Amino acid dipepetide frequency for Lucerne transient streak virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
9.082AlaAla: 9.082 ± 2.649
0.0AlaCys: 0.0 ± 0.0
3.027AlaAsp: 3.027 ± 1.252
7.568AlaGlu: 7.568 ± 2.851
0.0AlaPhe: 0.0 ± 0.0
5.55AlaGly: 5.55 ± 1.257
0.505AlaHis: 0.505 ± 0.308
3.532AlaIle: 3.532 ± 1.174
4.541AlaLys: 4.541 ± 1.865
8.073AlaLeu: 8.073 ± 1.386
3.027AlaMet: 3.027 ± 0.454
2.523AlaAsn: 2.523 ± 1.15
3.027AlaPro: 3.027 ± 0.92
0.0AlaGln: 0.0 ± 0.0
4.541AlaArg: 4.541 ± 0.881
7.064AlaSer: 7.064 ± 1.161
4.036AlaThr: 4.036 ± 1.313
4.541AlaVal: 4.541 ± 1.185
1.009AlaTrp: 1.009 ± 0.304
2.523AlaTyr: 2.523 ± 0.526
0.0AlaXaa: 0.0 ± 0.0
Cys
1.009CysAla: 1.009 ± 1.119
0.505CysCys: 0.505 ± 0.308
0.505CysAsp: 0.505 ± 0.308
1.514CysGlu: 1.514 ± 0.46
0.505CysPhe: 0.505 ± 0.308
1.009CysGly: 1.009 ± 0.304
0.505CysHis: 0.505 ± 1.171
0.505CysIle: 0.505 ± 0.308
3.532CysLys: 3.532 ± 0.918
1.514CysLeu: 1.514 ± 0.46
0.505CysMet: 0.505 ± 0.308
1.514CysAsn: 1.514 ± 1.193
0.505CysPro: 0.505 ± 0.308
0.505CysGln: 0.505 ± 0.446
0.505CysArg: 0.505 ± 1.171
3.027CysSer: 3.027 ± 0.84
1.514CysThr: 1.514 ± 0.652
1.009CysVal: 1.009 ± 0.304
0.0CysTrp: 0.0 ± 0.0
1.009CysTyr: 1.009 ± 1.119
0.0CysXaa: 0.0 ± 0.0
Asp
2.018AspAla: 2.018 ± 0.391
1.514AspCys: 1.514 ± 1.03
2.018AspAsp: 2.018 ± 0.671
5.55AspGlu: 5.55 ± 1.834
3.027AspPhe: 3.027 ± 0.454
4.036AspGly: 4.036 ± 1.465
0.0AspHis: 0.0 ± 0.0
2.018AspIle: 2.018 ± 1.503
1.514AspLys: 1.514 ± 0.42
8.577AspLeu: 8.577 ± 1.751
0.0AspMet: 0.0 ± 0.0
2.018AspAsn: 2.018 ± 2.184
4.036AspPro: 4.036 ± 0.976
0.505AspGln: 0.505 ± 0.308
2.018AspArg: 2.018 ± 0.733
3.027AspSer: 3.027 ± 2.09
1.514AspThr: 1.514 ± 0.46
1.009AspVal: 1.009 ± 1.119
3.027AspTrp: 3.027 ± 0.454
3.532AspTyr: 3.532 ± 3.209
0.0AspXaa: 0.0 ± 0.0
Glu
9.082GluAla: 9.082 ± 2.82
0.505GluCys: 0.505 ± 1.171
6.559GluAsp: 6.559 ± 0.915
6.054GluGlu: 6.054 ± 2.167
1.514GluPhe: 1.514 ± 0.46
5.55GluGly: 5.55 ± 1.158
0.505GluHis: 0.505 ± 0.308
5.045GluIle: 5.045 ± 1.46
4.036GluLys: 4.036 ± 1.674
6.054GluLeu: 6.054 ± 2.651
0.0GluMet: 0.0 ± 0.0
0.505GluAsn: 0.505 ± 0.308
5.55GluPro: 5.55 ± 0.983
1.514GluGln: 1.514 ± 0.925
2.018GluArg: 2.018 ± 1.233
4.541GluSer: 4.541 ± 2.075
6.054GluThr: 6.054 ± 1.824
5.045GluVal: 5.045 ± 0.911
0.505GluTrp: 0.505 ± 0.308
1.514GluTyr: 1.514 ± 0.42
0.0GluXaa: 0.0 ± 0.0
Phe
3.532PheAla: 3.532 ± 0.945
1.009PheCys: 1.009 ± 1.119
2.018PheAsp: 2.018 ± 1.503
1.009PheGlu: 1.009 ± 0.617
0.0PhePhe: 0.0 ± 0.0
2.018PheGly: 2.018 ± 0.671
0.0PheHis: 0.0 ± 0.0
1.514PheIle: 1.514 ± 0.46
0.505PheLys: 0.505 ± 0.308
1.514PheLeu: 1.514 ± 0.46
0.505PheMet: 0.505 ± 0.833
0.505PheAsn: 0.505 ± 0.576
2.018PhePro: 2.018 ± 0.671
1.009PheGln: 1.009 ± 0.617
3.027PheArg: 3.027 ± 1.252
1.514PheSer: 1.514 ± 1.03
1.514PheThr: 1.514 ± 1.728
1.514PheVal: 1.514 ± 0.42
0.0PheTrp: 0.0 ± 0.0
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
4.036GlyAla: 4.036 ± 0.94
3.532GlyCys: 3.532 ± 0.736
2.523GlyAsp: 2.523 ± 0.956
8.577GlyGlu: 8.577 ± 2.318
4.036GlyPhe: 4.036 ± 1.313
4.036GlyGly: 4.036 ± 1.07
1.514GlyHis: 1.514 ± 0.925
1.514GlyIle: 1.514 ± 0.46
6.054GlyLys: 6.054 ± 1.215
4.036GlyLeu: 4.036 ± 1.342
2.018GlyMet: 2.018 ± 0.671
1.514GlyAsn: 1.514 ± 0.42
2.018GlyPro: 2.018 ± 0.608
1.514GlyGln: 1.514 ± 1.03
6.559GlyArg: 6.559 ± 1.7
5.55GlySer: 5.55 ± 0.933
7.568GlyThr: 7.568 ± 1.578
6.559GlyVal: 6.559 ± 2.168
1.009GlyTrp: 1.009 ± 0.304
2.523GlyTyr: 2.523 ± 0.665
0.0GlyXaa: 0.0 ± 0.0
His
0.505HisAla: 0.505 ± 0.308
0.0HisCys: 0.0 ± 0.0
0.505HisAsp: 0.505 ± 0.308
2.018HisGlu: 2.018 ± 0.608
0.0HisPhe: 0.0 ± 0.0
1.009HisGly: 1.009 ± 0.304
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
0.0HisLys: 0.0 ± 0.0
1.009HisLeu: 1.009 ± 0.304
0.0HisMet: 0.0 ± 0.499
0.0HisAsn: 0.0 ± 0.0
1.514HisPro: 1.514 ± 0.925
0.0HisGln: 0.0 ± 0.0
0.505HisArg: 0.505 ± 1.171
0.505HisSer: 0.505 ± 0.308
3.027HisThr: 3.027 ± 0.777
1.009HisVal: 1.009 ± 0.304
0.0HisTrp: 0.0 ± 0.0
0.505HisTyr: 0.505 ± 1.171
0.0HisXaa: 0.0 ± 0.0
Ile
5.55IleAla: 5.55 ± 1.889
0.505IleCys: 0.505 ± 1.171
3.532IleAsp: 3.532 ± 0.725
2.523IleGlu: 2.523 ± 0.995
0.505IlePhe: 0.505 ± 0.308
2.018IleGly: 2.018 ± 0.671
0.0IleHis: 0.0 ± 0.0
0.505IleIle: 0.505 ± 0.308
2.523IleLys: 2.523 ± 0.665
0.505IleLeu: 0.505 ± 0.308
0.0IleMet: 0.0 ± 0.0
2.018IleAsn: 2.018 ± 0.391
6.054IlePro: 6.054 ± 2.018
1.009IleGln: 1.009 ± 0.533
2.018IleArg: 2.018 ± 1.503
6.054IleSer: 6.054 ± 0.519
0.505IleThr: 0.505 ± 0.576
6.559IleVal: 6.559 ± 2.137
0.505IleTrp: 0.505 ± 1.171
2.018IleTyr: 2.018 ± 0.391
0.0IleXaa: 0.0 ± 0.0
Lys
5.045LysAla: 5.045 ± 0.923
0.505LysCys: 0.505 ± 0.308
2.523LysAsp: 2.523 ± 0.995
3.027LysGlu: 3.027 ± 0.777
1.514LysPhe: 1.514 ± 0.42
6.559LysGly: 6.559 ± 1.544
1.009LysHis: 1.009 ± 0.533
1.514LysIle: 1.514 ± 2.269
3.027LysLys: 3.027 ± 1.38
6.054LysLeu: 6.054 ± 2.25
1.009LysMet: 1.009 ± 0.304
1.514LysAsn: 1.514 ± 0.42
3.532LysPro: 3.532 ± 1.443
1.514LysGln: 1.514 ± 0.42
3.532LysArg: 3.532 ± 0.796
7.064LysSer: 7.064 ± 2.469
1.009LysThr: 1.009 ± 0.533
6.559LysVal: 6.559 ± 1.229
2.523LysTrp: 2.523 ± 0.532
1.009LysTyr: 1.009 ± 0.617
0.0LysXaa: 0.0 ± 0.0
Leu
6.054LeuAla: 6.054 ± 2.276
2.523LeuCys: 2.523 ± 0.665
7.568LeuAsp: 7.568 ± 1.578
3.532LeuGlu: 3.532 ± 0.725
3.532LeuPhe: 3.532 ± 0.956
4.036LeuGly: 4.036 ± 1.041
0.0LeuHis: 0.0 ± 0.0
4.036LeuIle: 4.036 ± 1.342
5.045LeuLys: 5.045 ± 1.331
9.586LeuLeu: 9.586 ± 2.735
1.514LeuMet: 1.514 ± 0.86
3.532LeuAsn: 3.532 ± 0.796
5.045LeuPro: 5.045 ± 1.283
3.027LeuGln: 3.027 ± 0.84
4.036LeuArg: 4.036 ± 0.669
8.073LeuSer: 8.073 ± 1.291
4.541LeuThr: 4.541 ± 1.113
7.064LeuVal: 7.064 ± 1.9
3.027LeuTrp: 3.027 ± 0.84
3.532LeuTyr: 3.532 ± 0.796
0.0LeuXaa: 0.0 ± 0.0
Met
1.009MetAla: 1.009 ± 0.533
0.0MetCys: 0.0 ± 0.0
1.009MetAsp: 1.009 ± 0.304
0.0MetGlu: 0.0 ± 0.0
1.009MetPhe: 1.009 ± 0.304
1.514MetGly: 1.514 ± 0.652
0.0MetHis: 0.0 ± 0.0
1.009MetIle: 1.009 ± 0.304
0.505MetLys: 0.505 ± 0.308
3.027MetLeu: 3.027 ± 0.912
0.0MetMet: 0.0 ± 0.0
1.009MetAsn: 1.009 ± 0.304
1.514MetPro: 1.514 ± 1.193
0.0MetGln: 0.0 ± 0.0
1.514MetArg: 1.514 ± 0.652
0.505MetSer: 0.505 ± 0.576
2.018MetThr: 2.018 ± 0.608
0.505MetVal: 0.505 ± 0.576
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.514AsnAla: 1.514 ± 0.652
1.009AsnCys: 1.009 ± 0.304
0.505AsnAsp: 0.505 ± 1.171
0.505AsnGlu: 0.505 ± 0.308
2.523AsnPhe: 2.523 ± 0.995
2.018AsnGly: 2.018 ± 0.671
0.0AsnHis: 0.0 ± 0.0
3.532AsnIle: 3.532 ± 1.174
1.009AsnLys: 1.009 ± 0.617
4.036AsnLeu: 4.036 ± 0.781
1.009AsnMet: 1.009 ± 0.304
3.027AsnAsn: 3.027 ± 0.92
2.523AsnPro: 2.523 ± 0.665
0.0AsnGln: 0.0 ± 0.0
3.532AsnArg: 3.532 ± 0.796
3.532AsnSer: 3.532 ± 1.174
2.018AsnThr: 2.018 ± 1.725
1.514AsnVal: 1.514 ± 1.03
0.0AsnTrp: 0.0 ± 0.0
1.009AsnTyr: 1.009 ± 0.304
0.0AsnXaa: 0.0 ± 0.0
Pro
6.054ProAla: 6.054 ± 1.766
1.514ProCys: 1.514 ± 0.652
3.532ProAsp: 3.532 ± 1.174
2.523ProGlu: 2.523 ± 0.665
0.0ProPhe: 0.0 ± 0.0
5.55ProGly: 5.55 ± 0.884
2.523ProHis: 2.523 ± 0.526
1.514ProIle: 1.514 ± 0.652
3.532ProLys: 3.532 ± 0.945
4.036ProLeu: 4.036 ± 1.041
1.009ProMet: 1.009 ± 0.304
1.514ProAsn: 1.514 ± 0.46
3.532ProPro: 3.532 ± 1.825
3.027ProGln: 3.027 ± 0.912
1.514ProArg: 1.514 ± 0.925
7.568ProSer: 7.568 ± 2.139
2.018ProThr: 2.018 ± 1.079
3.027ProVal: 3.027 ± 0.454
1.009ProTrp: 1.009 ± 0.533
0.505ProTyr: 0.505 ± 1.171
0.0ProXaa: 0.0 ± 0.0
Gln
2.523GlnAla: 2.523 ± 0.532
0.0GlnCys: 0.0 ± 0.0
0.0GlnAsp: 0.0 ± 0.0
1.009GlnGlu: 1.009 ± 0.304
0.505GlnPhe: 0.505 ± 0.308
2.018GlnGly: 2.018 ± 0.391
0.505GlnHis: 0.505 ± 0.308
1.009GlnIle: 1.009 ± 1.119
4.036GlnLys: 4.036 ± 0.82
2.523GlnLeu: 2.523 ± 0.532
0.0GlnMet: 0.0 ± 0.0
2.018GlnAsn: 2.018 ± 0.608
1.009GlnPro: 1.009 ± 0.304
2.018GlnGln: 2.018 ± 0.608
1.514GlnArg: 1.514 ± 1.275
5.045GlnSer: 5.045 ± 1.959
1.009GlnThr: 1.009 ± 0.304
2.018GlnVal: 2.018 ± 0.733
1.514GlnTrp: 1.514 ± 0.42
0.505GlnTyr: 0.505 ± 0.308
0.0GlnXaa: 0.0 ± 0.0
Arg
1.009ArgAla: 1.009 ± 1.298
2.018ArgCys: 2.018 ± 1.259
2.523ArgAsp: 2.523 ± 2.204
2.523ArgGlu: 2.523 ± 1.541
3.027ArgPhe: 3.027 ± 0.777
6.054ArgGly: 6.054 ± 1.461
1.514ArgHis: 1.514 ± 0.42
4.036ArgIle: 4.036 ± 1.342
4.036ArgLys: 4.036 ± 1.559
5.045ArgLeu: 5.045 ± 1.351
1.009ArgMet: 1.009 ± 0.533
1.009ArgAsn: 1.009 ± 1.298
2.018ArgPro: 2.018 ± 0.608
2.523ArgGln: 2.523 ± 1.118
3.532ArgArg: 3.532 ± 1.443
2.018ArgSer: 2.018 ± 0.997
0.505ArgThr: 0.505 ± 0.576
5.55ArgVal: 5.55 ± 0.631
1.514ArgTrp: 1.514 ± 1.066
4.036ArgTyr: 4.036 ± 0.669
0.0ArgXaa: 0.0 ± 0.0
Ser
3.532SerAla: 3.532 ± 0.796
0.0SerCys: 0.0 ± 0.0
6.054SerAsp: 6.054 ± 1.634
6.054SerGlu: 6.054 ± 1.222
1.009SerPhe: 1.009 ± 1.298
8.073SerGly: 8.073 ± 1.802
1.009SerHis: 1.009 ± 1.119
2.018SerIle: 2.018 ± 0.391
5.55SerLys: 5.55 ± 0.598
7.064SerLeu: 7.064 ± 1.532
2.523SerMet: 2.523 ± 1.065
4.541SerAsn: 4.541 ± 0.812
4.036SerPro: 4.036 ± 1.115
6.559SerGln: 6.559 ± 2.606
4.541SerArg: 4.541 ± 0.737
15.641SerSer: 15.641 ± 4.408
7.064SerThr: 7.064 ± 2.62
8.073SerVal: 8.073 ± 1.68
3.027SerTrp: 3.027 ± 0.454
3.027SerTyr: 3.027 ± 0.84
0.0SerXaa: 0.0 ± 0.0
Thr
3.027ThrAla: 3.027 ± 0.92
2.018ThrCys: 2.018 ± 0.391
3.027ThrAsp: 3.027 ± 1.156
5.045ThrGlu: 5.045 ± 1.283
0.0ThrPhe: 0.0 ± 0.0
4.541ThrGly: 4.541 ± 0.744
0.0ThrHis: 0.0 ± 0.0
2.523ThrIle: 2.523 ± 0.526
2.018ThrLys: 2.018 ± 0.733
3.027ThrLeu: 3.027 ± 0.893
0.505ThrMet: 0.505 ± 0.576
2.523ThrAsn: 2.523 ± 0.665
4.036ThrPro: 4.036 ± 1.465
3.027ThrGln: 3.027 ± 1.621
0.505ThrArg: 0.505 ± 0.576
7.064ThrSer: 7.064 ± 0.614
5.55ThrThr: 5.55 ± 1.199
4.036ThrVal: 4.036 ± 0.976
0.0ThrTrp: 0.0 ± 0.0
2.523ThrTyr: 2.523 ± 1.389
0.0ThrXaa: 0.0 ± 0.0
Val
5.045ValAla: 5.045 ± 1.052
2.523ValCys: 2.523 ± 0.526
2.018ValAsp: 2.018 ± 3.433
7.568ValGlu: 7.568 ± 2.605
1.009ValPhe: 1.009 ± 0.617
7.568ValGly: 7.568 ± 1.359
2.018ValHis: 2.018 ± 0.608
5.55ValIle: 5.55 ± 0.631
3.532ValLys: 3.532 ± 1.272
7.568ValLeu: 7.568 ± 1.996
1.009ValMet: 1.009 ± 0.304
2.523ValAsn: 2.523 ± 0.665
2.018ValPro: 2.018 ± 0.671
1.009ValGln: 1.009 ± 1.119
7.064ValArg: 7.064 ± 1.483
4.541ValSer: 4.541 ± 1.26
2.018ValThr: 2.018 ± 0.997
4.036ValVal: 4.036 ± 1.57
0.505ValTrp: 0.505 ± 0.576
3.027ValTyr: 3.027 ± 2.067
0.0ValXaa: 0.0 ± 0.0
Trp
1.514TrpAla: 1.514 ± 0.42
0.505TrpCys: 0.505 ± 0.308
0.0TrpAsp: 0.0 ± 0.0
3.027TrpGlu: 3.027 ± 0.84
0.505TrpPhe: 0.505 ± 1.171
0.505TrpGly: 0.505 ± 0.576
0.0TrpHis: 0.0 ± 0.0
1.009TrpIle: 1.009 ± 0.304
2.018TrpLys: 2.018 ± 0.391
0.505TrpLeu: 0.505 ± 0.576
0.0TrpMet: 0.0 ± 0.0
0.505TrpAsn: 0.505 ± 0.576
1.009TrpPro: 1.009 ± 0.617
2.018TrpGln: 2.018 ± 0.671
2.018TrpArg: 2.018 ± 0.997
4.541TrpSer: 4.541 ± 0.744
0.0TrpThr: 0.0 ± 0.0
0.505TrpVal: 0.505 ± 0.446
1.009TrpTrp: 1.009 ± 0.304
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.027TyrAla: 3.027 ± 0.92
1.009TyrCys: 1.009 ± 0.617
1.514TyrAsp: 1.514 ± 0.46
2.523TyrGlu: 2.523 ± 0.526
0.505TyrPhe: 0.505 ± 0.308
3.027TyrGly: 3.027 ± 0.84
1.009TyrHis: 1.009 ± 0.304
2.523TyrIle: 2.523 ± 1.43
3.027TyrLys: 3.027 ± 0.84
5.55TyrLeu: 5.55 ± 0.598
0.0TyrMet: 0.0 ± 0.0
0.505TyrAsn: 0.505 ± 1.171
0.505TyrPro: 0.505 ± 0.308
0.0TyrGln: 0.0 ± 0.0
1.009TyrArg: 1.009 ± 1.119
2.523TyrSer: 2.523 ± 2.104
1.514TyrThr: 1.514 ± 3.512
2.018TyrVal: 2.018 ± 0.965
1.009TyrTrp: 1.009 ± 0.304
0.505TyrTyr: 0.505 ± 1.171
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (1983 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski