Amino acid dipepetide frequency for Serpula lacrymans var. lacrymans (strain S7.3) (Dry rot fungus)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.0AlaAla: 7.0 ± 0.048	1.057AlaCys: 1.057 ± 0.015	3.775AlaAsp: 3.775 ± 0.028	4.506AlaGlu: 4.506 ± 0.041	3.253AlaPhe: 3.253 ± 0.026	4.897AlaGly: 4.897 ± 0.036	1.955AlaHis: 1.955 ± 0.022	4.278AlaIle: 4.278 ± 0.034	3.757AlaLys: 3.757 ± 0.037	7.942AlaLeu: 7.942 ± 0.05	1.936AlaMet: 1.936 ± 0.023	2.85AlaAsn: 2.85 ± 0.028	4.168AlaPro: 4.168 ± 0.038	3.202AlaGln: 3.202 ± 0.03	4.566AlaArg: 4.566 ± 0.035	6.774AlaSer: 6.774 ± 0.044	4.579AlaThr: 4.579 ± 0.036	5.08AlaVal: 5.08 ± 0.031	1.103AlaTrp: 1.103 ± 0.017	2.132AlaTyr: 2.132 ± 0.025	0.0AlaXaa: 0.0 ± 0.0
Cys	0.979CysAla: 0.979 ± 0.015	0.274CysCys: 0.274 ± 0.008	0.682CysAsp: 0.682 ± 0.012	0.585CysGlu: 0.585 ± 0.012	0.563CysPhe: 0.563 ± 0.012	0.946CysGly: 0.946 ± 0.015	0.404CysHis: 0.404 ± 0.009	0.829CysIle: 0.829 ± 0.013	0.62CysLys: 0.62 ± 0.013	1.349CysLeu: 1.349 ± 0.02	0.331CysMet: 0.331 ± 0.008	0.52CysAsn: 0.52 ± 0.011	0.823CysPro: 0.823 ± 0.015	0.539CysGln: 0.539 ± 0.012	0.789CysArg: 0.789 ± 0.015	1.121CysSer: 1.121 ± 0.02	0.818CysThr: 0.818 ± 0.016	0.866CysVal: 0.866 ± 0.016	0.223CysTrp: 0.223 ± 0.007	0.461CysTyr: 0.461 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	4.281AspAla: 4.281 ± 0.03	0.64AspCys: 0.64 ± 0.01	4.081AspAsp: 4.081 ± 0.043	4.044AspGlu: 4.044 ± 0.036	2.152AspPhe: 2.152 ± 0.025	3.716AspGly: 3.716 ± 0.035	1.318AspHis: 1.318 ± 0.016	3.382AspIle: 3.382 ± 0.026	2.491AspLys: 2.491 ± 0.025	4.839AspLeu: 4.839 ± 0.04	1.292AspMet: 1.292 ± 0.019	2.011AspAsn: 2.011 ± 0.02	3.105AspPro: 3.105 ± 0.031	1.765AspGln: 1.765 ± 0.02	2.701AspArg: 2.701 ± 0.026	4.106AspSer: 4.106 ± 0.036	2.971AspThr: 2.971 ± 0.025	3.871AspVal: 3.871 ± 0.03	0.908AspTrp: 0.908 ± 0.014	1.55AspTyr: 1.55 ± 0.018	0.0AspXaa: 0.0 ± 0.0
Glu	4.503GluAla: 4.503 ± 0.043	0.73GluCys: 0.73 ± 0.013	3.93GluAsp: 3.93 ± 0.035	5.077GluGlu: 5.077 ± 0.055	1.851GluPhe: 1.851 ± 0.022	3.735GluGly: 3.735 ± 0.033	1.457GluHis: 1.457 ± 0.018	3.008GluIle: 3.008 ± 0.029	3.497GluLys: 3.497 ± 0.036	5.171GluLeu: 5.171 ± 0.042	1.382GluMet: 1.382 ± 0.018	2.141GluAsn: 2.141 ± 0.023	2.378GluPro: 2.378 ± 0.025	2.251GluGln: 2.251 ± 0.024	3.797GluArg: 3.797 ± 0.035	3.96GluSer: 3.96 ± 0.033	3.026GluThr: 3.026 ± 0.03	3.705GluVal: 3.705 ± 0.031	0.947GluTrp: 0.947 ± 0.013	1.609GluTyr: 1.609 ± 0.019	0.0GluXaa: 0.0 ± 0.0
Phe	2.995PheAla: 2.995 ± 0.025	0.6PheCys: 0.6 ± 0.011	2.246PheAsp: 2.246 ± 0.023	2.126PheGlu: 2.126 ± 0.023	1.673PhePhe: 1.673 ± 0.02	2.688PheGly: 2.688 ± 0.028	1.021PheHis: 1.021 ± 0.015	2.01PheIle: 2.01 ± 0.025	1.727PheLys: 1.727 ± 0.021	3.683PheLeu: 3.683 ± 0.032	0.854PheMet: 0.854 ± 0.015	1.512PheAsn: 1.512 ± 0.018	2.0PhePro: 2.0 ± 0.021	1.335PheGln: 1.335 ± 0.016	1.922PheArg: 1.922 ± 0.022	3.393PheSer: 3.393 ± 0.032	2.282PheThr: 2.282 ± 0.028	2.569PheVal: 2.569 ± 0.024	0.597PheTrp: 0.597 ± 0.011	1.13PheTyr: 1.13 ± 0.018	0.0PheXaa: 0.0 ± 0.0
Gly	4.662GlyAla: 4.662 ± 0.038	0.922GlyCys: 0.922 ± 0.014	3.329GlyAsp: 3.329 ± 0.023	3.402GlyGlu: 3.402 ± 0.024	2.481GlyPhe: 2.481 ± 0.028	5.071GlyGly: 5.071 ± 0.05	1.737GlyHis: 1.737 ± 0.02	3.376GlyIle: 3.376 ± 0.028	3.519GlyLys: 3.519 ± 0.032	5.649GlyLeu: 5.649 ± 0.037	1.504GlyMet: 1.504 ± 0.022	2.429GlyAsn: 2.429 ± 0.023	3.02GlyPro: 3.02 ± 0.025	2.395GlyGln: 2.395 ± 0.023	3.786GlyArg: 3.786 ± 0.033	5.324GlySer: 5.324 ± 0.038	3.797GlyThr: 3.797 ± 0.034	4.168GlyVal: 4.168 ± 0.034	1.084GlyTrp: 1.084 ± 0.017	1.872GlyTyr: 1.872 ± 0.02	0.0GlyXaa: 0.0 ± 0.0
His	1.998HisAla: 1.998 ± 0.023	0.44HisCys: 0.44 ± 0.009	1.34HisAsp: 1.34 ± 0.017	1.23HisGlu: 1.23 ± 0.017	1.096HisPhe: 1.096 ± 0.017	1.613HisGly: 1.613 ± 0.019	0.966HisHis: 0.966 ± 0.017	1.552HisIle: 1.552 ± 0.015	1.059HisLys: 1.059 ± 0.016	2.612HisLeu: 2.612 ± 0.027	0.567HisMet: 0.567 ± 0.012	1.01HisAsn: 1.01 ± 0.017	1.911HisPro: 1.911 ± 0.023	1.051HisGln: 1.051 ± 0.015	1.575HisArg: 1.575 ± 0.018	2.309HisSer: 2.309 ± 0.026	1.539HisThr: 1.539 ± 0.019	1.696HisVal: 1.696 ± 0.019	0.384HisTrp: 0.384 ± 0.01	0.793HisTyr: 0.793 ± 0.014	0.0HisXaa: 0.0 ± 0.0
Ile	4.178IleAla: 4.178 ± 0.031	0.882IleCys: 0.882 ± 0.016	2.941IleAsp: 2.941 ± 0.028	2.753IleGlu: 2.753 ± 0.024	2.157IlePhe: 2.157 ± 0.025	3.163IleGly: 3.163 ± 0.03	1.397IleHis: 1.397 ± 0.017	2.883IleIle: 2.883 ± 0.031	2.425IleLys: 2.425 ± 0.025	5.013IleLeu: 5.013 ± 0.035	1.112IleMet: 1.112 ± 0.017	2.006IleAsn: 2.006 ± 0.02	3.339IlePro: 3.339 ± 0.027	2.132IleGln: 2.132 ± 0.02	3.003IleArg: 3.003 ± 0.024	4.411IleSer: 4.411 ± 0.033	3.028IleThr: 3.028 ± 0.03	3.465IleVal: 3.465 ± 0.032	0.872IleTrp: 0.872 ± 0.013	1.53IleTyr: 1.53 ± 0.019	0.0IleXaa: 0.0 ± 0.0
Lys	4.17LysAla: 4.17 ± 0.033	0.621LysCys: 0.621 ± 0.013	2.787LysAsp: 2.787 ± 0.028	3.457LysGlu: 3.457 ± 0.036	1.509LysPhe: 1.509 ± 0.019	3.092LysGly: 3.092 ± 0.03	1.225LysHis: 1.225 ± 0.019	2.443LysIle: 2.443 ± 0.025	3.489LysLys: 3.489 ± 0.044	4.231LysLeu: 4.231 ± 0.034	1.103LysMet: 1.103 ± 0.014	1.816LysAsn: 1.816 ± 0.025	2.571LysPro: 2.571 ± 0.026	1.865LysGln: 1.865 ± 0.023	3.299LysArg: 3.299 ± 0.027	3.484LysSer: 3.484 ± 0.031	2.689LysThr: 2.689 ± 0.024	3.055LysVal: 3.055 ± 0.028	0.746LysTrp: 0.746 ± 0.013	1.477LysTyr: 1.477 ± 0.015	0.0LysXaa: 0.0 ± 0.0
Leu	7.694LeuAla: 7.694 ± 0.045	1.348LeuCys: 1.348 ± 0.018	5.197LeuAsp: 5.197 ± 0.037	5.469LeuGlu: 5.469 ± 0.041	3.544LeuPhe: 3.544 ± 0.032	5.575LeuGly: 5.575 ± 0.038	2.672LeuHis: 2.672 ± 0.028	4.24LeuIle: 4.24 ± 0.03	4.386LeuLys: 4.386 ± 0.034	9.046LeuLeu: 9.046 ± 0.058	1.888LeuMet: 1.888 ± 0.02	3.297LeuAsn: 3.297 ± 0.026	5.838LeuPro: 5.838 ± 0.037	4.047LeuGln: 4.047 ± 0.036	5.503LeuArg: 5.503 ± 0.039	8.365LeuSer: 8.365 ± 0.05	5.226LeuThr: 5.226 ± 0.036	5.826LeuVal: 5.826 ± 0.043	1.236LeuTrp: 1.236 ± 0.016	2.586LeuTyr: 2.586 ± 0.022	0.0LeuXaa: 0.0 ± 0.0
Met	1.85MetAla: 1.85 ± 0.017	0.297MetCys: 0.297 ± 0.008	1.364MetAsp: 1.364 ± 0.019	1.29MetGlu: 1.29 ± 0.019	0.812MetPhe: 0.812 ± 0.013	1.323MetGly: 1.323 ± 0.019	0.63MetHis: 0.63 ± 0.013	1.065MetIle: 1.065 ± 0.017	1.125MetLys: 1.125 ± 0.015	1.958MetLeu: 1.958 ± 0.019	0.563MetMet: 0.563 ± 0.013	0.85MetAsn: 0.85 ± 0.014	1.199MetPro: 1.199 ± 0.018	0.903MetGln: 0.903 ± 0.015	1.339MetArg: 1.339 ± 0.017	2.193MetSer: 2.193 ± 0.021	1.322MetThr: 1.322 ± 0.018	1.328MetVal: 1.328 ± 0.018	0.306MetTrp: 0.306 ± 0.007	0.579MetTyr: 0.579 ± 0.012	0.0MetXaa: 0.0 ± 0.0
Asn	3.027AsnAla: 3.027 ± 0.029	0.513AsnCys: 0.513 ± 0.01	1.913AsnAsp: 1.913 ± 0.022	2.014AsnGlu: 2.014 ± 0.022	1.437AsnPhe: 1.437 ± 0.019	2.636AsnGly: 2.636 ± 0.027	0.968AsnHis: 0.968 ± 0.015	2.33AsnIle: 2.33 ± 0.022	1.729AsnLys: 1.729 ± 0.02	3.406AsnLeu: 3.406 ± 0.033	0.956AsnMet: 0.956 ± 0.014	1.623AsnAsn: 1.623 ± 0.02	2.385AsnPro: 2.385 ± 0.023	1.379AsnGln: 1.379 ± 0.018	1.796AsnArg: 1.796 ± 0.02	2.917AsnSer: 2.917 ± 0.024	2.282AsnThr: 2.282 ± 0.023	2.678AsnVal: 2.678 ± 0.026	0.589AsnTrp: 0.589 ± 0.012	1.079AsnTyr: 1.079 ± 0.015	0.0AsnXaa: 0.0 ± 0.0
Pro	4.425ProAla: 4.425 ± 0.038	0.572ProCys: 0.572 ± 0.012	3.0ProAsp: 3.0 ± 0.025	3.279ProGlu: 3.279 ± 0.03	2.166ProPhe: 2.166 ± 0.025	3.424ProGly: 3.424 ± 0.03	1.543ProHis: 1.543 ± 0.018	2.78ProIle: 2.78 ± 0.025	2.419ProLys: 2.419 ± 0.027	5.109ProLeu: 5.109 ± 0.036	1.058ProMet: 1.058 ± 0.016	2.152ProAsn: 2.152 ± 0.022	5.455ProPro: 5.455 ± 0.071	2.295ProGln: 2.295 ± 0.028	3.135ProArg: 3.135 ± 0.03	6.719ProSer: 6.719 ± 0.054	4.014ProThr: 4.014 ± 0.028	3.59ProVal: 3.59 ± 0.03	0.72ProTrp: 0.72 ± 0.014	1.67ProTyr: 1.67 ± 0.024	0.0ProXaa: 0.0 ± 0.0
Gln	3.306GlnAla: 3.306 ± 0.032	0.571GlnCys: 0.571 ± 0.013	2.038GlnAsp: 2.038 ± 0.02	2.237GlnGlu: 2.237 ± 0.024	1.322GlnPhe: 1.322 ± 0.017	2.481GlnGly: 2.481 ± 0.027	1.103GlnHis: 1.103 ± 0.017	2.068GlnIle: 2.068 ± 0.021	1.929GlnLys: 1.929 ± 0.021	3.569GlnLeu: 3.569 ± 0.031	0.89GlnMet: 0.89 ± 0.014	1.572GlnAsn: 1.572 ± 0.017	2.238GlnPro: 2.238 ± 0.028	2.009GlnGln: 2.009 ± 0.034	2.423GlnArg: 2.423 ± 0.024	3.214GlnSer: 3.214 ± 0.033	2.243GlnThr: 2.243 ± 0.024	2.297GlnVal: 2.297 ± 0.024	0.574GlnTrp: 0.574 ± 0.009	1.189GlnTyr: 1.189 ± 0.018	0.0GlnXaa: 0.0 ± 0.0
Arg	4.421ArgAla: 4.421 ± 0.035	0.776ArgCys: 0.776 ± 0.013	3.055ArgAsp: 3.055 ± 0.029	3.6ArgGlu: 3.6 ± 0.036	2.188ArgPhe: 2.188 ± 0.024	3.339ArgGly: 3.339 ± 0.031	1.55ArgHis: 1.55 ± 0.017	3.005ArgIle: 3.005 ± 0.028	3.313ArgLys: 3.313 ± 0.032	5.319ArgLeu: 5.319 ± 0.035	1.368ArgMet: 1.368 ± 0.016	2.153ArgAsn: 2.153 ± 0.022	3.118ArgPro: 3.118 ± 0.031	2.343ArgGln: 2.343 ± 0.023	4.546ArgArg: 4.546 ± 0.04	4.819ArgSer: 4.819 ± 0.044	3.325ArgThr: 3.325 ± 0.026	3.448ArgVal: 3.448 ± 0.029	0.927ArgTrp: 0.927 ± 0.015	1.637ArgTyr: 1.637 ± 0.019	0.0ArgXaa: 0.0 ± 0.0
Ser	6.446SerAla: 6.446 ± 0.043	1.046SerCys: 1.046 ± 0.015	4.432SerAsp: 4.432 ± 0.035	4.063SerGlu: 4.063 ± 0.034	3.357SerPhe: 3.357 ± 0.03	5.461SerGly: 5.461 ± 0.041	2.348SerHis: 2.348 ± 0.023	4.448SerIle: 4.448 ± 0.035	3.829SerLys: 3.829 ± 0.026	8.159SerLeu: 8.159 ± 0.053	1.84SerMet: 1.84 ± 0.021	3.197SerAsn: 3.197 ± 0.029	5.874SerPro: 5.874 ± 0.058	3.368SerGln: 3.368 ± 0.031	4.908SerArg: 4.908 ± 0.041	10.061SerSer: 10.061 ± 0.08	5.95SerThr: 5.95 ± 0.049	5.023SerVal: 5.023 ± 0.031	1.131SerTrp: 1.131 ± 0.016	2.259SerTyr: 2.259 ± 0.022	0.0SerXaa: 0.0 ± 0.0
Thr	4.643ThrAla: 4.643 ± 0.035	0.861ThrCys: 0.861 ± 0.015	2.708ThrAsp: 2.708 ± 0.025	2.811ThrGlu: 2.811 ± 0.026	2.403ThrPhe: 2.403 ± 0.024	3.805ThrGly: 3.805 ± 0.028	1.527ThrHis: 1.527 ± 0.018	3.207ThrIle: 3.207 ± 0.03	2.601ThrLys: 2.601 ± 0.027	5.782ThrLeu: 5.782 ± 0.042	1.274ThrMet: 1.274 ± 0.017	2.25ThrAsn: 2.25 ± 0.022	4.152ThrPro: 4.152 ± 0.038	2.166ThrGln: 2.166 ± 0.023	3.229ThrArg: 3.229 ± 0.027	5.73ThrSer: 5.73 ± 0.046	4.015ThrThr: 4.015 ± 0.037	3.761ThrVal: 3.761 ± 0.03	0.844ThrTrp: 0.844 ± 0.015	1.696ThrTyr: 1.696 ± 0.019	0.0ThrXaa: 0.0 ± 0.0
Val	4.985ValAla: 4.985 ± 0.045	0.861ValCys: 0.861 ± 0.015	3.778ValAsp: 3.778 ± 0.031	3.919ValGlu: 3.919 ± 0.029	2.584ValPhe: 2.584 ± 0.025	3.836ValGly: 3.836 ± 0.032	1.72ValHis: 1.72 ± 0.022	3.375ValIle: 3.375 ± 0.035	3.143ValLys: 3.143 ± 0.029	6.065ValLeu: 6.065 ± 0.033	1.362ValMet: 1.362 ± 0.017	2.389ValAsn: 2.389 ± 0.025	3.698ValPro: 3.698 ± 0.028	2.515ValGln: 2.515 ± 0.021	3.416ValArg: 3.416 ± 0.03	4.956ValSer: 4.956 ± 0.032	3.667ValThr: 3.667 ± 0.03	4.598ValVal: 4.598 ± 0.038	0.983ValTrp: 0.983 ± 0.018	1.816ValTyr: 1.816 ± 0.021	0.0ValXaa: 0.0 ± 0.0
Trp	1.101TrpAla: 1.101 ± 0.017	0.246TrpCys: 0.246 ± 0.007	0.947TrpAsp: 0.947 ± 0.016	0.864TrpGlu: 0.864 ± 0.015	0.563TrpPhe: 0.563 ± 0.011	0.871TrpGly: 0.871 ± 0.014	0.384TrpHis: 0.384 ± 0.009	0.857TrpIle: 0.857 ± 0.015	0.858TrpLys: 0.858 ± 0.014	1.364TrpLeu: 1.364 ± 0.018	0.393TrpMet: 0.393 ± 0.01	0.618TrpAsn: 0.618 ± 0.013	0.657TrpPro: 0.657 ± 0.013	0.536TrpGln: 0.536 ± 0.011	0.94TrpArg: 0.94 ± 0.014	1.165TrpSer: 1.165 ± 0.018	0.914TrpThr: 0.914 ± 0.013	0.893TrpVal: 0.893 ± 0.015	0.318TrpTrp: 0.318 ± 0.008	0.42TrpTyr: 0.42 ± 0.011	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.146TyrAla: 2.146 ± 0.024	0.463TyrCys: 0.463 ± 0.011	1.683TyrAsp: 1.683 ± 0.021	1.428TyrGlu: 1.428 ± 0.017	1.253TyrPhe: 1.253 ± 0.016	1.853TyrGly: 1.853 ± 0.022	0.814TyrHis: 0.814 ± 0.014	1.553TyrIle: 1.553 ± 0.021	1.215TyrLys: 1.215 ± 0.017	2.717TyrLeu: 2.717 ± 0.026	0.62TyrMet: 0.62 ± 0.012	1.262TyrAsn: 1.262 ± 0.017	1.594TyrPro: 1.594 ± 0.024	1.179TyrGln: 1.179 ± 0.016	1.578TyrArg: 1.578 ± 0.019	2.179TyrSer: 2.179 ± 0.021	1.778TyrThr: 1.778 ± 0.019	1.754TyrVal: 1.754 ± 0.019	0.416TyrTrp: 0.416 ± 0.01	0.927TyrTyr: 0.927 ± 0.014	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 14339 proteins (4645570 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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