Amino acid dipepetide frequency for Longilinea arvoryzae

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
11.697AlaAla: 11.697 ± 0.132
1.122AlaCys: 1.122 ± 0.03
5.224AlaAsp: 5.224 ± 0.067
5.85AlaGlu: 5.85 ± 0.081
3.808AlaPhe: 3.808 ± 0.061
8.795AlaGly: 8.795 ± 0.088
1.798AlaHis: 1.798 ± 0.036
5.719AlaIle: 5.719 ± 0.063
2.533AlaLys: 2.533 ± 0.051
11.415AlaLeu: 11.415 ± 0.128
2.424AlaMet: 2.424 ± 0.045
3.107AlaAsn: 3.107 ± 0.052
4.075AlaPro: 4.075 ± 0.067
3.76AlaGln: 3.76 ± 0.06
6.014AlaArg: 6.014 ± 0.085
5.19AlaSer: 5.19 ± 0.07
4.621AlaThr: 4.621 ± 0.085
7.396AlaVal: 7.396 ± 0.103
1.585AlaTrp: 1.585 ± 0.036
2.839AlaTyr: 2.839 ± 0.048
0.0AlaXaa: 0.0 ± 0.0
Cys
0.83CysAla: 0.83 ± 0.03
0.105CysCys: 0.105 ± 0.011
0.512CysAsp: 0.512 ± 0.022
0.419CysGlu: 0.419 ± 0.019
0.308CysPhe: 0.308 ± 0.015
0.975CysGly: 0.975 ± 0.03
0.229CysHis: 0.229 ± 0.02
0.443CysIle: 0.443 ± 0.02
0.277CysLys: 0.277 ± 0.015
0.896CysLeu: 0.896 ± 0.026
0.187CysMet: 0.187 ± 0.014
0.325CysAsn: 0.325 ± 0.015
0.59CysPro: 0.59 ± 0.027
0.352CysGln: 0.352 ± 0.016
0.568CysArg: 0.568 ± 0.023
0.568CysSer: 0.568 ± 0.025
0.483CysThr: 0.483 ± 0.022
0.564CysVal: 0.564 ± 0.021
0.141CysTrp: 0.141 ± 0.012
0.257CysTyr: 0.257 ± 0.013
0.0CysXaa: 0.0 ± 0.0
Asp
4.861AspAla: 4.861 ± 0.071
0.483AspCys: 0.483 ± 0.021
2.378AspAsp: 2.378 ± 0.046
3.419AspGlu: 3.419 ± 0.069
2.349AspPhe: 2.349 ± 0.045
4.345AspGly: 4.345 ± 0.081
1.058AspHis: 1.058 ± 0.026
2.737AspIle: 2.737 ± 0.052
1.392AspLys: 1.392 ± 0.038
6.354AspLeu: 6.354 ± 0.085
1.059AspMet: 1.059 ± 0.028
1.391AspAsn: 1.391 ± 0.039
3.41AspPro: 3.41 ± 0.059
2.226AspGln: 2.226 ± 0.044
3.259AspArg: 3.259 ± 0.052
2.623AspSer: 2.623 ± 0.051
2.376AspThr: 2.376 ± 0.045
3.494AspVal: 3.494 ± 0.059
1.011AspTrp: 1.011 ± 0.033
1.782AspTyr: 1.782 ± 0.042
0.0AspXaa: 0.0 ± 0.0
Glu
5.477GluAla: 5.477 ± 0.083
0.408GluCys: 0.408 ± 0.018
2.768GluAsp: 2.768 ± 0.05
3.658GluGlu: 3.658 ± 0.068
2.028GluPhe: 2.028 ± 0.036
3.583GluGly: 3.583 ± 0.051
1.14GluHis: 1.14 ± 0.031
4.132GluIle: 4.132 ± 0.063
3.133GluLys: 3.133 ± 0.065
5.704GluLeu: 5.704 ± 0.08
1.818GluMet: 1.818 ± 0.04
2.452GluAsn: 2.452 ± 0.047
2.561GluPro: 2.561 ± 0.051
2.444GluGln: 2.444 ± 0.053
3.907GluArg: 3.907 ± 0.062
3.01GluSer: 3.01 ± 0.053
3.488GluThr: 3.488 ± 0.054
3.905GluVal: 3.905 ± 0.058
0.869GluTrp: 0.869 ± 0.025
1.554GluTyr: 1.554 ± 0.04
0.0GluXaa: 0.0 ± 0.0
Phe
3.372PheAla: 3.372 ± 0.051
0.441PheCys: 0.441 ± 0.02
2.3PheAsp: 2.3 ± 0.046
2.188PheGlu: 2.188 ± 0.043
1.91PhePhe: 1.91 ± 0.044
3.282PheGly: 3.282 ± 0.053
0.781PheHis: 0.781 ± 0.023
2.385PheIle: 2.385 ± 0.05
1.243PheLys: 1.243 ± 0.032
4.258PheLeu: 4.258 ± 0.07
0.845PheMet: 0.845 ± 0.027
1.391PheAsn: 1.391 ± 0.035
1.811PhePro: 1.811 ± 0.04
1.411PheGln: 1.411 ± 0.034
1.987PheArg: 1.987 ± 0.041
2.984PheSer: 2.984 ± 0.056
2.536PheThr: 2.536 ± 0.053
2.504PheVal: 2.504 ± 0.049
0.716PheTrp: 0.716 ± 0.028
1.337PheTyr: 1.337 ± 0.036
0.0PheXaa: 0.0 ± 0.0
Gly
6.604GlyAla: 6.604 ± 0.087
0.854GlyCys: 0.854 ± 0.032
3.739GlyAsp: 3.739 ± 0.063
4.505GlyGlu: 4.505 ± 0.058
3.232GlyPhe: 3.232 ± 0.055
6.062GlyGly: 6.062 ± 0.096
1.4GlyHis: 1.4 ± 0.033
4.835GlyIle: 4.835 ± 0.063
3.449GlyLys: 3.449 ± 0.059
9.246GlyLeu: 9.246 ± 0.108
2.358GlyMet: 2.358 ± 0.044
2.573GlyAsn: 2.573 ± 0.052
2.618GlyPro: 2.618 ± 0.048
3.252GlyGln: 3.252 ± 0.05
4.334GlyArg: 4.334 ± 0.059
4.589GlySer: 4.589 ± 0.071
3.937GlyThr: 3.937 ± 0.066
5.936GlyVal: 5.936 ± 0.075
1.585GlyTrp: 1.585 ± 0.039
2.74GlyTyr: 2.74 ± 0.044
0.0GlyXaa: 0.0 ± 0.0
His
1.707HisAla: 1.707 ± 0.04
0.243HisCys: 0.243 ± 0.013
0.828HisAsp: 0.828 ± 0.027
0.998HisGlu: 0.998 ± 0.026
0.909HisPhe: 0.909 ± 0.028
1.412HisGly: 1.412 ± 0.036
0.488HisHis: 0.488 ± 0.019
1.125HisIle: 1.125 ± 0.034
0.538HisLys: 0.538 ± 0.018
2.28HisLeu: 2.28 ± 0.046
0.434HisMet: 0.434 ± 0.02
0.656HisAsn: 0.656 ± 0.025
1.472HisPro: 1.472 ± 0.033
0.721HisGln: 0.721 ± 0.021
1.094HisArg: 1.094 ± 0.03
1.076HisSer: 1.076 ± 0.028
1.013HisThr: 1.013 ± 0.03
1.139HisVal: 1.139 ± 0.031
0.333HisTrp: 0.333 ± 0.016
0.642HisTyr: 0.642 ± 0.024
0.0HisXaa: 0.0 ± 0.0
Ile
5.6IleAla: 5.6 ± 0.078
0.569IleCys: 0.569 ± 0.024
3.467IleAsp: 3.467 ± 0.047
3.475IleGlu: 3.475 ± 0.056
2.463IlePhe: 2.463 ± 0.05
4.765IleGly: 4.765 ± 0.068
1.277IleHis: 1.277 ± 0.034
3.099IleIle: 3.099 ± 0.059
1.698IleLys: 1.698 ± 0.038
6.982IleLeu: 6.982 ± 0.092
0.946IleMet: 0.946 ± 0.027
1.937IleAsn: 1.937 ± 0.045
3.522IlePro: 3.522 ± 0.061
2.573IleGln: 2.573 ± 0.044
3.388IleArg: 3.388 ± 0.056
3.906IleSer: 3.906 ± 0.055
3.331IleThr: 3.331 ± 0.054
4.004IleVal: 4.004 ± 0.062
0.774IleTrp: 0.774 ± 0.026
1.889IleTyr: 1.889 ± 0.042
0.0IleXaa: 0.0 ± 0.0
Lys
3.241LysAla: 3.241 ± 0.056
0.232LysCys: 0.232 ± 0.015
1.761LysAsp: 1.761 ± 0.04
2.148LysGlu: 2.148 ± 0.043
1.115LysPhe: 1.115 ± 0.033
2.38LysGly: 2.38 ± 0.042
0.55LysHis: 0.55 ± 0.021
2.337LysIle: 2.337 ± 0.05
1.708LysLys: 1.708 ± 0.046
3.231LysLeu: 3.231 ± 0.057
1.02LysMet: 1.02 ± 0.026
1.402LysAsn: 1.402 ± 0.038
1.976LysPro: 1.976 ± 0.038
1.242LysGln: 1.242 ± 0.029
2.11LysArg: 2.11 ± 0.041
2.035LysSer: 2.035 ± 0.044
2.189LysThr: 2.189 ± 0.038
2.525LysVal: 2.525 ± 0.049
0.468LysTrp: 0.468 ± 0.02
0.984LysTyr: 0.984 ± 0.031
0.0LysXaa: 0.0 ± 0.0
Leu
12.411LeuAla: 12.411 ± 0.133
0.918LeuCys: 0.918 ± 0.03
5.874LeuAsp: 5.874 ± 0.069
6.298LeuGlu: 6.298 ± 0.087
4.217LeuPhe: 4.217 ± 0.066
8.179LeuGly: 8.179 ± 0.095
1.995LeuHis: 1.995 ± 0.041
6.506LeuIle: 6.506 ± 0.091
4.067LeuLys: 4.067 ± 0.065
11.818LeuLeu: 11.818 ± 0.141
2.392LeuMet: 2.392 ± 0.039
3.729LeuAsn: 3.729 ± 0.054
6.545LeuPro: 6.545 ± 0.08
4.013LeuGln: 4.013 ± 0.061
6.671LeuArg: 6.671 ± 0.085
6.889LeuSer: 6.889 ± 0.078
6.216LeuThr: 6.216 ± 0.074
8.151LeuVal: 8.151 ± 0.092
1.444LeuTrp: 1.444 ± 0.041
2.721LeuTyr: 2.721 ± 0.05
0.0LeuXaa: 0.0 ± 0.0
Met
2.532MetAla: 2.532 ± 0.045
0.158MetCys: 0.158 ± 0.011
1.366MetAsp: 1.366 ± 0.029
1.261MetGlu: 1.261 ± 0.031
0.625MetPhe: 0.625 ± 0.022
1.798MetGly: 1.798 ± 0.042
0.432MetHis: 0.432 ± 0.019
1.385MetIle: 1.385 ± 0.036
1.098MetLys: 1.098 ± 0.026
2.522MetLeu: 2.522 ± 0.047
0.568MetMet: 0.568 ± 0.023
0.975MetAsn: 0.975 ± 0.029
1.333MetPro: 1.333 ± 0.034
0.946MetGln: 0.946 ± 0.025
1.425MetArg: 1.425 ± 0.034
1.3MetSer: 1.3 ± 0.03
1.457MetThr: 1.457 ± 0.036
1.798MetVal: 1.798 ± 0.043
0.187MetTrp: 0.187 ± 0.013
0.449MetTyr: 0.449 ± 0.02
0.0MetXaa: 0.0 ± 0.0
Asn
3.087AsnAla: 3.087 ± 0.052
0.314AsnCys: 0.314 ± 0.017
1.619AsnAsp: 1.619 ± 0.035
1.707AsnGlu: 1.707 ± 0.04
1.34AsnPhe: 1.34 ± 0.037
2.85AsnGly: 2.85 ± 0.063
0.718AsnHis: 0.718 ± 0.025
1.859AsnIle: 1.859 ± 0.041
0.931AsnLys: 0.931 ± 0.033
4.063AsnLeu: 4.063 ± 0.059
0.678AsnMet: 0.678 ± 0.022
1.206AsnAsn: 1.206 ± 0.039
2.427AsnPro: 2.427 ± 0.045
1.494AsnGln: 1.494 ± 0.036
2.122AsnArg: 2.122 ± 0.042
1.964AsnSer: 1.964 ± 0.048
1.871AsnThr: 1.871 ± 0.051
2.112AsnVal: 2.112 ± 0.044
0.629AsnTrp: 0.629 ± 0.022
1.103AsnTyr: 1.103 ± 0.034
0.0AsnXaa: 0.0 ± 0.0
Pro
5.945ProAla: 5.945 ± 0.077
0.333ProCys: 0.333 ± 0.018
3.563ProAsp: 3.563 ± 0.056
4.074ProGlu: 4.074 ± 0.059
2.104ProPhe: 2.104 ± 0.047
4.261ProGly: 4.261 ± 0.062
0.861ProHis: 0.861 ± 0.03
2.741ProIle: 2.741 ± 0.049
1.4ProLys: 1.4 ± 0.032
5.11ProLeu: 5.11 ± 0.077
1.093ProMet: 1.093 ± 0.03
1.713ProAsn: 1.713 ± 0.04
2.264ProPro: 2.264 ± 0.048
2.062ProGln: 2.062 ± 0.039
2.553ProArg: 2.553 ± 0.047
2.737ProSer: 2.737 ± 0.041
3.314ProThr: 3.314 ± 0.09
4.164ProVal: 4.164 ± 0.058
0.755ProTrp: 0.755 ± 0.024
1.505ProTyr: 1.505 ± 0.037
0.0ProXaa: 0.0 ± 0.0
Gln
4.741GlnAla: 4.741 ± 0.069
0.236GlnCys: 0.236 ± 0.013
1.779GlnAsp: 1.779 ± 0.043
2.111GlnGlu: 2.111 ± 0.045
1.344GlnPhe: 1.344 ± 0.032
2.679GlnGly: 2.679 ± 0.043
0.705GlnHis: 0.705 ± 0.027
2.578GlnIle: 2.578 ± 0.048
1.675GlnLys: 1.675 ± 0.038
3.487GlnLeu: 3.487 ± 0.057
1.013GlnMet: 1.013 ± 0.025
1.512GlnAsn: 1.512 ± 0.031
2.519GlnPro: 2.519 ± 0.042
1.667GlnGln: 1.667 ± 0.041
2.811GlnArg: 2.811 ± 0.054
2.365GlnSer: 2.365 ± 0.045
2.481GlnThr: 2.481 ± 0.049
3.159GlnVal: 3.159 ± 0.053
0.525GlnTrp: 0.525 ± 0.023
0.981GlnTyr: 0.981 ± 0.03
0.0GlnXaa: 0.0 ± 0.0
Arg
5.328ArgAla: 5.328 ± 0.084
0.524ArgCys: 0.524 ± 0.022
2.852ArgAsp: 2.852 ± 0.052
3.632ArgGlu: 3.632 ± 0.07
2.508ArgPhe: 2.508 ± 0.043
3.708ArgGly: 3.708 ± 0.056
1.094ArgHis: 1.094 ± 0.03
3.691ArgIle: 3.691 ± 0.059
2.512ArgLys: 2.512 ± 0.049
7.162ArgLeu: 7.162 ± 0.09
1.677ArgMet: 1.677 ± 0.036
1.888ArgAsn: 1.888 ± 0.039
2.815ArgPro: 2.815 ± 0.057
2.861ArgGln: 2.861 ± 0.056
4.171ArgArg: 4.171 ± 0.073
3.402ArgSer: 3.402 ± 0.053
2.845ArgThr: 2.845 ± 0.045
4.171ArgVal: 4.171 ± 0.056
1.041ArgTrp: 1.041 ± 0.028
1.867ArgTyr: 1.867 ± 0.038
0.0ArgXaa: 0.0 ± 0.0
Ser
5.723SerAla: 5.723 ± 0.067
0.433SerCys: 0.433 ± 0.02
2.99SerAsp: 2.99 ± 0.05
3.105SerGlu: 3.105 ± 0.054
2.3SerPhe: 2.3 ± 0.042
5.476SerGly: 5.476 ± 0.076
1.106SerHis: 1.106 ± 0.029
3.707SerIle: 3.707 ± 0.061
1.789SerLys: 1.789 ± 0.042
6.462SerLeu: 6.462 ± 0.083
1.45SerMet: 1.45 ± 0.036
1.932SerAsn: 1.932 ± 0.041
3.115SerPro: 3.115 ± 0.054
2.333SerGln: 2.333 ± 0.047
3.17SerArg: 3.17 ± 0.046
3.549SerSer: 3.549 ± 0.066
3.269SerThr: 3.269 ± 0.06
3.95SerVal: 3.95 ± 0.057
0.872SerTrp: 0.872 ± 0.028
1.547SerTyr: 1.547 ± 0.043
0.0SerXaa: 0.0 ± 0.0
Thr
5.545ThrAla: 5.545 ± 0.089
0.489ThrCys: 0.489 ± 0.023
2.651ThrAsp: 2.651 ± 0.05
2.614ThrGlu: 2.614 ± 0.052
2.225ThrPhe: 2.225 ± 0.046
4.844ThrGly: 4.844 ± 0.062
1.156ThrHis: 1.156 ± 0.029
3.206ThrIle: 3.206 ± 0.052
1.285ThrLys: 1.285 ± 0.034
6.579ThrLeu: 6.579 ± 0.074
0.924ThrMet: 0.924 ± 0.027
1.77ThrAsn: 1.77 ± 0.052
4.005ThrPro: 4.005 ± 0.089
2.068ThrGln: 2.068 ± 0.039
3.114ThrArg: 3.114 ± 0.043
3.128ThrSer: 3.128 ± 0.056
2.944ThrThr: 2.944 ± 0.066
3.892ThrVal: 3.892 ± 0.069
0.878ThrTrp: 0.878 ± 0.027
1.725ThrTyr: 1.725 ± 0.051
0.0ThrXaa: 0.0 ± 0.0
Val
6.448ValAla: 6.448 ± 0.088
0.74ValCys: 0.74 ± 0.028
3.913ValAsp: 3.913 ± 0.054
4.336ValGlu: 4.336 ± 0.06
2.887ValPhe: 2.887 ± 0.054
5.006ValGly: 5.006 ± 0.071
1.333ValHis: 1.333 ± 0.037
4.712ValIle: 4.712 ± 0.062
2.461ValLys: 2.461 ± 0.048
7.886ValLeu: 7.886 ± 0.084
1.695ValMet: 1.695 ± 0.04
2.476ValAsn: 2.476 ± 0.042
3.272ValPro: 3.272 ± 0.053
2.702ValGln: 2.702 ± 0.05
4.054ValArg: 4.054 ± 0.064
4.363ValSer: 4.363 ± 0.057
4.157ValThr: 4.157 ± 0.057
5.363ValVal: 5.363 ± 0.082
1.09ValTrp: 1.09 ± 0.032
2.114ValTyr: 2.114 ± 0.042
0.0ValXaa: 0.0 ± 0.0
Trp
1.216TrpAla: 1.216 ± 0.029
0.097TrpCys: 0.097 ± 0.009
0.767TrpAsp: 0.767 ± 0.026
0.796TrpGlu: 0.796 ± 0.027
0.606TrpPhe: 0.606 ± 0.019
1.127TrpGly: 1.127 ± 0.031
0.272TrpHis: 0.272 ± 0.015
0.969TrpIle: 0.969 ± 0.028
0.704TrpLys: 0.704 ± 0.026
2.083TrpLeu: 2.083 ± 0.049
0.525TrpMet: 0.525 ± 0.02
0.625TrpAsn: 0.625 ± 0.022
0.625TrpPro: 0.625 ± 0.022
0.857TrpGln: 0.857 ± 0.028
0.934TrpArg: 0.934 ± 0.03
0.812TrpSer: 0.812 ± 0.027
0.783TrpThr: 0.783 ± 0.027
1.172TrpVal: 1.172 ± 0.035
0.285TrpTrp: 0.285 ± 0.017
0.43TrpTyr: 0.43 ± 0.019
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.609TyrAla: 2.609 ± 0.052
0.33TyrCys: 0.33 ± 0.016
1.655TyrAsp: 1.655 ± 0.049
1.444TyrGlu: 1.444 ± 0.036
1.407TyrPhe: 1.407 ± 0.031
2.317TyrGly: 2.317 ± 0.046
0.718TyrHis: 0.718 ± 0.024
1.494TyrIle: 1.494 ± 0.036
0.762TyrLys: 0.762 ± 0.028
3.517TyrLeu: 3.517 ± 0.055
0.509TyrMet: 0.509 ± 0.019
1.036TyrAsn: 1.036 ± 0.032
1.595TyrPro: 1.595 ± 0.035
1.382TyrGln: 1.382 ± 0.03
2.062TyrArg: 2.062 ± 0.041
1.788TyrSer: 1.788 ± 0.041
1.73TyrThr: 1.73 ± 0.044
1.61TyrVal: 1.61 ± 0.035
0.498TyrTrp: 0.498 ± 0.018
1.077TyrTyr: 1.077 ± 0.035
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3871 proteins (1319558 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski