Amino acid dipepetide frequency for Tortoise microvirus 100

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.076AlaAla: 2.076 ± 1.305
0.692AlaCys: 0.692 ± 0.649
2.768AlaAsp: 2.768 ± 1.448
4.152AlaGlu: 4.152 ± 2.264
1.384AlaPhe: 1.384 ± 0.656
2.076AlaGly: 2.076 ± 1.305
0.0AlaHis: 0.0 ± 0.0
1.384AlaIle: 1.384 ± 0.656
3.46AlaLys: 3.46 ± 1.344
3.46AlaLeu: 3.46 ± 1.444
2.076AlaMet: 2.076 ± 1.367
3.46AlaAsn: 3.46 ± 1.125
2.768AlaPro: 2.768 ± 1.148
2.076AlaGln: 2.076 ± 1.305
2.768AlaArg: 2.768 ± 1.224
5.536AlaSer: 5.536 ± 2.575
2.768AlaThr: 2.768 ± 1.148
2.076AlaVal: 2.076 ± 1.252
0.692AlaTrp: 0.692 ± 0.649
2.076AlaTyr: 2.076 ± 0.934
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.692CysGlu: 0.692 ± 0.649
0.692CysPhe: 0.692 ± 0.649
1.384CysGly: 1.384 ± 1.297
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.692CysLys: 0.692 ± 0.915
0.692CysLeu: 0.692 ± 0.417
0.692CysMet: 0.692 ± 0.417
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
1.384CysArg: 1.384 ± 1.019
0.692CysSer: 0.692 ± 0.649
0.692CysThr: 0.692 ± 0.649
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.692CysTyr: 0.692 ± 0.649
0.0CysXaa: 0.0 ± 0.0
Asp
1.384AspAla: 1.384 ± 0.656
0.692AspCys: 0.692 ± 0.417
3.46AspAsp: 3.46 ± 3.369
5.536AspGlu: 5.536 ± 3.046
2.076AspPhe: 2.076 ± 0.81
4.152AspGly: 4.152 ± 2.429
0.692AspHis: 0.692 ± 0.915
1.384AspIle: 1.384 ± 0.834
2.076AspLys: 2.076 ± 1.029
4.844AspLeu: 4.844 ± 1.659
0.692AspMet: 0.692 ± 0.417
2.768AspAsn: 2.768 ± 1.224
4.152AspPro: 4.152 ± 1.969
1.384AspGln: 1.384 ± 0.656
2.768AspArg: 2.768 ± 0.857
0.692AspSer: 0.692 ± 0.915
6.228AspThr: 6.228 ± 1.276
2.076AspVal: 2.076 ± 1.18
0.692AspTrp: 0.692 ± 0.713
6.92AspTyr: 6.92 ± 1.018
0.0AspXaa: 0.0 ± 0.0
Glu
2.076GluAla: 2.076 ± 1.056
0.0GluCys: 0.0 ± 0.0
2.076GluAsp: 2.076 ± 0.808
2.076GluGlu: 2.076 ± 0.836
4.844GluPhe: 4.844 ± 0.833
2.768GluGly: 2.768 ± 1.644
2.076GluHis: 2.076 ± 1.18
2.076GluIle: 2.076 ± 0.976
3.46GluLys: 3.46 ± 1.94
2.076GluLeu: 2.076 ± 0.836
1.384GluMet: 1.384 ± 0.865
3.46GluAsn: 3.46 ± 0.594
1.384GluPro: 1.384 ± 0.822
2.768GluGln: 2.768 ± 0.826
2.768GluArg: 2.768 ± 0.602
2.768GluSer: 2.768 ± 0.749
2.768GluThr: 2.768 ± 2.739
6.92GluVal: 6.92 ± 1.997
0.692GluTrp: 0.692 ± 0.649
2.768GluTyr: 2.768 ± 0.749
0.0GluXaa: 0.0 ± 0.0
Phe
4.844PheAla: 4.844 ± 1.647
0.692PheCys: 0.692 ± 0.649
6.92PheAsp: 6.92 ± 2.402
2.768PheGlu: 2.768 ± 1.806
2.076PhePhe: 2.076 ± 0.808
2.768PheGly: 2.768 ± 1.136
1.384PheHis: 1.384 ± 0.798
4.152PheIle: 4.152 ± 1.217
2.768PheLys: 2.768 ± 1.148
6.228PheLeu: 6.228 ± 2.031
0.0PheMet: 0.0 ± 0.0
6.92PheAsn: 6.92 ± 0.774
0.692PhePro: 0.692 ± 0.417
0.0PheGln: 0.0 ± 0.0
4.844PheArg: 4.844 ± 0.778
1.384PheSer: 1.384 ± 1.019
2.768PheThr: 2.768 ± 1.669
2.768PheVal: 2.768 ± 1.806
0.692PheTrp: 0.692 ± 0.417
2.768PheTyr: 2.768 ± 1.031
0.0PheXaa: 0.0 ± 0.0
Gly
1.384GlyAla: 1.384 ± 1.426
0.0GlyCys: 0.0 ± 0.0
4.152GlyAsp: 4.152 ± 1.355
5.536GlyGlu: 5.536 ± 1.287
2.076GlyPhe: 2.076 ± 1.946
5.536GlyGly: 5.536 ± 1.683
0.692GlyHis: 0.692 ± 0.417
3.46GlyIle: 3.46 ± 0.594
1.384GlyLys: 1.384 ± 0.656
6.92GlyLeu: 6.92 ± 1.901
1.384GlyMet: 1.384 ± 0.822
4.152GlyAsn: 4.152 ± 0.897
0.692GlyPro: 0.692 ± 0.915
2.768GlyGln: 2.768 ± 1.998
3.46GlyArg: 3.46 ± 2.172
4.844GlySer: 4.844 ± 0.88
2.076GlyThr: 2.076 ± 0.808
2.768GlyVal: 2.768 ± 1.136
0.0GlyTrp: 0.0 ± 0.0
2.768GlyTyr: 2.768 ± 1.204
0.0GlyXaa: 0.0 ± 0.0
His
0.692HisAla: 0.692 ± 0.864
0.0HisCys: 0.0 ± 0.0
1.384HisAsp: 1.384 ± 1.199
0.692HisGlu: 0.692 ± 0.417
0.692HisPhe: 0.692 ± 0.417
2.076HisGly: 2.076 ± 0.964
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
2.076HisLys: 2.076 ± 1.564
2.076HisLeu: 2.076 ± 1.18
0.0HisMet: 0.0 ± 0.0
0.692HisAsn: 0.692 ± 0.864
0.692HisPro: 0.692 ± 0.713
0.0HisGln: 0.0 ± 0.0
0.0HisArg: 0.0 ± 0.0
0.692HisSer: 0.692 ± 0.417
0.0HisThr: 0.0 ± 0.0
1.384HisVal: 1.384 ± 1.297
0.0HisTrp: 0.0 ± 0.0
1.384HisTyr: 1.384 ± 1.297
0.0HisXaa: 0.0 ± 0.0
Ile
2.076IleAla: 2.076 ± 1.267
0.0IleCys: 0.0 ± 0.0
2.768IleAsp: 2.768 ± 1.082
3.46IleGlu: 3.46 ± 0.995
4.152IlePhe: 4.152 ± 1.615
4.152IleGly: 4.152 ± 2.534
0.692IleHis: 0.692 ± 0.713
0.692IleIle: 0.692 ± 0.915
2.768IleLys: 2.768 ± 1.031
6.228IleLeu: 6.228 ± 1.824
0.0IleMet: 0.0 ± 0.0
6.228IleAsn: 6.228 ± 0.545
2.076IlePro: 2.076 ± 0.81
3.46IleGln: 3.46 ± 0.594
3.46IleArg: 3.46 ± 1.554
6.228IleSer: 6.228 ± 1.426
2.768IleThr: 2.768 ± 1.669
0.692IleVal: 0.692 ± 0.417
1.384IleTrp: 1.384 ± 1.019
1.384IleTyr: 1.384 ± 0.602
0.0IleXaa: 0.0 ± 0.0
Lys
4.152LysAla: 4.152 ± 2.864
0.692LysCys: 0.692 ± 0.649
2.768LysAsp: 2.768 ± 1.143
5.536LysGlu: 5.536 ± 1.748
4.844LysPhe: 4.844 ± 2.347
0.692LysGly: 0.692 ± 0.864
0.692LysHis: 0.692 ± 0.649
8.304LysIle: 8.304 ± 1.856
6.92LysLys: 6.92 ± 2.315
6.228LysLeu: 6.228 ± 2.541
4.152LysMet: 4.152 ± 1.964
2.768LysAsn: 2.768 ± 1.257
3.46LysPro: 3.46 ± 1.535
0.692LysGln: 0.692 ± 0.649
3.46LysArg: 3.46 ± 1.118
4.844LysSer: 4.844 ± 1.582
2.768LysThr: 2.768 ± 1.84
3.46LysVal: 3.46 ± 1.044
0.692LysTrp: 0.692 ± 0.915
3.46LysTyr: 3.46 ± 2.445
0.0LysXaa: 0.0 ± 0.0
Leu
4.152LeuAla: 4.152 ± 0.743
0.692LeuCys: 0.692 ± 0.417
4.844LeuAsp: 4.844 ± 1.687
0.692LeuGlu: 0.692 ± 0.417
2.076LeuPhe: 2.076 ± 1.305
4.844LeuGly: 4.844 ± 0.53
2.076LeuHis: 2.076 ± 1.18
3.46LeuIle: 3.46 ± 1.762
8.997LeuLys: 8.997 ± 2.422
6.228LeuLeu: 6.228 ± 2.871
1.384LeuMet: 1.384 ± 0.834
4.844LeuAsn: 4.844 ± 2.019
3.46LeuPro: 3.46 ± 1.509
7.612LeuGln: 7.612 ± 1.747
5.536LeuArg: 5.536 ± 1.422
7.612LeuSer: 7.612 ± 2.328
4.844LeuThr: 4.844 ± 1.233
2.076LeuVal: 2.076 ± 0.808
1.384LeuTrp: 1.384 ± 0.834
4.152LeuTyr: 4.152 ± 0.897
0.0LeuXaa: 0.0 ± 0.0
Met
1.384MetAla: 1.384 ± 0.99
0.0MetCys: 0.0 ± 0.0
0.692MetAsp: 0.692 ± 0.417
0.0MetGlu: 0.0 ± 0.0
0.692MetPhe: 0.692 ± 0.713
2.076MetGly: 2.076 ± 1.305
0.692MetHis: 0.692 ± 0.417
1.384MetIle: 1.384 ± 1.728
2.076MetLys: 2.076 ± 1.18
2.768MetLeu: 2.768 ± 1.257
0.0MetMet: 0.0 ± 0.0
2.076MetAsn: 2.076 ± 0.836
0.692MetPro: 0.692 ± 0.713
1.384MetGln: 1.384 ± 0.656
1.384MetArg: 1.384 ± 0.602
1.384MetSer: 1.384 ± 0.656
0.692MetThr: 0.692 ± 0.915
0.692MetVal: 0.692 ± 0.713
0.692MetTrp: 0.692 ± 0.915
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
5.536AsnAla: 5.536 ± 1.933
0.692AsnCys: 0.692 ± 0.915
5.536AsnAsp: 5.536 ± 1.795
2.076AsnGlu: 2.076 ± 1.029
4.844AsnPhe: 4.844 ± 0.778
1.384AsnGly: 1.384 ± 1.297
0.0AsnHis: 0.0 ± 0.0
5.536AsnIle: 5.536 ± 1.366
5.536AsnLys: 5.536 ± 1.486
6.228AsnLeu: 6.228 ± 1.926
2.076AsnMet: 2.076 ± 2.139
4.152AsnAsn: 4.152 ± 1.727
1.384AsnPro: 1.384 ± 0.656
3.46AsnGln: 3.46 ± 1.444
3.46AsnArg: 3.46 ± 2.534
7.612AsnSer: 7.612 ± 3.107
6.228AsnThr: 6.228 ± 2.182
3.46AsnVal: 3.46 ± 1.145
0.692AsnTrp: 0.692 ± 0.417
2.076AsnTyr: 2.076 ± 0.976
0.0AsnXaa: 0.0 ± 0.0
Pro
0.0ProAla: 0.0 ± 0.0
0.692ProCys: 0.692 ± 0.649
1.384ProAsp: 1.384 ± 0.602
6.92ProGlu: 6.92 ± 1.771
2.076ProPhe: 2.076 ± 0.808
2.076ProGly: 2.076 ± 0.81
1.384ProHis: 1.384 ± 1.084
2.768ProIle: 2.768 ± 1.257
5.536ProLys: 5.536 ± 1.608
3.46ProLeu: 3.46 ± 0.685
1.384ProMet: 1.384 ± 0.656
0.692ProAsn: 0.692 ± 0.417
0.692ProPro: 0.692 ± 0.864
1.384ProGln: 1.384 ± 1.199
2.076ProArg: 2.076 ± 0.964
3.46ProSer: 3.46 ± 1.444
2.076ProThr: 2.076 ± 1.305
4.844ProVal: 4.844 ± 2.563
0.0ProTrp: 0.0 ± 0.0
4.152ProTyr: 4.152 ± 2.36
0.0ProXaa: 0.0 ± 0.0
Gln
3.46GlnAla: 3.46 ± 1.044
0.0GlnCys: 0.0 ± 0.0
2.076GlnAsp: 2.076 ± 1.029
1.384GlnGlu: 1.384 ± 0.822
2.768GlnPhe: 2.768 ± 1.031
1.384GlnGly: 1.384 ± 0.656
0.0GlnHis: 0.0 ± 0.0
2.076GlnIle: 2.076 ± 1.305
3.46GlnLys: 3.46 ± 1.661
2.076GlnLeu: 2.076 ± 0.824
0.692GlnMet: 0.692 ± 0.417
6.92GlnAsn: 6.92 ± 3.464
2.768GlnPro: 2.768 ± 0.826
4.152GlnGln: 4.152 ± 1.858
3.46GlnArg: 3.46 ± 2.086
3.46GlnSer: 3.46 ± 0.594
1.384GlnThr: 1.384 ± 0.834
1.384GlnVal: 1.384 ± 0.656
1.384GlnTrp: 1.384 ± 0.656
1.384GlnTyr: 1.384 ± 0.656
0.0GlnXaa: 0.0 ± 0.0
Arg
1.384ArgAla: 1.384 ± 0.834
1.384ArgCys: 1.384 ± 1.297
3.46ArgAsp: 3.46 ± 2.086
2.076ArgGlu: 2.076 ± 1.029
5.536ArgPhe: 5.536 ± 1.224
2.768ArgGly: 2.768 ± 0.816
0.0ArgHis: 0.0 ± 0.0
3.46ArgIle: 3.46 ± 1.362
6.228ArgLys: 6.228 ± 3.336
5.536ArgLeu: 5.536 ± 2.356
0.692ArgMet: 0.692 ± 0.713
4.844ArgAsn: 4.844 ± 3.368
4.844ArgPro: 4.844 ± 1.649
0.692ArgGln: 0.692 ± 0.915
6.228ArgArg: 6.228 ± 7.229
2.076ArgSer: 2.076 ± 0.836
0.692ArgThr: 0.692 ± 0.417
2.076ArgVal: 2.076 ± 0.57
0.692ArgTrp: 0.692 ± 0.649
4.152ArgTyr: 4.152 ± 1.217
0.0ArgXaa: 0.0 ± 0.0
Ser
4.152SerAla: 4.152 ± 1.355
0.692SerCys: 0.692 ± 0.649
1.384SerAsp: 1.384 ± 0.834
1.384SerGlu: 1.384 ± 0.834
8.304SerPhe: 8.304 ± 2.043
3.46SerGly: 3.46 ± 1.195
1.384SerHis: 1.384 ± 0.822
6.228SerIle: 6.228 ± 1.217
5.536SerLys: 5.536 ± 1.422
4.152SerLeu: 4.152 ± 0.665
2.076SerMet: 2.076 ± 0.808
3.46SerAsn: 3.46 ± 1.535
4.844SerPro: 4.844 ± 1.787
4.844SerGln: 4.844 ± 2.393
4.152SerArg: 4.152 ± 1.322
6.228SerSer: 6.228 ± 2.216
7.612SerThr: 7.612 ± 2.488
6.228SerVal: 6.228 ± 1.002
1.384SerTrp: 1.384 ± 0.656
5.536SerTyr: 5.536 ± 0.825
0.0SerXaa: 0.0 ± 0.0
Thr
2.076ThrAla: 2.076 ± 0.824
0.0ThrCys: 0.0 ± 0.0
2.076ThrAsp: 2.076 ± 1.252
1.384ThrGlu: 1.384 ± 0.656
4.152ThrPhe: 4.152 ± 1.756
4.152ThrGly: 4.152 ± 1.433
1.384ThrHis: 1.384 ± 0.842
2.768ThrIle: 2.768 ± 0.958
3.46ThrLys: 3.46 ± 1.362
2.768ThrLeu: 2.768 ± 1.136
1.384ThrMet: 1.384 ± 0.882
5.536ThrAsn: 5.536 ± 1.54
4.152ThrPro: 4.152 ± 2.457
6.228ThrGln: 6.228 ± 1.834
3.46ThrArg: 3.46 ± 2.709
5.536ThrSer: 5.536 ± 2.295
5.536ThrThr: 5.536 ± 2.025
1.384ThrVal: 1.384 ± 0.834
0.692ThrTrp: 0.692 ± 0.417
0.692ThrTyr: 0.692 ± 0.649
0.0ThrXaa: 0.0 ± 0.0
Val
4.152ValAla: 4.152 ± 1.217
0.692ValCys: 0.692 ± 0.915
3.46ValAsp: 3.46 ± 1.512
2.768ValGlu: 2.768 ± 2.168
0.692ValPhe: 0.692 ± 0.713
4.844ValGly: 4.844 ± 1.647
0.0ValHis: 0.0 ± 0.0
1.384ValIle: 1.384 ± 0.602
0.692ValLys: 0.692 ± 0.915
4.152ValLeu: 4.152 ± 2.503
0.0ValMet: 0.0 ± 0.0
3.46ValAsn: 3.46 ± 2.086
6.92ValPro: 6.92 ± 1.911
1.384ValGln: 1.384 ± 0.656
1.384ValArg: 1.384 ± 0.602
8.997ValSer: 8.997 ± 2.431
2.076ValThr: 2.076 ± 0.808
5.536ValVal: 5.536 ± 2.116
0.0ValTrp: 0.0 ± 0.0
2.076ValTyr: 2.076 ± 0.976
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.692TrpCys: 0.692 ± 0.649
0.692TrpAsp: 0.692 ± 0.417
0.0TrpGlu: 0.0 ± 0.0
0.692TrpPhe: 0.692 ± 0.713
1.384TrpGly: 1.384 ± 0.842
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
1.384TrpLys: 1.384 ± 0.656
0.692TrpLeu: 0.692 ± 0.417
0.0TrpMet: 0.0 ± 0.0
0.692TrpAsn: 0.692 ± 0.417
0.0TrpPro: 0.0 ± 0.0
0.692TrpGln: 0.692 ± 0.649
0.0TrpArg: 0.0 ± 0.0
2.076TrpSer: 2.076 ± 1.443
1.384TrpThr: 1.384 ± 0.842
2.768TrpVal: 2.768 ± 1.311
0.0TrpTrp: 0.0 ± 0.0
0.692TrpTyr: 0.692 ± 0.417
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.768TyrAla: 2.768 ± 1.148
0.0TyrCys: 0.0 ± 0.0
2.768TyrAsp: 2.768 ± 1.757
2.076TyrGlu: 2.076 ± 0.976
2.768TyrPhe: 2.768 ± 1.136
2.076TyrGly: 2.076 ± 1.267
1.384TyrHis: 1.384 ± 1.084
4.152TyrIle: 4.152 ± 2.36
2.076TyrLys: 2.076 ± 1.18
4.152TyrLeu: 4.152 ± 1.01
0.0TyrMet: 0.0 ± 0.0
4.844TyrAsn: 4.844 ± 1.461
1.384TyrPro: 1.384 ± 1.297
0.692TyrGln: 0.692 ± 0.417
2.768TyrArg: 2.768 ± 1.669
6.92TyrSer: 6.92 ± 2.682
4.152TyrThr: 4.152 ± 0.93
2.076TyrVal: 2.076 ± 0.808
2.076TyrTrp: 2.076 ± 0.836
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (1446 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski