Amino acid dipepetide frequency for Hyella patelloides LEGE 07179

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.312AlaAla: 5.312 ± 0.06	0.713AlaCys: 0.713 ± 0.018	3.554AlaAsp: 3.554 ± 0.049	5.055AlaGlu: 5.055 ± 0.053	2.785AlaPhe: 2.785 ± 0.039	4.58AlaGly: 4.58 ± 0.061	1.144AlaHis: 1.144 ± 0.03	7.128AlaIle: 7.128 ± 0.077	4.366AlaLys: 4.366 ± 0.051	7.347AlaLeu: 7.347 ± 0.066	1.495AlaMet: 1.495 ± 0.032	3.556AlaAsn: 3.556 ± 0.061	2.344AlaPro: 2.344 ± 0.04	3.637AlaGln: 3.637 ± 0.051	3.029AlaArg: 3.029 ± 0.045	4.523AlaSer: 4.523 ± 0.047	4.473AlaThr: 4.473 ± 0.057	4.755AlaVal: 4.755 ± 0.057	0.857AlaTrp: 0.857 ± 0.023	2.292AlaTyr: 2.292 ± 0.035	0.0AlaXaa: 0.0 ± 0.0
Cys	0.553CysAla: 0.553 ± 0.017	0.169CysCys: 0.169 ± 0.009	0.632CysAsp: 0.632 ± 0.021	0.48CysGlu: 0.48 ± 0.016	0.516CysPhe: 0.516 ± 0.017	0.734CysGly: 0.734 ± 0.02	0.301CysHis: 0.301 ± 0.012	0.573CysIle: 0.573 ± 0.019	0.391CysLys: 0.391 ± 0.014	1.277CysLeu: 1.277 ± 0.024	0.154CysMet: 0.154 ± 0.009	0.45CysAsn: 0.45 ± 0.013	0.502CysPro: 0.502 ± 0.018	0.666CysGln: 0.666 ± 0.019	0.519CysArg: 0.519 ± 0.018	0.753CysSer: 0.753 ± 0.021	0.423CysThr: 0.423 ± 0.016	0.506CysVal: 0.506 ± 0.014	0.163CysTrp: 0.163 ± 0.009	0.386CysTyr: 0.386 ± 0.014	0.0CysXaa: 0.0 ± 0.0
Asp	3.204AspAla: 3.204 ± 0.048	0.603AspCys: 0.603 ± 0.016	2.559AspAsp: 2.559 ± 0.059	2.986AspGlu: 2.986 ± 0.041	2.595AspPhe: 2.595 ± 0.042	3.372AspGly: 3.372 ± 0.078	0.562AspHis: 0.562 ± 0.017	3.916AspIle: 3.916 ± 0.05	2.486AspLys: 2.486 ± 0.04	5.915AspLeu: 5.915 ± 0.056	0.703AspMet: 0.703 ± 0.018	2.937AspAsn: 2.937 ± 0.05	1.933AspPro: 1.933 ± 0.032	0.964AspGln: 0.964 ± 0.022	4.194AspArg: 4.194 ± 0.044	3.677AspSer: 3.677 ± 0.048	2.843AspThr: 2.843 ± 0.051	2.864AspVal: 2.864 ± 0.041	0.893AspTrp: 0.893 ± 0.021	2.146AspTyr: 2.146 ± 0.034	0.0AspXaa: 0.0 ± 0.0
Glu	5.105GluAla: 5.105 ± 0.059	0.475GluCys: 0.475 ± 0.016	3.095GluAsp: 3.095 ± 0.05	4.518GluGlu: 4.518 ± 0.062	2.402GluPhe: 2.402 ± 0.036	3.325GluGly: 3.325 ± 0.046	0.971GluHis: 0.971 ± 0.023	5.73GluIle: 5.73 ± 0.051	4.221GluLys: 4.221 ± 0.048	7.108GluLeu: 7.108 ± 0.069	1.257GluMet: 1.257 ± 0.026	3.262GluAsn: 3.262 ± 0.044	2.319GluPro: 2.319 ± 0.037	3.865GluGln: 3.865 ± 0.049	3.036GluArg: 3.036 ± 0.038	3.884GluSer: 3.884 ± 0.049	4.014GluThr: 4.014 ± 0.054	4.067GluVal: 4.067 ± 0.045	0.719GluTrp: 0.719 ± 0.017	2.026GluTyr: 2.026 ± 0.034	0.0GluXaa: 0.0 ± 0.0
Phe	3.115PheAla: 3.115 ± 0.04	0.565PheCys: 0.565 ± 0.016	2.441PheAsp: 2.441 ± 0.041	2.22PheGlu: 2.22 ± 0.039	1.88PhePhe: 1.88 ± 0.034	2.815PheGly: 2.815 ± 0.045	0.708PheHis: 0.708 ± 0.021	2.719PheIle: 2.719 ± 0.039	1.896PheLys: 1.896 ± 0.034	4.401PheLeu: 4.401 ± 0.054	0.709PheMet: 0.709 ± 0.02	2.146PheAsn: 2.146 ± 0.039	1.835PhePro: 1.835 ± 0.035	1.803PheGln: 1.803 ± 0.032	1.789PheArg: 1.789 ± 0.03	3.207PheSer: 3.207 ± 0.044	2.431PheThr: 2.431 ± 0.036	2.394PheVal: 2.394 ± 0.037	0.722PheTrp: 0.722 ± 0.02	1.466PheTyr: 1.466 ± 0.026	0.0PheXaa: 0.0 ± 0.0
Gly	4.159GlyAla: 4.159 ± 0.06	0.732GlyCys: 0.732 ± 0.02	3.436GlyAsp: 3.436 ± 0.072	4.081GlyGlu: 4.081 ± 0.057	2.991GlyPhe: 2.991 ± 0.052	4.522GlyGly: 4.522 ± 0.089	1.047GlyHis: 1.047 ± 0.025	5.3GlyIle: 5.3 ± 0.056	4.145GlyLys: 4.145 ± 0.054	6.134GlyLeu: 6.134 ± 0.063	1.387GlyMet: 1.387 ± 0.028	3.464GlyAsn: 3.464 ± 0.082	0.696GlyPro: 0.696 ± 0.021	2.401GlyGln: 2.401 ± 0.036	2.613GlyArg: 2.613 ± 0.04	3.994GlySer: 3.994 ± 0.057	3.642GlyThr: 3.642 ± 0.058	4.248GlyVal: 4.248 ± 0.049	1.012GlyTrp: 1.012 ± 0.024	2.347GlyTyr: 2.347 ± 0.037	0.0GlyXaa: 0.0 ± 0.0
His	0.817HisAla: 0.817 ± 0.023	0.273HisCys: 0.273 ± 0.011	0.712HisAsp: 0.712 ± 0.02	0.797HisGlu: 0.797 ± 0.021	0.805HisPhe: 0.805 ± 0.022	0.981HisGly: 0.981 ± 0.022	0.612HisHis: 0.612 ± 0.019	1.054HisIle: 1.054 ± 0.022	0.893HisLys: 0.893 ± 0.022	2.11HisLeu: 2.11 ± 0.036	0.218HisMet: 0.218 ± 0.011	0.9HisAsn: 0.9 ± 0.02	1.096HisPro: 1.096 ± 0.021	1.2HisGln: 1.2 ± 0.029	1.004HisArg: 1.004 ± 0.022	1.189HisSer: 1.189 ± 0.022	0.808HisThr: 0.808 ± 0.022	0.644HisVal: 0.644 ± 0.019	0.322HisTrp: 0.322 ± 0.012	0.689HisTyr: 0.689 ± 0.021	0.0HisXaa: 0.0 ± 0.0
Ile	7.482IleAla: 7.482 ± 0.066	0.855IleCys: 0.855 ± 0.023	4.408IleAsp: 4.408 ± 0.055	5.24IleGlu: 5.24 ± 0.058	3.079IlePhe: 3.079 ± 0.047	4.501IleGly: 4.501 ± 0.053	1.184IleHis: 1.184 ± 0.021	5.079IleIle: 5.079 ± 0.064	4.075IleLys: 4.075 ± 0.047	7.307IleLeu: 7.307 ± 0.069	1.042IleMet: 1.042 ± 0.022	3.897IleAsn: 3.897 ± 0.047	3.664IlePro: 3.664 ± 0.047	2.868IleGln: 2.868 ± 0.031	3.088IleArg: 3.088 ± 0.043	5.349IleSer: 5.349 ± 0.052	4.461IleThr: 4.461 ± 0.053	4.683IleVal: 4.683 ± 0.054	0.877IleTrp: 0.877 ± 0.022	2.289IleTyr: 2.289 ± 0.035	0.0IleXaa: 0.0 ± 0.0
Lys	4.211LysAla: 4.211 ± 0.046	0.415LysCys: 0.415 ± 0.016	2.467LysAsp: 2.467 ± 0.045	3.635LysGlu: 3.635 ± 0.056	1.955LysPhe: 1.955 ± 0.033	2.774LysGly: 2.774 ± 0.038	0.962LysHis: 0.962 ± 0.022	4.712LysIle: 4.712 ± 0.055	3.55LysLys: 3.55 ± 0.055	6.156LysLeu: 6.156 ± 0.06	1.139LysMet: 1.139 ± 0.025	2.849LysAsn: 2.849 ± 0.046	2.489LysPro: 2.489 ± 0.034	3.338LysGln: 3.338 ± 0.05	2.515LysArg: 2.515 ± 0.038	3.608LysSer: 3.608 ± 0.045	3.415LysThr: 3.415 ± 0.041	3.433LysVal: 3.433 ± 0.045	0.583LysTrp: 0.583 ± 0.017	1.864LysTyr: 1.864 ± 0.035	0.0LysXaa: 0.0 ± 0.0
Leu	8.886LeuAla: 8.886 ± 0.08	0.979LeuCys: 0.979 ± 0.02	5.61LeuAsp: 5.61 ± 0.061	7.701LeuGlu: 7.701 ± 0.069	4.021LeuPhe: 4.021 ± 0.052	7.188LeuGly: 7.188 ± 0.066	1.657LeuHis: 1.657 ± 0.032	7.737LeuIle: 7.737 ± 0.071	6.309LeuLys: 6.309 ± 0.074	10.899LeuLeu: 10.899 ± 0.113	1.936LeuMet: 1.936 ± 0.03	5.068LeuAsn: 5.068 ± 0.059	4.916LeuPro: 4.916 ± 0.054	5.248LeuGln: 5.248 ± 0.068	4.684LeuArg: 4.684 ± 0.053	7.759LeuSer: 7.759 ± 0.063	6.408LeuThr: 6.408 ± 0.061	6.692LeuVal: 6.692 ± 0.054	1.326LeuTrp: 1.326 ± 0.03	2.793LeuTyr: 2.793 ± 0.038	0.0LeuXaa: 0.0 ± 0.0
Met	1.542MetAla: 1.542 ± 0.029	0.112MetCys: 0.112 ± 0.007	0.702MetAsp: 0.702 ± 0.019	0.966MetGlu: 0.966 ± 0.022	0.608MetPhe: 0.608 ± 0.017	1.305MetGly: 1.305 ± 0.028	0.252MetHis: 0.252 ± 0.012	1.112MetIle: 1.112 ± 0.023	1.105MetLys: 1.105 ± 0.025	1.85MetLeu: 1.85 ± 0.037	0.461MetMet: 0.461 ± 0.018	0.963MetAsn: 0.963 ± 0.023	0.835MetPro: 0.835 ± 0.019	0.733MetGln: 0.733 ± 0.023	0.838MetArg: 0.838 ± 0.022	1.41MetSer: 1.41 ± 0.027	1.256MetThr: 1.256 ± 0.027	1.159MetVal: 1.159 ± 0.027	0.173MetTrp: 0.173 ± 0.009	0.395MetTyr: 0.395 ± 0.013	0.0MetXaa: 0.0 ± 0.0
Asn	2.939AsnAla: 2.939 ± 0.042	0.579AsnCys: 0.579 ± 0.019	2.154AsnAsp: 2.154 ± 0.051	2.1AsnGlu: 2.1 ± 0.033	2.364AsnPhe: 2.364 ± 0.038	2.763AsnGly: 2.763 ± 0.058	1.044AsnHis: 1.044 ± 0.021	3.622AsnIle: 3.622 ± 0.046	2.513AsnLys: 2.513 ± 0.043	6.377AsnLeu: 6.377 ± 0.077	0.796AsnMet: 0.796 ± 0.021	3.182AsnAsn: 3.182 ± 0.055	2.863AsnPro: 2.863 ± 0.038	3.131AsnGln: 3.131 ± 0.041	2.477AsnArg: 2.477 ± 0.032	4.13AsnSer: 4.13 ± 0.061	2.639AsnThr: 2.639 ± 0.04	2.311AsnVal: 2.311 ± 0.041	0.836AsnTrp: 0.836 ± 0.021	2.004AsnTyr: 2.004 ± 0.034	0.0AsnXaa: 0.0 ± 0.0
Pro	2.298ProAla: 2.298 ± 0.035	0.329ProCys: 0.329 ± 0.013	2.612ProAsp: 2.612 ± 0.044	3.689ProGlu: 3.689 ± 0.051	1.634ProPhe: 1.634 ± 0.025	2.431ProGly: 2.431 ± 0.043	0.801ProHis: 0.801 ± 0.022	2.945ProIle: 2.945 ± 0.038	2.12ProLys: 2.12 ± 0.037	4.266ProLeu: 4.266 ± 0.052	0.65ProMet: 0.65 ± 0.018	2.11ProAsn: 2.11 ± 0.036	1.725ProPro: 1.725 ± 0.037	2.521ProGln: 2.521 ± 0.039	1.519ProArg: 1.519 ± 0.034	2.543ProSer: 2.543 ± 0.037	2.334ProThr: 2.334 ± 0.034	2.611ProVal: 2.611 ± 0.036	0.557ProTrp: 0.557 ± 0.018	1.259ProTyr: 1.259 ± 0.024	0.0ProXaa: 0.0 ± 0.0
Gln	3.908GlnAla: 3.908 ± 0.058	0.357GlnCys: 0.357 ± 0.015	2.375GlnAsp: 2.375 ± 0.033	3.898GlnGlu: 3.898 ± 0.052	1.699GlnPhe: 1.699 ± 0.026	2.899GlnGly: 2.899 ± 0.038	0.826GlnHis: 0.826 ± 0.018	3.863GlnIle: 3.863 ± 0.041	3.53GlnLys: 3.53 ± 0.05	5.611GlnLeu: 5.611 ± 0.073	0.901GlnMet: 0.901 ± 0.019	2.404GlnAsn: 2.404 ± 0.038	2.131GlnPro: 2.131 ± 0.04	3.756GlnGln: 3.756 ± 0.066	2.244GlnArg: 2.244 ± 0.038	2.942GlnSer: 2.942 ± 0.047	2.74GlnThr: 2.74 ± 0.042	3.077GlnVal: 3.077 ± 0.045	0.714GlnTrp: 0.714 ± 0.019	1.371GlnTyr: 1.371 ± 0.03	0.0GlnXaa: 0.0 ± 0.0
Arg	2.783ArgAla: 2.783 ± 0.044	0.505ArgCys: 0.505 ± 0.016	2.564ArgAsp: 2.564 ± 0.039	3.217ArgGlu: 3.217 ± 0.041	2.043ArgPhe: 2.043 ± 0.037	2.744ArgGly: 2.744 ± 0.046	0.899ArgHis: 0.899 ± 0.022	3.288ArgIle: 3.288 ± 0.038	2.582ArgLys: 2.582 ± 0.041	5.268ArgLeu: 5.268 ± 0.058	0.86ArgMet: 0.86 ± 0.021	2.246ArgAsn: 2.246 ± 0.036	1.607ArgPro: 1.607 ± 0.029	2.804ArgGln: 2.804 ± 0.042	2.54ArgArg: 2.54 ± 0.051	3.053ArgSer: 3.053 ± 0.036	2.228ArgThr: 2.228 ± 0.031	2.887ArgVal: 2.887 ± 0.039	0.709ArgTrp: 0.709 ± 0.019	1.807ArgTyr: 1.807 ± 0.031	0.0ArgXaa: 0.0 ± 0.0
Ser	4.287SerAla: 4.287 ± 0.042	0.749SerCys: 0.749 ± 0.018	3.678SerAsp: 3.678 ± 0.053	4.218SerGlu: 4.218 ± 0.049	3.075SerPhe: 3.075 ± 0.041	4.452SerGly: 4.452 ± 0.056	1.333SerHis: 1.333 ± 0.027	4.673SerIle: 4.673 ± 0.052	3.304SerLys: 3.304 ± 0.046	8.077SerLeu: 8.077 ± 0.061	1.223SerMet: 1.223 ± 0.025	3.516SerAsn: 3.516 ± 0.048	3.037SerPro: 3.037 ± 0.04	3.948SerGln: 3.948 ± 0.056	3.042SerArg: 3.042 ± 0.04	5.127SerSer: 5.127 ± 0.056	3.573SerThr: 3.573 ± 0.044	3.89SerVal: 3.89 ± 0.055	0.971SerTrp: 0.971 ± 0.025	2.097SerTyr: 2.097 ± 0.03	0.0SerXaa: 0.0 ± 0.0
Thr	4.536ThrAla: 4.536 ± 0.058	0.424ThrCys: 0.424 ± 0.018	2.797ThrAsp: 2.797 ± 0.05	3.911ThrGlu: 3.911 ± 0.051	2.202ThrPhe: 2.202 ± 0.037	3.946ThrGly: 3.946 ± 0.059	0.911ThrHis: 0.911 ± 0.022	4.745ThrIle: 4.745 ± 0.058	3.043ThrLys: 3.043 ± 0.038	5.949ThrLeu: 5.949 ± 0.057	0.857ThrMet: 0.857 ± 0.019	2.8ThrAsn: 2.8 ± 0.038	2.965ThrPro: 2.965 ± 0.04	2.589ThrGln: 2.589 ± 0.037	2.083ThrArg: 2.083 ± 0.033	3.574ThrSer: 3.574 ± 0.046	3.721ThrThr: 3.721 ± 0.056	4.029ThrVal: 4.029 ± 0.054	0.678ThrTrp: 0.678 ± 0.021	1.748ThrTyr: 1.748 ± 0.033	0.0ThrXaa: 0.0 ± 0.0
Val	5.224ValAla: 5.224 ± 0.055	0.654ValCys: 0.654 ± 0.018	3.31ValAsp: 3.31 ± 0.045	4.117ValGlu: 4.117 ± 0.049	2.477ValPhe: 2.477 ± 0.038	4.059ValGly: 4.059 ± 0.049	0.85ValHis: 0.85 ± 0.018	4.474ValIle: 4.474 ± 0.049	3.428ValLys: 3.428 ± 0.045	5.762ValLeu: 5.762 ± 0.057	1.273ValMet: 1.273 ± 0.025	2.954ValAsn: 2.954 ± 0.047	2.288ValPro: 2.288 ± 0.033	2.103ValGln: 2.103 ± 0.031	2.731ValArg: 2.731 ± 0.036	4.322ValSer: 4.322 ± 0.05	3.981ValThr: 3.981 ± 0.061	4.229ValVal: 4.229 ± 0.049	0.735ValTrp: 0.735 ± 0.02	1.821ValTyr: 1.821 ± 0.03	0.0ValXaa: 0.0 ± 0.0
Trp	0.73TrpAla: 0.73 ± 0.02	0.16TrpCys: 0.16 ± 0.009	0.627TrpAsp: 0.627 ± 0.016	0.8TrpGlu: 0.8 ± 0.022	0.598TrpPhe: 0.598 ± 0.017	0.909TrpGly: 0.909 ± 0.024	0.36TrpHis: 0.36 ± 0.014	0.87TrpIle: 0.87 ± 0.02	0.665TrpLys: 0.665 ± 0.02	1.959TrpLeu: 1.959 ± 0.038	0.285TrpMet: 0.285 ± 0.011	0.691TrpAsn: 0.691 ± 0.019	0.131TrpPro: 0.131 ± 0.008	1.313TrpGln: 1.313 ± 0.027	0.703TrpArg: 0.703 ± 0.019	0.944TrpSer: 0.944 ± 0.024	0.568TrpThr: 0.568 ± 0.018	0.709TrpVal: 0.709 ± 0.019	0.226TrpTrp: 0.226 ± 0.011	0.406TrpTyr: 0.406 ± 0.015	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.853TyrAla: 1.853 ± 0.034	0.498TyrCys: 0.498 ± 0.016	1.616TyrAsp: 1.616 ± 0.039	1.769TyrGlu: 1.769 ± 0.031	1.534TyrPhe: 1.534 ± 0.03	2.053TyrGly: 2.053 ± 0.034	0.703TyrHis: 0.703 ± 0.019	1.89TyrIle: 1.89 ± 0.031	1.45TyrLys: 1.45 ± 0.028	4.044TyrLeu: 4.044 ± 0.053	0.428TyrMet: 0.428 ± 0.015	1.431TyrAsn: 1.431 ± 0.031	1.578TyrPro: 1.578 ± 0.025	2.355TyrGln: 2.355 ± 0.035	1.988TyrArg: 1.988 ± 0.034	2.282TyrSer: 2.282 ± 0.035	1.549TyrThr: 1.549 ± 0.032	1.602TyrVal: 1.602 ± 0.03	0.583TyrTrp: 0.583 ± 0.018	1.246TyrTyr: 1.246 ± 0.028	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 7698 proteins (2095954 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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