Amino acid dipepetide frequency for Soybean chlorotic mottle virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
0.379AlaAla: 0.379 ± 0.33
0.379AlaCys: 0.379 ± 0.495
2.274AlaAsp: 2.274 ± 0.927
3.412AlaGlu: 3.412 ± 1.556
1.895AlaPhe: 1.895 ± 0.513
0.758AlaGly: 0.758 ± 0.551
1.137AlaHis: 1.137 ± 0.688
2.274AlaIle: 2.274 ± 0.921
3.033AlaLys: 3.033 ± 1.491
3.412AlaLeu: 3.412 ± 0.937
0.0AlaMet: 0.0 ± 0.0
1.516AlaAsn: 1.516 ± 0.647
1.137AlaPro: 1.137 ± 0.677
1.137AlaGln: 1.137 ± 0.624
0.379AlaArg: 0.379 ± 0.436
4.549AlaSer: 4.549 ± 1.355
2.654AlaThr: 2.654 ± 0.965
1.516AlaVal: 1.516 ± 1.017
0.0AlaTrp: 0.0 ± 0.0
3.033AlaTyr: 3.033 ± 0.899
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
1.137CysCys: 1.137 ± 0.997
0.0CysAsp: 0.0 ± 0.0
2.654CysGlu: 2.654 ± 0.943
0.379CysPhe: 0.379 ± 0.275
0.0CysGly: 0.0 ± 0.0
0.758CysHis: 0.758 ± 0.367
0.758CysIle: 0.758 ± 0.495
0.758CysLys: 0.758 ± 0.495
3.791CysLeu: 3.791 ± 1.153
0.0CysMet: 0.0 ± 0.0
0.758CysAsn: 0.758 ± 0.66
1.137CysPro: 1.137 ± 0.641
1.137CysGln: 1.137 ± 0.546
0.758CysArg: 0.758 ± 0.367
1.137CysSer: 1.137 ± 0.429
0.379CysThr: 0.379 ± 0.275
0.379CysVal: 0.379 ± 0.33
0.379CysTrp: 0.379 ± 0.33
0.379CysTyr: 0.379 ± 0.33
0.0CysXaa: 0.0 ± 0.0
Asp
1.516AspAla: 1.516 ± 0.578
1.137AspCys: 1.137 ± 0.546
1.895AspAsp: 1.895 ± 0.607
6.444AspGlu: 6.444 ± 1.504
3.791AspPhe: 3.791 ± 1.141
1.516AspGly: 1.516 ± 0.778
0.0AspHis: 0.0 ± 0.0
1.895AspIle: 1.895 ± 0.678
3.791AspLys: 3.791 ± 1.284
5.307AspLeu: 5.307 ± 1.418
0.379AspMet: 0.379 ± 0.495
2.654AspAsn: 2.654 ± 1.094
0.758AspPro: 0.758 ± 0.408
2.274AspGln: 2.274 ± 1.026
1.895AspArg: 1.895 ± 0.607
3.033AspSer: 3.033 ± 1.066
3.791AspThr: 3.791 ± 1.429
1.516AspVal: 1.516 ± 0.786
1.137AspTrp: 1.137 ± 0.555
0.379AspTyr: 0.379 ± 0.275
0.0AspXaa: 0.0 ± 0.0
Glu
3.033GluAla: 3.033 ± 1.231
1.137GluCys: 1.137 ± 0.506
3.791GluAsp: 3.791 ± 1.156
10.993GluGlu: 10.993 ± 2.583
4.549GluPhe: 4.549 ± 0.786
1.895GluGly: 1.895 ± 0.406
1.516GluHis: 1.516 ± 0.651
7.582GluIle: 7.582 ± 1.622
10.235GluLys: 10.235 ± 2.478
11.372GluLeu: 11.372 ± 1.564
0.379GluMet: 0.379 ± 0.427
7.202GluAsn: 7.202 ± 0.905
1.895GluPro: 1.895 ± 1.097
5.307GluGln: 5.307 ± 1.71
1.516GluArg: 1.516 ± 0.701
5.307GluSer: 5.307 ± 1.194
6.065GluThr: 6.065 ± 1.598
4.549GluVal: 4.549 ± 0.948
1.895GluTrp: 1.895 ± 0.616
2.654GluTyr: 2.654 ± 0.854
0.0GluXaa: 0.0 ± 0.0
Phe
1.516PheAla: 1.516 ± 0.816
0.379PheCys: 0.379 ± 0.275
3.791PheAsp: 3.791 ± 1.618
3.033PheGlu: 3.033 ± 0.984
1.137PhePhe: 1.137 ± 0.603
1.516PheGly: 1.516 ± 0.816
0.0PheHis: 0.0 ± 0.0
2.274PheIle: 2.274 ± 0.927
6.065PheLys: 6.065 ± 2.17
6.823PheLeu: 6.823 ± 2.189
0.758PheMet: 0.758 ± 0.424
1.895PheAsn: 1.895 ± 0.826
1.516PhePro: 1.516 ± 0.767
0.379PheGln: 0.379 ± 0.33
1.516PheArg: 1.516 ± 1.017
4.549PheSer: 4.549 ± 1.59
1.137PheThr: 1.137 ± 0.558
0.379PheVal: 0.379 ± 0.33
0.379PheTrp: 0.379 ± 0.33
2.654PheTyr: 2.654 ± 1.245
0.0PheXaa: 0.0 ± 0.0
Gly
1.516GlyAla: 1.516 ± 0.665
1.137GlyCys: 1.137 ± 0.558
0.758GlyAsp: 0.758 ± 0.48
1.137GlyGlu: 1.137 ± 0.541
1.895GlyPhe: 1.895 ± 0.769
1.516GlyGly: 1.516 ± 1.026
0.758GlyHis: 0.758 ± 0.437
4.928GlyIle: 4.928 ± 1.291
5.307GlyLys: 5.307 ± 1.518
4.928GlyLeu: 4.928 ± 1.724
0.0GlyMet: 0.0 ± 0.0
3.033GlyAsn: 3.033 ± 1.369
1.137GlyPro: 1.137 ± 0.814
0.758GlyGln: 0.758 ± 0.695
1.516GlyArg: 1.516 ± 0.696
1.895GlySer: 1.895 ± 0.819
1.895GlyThr: 1.895 ± 0.883
1.137GlyVal: 1.137 ± 0.489
0.0GlyTrp: 0.0 ± 0.0
1.516GlyTyr: 1.516 ± 0.702
0.0GlyXaa: 0.0 ± 0.0
His
1.137HisAla: 1.137 ± 0.576
0.0HisCys: 0.0 ± 0.0
0.379HisAsp: 0.379 ± 0.275
2.274HisGlu: 2.274 ± 0.595
0.0HisPhe: 0.0 ± 0.0
0.758HisGly: 0.758 ± 0.461
0.758HisHis: 0.758 ± 0.437
2.274HisIle: 2.274 ± 0.897
1.137HisLys: 1.137 ± 0.814
1.895HisLeu: 1.895 ± 0.962
0.0HisMet: 0.0 ± 0.0
0.758HisAsn: 0.758 ± 0.495
1.137HisPro: 1.137 ± 0.618
1.516HisGln: 1.516 ± 0.821
0.758HisArg: 0.758 ± 0.408
2.274HisSer: 2.274 ± 0.676
0.758HisThr: 0.758 ± 0.495
0.758HisVal: 0.758 ± 0.551
0.0HisTrp: 0.0 ± 0.0
1.516HisTyr: 1.516 ± 0.593
0.0HisXaa: 0.0 ± 0.0
Ile
1.895IleAla: 1.895 ± 0.736
1.895IleCys: 1.895 ± 0.656
4.549IleAsp: 4.549 ± 1.358
7.582IleGlu: 7.582 ± 1.531
2.654IlePhe: 2.654 ± 0.943
3.412IleGly: 3.412 ± 1.071
1.137IleHis: 1.137 ± 0.706
6.065IleIle: 6.065 ± 1.658
7.961IleLys: 7.961 ± 1.237
5.307IleLeu: 5.307 ± 1.976
1.137IleMet: 1.137 ± 0.57
6.065IleAsn: 6.065 ± 0.939
3.033IlePro: 3.033 ± 0.763
4.17IleGln: 4.17 ± 1.465
4.17IleArg: 4.17 ± 1.311
6.823IleSer: 6.823 ± 2.025
3.033IleThr: 3.033 ± 1.035
3.412IleVal: 3.412 ± 0.854
0.0IleTrp: 0.0 ± 0.0
3.033IleTyr: 3.033 ± 0.583
0.0IleXaa: 0.0 ± 0.0
Lys
3.033LysAla: 3.033 ± 1.645
0.758LysCys: 0.758 ± 0.367
3.412LysAsp: 3.412 ± 1.319
10.235LysGlu: 10.235 ± 2.327
2.274LysPhe: 2.274 ± 1.55
6.065LysGly: 6.065 ± 2.525
2.654LysHis: 2.654 ± 0.957
12.889LysIle: 12.889 ± 1.608
12.509LysLys: 12.509 ± 3.78
9.856LysLeu: 9.856 ± 1.541
2.274LysMet: 2.274 ± 1.017
7.582LysAsn: 7.582 ± 1.737
3.033LysPro: 3.033 ± 1.011
8.34LysGln: 8.34 ± 1.348
6.065LysArg: 6.065 ± 3.368
7.202LysSer: 7.202 ± 1.33
6.444LysThr: 6.444 ± 1.483
3.412LysVal: 3.412 ± 0.836
1.137LysTrp: 1.137 ± 0.558
3.033LysTyr: 3.033 ± 0.932
0.0LysXaa: 0.0 ± 0.0
Leu
4.17LeuAla: 4.17 ± 0.85
3.412LeuCys: 3.412 ± 1.019
8.34LeuAsp: 8.34 ± 1.755
12.13LeuGlu: 12.13 ± 2.109
1.895LeuPhe: 1.895 ± 0.498
5.307LeuGly: 5.307 ± 1.22
1.516LeuHis: 1.516 ± 0.565
7.582LeuIle: 7.582 ± 1.87
11.372LeuLys: 11.372 ± 2.901
7.202LeuLeu: 7.202 ± 1.125
1.516LeuMet: 1.516 ± 0.548
4.17LeuAsn: 4.17 ± 1.742
4.17LeuPro: 4.17 ± 0.914
4.928LeuGln: 4.928 ± 1.347
6.065LeuArg: 6.065 ± 1.602
8.719LeuSer: 8.719 ± 1.878
6.444LeuThr: 6.444 ± 0.962
2.274LeuVal: 2.274 ± 1.102
0.758LeuTrp: 0.758 ± 0.367
2.274LeuTyr: 2.274 ± 0.493
0.0LeuXaa: 0.0 ± 0.0
Met
0.379MetAla: 0.379 ± 0.33
0.379MetCys: 0.379 ± 0.33
0.758MetAsp: 0.758 ± 0.565
1.516MetGlu: 1.516 ± 0.668
0.0MetPhe: 0.0 ± 0.0
0.0MetGly: 0.0 ± 0.0
0.379MetHis: 0.379 ± 0.348
1.137MetIle: 1.137 ± 0.444
1.516MetLys: 1.516 ± 0.921
1.516MetLeu: 1.516 ± 0.963
0.0MetMet: 0.0 ± 0.0
1.516MetAsn: 1.516 ± 0.565
0.379MetPro: 0.379 ± 0.436
0.0MetGln: 0.0 ± 0.0
0.758MetArg: 0.758 ± 0.728
0.758MetSer: 0.758 ± 0.728
0.758MetThr: 0.758 ± 0.595
1.137MetVal: 1.137 ± 0.603
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.516AsnAla: 1.516 ± 0.544
0.758AsnCys: 0.758 ± 0.686
1.516AsnAsp: 1.516 ± 0.663
4.17AsnGlu: 4.17 ± 1.303
4.928AsnPhe: 4.928 ± 0.731
2.274AsnGly: 2.274 ± 0.881
1.516AsnHis: 1.516 ± 0.53
1.516AsnIle: 1.516 ± 0.826
5.686AsnLys: 5.686 ± 1.666
7.582AsnLeu: 7.582 ± 1.851
1.137AsnMet: 1.137 ± 0.664
4.17AsnAsn: 4.17 ± 0.791
4.549AsnPro: 4.549 ± 1.386
4.928AsnGln: 4.928 ± 1.782
2.274AsnArg: 2.274 ± 0.928
4.549AsnSer: 4.549 ± 1.529
3.033AsnThr: 3.033 ± 1.088
3.791AsnVal: 3.791 ± 1.22
1.137AsnTrp: 1.137 ± 0.544
2.654AsnTyr: 2.654 ± 0.746
0.0AsnXaa: 0.0 ± 0.0
Pro
2.654ProAla: 2.654 ± 0.766
0.0ProCys: 0.0 ± 0.0
1.137ProAsp: 1.137 ± 0.706
2.654ProGlu: 2.654 ± 1.333
1.137ProPhe: 1.137 ± 0.558
0.379ProGly: 0.379 ± 0.436
2.274ProHis: 2.274 ± 1.04
3.412ProIle: 3.412 ± 1.014
5.307ProLys: 5.307 ± 1.046
2.654ProLeu: 2.654 ± 1.148
0.0ProMet: 0.0 ± 0.511
1.895ProAsn: 1.895 ± 1.041
2.274ProPro: 2.274 ± 1.247
1.137ProGln: 1.137 ± 0.637
2.274ProArg: 2.274 ± 1.076
1.895ProSer: 1.895 ± 0.577
1.137ProThr: 1.137 ± 0.494
1.895ProVal: 1.895 ± 0.81
1.137ProTrp: 1.137 ± 0.55
1.895ProTyr: 1.895 ± 0.639
0.0ProXaa: 0.0 ± 0.0
Gln
2.654GlnAla: 2.654 ± 1.045
0.758GlnCys: 0.758 ± 0.66
1.895GlnAsp: 1.895 ± 0.636
4.17GlnGlu: 4.17 ± 0.897
0.758GlnPhe: 0.758 ± 0.495
0.758GlnGly: 0.758 ± 0.495
1.516GlnHis: 1.516 ± 0.565
3.791GlnIle: 3.791 ± 1.229
5.686GlnLys: 5.686 ± 1.068
6.444GlnLeu: 6.444 ± 2.037
0.379GlnMet: 0.379 ± 0.275
3.412GlnAsn: 3.412 ± 1.576
3.033GlnPro: 3.033 ± 0.87
4.549GlnGln: 4.549 ± 1.561
2.274GlnArg: 2.274 ± 0.981
3.791GlnSer: 3.791 ± 0.721
3.412GlnThr: 3.412 ± 1.119
2.654GlnVal: 2.654 ± 1.017
0.0GlnTrp: 0.0 ± 0.0
1.516GlnTyr: 1.516 ± 0.718
0.0GlnXaa: 0.0 ± 0.0
Arg
0.758ArgAla: 0.758 ± 0.367
0.0ArgCys: 0.0 ± 0.0
1.895ArgAsp: 1.895 ± 1.115
3.412ArgGlu: 3.412 ± 1.141
2.654ArgPhe: 2.654 ± 0.998
0.758ArgGly: 0.758 ± 0.367
0.0ArgHis: 0.0 ± 0.0
4.928ArgIle: 4.928 ± 1.322
4.928ArgLys: 4.928 ± 2.219
5.307ArgLeu: 5.307 ± 1.685
0.758ArgMet: 0.758 ± 0.565
4.928ArgAsn: 4.928 ± 2.345
0.758ArgPro: 0.758 ± 0.66
1.137ArgGln: 1.137 ± 0.52
3.412ArgArg: 3.412 ± 1.098
1.137ArgSer: 1.137 ± 0.592
1.895ArgThr: 1.895 ± 0.573
0.379ArgVal: 0.379 ± 0.275
1.516ArgTrp: 1.516 ± 0.723
3.033ArgTyr: 3.033 ± 0.577
0.0ArgXaa: 0.0 ± 0.0
Ser
3.791SerAla: 3.791 ± 1.025
0.758SerCys: 0.758 ± 0.408
3.033SerAsp: 3.033 ± 0.945
7.202SerGlu: 7.202 ± 2.602
3.033SerPhe: 3.033 ± 0.842
3.791SerGly: 3.791 ± 1.242
1.516SerHis: 1.516 ± 0.723
4.549SerIle: 4.549 ± 1.047
8.719SerLys: 8.719 ± 1.306
4.928SerLeu: 4.928 ± 0.819
1.516SerMet: 1.516 ± 0.507
5.686SerAsn: 5.686 ± 1.186
2.274SerPro: 2.274 ± 1.04
2.274SerGln: 2.274 ± 0.676
2.274SerArg: 2.274 ± 0.767
7.582SerSer: 7.582 ± 1.575
3.412SerThr: 3.412 ± 1.203
3.412SerVal: 3.412 ± 1.072
0.758SerTrp: 0.758 ± 0.443
2.274SerTyr: 2.274 ± 0.766
0.0SerXaa: 0.0 ± 0.0
Thr
1.137ThrAla: 1.137 ± 0.558
1.137ThrCys: 1.137 ± 0.714
3.033ThrAsp: 3.033 ± 1.089
4.928ThrGlu: 4.928 ± 0.962
2.274ThrPhe: 2.274 ± 0.599
2.274ThrGly: 2.274 ± 0.508
1.137ThrHis: 1.137 ± 0.564
4.17ThrIle: 4.17 ± 0.959
8.34ThrLys: 8.34 ± 1.995
6.823ThrLeu: 6.823 ± 1.368
1.137ThrMet: 1.137 ± 0.753
1.516ThrAsn: 1.516 ± 0.611
0.379ThrPro: 0.379 ± 0.405
2.274ThrGln: 2.274 ± 0.81
2.654ThrArg: 2.654 ± 0.976
3.412ThrSer: 3.412 ± 1.681
1.895ThrThr: 1.895 ± 0.813
1.895ThrVal: 1.895 ± 1.001
0.379ThrTrp: 0.379 ± 0.348
0.379ThrTyr: 0.379 ± 0.348
0.0ThrXaa: 0.0 ± 0.0
Val
1.516ValAla: 1.516 ± 0.448
0.758ValCys: 0.758 ± 0.408
1.895ValAsp: 1.895 ± 0.812
3.791ValGlu: 3.791 ± 0.681
3.412ValPhe: 3.412 ± 1.9
2.274ValGly: 2.274 ± 1.297
0.379ValHis: 0.379 ± 0.405
1.895ValIle: 1.895 ± 0.647
4.549ValLys: 4.549 ± 1.276
4.928ValLeu: 4.928 ± 1.08
0.379ValMet: 0.379 ± 0.348
1.895ValAsn: 1.895 ± 0.953
2.274ValPro: 2.274 ± 0.816
2.274ValGln: 2.274 ± 0.933
1.137ValArg: 1.137 ± 0.505
2.274ValSer: 2.274 ± 1.119
1.516ValThr: 1.516 ± 0.816
0.379ValVal: 0.379 ± 0.405
0.0ValTrp: 0.0 ± 0.0
0.758ValTyr: 0.758 ± 0.66
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.379TrpCys: 0.379 ± 0.436
0.379TrpAsp: 0.379 ± 0.275
0.379TrpGlu: 0.379 ± 0.275
0.758TrpPhe: 0.758 ± 0.367
0.0TrpGly: 0.0 ± 0.0
0.379TrpHis: 0.379 ± 0.348
0.0TrpIle: 0.0 ± 0.0
2.274TrpLys: 2.274 ± 1.046
0.758TrpLeu: 0.758 ± 0.503
0.379TrpMet: 0.379 ± 0.446
0.758TrpAsn: 0.758 ± 0.367
0.379TrpPro: 0.379 ± 0.495
0.758TrpGln: 0.758 ± 0.367
0.379TrpArg: 0.379 ± 0.275
1.516TrpSer: 1.516 ± 0.677
0.758TrpThr: 0.758 ± 0.534
0.379TrpVal: 0.379 ± 0.33
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.274TyrAla: 2.274 ± 0.904
0.379TyrCys: 0.379 ± 0.443
0.379TyrAsp: 0.379 ± 0.33
0.758TyrGlu: 0.758 ± 0.439
2.274TyrPhe: 2.274 ± 0.731
1.516TyrGly: 1.516 ± 0.633
0.758TyrHis: 0.758 ± 0.686
3.412TyrIle: 3.412 ± 1.014
3.033TyrLys: 3.033 ± 0.583
3.412TyrLeu: 3.412 ± 1.078
0.379TyrMet: 0.379 ± 0.303
2.274TyrAsn: 2.274 ± 0.674
2.274TyrPro: 2.274 ± 1.015
4.17TyrGln: 4.17 ± 1.442
1.516TyrArg: 1.516 ± 0.676
0.379TyrSer: 0.379 ± 0.436
0.758TyrThr: 0.758 ± 0.439
3.033TyrVal: 3.033 ± 0.688
0.0TyrTrp: 0.0 ± 0.0
1.516TyrTyr: 1.516 ± 0.951
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 9 proteins (2639 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski