Amino acid dipepetide frequency for Sus scrofa papillomavirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.41AlaAla: 6.41 ± 1.467
1.832AlaCys: 1.832 ± 0.746
5.037AlaAsp: 5.037 ± 0.855
5.037AlaGlu: 5.037 ± 1.774
5.037AlaPhe: 5.037 ± 2.378
3.663AlaGly: 3.663 ± 0.894
0.916AlaHis: 0.916 ± 0.5
1.374AlaIle: 1.374 ± 0.75
4.121AlaLys: 4.121 ± 1.468
5.952AlaLeu: 5.952 ± 1.403
0.916AlaMet: 0.916 ± 0.466
0.916AlaAsn: 0.916 ± 0.6
2.747AlaPro: 2.747 ± 0.508
5.495AlaGln: 5.495 ± 0.94
2.747AlaArg: 2.747 ± 1.244
2.289AlaSer: 2.289 ± 0.912
6.41AlaThr: 6.41 ± 1.98
1.832AlaVal: 1.832 ± 0.694
0.458AlaTrp: 0.458 ± 0.421
1.832AlaTyr: 1.832 ± 0.999
0.0AlaXaa: 0.0 ± 0.0
Cys
0.916CysAla: 0.916 ± 0.467
0.916CysCys: 0.916 ± 0.6
2.289CysAsp: 2.289 ± 1.236
0.916CysGlu: 0.916 ± 0.368
0.458CysPhe: 0.458 ± 0.388
1.374CysGly: 1.374 ± 1.165
0.0CysHis: 0.0 ± 0.0
1.374CysIle: 1.374 ± 1.007
2.289CysLys: 2.289 ± 0.612
2.289CysLeu: 2.289 ± 0.968
0.0CysMet: 0.0 ± 0.0
0.458CysAsn: 0.458 ± 0.471
1.832CysPro: 1.832 ± 0.596
0.458CysGln: 0.458 ± 0.388
0.458CysArg: 0.458 ± 0.471
1.832CysSer: 1.832 ± 0.877
2.747CysThr: 2.747 ± 0.724
0.458CysVal: 0.458 ± 0.418
2.289CysTrp: 2.289 ± 0.968
0.458CysTyr: 0.458 ± 0.418
0.0CysXaa: 0.0 ± 0.0
Asp
3.205AspAla: 3.205 ± 1.377
1.374AspCys: 1.374 ± 0.408
2.747AspAsp: 2.747 ± 1.006
1.374AspGlu: 1.374 ± 0.538
2.747AspPhe: 2.747 ± 0.505
5.495AspGly: 5.495 ± 0.94
0.0AspHis: 0.0 ± 0.0
2.747AspIle: 2.747 ± 2.042
0.916AspLys: 0.916 ± 0.5
7.784AspLeu: 7.784 ± 1.395
1.374AspMet: 1.374 ± 0.618
4.579AspAsn: 4.579 ± 1.652
5.952AspPro: 5.952 ± 1.991
1.832AspGln: 1.832 ± 1.087
1.832AspArg: 1.832 ± 0.999
5.495AspSer: 5.495 ± 1.765
5.495AspThr: 5.495 ± 1.205
4.121AspVal: 4.121 ± 2.298
1.374AspTrp: 1.374 ± 0.895
1.832AspTyr: 1.832 ± 0.191
0.0AspXaa: 0.0 ± 0.0
Glu
4.121GluAla: 4.121 ± 2.085
0.916GluCys: 0.916 ± 0.777
1.832GluAsp: 1.832 ± 0.596
5.952GluGlu: 5.952 ± 1.504
1.374GluPhe: 1.374 ± 0.408
7.326GluGly: 7.326 ± 3.21
1.832GluHis: 1.832 ± 0.582
0.458GluIle: 0.458 ± 0.421
3.205GluLys: 3.205 ± 1.644
3.205GluLeu: 3.205 ± 0.693
1.832GluMet: 1.832 ± 0.933
1.374GluAsn: 1.374 ± 1.188
1.374GluPro: 1.374 ± 0.415
0.916GluGln: 0.916 ± 0.792
2.747GluArg: 2.747 ± 1.042
2.747GluSer: 2.747 ± 1.058
3.205GluThr: 3.205 ± 0.835
2.289GluVal: 2.289 ± 0.792
0.458GluTrp: 0.458 ± 0.388
0.916GluTyr: 0.916 ± 0.368
0.0GluXaa: 0.0 ± 0.0
Phe
1.374PheAla: 1.374 ± 0.783
1.374PheCys: 1.374 ± 1.007
3.205PheAsp: 3.205 ± 0.654
0.916PheGlu: 0.916 ± 0.49
2.747PhePhe: 2.747 ± 1.036
3.663PheGly: 3.663 ± 0.838
1.832PheHis: 1.832 ± 1.122
2.289PheIle: 2.289 ± 0.612
2.747PheLys: 2.747 ± 0.816
4.579PheLeu: 4.579 ± 0.791
1.832PheMet: 1.832 ± 0.458
0.916PheAsn: 0.916 ± 0.792
2.747PhePro: 2.747 ± 0.841
0.916PheGln: 0.916 ± 0.368
1.374PheArg: 1.374 ± 0.798
1.832PheSer: 1.832 ± 0.596
3.205PheThr: 3.205 ± 1.149
1.374PheVal: 1.374 ± 0.778
1.374PheTrp: 1.374 ± 0.645
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
3.205GlyAla: 3.205 ± 0.866
1.374GlyCys: 1.374 ± 0.408
7.784GlyAsp: 7.784 ± 1.513
8.242GlyGlu: 8.242 ± 2.167
0.916GlyPhe: 0.916 ± 0.5
10.073GlyGly: 10.073 ± 2.768
1.374GlyHis: 1.374 ± 0.798
5.037GlyIle: 5.037 ± 1.066
3.663GlyLys: 3.663 ± 0.824
5.037GlyLeu: 5.037 ± 1.741
0.458GlyMet: 0.458 ± 0.388
6.41GlyAsn: 6.41 ± 2.396
5.952GlyPro: 5.952 ± 1.766
5.037GlyGln: 5.037 ± 1.075
2.747GlyArg: 2.747 ± 1.006
5.495GlySer: 5.495 ± 2.364
5.952GlyThr: 5.952 ± 3.341
4.121GlyVal: 4.121 ± 1.345
1.374GlyTrp: 1.374 ± 0.777
2.289GlyTyr: 2.289 ± 0.995
0.0GlyXaa: 0.0 ± 0.0
His
1.374HisAla: 1.374 ± 0.645
0.916HisCys: 0.916 ± 0.467
0.916HisAsp: 0.916 ± 0.465
0.458HisGlu: 0.458 ± 0.421
1.374HisPhe: 1.374 ± 0.375
2.289HisGly: 2.289 ± 0.778
0.916HisHis: 0.916 ± 0.465
0.0HisIle: 0.0 ± 0.0
0.0HisLys: 0.0 ± 0.0
1.832HisLeu: 1.832 ± 0.984
0.916HisMet: 0.916 ± 0.777
0.916HisAsn: 0.916 ± 0.49
1.832HisPro: 1.832 ± 1.087
0.0HisGln: 0.0 ± 0.0
1.374HisArg: 1.374 ± 0.828
2.747HisSer: 2.747 ± 1.042
2.289HisThr: 2.289 ± 0.463
1.374HisVal: 1.374 ± 0.375
0.458HisTrp: 0.458 ± 0.396
0.916HisTyr: 0.916 ± 0.637
0.0HisXaa: 0.0 ± 0.0
Ile
0.916IleAla: 0.916 ± 0.5
0.458IleCys: 0.458 ± 0.396
0.916IleAsp: 0.916 ± 0.368
3.663IleGlu: 3.663 ± 0.894
1.832IlePhe: 1.832 ± 0.73
3.663IleGly: 3.663 ± 0.856
0.458IleHis: 0.458 ± 0.388
0.0IleIle: 0.0 ± 0.0
0.916IleLys: 0.916 ± 0.6
2.747IleLeu: 2.747 ± 1.512
0.0IleMet: 0.0 ± 0.0
0.916IleAsn: 0.916 ± 0.467
3.205IlePro: 3.205 ± 1.773
1.374IleGln: 1.374 ± 0.895
2.747IleArg: 2.747 ± 0.505
3.205IleSer: 3.205 ± 0.893
3.205IleThr: 3.205 ± 0.986
3.205IleVal: 3.205 ± 1.416
0.458IleTrp: 0.458 ± 0.418
0.458IleTyr: 0.458 ± 0.388
0.0IleXaa: 0.0 ± 0.0
Lys
1.832LysAla: 1.832 ± 0.596
0.458LysCys: 0.458 ± 0.418
2.289LysAsp: 2.289 ± 0.848
2.747LysGlu: 2.747 ± 1.304
2.289LysPhe: 2.289 ± 1.003
4.579LysGly: 4.579 ± 2.192
2.289LysHis: 2.289 ± 0.782
1.832LysIle: 1.832 ± 0.852
2.289LysLys: 2.289 ± 1.279
2.289LysLeu: 2.289 ± 1.192
0.458LysMet: 0.458 ± 0.396
0.458LysAsn: 0.458 ± 0.388
0.916LysPro: 0.916 ± 0.467
2.289LysGln: 2.289 ± 0.655
3.663LysArg: 3.663 ± 1.119
3.205LysSer: 3.205 ± 1.633
0.916LysThr: 0.916 ± 0.467
4.579LysVal: 4.579 ± 1.882
0.0LysTrp: 0.0 ± 0.0
1.832LysTyr: 1.832 ± 0.736
0.0LysXaa: 0.0 ± 0.0
Leu
5.037LeuAla: 5.037 ± 1.027
3.205LeuCys: 3.205 ± 1.443
5.495LeuAsp: 5.495 ± 1.103
3.205LeuGlu: 3.205 ± 1.416
4.121LeuPhe: 4.121 ± 1.107
9.615LeuGly: 9.615 ± 0.74
1.374LeuHis: 1.374 ± 0.375
2.289LeuIle: 2.289 ± 0.511
3.663LeuLys: 3.663 ± 1.433
7.326LeuLeu: 7.326 ± 2.344
0.916LeuMet: 0.916 ± 0.462
1.374LeuAsn: 1.374 ± 0.605
4.579LeuPro: 4.579 ± 1.352
6.41LeuGln: 6.41 ± 1.562
4.579LeuArg: 4.579 ± 1.015
7.326LeuSer: 7.326 ± 2.028
5.495LeuThr: 5.495 ± 0.714
5.037LeuVal: 5.037 ± 0.572
1.374LeuTrp: 1.374 ± 0.408
5.037LeuTyr: 5.037 ± 1.251
0.0LeuXaa: 0.0 ± 0.0
Met
0.916MetAla: 0.916 ± 0.569
0.0MetCys: 0.0 ± 0.0
1.832MetAsp: 1.832 ± 1.216
0.916MetGlu: 0.916 ± 0.467
1.374MetPhe: 1.374 ± 0.798
1.374MetGly: 1.374 ± 0.778
1.374MetHis: 1.374 ± 0.75
0.916MetIle: 0.916 ± 0.368
0.0MetLys: 0.0 ± 0.0
1.832MetLeu: 1.832 ± 0.582
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
0.916MetPro: 0.916 ± 0.5
0.0MetGln: 0.0 ± 0.0
0.458MetArg: 0.458 ± 0.396
0.916MetSer: 0.916 ± 0.777
1.832MetThr: 1.832 ± 0.582
1.832MetVal: 1.832 ± 1.128
0.916MetTrp: 0.916 ± 0.561
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.289AsnAla: 2.289 ± 0.94
1.374AsnCys: 1.374 ± 0.895
0.458AsnAsp: 0.458 ± 0.421
0.916AsnGlu: 0.916 ± 0.544
1.374AsnPhe: 1.374 ± 0.855
2.289AsnGly: 2.289 ± 0.339
0.0AsnHis: 0.0 ± 0.0
1.832AsnIle: 1.832 ± 1.242
3.205AsnLys: 3.205 ± 1.697
0.916AsnLeu: 0.916 ± 0.368
0.916AsnMet: 0.916 ± 0.368
1.374AsnAsn: 1.374 ± 1.188
1.832AsnPro: 1.832 ± 0.708
1.832AsnGln: 1.832 ± 1.216
2.289AsnArg: 2.289 ± 1.044
3.205AsnSer: 3.205 ± 1.633
4.121AsnThr: 4.121 ± 1.314
1.832AsnVal: 1.832 ± 0.596
0.916AsnTrp: 0.916 ± 0.368
0.458AsnTyr: 0.458 ± 0.388
0.0AsnXaa: 0.0 ± 0.0
Pro
5.952ProAla: 5.952 ± 1.204
1.832ProCys: 1.832 ± 0.928
5.952ProAsp: 5.952 ± 1.871
1.832ProGlu: 1.832 ± 0.814
2.289ProPhe: 2.289 ± 0.778
4.579ProGly: 4.579 ± 2.112
1.374ProHis: 1.374 ± 0.408
2.289ProIle: 2.289 ± 0.612
2.289ProLys: 2.289 ± 0.975
10.073ProLeu: 10.073 ± 2.355
0.916ProMet: 0.916 ± 0.842
2.289ProAsn: 2.289 ± 0.782
13.278ProPro: 13.278 ± 4.483
2.747ProGln: 2.747 ± 1.06
1.832ProArg: 1.832 ± 0.694
4.579ProSer: 4.579 ± 1.451
5.037ProThr: 5.037 ± 1.92
3.205ProVal: 3.205 ± 1.026
0.916ProTrp: 0.916 ± 0.835
1.832ProTyr: 1.832 ± 1.211
0.0ProXaa: 0.0 ± 0.0
Gln
3.663GlnAla: 3.663 ± 1.42
1.374GlnCys: 1.374 ± 0.661
0.916GlnAsp: 0.916 ± 0.465
2.289GlnGlu: 2.289 ± 0.349
3.205GlnPhe: 3.205 ± 0.585
4.121GlnGly: 4.121 ± 0.833
0.916GlnHis: 0.916 ± 0.637
1.374GlnIle: 1.374 ± 0.538
0.458GlnLys: 0.458 ± 0.418
3.205GlnLeu: 3.205 ± 2.151
1.374GlnMet: 1.374 ± 1.188
1.374GlnAsn: 1.374 ± 1.188
1.832GlnPro: 1.832 ± 0.574
1.374GlnGln: 1.374 ± 0.408
2.289GlnArg: 2.289 ± 1.347
2.747GlnSer: 2.747 ± 1.244
3.205GlnThr: 3.205 ± 0.478
2.289GlnVal: 2.289 ± 0.349
1.374GlnTrp: 1.374 ± 0.75
2.289GlnTyr: 2.289 ± 1.271
0.0GlnXaa: 0.0 ± 0.0
Arg
4.121ArgAla: 4.121 ± 0.646
2.747ArgCys: 2.747 ± 1.012
1.832ArgAsp: 1.832 ± 0.852
1.374ArgGlu: 1.374 ± 0.686
2.289ArgPhe: 2.289 ± 0.792
3.205ArgGly: 3.205 ± 1.446
1.832ArgHis: 1.832 ± 0.922
0.916ArgIle: 0.916 ± 0.5
4.121ArgLys: 4.121 ± 0.781
7.326ArgLeu: 7.326 ± 1.01
0.0ArgMet: 0.0 ± 0.362
1.374ArgAsn: 1.374 ± 1.165
6.868ArgPro: 6.868 ± 2.208
1.832ArgGln: 1.832 ± 0.984
9.158ArgArg: 9.158 ± 1.035
3.205ArgSer: 3.205 ± 0.873
3.205ArgThr: 3.205 ± 1.518
4.121ArgVal: 4.121 ± 1.704
0.916ArgTrp: 0.916 ± 0.467
0.916ArgTyr: 0.916 ± 0.467
0.0ArgXaa: 0.0 ± 0.0
Ser
3.205SerAla: 3.205 ± 0.669
0.458SerCys: 0.458 ± 0.396
6.41SerAsp: 6.41 ± 1.962
0.458SerGlu: 0.458 ± 0.418
3.205SerPhe: 3.205 ± 1.891
5.037SerGly: 5.037 ± 1.423
3.205SerHis: 3.205 ± 0.733
3.205SerIle: 3.205 ± 1.504
1.374SerLys: 1.374 ± 0.645
6.41SerLeu: 6.41 ± 1.824
0.916SerMet: 0.916 ± 0.5
3.205SerAsn: 3.205 ± 0.938
5.037SerPro: 5.037 ± 1.402
3.663SerGln: 3.663 ± 1.279
5.952SerArg: 5.952 ± 1.358
5.037SerSer: 5.037 ± 2.178
8.7SerThr: 8.7 ± 1.862
4.121SerVal: 4.121 ± 1.945
0.0SerTrp: 0.0 ± 0.0
0.916SerTyr: 0.916 ± 0.835
0.0SerXaa: 0.0 ± 0.0
Thr
8.7ThrAla: 8.7 ± 3.877
1.374ThrCys: 1.374 ± 0.828
4.579ThrAsp: 4.579 ± 0.724
3.663ThrGlu: 3.663 ± 1.165
1.374ThrPhe: 1.374 ± 0.503
5.952ThrGly: 5.952 ± 0.895
0.916ThrHis: 0.916 ± 0.49
2.747ThrIle: 2.747 ± 2.036
1.832ThrLys: 1.832 ± 1.128
5.495ThrLeu: 5.495 ± 1.008
2.747ThrMet: 2.747 ± 1.261
1.374ThrAsn: 1.374 ± 0.855
5.495ThrPro: 5.495 ± 2.168
2.747ThrGln: 2.747 ± 0.913
5.037ThrArg: 5.037 ± 1.199
8.242ThrSer: 8.242 ± 2.23
9.615ThrThr: 9.615 ± 3.994
6.41ThrVal: 6.41 ± 1.52
1.832ThrTrp: 1.832 ± 1.349
1.374ThrTyr: 1.374 ± 0.855
0.0ThrXaa: 0.0 ± 0.0
Val
4.121ValAla: 4.121 ± 1.759
1.832ValCys: 1.832 ± 0.746
3.205ValAsp: 3.205 ± 0.973
1.832ValGlu: 1.832 ± 1.023
1.832ValPhe: 1.832 ± 0.458
4.121ValGly: 4.121 ± 0.534
0.916ValHis: 0.916 ± 0.842
1.832ValIle: 1.832 ± 0.577
1.374ValLys: 1.374 ± 0.645
4.579ValLeu: 4.579 ± 0.973
0.458ValMet: 0.458 ± 0.453
1.832ValAsn: 1.832 ± 0.655
7.784ValPro: 7.784 ± 2.098
2.289ValGln: 2.289 ± 0.339
4.579ValArg: 4.579 ± 2.417
5.952ValSer: 5.952 ± 1.76
4.579ValThr: 4.579 ± 1.186
3.663ValVal: 3.663 ± 1.083
0.916ValTrp: 0.916 ± 0.569
2.289ValTyr: 2.289 ± 0.655
0.0ValXaa: 0.0 ± 0.0
Trp
1.374TrpAla: 1.374 ± 0.375
0.0TrpCys: 0.0 ± 0.0
2.747TrpAsp: 2.747 ± 1.534
0.458TrpGlu: 0.458 ± 0.418
0.0TrpPhe: 0.0 ± 0.0
1.832TrpGly: 1.832 ± 0.778
0.458TrpHis: 0.458 ± 0.421
0.916TrpIle: 0.916 ± 0.777
2.289TrpLys: 2.289 ± 1.192
1.374TrpLeu: 1.374 ± 0.659
0.0TrpMet: 0.0 ± 0.0
0.458TrpAsn: 0.458 ± 0.396
0.458TrpPro: 0.458 ± 0.471
0.458TrpGln: 0.458 ± 0.418
1.374TrpArg: 1.374 ± 1.04
0.458TrpSer: 0.458 ± 0.388
0.916TrpThr: 0.916 ± 0.544
1.832TrpVal: 1.832 ± 0.877
0.0TrpTrp: 0.0 ± 0.0
0.916TrpTyr: 0.916 ± 0.467
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.289TyrAla: 2.289 ± 0.782
0.0TyrCys: 0.0 ± 0.0
1.832TyrAsp: 1.832 ± 0.999
1.832TyrGlu: 1.832 ± 1.242
0.458TyrPhe: 0.458 ± 0.388
2.289TyrGly: 2.289 ± 0.995
0.916TyrHis: 0.916 ± 0.368
0.916TyrIle: 0.916 ± 0.561
0.458TyrLys: 0.458 ± 0.388
3.205TyrLeu: 3.205 ± 1.017
0.916TyrMet: 0.916 ± 0.544
1.832TyrAsn: 1.832 ± 1.023
0.458TyrPro: 0.458 ± 0.396
0.0TyrGln: 0.0 ± 0.0
4.579TyrArg: 4.579 ± 1.06
0.0TyrSer: 0.0 ± 0.0
1.374TyrThr: 1.374 ± 0.503
2.289TyrVal: 2.289 ± 0.53
0.916TyrTrp: 0.916 ± 0.544
2.289TyrTyr: 2.289 ± 1.408
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (2185 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski