Amino acid dipepetide frequency for Canis familiaris papillomavirus 3

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.917AlaAla: 5.917 ± 1.041
0.845AlaCys: 0.845 ± 0.614
2.536AlaAsp: 2.536 ± 0.828
5.495AlaGlu: 5.495 ± 1.155
3.381AlaPhe: 3.381 ± 0.619
5.495AlaGly: 5.495 ± 3.575
2.959AlaHis: 2.959 ± 0.555
2.959AlaIle: 2.959 ± 1.227
2.959AlaLys: 2.959 ± 1.321
5.495AlaLeu: 5.495 ± 1.585
1.268AlaMet: 1.268 ± 0.398
1.268AlaAsn: 1.268 ± 0.663
5.072AlaPro: 5.072 ± 1.624
1.268AlaGln: 1.268 ± 0.957
3.381AlaArg: 3.381 ± 0.542
3.381AlaSer: 3.381 ± 0.883
3.804AlaThr: 3.804 ± 0.913
4.649AlaVal: 4.649 ± 1.388
0.423AlaTrp: 0.423 ± 0.317
0.845AlaTyr: 0.845 ± 0.635
0.0AlaXaa: 0.0 ± 0.0
Cys
2.959CysAla: 2.959 ± 1.92
1.268CysCys: 1.268 ± 1.527
0.845CysAsp: 0.845 ± 0.628
1.268CysGlu: 1.268 ± 0.619
0.845CysPhe: 0.845 ± 0.749
0.845CysGly: 0.845 ± 1.014
0.423CysHis: 0.423 ± 0.376
0.845CysIle: 0.845 ± 0.453
0.423CysLys: 0.423 ± 0.36
1.268CysLeu: 1.268 ± 0.965
0.423CysMet: 0.423 ± 0.317
1.268CysAsn: 1.268 ± 0.398
2.536CysPro: 2.536 ± 0.61
0.0CysGln: 0.0 ± 0.0
0.423CysArg: 0.423 ± 0.633
1.691CysSer: 1.691 ± 0.774
1.691CysThr: 1.691 ± 2.076
1.268CysVal: 1.268 ± 1.127
0.423CysTrp: 0.423 ± 0.376
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.804AspAla: 3.804 ± 0.571
0.423AspCys: 0.423 ± 0.317
2.536AspAsp: 2.536 ± 1.283
3.804AspGlu: 3.804 ± 1.634
0.845AspPhe: 0.845 ± 0.59
2.536AspGly: 2.536 ± 0.796
1.691AspHis: 1.691 ± 0.793
3.381AspIle: 3.381 ± 1.317
1.691AspLys: 1.691 ± 1.058
5.495AspLeu: 5.495 ± 1.495
1.691AspMet: 1.691 ± 0.608
4.649AspAsn: 4.649 ± 0.766
2.959AspPro: 2.959 ± 0.83
1.268AspGln: 1.268 ± 0.685
2.959AspArg: 2.959 ± 0.732
5.495AspSer: 5.495 ± 1.475
4.649AspThr: 4.649 ± 1.301
4.227AspVal: 4.227 ± 1.739
1.691AspTrp: 1.691 ± 0.987
1.691AspTyr: 1.691 ± 0.555
0.0AspXaa: 0.0 ± 0.0
Glu
4.649GluAla: 4.649 ± 1.315
0.845GluCys: 0.845 ± 0.453
5.495GluAsp: 5.495 ± 2.298
7.608GluGlu: 7.608 ± 2.181
2.536GluPhe: 2.536 ± 0.8
5.917GluGly: 5.917 ± 1.228
1.691GluHis: 1.691 ± 0.662
1.691GluIle: 1.691 ± 0.855
2.959GluLys: 2.959 ± 0.98
2.959GluLeu: 2.959 ± 0.758
0.845GluMet: 0.845 ± 0.5
1.268GluAsn: 1.268 ± 0.663
2.959GluPro: 2.959 ± 1.132
2.536GluGln: 2.536 ± 1.038
4.649GluArg: 4.649 ± 2.044
3.381GluSer: 3.381 ± 1.069
2.959GluThr: 2.959 ± 0.709
4.649GluVal: 4.649 ± 1.904
0.423GluTrp: 0.423 ± 0.317
1.268GluTyr: 1.268 ± 0.685
0.0GluXaa: 0.0 ± 0.0
Phe
2.113PheAla: 2.113 ± 0.998
1.268PheCys: 1.268 ± 0.652
3.804PheAsp: 3.804 ± 1.575
3.804PheGlu: 3.804 ± 1.914
2.536PhePhe: 2.536 ± 1.539
1.691PheGly: 1.691 ± 0.687
0.0PheHis: 0.0 ± 0.0
1.268PheIle: 1.268 ± 0.685
3.381PheLys: 3.381 ± 1.328
2.536PheLeu: 2.536 ± 0.551
0.0PheMet: 0.0 ± 0.0
1.268PheAsn: 1.268 ± 0.77
2.113PhePro: 2.113 ± 0.47
0.845PheGln: 0.845 ± 0.388
2.959PheArg: 2.959 ± 0.667
3.381PheSer: 3.381 ± 1.684
1.268PheThr: 1.268 ± 0.685
2.113PheVal: 2.113 ± 0.693
1.268PheTrp: 1.268 ± 0.398
0.845PheTyr: 0.845 ± 0.665
0.0PheXaa: 0.0 ± 0.0
Gly
4.227GlyAla: 4.227 ± 0.984
0.423GlyCys: 0.423 ± 0.376
3.381GlyAsp: 3.381 ± 1.133
6.34GlyGlu: 6.34 ± 0.961
0.845GlyPhe: 0.845 ± 0.59
8.03GlyGly: 8.03 ± 3.015
2.113GlyHis: 2.113 ± 0.992
3.804GlyIle: 3.804 ± 1.262
1.268GlyLys: 1.268 ± 0.687
7.185GlyLeu: 7.185 ± 0.962
0.845GlyMet: 0.845 ± 0.653
4.649GlyAsn: 4.649 ± 0.976
5.917GlyPro: 5.917 ± 2.812
2.113GlyGln: 2.113 ± 0.641
5.072GlyArg: 5.072 ± 0.915
6.34GlySer: 6.34 ± 2.604
5.072GlyThr: 5.072 ± 1.292
5.072GlyVal: 5.072 ± 1.723
0.0GlyTrp: 0.0 ± 0.0
2.536GlyTyr: 2.536 ± 0.713
0.0GlyXaa: 0.0 ± 0.0
His
2.113HisAla: 2.113 ± 0.395
1.268HisCys: 1.268 ± 0.619
0.845HisAsp: 0.845 ± 0.42
0.0HisGlu: 0.0 ± 0.0
0.845HisPhe: 0.845 ± 0.42
0.845HisGly: 0.845 ± 0.628
0.845HisHis: 0.845 ± 0.635
1.268HisIle: 1.268 ± 0.398
1.268HisLys: 1.268 ± 0.555
0.845HisLeu: 0.845 ± 0.453
0.0HisMet: 0.0 ± 0.0
0.845HisAsn: 0.845 ± 0.635
1.268HisPro: 1.268 ± 0.406
0.845HisGln: 0.845 ± 0.431
2.113HisArg: 2.113 ± 0.641
2.536HisSer: 2.536 ± 0.768
2.113HisThr: 2.113 ± 0.471
0.845HisVal: 0.845 ± 0.343
0.845HisTrp: 0.845 ± 0.388
1.691HisTyr: 1.691 ± 0.862
0.0HisXaa: 0.0 ± 0.0
Ile
1.691IleAla: 1.691 ± 0.836
1.691IleCys: 1.691 ± 0.527
1.691IleAsp: 1.691 ± 0.836
1.691IleGlu: 1.691 ± 0.563
2.113IlePhe: 2.113 ± 0.736
3.804IleGly: 3.804 ± 0.755
0.845IleHis: 0.845 ± 0.628
0.0IleIle: 0.0 ± 0.0
2.113IleLys: 2.113 ± 0.994
2.536IleLeu: 2.536 ± 0.53
0.845IleMet: 0.845 ± 0.635
2.113IleAsn: 2.113 ± 0.808
3.804IlePro: 3.804 ± 1.811
2.113IleGln: 2.113 ± 0.86
1.268IleArg: 1.268 ± 0.685
3.381IleSer: 3.381 ± 1.105
2.959IleThr: 2.959 ± 1.163
4.227IleVal: 4.227 ± 1.035
0.0IleTrp: 0.0 ± 0.0
0.423IleTyr: 0.423 ± 0.375
0.0IleXaa: 0.0 ± 0.0
Lys
1.268LysAla: 1.268 ± 0.406
0.423LysCys: 0.423 ± 0.375
0.845LysAsp: 0.845 ± 0.719
1.268LysGlu: 1.268 ± 0.667
2.113LysPhe: 2.113 ± 1.196
2.536LysGly: 2.536 ± 0.675
2.536LysHis: 2.536 ± 1.904
2.959LysIle: 2.959 ± 1.022
3.381LysLys: 3.381 ± 1.021
0.845LysLeu: 0.845 ± 0.453
0.845LysMet: 0.845 ± 0.702
2.959LysAsn: 2.959 ± 0.934
0.423LysPro: 0.423 ± 0.376
1.691LysGln: 1.691 ± 0.606
5.917LysArg: 5.917 ± 1.11
4.227LysSer: 4.227 ± 1.58
1.691LysThr: 1.691 ± 0.563
2.536LysVal: 2.536 ± 1.129
0.845LysTrp: 0.845 ± 0.388
1.691LysTyr: 1.691 ± 0.644
0.0LysXaa: 0.0 ± 0.0
Leu
5.917LeuAla: 5.917 ± 0.849
2.959LeuCys: 2.959 ± 3.04
5.072LeuAsp: 5.072 ± 1.138
5.917LeuGlu: 5.917 ± 1.754
2.959LeuPhe: 2.959 ± 1.002
6.762LeuGly: 6.762 ± 2.138
2.536LeuHis: 2.536 ± 0.536
3.381LeuIle: 3.381 ± 1.794
3.381LeuLys: 3.381 ± 0.717
6.34LeuLeu: 6.34 ± 0.872
2.536LeuMet: 2.536 ± 1.087
2.536LeuAsn: 2.536 ± 1.269
4.227LeuPro: 4.227 ± 0.772
5.495LeuGln: 5.495 ± 1.589
5.917LeuArg: 5.917 ± 1.438
5.917LeuSer: 5.917 ± 1.444
5.072LeuThr: 5.072 ± 0.55
3.381LeuVal: 3.381 ± 0.656
1.268LeuTrp: 1.268 ± 0.619
2.536LeuTyr: 2.536 ± 0.806
0.0LeuXaa: 0.0 ± 0.0
Met
0.845MetAla: 0.845 ± 0.753
0.423MetCys: 0.423 ± 0.317
1.268MetAsp: 1.268 ± 0.77
1.691MetGlu: 1.691 ± 0.527
0.423MetPhe: 0.423 ± 0.376
0.423MetGly: 0.423 ± 0.317
0.845MetHis: 0.845 ± 0.749
0.423MetIle: 0.423 ± 0.633
0.423MetLys: 0.423 ± 0.317
1.268MetLeu: 1.268 ± 0.952
0.423MetMet: 0.423 ± 0.376
0.0MetAsn: 0.0 ± 0.0
0.0MetPro: 0.0 ± 0.0
0.423MetGln: 0.423 ± 0.375
1.268MetArg: 1.268 ± 0.952
2.113MetSer: 2.113 ± 1.266
0.845MetThr: 0.845 ± 0.42
1.691MetVal: 1.691 ± 0.687
0.423MetTrp: 0.423 ± 0.375
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.804AsnAla: 3.804 ± 1.603
0.423AsnCys: 0.423 ± 0.375
2.536AsnAsp: 2.536 ± 0.772
2.536AsnGlu: 2.536 ± 0.796
1.268AsnPhe: 1.268 ± 0.356
2.113AsnGly: 2.113 ± 0.969
0.0AsnHis: 0.0 ± 0.0
3.381AsnIle: 3.381 ± 1.131
1.691AsnLys: 1.691 ± 0.905
2.113AsnLeu: 2.113 ± 1.58
0.423AsnMet: 0.423 ± 0.376
1.268AsnAsn: 1.268 ± 0.667
3.381AsnPro: 3.381 ± 1.044
2.113AsnGln: 2.113 ± 1.216
3.381AsnArg: 3.381 ± 0.955
2.536AsnSer: 2.536 ± 0.98
4.227AsnThr: 4.227 ± 0.959
1.691AsnVal: 1.691 ± 0.659
0.423AsnTrp: 0.423 ± 0.317
0.423AsnTyr: 0.423 ± 0.317
0.0AsnXaa: 0.0 ± 0.0
Pro
3.381ProAla: 3.381 ± 1.145
1.268ProCys: 1.268 ± 0.6
5.917ProAsp: 5.917 ± 1.477
3.804ProGlu: 3.804 ± 0.883
2.113ProPhe: 2.113 ± 0.488
4.649ProGly: 4.649 ± 2.368
0.423ProHis: 0.423 ± 0.581
1.268ProIle: 1.268 ± 1.079
3.381ProLys: 3.381 ± 1.002
8.03ProLeu: 8.03 ± 2.214
0.0ProMet: 0.0 ± 0.0
1.268ProAsn: 1.268 ± 0.711
7.608ProPro: 7.608 ± 1.69
1.691ProGln: 1.691 ± 1.154
2.536ProArg: 2.536 ± 1.314
5.495ProSer: 5.495 ± 2.297
4.649ProThr: 4.649 ± 1.648
5.072ProVal: 5.072 ± 1.704
0.423ProTrp: 0.423 ± 0.581
1.691ProTyr: 1.691 ± 0.603
0.0ProXaa: 0.0 ± 0.0
Gln
2.536GlnAla: 2.536 ± 0.404
0.423GlnCys: 0.423 ± 0.317
2.536GlnAsp: 2.536 ± 0.949
2.536GlnGlu: 2.536 ± 0.596
2.536GlnPhe: 2.536 ± 1.067
3.381GlnGly: 3.381 ± 1.021
0.845GlnHis: 0.845 ± 0.431
1.691GlnIle: 1.691 ± 0.967
2.113GlnLys: 2.113 ± 1.035
3.804GlnLeu: 3.804 ± 0.875
0.423GlnMet: 0.423 ± 0.376
2.113GlnAsn: 2.113 ± 1.216
2.536GlnPro: 2.536 ± 0.752
1.691GlnGln: 1.691 ± 1.124
2.959GlnArg: 2.959 ± 0.814
2.536GlnSer: 2.536 ± 0.79
2.536GlnThr: 2.536 ± 0.716
2.959GlnVal: 2.959 ± 0.609
0.845GlnTrp: 0.845 ± 0.431
0.845GlnTyr: 0.845 ± 0.665
0.0GlnXaa: 0.0 ± 0.0
Arg
5.917ArgAla: 5.917 ± 1.919
1.691ArgCys: 1.691 ± 0.774
1.691ArgAsp: 1.691 ± 0.707
2.536ArgGlu: 2.536 ± 0.767
2.536ArgPhe: 2.536 ± 1.082
7.185ArgGly: 7.185 ± 1.193
1.268ArgHis: 1.268 ± 0.922
2.536ArgIle: 2.536 ± 1.109
2.959ArgLys: 2.959 ± 0.786
6.762ArgLeu: 6.762 ± 1.595
0.423ArgMet: 0.423 ± 0.317
2.113ArgAsn: 2.113 ± 0.886
3.804ArgPro: 3.804 ± 1.375
2.536ArgGln: 2.536 ± 1.049
8.453ArgArg: 8.453 ± 2.378
4.227ArgSer: 4.227 ± 1.861
3.381ArgThr: 3.381 ± 1.139
7.185ArgVal: 7.185 ± 1.9
1.691ArgTrp: 1.691 ± 0.773
3.381ArgTyr: 3.381 ± 0.938
0.0ArgXaa: 0.0 ± 0.0
Ser
3.804SerAla: 3.804 ± 0.916
1.268SerCys: 1.268 ± 0.986
6.762SerAsp: 6.762 ± 0.84
3.804SerGlu: 3.804 ± 0.309
3.381SerPhe: 3.381 ± 1.137
8.453SerGly: 8.453 ± 1.833
1.691SerHis: 1.691 ± 0.606
2.113SerIle: 2.113 ± 1.219
1.691SerLys: 1.691 ± 1.011
8.876SerLeu: 8.876 ± 2.356
1.268SerMet: 1.268 ± 0.766
4.649SerAsn: 4.649 ± 1.209
4.227SerPro: 4.227 ± 0.934
5.495SerGln: 5.495 ± 1.741
2.959SerArg: 2.959 ± 1.032
8.453SerSer: 8.453 ± 3.173
6.762SerThr: 6.762 ± 0.983
5.072SerVal: 5.072 ± 1.124
0.845SerTrp: 0.845 ± 0.665
1.268SerTyr: 1.268 ± 0.986
0.0SerXaa: 0.0 ± 0.0
Thr
2.959ThrAla: 2.959 ± 0.555
2.959ThrCys: 2.959 ± 1.537
2.959ThrAsp: 2.959 ± 1.369
2.536ThrGlu: 2.536 ± 1.003
2.536ThrPhe: 2.536 ± 0.855
2.959ThrGly: 2.959 ± 0.717
0.423ThrHis: 0.423 ± 0.36
0.845ThrIle: 0.845 ± 0.388
2.536ThrLys: 2.536 ± 0.53
6.34ThrLeu: 6.34 ± 1.166
0.845ThrMet: 0.845 ± 0.431
3.381ThrAsn: 3.381 ± 0.652
4.227ThrPro: 4.227 ± 0.959
2.959ThrGln: 2.959 ± 0.982
4.649ThrArg: 4.649 ± 0.773
8.876ThrSer: 8.876 ± 1.555
5.072ThrThr: 5.072 ± 1.968
5.072ThrVal: 5.072 ± 1.857
0.845ThrTrp: 0.845 ± 0.431
2.959ThrTyr: 2.959 ± 1.404
0.0ThrXaa: 0.0 ± 0.0
Val
2.959ValAla: 2.959 ± 0.555
0.0ValCys: 0.0 ± 0.0
4.649ValAsp: 4.649 ± 1.32
2.959ValGlu: 2.959 ± 1.235
2.959ValPhe: 2.959 ± 1.051
5.072ValGly: 5.072 ± 1.664
1.268ValHis: 1.268 ± 0.555
2.536ValIle: 2.536 ± 1.122
1.691ValLys: 1.691 ± 1.124
6.762ValLeu: 6.762 ± 0.885
1.268ValMet: 1.268 ± 0.555
1.268ValAsn: 1.268 ± 0.786
5.917ValPro: 5.917 ± 2.506
5.072ValGln: 5.072 ± 1.545
7.185ValArg: 7.185 ± 3.432
6.34ValSer: 6.34 ± 1.797
4.227ValThr: 4.227 ± 1.212
5.072ValVal: 5.072 ± 2.295
0.845ValTrp: 0.845 ± 0.753
1.691ValTyr: 1.691 ± 0.626
0.0ValXaa: 0.0 ± 0.0
Trp
0.845TrpAla: 0.845 ± 0.431
0.423TrpCys: 0.423 ± 0.633
1.268TrpAsp: 1.268 ± 0.742
0.423TrpGlu: 0.423 ± 0.581
0.423TrpPhe: 0.423 ± 0.375
0.423TrpGly: 0.423 ± 0.376
0.0TrpHis: 0.0 ± 0.0
0.845TrpIle: 0.845 ± 0.59
1.268TrpLys: 1.268 ± 0.748
2.536TrpLeu: 2.536 ± 1.358
0.0TrpMet: 0.0 ± 0.0
0.845TrpAsn: 0.845 ± 0.388
0.0TrpPro: 0.0 ± 0.0
0.423TrpGln: 0.423 ± 0.375
0.845TrpArg: 0.845 ± 0.59
1.691TrpSer: 1.691 ± 0.592
0.845TrpThr: 0.845 ± 0.749
1.268TrpVal: 1.268 ± 0.685
0.0TrpTrp: 0.0 ± 0.0
0.845TrpTyr: 0.845 ± 0.431
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.691TyrAla: 1.691 ± 0.626
0.423TyrCys: 0.423 ± 0.581
0.845TyrAsp: 0.845 ± 0.453
1.268TyrGlu: 1.268 ± 0.806
1.268TyrPhe: 1.268 ± 0.6
2.113TyrGly: 2.113 ± 0.471
0.845TyrHis: 0.845 ± 0.343
2.113TyrIle: 2.113 ± 1.205
0.423TyrLys: 0.423 ± 0.317
2.113TyrLeu: 2.113 ± 0.998
0.423TyrMet: 0.423 ± 0.317
0.0TyrAsn: 0.0 ± 0.0
1.691TyrPro: 1.691 ± 1.011
1.268TyrGln: 1.268 ± 0.685
3.381TyrArg: 3.381 ± 1.222
1.268TyrSer: 1.268 ± 0.685
2.113TyrThr: 2.113 ± 0.641
1.691TyrVal: 1.691 ± 0.563
1.691TyrTrp: 1.691 ± 0.527
1.691TyrTyr: 1.691 ± 0.659
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (2367 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski