Amino acid dipepetide frequency for Macaca fascicularis papillomavirus 8

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.3AlaAla: 6.3 ± 1.197
0.42AlaCys: 0.42 ± 0.383
4.2AlaAsp: 4.2 ± 0.983
3.78AlaGlu: 3.78 ± 1.159
1.26AlaPhe: 1.26 ± 0.639
7.14AlaGly: 7.14 ± 1.941
1.68AlaHis: 1.68 ± 0.971
2.94AlaIle: 2.94 ± 0.816
2.94AlaLys: 2.94 ± 1.158
5.88AlaLeu: 5.88 ± 1.586
2.52AlaMet: 2.52 ± 0.807
2.1AlaAsn: 2.1 ± 0.687
5.46AlaPro: 5.46 ± 2.221
2.94AlaGln: 2.94 ± 0.878
5.46AlaArg: 5.46 ± 1.256
3.78AlaSer: 3.78 ± 2.453
5.04AlaThr: 5.04 ± 1.693
3.78AlaVal: 3.78 ± 0.587
0.0AlaTrp: 0.0 ± 0.0
1.68AlaTyr: 1.68 ± 0.827
0.0AlaXaa: 0.0 ± 0.0
Cys
1.68CysAla: 1.68 ± 0.688
0.42CysCys: 0.42 ± 0.322
0.84CysAsp: 0.84 ± 0.436
2.1CysGlu: 2.1 ± 1.516
0.84CysPhe: 0.84 ± 0.657
1.68CysGly: 1.68 ± 1.007
0.42CysHis: 0.42 ± 0.569
1.26CysIle: 1.26 ± 0.534
2.52CysLys: 2.52 ± 0.866
4.2CysLeu: 4.2 ± 1.656
0.42CysMet: 0.42 ± 0.383
0.84CysAsn: 0.84 ± 0.367
2.1CysPro: 2.1 ± 0.672
1.68CysGln: 1.68 ± 1.149
1.26CysArg: 1.26 ± 0.746
2.52CysSer: 2.52 ± 1.376
0.84CysThr: 0.84 ± 0.581
1.68CysVal: 1.68 ± 0.685
1.26CysTrp: 1.26 ± 0.605
1.26CysTyr: 1.26 ± 0.777
0.0CysXaa: 0.0 ± 0.0
Asp
5.04AspAla: 5.04 ± 0.988
2.1AspCys: 2.1 ± 0.774
2.94AspAsp: 2.94 ± 1.009
4.2AspGlu: 4.2 ± 2.0
2.1AspPhe: 2.1 ± 0.643
2.94AspGly: 2.94 ± 0.816
0.84AspHis: 0.84 ± 0.436
3.36AspIle: 3.36 ± 1.627
1.68AspLys: 1.68 ± 0.855
6.3AspLeu: 6.3 ± 1.619
0.84AspMet: 0.84 ± 0.462
2.52AspAsn: 2.52 ± 0.657
3.36AspPro: 3.36 ± 1.321
1.26AspGln: 1.26 ± 0.611
2.1AspArg: 2.1 ± 0.848
4.2AspSer: 4.2 ± 1.688
4.2AspThr: 4.2 ± 0.837
3.78AspVal: 3.78 ± 1.489
1.68AspTrp: 1.68 ± 0.855
1.68AspTyr: 1.68 ± 0.831
0.0AspXaa: 0.0 ± 0.0
Glu
2.94GluAla: 2.94 ± 0.668
0.42GluCys: 0.42 ± 0.383
3.78GluAsp: 3.78 ± 1.908
5.04GluGlu: 5.04 ± 1.437
0.84GluPhe: 0.84 ± 0.436
4.62GluGly: 4.62 ± 1.758
0.84GluHis: 0.84 ± 0.462
1.68GluIle: 1.68 ± 1.223
1.26GluLys: 1.26 ± 0.799
2.52GluLeu: 2.52 ± 1.388
1.68GluMet: 1.68 ± 0.653
2.1GluAsn: 2.1 ± 0.687
3.78GluPro: 3.78 ± 0.604
2.52GluGln: 2.52 ± 1.385
2.1GluArg: 2.1 ± 0.999
4.62GluSer: 4.62 ± 1.424
6.72GluThr: 6.72 ± 1.625
4.2GluVal: 4.2 ± 1.479
0.42GluTrp: 0.42 ± 0.322
1.68GluTyr: 1.68 ± 1.038
0.0GluXaa: 0.0 ± 0.0
Phe
1.68PheAla: 1.68 ± 0.685
1.26PheCys: 1.26 ± 1.633
1.68PheAsp: 1.68 ± 0.653
0.0PheGlu: 0.0 ± 0.0
2.1PhePhe: 2.1 ± 0.678
3.36PheGly: 3.36 ± 0.718
0.84PheHis: 0.84 ± 0.58
0.42PheIle: 0.42 ± 0.322
2.1PheLys: 2.1 ± 0.828
6.72PheLeu: 6.72 ± 1.511
0.84PheMet: 0.84 ± 0.407
0.84PheAsn: 0.84 ± 0.766
0.84PhePro: 0.84 ± 0.367
1.68PheGln: 1.68 ± 0.734
0.84PheArg: 0.84 ± 0.367
2.52PheSer: 2.52 ± 0.611
0.42PheThr: 0.42 ± 0.351
2.94PheVal: 2.94 ± 0.864
1.26PheTrp: 1.26 ± 0.534
0.84PheTyr: 0.84 ± 0.426
0.0PheXaa: 0.0 ± 0.0
Gly
3.78GlyAla: 3.78 ± 0.881
2.1GlyCys: 2.1 ± 0.689
5.46GlyAsp: 5.46 ± 1.417
4.62GlyGlu: 4.62 ± 1.221
0.84GlyPhe: 0.84 ± 0.407
5.46GlyGly: 5.46 ± 1.923
2.52GlyHis: 2.52 ± 1.206
2.94GlyIle: 2.94 ± 1.004
2.94GlyLys: 2.94 ± 0.924
5.04GlyLeu: 5.04 ± 1.562
2.1GlyMet: 2.1 ± 0.696
1.68GlyAsn: 1.68 ± 0.855
2.94GlyPro: 2.94 ± 0.881
1.68GlyGln: 1.68 ± 1.038
3.78GlyArg: 3.78 ± 1.253
5.88GlySer: 5.88 ± 0.915
5.04GlyThr: 5.04 ± 1.313
5.88GlyVal: 5.88 ± 1.067
0.84GlyTrp: 0.84 ± 0.436
1.68GlyTyr: 1.68 ± 0.316
0.0GlyXaa: 0.0 ± 0.0
His
2.52HisAla: 2.52 ± 0.737
1.68HisCys: 1.68 ± 1.399
0.84HisAsp: 0.84 ± 0.611
1.68HisGlu: 1.68 ± 1.064
0.84HisPhe: 0.84 ± 0.407
1.68HisGly: 1.68 ± 0.717
1.68HisHis: 1.68 ± 0.811
1.26HisIle: 1.26 ± 0.46
0.84HisLys: 0.84 ± 0.407
1.68HisLeu: 1.68 ± 0.991
0.84HisMet: 0.84 ± 0.367
1.68HisAsn: 1.68 ± 0.656
2.1HisPro: 2.1 ± 0.98
1.26HisGln: 1.26 ± 0.622
0.42HisArg: 0.42 ± 0.351
3.36HisSer: 3.36 ± 0.609
0.84HisThr: 0.84 ± 0.459
3.36HisVal: 3.36 ± 0.866
1.26HisTrp: 1.26 ± 0.728
0.42HisTyr: 0.42 ± 0.322
0.0HisXaa: 0.0 ± 0.0
Ile
2.52IleAla: 2.52 ± 1.039
1.26IleCys: 1.26 ± 0.952
2.52IleAsp: 2.52 ± 1.288
2.1IleGlu: 2.1 ± 0.83
0.42IlePhe: 0.42 ± 0.383
2.94IleGly: 2.94 ± 0.854
1.26IleHis: 1.26 ± 0.676
0.84IleIle: 0.84 ± 0.58
0.84IleLys: 0.84 ± 0.367
3.36IleLeu: 3.36 ± 0.664
0.42IleMet: 0.42 ± 0.286
0.42IleAsn: 0.42 ± 0.383
2.52IlePro: 2.52 ± 1.148
0.84IleGln: 0.84 ± 0.367
1.26IleArg: 1.26 ± 0.656
2.94IleSer: 2.94 ± 0.636
4.2IleThr: 4.2 ± 1.118
5.46IleVal: 5.46 ± 1.983
0.0IleTrp: 0.0 ± 0.0
1.68IleTyr: 1.68 ± 0.742
0.0IleXaa: 0.0 ± 0.0
Lys
2.52LysAla: 2.52 ± 1.341
2.1LysCys: 2.1 ± 1.277
0.84LysAsp: 0.84 ± 0.436
2.1LysGlu: 2.1 ± 0.753
2.94LysPhe: 2.94 ± 1.26
1.68LysGly: 1.68 ± 0.656
1.26LysHis: 1.26 ± 0.681
1.68LysIle: 1.68 ± 0.925
3.78LysLys: 3.78 ± 2.124
2.52LysLeu: 2.52 ± 1.21
0.42LysMet: 0.42 ± 0.383
1.26LysAsn: 1.26 ± 0.574
2.52LysPro: 2.52 ± 0.793
2.52LysGln: 2.52 ± 1.163
4.62LysArg: 4.62 ± 1.146
3.36LysSer: 3.36 ± 1.395
2.52LysThr: 2.52 ± 0.849
3.78LysVal: 3.78 ± 0.763
0.0LysTrp: 0.0 ± 0.0
2.94LysTyr: 2.94 ± 0.946
0.0LysXaa: 0.0 ± 0.0
Leu
3.78LeuAla: 3.78 ± 0.694
3.78LeuCys: 3.78 ± 2.533
5.88LeuAsp: 5.88 ± 1.066
5.46LeuGlu: 5.46 ± 1.468
5.04LeuPhe: 5.04 ± 3.031
4.2LeuGly: 4.2 ± 1.579
3.78LeuHis: 3.78 ± 1.476
2.52LeuIle: 2.52 ± 0.824
5.04LeuLys: 5.04 ± 1.631
9.66LeuLeu: 9.66 ± 4.227
1.68LeuMet: 1.68 ± 0.851
3.78LeuAsn: 3.78 ± 1.041
5.04LeuPro: 5.04 ± 1.969
7.56LeuGln: 7.56 ± 2.43
5.46LeuArg: 5.46 ± 2.374
4.2LeuSer: 4.2 ± 1.317
2.52LeuThr: 2.52 ± 0.696
3.78LeuVal: 3.78 ± 1.232
1.26LeuTrp: 1.26 ± 0.46
5.04LeuTyr: 5.04 ± 1.62
0.0LeuXaa: 0.0 ± 0.0
Met
1.26MetAla: 1.26 ± 0.46
0.42MetCys: 0.42 ± 0.322
2.1MetAsp: 2.1 ± 0.601
0.84MetGlu: 0.84 ± 0.407
0.84MetPhe: 0.84 ± 0.766
1.68MetGly: 1.68 ± 0.501
0.84MetHis: 0.84 ± 0.436
0.84MetIle: 0.84 ± 0.543
1.26MetLys: 1.26 ± 0.574
2.52MetLeu: 2.52 ± 1.269
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
0.84MetPro: 0.84 ± 0.611
2.1MetGln: 2.1 ± 0.798
0.42MetArg: 0.42 ± 0.322
4.2MetSer: 4.2 ± 1.307
0.84MetThr: 0.84 ± 0.459
1.68MetVal: 1.68 ± 0.734
0.42MetTrp: 0.42 ± 0.353
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.36AsnAla: 3.36 ± 1.04
0.84AsnCys: 0.84 ± 0.543
2.52AsnAsp: 2.52 ± 1.121
0.42AsnGlu: 0.42 ± 0.552
1.26AsnPhe: 1.26 ± 1.149
2.1AsnGly: 2.1 ± 0.608
0.42AsnHis: 0.42 ± 0.353
1.26AsnIle: 1.26 ± 0.847
2.94AsnLys: 2.94 ± 1.931
0.0AsnLeu: 0.0 ± 0.0
0.42AsnMet: 0.42 ± 0.383
0.84AsnAsn: 0.84 ± 0.766
2.1AsnPro: 2.1 ± 0.633
0.84AsnGln: 0.84 ± 0.367
1.68AsnArg: 1.68 ± 0.734
1.26AsnSer: 1.26 ± 0.405
3.36AsnThr: 3.36 ± 1.096
1.68AsnVal: 1.68 ± 0.971
0.42AsnTrp: 0.42 ± 0.322
0.84AsnTyr: 0.84 ± 0.644
0.0AsnXaa: 0.0 ± 0.0
Pro
7.14ProAla: 7.14 ± 2.498
1.68ProCys: 1.68 ± 0.685
5.46ProAsp: 5.46 ± 2.049
2.52ProGlu: 2.52 ± 0.935
2.1ProPhe: 2.1 ± 1.03
2.1ProGly: 2.1 ± 0.694
2.1ProHis: 2.1 ± 0.643
2.1ProIle: 2.1 ± 1.003
3.36ProLys: 3.36 ± 0.957
8.4ProLeu: 8.4 ± 2.119
1.26ProMet: 1.26 ± 0.689
1.68ProAsn: 1.68 ± 1.064
7.98ProPro: 7.98 ± 2.071
2.1ProGln: 2.1 ± 0.999
2.52ProArg: 2.52 ± 1.331
3.36ProSer: 3.36 ± 1.148
5.04ProThr: 5.04 ± 1.705
3.78ProVal: 3.78 ± 1.014
0.84ProTrp: 0.84 ± 0.626
2.1ProTyr: 2.1 ± 0.935
0.0ProXaa: 0.0 ± 0.0
Gln
2.1GlnAla: 2.1 ± 0.908
1.26GlnCys: 1.26 ± 0.802
2.52GlnAsp: 2.52 ± 0.955
2.1GlnGlu: 2.1 ± 0.999
2.94GlnPhe: 2.94 ± 0.668
2.94GlnGly: 2.94 ± 0.931
0.84GlnHis: 0.84 ± 0.581
0.84GlnIle: 0.84 ± 0.459
1.26GlnLys: 1.26 ± 0.952
2.94GlnLeu: 2.94 ± 1.049
2.52GlnMet: 2.52 ± 0.849
0.42GlnAsn: 0.42 ± 0.322
4.2GlnPro: 4.2 ± 0.829
2.94GlnGln: 2.94 ± 1.187
3.36GlnArg: 3.36 ± 1.933
0.42GlnSer: 0.42 ± 0.383
3.78GlnThr: 3.78 ± 1.531
3.36GlnVal: 3.36 ± 1.066
0.84GlnTrp: 0.84 ± 0.644
0.84GlnTyr: 0.84 ± 0.367
0.0GlnXaa: 0.0 ± 0.0
Arg
7.56ArgAla: 7.56 ± 1.464
2.52ArgCys: 2.52 ± 2.223
2.1ArgAsp: 2.1 ± 0.789
2.1ArgGlu: 2.1 ± 1.294
1.68ArgPhe: 1.68 ± 0.607
2.1ArgGly: 2.1 ± 0.75
2.1ArgHis: 2.1 ± 0.753
1.68ArgIle: 1.68 ± 1.035
2.52ArgLys: 2.52 ± 0.898
7.56ArgLeu: 7.56 ± 1.595
0.42ArgMet: 0.42 ± 0.363
0.84ArgAsn: 0.84 ± 0.58
4.2ArgPro: 4.2 ± 1.906
1.26ArgGln: 1.26 ± 0.681
5.88ArgArg: 5.88 ± 2.103
2.52ArgSer: 2.52 ± 0.628
3.36ArgThr: 3.36 ± 0.918
4.2ArgVal: 4.2 ± 1.235
1.68ArgTrp: 1.68 ± 0.767
1.68ArgTyr: 1.68 ± 0.897
0.0ArgXaa: 0.0 ± 0.0
Ser
3.36SerAla: 3.36 ± 1.41
1.68SerCys: 1.68 ± 0.754
2.52SerAsp: 2.52 ± 0.413
3.78SerGlu: 3.78 ± 0.757
1.26SerPhe: 1.26 ± 0.681
5.46SerGly: 5.46 ± 0.785
1.26SerHis: 1.26 ± 0.329
2.52SerIle: 2.52 ± 1.046
2.94SerLys: 2.94 ± 1.094
6.72SerLeu: 6.72 ± 1.324
2.52SerMet: 2.52 ± 0.766
3.78SerAsn: 3.78 ± 1.348
5.04SerPro: 5.04 ± 0.951
2.52SerGln: 2.52 ± 1.27
4.2SerArg: 4.2 ± 1.491
7.14SerSer: 7.14 ± 2.135
6.72SerThr: 6.72 ± 1.788
5.88SerVal: 5.88 ± 2.092
0.84SerTrp: 0.84 ± 0.611
1.68SerTyr: 1.68 ± 0.491
0.0SerXaa: 0.0 ± 0.0
Thr
5.04ThrAla: 5.04 ± 0.683
2.52ThrCys: 2.52 ± 0.564
3.36ThrAsp: 3.36 ± 0.744
2.94ThrGlu: 2.94 ± 1.148
1.68ThrPhe: 1.68 ± 0.573
4.2ThrGly: 4.2 ± 1.126
1.26ThrHis: 1.26 ± 0.606
3.78ThrIle: 3.78 ± 1.455
0.84ThrLys: 0.84 ± 0.58
5.46ThrLeu: 5.46 ± 1.636
0.84ThrMet: 0.84 ± 0.644
1.68ThrAsn: 1.68 ± 1.038
6.3ThrPro: 6.3 ± 1.949
2.94ThrGln: 2.94 ± 0.668
3.78ThrArg: 3.78 ± 1.296
7.56ThrSer: 7.56 ± 2.173
2.94ThrThr: 2.94 ± 1.495
5.46ThrVal: 5.46 ± 1.413
0.84ThrTrp: 0.84 ± 0.436
4.62ThrTyr: 4.62 ± 0.985
0.0ThrXaa: 0.0 ± 0.0
Val
3.78ValAla: 3.78 ± 1.316
1.68ValCys: 1.68 ± 0.922
4.2ValAsp: 4.2 ± 0.98
5.46ValGlu: 5.46 ± 1.239
2.94ValPhe: 2.94 ± 0.864
4.62ValGly: 4.62 ± 0.897
3.36ValHis: 3.36 ± 1.201
2.94ValIle: 2.94 ± 0.518
2.52ValLys: 2.52 ± 0.77
5.04ValLeu: 5.04 ± 1.808
1.68ValMet: 1.68 ± 0.809
1.26ValAsn: 1.26 ± 0.464
4.2ValPro: 4.2 ± 1.303
2.52ValGln: 2.52 ± 0.766
5.04ValArg: 5.04 ± 0.772
6.3ValSer: 6.3 ± 0.877
5.46ValThr: 5.46 ± 0.89
5.88ValVal: 5.88 ± 1.732
0.42ValTrp: 0.42 ± 0.383
4.62ValTyr: 4.62 ± 2.506
0.0ValXaa: 0.0 ± 0.0
Trp
0.84TrpAla: 0.84 ± 0.367
0.42TrpCys: 0.42 ± 0.322
0.42TrpAsp: 0.42 ± 0.383
0.42TrpGlu: 0.42 ± 0.353
0.42TrpPhe: 0.42 ± 0.322
1.68TrpGly: 1.68 ± 0.83
1.26TrpHis: 1.26 ± 0.74
0.84TrpIle: 0.84 ± 0.644
1.26TrpLys: 1.26 ± 0.965
0.84TrpLeu: 0.84 ± 0.367
0.42TrpMet: 0.42 ± 0.569
0.84TrpAsn: 0.84 ± 0.367
0.84TrpPro: 0.84 ± 0.407
0.0TrpGln: 0.0 ± 0.0
0.84TrpArg: 0.84 ± 0.462
0.42TrpSer: 0.42 ± 0.569
2.1TrpThr: 2.1 ± 1.466
0.84TrpVal: 0.84 ± 0.564
0.0TrpTrp: 0.0 ± 0.0
0.84TrpTyr: 0.84 ± 0.407
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.1TyrAla: 2.1 ± 0.582
1.26TyrCys: 1.26 ± 0.777
2.94TyrAsp: 2.94 ± 1.135
2.1TyrGlu: 2.1 ± 0.798
0.84TyrPhe: 0.84 ± 0.407
4.62TyrGly: 4.62 ± 0.577
1.68TyrHis: 1.68 ± 0.608
2.1TyrIle: 2.1 ± 1.158
2.52TyrLys: 2.52 ± 1.059
2.1TyrLeu: 2.1 ± 1.02
0.84TyrMet: 0.84 ± 0.644
0.0TyrAsn: 0.0 ± 0.0
1.26TyrPro: 1.26 ± 0.605
1.26TyrGln: 1.26 ± 0.689
3.36TyrArg: 3.36 ± 1.09
1.26TyrSer: 1.26 ± 0.738
2.1TyrThr: 2.1 ± 1.166
2.52TyrVal: 2.52 ± 0.632
1.26TyrTrp: 1.26 ± 0.329
1.68TyrTyr: 1.68 ± 0.925
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 8 proteins (2382 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski