Amino acid dipepetide frequency for Acetomicrobium mobile (strain ATCC BAA-54 / DSM 13181 / JCM 12221 / NGA) (Acetomicrobium mobile)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.864AlaAla: 6.864 ± 0.127
1.3AlaCys: 1.3 ± 0.041
3.711AlaAsp: 3.711 ± 0.083
4.658AlaGlu: 4.658 ± 0.104
3.664AlaPhe: 3.664 ± 0.068
6.106AlaGly: 6.106 ± 0.109
1.436AlaHis: 1.436 ± 0.041
6.309AlaIle: 6.309 ± 0.117
4.995AlaLys: 4.995 ± 0.097
10.177AlaLeu: 10.177 ± 0.155
2.627AlaMet: 2.627 ± 0.07
2.48AlaAsn: 2.48 ± 0.062
2.491AlaPro: 2.491 ± 0.065
2.384AlaGln: 2.384 ± 0.063
4.418AlaArg: 4.418 ± 0.082
5.29AlaSer: 5.29 ± 0.106
3.571AlaThr: 3.571 ± 0.077
6.583AlaVal: 6.583 ± 0.093
0.86AlaTrp: 0.86 ± 0.031
2.442AlaTyr: 2.442 ± 0.057
0.0AlaXaa: 0.0 ± 0.0
Cys
0.966CysAla: 0.966 ± 0.04
0.225CysCys: 0.225 ± 0.02
0.826CysAsp: 0.826 ± 0.033
0.714CysGlu: 0.714 ± 0.03
0.531CysPhe: 0.531 ± 0.026
1.46CysGly: 1.46 ± 0.062
0.325CysHis: 0.325 ± 0.021
0.922CysIle: 0.922 ± 0.038
0.689CysLys: 0.689 ± 0.037
1.243CysLeu: 1.243 ± 0.046
0.337CysMet: 0.337 ± 0.022
0.472CysAsn: 0.472 ± 0.027
0.819CysPro: 0.819 ± 0.038
0.297CysGln: 0.297 ± 0.022
0.765CysArg: 0.765 ± 0.029
0.792CysSer: 0.792 ± 0.033
0.548CysThr: 0.548 ± 0.03
0.879CysVal: 0.879 ± 0.039
0.14CysTrp: 0.14 ± 0.015
0.409CysTyr: 0.409 ± 0.026
0.0CysXaa: 0.0 ± 0.0
Asp
3.908AspAla: 3.908 ± 0.078
0.566AspCys: 0.566 ± 0.034
2.925AspAsp: 2.925 ± 0.077
4.773AspGlu: 4.773 ± 0.077
2.231AspPhe: 2.231 ± 0.063
3.764AspGly: 3.764 ± 0.083
0.956AspHis: 0.956 ± 0.035
4.361AspIle: 4.361 ± 0.083
3.061AspLys: 3.061 ± 0.07
5.863AspLeu: 5.863 ± 0.089
1.776AspMet: 1.776 ± 0.053
1.376AspAsn: 1.376 ± 0.056
2.737AspPro: 2.737 ± 0.069
1.129AspGln: 1.129 ± 0.043
2.657AspArg: 2.657 ± 0.067
2.34AspSer: 2.34 ± 0.063
2.0AspThr: 2.0 ± 0.051
5.022AspVal: 5.022 ± 0.101
0.56AspTrp: 0.56 ± 0.03
1.59AspTyr: 1.59 ± 0.052
0.0AspXaa: 0.0 ± 0.0
Glu
6.33GluAla: 6.33 ± 0.105
0.685GluCys: 0.685 ± 0.036
3.787GluAsp: 3.787 ± 0.082
6.435GluGlu: 6.435 ± 0.127
2.087GluPhe: 2.087 ± 0.055
5.372GluGly: 5.372 ± 0.089
1.143GluHis: 1.143 ± 0.046
5.201GluIle: 5.201 ± 0.097
4.427GluLys: 4.427 ± 0.084
6.606GluLeu: 6.606 ± 0.111
2.108GluMet: 2.108 ± 0.06
2.202GluAsn: 2.202 ± 0.064
2.133GluPro: 2.133 ± 0.068
1.702GluGln: 1.702 ± 0.05
4.593GluArg: 4.593 ± 0.095
3.244GluSer: 3.244 ± 0.072
2.667GluThr: 2.667 ± 0.062
5.595GluVal: 5.595 ± 0.095
0.806GluTrp: 0.806 ± 0.037
1.67GluTyr: 1.67 ± 0.055
0.0GluXaa: 0.0 ± 0.0
Phe
3.242PheAla: 3.242 ± 0.07
0.722PheCys: 0.722 ± 0.031
2.436PheAsp: 2.436 ± 0.064
2.559PheGlu: 2.559 ± 0.056
1.808PhePhe: 1.808 ± 0.059
3.416PheGly: 3.416 ± 0.079
0.688PheHis: 0.688 ± 0.035
2.699PheIle: 2.699 ± 0.071
2.179PheLys: 2.179 ± 0.062
4.428PheLeu: 4.428 ± 0.094
1.222PheMet: 1.222 ± 0.042
1.313PheAsn: 1.313 ± 0.044
1.87PhePro: 1.87 ± 0.054
0.908PheGln: 0.908 ± 0.039
1.739PheArg: 1.739 ± 0.053
2.6PheSer: 2.6 ± 0.063
1.791PheThr: 1.791 ± 0.056
3.205PheVal: 3.205 ± 0.079
0.511PheTrp: 0.511 ± 0.031
1.354PheTyr: 1.354 ± 0.047
0.0PheXaa: 0.0 ± 0.0
Gly
5.976GlyAla: 5.976 ± 0.13
1.217GlyCys: 1.217 ± 0.05
3.878GlyAsp: 3.878 ± 0.084
4.853GlyGlu: 4.853 ± 0.091
3.536GlyPhe: 3.536 ± 0.076
6.173GlyGly: 6.173 ± 0.118
1.526GlyHis: 1.526 ± 0.052
6.413GlyIle: 6.413 ± 0.1
5.49GlyLys: 5.49 ± 0.096
8.16GlyLeu: 8.16 ± 0.121
2.45GlyMet: 2.45 ± 0.064
2.64GlyAsn: 2.64 ± 0.072
2.582GlyPro: 2.582 ± 0.066
2.102GlyGln: 2.102 ± 0.058
4.242GlyArg: 4.242 ± 0.079
4.464GlySer: 4.464 ± 0.095
3.696GlyThr: 3.696 ± 0.082
6.101GlyVal: 6.101 ± 0.093
0.992GlyTrp: 0.992 ± 0.043
2.834GlyTyr: 2.834 ± 0.065
0.0GlyXaa: 0.0 ± 0.0
His
1.189HisAla: 1.189 ± 0.041
0.262HisCys: 0.262 ± 0.021
0.906HisAsp: 0.906 ± 0.039
1.096HisGlu: 1.096 ± 0.037
0.802HisPhe: 0.802 ± 0.037
1.339HisGly: 1.339 ± 0.047
0.375HisHis: 0.375 ± 0.026
1.373HisIle: 1.373 ± 0.042
0.774HisLys: 0.774 ± 0.041
1.868HisLeu: 1.868 ± 0.056
0.477HisMet: 0.477 ± 0.028
0.582HisAsn: 0.582 ± 0.032
1.18HisPro: 1.18 ± 0.042
0.383HisGln: 0.383 ± 0.025
0.932HisArg: 0.932 ± 0.036
0.885HisSer: 0.885 ± 0.033
0.688HisThr: 0.688 ± 0.032
1.437HisVal: 1.437 ± 0.047
0.214HisTrp: 0.214 ± 0.019
0.579HisTyr: 0.579 ± 0.027
0.0HisXaa: 0.0 ± 0.0
Ile
6.581IleAla: 6.581 ± 0.101
0.999IleCys: 0.999 ± 0.037
4.11IleAsp: 4.11 ± 0.081
4.976IleGlu: 4.976 ± 0.094
2.934IlePhe: 2.934 ± 0.08
5.479IleGly: 5.479 ± 0.111
1.076IleHis: 1.076 ± 0.039
4.412IleIle: 4.412 ± 0.103
4.441IleLys: 4.441 ± 0.093
6.783IleLeu: 6.783 ± 0.123
1.748IleMet: 1.748 ± 0.055
2.413IleAsn: 2.413 ± 0.057
3.627IlePro: 3.627 ± 0.078
1.445IleGln: 1.445 ± 0.049
3.339IleArg: 3.339 ± 0.061
4.893IleSer: 4.893 ± 0.086
3.434IleThr: 3.434 ± 0.077
5.552IleVal: 5.552 ± 0.097
0.676IleTrp: 0.676 ± 0.033
2.247IleTyr: 2.247 ± 0.064
0.0IleXaa: 0.0 ± 0.0
Lys
5.623LysAla: 5.623 ± 0.097
0.58LysCys: 0.58 ± 0.032
3.739LysAsp: 3.739 ± 0.077
5.118LysGlu: 5.118 ± 0.095
1.802LysPhe: 1.802 ± 0.053
5.298LysGly: 5.298 ± 0.086
0.899LysHis: 0.899 ± 0.034
4.021LysIle: 4.021 ± 0.074
4.162LysLys: 4.162 ± 0.079
5.735LysLeu: 5.735 ± 0.114
1.63LysMet: 1.63 ± 0.053
2.17LysAsn: 2.17 ± 0.056
2.279LysPro: 2.279 ± 0.063
1.363LysGln: 1.363 ± 0.049
3.727LysArg: 3.727 ± 0.081
3.213LysSer: 3.213 ± 0.073
2.488LysThr: 2.488 ± 0.056
4.876LysVal: 4.876 ± 0.088
0.686LysTrp: 0.686 ± 0.029
1.779LysTyr: 1.779 ± 0.063
0.0LysXaa: 0.0 ± 0.0
Leu
9.082LeuAla: 9.082 ± 0.125
1.416LeuCys: 1.416 ± 0.049
5.45LeuAsp: 5.45 ± 0.107
6.781LeuGlu: 6.781 ± 0.108
4.078LeuPhe: 4.078 ± 0.089
8.415LeuGly: 8.415 ± 0.13
1.734LeuHis: 1.734 ± 0.048
6.541LeuIle: 6.541 ± 0.108
7.023LeuLys: 7.023 ± 0.111
10.84LeuLeu: 10.84 ± 0.174
2.647LeuMet: 2.647 ± 0.062
3.57LeuAsn: 3.57 ± 0.076
4.966LeuPro: 4.966 ± 0.093
2.911LeuGln: 2.911 ± 0.073
5.584LeuArg: 5.584 ± 0.088
7.581LeuSer: 7.581 ± 0.109
4.485LeuThr: 4.485 ± 0.083
7.28LeuVal: 7.28 ± 0.115
1.309LeuTrp: 1.309 ± 0.048
3.056LeuTyr: 3.056 ± 0.069
0.0LeuXaa: 0.0 ± 0.0
Met
2.931MetAla: 2.931 ± 0.06
0.274MetCys: 0.274 ± 0.024
1.477MetAsp: 1.477 ± 0.043
1.894MetGlu: 1.894 ± 0.056
0.843MetPhe: 0.843 ± 0.041
2.456MetGly: 2.456 ± 0.07
0.419MetHis: 0.419 ± 0.027
1.811MetIle: 1.811 ± 0.056
1.751MetLys: 1.751 ± 0.05
2.822MetLeu: 2.822 ± 0.076
0.748MetMet: 0.748 ± 0.035
0.954MetAsn: 0.954 ± 0.037
1.4MetPro: 1.4 ± 0.05
0.652MetGln: 0.652 ± 0.031
1.577MetArg: 1.577 ± 0.051
1.93MetSer: 1.93 ± 0.055
1.488MetThr: 1.488 ± 0.048
1.934MetVal: 1.934 ± 0.062
0.249MetTrp: 0.249 ± 0.019
0.597MetTyr: 0.597 ± 0.032
0.0MetXaa: 0.0 ± 0.0
Asn
2.671AsnAla: 2.671 ± 0.067
0.437AsnCys: 0.437 ± 0.026
1.723AsnAsp: 1.723 ± 0.057
1.99AsnGlu: 1.99 ± 0.059
1.385AsnPhe: 1.385 ± 0.04
2.231AsnGly: 2.231 ± 0.066
0.451AsnHis: 0.451 ± 0.026
2.677AsnIle: 2.677 ± 0.077
1.834AsnLys: 1.834 ± 0.05
3.656AsnLeu: 3.656 ± 0.084
0.966AsnMet: 0.966 ± 0.035
1.008AsnAsn: 1.008 ± 0.044
2.028AsnPro: 2.028 ± 0.057
0.746AsnGln: 0.746 ± 0.034
1.456AsnArg: 1.456 ± 0.042
1.611AsnSer: 1.611 ± 0.049
1.337AsnThr: 1.337 ± 0.044
3.021AsnVal: 3.021 ± 0.071
0.377AsnTrp: 0.377 ± 0.025
1.043AsnTyr: 1.043 ± 0.046
0.0AsnXaa: 0.0 ± 0.0
Pro
2.788ProAla: 2.788 ± 0.069
0.509ProCys: 0.509 ± 0.028
2.482ProAsp: 2.482 ± 0.071
3.333ProGlu: 3.333 ± 0.083
2.108ProPhe: 2.108 ± 0.059
3.401ProGly: 3.401 ± 0.07
0.942ProHis: 0.942 ± 0.039
2.759ProIle: 2.759 ± 0.071
2.739ProLys: 2.739 ± 0.07
4.664ProLeu: 4.664 ± 0.073
1.059ProMet: 1.059 ± 0.043
1.471ProAsn: 1.471 ± 0.04
1.702ProPro: 1.702 ± 0.047
1.353ProGln: 1.353 ± 0.041
1.885ProArg: 1.885 ± 0.051
2.79ProSer: 2.79 ± 0.073
2.025ProThr: 2.025 ± 0.051
3.43ProVal: 3.43 ± 0.078
0.634ProTrp: 0.634 ± 0.033
1.516ProTyr: 1.516 ± 0.046
0.0ProXaa: 0.0 ± 0.0
Gln
2.33GlnAla: 2.33 ± 0.063
0.294GlnCys: 0.294 ± 0.022
1.289GlnAsp: 1.289 ± 0.04
1.999GlnGlu: 1.999 ± 0.053
0.882GlnPhe: 0.882 ± 0.037
2.071GlnGly: 2.071 ± 0.06
0.357GlnHis: 0.357 ± 0.019
1.959GlnIle: 1.959 ± 0.056
1.693GlnLys: 1.693 ± 0.05
2.307GlnLeu: 2.307 ± 0.065
0.806GlnMet: 0.806 ± 0.034
0.903GlnAsn: 0.903 ± 0.039
0.842GlnPro: 0.842 ± 0.036
0.72GlnGln: 0.72 ± 0.041
1.725GlnArg: 1.725 ± 0.056
1.313GlnSer: 1.313 ± 0.05
1.057GlnThr: 1.057 ± 0.042
1.893GlnVal: 1.893 ± 0.051
0.365GlnTrp: 0.365 ± 0.025
0.726GlnTyr: 0.726 ± 0.033
0.0GlnXaa: 0.0 ± 0.0
Arg
4.108ArgAla: 4.108 ± 0.088
0.759ArgCys: 0.759 ± 0.038
2.899ArgAsp: 2.899 ± 0.074
4.03ArgGlu: 4.03 ± 0.089
2.254ArgPhe: 2.254 ± 0.057
4.053ArgGly: 4.053 ± 0.09
1.136ArgHis: 1.136 ± 0.046
3.779ArgIle: 3.779 ± 0.086
3.113ArgLys: 3.113 ± 0.07
5.558ArgLeu: 5.558 ± 0.097
1.506ArgMet: 1.506 ± 0.043
1.819ArgAsn: 1.819 ± 0.062
2.094ArgPro: 2.094 ± 0.067
1.783ArgGln: 1.783 ± 0.047
3.341ArgArg: 3.341 ± 0.078
2.85ArgSer: 2.85 ± 0.07
2.154ArgThr: 2.154 ± 0.056
3.57ArgVal: 3.57 ± 0.074
0.774ArgTrp: 0.774 ± 0.045
1.936ArgTyr: 1.936 ± 0.058
0.0ArgXaa: 0.0 ± 0.0
Ser
4.202SerAla: 4.202 ± 0.092
0.932SerCys: 0.932 ± 0.039
2.899SerAsp: 2.899 ± 0.068
3.282SerGlu: 3.282 ± 0.076
3.065SerPhe: 3.065 ± 0.073
4.973SerGly: 4.973 ± 0.101
1.071SerHis: 1.071 ± 0.045
4.179SerIle: 4.179 ± 0.092
3.536SerLys: 3.536 ± 0.079
7.094SerLeu: 7.094 ± 0.11
1.748SerMet: 1.748 ± 0.05
1.85SerAsn: 1.85 ± 0.054
2.714SerPro: 2.714 ± 0.065
1.691SerGln: 1.691 ± 0.059
3.13SerArg: 3.13 ± 0.071
4.022SerSer: 4.022 ± 0.093
2.456SerThr: 2.456 ± 0.063
4.188SerVal: 4.188 ± 0.079
0.846SerTrp: 0.846 ± 0.035
1.936SerTyr: 1.936 ± 0.047
0.0SerXaa: 0.0 ± 0.0
Thr
3.622ThrAla: 3.622 ± 0.085
0.557ThrCys: 0.557 ± 0.031
2.114ThrAsp: 2.114 ± 0.052
2.337ThrGlu: 2.337 ± 0.067
1.891ThrPhe: 1.891 ± 0.06
3.873ThrGly: 3.873 ± 0.089
0.791ThrHis: 0.791 ± 0.035
3.108ThrIle: 3.108 ± 0.081
2.34ThrLys: 2.34 ± 0.057
4.802ThrLeu: 4.802 ± 0.083
1.093ThrMet: 1.093 ± 0.044
1.468ThrAsn: 1.468 ± 0.049
2.46ThrPro: 2.46 ± 0.066
1.057ThrGln: 1.057 ± 0.038
1.979ThrArg: 1.979 ± 0.054
2.733ThrSer: 2.733 ± 0.07
2.205ThrThr: 2.205 ± 0.063
3.476ThrVal: 3.476 ± 0.076
0.517ThrTrp: 0.517 ± 0.033
1.425ThrTyr: 1.425 ± 0.053
0.0ThrXaa: 0.0 ± 0.0
Val
6.675ValAla: 6.675 ± 0.111
1.065ValCys: 1.065 ± 0.041
4.31ValAsp: 4.31 ± 0.084
5.012ValGlu: 5.012 ± 0.101
3.036ValPhe: 3.036 ± 0.074
5.659ValGly: 5.659 ± 0.106
1.259ValHis: 1.259 ± 0.045
5.769ValIle: 5.769 ± 0.104
4.635ValLys: 4.635 ± 0.084
7.768ValLeu: 7.768 ± 0.115
2.196ValMet: 2.196 ± 0.067
2.497ValAsn: 2.497 ± 0.063
3.661ValPro: 3.661 ± 0.086
1.728ValGln: 1.728 ± 0.048
3.982ValArg: 3.982 ± 0.08
4.898ValSer: 4.898 ± 0.09
4.084ValThr: 4.084 ± 0.075
6.569ValVal: 6.569 ± 0.101
0.706ValTrp: 0.706 ± 0.036
2.236ValTyr: 2.236 ± 0.061
0.0ValXaa: 0.0 ± 0.0
Trp
0.969TrpAla: 0.969 ± 0.038
0.151TrpCys: 0.151 ± 0.016
0.677TrpAsp: 0.677 ± 0.033
0.831TrpGlu: 0.831 ± 0.038
0.386TrpPhe: 0.386 ± 0.021
1.043TrpGly: 1.043 ± 0.038
0.229TrpHis: 0.229 ± 0.019
0.829TrpIle: 0.829 ± 0.038
0.692TrpLys: 0.692 ± 0.036
1.259TrpLeu: 1.259 ± 0.048
0.317TrpMet: 0.317 ± 0.023
0.463TrpAsn: 0.463 ± 0.027
0.512TrpPro: 0.512 ± 0.027
0.469TrpGln: 0.469 ± 0.028
0.68TrpArg: 0.68 ± 0.036
0.625TrpSer: 0.625 ± 0.033
0.408TrpThr: 0.408 ± 0.025
0.743TrpVal: 0.743 ± 0.037
0.22TrpTrp: 0.22 ± 0.02
0.326TrpTyr: 0.326 ± 0.021
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.305TyrAla: 2.305 ± 0.058
0.411TyrCys: 0.411 ± 0.024
1.957TyrAsp: 1.957 ± 0.06
2.12TyrGlu: 2.12 ± 0.06
1.366TyrPhe: 1.366 ± 0.04
2.745TyrGly: 2.745 ± 0.066
0.529TyrHis: 0.529 ± 0.032
2.042TyrIle: 2.042 ± 0.062
1.613TyrLys: 1.613 ± 0.051
3.117TyrLeu: 3.117 ± 0.067
0.748TyrMet: 0.748 ± 0.033
0.999TyrAsn: 0.999 ± 0.04
1.491TyrPro: 1.491 ± 0.056
0.705TyrGln: 0.705 ± 0.031
1.765TyrArg: 1.765 ± 0.051
1.742TyrSer: 1.742 ± 0.056
1.266TyrThr: 1.266 ± 0.051
2.39TyrVal: 2.39 ± 0.064
0.388TyrTrp: 0.388 ± 0.024
1.005TyrTyr: 1.005 ± 0.039
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2004 proteins (649885 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski