Amino acid dipepetide frequency for Magnaporthe oryzae (strain 70-15 / ATCC MYA-4617 / FGSC 8958) (Rice blast fungus) (Pyricularia oryzae)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
11.837AlaAla: 11.837 ± 0.092
1.155AlaCys: 1.155 ± 0.018
4.789AlaAsp: 4.789 ± 0.033
5.547AlaGlu: 5.547 ± 0.049
3.044AlaPhe: 3.044 ± 0.027
6.99AlaGly: 6.99 ± 0.046
1.853AlaHis: 1.853 ± 0.019
3.994AlaIle: 3.994 ± 0.031
4.321AlaLys: 4.321 ± 0.037
7.712AlaLeu: 7.712 ± 0.044
2.156AlaMet: 2.156 ± 0.022
3.048AlaAsn: 3.048 ± 0.023
5.52AlaPro: 5.52 ± 0.052
3.606AlaGln: 3.606 ± 0.034
5.621AlaArg: 5.621 ± 0.035
7.805AlaSer: 7.805 ± 0.054
5.941AlaThr: 5.941 ± 0.044
6.155AlaVal: 6.155 ± 0.037
1.206AlaTrp: 1.206 ± 0.016
2.04AlaTyr: 2.04 ± 0.019
0.0AlaXaa: 0.0 ± 0.0
Cys
1.013CysAla: 1.013 ± 0.016
0.276CysCys: 0.276 ± 0.008
0.682CysAsp: 0.682 ± 0.012
0.602CysGlu: 0.602 ± 0.012
0.519CysPhe: 0.519 ± 0.01
1.042CysGly: 1.042 ± 0.02
0.325CysHis: 0.325 ± 0.008
0.654CysIle: 0.654 ± 0.012
0.534CysLys: 0.534 ± 0.011
1.226CysLeu: 1.226 ± 0.015
0.293CysMet: 0.293 ± 0.007
0.456CysAsn: 0.456 ± 0.01
0.703CysPro: 0.703 ± 0.013
0.473CysGln: 0.473 ± 0.01
0.861CysArg: 0.861 ± 0.014
0.952CysSer: 0.952 ± 0.015
0.714CysThr: 0.714 ± 0.014
0.828CysVal: 0.828 ± 0.014
0.207CysTrp: 0.207 ± 0.006
0.339CysTyr: 0.339 ± 0.007
0.0CysXaa: 0.0 ± 0.0
Asp
5.165AspAla: 5.165 ± 0.035
0.672AspCys: 0.672 ± 0.014
4.626AspAsp: 4.626 ± 0.044
4.445AspGlu: 4.445 ± 0.032
2.11AspPhe: 2.11 ± 0.021
4.618AspGly: 4.618 ± 0.034
1.21AspHis: 1.21 ± 0.017
2.517AspIle: 2.517 ± 0.022
2.595AspLys: 2.595 ± 0.031
4.833AspLeu: 4.833 ± 0.036
1.378AspMet: 1.378 ± 0.017
1.834AspAsn: 1.834 ± 0.018
3.291AspPro: 3.291 ± 0.028
1.937AspGln: 1.937 ± 0.019
3.237AspArg: 3.237 ± 0.032
4.104AspSer: 4.104 ± 0.035
2.656AspThr: 2.656 ± 0.025
3.814AspVal: 3.814 ± 0.029
0.879AspTrp: 0.879 ± 0.015
1.485AspTyr: 1.485 ± 0.017
0.0AspXaa: 0.0 ± 0.0
Glu
5.703GluAla: 5.703 ± 0.049
0.609GluCys: 0.609 ± 0.011
4.096GluAsp: 4.096 ± 0.037
4.88GluGlu: 4.88 ± 0.052
1.802GluPhe: 1.802 ± 0.019
3.658GluGly: 3.658 ± 0.03
1.266GluHis: 1.266 ± 0.014
2.624GluIle: 2.624 ± 0.023
3.381GluLys: 3.381 ± 0.036
5.03GluLeu: 5.03 ± 0.039
1.487GluMet: 1.487 ± 0.017
2.027GluAsn: 2.027 ± 0.021
2.939GluPro: 2.939 ± 0.047
2.457GluGln: 2.457 ± 0.028
3.888GluArg: 3.888 ± 0.035
3.93GluSer: 3.93 ± 0.028
3.304GluThr: 3.304 ± 0.029
3.562GluVal: 3.562 ± 0.031
0.841GluTrp: 0.841 ± 0.013
1.462GluTyr: 1.462 ± 0.017
0.0GluXaa: 0.0 ± 0.0
Phe
3.113PheAla: 3.113 ± 0.027
0.556PheCys: 0.556 ± 0.009
2.171PheAsp: 2.171 ± 0.02
1.979PheGlu: 1.979 ± 0.02
1.493PhePhe: 1.493 ± 0.019
2.878PheGly: 2.878 ± 0.033
0.781PheHis: 0.781 ± 0.012
1.547PheIle: 1.547 ± 0.018
1.4PheLys: 1.4 ± 0.015
3.099PheLeu: 3.099 ± 0.028
0.759PheMet: 0.759 ± 0.013
1.297PheAsn: 1.297 ± 0.019
1.861PhePro: 1.861 ± 0.019
1.245PheGln: 1.245 ± 0.013
1.955PheArg: 1.955 ± 0.019
2.776PheSer: 2.776 ± 0.027
1.955PheThr: 1.955 ± 0.022
2.429PheVal: 2.429 ± 0.025
0.614PheTrp: 0.614 ± 0.011
0.991PheTyr: 0.991 ± 0.014
0.0PheXaa: 0.0 ± 0.0
Gly
6.408GlyAla: 6.408 ± 0.047
0.969GlyCys: 0.969 ± 0.017
4.034GlyAsp: 4.034 ± 0.031
3.706GlyGlu: 3.706 ± 0.031
2.794GlyPhe: 2.794 ± 0.027
7.338GlyGly: 7.338 ± 0.071
1.723GlyHis: 1.723 ± 0.021
3.331GlyIle: 3.331 ± 0.027
3.517GlyLys: 3.517 ± 0.032
6.142GlyLeu: 6.142 ± 0.04
1.754GlyMet: 1.754 ± 0.02
2.746GlyAsn: 2.746 ± 0.027
3.849GlyPro: 3.849 ± 0.035
2.825GlyGln: 2.825 ± 0.027
4.784GlyArg: 4.784 ± 0.036
6.38GlySer: 6.38 ± 0.05
4.219GlyThr: 4.219 ± 0.035
4.636GlyVal: 4.636 ± 0.034
1.188GlyTrp: 1.188 ± 0.017
2.032GlyTyr: 2.032 ± 0.021
0.0GlyXaa: 0.0 ± 0.0
His
1.826HisAla: 1.826 ± 0.017
0.335HisCys: 0.335 ± 0.007
1.278HisAsp: 1.278 ± 0.018
1.225HisGlu: 1.225 ± 0.014
0.842HisPhe: 0.842 ± 0.013
1.788HisGly: 1.788 ± 0.022
0.92HisHis: 0.92 ± 0.021
1.047HisIle: 1.047 ± 0.013
0.92HisLys: 0.92 ± 0.013
2.068HisLeu: 2.068 ± 0.02
0.524HisMet: 0.524 ± 0.009
0.802HisAsn: 0.802 ± 0.011
1.547HisPro: 1.547 ± 0.017
1.048HisGln: 1.048 ± 0.015
1.563HisArg: 1.563 ± 0.017
1.742HisSer: 1.742 ± 0.019
1.184HisThr: 1.184 ± 0.015
1.483HisVal: 1.483 ± 0.019
0.307HisTrp: 0.307 ± 0.008
0.659HisTyr: 0.659 ± 0.012
0.0HisXaa: 0.0 ± 0.0
Ile
3.847IleAla: 3.847 ± 0.031
0.68IleCys: 0.68 ± 0.011
2.539IleAsp: 2.539 ± 0.022
2.46IleGlu: 2.46 ± 0.025
1.734IlePhe: 1.734 ± 0.023
2.924IleGly: 2.924 ± 0.026
1.005IleHis: 1.005 ± 0.014
2.103IleIle: 2.103 ± 0.029
2.068IleLys: 2.068 ± 0.019
3.921IleLeu: 3.921 ± 0.034
1.026IleMet: 1.026 ± 0.013
1.647IleAsn: 1.647 ± 0.019
2.778IlePro: 2.778 ± 0.028
1.611IleGln: 1.611 ± 0.02
2.572IleArg: 2.572 ± 0.023
3.405IleSer: 3.405 ± 0.032
2.527IleThr: 2.527 ± 0.022
2.937IleVal: 2.937 ± 0.024
