Amino acid dipepetide frequency for Flammulina velutipes browning virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.718AlaAla: 6.718 ± 4.076
0.0AlaCys: 0.0 ± 0.0
3.839AlaAsp: 3.839 ± 1.093
2.879AlaGlu: 2.879 ± 0.942
4.798AlaPhe: 4.798 ± 0.309
1.919AlaGly: 1.919 ± 0.158
1.919AlaHis: 1.919 ± 0.158
3.839AlaIle: 3.839 ± 1.093
0.96AlaLys: 0.96 ± 0.625
8.637AlaLeu: 8.637 ± 1.402
2.879AlaMet: 2.879 ± 0.942
2.879AlaAsn: 2.879 ± 0.467
7.678AlaPro: 7.678 ± 3.451
0.96AlaGln: 0.96 ± 0.784
2.879AlaArg: 2.879 ± 0.942
5.758AlaSer: 5.758 ± 0.934
3.839AlaThr: 3.839 ± 3.134
5.758AlaVal: 5.758 ± 3.293
0.96AlaTrp: 0.96 ± 0.784
0.96AlaTyr: 0.96 ± 0.784
0.0AlaXaa: 0.0 ± 0.0
Cys
1.919CysAla: 1.919 ± 1.251
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
0.96CysGly: 0.96 ± 0.625
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.96CysLys: 0.96 ± 0.625
0.0CysLeu: 0.0 ± 0.0
0.96CysMet: 0.96 ± 0.784
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
0.96CysSer: 0.96 ± 0.784
1.919CysThr: 1.919 ± 1.567
1.919CysVal: 1.919 ± 0.158
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.839AspAla: 3.839 ± 3.134
0.0AspCys: 0.0 ± 0.0
0.96AspAsp: 0.96 ± 0.625
1.919AspGlu: 1.919 ± 1.251
0.0AspPhe: 0.0 ± 0.0
1.919AspGly: 1.919 ± 1.251
0.96AspHis: 0.96 ± 0.625
2.879AspIle: 2.879 ± 0.467
2.879AspLys: 2.879 ± 1.876
4.798AspLeu: 4.798 ± 1.718
1.919AspMet: 1.919 ± 1.567
2.879AspAsn: 2.879 ± 0.467
4.798AspPro: 4.798 ± 1.1
0.0AspGln: 0.0 ± 0.0
0.96AspArg: 0.96 ± 0.625
8.637AspSer: 8.637 ± 2.811
3.839AspThr: 3.839 ± 0.316
1.919AspVal: 1.919 ± 0.158
1.919AspTrp: 1.919 ± 1.251
3.839AspTyr: 3.839 ± 1.093
0.0AspXaa: 0.0 ± 0.0
Glu
2.879GluAla: 2.879 ± 0.467
0.96GluCys: 0.96 ± 0.784
0.0GluAsp: 0.0 ± 0.0
0.0GluGlu: 0.0 ± 0.0
2.879GluPhe: 2.879 ± 0.467
0.0GluGly: 0.0 ± 0.0
4.798GluHis: 4.798 ± 1.1
0.0GluIle: 0.0 ± 0.0
0.96GluLys: 0.96 ± 0.625
1.919GluLeu: 1.919 ± 0.158
0.96GluMet: 0.96 ± 0.784
0.0GluAsn: 0.0 ± 0.0
1.919GluPro: 1.919 ± 0.158
1.919GluGln: 1.919 ± 1.251
0.96GluArg: 0.96 ± 0.625
2.879GluSer: 2.879 ± 0.942
4.798GluThr: 4.798 ± 1.718
0.96GluVal: 0.96 ± 0.625
0.0GluTrp: 0.0 ± 0.0
2.879GluTyr: 2.879 ± 1.876
0.0GluXaa: 0.0 ± 0.0
Phe
5.758PheAla: 5.758 ± 3.293
0.0PheCys: 0.0 ± 0.0
2.879PheAsp: 2.879 ± 1.876
3.839PheGlu: 3.839 ± 1.093
3.839PhePhe: 3.839 ± 1.093
2.879PheGly: 2.879 ± 0.467
1.919PheHis: 1.919 ± 1.251
0.0PheIle: 0.0 ± 0.0
1.919PheLys: 1.919 ± 1.251
8.637PheLeu: 8.637 ± 0.007
0.96PheMet: 0.96 ± 0.625
5.758PheAsn: 5.758 ± 0.475
3.839PhePro: 3.839 ± 0.316
0.96PheGln: 0.96 ± 0.625
2.879PheArg: 2.879 ± 0.467
6.718PheSer: 6.718 ± 1.56
1.919PheThr: 1.919 ± 1.251
3.839PheVal: 3.839 ± 0.316
1.919PheTrp: 1.919 ± 0.158
0.96PheTyr: 0.96 ± 0.625
0.0PheXaa: 0.0 ± 0.0
Gly
0.96GlyAla: 0.96 ± 0.784
0.0GlyCys: 0.0 ± 0.0
1.919GlyAsp: 1.919 ± 1.251
0.0GlyGlu: 0.0 ± 0.0
4.798GlyPhe: 4.798 ± 3.127
1.919GlyGly: 1.919 ± 0.158
0.0GlyHis: 0.0 ± 0.0
3.839GlyIle: 3.839 ± 2.502
1.919GlyLys: 1.919 ± 0.158
4.798GlyLeu: 4.798 ± 0.309
0.0GlyMet: 0.0 ± 0.0
0.0GlyAsn: 0.0 ± 0.0
3.839GlyPro: 3.839 ± 1.725
1.919GlyGln: 1.919 ± 0.158
0.96GlyArg: 0.96 ± 0.625
2.879GlySer: 2.879 ± 0.942
5.758GlyThr: 5.758 ± 1.884
2.879GlyVal: 2.879 ± 1.876
1.919GlyTrp: 1.919 ± 0.158
1.919GlyTyr: 1.919 ± 1.251
0.0GlyXaa: 0.0 ± 0.0
His
1.919HisAla: 1.919 ± 1.567
0.0HisCys: 0.0 ± 0.0
1.919HisAsp: 1.919 ± 0.158
2.879HisGlu: 2.879 ± 1.876
1.919HisPhe: 1.919 ± 0.158
2.879HisGly: 2.879 ± 0.942
1.919HisHis: 1.919 ± 0.158
0.0HisIle: 0.0 ± 0.0
0.0HisLys: 0.0 ± 0.0
3.839HisLeu: 3.839 ± 2.502
0.96HisMet: 0.96 ± 0.784
2.879HisAsn: 2.879 ± 1.876
1.919HisPro: 1.919 ± 0.158
2.879HisGln: 2.879 ± 2.351
0.96HisArg: 0.96 ± 0.625
0.0HisSer: 0.0 ± 0.0
3.839HisThr: 3.839 ± 0.316
1.919HisVal: 1.919 ± 0.158
0.96HisTrp: 0.96 ± 0.784
2.879HisTyr: 2.879 ± 0.467
0.0HisXaa: 0.0 ± 0.0
Ile
0.96IleAla: 0.96 ± 0.625
0.96IleCys: 0.96 ± 0.625
2.879IleAsp: 2.879 ± 1.876
1.919IleGlu: 1.919 ± 1.251
1.919IlePhe: 1.919 ± 1.251
2.879IleGly: 2.879 ± 0.467
1.919IleHis: 1.919 ± 1.251
2.879IleIle: 2.879 ± 0.942
2.879IleLys: 2.879 ± 0.467
4.798IleLeu: 4.798 ± 1.718
0.96IleMet: 0.96 ± 0.784
4.798IleAsn: 4.798 ± 0.309
7.678IlePro: 7.678 ± 0.633
0.96IleGln: 0.96 ± 0.625
0.96IleArg: 0.96 ± 0.625
3.839IleSer: 3.839 ± 1.725
0.96IleThr: 0.96 ± 0.784
0.96IleVal: 0.96 ± 0.625
0.96IleTrp: 0.96 ± 0.625
2.879IleTyr: 2.879 ± 0.942
0.0IleXaa: 0.0 ± 0.0
Lys
2.879LysAla: 2.879 ± 0.467
0.0LysCys: 0.0 ± 0.0
1.919LysAsp: 1.919 ± 1.251
1.919LysGlu: 1.919 ± 0.158
1.919LysPhe: 1.919 ± 1.251
2.879LysGly: 2.879 ± 1.876
0.96LysHis: 0.96 ± 0.784
1.919LysIle: 1.919 ± 0.158
1.919LysLys: 1.919 ± 1.251
4.798LysLeu: 4.798 ± 1.718
1.919LysMet: 1.919 ± 0.576
1.919LysAsn: 1.919 ± 0.158
4.798LysPro: 4.798 ± 1.1
0.0LysGln: 0.0 ± 0.0
0.96LysArg: 0.96 ± 0.625
7.678LysSer: 7.678 ± 3.594
0.0LysThr: 0.0 ± 0.0
1.919LysVal: 1.919 ± 1.251
0.0LysTrp: 0.0 ± 0.0
1.919LysTyr: 1.919 ± 0.158
0.0LysXaa: 0.0 ± 0.0
Leu
8.637LeuAla: 8.637 ± 0.007
0.96LeuCys: 0.96 ± 0.625
6.718LeuAsp: 6.718 ± 2.969
0.96LeuGlu: 0.96 ± 0.784
6.718LeuPhe: 6.718 ± 0.151
5.758LeuGly: 5.758 ± 0.934
1.919LeuHis: 1.919 ± 1.251
3.839LeuIle: 3.839 ± 2.502
2.879LeuLys: 2.879 ± 1.876
9.597LeuLeu: 9.597 ± 0.618
0.96LeuMet: 0.96 ± 0.625
7.678LeuAsn: 7.678 ± 0.633
6.718LeuPro: 6.718 ± 1.258
3.839LeuGln: 3.839 ± 1.725
5.758LeuArg: 5.758 ± 0.475
7.678LeuSer: 7.678 ± 0.776
5.758LeuThr: 5.758 ± 0.934
3.839LeuVal: 3.839 ± 3.134
1.919LeuTrp: 1.919 ± 1.251
5.758LeuTyr: 5.758 ± 0.934
0.0LeuXaa: 0.0 ± 0.0
Met
0.0MetAla: 0.0 ± 0.0
0.96MetCys: 0.96 ± 0.784
3.839MetAsp: 3.839 ± 1.725
0.96MetGlu: 0.96 ± 0.784
1.919MetPhe: 1.919 ± 0.158
0.96MetGly: 0.96 ± 0.625
0.96MetHis: 0.96 ± 0.625
0.96MetIle: 0.96 ± 0.625
0.96MetLys: 0.96 ± 0.784
1.919MetLeu: 1.919 ± 1.251
0.96MetMet: 0.96 ± 0.784
0.0MetAsn: 0.0 ± 0.0
0.96MetPro: 0.96 ± 0.784
0.0MetGln: 0.0 ± 0.0
0.0MetArg: 0.0 ± 0.0
2.879MetSer: 2.879 ± 0.942
0.0MetThr: 0.0 ± 0.0
0.96MetVal: 0.96 ± 0.625
0.0MetTrp: 0.0 ± 0.0
0.96MetTyr: 0.96 ± 0.784
0.0MetXaa: 0.0 ± 0.0
Asn
1.919AsnAla: 1.919 ± 1.251
0.0AsnCys: 0.0 ± 0.0
3.839AsnAsp: 3.839 ± 0.316
2.879AsnGlu: 2.879 ± 0.467
5.758AsnPhe: 5.758 ± 0.475
4.798AsnGly: 4.798 ± 0.309
2.879AsnHis: 2.879 ± 0.467
3.839AsnIle: 3.839 ± 1.725
0.96AsnLys: 0.96 ± 0.625
7.678AsnLeu: 7.678 ± 0.633
0.0AsnMet: 0.0 ± 0.0
3.839AsnAsn: 3.839 ± 1.093
2.879AsnPro: 2.879 ± 0.467
0.0AsnGln: 0.0 ± 0.0
3.839AsnArg: 3.839 ± 1.093
3.839AsnSer: 3.839 ± 1.725
0.96AsnThr: 0.96 ± 0.625
5.758AsnVal: 5.758 ± 1.884
1.919AsnTrp: 1.919 ± 0.158
1.919AsnTyr: 1.919 ± 0.158
0.0AsnXaa: 0.0 ± 0.0
Pro
4.798ProAla: 4.798 ± 1.1
2.879ProCys: 2.879 ± 0.942
3.839ProAsp: 3.839 ± 0.316
1.919ProGlu: 1.919 ± 0.158
3.839ProPhe: 3.839 ± 0.316
1.919ProGly: 1.919 ± 1.567
3.839ProHis: 3.839 ± 1.725
6.718ProIle: 6.718 ± 0.151
3.839ProLys: 3.839 ± 0.316
7.678ProLeu: 7.678 ± 0.633
0.0ProMet: 0.0 ± 0.0
5.758ProAsn: 5.758 ± 2.343
3.839ProPro: 3.839 ± 1.725
2.879ProGln: 2.879 ± 0.467
2.879ProArg: 2.879 ± 0.942
4.798ProSer: 4.798 ± 1.1
7.678ProThr: 7.678 ± 2.042
6.718ProVal: 6.718 ± 2.667
1.919ProTrp: 1.919 ± 0.158
0.96ProTyr: 0.96 ± 0.784
0.0ProXaa: 0.0 ± 0.0
Gln
1.919GlnAla: 1.919 ± 0.158
1.919GlnCys: 1.919 ± 0.158
0.96GlnAsp: 0.96 ± 0.625
0.96GlnGlu: 0.96 ± 0.784
1.919GlnPhe: 1.919 ± 1.251
2.879GlnGly: 2.879 ± 1.876
0.0GlnHis: 0.0 ± 0.0
1.919GlnIle: 1.919 ± 1.567
4.798GlnLys: 4.798 ± 1.1
0.0GlnLeu: 0.0 ± 0.0
0.0GlnMet: 0.0 ± 0.0
1.919GlnAsn: 1.919 ± 0.158
0.96GlnPro: 0.96 ± 0.784
0.96GlnGln: 0.96 ± 0.625
2.879GlnArg: 2.879 ± 0.467
1.919GlnSer: 1.919 ± 0.158
0.96GlnThr: 0.96 ± 0.784
1.919GlnVal: 1.919 ± 0.158
0.0GlnTrp: 0.0 ± 0.0
0.96GlnTyr: 0.96 ± 0.784
0.0GlnXaa: 0.0 ± 0.0
Arg
4.798ArgAla: 4.798 ± 0.309
0.0ArgCys: 0.0 ± 0.0
1.919ArgAsp: 1.919 ± 0.158
0.96ArgGlu: 0.96 ± 0.784
1.919ArgPhe: 1.919 ± 0.158
0.96ArgGly: 0.96 ± 0.625
0.96ArgHis: 0.96 ± 0.784
0.96ArgIle: 0.96 ± 0.784
0.96ArgLys: 0.96 ± 0.625
7.678ArgLeu: 7.678 ± 0.776
1.919ArgMet: 1.919 ± 0.158
1.919ArgAsn: 1.919 ± 0.158
3.839ArgPro: 3.839 ± 1.093
1.919ArgGln: 1.919 ± 1.251
0.96ArgArg: 0.96 ± 0.625
4.798ArgSer: 4.798 ± 0.309
3.839ArgThr: 3.839 ± 2.502
0.96ArgVal: 0.96 ± 0.784
0.0ArgTrp: 0.0 ± 0.0
3.839ArgTyr: 3.839 ± 0.316
0.0ArgXaa: 0.0 ± 0.0
Ser
12.476SerAla: 12.476 ± 4.551
0.96SerCys: 0.96 ± 0.625
4.798SerAsp: 4.798 ± 1.718
1.919SerGlu: 1.919 ± 0.158
5.758SerPhe: 5.758 ± 0.934
3.839SerGly: 3.839 ± 0.316
3.839SerHis: 3.839 ± 1.093
2.879SerIle: 2.879 ± 1.876
3.839SerLys: 3.839 ± 0.316
4.798SerLeu: 4.798 ± 0.309
0.96SerMet: 0.96 ± 0.406
4.798SerAsn: 4.798 ± 1.1
4.798SerPro: 4.798 ± 2.509
3.839SerGln: 3.839 ± 1.725
5.758SerArg: 5.758 ± 0.934
4.798SerSer: 4.798 ± 1.1
5.758SerThr: 5.758 ± 1.884
6.718SerVal: 6.718 ± 2.969
0.96SerTrp: 0.96 ± 0.784
1.919SerTyr: 1.919 ± 1.251
0.0SerXaa: 0.0 ± 0.0
Thr
2.879ThrAla: 2.879 ± 0.942
0.0ThrCys: 0.0 ± 0.0
4.798ThrAsp: 4.798 ± 2.509
1.919ThrGlu: 1.919 ± 0.158
1.919ThrPhe: 1.919 ± 1.567
0.0ThrGly: 0.0 ± 0.0
1.919ThrHis: 1.919 ± 0.158
7.678ThrIle: 7.678 ± 0.776
3.839ThrLys: 3.839 ± 1.093
6.718ThrLeu: 6.718 ± 1.258
0.96ThrMet: 0.96 ± 0.625
1.919ThrAsn: 1.919 ± 0.158
3.839ThrPro: 3.839 ± 1.725
3.839ThrGln: 3.839 ± 0.316
3.839ThrArg: 3.839 ± 1.725
4.798ThrSer: 4.798 ± 1.1
6.718ThrThr: 6.718 ± 2.667
5.758ThrVal: 5.758 ± 0.934
0.96ThrTrp: 0.96 ± 0.625
1.919ThrTyr: 1.919 ± 1.567
0.96ThrXaa: 0.96 ± 0.784
Val
1.919ValAla: 1.919 ± 0.158
0.0ValCys: 0.0 ± 0.0
2.879ValAsp: 2.879 ± 0.942
1.919ValGlu: 1.919 ± 1.251
4.798ValPhe: 4.798 ± 0.309
0.96ValGly: 0.96 ± 0.784
2.879ValHis: 2.879 ± 0.467
2.879ValIle: 2.879 ± 1.876
3.839ValLys: 3.839 ± 1.093
4.798ValLeu: 4.798 ± 1.1
0.96ValMet: 0.96 ± 0.625
4.798ValAsn: 4.798 ± 3.918
4.798ValPro: 4.798 ± 1.1
0.0ValGln: 0.0 ± 0.0
3.839ValArg: 3.839 ± 2.502
5.758ValSer: 5.758 ± 0.475
5.758ValThr: 5.758 ± 1.884
0.96ValVal: 0.96 ± 0.625
0.0ValTrp: 0.0 ± 0.0
3.839ValTyr: 3.839 ± 1.725
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.96TrpAsp: 0.96 ± 0.625
0.96TrpGlu: 0.96 ± 0.625
0.0TrpPhe: 0.0 ± 0.0
0.96TrpGly: 0.96 ± 0.625
1.919TrpHis: 1.919 ± 1.567
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
0.96TrpLeu: 0.96 ± 0.784
0.96TrpMet: 0.96 ± 0.625
0.96TrpAsn: 0.96 ± 0.784
3.839TrpPro: 3.839 ± 1.093
0.96TrpGln: 0.96 ± 0.625
0.96TrpArg: 0.96 ± 0.784
1.919TrpSer: 1.919 ± 0.158
0.96TrpThr: 0.96 ± 0.784
0.96TrpVal: 0.96 ± 0.625
0.0TrpTrp: 0.0 ± 0.0
0.96TrpTyr: 0.96 ± 0.625
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.879TyrAla: 2.879 ± 1.876
0.0TyrCys: 0.0 ± 0.0
0.0TyrAsp: 0.0 ± 0.0
0.96TyrGlu: 0.96 ± 0.625
4.798TyrPhe: 4.798 ± 0.309
0.96TyrGly: 0.96 ± 0.784
0.96TyrHis: 0.96 ± 0.784
1.919TyrIle: 1.919 ± 0.158
1.919TyrLys: 1.919 ± 1.251
3.839TyrLeu: 3.839 ± 0.316
0.0TyrMet: 0.0 ± 0.0
4.798TyrAsn: 4.798 ± 0.309
5.758TyrPro: 5.758 ± 2.343
1.919TyrGln: 1.919 ± 0.158
2.879TyrArg: 2.879 ± 0.942
3.839TyrSer: 3.839 ± 1.725
1.919TyrThr: 1.919 ± 1.567
0.96TyrVal: 0.96 ± 0.784
0.96TyrTrp: 0.96 ± 0.625
4.798TyrTyr: 4.798 ± 0.309
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.96XaaTrp: 0.96 ± 0.784
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1043 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski