Amino acid dipepetide frequency for Flavisolibacter ginsengisoli DSM 18119

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.796AlaAla: 5.796 ± 0.096	0.735AlaCys: 0.735 ± 0.024	3.639AlaAsp: 3.639 ± 0.051	3.879AlaGlu: 3.879 ± 0.059	3.524AlaPhe: 3.524 ± 0.057	5.536AlaGly: 5.536 ± 0.08	1.265AlaHis: 1.265 ± 0.033	5.426AlaIle: 5.426 ± 0.078	4.04AlaLys: 4.04 ± 0.064	6.666AlaLeu: 6.666 ± 0.078	1.757AlaMet: 1.757 ± 0.043	3.419AlaAsn: 3.419 ± 0.056	2.408AlaPro: 2.408 ± 0.049	2.7AlaGln: 2.7 ± 0.059	2.785AlaArg: 2.785 ± 0.05	4.852AlaSer: 4.852 ± 0.074	4.064AlaThr: 4.064 ± 0.073	4.471AlaVal: 4.471 ± 0.06	0.886AlaTrp: 0.886 ± 0.025	2.603AlaTyr: 2.603 ± 0.051	0.0AlaXaa: 0.0 ± 0.0
Cys	0.546CysAla: 0.546 ± 0.033	0.14CysCys: 0.14 ± 0.01	0.409CysAsp: 0.409 ± 0.02	0.42CysGlu: 0.42 ± 0.017	0.512CysPhe: 0.512 ± 0.02	0.719CysGly: 0.719 ± 0.025	0.208CysHis: 0.208 ± 0.015	0.742CysIle: 0.742 ± 0.026	0.514CysLys: 0.514 ± 0.017	0.839CysLeu: 0.839 ± 0.023	0.243CysMet: 0.243 ± 0.013	0.473CysAsn: 0.473 ± 0.02	0.375CysPro: 0.375 ± 0.019	0.282CysGln: 0.282 ± 0.015	0.338CysArg: 0.338 ± 0.016	0.671CysSer: 0.671 ± 0.022	0.515CysThr: 0.515 ± 0.021	0.445CysVal: 0.445 ± 0.017	0.109CysTrp: 0.109 ± 0.009	0.356CysTyr: 0.356 ± 0.018	0.0CysXaa: 0.0 ± 0.0
Asp	3.701AspAla: 3.701 ± 0.057	0.426AspCys: 0.426 ± 0.019	2.336AspAsp: 2.336 ± 0.046	3.113AspGlu: 3.113 ± 0.052	2.697AspPhe: 2.697 ± 0.048	3.456AspGly: 3.456 ± 0.071	1.115AspHis: 1.115 ± 0.03	3.876AspIle: 3.876 ± 0.052	3.7AspLys: 3.7 ± 0.061	4.805AspLeu: 4.805 ± 0.066	1.145AspMet: 1.145 ± 0.031	2.67AspAsn: 2.67 ± 0.05	2.229AspPro: 2.229 ± 0.041	1.699AspGln: 1.699 ± 0.034	1.969AspArg: 1.969 ± 0.041	3.172AspSer: 3.172 ± 0.059	2.655AspThr: 2.655 ± 0.049	3.396AspVal: 3.396 ± 0.056	0.753AspTrp: 0.753 ± 0.028	2.316AspTyr: 2.316 ± 0.045	0.0AspXaa: 0.0 ± 0.0
Glu	4.148GluAla: 4.148 ± 0.067	0.379GluCys: 0.379 ± 0.019	2.73GluAsp: 2.73 ± 0.054	4.201GluGlu: 4.201 ± 0.08	2.394GluPhe: 2.394 ± 0.045	3.569GluGly: 3.569 ± 0.054	1.129GluHis: 1.129 ± 0.03	3.987GluIle: 3.987 ± 0.06	5.106GluLys: 5.106 ± 0.082	5.65GluLeu: 5.65 ± 0.076	1.6GluMet: 1.6 ± 0.037	3.217GluAsn: 3.217 ± 0.055	1.721GluPro: 1.721 ± 0.037	2.429GluGln: 2.429 ± 0.046	2.519GluArg: 2.519 ± 0.048	2.843GluSer: 2.843 ± 0.045	2.891GluThr: 2.891 ± 0.048	3.89GluVal: 3.89 ± 0.065	0.751GluTrp: 0.751 ± 0.022	2.186GluTyr: 2.186 ± 0.044	0.0GluXaa: 0.0 ± 0.0
Phe	3.182PheAla: 3.182 ± 0.054	0.464PheCys: 0.464 ± 0.02	2.751PheAsp: 2.751 ± 0.043	2.616PheGlu: 2.616 ± 0.048	2.694PhePhe: 2.694 ± 0.058	3.408PheGly: 3.408 ± 0.048	0.962PheHis: 0.962 ± 0.03	3.896PheIle: 3.896 ± 0.064	2.961PheLys: 2.961 ± 0.051	4.656PheLeu: 4.656 ± 0.078	1.085PheMet: 1.085 ± 0.03	2.766PheAsn: 2.766 ± 0.05	1.892PhePro: 1.892 ± 0.04	1.657PheGln: 1.657 ± 0.042	1.955PheArg: 1.955 ± 0.036	3.859PheSer: 3.859 ± 0.056	3.336PheThr: 3.336 ± 0.056	2.732PheVal: 2.732 ± 0.053	0.618PheTrp: 0.618 ± 0.022	2.072PheTyr: 2.072 ± 0.042	0.0PheXaa: 0.0 ± 0.0
Gly	4.548GlyAla: 4.548 ± 0.069	0.77GlyCys: 0.77 ± 0.036	3.405GlyAsp: 3.405 ± 0.062	3.412GlyGlu: 3.412 ± 0.052	3.573GlyPhe: 3.573 ± 0.056	5.013GlyGly: 5.013 ± 0.095	1.315GlyHis: 1.315 ± 0.028	5.541GlyIle: 5.541 ± 0.077	5.381GlyLys: 5.381 ± 0.072	6.087GlyLeu: 6.087 ± 0.075	1.839GlyMet: 1.839 ± 0.041	3.945GlyAsn: 3.945 ± 0.072	1.644GlyPro: 1.644 ± 0.037	2.343GlyGln: 2.343 ± 0.051	2.652GlyArg: 2.652 ± 0.046	4.667GlySer: 4.667 ± 0.087	4.289GlyThr: 4.289 ± 0.081	4.348GlyVal: 4.348 ± 0.058	1.016GlyTrp: 1.016 ± 0.033	3.047GlyTyr: 3.047 ± 0.054	0.0GlyXaa: 0.0 ± 0.0
His	1.215HisAla: 1.215 ± 0.03	0.225HisCys: 0.225 ± 0.014	0.9HisAsp: 0.9 ± 0.027	1.033HisGlu: 1.033 ± 0.027	1.206HisPhe: 1.206 ± 0.029	1.247HisGly: 1.247 ± 0.033	0.562HisHis: 0.562 ± 0.025	1.49HisIle: 1.49 ± 0.034	1.12HisLys: 1.12 ± 0.029	2.022HisLeu: 2.022 ± 0.045	0.47HisMet: 0.47 ± 0.018	0.981HisAsn: 0.981 ± 0.029	1.1HisPro: 1.1 ± 0.03	0.808HisGln: 0.808 ± 0.027	0.817HisArg: 0.817 ± 0.026	1.268HisSer: 1.268 ± 0.036	1.076HisThr: 1.076 ± 0.034	1.071HisVal: 1.071 ± 0.028	0.282HisTrp: 0.282 ± 0.015	0.976HisTyr: 0.976 ± 0.029	0.0HisXaa: 0.0 ± 0.0
Ile	5.629IleAla: 5.629 ± 0.073	0.769IleCys: 0.769 ± 0.026	4.142IleAsp: 4.142 ± 0.058	4.217IleGlu: 4.217 ± 0.065	3.055IlePhe: 3.055 ± 0.056	4.873IleGly: 4.873 ± 0.066	1.466IleHis: 1.466 ± 0.031	5.379IleIle: 5.379 ± 0.079	4.625IleLys: 4.625 ± 0.063	6.462IleLeu: 6.462 ± 0.088	1.431IleMet: 1.431 ± 0.034	4.203IleAsn: 4.203 ± 0.064	3.284IlePro: 3.284 ± 0.052	2.517IleGln: 2.517 ± 0.042	3.129IleArg: 3.129 ± 0.047	5.131IleSer: 5.131 ± 0.07	4.505IleThr: 4.505 ± 0.066	4.406IleVal: 4.406 ± 0.063	0.748IleTrp: 0.748 ± 0.025	2.71IleTyr: 2.71 ± 0.045	0.0IleXaa: 0.0 ± 0.0
Lys	5.047LysAla: 5.047 ± 0.073	0.376LysCys: 0.376 ± 0.019	4.101LysAsp: 4.101 ± 0.062	5.521LysGlu: 5.521 ± 0.083	2.391LysPhe: 2.391 ± 0.038	4.849LysGly: 4.849 ± 0.064	1.214LysHis: 1.214 ± 0.03	4.523LysIle: 4.523 ± 0.074	5.631LysLys: 5.631 ± 0.075	5.854LysLeu: 5.854 ± 0.073	1.956LysMet: 1.956 ± 0.043	4.005LysAsn: 4.005 ± 0.06	2.722LysPro: 2.722 ± 0.047	2.738LysGln: 2.738 ± 0.047	2.846LysArg: 2.846 ± 0.046	3.538LysSer: 3.538 ± 0.056	3.965LysThr: 3.965 ± 0.058	4.493LysVal: 4.493 ± 0.063	0.962LysTrp: 0.962 ± 0.025	2.643LysTyr: 2.643 ± 0.044	0.0LysXaa: 0.0 ± 0.0
Leu	6.42LeuAla: 6.42 ± 0.072	0.87LeuCys: 0.87 ± 0.025	4.499LeuAsp: 4.499 ± 0.059	5.001LeuGlu: 5.001 ± 0.08	5.138LeuPhe: 5.138 ± 0.078	5.666LeuGly: 5.666 ± 0.084	2.002LeuHis: 2.002 ± 0.041	6.095LeuIle: 6.095 ± 0.087	6.735LeuLys: 6.735 ± 0.077	9.886LeuLeu: 9.886 ± 0.117	2.172LeuMet: 2.172 ± 0.039	5.045LeuAsn: 5.045 ± 0.062	4.24LeuPro: 4.24 ± 0.054	4.3LeuGln: 4.3 ± 0.059	3.783LeuArg: 3.783 ± 0.058	6.798LeuSer: 6.798 ± 0.076	5.045LeuThr: 5.045 ± 0.067	6.181LeuVal: 6.181 ± 0.074	1.023LeuTrp: 1.023 ± 0.028	3.328LeuTyr: 3.328 ± 0.054	0.0LeuXaa: 0.0 ± 0.0
Met	1.943MetAla: 1.943 ± 0.04	0.158MetCys: 0.158 ± 0.011	1.364MetAsp: 1.364 ± 0.031	1.605MetGlu: 1.605 ± 0.036	0.819MetPhe: 0.819 ± 0.025	1.546MetGly: 1.546 ± 0.035	0.531MetHis: 0.531 ± 0.02	1.609MetIle: 1.609 ± 0.033	2.141MetLys: 2.141 ± 0.043	2.039MetLeu: 2.039 ± 0.039	0.644MetMet: 0.644 ± 0.022	1.432MetAsn: 1.432 ± 0.031	1.141MetPro: 1.141 ± 0.03	1.092MetGln: 1.092 ± 0.027	1.02MetArg: 1.02 ± 0.024	1.376MetSer: 1.376 ± 0.033	1.103MetThr: 1.103 ± 0.03	1.618MetVal: 1.618 ± 0.033	0.208MetTrp: 0.208 ± 0.013	0.704MetTyr: 0.704 ± 0.02	0.0MetXaa: 0.0 ± 0.0
Asn	3.933AsnAla: 3.933 ± 0.061	0.497AsnCys: 0.497 ± 0.021	2.851AsnAsp: 2.851 ± 0.05	3.167AsnGlu: 3.167 ± 0.044	2.623AsnPhe: 2.623 ± 0.052	4.168AsnGly: 4.168 ± 0.078	0.966AsnHis: 0.966 ± 0.033	4.114AsnIle: 4.114 ± 0.058	3.778AsnLys: 3.778 ± 0.049	4.674AsnLeu: 4.674 ± 0.062	1.224AsnMet: 1.224 ± 0.027	3.505AsnAsn: 3.505 ± 0.067	2.573AsnPro: 2.573 ± 0.048	1.87AsnGln: 1.87 ± 0.041	2.312AsnArg: 2.312 ± 0.044	3.43AsnSer: 3.43 ± 0.056	3.218AsnThr: 3.218 ± 0.06	3.074AsnVal: 3.074 ± 0.053	0.808AsnTrp: 0.808 ± 0.028	2.55AsnTyr: 2.55 ± 0.051	0.0AsnXaa: 0.0 ± 0.0
Pro	3.171ProAla: 3.171 ± 0.062	0.249ProCys: 0.249 ± 0.015	2.28ProAsp: 2.28 ± 0.05	2.535ProGlu: 2.535 ± 0.046	2.127ProPhe: 2.127 ± 0.039	3.279ProGly: 3.279 ± 0.052	0.716ProHis: 0.716 ± 0.025	2.362ProIle: 2.362 ± 0.042	2.162ProLys: 2.162 ± 0.045	3.501ProLeu: 3.501 ± 0.047	0.814ProMet: 0.814 ± 0.024	1.944ProAsn: 1.944 ± 0.038	1.279ProPro: 1.279 ± 0.043	1.41ProGln: 1.41 ± 0.041	1.266ProArg: 1.266 ± 0.028	2.631ProSer: 2.631 ± 0.039	2.096ProThr: 2.096 ± 0.048	3.466ProVal: 3.466 ± 0.055	0.484ProTrp: 0.484 ± 0.022	1.618ProTyr: 1.618 ± 0.038	0.0ProXaa: 0.0 ± 0.0
Gln	2.513GlnAla: 2.513 ± 0.045	0.277GlnCys: 0.277 ± 0.02	1.581GlnAsp: 1.581 ± 0.035	2.143GlnGlu: 2.143 ± 0.046	1.84GlnPhe: 1.84 ± 0.043	2.217GlnGly: 2.217 ± 0.044	0.846GlnHis: 0.846 ± 0.029	2.121GlnIle: 2.121 ± 0.043	2.951GlnLys: 2.951 ± 0.045	4.191GlnLeu: 4.191 ± 0.064	1.041GlnMet: 1.041 ± 0.029	1.889GlnAsn: 1.889 ± 0.04	1.605GlnPro: 1.605 ± 0.04	2.059GlnGln: 2.059 ± 0.047	1.636GlnArg: 1.636 ± 0.04	2.297GlnSer: 2.297 ± 0.044	2.035GlnThr: 2.035 ± 0.034	2.735GlnVal: 2.735 ± 0.049	0.522GlnTrp: 0.522 ± 0.019	1.653GlnTyr: 1.653 ± 0.031	0.0GlnXaa: 0.0 ± 0.0
Arg	2.148ArgAla: 2.148 ± 0.041	0.271ArgCys: 0.271 ± 0.014	1.964ArgAsp: 1.964 ± 0.042	2.377ArgGlu: 2.377 ± 0.046	2.272ArgPhe: 2.272 ± 0.043	2.232ArgGly: 2.232 ± 0.044	0.822ArgHis: 0.822 ± 0.024	3.261ArgIle: 3.261 ± 0.051	3.173ArgLys: 3.173 ± 0.049	3.938ArgLeu: 3.938 ± 0.061	1.144ArgMet: 1.144 ± 0.031	2.443ArgAsn: 2.443 ± 0.047	1.407ArgPro: 1.407 ± 0.033	1.696ArgGln: 1.696 ± 0.036	1.743ArgArg: 1.743 ± 0.04	2.632ArgSer: 2.632 ± 0.045	2.174ArgThr: 2.174 ± 0.038	2.336ArgVal: 2.336 ± 0.047	0.498ArgTrp: 0.498 ± 0.017	1.815ArgTyr: 1.815 ± 0.039	0.0ArgXaa: 0.0 ± 0.0
Ser	4.365SerAla: 4.365 ± 0.065	0.671SerCys: 0.671 ± 0.024	3.093SerAsp: 3.093 ± 0.051	3.064SerGlu: 3.064 ± 0.052	4.13SerPhe: 4.13 ± 0.066	4.94SerGly: 4.94 ± 0.085	1.234SerHis: 1.234 ± 0.03	5.188SerIle: 5.188 ± 0.068	4.015SerLys: 4.015 ± 0.06	6.707SerLeu: 6.707 ± 0.068	1.577SerMet: 1.577 ± 0.037	3.513SerAsn: 3.513 ± 0.062	2.394SerPro: 2.394 ± 0.046	2.184SerGln: 2.184 ± 0.043	2.562SerArg: 2.562 ± 0.044	4.655SerSer: 4.655 ± 0.081	3.708SerThr: 3.708 ± 0.063	4.083SerVal: 4.083 ± 0.057	0.864SerTrp: 0.864 ± 0.025	2.781SerTyr: 2.781 ± 0.055	0.0SerXaa: 0.0 ± 0.0
Thr	4.358ThrAla: 4.358 ± 0.072	0.434ThrCys: 0.434 ± 0.02	3.016ThrAsp: 3.016 ± 0.054	2.944ThrGlu: 2.944 ± 0.047	2.52ThrPhe: 2.52 ± 0.054	4.798ThrGly: 4.798 ± 0.071	1.06ThrHis: 1.06 ± 0.028	4.713ThrIle: 4.713 ± 0.069	3.143ThrLys: 3.143 ± 0.052	5.085ThrLeu: 5.085 ± 0.072	1.097ThrMet: 1.097 ± 0.031	2.888ThrAsn: 2.888 ± 0.063	2.676ThrPro: 2.676 ± 0.055	1.785ThrGln: 1.785 ± 0.035	2.228ThrArg: 2.228 ± 0.045	3.943ThrSer: 3.943 ± 0.065	3.658ThrThr: 3.658 ± 0.08	4.002ThrVal: 4.002 ± 0.075	0.77ThrTrp: 0.77 ± 0.03	2.211ThrTyr: 2.211 ± 0.048	0.0ThrXaa: 0.0 ± 0.0
Val	4.484ValAla: 4.484 ± 0.061	0.625ValCys: 0.625 ± 0.022	3.346ValAsp: 3.346 ± 0.063	3.397ValGlu: 3.397 ± 0.053	3.215ValPhe: 3.215 ± 0.051	3.767ValGly: 3.767 ± 0.058	1.277ValHis: 1.277 ± 0.036	4.865ValIle: 4.865 ± 0.066	4.351ValLys: 4.351 ± 0.06	6.133ValLeu: 6.133 ± 0.064	1.602ValMet: 1.602 ± 0.032	3.661ValAsn: 3.661 ± 0.051	2.633ValPro: 2.633 ± 0.049	2.414ValGln: 2.414 ± 0.049	2.421ValArg: 2.421 ± 0.039	4.362ValSer: 4.362 ± 0.063	3.819ValThr: 3.819 ± 0.063	4.268ValVal: 4.268 ± 0.072	0.737ValTrp: 0.737 ± 0.022	2.522ValTyr: 2.522 ± 0.05	0.0ValXaa: 0.0 ± 0.0
Trp	0.692TrpAla: 0.692 ± 0.026	0.117TrpCys: 0.117 ± 0.008	0.666TrpAsp: 0.666 ± 0.029	0.644TrpGlu: 0.644 ± 0.018	0.597TrpPhe: 0.597 ± 0.022	0.856TrpGly: 0.856 ± 0.034	0.302TrpHis: 0.302 ± 0.016	0.883TrpIle: 0.883 ± 0.026	1.116TrpLys: 1.116 ± 0.034	1.228TrpLeu: 1.228 ± 0.036	0.44TrpMet: 0.44 ± 0.019	0.827TrpAsn: 0.827 ± 0.025	0.363TrpPro: 0.363 ± 0.018	0.571TrpGln: 0.571 ± 0.02	0.495TrpArg: 0.495 ± 0.018	0.818TrpSer: 0.818 ± 0.028	0.682TrpThr: 0.682 ± 0.024	0.759TrpVal: 0.759 ± 0.025	0.248TrpTrp: 0.248 ± 0.014	0.498TrpTyr: 0.498 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.613TyrAla: 2.613 ± 0.048	0.401TyrCys: 0.401 ± 0.02	2.16TyrAsp: 2.16 ± 0.047	2.052TyrGlu: 2.052 ± 0.039	2.234TyrPhe: 2.234 ± 0.042	2.695TyrGly: 2.695 ± 0.05	0.877TyrHis: 0.877 ± 0.026	2.609TyrIle: 2.609 ± 0.051	2.731TyrLys: 2.731 ± 0.043	3.807TyrLeu: 3.807 ± 0.049	0.814TyrMet: 0.814 ± 0.022	2.51TyrAsn: 2.51 ± 0.048	1.703TyrPro: 1.703 ± 0.034	1.597TyrGln: 1.597 ± 0.04	1.87TyrArg: 1.87 ± 0.036	2.782TyrSer: 2.782 ± 0.051	2.494TyrThr: 2.494 ± 0.051	2.125TyrVal: 2.125 ± 0.043	0.515TyrTrp: 0.515 ± 0.021	1.914TyrTyr: 1.914 ± 0.042	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4178 proteins (1362833 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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