Amino acid dipepetide frequency for Blueberry shock virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.089AlaAla: 5.089 ± 1.816
1.272AlaCys: 1.272 ± 0.595
2.12AlaAsp: 2.12 ± 1.115
5.089AlaGlu: 5.089 ± 3.263
3.817AlaPhe: 3.817 ± 0.54
4.665AlaGly: 4.665 ± 2.267
1.272AlaHis: 1.272 ± 0.461
4.665AlaIle: 4.665 ± 1.835
3.393AlaLys: 3.393 ± 1.081
6.785AlaLeu: 6.785 ± 1.908
1.272AlaMet: 1.272 ± 0.461
3.393AlaAsn: 3.393 ± 0.984
2.545AlaPro: 2.545 ± 2.432
1.696AlaGln: 1.696 ± 0.54
1.696AlaArg: 1.696 ± 0.748
5.089AlaSer: 5.089 ± 0.994
3.393AlaThr: 3.393 ± 1.206
2.969AlaVal: 2.969 ± 1.19
0.848AlaTrp: 0.848 ± 0.544
0.848AlaTyr: 0.848 ± 0.305
0.0AlaXaa: 0.0 ± 0.0
Cys
0.848CysAla: 0.848 ± 0.305
0.424CysCys: 0.424 ± 0.272
0.848CysAsp: 0.848 ± 0.305
1.696CysGlu: 1.696 ± 0.492
0.848CysPhe: 0.848 ± 0.544
1.696CysGly: 1.696 ± 0.74
1.272CysHis: 1.272 ± 0.678
0.424CysIle: 0.424 ± 0.348
0.848CysLys: 0.848 ± 1.497
2.969CysLeu: 2.969 ± 1.174
0.0CysMet: 0.0 ± 0.0
1.272CysAsn: 1.272 ± 0.678
1.272CysPro: 1.272 ± 0.461
0.424CysGln: 0.424 ± 0.272
0.424CysArg: 0.424 ± 0.749
2.12CysSer: 2.12 ± 0.717
0.424CysThr: 0.424 ± 0.348
1.272CysVal: 1.272 ± 0.816
0.0CysTrp: 0.0 ± 0.0
0.424CysTyr: 0.424 ± 0.348
0.0CysXaa: 0.0 ± 0.0
Asp
2.969AspAla: 2.969 ± 0.681
0.424AspCys: 0.424 ± 0.348
5.513AspAsp: 5.513 ± 1.486
5.937AspGlu: 5.937 ± 1.286
2.545AspPhe: 2.545 ± 0.922
3.817AspGly: 3.817 ± 1.32
0.424AspHis: 0.424 ± 0.272
3.393AspIle: 3.393 ± 1.483
5.937AspLys: 5.937 ± 0.761
8.906AspLeu: 8.906 ± 2.712
1.272AspMet: 1.272 ± 0.595
0.848AspAsn: 0.848 ± 0.586
3.393AspPro: 3.393 ± 1.47
0.424AspGln: 0.424 ± 0.749
4.665AspArg: 4.665 ± 0.519
4.665AspSer: 4.665 ± 1.059
3.393AspThr: 3.393 ± 1.201
5.089AspVal: 5.089 ± 1.133
2.12AspTrp: 2.12 ± 0.984
2.545AspTyr: 2.545 ± 0.578
0.0AspXaa: 0.0 ± 0.0
Glu
7.209GluAla: 7.209 ± 2.488
1.272GluCys: 1.272 ± 0.816
3.817GluAsp: 3.817 ± 2.205
4.665GluGlu: 4.665 ± 0.572
2.545GluPhe: 2.545 ± 1.277
2.969GluGly: 2.969 ± 1.023
1.272GluHis: 1.272 ± 0.741
5.089GluIle: 5.089 ± 0.467
3.393GluLys: 3.393 ± 0.91
6.361GluLeu: 6.361 ± 1.398
0.848GluMet: 0.848 ± 1.335
1.696GluAsn: 1.696 ± 1.112
2.545GluPro: 2.545 ± 1.191
2.12GluGln: 2.12 ± 1.078
7.634GluArg: 7.634 ± 1.756
2.12GluSer: 2.12 ± 0.879
3.393GluThr: 3.393 ± 0.984
6.361GluVal: 6.361 ± 1.204
0.848GluTrp: 0.848 ± 0.305
1.696GluTyr: 1.696 ± 1.595
0.0GluXaa: 0.0 ± 0.0
Phe
2.969PheAla: 2.969 ± 0.669
1.272PheCys: 1.272 ± 0.609
3.393PheAsp: 3.393 ± 0.662
3.393PheGlu: 3.393 ± 2.432
2.545PhePhe: 2.545 ± 0.497
2.12PheGly: 2.12 ± 0.734
0.424PheHis: 0.424 ± 0.348
3.393PheIle: 3.393 ± 1.185
2.545PheLys: 2.545 ± 1.218
6.361PheLeu: 6.361 ± 2.104
0.0PheMet: 0.0 ± 0.0
2.545PheAsn: 2.545 ± 1.277
2.969PhePro: 2.969 ± 0.576
1.272PheGln: 1.272 ± 0.461
2.545PheArg: 2.545 ± 0.922
2.545PheSer: 2.545 ± 1.277
2.969PheThr: 2.969 ± 0.669
5.089PheVal: 5.089 ± 0.665
0.848PheTrp: 0.848 ± 0.65
0.848PheTyr: 0.848 ± 0.305
0.0PheXaa: 0.0 ± 0.0
Gly
2.545GlyAla: 2.545 ± 1.284
1.696GlyCys: 1.696 ± 0.54
4.665GlyAsp: 4.665 ± 1.945
2.969GlyGlu: 2.969 ± 1.208
2.545GlyPhe: 2.545 ± 2.073
2.969GlyGly: 2.969 ± 0.999
0.424GlyHis: 0.424 ± 0.272
1.272GlyIle: 1.272 ± 1.045
5.513GlyLys: 5.513 ± 1.426
3.817GlyLeu: 3.817 ± 0.54
1.272GlyMet: 1.272 ± 0.374
2.545GlyAsn: 2.545 ± 0.487
3.393GlyPro: 3.393 ± 1.819
0.424GlyGln: 0.424 ± 0.749
2.12GlyArg: 2.12 ± 1.367
2.12GlySer: 2.12 ± 0.606
3.817GlyThr: 3.817 ± 1.094
5.089GlyVal: 5.089 ± 0.806
0.848GlyTrp: 0.848 ± 1.497
2.545GlyTyr: 2.545 ± 0.922
0.0GlyXaa: 0.0 ± 0.0
His
1.696HisAla: 1.696 ± 0.794
0.848HisCys: 0.848 ± 0.544
0.848HisAsp: 0.848 ± 0.305
2.545HisGlu: 2.545 ± 0.598
0.0HisPhe: 0.0 ± 0.0
1.272HisGly: 1.272 ± 0.678
0.848HisHis: 0.848 ± 0.305
1.272HisIle: 1.272 ± 0.937
1.272HisLys: 1.272 ± 0.816
2.969HisLeu: 2.969 ± 0.912
0.848HisMet: 0.848 ± 0.586
0.848HisAsn: 0.848 ± 0.305
0.424HisPro: 0.424 ± 0.749
0.848HisGln: 0.848 ± 0.586
1.272HisArg: 1.272 ± 0.461
1.272HisSer: 1.272 ± 0.816
2.12HisThr: 2.12 ± 0.601
2.12HisVal: 2.12 ± 0.946
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
4.665IleAla: 4.665 ± 0.882
0.424IleCys: 0.424 ± 0.667
3.817IleAsp: 3.817 ± 1.472
2.545IleGlu: 2.545 ± 0.598
1.696IlePhe: 1.696 ± 0.926
2.969IleGly: 2.969 ± 2.133
0.424IleHis: 0.424 ± 0.272
1.696IleIle: 1.696 ± 0.693
3.393IleLys: 3.393 ± 1.015
2.545IleLeu: 2.545 ± 0.497
0.848IleMet: 0.848 ± 0.926
3.393IleAsn: 3.393 ± 0.843
4.241IlePro: 4.241 ± 0.384
1.696IleGln: 1.696 ± 0.508
2.12IleArg: 2.12 ± 1.367
4.665IleSer: 4.665 ± 1.62
3.393IleThr: 3.393 ± 0.984
2.12IleVal: 2.12 ± 0.643
0.848IleTrp: 0.848 ± 0.305
2.545IleTyr: 2.545 ± 1.4
0.0IleXaa: 0.0 ± 0.0
Lys
4.241LysAla: 4.241 ± 0.936
1.696LysCys: 1.696 ± 0.74
3.817LysAsp: 3.817 ± 1.094
4.241LysGlu: 4.241 ± 0.845
5.089LysPhe: 5.089 ± 2.221
2.969LysGly: 2.969 ± 2.008
1.272LysHis: 1.272 ± 0.461
2.969LysIle: 2.969 ± 0.999
4.241LysLys: 4.241 ± 0.743
5.937LysLeu: 5.937 ± 1.74
1.272LysMet: 1.272 ± 0.565
2.545LysAsn: 2.545 ± 1.4
3.393LysPro: 3.393 ± 1.398
1.696LysGln: 1.696 ± 0.88
3.817LysArg: 3.817 ± 0.578
6.361LysSer: 6.361 ± 0.691
5.937LysThr: 5.937 ± 1.828
5.937LysVal: 5.937 ± 1.458
0.848LysTrp: 0.848 ± 0.544
2.12LysTyr: 2.12 ± 1.267
0.0LysXaa: 0.0 ± 0.0
Leu
4.665LeuAla: 4.665 ± 1.237
0.848LeuCys: 0.848 ± 0.305
5.089LeuAsp: 5.089 ± 2.381
6.361LeuGlu: 6.361 ± 1.156
5.089LeuPhe: 5.089 ± 2.294
5.089LeuGly: 5.089 ± 0.955
2.969LeuHis: 2.969 ± 1.16
5.089LeuIle: 5.089 ± 1.173
6.361LeuLys: 6.361 ± 1.371
9.33LeuLeu: 9.33 ± 1.601
3.817LeuMet: 3.817 ± 1.088
3.393LeuAsn: 3.393 ± 1.919
4.241LeuPro: 4.241 ± 0.384
4.665LeuGln: 4.665 ± 1.489
5.513LeuArg: 5.513 ± 1.586
8.058LeuSer: 8.058 ± 1.487
5.513LeuThr: 5.513 ± 1.364
7.209LeuVal: 7.209 ± 0.393
0.0LeuTrp: 0.0 ± 0.0
1.696LeuTyr: 1.696 ± 0.88
0.0LeuXaa: 0.0 ± 0.0
Met
2.545MetAla: 2.545 ± 0.598
0.0MetCys: 0.0 ± 0.0
2.545MetAsp: 2.545 ± 0.497
2.12MetGlu: 2.12 ± 1.026
1.272MetPhe: 1.272 ± 0.696
1.272MetGly: 1.272 ± 0.816
0.424MetHis: 0.424 ± 0.272
1.272MetIle: 1.272 ± 0.461
0.848MetLys: 0.848 ± 1.335
2.545MetLeu: 2.545 ± 0.936
1.696MetMet: 1.696 ± 0.508
0.424MetAsn: 0.424 ± 0.348
0.848MetPro: 0.848 ± 0.586
0.424MetGln: 0.424 ± 0.272
0.424MetArg: 0.424 ± 0.348
1.272MetSer: 1.272 ± 0.468
0.848MetThr: 0.848 ± 1.034
0.848MetVal: 0.848 ± 1.034
0.424MetTrp: 0.424 ± 0.348
1.696MetTyr: 1.696 ± 0.61
0.0MetXaa: 0.0 ± 0.0
Asn
2.545AsnAla: 2.545 ± 0.497
0.0AsnCys: 0.0 ± 0.0
3.393AsnAsp: 3.393 ± 2.302
1.696AsnGlu: 1.696 ± 0.508
5.089AsnPhe: 5.089 ± 1.295
1.272AsnGly: 1.272 ± 1.386
1.272AsnHis: 1.272 ± 1.386
0.848AsnIle: 0.848 ± 0.305
5.089AsnLys: 5.089 ± 1.254
1.696AsnLeu: 1.696 ± 1.112
1.696AsnMet: 1.696 ± 1.112
1.696AsnAsn: 1.696 ± 0.88
2.545AsnPro: 2.545 ± 1.414
1.272AsnGln: 1.272 ± 0.609
2.545AsnArg: 2.545 ± 1.191
1.272AsnSer: 1.272 ± 0.468
2.969AsnThr: 2.969 ± 0.569
4.241AsnVal: 4.241 ± 0.778
0.424AsnTrp: 0.424 ± 0.272
1.696AsnTyr: 1.696 ± 0.61
0.0AsnXaa: 0.0 ± 0.0
Pro
2.545ProAla: 2.545 ± 1.17
1.696ProCys: 1.696 ± 0.926
2.969ProAsp: 2.969 ± 0.741
1.272ProGlu: 1.272 ± 0.741
1.272ProPhe: 1.272 ± 0.595
1.696ProGly: 1.696 ± 0.74
0.848ProHis: 0.848 ± 0.305
3.393ProIle: 3.393 ± 2.451
4.241ProLys: 4.241 ± 0.384
3.393ProLeu: 3.393 ± 0.802
0.424ProMet: 0.424 ± 0.348
5.089ProAsn: 5.089 ± 1.889
0.848ProPro: 0.848 ± 0.65
0.848ProGln: 0.848 ± 1.034
2.12ProArg: 2.12 ± 0.717
4.241ProSer: 4.241 ± 2.844
3.817ProThr: 3.817 ± 1.117
2.545ProVal: 2.545 ± 0.827
0.424ProTrp: 0.424 ± 0.348
0.424ProTyr: 0.424 ± 0.348
0.0ProXaa: 0.0 ± 0.0
Gln
2.545GlnAla: 2.545 ± 1.414
1.272GlnCys: 1.272 ± 0.678
0.848GlnAsp: 0.848 ± 1.034
1.696GlnGlu: 1.696 ± 0.74
1.272GlnPhe: 1.272 ± 0.595
1.272GlnGly: 1.272 ± 0.816
0.0GlnHis: 0.0 ± 0.0
1.272GlnIle: 1.272 ± 0.461
1.272GlnLys: 1.272 ± 0.921
2.12GlnLeu: 2.12 ± 0.62
0.848GlnMet: 0.848 ± 0.697
1.696GlnAsn: 1.696 ± 0.907
0.848GlnPro: 0.848 ± 1.034
2.545GlnGln: 2.545 ± 0.497
1.272GlnArg: 1.272 ± 0.696
1.272GlnSer: 1.272 ± 0.816
1.272GlnThr: 1.272 ± 0.468
1.696GlnVal: 1.696 ± 0.74
0.424GlnTrp: 0.424 ± 0.749
1.272GlnTyr: 1.272 ± 0.741
0.0GlnXaa: 0.0 ± 0.0
Arg
0.424ArgAla: 0.424 ± 0.749
1.272ArgCys: 1.272 ± 0.678
5.513ArgAsp: 5.513 ± 1.422
5.513ArgGlu: 5.513 ± 1.595
1.272ArgPhe: 1.272 ± 0.461
4.241ArgGly: 4.241 ± 1.474
1.696ArgHis: 1.696 ± 0.693
4.665ArgIle: 4.665 ± 2.122
3.817ArgLys: 3.817 ± 1.622
3.817ArgLeu: 3.817 ± 1.472
1.696ArgMet: 1.696 ± 0.492
2.12ArgAsn: 2.12 ± 0.733
2.545ArgPro: 2.545 ± 0.598
0.848ArgGln: 0.848 ± 0.544
1.696ArgArg: 1.696 ± 0.61
4.241ArgSer: 4.241 ± 0.6
4.665ArgThr: 4.665 ± 0.539
2.545ArgVal: 2.545 ± 0.598
1.696ArgTrp: 1.696 ± 0.492
0.848ArgTyr: 0.848 ± 0.305
0.0ArgXaa: 0.0 ± 0.0
Ser
4.665SerAla: 4.665 ± 2.132
2.12SerCys: 2.12 ± 0.922
7.634SerAsp: 7.634 ± 0.246
3.817SerGlu: 3.817 ± 0.833
4.241SerPhe: 4.241 ± 0.281
2.969SerGly: 2.969 ± 0.576
2.12SerHis: 2.12 ± 0.879
2.969SerIle: 2.969 ± 0.669
4.665SerLys: 4.665 ± 1.748
6.785SerLeu: 6.785 ± 0.6
1.696SerMet: 1.696 ± 1.173
3.393SerAsn: 3.393 ± 1.353
3.393SerPro: 3.393 ± 2.246
0.848SerGln: 0.848 ± 0.586
5.513SerArg: 5.513 ± 1.507
7.209SerSer: 7.209 ± 0.863
3.817SerThr: 3.817 ± 2.299
5.089SerVal: 5.089 ± 0.467
0.424SerTrp: 0.424 ± 0.348
0.848SerTyr: 0.848 ± 0.305
0.0SerXaa: 0.0 ± 0.0
Thr
2.969ThrAla: 2.969 ± 0.971
0.848ThrCys: 0.848 ± 0.305
2.545ThrAsp: 2.545 ± 1.17
4.241ThrGlu: 4.241 ± 1.054
2.545ThrPhe: 2.545 ± 0.914
3.817ThrGly: 3.817 ± 1.117
2.12ThrHis: 2.12 ± 0.922
2.545ThrIle: 2.545 ± 0.914
5.513ThrLys: 5.513 ± 1.661
6.361ThrLeu: 6.361 ± 0.392
0.848ThrMet: 0.848 ± 0.305
2.545ThrAsn: 2.545 ± 0.914
0.848ThrPro: 0.848 ± 0.544
1.272ThrGln: 1.272 ± 0.461
2.969ThrArg: 2.969 ± 1.452
5.937ThrSer: 5.937 ± 2.773
5.089ThrThr: 5.089 ± 1.753
4.241ThrVal: 4.241 ± 0.936
0.0ThrTrp: 0.0 ± 0.0
3.393ThrTyr: 3.393 ± 0.662
0.0ThrXaa: 0.0 ± 0.0
Val
4.665ValAla: 4.665 ± 1.97
1.272ValCys: 1.272 ± 0.937
5.513ValAsp: 5.513 ± 2.182
3.817ValGlu: 3.817 ± 0.894
4.665ValPhe: 4.665 ± 1.237
4.241ValGly: 4.241 ± 1.831
2.545ValHis: 2.545 ± 0.856
2.969ValIle: 2.969 ± 0.999
5.937ValLys: 5.937 ± 0.737
7.209ValLeu: 7.209 ± 1.431
2.12ValMet: 2.12 ± 0.606
2.969ValAsn: 2.969 ± 0.669
3.393ValPro: 3.393 ± 1.398
2.12ValGln: 2.12 ± 2.037
5.513ValArg: 5.513 ± 2.334
5.513ValSer: 5.513 ± 1.161
1.696ValThr: 1.696 ± 0.54
3.817ValVal: 3.817 ± 1.094
0.0ValTrp: 0.0 ± 0.0
2.12ValTyr: 2.12 ± 1.115
0.0ValXaa: 0.0 ± 0.0
Trp
0.848TrpAla: 0.848 ± 0.697
0.0TrpCys: 0.0 ± 0.0
1.272TrpAsp: 1.272 ± 0.741
1.272TrpGlu: 1.272 ± 0.595
0.424TrpPhe: 0.424 ± 0.348
0.848TrpGly: 0.848 ± 0.65
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
1.272TrpLeu: 1.272 ± 0.609
0.424TrpMet: 0.424 ± 0.272
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.424TrpGln: 0.424 ± 0.749
0.0TrpArg: 0.0 ± 0.0
1.272TrpSer: 1.272 ± 0.461
0.848TrpThr: 0.848 ± 0.66
0.848TrpVal: 0.848 ± 0.66
0.424TrpTrp: 0.424 ± 0.272
1.272TrpTyr: 1.272 ± 0.595
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.272TyrAla: 1.272 ± 0.816
0.848TyrCys: 0.848 ± 0.305
2.12TyrAsp: 2.12 ± 0.601
2.969TyrGlu: 2.969 ± 0.669
1.272TyrPhe: 1.272 ± 0.468
0.424TyrGly: 0.424 ± 0.272
1.696TyrHis: 1.696 ± 0.926
0.848TyrIle: 0.848 ± 0.697
2.545TyrLys: 2.545 ± 0.497
3.817TyrLeu: 3.817 ± 0.809
0.424TyrMet: 0.424 ± 0.348
0.848TyrAsn: 0.848 ± 0.305
0.424TyrPro: 0.424 ± 0.749
0.848TyrGln: 0.848 ± 0.697
1.272TyrArg: 1.272 ± 0.468
2.969TyrSer: 2.969 ± 1.116
1.272TyrThr: 1.272 ± 0.816
2.969TyrVal: 2.969 ± 0.327
0.0TyrTrp: 0.0 ± 0.0
0.848TyrTyr: 0.848 ± 0.305
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (2359 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski