Amino acid dipepetide frequency for Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) (Glume blotch fungus) (Parastagonospora nodorum)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
9.131AlaAla: 9.131 ± 0.055
1.136AlaCys: 1.136 ± 0.014
4.39AlaAsp: 4.39 ± 0.027
5.253AlaGlu: 5.253 ± 0.043
3.245AlaPhe: 3.245 ± 0.026
5.832AlaGly: 5.832 ± 0.041
2.016AlaHis: 2.016 ± 0.018
4.362AlaIle: 4.362 ± 0.03
4.517AlaLys: 4.517 ± 0.03
7.753AlaLeu: 7.753 ± 0.05
2.16AlaMet: 2.16 ± 0.021
3.29AlaAsn: 3.29 ± 0.026
5.266AlaPro: 5.266 ± 0.043
3.726AlaGln: 3.726 ± 0.03
5.072AlaArg: 5.072 ± 0.031
7.377AlaSer: 7.377 ± 0.048
5.5AlaThr: 5.5 ± 0.034
5.375AlaVal: 5.375 ± 0.034
1.24AlaTrp: 1.24 ± 0.016
2.256AlaTyr: 2.256 ± 0.017
0.0AlaXaa: 0.0 ± 0.0
Cys
1.06CysAla: 1.06 ± 0.014
0.268CysCys: 0.268 ± 0.008
0.696CysAsp: 0.696 ± 0.012
0.639CysGlu: 0.639 ± 0.011
0.54CysPhe: 0.54 ± 0.009
0.987CysGly: 0.987 ± 0.015
0.335CysHis: 0.335 ± 0.008
0.751CysIle: 0.751 ± 0.012
0.572CysLys: 0.572 ± 0.009
1.181CysLeu: 1.181 ± 0.016
0.312CysMet: 0.312 ± 0.007
0.461CysAsn: 0.461 ± 0.009
0.685CysPro: 0.685 ± 0.012
0.447CysGln: 0.447 ± 0.008
0.771CysArg: 0.771 ± 0.013
0.942CysSer: 0.942 ± 0.013
0.765CysThr: 0.765 ± 0.013
0.792CysVal: 0.792 ± 0.012
0.209CysTrp: 0.209 ± 0.007
0.368CysTyr: 0.368 ± 0.009
0.0CysXaa: 0.0 ± 0.0
Asp
5.171AspAla: 5.171 ± 0.033
0.659AspCys: 0.659 ± 0.012
4.208AspAsp: 4.208 ± 0.039
4.514AspGlu: 4.514 ± 0.035
2.295AspPhe: 2.295 ± 0.021
4.006AspGly: 4.006 ± 0.028
1.243AspHis: 1.243 ± 0.015
3.033AspIle: 3.033 ± 0.025
2.529AspLys: 2.529 ± 0.023
4.919AspLeu: 4.919 ± 0.036
1.476AspMet: 1.476 ± 0.015
1.845AspAsn: 1.845 ± 0.017
3.139AspPro: 3.139 ± 0.025
1.85AspGln: 1.85 ± 0.019
2.938AspArg: 2.938 ± 0.029
3.929AspSer: 3.929 ± 0.03
3.085AspThr: 3.085 ± 0.027
3.876AspVal: 3.876 ± 0.032
0.962AspTrp: 0.962 ± 0.013
1.612AspTyr: 1.612 ± 0.019
0.0AspXaa: 0.0 ± 0.0
Glu
5.537GluAla: 5.537 ± 0.04
0.668GluCys: 0.668 ± 0.011
4.381GluAsp: 4.381 ± 0.038
5.505GluGlu: 5.505 ± 0.043
1.906GluPhe: 1.906 ± 0.018
3.892GluGly: 3.892 ± 0.027
1.543GluHis: 1.543 ± 0.017
2.92GluIle: 2.92 ± 0.022
3.872GluLys: 3.872 ± 0.029
5.21GluLeu: 5.21 ± 0.034
1.542GluMet: 1.542 ± 0.016
2.175GluAsn: 2.175 ± 0.021
2.721GluPro: 2.721 ± 0.034
2.684GluGln: 2.684 ± 0.024
3.933GluArg: 3.933 ± 0.03
3.939GluSer: 3.939 ± 0.031
3.331GluThr: 3.331 ± 0.025
3.716GluVal: 3.716 ± 0.028
0.923GluTrp: 0.923 ± 0.013
1.701GluTyr: 1.701 ± 0.018
0.0GluXaa: 0.0 ± 0.0
Phe
3.283PheAla: 3.283 ± 0.028
0.569PheCys: 0.569 ± 0.011
2.334PheAsp: 2.334 ± 0.021
2.235PheGlu: 2.235 ± 0.022
1.586PhePhe: 1.586 ± 0.019
2.867PheGly: 2.867 ± 0.028
0.869PheHis: 0.869 ± 0.011
1.745PheIle: 1.745 ± 0.02
1.628PheLys: 1.628 ± 0.018
3.255PheLeu: 3.255 ± 0.029
0.826PheMet: 0.826 ± 0.012
1.459PheAsn: 1.459 ± 0.015
1.892PhePro: 1.892 ± 0.016
1.38PheGln: 1.38 ± 0.015
1.921PheArg: 1.921 ± 0.019
2.877PheSer: 2.877 ± 0.024
2.245PheThr: 2.245 ± 0.021
2.386PheVal: 2.386 ± 0.022
0.636PheTrp: 0.636 ± 0.011
1.066PheTyr: 1.066 ± 0.015
0.0PheXaa: 0.0 ± 0.0
Gly
5.512GlyAla: 5.512 ± 0.035
0.917GlyCys: 0.917 ± 0.014
3.538GlyAsp: 3.538 ± 0.028
3.71GlyGlu: 3.71 ± 0.029
2.757GlyPhe: 2.757 ± 0.026
5.731GlyGly: 5.731 ± 0.062
1.648GlyHis: 1.648 ± 0.021
3.411GlyIle: 3.411 ± 0.029
3.684GlyLys: 3.684 ± 0.028
5.769GlyLeu: 5.769 ± 0.037
1.742GlyMet: 1.742 ± 0.022
2.488GlyAsn: 2.488 ± 0.023
3.108GlyPro: 3.108 ± 0.026
2.522GlyGln: 2.522 ± 0.026
3.995GlyArg: 3.995 ± 0.03
5.334GlySer: 5.334 ± 0.036
3.979GlyThr: 3.979 ± 0.031
4.292GlyVal: 4.292 ± 0.032
1.21GlyTrp: 1.21 ± 0.015
2.119GlyTyr: 2.119 ± 0.022
0.0GlyXaa: 0.0 ± 0.0
His
2.066HisAla: 2.066 ± 0.018
0.368HisCys: 0.368 ± 0.008
1.434HisAsp: 1.434 ± 0.016
1.419HisGlu: 1.419 ± 0.017
0.967HisPhe: 0.967 ± 0.013
1.707HisGly: 1.707 ± 0.016
0.86HisHis: 0.86 ± 0.013
1.258HisIle: 1.258 ± 0.016
1.002HisLys: 1.002 ± 0.013
2.222HisLeu: 2.222 ± 0.02
0.566HisMet: 0.566 ± 0.01
0.903HisAsn: 0.903 ± 0.014
1.614HisPro: 1.614 ± 0.017
0.998HisGln: 0.998 ± 0.013
1.478HisArg: 1.478 ± 0.016
1.8HisSer: 1.8 ± 0.017
1.393HisThr: 1.393 ± 0.015
1.563HisVal: 1.563 ± 0.014
0.36HisTrp: 0.36 ± 0.008
0.703HisTyr: 0.703 ± 0.012
0.0HisXaa: 0.0 ± 0.0
Ile
4.455IleAla: 4.455 ± 0.029
0.753IleCys: 0.753 ± 0.011
2.925IleAsp: 2.925 ± 0.022
2.979IleGlu: 2.979 ± 0.025
1.959IlePhe: 1.959 ± 0.019
3.162IleGly: 3.162 ± 0.028
1.148IleHis: 1.148 ± 0.014
2.458IleIle: 2.458 ± 0.024
2.281IleLys: 2.281 ± 0.021
4.31IleLeu: 4.31 ± 0.034
1.096IleMet: 1.096 ± 0.011
1.815IleAsn: 1.815 ± 0.02
2.88IlePro: 2.88 ± 0.023
1.823IleGln: 1.823 ± 0.016
2.691IleArg: 2.691 ± 0.024
3.677IleSer: 3.677 ± 0.028
2.953IleThr: 2.953 ± 0.023
3.217IleVal: 3.217 ± 0.031
0.738IleTrp: 0.738 ± 0.01
1.365IleTyr: 1.365 ± 0.016
0.0IleXaa: 0.0 ± 0.0
Lys
4.535LysAla: 4.535 ± 0.033
0.546LysCys: 0.546 ± 0.009
3.108LysAsp: 3.108 ± 0.023
3.626LysGlu: 3.626 ± 0.031
1.541LysPhe: 1.541 ± 0.017
3.169LysGly: 3.169 ± 0.027
1.277LysHis: 1.277 ± 0.016
2.362LysIle: 2.362 ± 0.02
3.801LysLys: 3.801 ± 0.053
4.229LysLeu: 4.229 ± 0.027
1.138LysMet: 1.138 ± 0.014
1.862LysAsn: 1.862 ± 0.023
2.831LysPro: 2.831 ± 0.028
2.017LysGln: 2.017 ± 0.021
3.555LysArg: 3.555 ± 0.029
3.606LysSer: 3.606 ± 0.028
3.022LysThr: 3.022 ± 0.024
2.904LysVal: 2.904 ± 0.029
0.747LysTrp: 0.747 ± 0.011
1.437LysTyr: 1.437 ± 0.016
0.0LysXaa: 0.0 ± 0.0
Leu
7.647LeuAla: 7.647 ± 0.046
1.201LeuCys: 1.201 ± 0.016
5.026LeuAsp: 5.026 ± 0.033
5.392LeuGlu: 5.392 ± 0.037
3.186LeuPhe: 3.186 ± 0.03
5.625LeuGly: 5.625 ± 0.034
2.277LeuHis: 2.277 ± 0.021
3.741LeuIle: 3.741 ± 0.028
4.315LeuLys: 4.315 ± 0.031
7.852LeuLeu: 7.852 ± 0.052
1.783LeuMet: 1.783 ± 0.015
3.115LeuAsn: 3.115 ± 0.021
5.522LeuPro: 5.522 ± 0.059
3.791LeuGln: 3.791 ± 0.029
5.56LeuArg: 5.56 ± 0.036
6.835LeuSer: 6.835 ± 0.051
4.703LeuThr: 4.703 ± 0.032
5.193LeuVal: 5.193 ± 0.033
1.179LeuTrp: 1.179 ± 0.016
2.256LeuTyr: 2.256 ± 0.019
0.0LeuXaa: 0.0 ± 0.0
Met
2.336MetAla: 2.336 ± 0.022
0.297MetCys: 0.297 ± 0.006
1.299MetAsp: 1.299 ± 0.016
1.318MetGlu: 1.318 ± 0.016
0.837MetPhe: 0.837 ± 0.013
1.529MetGly: 1.529 ± 0.018
0.582MetHis: 0.582 ± 0.01
1.02MetIle: 1.02 ± 0.013
1.129MetLys: 1.129 ± 0.015
1.988MetLeu: 1.988 ± 0.021
0.615MetMet: 0.615 ± 0.011
0.856MetAsn: 0.856 ± 0.012
1.407MetPro: 1.407 ± 0.017
0.983MetGln: 0.983 ± 0.013
1.414MetArg: 1.414 ± 0.015
2.073MetSer: 2.073 ± 0.019
1.372MetThr: 1.372 ± 0.018
1.352MetVal: 1.352 ± 0.016
0.304MetTrp: 0.304 ± 0.008
0.617MetTyr: 0.617 ± 0.01
0.0MetXaa: 0.0 ± 0.0
Asn
3.395AsnAla: 3.395 ± 0.027
0.453AsnCys: 0.453 ± 0.01
2.094AsnAsp: 2.094 ± 0.019
2.03AsnGlu: 2.03 ± 0.02
1.455AsnPhe: 1.455 ± 0.014
3.025AsnGly: 3.025 ± 0.03
0.836AsnHis: 0.836 ± 0.012
2.074AsnIle: 2.074 ± 0.021
1.688AsnLys: 1.688 ± 0.017
3.131AsnLeu: 3.131 ± 0.023
0.925AsnMet: 0.925 ± 0.015
1.555AsnAsn: 1.555 ± 0.019
2.257AsnPro: 2.257 ± 0.02
1.339AsnGln: 1.339 ± 0.015
1.848AsnArg: 1.848 ± 0.019
2.706AsnSer: 2.706 ± 0.023
2.353AsnThr: 2.353 ± 0.022
2.385AsnVal: 2.385 ± 0.023
0.568AsnTrp: 0.568 ± 0.01
1.048AsnTyr: 1.048 ± 0.014
0.0AsnXaa: 0.0 ± 0.0
Pro
5.472ProAla: 5.472 ± 0.043
0.52ProCys: 0.52 ± 0.01
3.019ProAsp: 3.019 ± 0.021
3.686ProGlu: 3.686 ± 0.03
1.983ProPhe: 1.983 ± 0.02
3.698ProGly: 3.698 ± 0.032
1.417ProHis: 1.417 ± 0.016
2.584ProIle: 2.584 ± 0.022
2.841ProLys: 2.841 ± 0.028
4.52ProLeu: 4.52 ± 0.032
1.176ProMet: 1.176 ± 0.015
2.241ProAsn: 2.241 ± 0.019
4.734ProPro: 4.734 ± 0.058
2.475ProGln: 2.475 ± 0.024
3.292ProArg: 3.292 ± 0.027
5.753ProSer: 5.753 ± 0.053
4.155ProThr: 4.155 ± 0.038
3.456ProVal: 3.456 ± 0.029
0.741ProTrp: 0.741 ± 0.011
1.535ProTyr: 1.535 ± 0.016
0.0ProXaa: 0.0 ± 0.0
Gln
3.59GlnAla: 3.59 ± 0.03
0.47GlnCys: 0.47 ± 0.01
2.223GlnAsp: 2.223 ± 0.021
2.449GlnGlu: 2.449 ± 0.026
1.301GlnPhe: 1.301 ± 0.015
2.43GlnGly: 2.43 ± 0.023
1.198GlnHis: 1.198 ± 0.015
1.908GlnIle: 1.908 ± 0.017
2.076GlnLys: 2.076 ± 0.019
3.459GlnLeu: 3.459 ± 0.027
0.943GlnMet: 0.943 ± 0.015
1.586GlnAsn: 1.586 ± 0.019
2.519GlnPro: 2.519 ± 0.026
2.515GlnGln: 2.515 ± 0.042
2.703GlnArg: 2.703 ± 0.027
3.041GlnSer: 3.041 ± 0.024
2.341GlnThr: 2.341 ± 0.023
2.142GlnVal: 2.142 ± 0.019
0.577GlnTrp: 0.577 ± 0.01
1.206GlnTyr: 1.206 ± 0.014
0.0GlnXaa: 0.0 ± 0.0
Arg
4.822ArgAla: 4.822 ± 0.031
0.742ArgCys: 0.742 ± 0.013
3.272ArgAsp: 3.272 ± 0.026
3.681ArgGlu: 3.681 ± 0.031
2.083ArgPhe: 2.083 ± 0.02
3.615ArgGly: 3.615 ± 0.032
1.575ArgHis: 1.575 ± 0.017
2.965ArgIle: 2.965 ± 0.023
3.595ArgLys: 3.595 ± 0.026
5.151ArgLeu: 5.151 ± 0.032
1.438ArgMet: 1.438 ± 0.016
2.324ArgAsn: 2.324 ± 0.022
3.375ArgPro: 3.375 ± 0.025
2.585ArgGln: 2.585 ± 0.022
4.736ArgArg: 4.736 ± 0.04
4.552ArgSer: 4.552 ± 0.028
3.41ArgThr: 3.41 ± 0.024
3.264ArgVal: 3.264 ± 0.025
0.915ArgTrp: 0.915 ± 0.014
1.604ArgTyr: 1.604 ± 0.019
0.0ArgXaa: 0.0 ± 0.0
Ser
6.69SerAla: 6.69 ± 0.041
0.905SerCys: 0.905 ± 0.012
4.14SerAsp: 4.14 ± 0.027
4.023SerGlu: 4.023 ± 0.03
2.937SerPhe: 2.937 ± 0.023
5.216SerGly: 5.216 ± 0.042
1.89SerHis: 1.89 ± 0.018
3.938SerIle: 3.938 ± 0.03
3.832SerLys: 3.832 ± 0.031
6.724SerLeu: 6.724 ± 0.048
1.812SerMet: 1.812 ± 0.02
3.013SerAsn: 3.013 ± 0.025
5.187SerPro: 5.187 ± 0.042
3.099SerGln: 3.099 ± 0.025
4.687SerArg: 4.687 ± 0.034
7.97SerSer: 7.97 ± 0.064
5.573SerThr: 5.573 ± 0.045
4.434SerVal: 4.434 ± 0.031
1.114SerTrp: 1.114 ± 0.017
2.033SerTyr: 2.033 ± 0.02
0.0SerXaa: 0.0 ± 0.0
Thr
5.341ThrAla: 5.341 ± 0.033
0.847ThrCys: 0.847 ± 0.014
2.889ThrAsp: 2.889 ± 0.025
3.149ThrGlu: 3.149 ± 0.029
2.343ThrPhe: 2.343 ± 0.019
3.991ThrGly: 3.991 ± 0.027
1.394ThrHis: 1.394 ± 0.013
3.193ThrIle: 3.193 ± 0.032
2.824ThrLys: 2.824 ± 0.025
5.308ThrLeu: 5.308 ± 0.032
1.289ThrMet: 1.289 ± 0.017
2.207ThrAsn: 2.207 ± 0.021
4.48ThrPro: 4.48 ± 0.039
2.245ThrGln: 2.245 ± 0.025
3.173ThrArg: 3.173 ± 0.027
5.439ThrSer: 5.439 ± 0.041
4.37ThrThr: 4.37 ± 0.041
3.672ThrVal: 3.672 ± 0.031
0.913ThrTrp: 0.913 ± 0.013
1.635ThrTyr: 1.635 ± 0.017
0.0ThrXaa: 0.0 ± 0.0
Val
5.435ValAla: 5.435 ± 0.034
0.82ValCys: 0.82 ± 0.013
3.72ValAsp: 3.72 ± 0.028
4.039ValGlu: 4.039 ± 0.032
2.399ValPhe: 2.399 ± 0.021
4.0ValGly: 4.0 ± 0.032
1.439ValHis: 1.439 ± 0.015
2.798ValIle: 2.798 ± 0.023
3.089ValLys: 3.089 ± 0.026
5.392ValLeu: 5.392 ± 0.039
1.376ValMet: 1.376 ± 0.014
2.156ValAsn: 2.156 ± 0.021
3.563ValPro: 3.563 ± 0.031
2.484ValGln: 2.484 ± 0.021
3.391ValArg: 3.391 ± 0.023
4.339ValSer: 4.339 ± 0.029
3.491ValThr: 3.491 ± 0.03
4.316ValVal: 4.316 ± 0.038
0.878ValTrp: 0.878 ± 0.013
1.714ValTyr: 1.714 ± 0.019
0.0ValXaa: 0.0 ± 0.0
Trp
1.176TrpAla: 1.176 ± 0.017
0.221TrpCys: 0.221 ± 0.005
0.91TrpAsp: 0.91 ± 0.014
0.854TrpGlu: 0.854 ± 0.012
0.548TrpPhe: 0.548 ± 0.01
0.937TrpGly: 0.937 ± 0.015
0.389TrpHis: 0.389 ± 0.008
0.772TrpIle: 0.772 ± 0.012
0.836TrpLys: 0.836 ± 0.011
1.345TrpLeu: 1.345 ± 0.017
0.424TrpMet: 0.424 ± 0.007
0.653TrpAsn: 0.653 ± 0.011
0.641TrpPro: 0.641 ± 0.011
0.597TrpGln: 0.597 ± 0.009
0.972TrpArg: 0.972 ± 0.014
1.106TrpSer: 1.106 ± 0.015
0.956TrpThr: 0.956 ± 0.013
0.879TrpVal: 0.879 ± 0.014
0.279TrpTrp: 0.279 ± 0.007
0.455TrpTyr: 0.455 ± 0.009
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.244TyrAla: 2.244 ± 0.021
0.422TyrCys: 0.422 ± 0.01
1.681TyrAsp: 1.681 ± 0.019
1.602TyrGlu: 1.602 ± 0.018
1.192TyrPhe: 1.192 ± 0.016
2.046TyrGly: 2.046 ± 0.024
0.743TyrHis: 0.743 ± 0.011
1.393TyrIle: 1.393 ± 0.017
1.2TyrLys: 1.2 ± 0.015
2.483TyrLeu: 2.483 ± 0.02
0.688TyrMet: 0.688 ± 0.01
1.161TyrAsn: 1.161 ± 0.015
1.475TyrPro: 1.475 ± 0.02
1.118TyrGln: 1.118 ± 0.015
1.575TyrArg: 1.575 ± 0.016
1.924TyrSer: 1.924 ± 0.022
1.705TyrThr: 1.705 ± 0.019
1.623TyrVal: 1.623 ± 0.02
0.455TyrTrp: 0.455 ± 0.008
0.921TyrTyr: 0.921 ± 0.019
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 15998 proteins (6077303 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski