Amino acid dipepetide frequency for Mucilaginibacter pineti

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.917AlaAla: 6.917 ± 0.071	0.689AlaCys: 0.689 ± 0.018	4.973AlaAsp: 4.973 ± 0.058	4.233AlaGlu: 4.233 ± 0.048	3.615AlaPhe: 3.615 ± 0.045	5.999AlaGly: 5.999 ± 0.068	1.329AlaHis: 1.329 ± 0.027	5.709AlaIle: 5.709 ± 0.054	4.741AlaLys: 4.741 ± 0.051	7.141AlaLeu: 7.141 ± 0.07	1.735AlaMet: 1.735 ± 0.028	3.91AlaAsn: 3.91 ± 0.054	2.453AlaPro: 2.453 ± 0.041	3.104AlaGln: 3.104 ± 0.041	2.594AlaArg: 2.594 ± 0.043	4.519AlaSer: 4.519 ± 0.054	4.355AlaThr: 4.355 ± 0.059	5.032AlaVal: 5.032 ± 0.055	0.845AlaTrp: 0.845 ± 0.022	3.121AlaTyr: 3.121 ± 0.038	0.0AlaXaa: 0.0 ± 0.0
Cys	0.528CysAla: 0.528 ± 0.017	0.152CysCys: 0.152 ± 0.009	0.378CysAsp: 0.378 ± 0.011	0.334CysGlu: 0.334 ± 0.011	0.44CysPhe: 0.44 ± 0.014	0.629CysGly: 0.629 ± 0.022	0.197CysHis: 0.197 ± 0.011	0.597CysIle: 0.597 ± 0.018	0.518CysLys: 0.518 ± 0.017	0.841CysLeu: 0.841 ± 0.021	0.185CysMet: 0.185 ± 0.01	0.4CysAsn: 0.4 ± 0.014	0.307CysPro: 0.307 ± 0.011	0.227CysGln: 0.227 ± 0.01	0.352CysArg: 0.352 ± 0.013	0.516CysSer: 0.516 ± 0.017	0.426CysThr: 0.426 ± 0.014	0.456CysVal: 0.456 ± 0.015	0.092CysTrp: 0.092 ± 0.007	0.356CysTyr: 0.356 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	4.214AspAla: 4.214 ± 0.049	0.383AspCys: 0.383 ± 0.013	2.852AspAsp: 2.852 ± 0.045	3.368AspGlu: 3.368 ± 0.049	2.985AspPhe: 2.985 ± 0.042	3.9AspGly: 3.9 ± 0.051	1.138AspHis: 1.138 ± 0.025	3.994AspIle: 3.994 ± 0.047	3.906AspLys: 3.906 ± 0.05	4.99AspLeu: 4.99 ± 0.052	1.234AspMet: 1.234 ± 0.024	2.943AspAsn: 2.943 ± 0.034	2.224AspPro: 2.224 ± 0.035	1.905AspGln: 1.905 ± 0.034	2.101AspArg: 2.101 ± 0.033	2.97AspSer: 2.97 ± 0.047	2.844AspThr: 2.844 ± 0.038	3.498AspVal: 3.498 ± 0.043	0.802AspTrp: 0.802 ± 0.019	2.537AspTyr: 2.537 ± 0.037	0.0AspXaa: 0.0 ± 0.0
Glu	3.989GluAla: 3.989 ± 0.052	0.303GluCys: 0.303 ± 0.012	2.51GluAsp: 2.51 ± 0.038	2.971GluGlu: 2.971 ± 0.047	2.234GluPhe: 2.234 ± 0.035	2.977GluGly: 2.977 ± 0.035	1.081GluHis: 1.081 ± 0.024	3.993GluIle: 3.993 ± 0.05	4.201GluLys: 4.201 ± 0.053	5.606GluLeu: 5.606 ± 0.063	1.34GluMet: 1.34 ± 0.027	2.929GluAsn: 2.929 ± 0.039	1.648GluPro: 1.648 ± 0.027	2.401GluGln: 2.401 ± 0.038	2.402GluArg: 2.402 ± 0.038	2.566GluSer: 2.566 ± 0.033	2.812GluThr: 2.812 ± 0.04	3.385GluVal: 3.385 ± 0.038	0.615GluTrp: 0.615 ± 0.016	1.911GluTyr: 1.911 ± 0.032	0.0GluXaa: 0.0 ± 0.0
Phe	3.469PheAla: 3.469 ± 0.043	0.481PheCys: 0.481 ± 0.014	2.915PheAsp: 2.915 ± 0.031	2.568PheGlu: 2.568 ± 0.04	2.452PhePhe: 2.452 ± 0.039	3.402PheGly: 3.402 ± 0.051	0.87PheHis: 0.87 ± 0.022	3.616PheIle: 3.616 ± 0.049	3.379PheLys: 3.379 ± 0.039	4.18PheLeu: 4.18 ± 0.053	1.103PheMet: 1.103 ± 0.024	3.154PheAsn: 3.154 ± 0.043	1.695PhePro: 1.695 ± 0.027	1.352PheGln: 1.352 ± 0.027	1.817PheArg: 1.817 ± 0.03	3.519PheSer: 3.519 ± 0.047	3.297PheThr: 3.297 ± 0.044	2.763PheVal: 2.763 ± 0.039	0.595PheTrp: 0.595 ± 0.018	2.185PheTyr: 2.185 ± 0.033	0.0PheXaa: 0.0 ± 0.0
Gly	4.587GlyAla: 4.587 ± 0.057	0.593GlyCys: 0.593 ± 0.019	3.585GlyAsp: 3.585 ± 0.044	3.145GlyGlu: 3.145 ± 0.044	3.719GlyPhe: 3.719 ± 0.047	4.915GlyGly: 4.915 ± 0.07	1.303GlyHis: 1.303 ± 0.027	5.275GlyIle: 5.275 ± 0.061	5.234GlyLys: 5.234 ± 0.051	6.396GlyLeu: 6.396 ± 0.067	1.595GlyMet: 1.595 ± 0.029	3.861GlyAsn: 3.861 ± 0.055	1.726GlyPro: 1.726 ± 0.03	2.341GlyGln: 2.341 ± 0.038	2.584GlyArg: 2.584 ± 0.041	4.412GlySer: 4.412 ± 0.057	4.25GlyThr: 4.25 ± 0.059	4.298GlyVal: 4.298 ± 0.052	0.966GlyTrp: 0.966 ± 0.024	3.229GlyTyr: 3.229 ± 0.049	0.0GlyXaa: 0.0 ± 0.0
His	1.182HisAla: 1.182 ± 0.026	0.195HisCys: 0.195 ± 0.01	1.008HisAsp: 1.008 ± 0.023	1.005HisGlu: 1.005 ± 0.02	1.151HisPhe: 1.151 ± 0.024	1.141HisGly: 1.141 ± 0.025	0.559HisHis: 0.559 ± 0.02	1.518HisIle: 1.518 ± 0.03	1.1HisLys: 1.1 ± 0.024	1.934HisLeu: 1.934 ± 0.034	0.401HisMet: 0.401 ± 0.013	0.995HisAsn: 0.995 ± 0.021	1.026HisPro: 1.026 ± 0.022	0.79HisGln: 0.79 ± 0.019	0.775HisArg: 0.775 ± 0.021	1.108HisSer: 1.108 ± 0.025	1.103HisThr: 1.103 ± 0.026	0.976HisVal: 0.976 ± 0.024	0.253HisTrp: 0.253 ± 0.01	0.914HisTyr: 0.914 ± 0.021	0.0HisXaa: 0.0 ± 0.0
Ile	6.094IleAla: 6.094 ± 0.062	0.718IleCys: 0.718 ± 0.019	4.245IleAsp: 4.245 ± 0.046	3.78IleGlu: 3.78 ± 0.049	3.025IlePhe: 3.025 ± 0.049	4.798IleGly: 4.798 ± 0.057	1.278IleHis: 1.278 ± 0.031	5.219IleIle: 5.219 ± 0.064	5.211IleLys: 5.211 ± 0.059	6.144IleLeu: 6.144 ± 0.07	1.371IleMet: 1.371 ± 0.025	4.565IleAsn: 4.565 ± 0.056	3.058IlePro: 3.058 ± 0.04	2.243IleGln: 2.243 ± 0.029	2.896IleArg: 2.896 ± 0.04	5.082IleSer: 5.082 ± 0.056	4.938IleThr: 4.938 ± 0.058	4.182IleVal: 4.182 ± 0.042	0.774IleTrp: 0.774 ± 0.018	2.728IleTyr: 2.728 ± 0.041	0.0IleXaa: 0.0 ± 0.0
Lys	5.431LysAla: 5.431 ± 0.059	0.332LysCys: 0.332 ± 0.013	4.009LysAsp: 4.009 ± 0.049	3.985LysGlu: 3.985 ± 0.058	2.662LysPhe: 2.662 ± 0.036	4.452LysGly: 4.452 ± 0.049	1.32LysHis: 1.32 ± 0.025	4.828LysIle: 4.828 ± 0.062	5.322LysLys: 5.322 ± 0.064	6.484LysLeu: 6.484 ± 0.062	1.79LysMet: 1.79 ± 0.033	4.128LysAsn: 4.128 ± 0.05	2.965LysPro: 2.965 ± 0.042	3.01LysGln: 3.01 ± 0.041	2.729LysArg: 2.729 ± 0.043	3.852LysSer: 3.852 ± 0.042	4.384LysThr: 4.384 ± 0.045	4.425LysVal: 4.425 ± 0.051	0.785LysTrp: 0.785 ± 0.018	2.934LysTyr: 2.934 ± 0.043	0.0LysXaa: 0.0 ± 0.0
Leu	7.202LeuAla: 7.202 ± 0.066	0.835LeuCys: 0.835 ± 0.021	4.633LeuAsp: 4.633 ± 0.051	4.368LeuGlu: 4.368 ± 0.06	4.773LeuPhe: 4.773 ± 0.055	5.662LeuGly: 5.662 ± 0.055	1.799LeuHis: 1.799 ± 0.031	6.794LeuIle: 6.794 ± 0.074	7.4LeuLys: 7.4 ± 0.073	9.823LeuLeu: 9.823 ± 0.096	2.155LeuMet: 2.155 ± 0.034	5.838LeuAsn: 5.838 ± 0.064	4.194LeuPro: 4.194 ± 0.046	3.855LeuGln: 3.855 ± 0.044	3.711LeuArg: 3.711 ± 0.047	6.871LeuSer: 6.871 ± 0.058	5.906LeuThr: 5.906 ± 0.055	5.431LeuVal: 5.431 ± 0.055	0.997LeuTrp: 0.997 ± 0.022	3.456LeuTyr: 3.456 ± 0.045	0.0LeuXaa: 0.0 ± 0.0
Met	1.894MetAla: 1.894 ± 0.03	0.143MetCys: 0.143 ± 0.008	1.202MetAsp: 1.202 ± 0.026	1.3MetGlu: 1.3 ± 0.025	0.823MetPhe: 0.823 ± 0.022	1.421MetGly: 1.421 ± 0.027	0.449MetHis: 0.449 ± 0.016	1.454MetIle: 1.454 ± 0.028	1.895MetLys: 1.895 ± 0.029	2.186MetLeu: 2.186 ± 0.036	0.555MetMet: 0.555 ± 0.02	1.201MetAsn: 1.201 ± 0.024	1.085MetPro: 1.085 ± 0.024	1.004MetGln: 1.004 ± 0.019	0.954MetArg: 0.954 ± 0.022	1.238MetSer: 1.238 ± 0.023	1.075MetThr: 1.075 ± 0.019	1.478MetVal: 1.478 ± 0.028	0.174MetTrp: 0.174 ± 0.009	0.653MetTyr: 0.653 ± 0.015	0.0MetXaa: 0.0 ± 0.0
Asn	4.127AsnAla: 4.127 ± 0.047	0.403AsnCys: 0.403 ± 0.014	2.964AsnAsp: 2.964 ± 0.038	2.866AsnGlu: 2.866 ± 0.038	2.675AsnPhe: 2.675 ± 0.043	4.251AsnGly: 4.251 ± 0.054	1.057AsnHis: 1.057 ± 0.022	4.198AsnIle: 4.198 ± 0.051	3.794AsnLys: 3.794 ± 0.044	5.101AsnLeu: 5.101 ± 0.059	1.208AsnMet: 1.208 ± 0.023	3.495AsnAsn: 3.495 ± 0.054	2.712AsnPro: 2.712 ± 0.037	2.134AsnGln: 2.134 ± 0.033	2.241AsnArg: 2.241 ± 0.039	3.445AsnSer: 3.445 ± 0.047	3.456AsnThr: 3.456 ± 0.048	3.226AsnVal: 3.226 ± 0.048	0.783AsnTrp: 0.783 ± 0.018	2.812AsnTyr: 2.812 ± 0.046	0.0AsnXaa: 0.0 ± 0.0
Pro	3.577ProAla: 3.577 ± 0.045	0.216ProCys: 0.216 ± 0.01	2.697ProAsp: 2.697 ± 0.038	2.661ProGlu: 2.661 ± 0.041	1.943ProPhe: 1.943 ± 0.033	3.056ProGly: 3.056 ± 0.04	0.72ProHis: 0.72 ± 0.019	2.313ProIle: 2.313 ± 0.029	2.184ProLys: 2.184 ± 0.036	3.486ProLeu: 3.486 ± 0.04	0.739ProMet: 0.739 ± 0.02	1.989ProAsn: 1.989 ± 0.028	1.161ProPro: 1.161 ± 0.027	1.605ProGln: 1.605 ± 0.026	1.088ProArg: 1.088 ± 0.024	2.12ProSer: 2.12 ± 0.034	1.998ProThr: 1.998 ± 0.037	3.435ProVal: 3.435 ± 0.047	0.457ProTrp: 0.457 ± 0.014	1.644ProTyr: 1.644 ± 0.031	0.0ProXaa: 0.0 ± 0.0
Gln	2.852GlnAla: 2.852 ± 0.038	0.197GlnCys: 0.197 ± 0.01	1.702GlnAsp: 1.702 ± 0.031	1.95GlnGlu: 1.95 ± 0.031	1.685GlnPhe: 1.685 ± 0.029	2.07GlnGly: 2.07 ± 0.034	0.841GlnHis: 0.841 ± 0.02	2.551GlnIle: 2.551 ± 0.035	2.756GlnLys: 2.756 ± 0.041	4.193GlnLeu: 4.193 ± 0.044	0.921GlnMet: 0.921 ± 0.021	2.133GlnAsn: 2.133 ± 0.034	1.621GlnPro: 1.621 ± 0.028	2.392GlnGln: 2.392 ± 0.052	1.524GlnArg: 1.524 ± 0.03	2.316GlnSer: 2.316 ± 0.034	2.301GlnThr: 2.301 ± 0.029	2.56GlnVal: 2.56 ± 0.03	0.471GlnTrp: 0.471 ± 0.016	1.593GlnTyr: 1.593 ± 0.027	0.0GlnXaa: 0.0 ± 0.0
Arg	2.458ArgAla: 2.458 ± 0.039	0.232ArgCys: 0.232 ± 0.01	2.052ArgAsp: 2.052 ± 0.034	2.156ArgGlu: 2.156 ± 0.034	2.122ArgPhe: 2.122 ± 0.031	2.135ArgGly: 2.135 ± 0.034	0.733ArgHis: 0.733 ± 0.02	2.952ArgIle: 2.952 ± 0.04	2.807ArgLys: 2.807 ± 0.038	3.968ArgLeu: 3.968 ± 0.044	1.023ArgMet: 1.023 ± 0.02	2.121ArgAsn: 2.121 ± 0.034	1.42ArgPro: 1.42 ± 0.032	1.582ArgGln: 1.582 ± 0.028	1.609ArgArg: 1.609 ± 0.03	2.328ArgSer: 2.328 ± 0.031	2.021ArgThr: 2.021 ± 0.03	2.357ArgVal: 2.357 ± 0.033	0.557ArgTrp: 0.557 ± 0.016	1.875ArgTyr: 1.875 ± 0.034	0.0ArgXaa: 0.0 ± 0.0
Ser	4.949SerAla: 4.949 ± 0.049	0.563SerCys: 0.563 ± 0.017	3.055SerAsp: 3.055 ± 0.04	2.749SerGlu: 2.749 ± 0.037	3.532SerPhe: 3.532 ± 0.044	4.878SerGly: 4.878 ± 0.053	1.128SerHis: 1.128 ± 0.02	4.523SerIle: 4.523 ± 0.05	3.912SerLys: 3.912 ± 0.042	6.098SerLeu: 6.098 ± 0.061	1.213SerMet: 1.213 ± 0.026	3.193SerAsn: 3.193 ± 0.043	2.455SerPro: 2.455 ± 0.039	2.037SerGln: 2.037 ± 0.033	2.497SerArg: 2.497 ± 0.036	3.905SerSer: 3.905 ± 0.047	3.525SerThr: 3.525 ± 0.046	4.184SerVal: 4.184 ± 0.045	0.757SerTrp: 0.757 ± 0.019	2.804SerTyr: 2.804 ± 0.041	0.0SerXaa: 0.0 ± 0.0
Thr	5.08ThrAla: 5.08 ± 0.059	0.404ThrCys: 0.404 ± 0.015	3.65ThrAsp: 3.65 ± 0.046	2.909ThrGlu: 2.909 ± 0.045	2.833ThrPhe: 2.833 ± 0.04	5.106ThrGly: 5.106 ± 0.06	1.029ThrHis: 1.029 ± 0.024	4.511ThrIle: 4.511 ± 0.049	3.251ThrLys: 3.251 ± 0.044	5.582ThrLeu: 5.582 ± 0.061	0.994ThrMet: 0.994 ± 0.021	3.058ThrAsn: 3.058 ± 0.047	2.709ThrPro: 2.709 ± 0.041	2.102ThrGln: 2.102 ± 0.033	2.028ThrArg: 2.028 ± 0.033	3.532ThrSer: 3.532 ± 0.047	3.765ThrThr: 3.765 ± 0.06	4.106ThrVal: 4.106 ± 0.052	0.682ThrTrp: 0.682 ± 0.021	2.549ThrTyr: 2.549 ± 0.042	0.0ThrXaa: 0.0 ± 0.0
Val	4.732ValAla: 4.732 ± 0.052	0.586ValCys: 0.586 ± 0.015	3.349ValAsp: 3.349 ± 0.034	2.986ValGlu: 2.986 ± 0.039	3.192ValPhe: 3.192 ± 0.039	3.577ValGly: 3.577 ± 0.049	1.062ValHis: 1.062 ± 0.022	4.884ValIle: 4.884 ± 0.051	4.631ValLys: 4.631 ± 0.046	6.103ValLeu: 6.103 ± 0.057	1.456ValMet: 1.456 ± 0.029	3.754ValAsn: 3.754 ± 0.047	2.451ValPro: 2.451 ± 0.038	2.073ValGln: 2.073 ± 0.028	2.283ValArg: 2.283 ± 0.036	4.305ValSer: 4.305 ± 0.048	4.09ValThr: 4.09 ± 0.065	4.116ValVal: 4.116 ± 0.053	0.691ValTrp: 0.691 ± 0.017	2.552ValTyr: 2.552 ± 0.034	0.0ValXaa: 0.0 ± 0.0
Trp	0.798TrpAla: 0.798 ± 0.018	0.122TrpCys: 0.122 ± 0.006	0.648TrpAsp: 0.648 ± 0.019	0.624TrpGlu: 0.624 ± 0.016	0.62TrpPhe: 0.62 ± 0.019	0.825TrpGly: 0.825 ± 0.024	0.29TrpHis: 0.29 ± 0.011	0.795TrpIle: 0.795 ± 0.022	0.79TrpLys: 0.79 ± 0.021	1.28TrpLeu: 1.28 ± 0.023	0.342TrpMet: 0.342 ± 0.013	0.675TrpAsn: 0.675 ± 0.02	0.401TrpPro: 0.401 ± 0.013	0.63TrpGln: 0.63 ± 0.02	0.487TrpArg: 0.487 ± 0.016	0.668TrpSer: 0.668 ± 0.02	0.64TrpThr: 0.64 ± 0.018	0.711TrpVal: 0.711 ± 0.02	0.21TrpTrp: 0.21 ± 0.009	0.508TrpTyr: 0.508 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.934TyrAla: 2.934 ± 0.04	0.382TyrCys: 0.382 ± 0.014	2.358TyrAsp: 2.358 ± 0.039	1.918TyrGlu: 1.918 ± 0.03	2.333TyrPhe: 2.333 ± 0.04	2.823TyrGly: 2.823 ± 0.042	0.949TyrHis: 0.949 ± 0.021	2.625TyrIle: 2.625 ± 0.039	2.795TyrLys: 2.795 ± 0.038	4.168TyrLeu: 4.168 ± 0.052	0.825TyrMet: 0.825 ± 0.021	2.607TyrAsn: 2.607 ± 0.041	1.776TyrPro: 1.776 ± 0.026	1.848TyrGln: 1.848 ± 0.026	1.833TyrArg: 1.833 ± 0.03	2.684TyrSer: 2.684 ± 0.038	2.695TyrThr: 2.695 ± 0.038	2.256TyrVal: 2.256 ± 0.032	0.555TyrTrp: 0.555 ± 0.016	2.054TyrTyr: 2.054 ± 0.04	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 6283 proteins (2125137 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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