 ± 0.034	1.16LysAsn: 1.16 ± 0.034	2.05LysPro: 2.05 ± 0.049	1.265LysGln: 1.265 ± 0.041	2.453LysArg: 2.453 ± 0.051	1.696LysSer: 1.696 ± 0.041	1.838LysThr: 1.838 ± 0.042	2.783LysVal: 2.783 ± 0.051	0.359LysTrp: 0.359 ± 0.019	0.833LysTyr: 0.833 ± 0.025	0.0LysXaa: 0.0 ± 0.0
Leu	18.075LeuAla: 18.075 ± 0.192	1.646LeuCys: 1.646 ± 0.035	6.533LeuAsp: 6.533 ± 0.088	7.111LeuGlu: 7.111 ± 0.098	3.369LeuPhe: 3.369 ± 0.057	10.662LeuGly: 10.662 ± 0.128	1.883LeuHis: 1.883 ± 0.048	4.822LeuIle: 4.822 ± 0.076	3.565LeuLys: 3.565 ± 0.055	11.205LeuLeu: 11.205 ± 0.143	2.449LeuMet: 2.449 ± 0.049	2.448LeuAsn: 2.448 ± 0.042	5.681LeuPro: 5.681 ± 0.083	2.824LeuGln: 2.824 ± 0.056	8.125LeuArg: 8.125 ± 0.094	5.713LeuSer: 5.713 ± 0.071	5.399LeuThr: 5.399 ± 0.081	7.388LeuVal: 7.388 ± 0.104	1.485LeuTrp: 1.485 ± 0.045	2.066LeuTyr: 2.066 ± 0.045	0.0LeuXaa: 0.0 ± 0.0
Met	4.16MetAla: 4.16 ± 0.065	0.227MetCys: 0.227 ± 0.014	1.483MetAsp: 1.483 ± 0.034	1.52MetGlu: 1.52 ± 0.043	0.724MetPhe: 0.724 ± 0.031	2.432MetGly: 2.432 ± 0.052	0.439MetHis: 0.439 ± 0.02	1.44MetIle: 1.44 ± 0.036	1.061MetLys: 1.061 ± 0.034	2.659MetLeu: 2.659 ± 0.054	0.559MetMet: 0.559 ± 0.025	0.804MetAsn: 0.804 ± 0.027	1.349MetPro: 1.349 ± 0.035	0.76MetGln: 0.76 ± 0.027	1.597MetArg: 1.597 ± 0.039	1.553MetSer: 1.553 ± 0.039	1.446MetThr: 1.446 ± 0.035	1.928MetVal: 1.928 ± 0.045	0.183MetTrp: 0.183 ± 0.011	0.348MetTyr: 0.348 ± 0.017	0.0MetXaa: 0.0 ± 0.0
Asn	2.589AsnAla: 2.589 ± 0.059	0.353AsnCys: 0.353 ± 0.02	1.327AsnAsp: 1.327 ± 0.037	1.193AsnGlu: 1.193 ± 0.031	0.974AsnPhe: 0.974 ± 0.03	1.898AsnGly: 1.898 ± 0.053	0.583AsnHis: 0.583 ± 0.022	1.501AsnIle: 1.501 ± 0.038	0.971AsnLys: 0.971 ± 0.028	3.001AsnLeu: 3.001 ± 0.053	0.711AsnMet: 0.711 ± 0.026	0.784AsnAsn: 0.784 ± 0.029	1.729AsnPro: 1.729 ± 0.041	1.113AsnGln: 1.113 ± 0.038	1.487AsnArg: 1.487 ± 0.036	1.104AsnSer: 1.104 ± 0.042	1.057AsnThr: 1.057 ± 0.038	1.886AsnVal: 1.886 ± 0.049	0.351AsnTrp: 0.351 ± 0.02	0.765AsnTyr: 0.765 ± 0.03	0.0AsnXaa: 0.0 ± 0.0
Pro	6.868ProAla: 6.868 ± 0.106	0.547ProCys: 0.547 ± 0.023	3.108ProAsp: 3.108 ± 0.056	3.878ProGlu: 3.878 ± 0.059	1.612ProPhe: 1.612 ± 0.039	5.116ProGly: 5.116 ± 0.082	0.982ProHis: 0.982 ± 0.028	1.804ProIle: 1.804 ± 0.038	1.755ProLys: 1.755 ± 0.042	5.368ProLeu: 5.368 ± 0.08	1.233ProMet: 1.233 ± 0.032	1.171ProAsn: 1.171 ± 0.034	3.244ProPro: 3.244 ± 0.065	1.924ProGln: 1.924 ± 0.038	3.195ProArg: 3.195 ± 0.054	2.243ProSer: 2.243 ± 0.048	2.303ProThr: 2.303 ± 0.047	3.49ProVal: 3.49 ± 0.05	0.837ProTrp: 0.837 ± 0.031	1.108ProTyr: 1.108 ± 0.035	0.0ProXaa: 0.0 ± 0.0
Gln	6.94GlnAla: 6.94 ± 0.111	0.438GlnCys: 0.438 ± 0.024	1.842GlnAsp: 1.842 ± 0.044	2.195GlnGlu: 2.195 ± 0.045	1.013GlnPhe: 1.013 ± 0.03	3.438GlnGly: 3.438 ± 0.058	0.562GlnHis: 0.562 ± 0.026	1.978GlnIle: 1.978 ± 0.036	1.668GlnLys: 1.668 ± 0.041	3.371GlnLeu: 3.371 ± 0.052	1.141GlnMet: 1.141 ± 0.037	1.199GlnAsn: 1.199 ± 0.035	2.053GlnPro: 2.053 ± 0.047	1.389GlnGln: 1.389 ± 0.047	3.308GlnArg: 3.308 ± 0.07	1.965GlnSer: 1.965 ± 0.043	2.136GlnThr: 2.136 ± 0.038	2.927GlnVal: 2.927 ± 0.05	0.578GlnTrp: 0.578 ± 0.023	0.795GlnTyr: 0.795 ± 0.028	0.0GlnXaa: 0.0 ± 0.0
Arg	8.261ArgAla: 8.261 ± 0.106	0.718ArgCys: 0.718 ± 0.028	3.264ArgAsp: 3.264 ± 0.056	3.769ArgGlu: 3.769 ± 0.062	2.607ArgPhe: 2.607 ± 0.05	5.085ArgGly: 5.085 ± 0.076	1.605ArgHis: 1.605 ± 0.04	2.98ArgIle: 2.98 ± 0.058	2.236ArgLys: 2.236 ± 0.049	9.78ArgLeu: 9.78 ± 0.127	1.864ArgMet: 1.864 ± 0.038	1.42ArgAsn: 1.42 ± 0.039	4.516ArgPro: 4.516 ± 0.069	4.306ArgGln: 4.306 ± 0.074	6.398ArgArg: 6.398 ± 0.091	2.391ArgSer: 2.391 ± 0.046	2.274ArgThr: 2.274 ± 0.048	4.852ArgVal: 4.852 ± 0.064	1.042ArgTrp: 1.042 ± 0.033	1.574ArgTyr: 1.574 ± 0.038	0.0ArgXaa: 0.0 ± 0.0
Ser	5.193SerAla: 5.193 ± 0.079	0.568SerCys: 0.568 ± 0.022	2.368SerAsp: 2.368 ± 0.047	2.257SerGlu: 2.257 ± 0.055	1.821SerPhe: 1.821 ± 0.04	4.759SerGly: 4.759 ± 0.083	1.025SerHis: 1.025 ± 0.031	1.907SerIle: 1.907 ± 0.045	1.353SerLys: 1.353 ± 0.036	5.532SerLeu: 5.532 ± 0.082	1.186SerMet: 1.186 ± 0.036	1.026SerAsn: 1.026 ± 0.037	2.604SerPro: 2.604 ± 0.051	2.039SerGln: 2.039 ± 0.044	3.126SerArg: 3.126 ± 0.05	2.245SerSer: 2.245 ± 0.062	1.97SerThr: 1.97 ± 0.047	3.099SerVal: 3.099 ± 0.061	0.614SerTrp: 0.614 ± 0.024	1.191SerTyr: 1.191 ± 0.04	0.0SerXaa: 0.0 ± 0.0
Thr	5.044ThrAla: 5.044 ± 0.075	0.479ThrCys: 0.479 ± 0.021	1.977ThrAsp: 1.977 ± 0.041	1.913ThrGlu: 1.913 ± 0.038	1.362ThrPhe: 1.362 ± 0.039	3.883ThrGly: 3.883 ± 0.061	0.796ThrHis: 0.796 ± 0.027	2.341ThrIle: 2.341 ± 0.046	1.411ThrLys: 1.411 ± 0.039	4.357ThrLeu: 4.357 ± 0.069	1.214ThrMet: 1.214 ± 0.035	1.166ThrAsn: 1.166 ± 0.035	2.857ThrPro: 2.857 ± 0.057	1.243ThrGln: 1.243 ± 0.034	2.361ThrArg: 2.361 ± 0.051	2.107ThrSer: 2.107 ± 0.049	2.099ThrThr: 2.099 ± 0.051	3.192ThrVal: 3.192 ± 0.065	0.47ThrTrp: 0.47 ± 0.022	0.965ThrTyr: 0.965 ± 0.032	0.0ThrXaa: 0.0 ± 0.0
Val	9.102ValAla: 9.102 ± 0.09	1.057ValCys: 1.057 ± 0.029	4.458ValAsp: 4.458 ± 0.063	5.014ValGlu: 5.014 ± 0.065	2.734ValPhe: 2.734 ± 0.054	6.307ValGly: 6.307 ± 0.077	1.274ValHis: 1.274 ± 0.035	3.939ValIle: 3.939 ± 0.067	2.466ValLys: 2.466 ± 0.05	7.647ValLeu: 7.647 ± 0.095	1.865ValMet: 1.865 ± 0.047	2.044ValAsn: 2.044 ± 0.048	2.282ValPro: 2.282 ± 0.054	1.91ValGln: 1.91 ± 0.044	4.574ValArg: 4.574 ± 0.075	3.842ValSer: 3.842 ± 0.067	3.244ValThr: 3.244 ± 0.059	6.348ValVal: 6.348 ± 0.085	0.846ValTrp: 0.846 ± 0.033	1.655ValTyr: 1.655 ± 0.037	0.0ValXaa: 0.0 ± 0.0
Trp	1.538TrpAla: 1.538 ± 0.038	0.135TrpCys: 0.135 ± 0.011	0.666TrpAsp: 0.666 ± 0.028	0.588TrpGlu: 0.588 ± 0.023	0.448TrpPhe: 0.448 ± 0.022	0.987TrpGly: 0.987 ± 0.035	0.229TrpHis: 0.229 ± 0.015	0.451TrpIle: 0.451 ± 0.023	0.318TrpLys: 0.318 ± 0.018	1.929TrpLeu: 1.929 ± 0.049	0.262TrpMet: 0.262 ± 0.018	0.325TrpAsn: 0.325 ± 0.017	0.887TrpPro: 0.887 ± 0.035	0.524TrpGln: 0.524 ± 0.021	1.483TrpArg: 1.483 ± 0.046	0.695TrpSer: 0.695 ± 0.028	0.5TrpThr: 0.5 ± 0.022	0.745TrpVal: 0.745 ± 0.028	0.249TrpTrp: 0.249 ± 0.018	0.222TrpTyr: 0.222 ± 0.015	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.204TyrAla: 2.204 ± 0.041	0.343TyrCys: 0.343 ± 0.017	1.441TyrAsp: 1.441 ± 0.034	1.194TyrGlu: 1.194 ± 0.039	1.05TyrPhe: 1.05 ± 0.032	2.017TyrGly: 2.017 ± 0.053	0.564TyrHis: 0.564 ± 0.021	0.902TyrIle: 0.902 ± 0.029	0.761TyrLys: 0.761 ± 0.029	2.679TyrLeu: 2.679 ± 0.052	0.49TyrMet: 0.49 ± 0.022	0.741TyrAsn: 0.741 ± 0.033	1.069TyrPro: 1.069 ± 0.034	1.043TyrGln: 1.043 ± 0.027	1.577TyrArg: 1.577 ± 0.041	1.073TyrSer: 1.073 ± 0.033	0.927TyrThr: 0.927 ± 0.037	1.576TyrVal: 1.576 ± 0.039	0.361TyrTrp: 0.361 ± 0.018	0.797TyrTyr: 0.797 ± 0.029	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3268 proteins (1096967 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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