0.65IleTrp: 0.65 ± 0.01
1.204IleTyr: 1.204 ± 0.014
0.0IleXaa: 0.0 ± 0.0
Lys
4.408LysAla: 4.408 ± 0.038
0.511LysCys: 0.511 ± 0.011
2.737LysAsp: 2.737 ± 0.028
3.09LysGlu: 3.09 ± 0.035
1.367LysPhe: 1.367 ± 0.019
3.047LysGly: 3.047 ± 0.029
1.05LysHis: 1.05 ± 0.016
2.074LysIle: 2.074 ± 0.022
3.397LysLys: 3.397 ± 0.057
3.914LysLeu: 3.914 ± 0.035
1.068LysMet: 1.068 ± 0.015
1.645LysAsn: 1.645 ± 0.018
2.917LysPro: 2.917 ± 0.03
1.847LysGln: 1.847 ± 0.022
3.263LysArg: 3.263 ± 0.027
3.383LysSer: 3.383 ± 0.028
2.874LysThr: 2.874 ± 0.025
2.767LysVal: 2.767 ± 0.019
0.616LysTrp: 0.616 ± 0.009
1.231LysTyr: 1.231 ± 0.015
0.0LysXaa: 0.0 ± 0.0
Leu
8.289LeuAla: 8.289 ± 0.041
1.173LeuCys: 1.173 ± 0.018
5.038LeuAsp: 5.038 ± 0.034
5.188LeuGlu: 5.188 ± 0.044
3.009LeuPhe: 3.009 ± 0.03
6.118LeuGly: 6.118 ± 0.04
2.008LeuHis: 2.008 ± 0.019
3.36LeuIle: 3.36 ± 0.029
3.818LeuLys: 3.818 ± 0.034
7.874LeuLeu: 7.874 ± 0.068
1.79LeuMet: 1.79 ± 0.021
2.804LeuAsn: 2.804 ± 0.024
5.445LeuPro: 5.445 ± 0.04
3.544LeuGln: 3.544 ± 0.035
5.746LeuArg: 5.746 ± 0.039
6.681LeuSer: 6.681 ± 0.041
4.411LeuThr: 4.411 ± 0.03
5.534LeuVal: 5.534 ± 0.035
1.149LeuTrp: 1.149 ± 0.017
2.055LeuTyr: 2.055 ± 0.022
0.0LeuXaa: 0.0 ± 0.0
Met
2.483MetAla: 2.483 ± 0.023
0.256MetCys: 0.256 ± 0.007
1.317MetAsp: 1.317 ± 0.017
1.265MetGlu: 1.265 ± 0.014
0.757MetPhe: 0.757 ± 0.011
1.624MetGly: 1.624 ± 0.019
0.531MetHis: 0.531 ± 0.01
0.936MetIle: 0.936 ± 0.012
0.9MetLys: 0.9 ± 0.013
1.914MetLeu: 1.914 ± 0.022
0.628MetMet: 0.628 ± 0.011
0.759MetAsn: 0.759 ± 0.012
1.444MetPro: 1.444 ± 0.017
0.933MetGln: 0.933 ± 0.015
1.444MetArg: 1.444 ± 0.016
1.944MetSer: 1.944 ± 0.021
1.34MetThr: 1.34 ± 0.018
1.436MetVal: 1.436 ± 0.018
0.285MetTrp: 0.285 ± 0.007
0.528MetTyr: 0.528 ± 0.01
0.0MetXaa: 0.0 ± 0.0
Asn
2.985AsnAla: 2.985 ± 0.023
0.46AsnCys: 0.46 ± 0.01
1.878AsnAsp: 1.878 ± 0.018
1.765AsnGlu: 1.765 ± 0.017
1.284AsnPhe: 1.284 ± 0.015
3.091AsnGly: 3.091 ± 0.03
0.814AsnHis: 0.814 ± 0.013
1.758AsnIle: 1.758 ± 0.021
1.606AsnLys: 1.606 ± 0.016
2.98AsnLeu: 2.98 ± 0.022
0.898AsnMet: 0.898 ± 0.012
1.593AsnAsn: 1.593 ± 0.026
2.415AsnPro: 2.415 ± 0.023
1.288AsnGln: 1.288 ± 0.018
1.935AsnArg: 1.935 ± 0.018
2.707AsnSer: 2.707 ± 0.024
1.997AsnThr: 1.997 ± 0.02
2.185AsnVal: 2.185 ± 0.023
0.529AsnTrp: 0.529 ± 0.01
0.948AsnTyr: 0.948 ± 0.01
0.0AsnXaa: 0.0 ± 0.0
Pro
6.284ProAla: 6.284 ± 0.046
0.564ProCys: 0.564 ± 0.012
3.318ProAsp: 3.318 ± 0.025
3.859ProGlu: 3.859 ± 0.038
1.901ProPhe: 1.901 ± 0.02
4.619ProGly: 4.619 ± 0.037
1.309ProHis: 1.309 ± 0.017
2.388ProIle: 2.388 ± 0.026
2.778ProLys: 2.778 ± 0.026
4.657ProLeu: 4.657 ± 0.03
1.22ProMet: 1.22 ± 0.015
2.123ProAsn: 2.123 ± 0.022
5.786ProPro: 5.786 ± 0.082
2.612ProGln: 2.612 ± 0.031
3.795ProArg: 3.795 ± 0.032
5.957ProSer: 5.957 ± 0.053
4.142ProThr: 4.142 ± 0.041
3.815ProVal: 3.815 ± 0.032
0.759ProTrp: 0.759 ± 0.011
1.39ProTyr: 1.39 ± 0.019
0.0ProXaa: 0.0 ± 0.0
Gln
3.673GlnAla: 3.673 ± 0.032
0.44GlnCys: 0.44 ± 0.009
2.093GlnAsp: 2.093 ± 0.022
2.291GlnGlu: 2.291 ± 0.027
1.197GlnPhe: 1.197 ± 0.016
2.629GlnGly: 2.629 ± 0.023
1.143GlnHis: 1.143 ± 0.016
1.707GlnIle: 1.707 ± 0.019
1.887GlnLys: 1.887 ± 0.024
3.375GlnLeu: 3.375 ± 0.028
0.912GlnMet: 0.912 ± 0.015
1.457GlnAsn: 1.457 ± 0.017
2.816GlnPro: 2.816 ± 0.032
3.115GlnGln: 3.115 ± 0.058
2.71GlnArg: 2.71 ± 0.024
2.976GlnSer: 2.976 ± 0.026
2.341GlnThr: 2.341 ± 0.022
2.273GlnVal: 2.273 ± 0.023
0.557GlnTrp: 0.557 ± 0.009
1.042GlnTyr: 1.042 ± 0.015
0.0GlnXaa: 0.0 ± 0.0
Arg
5.189ArgAla: 5.189 ± 0.036
0.809ArgCys: 0.809 ± 0.015
3.682ArgAsp: 3.682 ± 0.039
3.764ArgGlu: 3.764 ± 0.038
2.155ArgPhe: 2.155 ± 0.022
4.277ArgGly: 4.277 ± 0.035
1.674ArgHis: 1.674 ± 0.017
2.783ArgIle: 2.783 ± 0.025
3.34ArgLys: 3.34 ± 0.029
5.62ArgLeu: 5.62 ± 0.034
1.443ArgMet: 1.443 ± 0.017
2.234ArgAsn: 2.234 ± 0.023
3.952ArgPro: 3.952 ± 0.04
2.877ArgGln: 2.877 ± 0.024
5.685ArgArg: 5.685 ± 0.047
5.041ArgSer: 5.041 ± 0.043
3.42ArgThr: 3.42 ± 0.024
3.504ArgVal: 3.504 ± 0.027
0.956ArgTrp: 0.956 ± 0.014
1.596ArgTyr: 1.596 ± 0.02
0.0ArgXaa: 0.0 ± 0.0
Ser
7.082SerAla: 7.082 ± 0.048
0.93SerCys: 0.93 ± 0.014
4.084SerAsp: 4.084 ± 0.03
3.865SerGlu: 3.865 ± 0.033
2.813SerPhe: 2.813 ± 0.026
6.105SerGly: 6.105 ± 0.043
1.835SerHis: 1.835 ± 0.021
3.586SerIle: 3.586 ± 0.025
3.545SerLys: 3.545 ± 0.028
6.702SerLeu: 6.702 ± 0.047
1.763SerMet: 1.763 ± 0.022
2.899SerAsn: 2.899 ± 0.026
5.734SerPro: 5.734 ± 0.059
3.229SerGln: 3.229 ± 0.03
5.367SerArg: 5.367 ± 0.043
8.957SerSer: 8.957 ± 0.074
5.45SerThr: 5.45 ± 0.043
4.545SerVal: 4.545 ± 0.031
1.095SerTrp: 1.095 ± 0.014
1.854SerTyr: 1.854 ± 0.02
0.0SerXaa: 0.0 ± 0.0
Thr
5.761ThrAla: 5.761 ± 0.045
0.793ThrCys: 0.793 ± 0.013
2.732ThrAsp: 2.732 ± 0.022
2.968ThrGlu: 2.968 ± 0.027
2.059ThrPhe: 2.059 ± 0.02
4.363ThrGly: 4.363 ± 0.038
1.201ThrHis: 1.201 ± 0.016
2.712ThrIle: 2.712 ± 0.026
2.602ThrLys: 2.602 ± 0.025
4.793ThrLeu: 4.793 ± 0.034
1.266ThrMet: 1.266 ± 0.015
2.024ThrAsn: 2.024 ± 0.02
4.458ThrPro: 4.458 ± 0.038
2.071ThrGln: 2.071 ± 0.019
3.29ThrArg: 3.29 ± 0.022
5.21ThrSer: 5.21 ± 0.049
4.481ThrThr: 4.481 ± 0.05
3.801ThrVal: 3.801 ± 0.031
0.814ThrTrp: 0.814 ± 0.013
1.455ThrTyr: 1.455 ± 0.015
0.0ThrXaa: 0.0 ± 0.0
Val
6.06ValAla: 6.06 ± 0.036
0.878ValCys: 0.878 ± 0.014
3.863ValAsp: 3.863 ± 0.029
3.874ValGlu: 3.874 ± 0.029
2.419ValPhe: 2.419 ± 0.022
4.34ValGly: 4.34 ± 0.037
1.393ValHis: 1.393 ± 0.017
2.665ValIle: 2.665 ± 0.027
2.872ValLys: 2.872 ± 0.025
5.567ValLeu: 5.567 ± 0.038
1.4ValMet: 1.4 ± 0.017
2.148ValAsn: 2.148 ± 0.019
3.816ValPro: 3.816 ± 0.033
2.347ValGln: 2.347 ± 0.021
3.698ValArg: 3.698 ± 0.032
4.604ValSer: 4.604 ± 0.035
3.609ValThr: 3.609 ± 0.034
4.757ValVal: 4.757 ± 0.037
0.886ValTrp: 0.886 ± 0.014
1.666ValTyr: 1.666 ± 0.019
0.0ValXaa: 0.0 ± 0.0
Trp
1.205TrpAla: 1.205 ± 0.017
0.212TrpCys: 0.212 ± 0.007
0.905TrpAsp: 0.905 ± 0.016
0.798TrpGlu: 0.798 ± 0.013
0.527TrpPhe: 0.527 ± 0.01
0.944TrpGly: 0.944 ± 0.015
0.365TrpHis: 0.365 ± 0.009
0.677TrpIle: 0.677 ± 0.011
0.702TrpLys: 0.702 ± 0.012
1.301TrpLeu: 1.301 ± 0.019
0.357TrpMet: 0.357 ± 0.009
0.559TrpAsn: 0.559 ± 0.011
0.656TrpPro: 0.656 ± 0.012
0.569TrpGln: 0.569 ± 0.01
1.0TrpArg: 1.0 ± 0.015
1.006TrpSer: 1.006 ± 0.014
0.889TrpThr: 0.889 ± 0.014
0.881TrpVal: 0.881 ± 0.014
0.281TrpTrp: 0.281 ± 0.008
0.399TrpTyr: 0.399 ± 0.009
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.008TyrAla: 2.008 ± 0.018
0.422TyrCys: 0.422 ± 0.01
1.545TyrAsp: 1.545 ± 0.019
1.374TyrGlu: 1.374 ± 0.015
1.073TyrPhe: 1.073 ± 0.014
1.982TyrGly: 1.982 ± 0.021
0.704TyrHis: 0.704 ± 0.012
1.171TyrIle: 1.171 ± 0.016
1.022TyrLys: 1.022 ± 0.014
2.303TyrLeu: 2.303 ± 0.022
0.604TyrMet: 0.604 ± 0.01
1.013TyrAsn: 1.013 ± 0.013
1.351TyrPro: 1.351 ± 0.019
1.001TyrGln: 1.001 ± 0.011
1.588TyrArg: 1.588 ± 0.019
1.881TyrSer: 1.881 ± 0.018
1.403TyrThr: 1.403 ± 0.015
1.518TyrVal: 1.518 ± 0.018
0.414TyrTrp: 0.414 ± 0.009
0.833TyrTyr: 0.833 ± 0.015
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 12792 proteins (5652975 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski