Amino acid dipepetide frequency for Desulfomonile tiedjei (strain ATCC 49306 / DSM 6799 / DCB-1)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.56AlaAla: 8.56 ± 0.103	1.184AlaCys: 1.184 ± 0.028	4.332AlaAsp: 4.332 ± 0.065	5.453AlaGlu: 5.453 ± 0.056	3.53AlaPhe: 3.53 ± 0.055	6.584AlaGly: 6.584 ± 0.077	1.637AlaHis: 1.637 ± 0.036	5.343AlaIle: 5.343 ± 0.064	3.959AlaLys: 3.959 ± 0.061	9.019AlaLeu: 9.019 ± 0.093	2.29AlaMet: 2.29 ± 0.043	2.439AlaAsn: 2.439 ± 0.042	3.065AlaPro: 3.065 ± 0.055	2.656AlaGln: 2.656 ± 0.047	4.931AlaArg: 4.931 ± 0.061	4.858AlaSer: 4.858 ± 0.063	3.803AlaThr: 3.803 ± 0.059	6.651AlaVal: 6.651 ± 0.073	0.954AlaTrp: 0.954 ± 0.026	2.323AlaTyr: 2.323 ± 0.041	0.0AlaXaa: 0.0 ± 0.0
Cys	1.031CysAla: 1.031 ± 0.027	0.268CysCys: 0.268 ± 0.014	0.62CysAsp: 0.62 ± 0.019	0.683CysGlu: 0.683 ± 0.023	0.568CysPhe: 0.568 ± 0.015	1.359CysGly: 1.359 ± 0.035	0.407CysHis: 0.407 ± 0.023	0.727CysIle: 0.727 ± 0.023	0.562CysLys: 0.562 ± 0.019	1.216CysLeu: 1.216 ± 0.027	0.323CysMet: 0.323 ± 0.015	0.402CysAsn: 0.402 ± 0.016	0.89CysPro: 0.89 ± 0.03	0.341CysGln: 0.341 ± 0.012	0.902CysArg: 0.902 ± 0.023	0.972CysSer: 0.972 ± 0.028	0.672CysThr: 0.672 ± 0.021	0.854CysVal: 0.854 ± 0.024	0.141CysTrp: 0.141 ± 0.01	0.374CysTyr: 0.374 ± 0.016	0.0CysXaa: 0.0 ± 0.0
Asp	4.086AspAla: 4.086 ± 0.06	0.666AspCys: 0.666 ± 0.021	2.601AspAsp: 2.601 ± 0.078	3.55AspGlu: 3.55 ± 0.052	2.513AspPhe: 2.513 ± 0.038	3.719AspGly: 3.719 ± 0.104	1.091AspHis: 1.091 ± 0.027	3.451AspIle: 3.451 ± 0.051	2.471AspLys: 2.471 ± 0.041	6.127AspLeu: 6.127 ± 0.067	1.374AspMet: 1.374 ± 0.029	1.557AspAsn: 1.557 ± 0.048	3.142AspPro: 3.142 ± 0.052	1.609AspGln: 1.609 ± 0.032	3.7AspArg: 3.7 ± 0.05	3.275AspSer: 3.275 ± 0.068	2.58AspThr: 2.58 ± 0.075	3.896AspVal: 3.896 ± 0.059	0.723AspTrp: 0.723 ± 0.026	1.731AspTyr: 1.731 ± 0.034	0.0AspXaa: 0.0 ± 0.0
Glu	5.596GluAla: 5.596 ± 0.066	0.706GluCys: 0.706 ± 0.022	3.325GluAsp: 3.325 ± 0.052	4.737GluGlu: 4.737 ± 0.068	2.582GluPhe: 2.582 ± 0.04	3.99GluGly: 3.99 ± 0.057	1.378GluHis: 1.378 ± 0.028	5.06GluIle: 5.06 ± 0.052	4.562GluLys: 4.562 ± 0.063	6.419GluLeu: 6.419 ± 0.066	1.861GluMet: 1.861 ± 0.034	2.574GluAsn: 2.574 ± 0.037	2.493GluPro: 2.493 ± 0.04	2.475GluGln: 2.475 ± 0.036	4.158GluArg: 4.158 ± 0.054	4.016GluSer: 4.016 ± 0.059	3.51GluThr: 3.51 ± 0.05	4.179GluVal: 4.179 ± 0.052	0.743GluTrp: 0.743 ± 0.019	1.744GluTyr: 1.744 ± 0.036	0.0GluXaa: 0.0 ± 0.0
Phe	3.314PheAla: 3.314 ± 0.056	0.663PheCys: 0.663 ± 0.018	2.432PheAsp: 2.432 ± 0.042	2.32PheGlu: 2.32 ± 0.038	2.215PhePhe: 2.215 ± 0.044	3.539PheGly: 3.539 ± 0.054	1.009PheHis: 1.009 ± 0.025	2.358PheIle: 2.358 ± 0.039	1.729PheLys: 1.729 ± 0.03	4.631PheLeu: 4.631 ± 0.069	1.048PheMet: 1.048 ± 0.026	1.317PheAsn: 1.317 ± 0.03	2.116PhePro: 2.116 ± 0.04	1.422PheGln: 1.422 ± 0.026	2.728PheArg: 2.728 ± 0.04	3.135PheSer: 3.135 ± 0.05	2.318PheThr: 2.318 ± 0.051	3.183PheVal: 3.183 ± 0.05	0.546PheTrp: 0.546 ± 0.018	1.217PheTyr: 1.217 ± 0.027	0.0PheXaa: 0.0 ± 0.0
Gly	5.849GlyAla: 5.849 ± 0.08	1.142GlyCys: 1.142 ± 0.025	3.604GlyAsp: 3.604 ± 0.088	4.231GlyGlu: 4.231 ± 0.06	3.6GlyPhe: 3.6 ± 0.048	5.41GlyGly: 5.41 ± 0.124	1.57GlyHis: 1.57 ± 0.032	5.762GlyIle: 5.762 ± 0.068	4.429GlyLys: 4.429 ± 0.055	7.383GlyLeu: 7.383 ± 0.085	2.261GlyMet: 2.261 ± 0.04	2.75GlyAsn: 2.75 ± 0.087	2.756GlyPro: 2.756 ± 0.049	2.177GlyGln: 2.177 ± 0.041	4.237GlyArg: 4.237 ± 0.048	4.684GlySer: 4.684 ± 0.067	4.586GlyThr: 4.586 ± 0.117	5.118GlyVal: 5.118 ± 0.06	1.038GlyTrp: 1.038 ± 0.03	2.558GlyTyr: 2.558 ± 0.04	0.0GlyXaa: 0.0 ± 0.0
His	1.667HisAla: 1.667 ± 0.032	0.303HisCys: 0.303 ± 0.014	1.11HisAsp: 1.11 ± 0.028	1.347HisGlu: 1.347 ± 0.031	0.951HisPhe: 0.951 ± 0.024	1.665HisGly: 1.665 ± 0.035	0.542HisHis: 0.542 ± 0.018	1.181HisIle: 1.181 ± 0.027	0.824HisLys: 0.824 ± 0.02	2.054HisLeu: 2.054 ± 0.041	0.522HisMet: 0.522 ± 0.019	0.646HisAsn: 0.646 ± 0.021	1.273HisPro: 1.273 ± 0.028	0.575HisGln: 0.575 ± 0.017	1.199HisArg: 1.199 ± 0.027	1.275HisSer: 1.275 ± 0.026	0.969HisThr: 0.969 ± 0.024	1.511HisVal: 1.511 ± 0.028	0.287HisTrp: 0.287 ± 0.014	0.645HisTyr: 0.645 ± 0.018	0.0HisXaa: 0.0 ± 0.0
Ile	5.637IleAla: 5.637 ± 0.07	0.869IleCys: 0.869 ± 0.024	3.453IleAsp: 3.453 ± 0.059	4.08IleGlu: 4.08 ± 0.051	2.624IlePhe: 2.624 ± 0.039	4.868IleGly: 4.868 ± 0.064	1.373IleHis: 1.373 ± 0.026	3.678IleIle: 3.678 ± 0.056	2.802IleLys: 2.802 ± 0.045	6.83IleLeu: 6.83 ± 0.089	1.547IleMet: 1.547 ± 0.032	1.97IleAsn: 1.97 ± 0.035	3.573IlePro: 3.573 ± 0.047	2.083IleGln: 2.083 ± 0.035	4.144IleArg: 4.144 ± 0.052	4.329IleSer: 4.329 ± 0.053	3.435IleThr: 3.435 ± 0.058	5.017IleVal: 5.017 ± 0.065	0.68IleTrp: 0.68 ± 0.023	1.57IleTyr: 1.57 ± 0.031	0.0IleXaa: 0.0 ± 0.0
Lys	4.326LysAla: 4.326 ± 0.05	0.555LysCys: 0.555 ± 0.019	2.884LysAsp: 2.884 ± 0.044	3.795LysGlu: 3.795 ± 0.058	1.601LysPhe: 1.601 ± 0.03	3.651LysGly: 3.651 ± 0.052	0.952LysHis: 0.952 ± 0.025	3.635LysIle: 3.635 ± 0.048	3.479LysLys: 3.479 ± 0.055	4.479LysLeu: 4.479 ± 0.053	1.426LysMet: 1.426 ± 0.031	1.978LysAsn: 1.978 ± 0.039	2.415LysPro: 2.415 ± 0.044	1.711LysGln: 1.711 ± 0.035	3.061LysArg: 3.061 ± 0.041	3.106LysSer: 3.106 ± 0.048	2.897LysThr: 2.897 ± 0.041	3.368LysVal: 3.368 ± 0.053	0.582LysTrp: 0.582 ± 0.021	1.44LysTyr: 1.44 ± 0.028	0.0LysXaa: 0.0 ± 0.0
Leu	8.816LeuAla: 8.816 ± 0.085	1.252LeuCys: 1.252 ± 0.036	5.472LeuAsp: 5.472 ± 0.07	6.794LeuGlu: 6.794 ± 0.067	4.325LeuPhe: 4.325 ± 0.07	7.421LeuGly: 7.421 ± 0.084	1.868LeuHis: 1.868 ± 0.033	6.125LeuIle: 6.125 ± 0.077	5.586LeuLys: 5.586 ± 0.064	9.864LeuLeu: 9.864 ± 0.133	2.634LeuMet: 2.634 ± 0.048	3.553LeuAsn: 3.553 ± 0.06	4.615LeuPro: 4.615 ± 0.053	3.293LeuGln: 3.293 ± 0.046	5.789LeuArg: 5.789 ± 0.063	6.666LeuSer: 6.666 ± 0.073	5.364LeuThr: 5.364 ± 0.066	7.258LeuVal: 7.258 ± 0.084	1.133LeuTrp: 1.133 ± 0.029	2.573LeuTyr: 2.573 ± 0.043	0.0LeuXaa: 0.0 ± 0.0
Met	2.427MetAla: 2.427 ± 0.035	0.291MetCys: 0.291 ± 0.014	1.479MetAsp: 1.479 ± 0.029	1.811MetGlu: 1.811 ± 0.034	0.832MetPhe: 0.832 ± 0.022	2.072MetGly: 2.072 ± 0.036	0.496MetHis: 0.496 ± 0.018	1.644MetIle: 1.644 ± 0.036	1.712MetLys: 1.712 ± 0.029	2.298MetLeu: 2.298 ± 0.039	0.677MetMet: 0.677 ± 0.022	1.132MetAsn: 1.132 ± 0.027	1.195MetPro: 1.195 ± 0.027	0.83MetGln: 0.83 ± 0.022	1.567MetArg: 1.567 ± 0.033	1.592MetSer: 1.592 ± 0.036	1.458MetThr: 1.458 ± 0.031	1.815MetVal: 1.815 ± 0.034	0.247MetTrp: 0.247 ± 0.013	0.585MetTyr: 0.585 ± 0.018	0.0MetXaa: 0.0 ± 0.0
Asn	2.822AsnAla: 2.822 ± 0.053	0.498AsnCys: 0.498 ± 0.018	1.692AsnAsp: 1.692 ± 0.071	1.892AsnGlu: 1.892 ± 0.036	1.302AsnPhe: 1.302 ± 0.029	2.65AsnGly: 2.65 ± 0.083	0.698AsnHis: 0.698 ± 0.021	2.043AsnIle: 2.043 ± 0.034	1.371AsnLys: 1.371 ± 0.033	3.733AsnLeu: 3.733 ± 0.046	0.808AsnMet: 0.808 ± 0.024	1.093AsnAsn: 1.093 ± 0.045	2.381AsnPro: 2.381 ± 0.036	1.084AsnGln: 1.084 ± 0.031	2.266AsnArg: 2.266 ± 0.039	2.034AsnSer: 2.034 ± 0.042	1.665AsnThr: 1.665 ± 0.053	2.492AsnVal: 2.492 ± 0.045	0.465AsnTrp: 0.465 ± 0.019	0.96AsnTyr: 0.96 ± 0.022	0.0AsnXaa: 0.0 ± 0.0
Pro	3.743ProAla: 3.743 ± 0.052	0.547ProCys: 0.547 ± 0.02	3.279ProAsp: 3.279 ± 0.053	4.205ProGlu: 4.205 ± 0.056	2.091ProPhe: 2.091 ± 0.038	3.809ProGly: 3.809 ± 0.045	1.004ProHis: 1.004 ± 0.028	2.544ProIle: 2.544 ± 0.04	2.137ProLys: 2.137 ± 0.045	4.321ProLeu: 4.321 ± 0.052	1.068ProMet: 1.068 ± 0.026	1.465ProAsn: 1.465 ± 0.037	2.283ProPro: 2.283 ± 0.046	1.621ProGln: 1.621 ± 0.033	2.311ProArg: 2.311 ± 0.04	2.786ProSer: 2.786 ± 0.045	2.173ProThr: 2.173 ± 0.038	3.869ProVal: 3.869 ± 0.054	0.587ProTrp: 0.587 ± 0.019	1.424ProTyr: 1.424 ± 0.031	0.0ProXaa: 0.0 ± 0.0
Gln	2.896GlnAla: 2.896 ± 0.045	0.424GlnCys: 0.424 ± 0.017	1.775GlnAsp: 1.775 ± 0.033	2.438GlnGlu: 2.438 ± 0.04	1.232GlnPhe: 1.232 ± 0.031	2.268GlnGly: 2.268 ± 0.041	0.567GlnHis: 0.567 ± 0.018	2.165GlnIle: 2.165 ± 0.036	1.856GlnLys: 1.856 ± 0.037	2.745GlnLeu: 2.745 ± 0.044	0.888GlnMet: 0.888 ± 0.021	1.154GlnAsn: 1.154 ± 0.024	1.34GlnPro: 1.34 ± 0.03	1.233GlnGln: 1.233 ± 0.051	1.872GlnArg: 1.872 ± 0.039	1.968GlnSer: 1.968 ± 0.037	1.695GlnThr: 1.695 ± 0.037	2.388GlnVal: 2.388 ± 0.044	0.441GlnTrp: 0.441 ± 0.016	0.896GlnTyr: 0.896 ± 0.023	0.0GlnXaa: 0.0 ± 0.0
Arg	4.296ArgAla: 4.296 ± 0.057	0.738ArgCys: 0.738 ± 0.023	3.322ArgAsp: 3.322 ± 0.053	4.475ArgGlu: 4.475 ± 0.056	2.804ArgPhe: 2.804 ± 0.043	3.634ArgGly: 3.634 ± 0.052	1.171ArgHis: 1.171 ± 0.028	4.586ArgIle: 4.586 ± 0.057	3.586ArgLys: 3.586 ± 0.05	5.939ArgLeu: 5.939 ± 0.067	1.752ArgMet: 1.752 ± 0.033	2.34ArgAsn: 2.34 ± 0.04	2.512ArgPro: 2.512 ± 0.048	1.991ArgGln: 1.991 ± 0.035	3.54ArgArg: 3.54 ± 0.049	3.801ArgSer: 3.801 ± 0.039	3.15ArgThr: 3.15 ± 0.042	4.156ArgVal: 4.156 ± 0.053	0.717ArgTrp: 0.717 ± 0.022	1.782ArgTyr: 1.782 ± 0.031	0.0ArgXaa: 0.0 ± 0.0
Ser	5.041SerAla: 5.041 ± 0.059	0.897SerCys: 0.897 ± 0.026	3.454SerAsp: 3.454 ± 0.065	4.172SerGlu: 4.172 ± 0.053	2.825SerPhe: 2.825 ± 0.048	5.592SerGly: 5.592 ± 0.064	1.323SerHis: 1.323 ± 0.029	3.908SerIle: 3.908 ± 0.052	2.69SerLys: 2.69 ± 0.044	6.532SerLeu: 6.532 ± 0.063	1.641SerMet: 1.641 ± 0.029	1.848SerAsn: 1.848 ± 0.034	3.064SerPro: 3.064 ± 0.043	2.005SerGln: 2.005 ± 0.033	3.984SerArg: 3.984 ± 0.055	4.099SerSer: 4.099 ± 0.061	2.967SerThr: 2.967 ± 0.051	4.513SerVal: 4.513 ± 0.054	0.858SerTrp: 0.858 ± 0.025	1.681SerTyr: 1.681 ± 0.033	0.0SerXaa: 0.0 ± 0.0
Thr	4.545ThrAla: 4.545 ± 0.053	0.704ThrCys: 0.704 ± 0.022	2.838ThrAsp: 2.838 ± 0.068	3.174ThrGlu: 3.174 ± 0.049	2.241ThrPhe: 2.241 ± 0.046	4.719ThrGly: 4.719 ± 0.075	1.03ThrHis: 1.03 ± 0.026	3.398ThrIle: 3.398 ± 0.065	2.222ThrLys: 2.222 ± 0.04	5.196ThrLeu: 5.196 ± 0.095	1.196ThrMet: 1.196 ± 0.024	1.637ThrAsn: 1.637 ± 0.042	2.614ThrPro: 2.614 ± 0.044	1.439ThrGln: 1.439 ± 0.031	2.905ThrArg: 2.905 ± 0.044	2.988ThrSer: 2.988 ± 0.045	2.552ThrThr: 2.552 ± 0.05	4.214ThrVal: 4.214 ± 0.074	0.645ThrTrp: 0.645 ± 0.022	1.469ThrTyr: 1.469 ± 0.043	0.0ThrXaa: 0.0 ± 0.0
Val	5.915ValAla: 5.915 ± 0.069	1.006ValCys: 1.006 ± 0.024	3.985ValAsp: 3.985 ± 0.06	4.5ValGlu: 4.5 ± 0.045	3.416ValPhe: 3.416 ± 0.046	4.953ValGly: 4.953 ± 0.064	1.534ValHis: 1.534 ± 0.031	4.722ValIle: 4.722 ± 0.054	3.511ValLys: 3.511 ± 0.051	7.521ValLeu: 7.521 ± 0.085	1.807ValMet: 1.807 ± 0.04	2.592ValAsn: 2.592 ± 0.05	3.591ValPro: 3.591 ± 0.049	2.318ValGln: 2.318 ± 0.03	4.392ValArg: 4.392 ± 0.054	4.832ValSer: 4.832 ± 0.058	3.908ValThr: 3.908 ± 0.074	5.43ValVal: 5.43 ± 0.065	0.795ValTrp: 0.795 ± 0.023	1.904ValTyr: 1.904 ± 0.039	0.0ValXaa: 0.0 ± 0.0
Trp	0.903TrpAla: 0.903 ± 0.023	0.152TrpCys: 0.152 ± 0.01	0.672TrpAsp: 0.672 ± 0.025	0.753TrpGlu: 0.753 ± 0.023	0.565TrpPhe: 0.565 ± 0.02	0.843TrpGly: 0.843 ± 0.022	0.251TrpHis: 0.251 ± 0.012	0.874TrpIle: 0.874 ± 0.027	0.715TrpLys: 0.715 ± 0.023	1.182TrpLeu: 1.182 ± 0.031	0.389TrpMet: 0.389 ± 0.013	0.562TrpAsn: 0.562 ± 0.023	0.501TrpPro: 0.501 ± 0.019	0.452TrpGln: 0.452 ± 0.017	0.668TrpArg: 0.668 ± 0.016	0.711TrpSer: 0.711 ± 0.02	0.672TrpThr: 0.672 ± 0.025	0.78TrpVal: 0.78 ± 0.023	0.263TrpTrp: 0.263 ± 0.016	0.358TrpTyr: 0.358 ± 0.018	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.103TyrAla: 2.103 ± 0.036	0.444TyrCys: 0.444 ± 0.018	1.533TyrAsp: 1.533 ± 0.035	1.697TyrGlu: 1.697 ± 0.03	1.422TyrPhe: 1.422 ± 0.034	2.401TyrGly: 2.401 ± 0.055	0.645TyrHis: 0.645 ± 0.02	1.357TyrIle: 1.357 ± 0.029	1.136TyrLys: 1.136 ± 0.026	2.912TyrLeu: 2.912 ± 0.04	0.648TyrMet: 0.648 ± 0.02	0.94TyrAsn: 0.94 ± 0.027	1.448TyrPro: 1.448 ± 0.028	0.929TyrGln: 0.929 ± 0.029	1.939TyrArg: 1.939 ± 0.032	1.966TyrSer: 1.966 ± 0.038	1.352TyrThr: 1.352 ± 0.037	1.945TyrVal: 1.945 ± 0.034	0.419TyrTrp: 0.419 ± 0.016	1.037TyrTyr: 1.037 ± 0.028	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 5412 proteins (1757775 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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