Amino acid dipepetide frequency for Pantoea stewartii subsp. stewartii DC283

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	10.94AlaAla: 10.94 ± 0.137	1.167AlaCys: 1.167 ± 0.039	5.282AlaAsp: 5.282 ± 0.067	6.218AlaGlu: 6.218 ± 0.083	3.751AlaPhe: 3.751 ± 0.057	7.942AlaGly: 7.942 ± 0.086	1.938AlaHis: 1.938 ± 0.038	5.694AlaIle: 5.694 ± 0.076	3.692AlaLys: 3.692 ± 0.067	12.67AlaLeu: 12.67 ± 0.141	3.061AlaMet: 3.061 ± 0.053	2.916AlaAsn: 2.916 ± 0.056	3.648AlaPro: 3.648 ± 0.059	4.724AlaGln: 4.724 ± 0.074	6.317AlaArg: 6.317 ± 0.092	6.008AlaSer: 6.008 ± 0.079	4.88AlaThr: 4.88 ± 0.068	6.918AlaVal: 6.918 ± 0.074	1.601AlaTrp: 1.601 ± 0.038	2.168AlaTyr: 2.168 ± 0.038	0.0AlaXaa: 0.0 ± 0.0
Cys	0.947CysAla: 0.947 ± 0.032	0.241CysCys: 0.241 ± 0.014	0.694CysAsp: 0.694 ± 0.026	0.567CysGlu: 0.567 ± 0.024	0.4CysPhe: 0.4 ± 0.018	1.045CysGly: 1.045 ± 0.033	0.305CysHis: 0.305 ± 0.016	0.497CysIle: 0.497 ± 0.02	0.282CysLys: 0.282 ± 0.015	0.958CysLeu: 0.958 ± 0.025	0.278CysMet: 0.278 ± 0.015	0.323CysAsn: 0.323 ± 0.018	0.527CysPro: 0.527 ± 0.022	0.471CysGln: 0.471 ± 0.021	0.648CysArg: 0.648 ± 0.021	0.723CysSer: 0.723 ± 0.025	0.431CysThr: 0.431 ± 0.017	0.664CysVal: 0.664 ± 0.024	0.176CysTrp: 0.176 ± 0.011	0.314CysTyr: 0.314 ± 0.017	0.0CysXaa: 0.0 ± 0.0
Asp	5.644AspAla: 5.644 ± 0.072	0.518AspCys: 0.518 ± 0.022	3.149AspAsp: 3.149 ± 0.062	3.59AspGlu: 3.59 ± 0.055	2.072AspPhe: 2.072 ± 0.043	3.831AspGly: 3.831 ± 0.062	1.109AspHis: 1.109 ± 0.028	3.319AspIle: 3.319 ± 0.046	2.37AspLys: 2.37 ± 0.053	4.663AspLeu: 4.663 ± 0.073	1.394AspMet: 1.394 ± 0.036	2.138AspAsn: 2.138 ± 0.043	2.267AspPro: 2.267 ± 0.041	1.801AspGln: 1.801 ± 0.041	3.002AspArg: 3.002 ± 0.054	2.987AspSer: 2.987 ± 0.048	2.615AspThr: 2.615 ± 0.044	4.005AspVal: 4.005 ± 0.058	0.961AspTrp: 0.961 ± 0.027	1.826AspTyr: 1.826 ± 0.043	0.0AspXaa: 0.0 ± 0.0
Glu	5.697GluAla: 5.697 ± 0.077	0.428GluCys: 0.428 ± 0.018	2.299GluAsp: 2.299 ± 0.042	3.045GluGlu: 3.045 ± 0.065	1.627GluPhe: 1.627 ± 0.039	3.383GluGly: 3.383 ± 0.06	1.382GluHis: 1.382 ± 0.034	3.227GluIle: 3.227 ± 0.058	3.123GluLys: 3.123 ± 0.058	5.535GluLeu: 5.535 ± 0.08	1.757GluMet: 1.757 ± 0.034	2.331GluAsn: 2.331 ± 0.053	2.133GluPro: 2.133 ± 0.042	3.512GluGln: 3.512 ± 0.06	3.703GluArg: 3.703 ± 0.051	2.822GluSer: 2.822 ± 0.044	3.098GluThr: 3.098 ± 0.053	3.494GluVal: 3.494 ± 0.059	0.734GluTrp: 0.734 ± 0.027	1.334GluTyr: 1.334 ± 0.034	0.0GluXaa: 0.0 ± 0.0
Phe	3.587PheAla: 3.587 ± 0.066	0.515PheCys: 0.515 ± 0.021	2.276PheAsp: 2.276 ± 0.039	1.615PheGlu: 1.615 ± 0.034	1.522PhePhe: 1.522 ± 0.046	3.017PheGly: 3.017 ± 0.059	0.784PheHis: 0.784 ± 0.026	2.312PheIle: 2.312 ± 0.048	1.243PheLys: 1.243 ± 0.034	3.119PheLeu: 3.119 ± 0.053	0.973PheMet: 0.973 ± 0.025	1.592PheAsn: 1.592 ± 0.043	1.534PhePro: 1.534 ± 0.036	1.238PheGln: 1.238 ± 0.031	1.949PheArg: 1.949 ± 0.041	2.918PheSer: 2.918 ± 0.054	2.272PheThr: 2.272 ± 0.047	2.346PheVal: 2.346 ± 0.046	0.577PheTrp: 0.577 ± 0.025	1.13PheTyr: 1.13 ± 0.033	0.0PheXaa: 0.0 ± 0.0
Gly	6.225GlyAla: 6.225 ± 0.079	0.982GlyCys: 0.982 ± 0.029	3.704GlyAsp: 3.704 ± 0.065	4.504GlyGlu: 4.504 ± 0.08	3.132GlyPhe: 3.132 ± 0.051	5.269GlyGly: 5.269 ± 0.082	1.658GlyHis: 1.658 ± 0.037	4.759GlyIle: 4.759 ± 0.066	3.973GlyLys: 3.973 ± 0.062	7.317GlyLeu: 7.317 ± 0.084	2.287GlyMet: 2.287 ± 0.044	2.649GlyAsn: 2.649 ± 0.048	2.01GlyPro: 2.01 ± 0.036	2.98GlyGln: 2.98 ± 0.057	4.101GlyArg: 4.101 ± 0.062	4.254GlySer: 4.254 ± 0.062	3.717GlyThr: 3.717 ± 0.06	5.529GlyVal: 5.529 ± 0.068	1.34GlyTrp: 1.34 ± 0.035	2.5GlyTyr: 2.5 ± 0.044	0.0GlyXaa: 0.0 ± 0.0
His	2.162HisAla: 2.162 ± 0.042	0.342HisCys: 0.342 ± 0.017	1.354HisAsp: 1.354 ± 0.037	1.083HisGlu: 1.083 ± 0.03	1.051HisPhe: 1.051 ± 0.031	1.705HisGly: 1.705 ± 0.038	0.793HisHis: 0.793 ± 0.025	1.366HisIle: 1.366 ± 0.028	0.811HisLys: 0.811 ± 0.026	2.41HisLeu: 2.41 ± 0.043	0.543HisMet: 0.543 ± 0.019	0.805HisAsn: 0.805 ± 0.027	1.42HisPro: 1.42 ± 0.03	1.288HisGln: 1.288 ± 0.033	1.355HisArg: 1.355 ± 0.033	1.332HisSer: 1.332 ± 0.032	1.126HisThr: 1.126 ± 0.029	1.278HisVal: 1.278 ± 0.033	0.431HisTrp: 0.431 ± 0.019	0.919HisTyr: 0.919 ± 0.026	0.0HisXaa: 0.0 ± 0.0
Ile	6.229IleAla: 6.229 ± 0.072	0.619IleCys: 0.619 ± 0.023	3.384IleAsp: 3.384 ± 0.053	3.153IleGlu: 3.153 ± 0.053	1.665IlePhe: 1.665 ± 0.044	4.218IleGly: 4.218 ± 0.06	1.2IleHis: 1.2 ± 0.032	2.974IleIle: 2.974 ± 0.06	2.261IleLys: 2.261 ± 0.044	4.553IleLeu: 4.553 ± 0.065	1.239IleMet: 1.239 ± 0.035	2.467IleAsn: 2.467 ± 0.051	2.531IlePro: 2.531 ± 0.044	1.95IleGln: 1.95 ± 0.036	3.061IleArg: 3.061 ± 0.051	3.609IleSer: 3.609 ± 0.056	3.646IleThr: 3.646 ± 0.049	3.762IleVal: 3.762 ± 0.062	0.642IleTrp: 0.642 ± 0.026	1.451IleTyr: 1.451 ± 0.031	0.0IleXaa: 0.0 ± 0.0
Lys	4.297LysAla: 4.297 ± 0.07	0.254LysCys: 0.254 ± 0.015	1.954LysAsp: 1.954 ± 0.043	2.141LysGlu: 2.141 ± 0.048	1.064LysPhe: 1.064 ± 0.029	2.886LysGly: 2.886 ± 0.056	0.922LysHis: 0.922 ± 0.028	2.168LysIle: 2.168 ± 0.04	2.203LysLys: 2.203 ± 0.048	4.04LysLeu: 4.04 ± 0.056	1.253LysMet: 1.253 ± 0.036	1.665LysAsn: 1.665 ± 0.041	2.229LysPro: 2.229 ± 0.047	2.085LysGln: 2.085 ± 0.038	2.64LysArg: 2.64 ± 0.047	2.324LysSer: 2.324 ± 0.05	2.526LysThr: 2.526 ± 0.045	2.891LysVal: 2.891 ± 0.054	0.449LysTrp: 0.449 ± 0.017	1.021LysTyr: 1.021 ± 0.031	0.0LysXaa: 0.0 ± 0.0
Leu	11.514LeuAla: 11.514 ± 0.108	1.189LeuCys: 1.189 ± 0.032	5.34LeuAsp: 5.34 ± 0.074	5.181LeuGlu: 5.181 ± 0.071	4.034LeuPhe: 4.034 ± 0.067	6.92LeuGly: 6.92 ± 0.082	2.388LeuHis: 2.388 ± 0.049	5.733LeuIle: 5.733 ± 0.069	4.537LeuLys: 4.537 ± 0.055	11.84LeuLeu: 11.84 ± 0.128	3.081LeuMet: 3.081 ± 0.058	4.277LeuAsn: 4.277 ± 0.061	5.911LeuPro: 5.911 ± 0.078	4.613LeuGln: 4.613 ± 0.063	6.72LeuArg: 6.72 ± 0.086	7.566LeuSer: 7.566 ± 0.079	6.563LeuThr: 6.563 ± 0.078	6.779LeuVal: 6.779 ± 0.085	1.413LeuTrp: 1.413 ± 0.034	2.64LeuTyr: 2.64 ± 0.052	0.0LeuXaa: 0.0 ± 0.0
Met	3.086MetAla: 3.086 ± 0.05	0.179MetCys: 0.179 ± 0.011	1.264MetAsp: 1.264 ± 0.034	1.139MetGlu: 1.139 ± 0.028	0.818MetPhe: 0.818 ± 0.024	1.764MetGly: 1.764 ± 0.035	0.535MetHis: 0.535 ± 0.021	1.421MetIle: 1.421 ± 0.038	1.421MetLys: 1.421 ± 0.034	3.107MetLeu: 3.107 ± 0.052	0.862MetMet: 0.862 ± 0.033	1.094MetAsn: 1.094 ± 0.03	1.399MetPro: 1.399 ± 0.036	1.373MetGln: 1.373 ± 0.035	1.584MetArg: 1.584 ± 0.035	1.864MetSer: 1.864 ± 0.038	1.788MetThr: 1.788 ± 0.036	1.856MetVal: 1.856 ± 0.042	0.254MetTrp: 0.254 ± 0.013	0.446MetTyr: 0.446 ± 0.019	0.0MetXaa: 0.0 ± 0.0
Asn	3.832AsnAla: 3.832 ± 0.057	0.312AsnCys: 0.312 ± 0.016	2.017AsnAsp: 2.017 ± 0.043	1.717AsnGlu: 1.717 ± 0.038	1.236AsnPhe: 1.236 ± 0.03	3.027AsnGly: 3.027 ± 0.057	0.839AsnHis: 0.839 ± 0.027	2.031AsnIle: 2.031 ± 0.036	1.421AsnLys: 1.421 ± 0.033	3.487AsnLeu: 3.487 ± 0.064	0.824AsnMet: 0.824 ± 0.023	1.534AsnAsn: 1.534 ± 0.039	2.012AsnPro: 2.012 ± 0.043	1.569AsnGln: 1.569 ± 0.034	2.147AsnArg: 2.147 ± 0.041	1.932AsnSer: 1.932 ± 0.045	1.948AsnThr: 1.948 ± 0.042	2.476AsnVal: 2.476 ± 0.044	0.67AsnTrp: 0.67 ± 0.027	1.04AsnTyr: 1.04 ± 0.028	0.0AsnXaa: 0.0 ± 0.0
Pro	5.05ProAla: 5.05 ± 0.072	0.378ProCys: 0.378 ± 0.019	3.108ProAsp: 3.108 ± 0.048	3.191ProGlu: 3.191 ± 0.053	1.727ProPhe: 1.727 ± 0.038	3.648ProGly: 3.648 ± 0.053	1.149ProHis: 1.149 ± 0.026	1.606ProIle: 1.606 ± 0.037	1.447ProLys: 1.447 ± 0.039	5.119ProLeu: 5.119 ± 0.065	1.038ProMet: 1.038 ± 0.029	1.18ProAsn: 1.18 ± 0.03	1.744ProPro: 1.744 ± 0.04	2.185ProGln: 2.185 ± 0.041	2.078ProArg: 2.078 ± 0.034	2.259ProSer: 2.259 ± 0.042	2.116ProThr: 2.116 ± 0.036	4.271ProVal: 4.271 ± 0.061	0.742ProTrp: 0.742 ± 0.024	1.123ProTyr: 1.123 ± 0.028	0.0ProXaa: 0.0 ± 0.0
Gln	5.156GlnAla: 5.156 ± 0.073	0.381GlnCys: 0.381 ± 0.017	1.966GlnAsp: 1.966 ± 0.037	2.092GlnGlu: 2.092 ± 0.044	1.509GlnPhe: 1.509 ± 0.032	3.249GlnGly: 3.249 ± 0.054	1.473GlnHis: 1.473 ± 0.036	2.187GlnIle: 2.187 ± 0.04	1.757GlnLys: 1.757 ± 0.036	5.271GlnLeu: 5.271 ± 0.079	1.292GlnMet: 1.292 ± 0.032	1.516GlnAsn: 1.516 ± 0.036	2.53GlnPro: 2.53 ± 0.049	3.864GlnGln: 3.864 ± 0.083	3.683GlnArg: 3.683 ± 0.067	2.476GlnSer: 2.476 ± 0.044	2.433GlnThr: 2.433 ± 0.046	3.219GlnVal: 3.219 ± 0.055	0.673GlnTrp: 0.673 ± 0.023	1.146GlnTyr: 1.146 ± 0.03	0.0GlnXaa: 0.0 ± 0.0
Arg	5.163ArgAla: 5.163 ± 0.06	0.63ArgCys: 0.63 ± 0.021	3.37ArgAsp: 3.37 ± 0.057	3.855ArgGlu: 3.855 ± 0.065	2.625ArgPhe: 2.625 ± 0.042	3.591ArgGly: 3.591 ± 0.055	1.813ArgHis: 1.813 ± 0.04	3.524ArgIle: 3.524 ± 0.053	2.563ArgLys: 2.563 ± 0.053	6.98ArgLeu: 6.98 ± 0.08	1.631ArgMet: 1.631 ± 0.033	2.069ArgAsn: 2.069 ± 0.041	2.391ArgPro: 2.391 ± 0.045	3.563ArgGln: 3.563 ± 0.065	4.026ArgArg: 4.026 ± 0.065	2.992ArgSer: 2.992 ± 0.047	2.762ArgThr: 2.762 ± 0.05	3.971ArgVal: 3.971 ± 0.056	1.139ArgTrp: 1.139 ± 0.035	2.168ArgTyr: 2.168 ± 0.043	0.0ArgXaa: 0.0 ± 0.0
Ser	6.095SerAla: 6.095 ± 0.078	0.541SerCys: 0.541 ± 0.021	3.317SerAsp: 3.317 ± 0.055	3.403SerGlu: 3.403 ± 0.062	2.14SerPhe: 2.14 ± 0.043	5.348SerGly: 5.348 ± 0.066	1.482SerHis: 1.482 ± 0.035	2.621SerIle: 2.621 ± 0.05	2.0SerLys: 2.0 ± 0.042	6.919SerLeu: 6.919 ± 0.073	1.538SerMet: 1.538 ± 0.033	1.839SerAsn: 1.839 ± 0.042	2.824SerPro: 2.824 ± 0.043	2.798SerGln: 2.798 ± 0.049	3.723SerArg: 3.723 ± 0.058	3.69SerSer: 3.69 ± 0.051	2.917SerThr: 2.917 ± 0.057	4.38SerVal: 4.38 ± 0.066	0.95SerTrp: 0.95 ± 0.027	1.559SerTyr: 1.559 ± 0.039	0.0SerXaa: 0.0 ± 0.0
Thr	5.346ThrAla: 5.346 ± 0.07	0.544ThrCys: 0.544 ± 0.022	2.871ThrAsp: 2.871 ± 0.05	2.665ThrGlu: 2.665 ± 0.05	1.966ThrPhe: 1.966 ± 0.039	4.611ThrGly: 4.611 ± 0.072	1.222ThrHis: 1.222 ± 0.035	2.787ThrIle: 2.787 ± 0.051	1.491ThrLys: 1.491 ± 0.036	7.665ThrLeu: 7.665 ± 0.082	1.084ThrMet: 1.084 ± 0.027	1.433ThrAsn: 1.433 ± 0.037	3.036ThrPro: 3.036 ± 0.054	2.393ThrGln: 2.393 ± 0.045	3.172ThrArg: 3.172 ± 0.053	3.026ThrSer: 3.026 ± 0.05	2.944ThrThr: 2.944 ± 0.068	3.996ThrVal: 3.996 ± 0.093	0.795ThrTrp: 0.795 ± 0.028	1.146ThrTyr: 1.146 ± 0.032	0.0ThrXaa: 0.0 ± 0.0
Val	7.099ValAla: 7.099 ± 0.074	0.675ValCys: 0.675 ± 0.022	3.717ValAsp: 3.717 ± 0.057	3.823ValGlu: 3.823 ± 0.056	2.46ValPhe: 2.46 ± 0.049	4.481ValGly: 4.481 ± 0.079	1.352ValHis: 1.352 ± 0.035	4.39ValIle: 4.39 ± 0.069	3.01ValLys: 3.01 ± 0.061	7.295ValLeu: 7.295 ± 0.074	2.165ValMet: 2.165 ± 0.042	2.797ValAsn: 2.797 ± 0.053	2.991ValPro: 2.991 ± 0.047	2.567ValGln: 2.567 ± 0.044	3.894ValArg: 3.894 ± 0.052	4.705ValSer: 4.705 ± 0.06	4.522ValThr: 4.522 ± 0.08	5.207ValVal: 5.207 ± 0.067	0.98ValTrp: 0.98 ± 0.028	1.636ValTyr: 1.636 ± 0.038	0.0ValXaa: 0.0 ± 0.0
Trp	1.012TrpAla: 1.012 ± 0.026	0.197TrpCys: 0.197 ± 0.012	0.663TrpAsp: 0.663 ± 0.021	0.535TrpGlu: 0.535 ± 0.019	0.7TrpPhe: 0.7 ± 0.024	0.864TrpGly: 0.864 ± 0.028	0.487TrpHis: 0.487 ± 0.021	0.752TrpIle: 0.752 ± 0.025	0.545TrpLys: 0.545 ± 0.021	2.393TrpLeu: 2.393 ± 0.049	0.403TrpMet: 0.403 ± 0.018	0.467TrpAsn: 0.467 ± 0.024	0.739TrpPro: 0.739 ± 0.024	1.328TrpGln: 1.328 ± 0.035	1.097TrpArg: 1.097 ± 0.031	0.867TrpSer: 0.867 ± 0.029	0.554TrpThr: 0.554 ± 0.022	0.929TrpVal: 0.929 ± 0.026	0.228TrpTrp: 0.228 ± 0.013	0.41TrpTyr: 0.41 ± 0.018	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.453TyrAla: 2.453 ± 0.054	0.399TyrCys: 0.399 ± 0.017	1.533TyrAsp: 1.533 ± 0.037	1.146TyrGlu: 1.146 ± 0.03	1.019TyrPhe: 1.019 ± 0.028	2.09TyrGly: 2.09 ± 0.044	0.744TyrHis: 0.744 ± 0.023	1.245TyrIle: 1.245 ± 0.03	0.865TyrLys: 0.865 ± 0.027	2.899TyrLeu: 2.899 ± 0.051	0.551TyrMet: 0.551 ± 0.021	0.979TyrAsn: 0.979 ± 0.027	1.287TyrPro: 1.287 ± 0.027	1.573TyrGln: 1.573 ± 0.033	1.93TyrArg: 1.93 ± 0.038	1.728TyrSer: 1.728 ± 0.033	1.333TyrThr: 1.333 ± 0.029	1.792TyrVal: 1.792 ± 0.045	0.414TyrTrp: 0.414 ± 0.017	0.822TyrTyr: 0.822 ± 0.028	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4581 proteins (1321671 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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