Amino acid dipepetide frequency for Pepper cryptic virus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.513AlaAla: 5.513 ± 1.042
0.0AlaCys: 0.0 ± 0.0
5.513AlaAsp: 5.513 ± 2.69
4.41AlaGlu: 4.41 ± 1.822
6.615AlaPhe: 6.615 ± 3.034
3.308AlaGly: 3.308 ± 2.341
2.205AlaHis: 2.205 ± 1.735
7.718AlaIle: 7.718 ± 2.167
3.308AlaLys: 3.308 ± 2.341
5.513AlaLeu: 5.513 ± 2.69
0.0AlaMet: 0.0 ± 0.0
3.308AlaAsn: 3.308 ± 0.955
3.308AlaPro: 3.308 ± 0.693
3.308AlaGln: 3.308 ± 0.955
3.308AlaArg: 3.308 ± 0.955
2.205AlaSer: 2.205 ± 1.735
7.718AlaThr: 7.718 ± 1.129
4.41AlaVal: 4.41 ± 1.822
1.103AlaTrp: 1.103 ± 0.868
5.513AlaTyr: 5.513 ± 1.042
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
2.205CysCys: 2.205 ± 0.087
2.205CysAsp: 2.205 ± 0.087
0.0CysGlu: 0.0 ± 0.0
2.205CysPhe: 2.205 ± 0.087
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
1.103CysIle: 1.103 ± 0.868
1.103CysLys: 1.103 ± 0.78
1.103CysLeu: 1.103 ± 0.78
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
1.103CysArg: 1.103 ± 0.78
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
1.103CysVal: 1.103 ± 0.868
1.103CysTrp: 1.103 ± 0.868
1.103CysTyr: 1.103 ± 0.78
0.0CysXaa: 0.0 ± 0.0
Asp
4.41AspAla: 4.41 ± 0.174
1.103AspCys: 1.103 ± 0.868
3.308AspAsp: 3.308 ± 0.955
3.308AspGlu: 3.308 ± 0.693
2.205AspPhe: 2.205 ± 0.087
3.308AspGly: 3.308 ± 0.955
0.0AspHis: 0.0 ± 0.0
3.308AspIle: 3.308 ± 0.955
2.205AspLys: 2.205 ± 0.087
8.82AspLeu: 8.82 ± 1.299
1.103AspMet: 1.103 ± 0.868
0.0AspAsn: 0.0 ± 0.0
2.205AspPro: 2.205 ± 1.561
2.205AspGln: 2.205 ± 0.087
4.41AspArg: 4.41 ± 1.822
2.205AspSer: 2.205 ± 1.561
2.205AspThr: 2.205 ± 1.735
4.41AspVal: 4.41 ± 3.121
4.41AspTrp: 4.41 ± 0.174
4.41AspTyr: 4.41 ± 1.822
0.0AspXaa: 0.0 ± 0.0
Glu
4.41GluAla: 4.41 ± 1.822
1.103GluCys: 1.103 ± 0.78
3.308GluAsp: 3.308 ± 2.603
3.308GluGlu: 3.308 ± 0.693
3.308GluPhe: 3.308 ± 0.693
6.615GluGly: 6.615 ± 3.034
2.205GluHis: 2.205 ± 1.561
8.82GluIle: 8.82 ± 1.299
4.41GluLys: 4.41 ± 0.174
4.41GluLeu: 4.41 ± 3.121
0.0GluMet: 0.0 ± 0.0
4.41GluAsn: 4.41 ± 1.473
2.205GluPro: 2.205 ± 1.735
2.205GluGln: 2.205 ± 1.561
2.205GluArg: 2.205 ± 1.735
1.103GluSer: 1.103 ± 0.78
3.308GluThr: 3.308 ± 0.955
3.308GluVal: 3.308 ± 0.955
0.0GluTrp: 0.0 ± 0.0
2.205GluTyr: 2.205 ± 0.087
0.0GluXaa: 0.0 ± 0.0
Phe
3.308PheAla: 3.308 ± 0.955
1.103PheCys: 1.103 ± 0.868
5.513PheAsp: 5.513 ± 0.606
3.308PheGlu: 3.308 ± 2.341
1.103PhePhe: 1.103 ± 0.868
2.205PheGly: 2.205 ± 0.087
1.103PheHis: 1.103 ± 0.78
2.205PheIle: 2.205 ± 0.087
3.308PheLys: 3.308 ± 0.955
3.308PheLeu: 3.308 ± 0.693
0.0PheMet: 0.0 ± 0.0
1.103PheAsn: 1.103 ± 0.868
5.513PhePro: 5.513 ± 0.606
0.0PheGln: 0.0 ± 0.0
4.41PheArg: 4.41 ± 0.174
0.0PheSer: 0.0 ± 0.0
4.41PheThr: 4.41 ± 0.174
0.0PheVal: 0.0 ± 0.0
0.0PheTrp: 0.0 ± 0.0
1.103PheTyr: 1.103 ± 0.78
0.0PheXaa: 0.0 ± 0.0
Gly
3.308GlyAla: 3.308 ± 0.955
1.103GlyCys: 1.103 ± 0.78
1.103GlyAsp: 1.103 ± 0.78
6.615GlyGlu: 6.615 ± 1.386
1.103GlyPhe: 1.103 ± 0.868
4.41GlyGly: 4.41 ± 1.473
1.103GlyHis: 1.103 ± 0.868
5.513GlyIle: 5.513 ± 2.254
1.103GlyLys: 1.103 ± 0.868
1.103GlyLeu: 1.103 ± 0.868
0.0GlyMet: 0.0 ± 0.0
3.308GlyAsn: 3.308 ± 0.693
4.41GlyPro: 4.41 ± 1.473
0.0GlyGln: 0.0 ± 0.0
3.308GlyArg: 3.308 ± 0.693
7.718GlySer: 7.718 ± 0.519
4.41GlyThr: 4.41 ± 1.473
3.308GlyVal: 3.308 ± 2.341
2.205GlyTrp: 2.205 ± 0.087
4.41GlyTyr: 4.41 ± 1.473
0.0GlyXaa: 0.0 ± 0.0
His
2.205HisAla: 2.205 ± 1.735
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
2.205HisGlu: 2.205 ± 1.735
1.103HisPhe: 1.103 ± 0.78
1.103HisGly: 1.103 ± 0.78
0.0HisHis: 0.0 ± 0.0
6.615HisIle: 6.615 ± 0.262
2.205HisLys: 2.205 ± 1.561
2.205HisLeu: 2.205 ± 0.087
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
1.103HisPro: 1.103 ± 0.78
1.103HisGln: 1.103 ± 0.868
2.205HisArg: 2.205 ± 0.087
0.0HisSer: 0.0 ± 0.0
1.103HisThr: 1.103 ± 0.78
1.103HisVal: 1.103 ± 0.78
0.0HisTrp: 0.0 ± 0.0
2.205HisTyr: 2.205 ± 1.561
0.0HisXaa: 0.0 ± 0.0
Ile
7.718IleAla: 7.718 ± 0.519
1.103IleCys: 1.103 ± 0.78
5.513IleAsp: 5.513 ± 1.042
3.308IleGlu: 3.308 ± 0.693
2.205IlePhe: 2.205 ± 1.561
5.513IleGly: 5.513 ± 0.606
2.205IleHis: 2.205 ± 1.561
5.513IleIle: 5.513 ± 1.042
3.308IleLys: 3.308 ± 0.693
5.513IleLeu: 5.513 ± 0.606
2.205IleMet: 2.205 ± 0.087
2.205IleAsn: 2.205 ± 1.561
3.308IlePro: 3.308 ± 0.693
2.205IleGln: 2.205 ± 1.561
8.82IleArg: 8.82 ± 0.349
3.308IleSer: 3.308 ± 0.955
4.41IleThr: 4.41 ± 1.822
1.103IleVal: 1.103 ± 0.78
0.0IleTrp: 0.0 ± 0.0
5.513IleTyr: 5.513 ± 0.606
0.0IleXaa: 0.0 ± 0.0
Lys
4.41LysAla: 4.41 ± 1.473
0.0LysCys: 0.0 ± 0.0
1.103LysAsp: 1.103 ± 0.78
2.205LysGlu: 2.205 ± 1.561
0.0LysPhe: 0.0 ± 0.0
2.205LysGly: 2.205 ± 1.561
3.308LysHis: 3.308 ± 0.693
2.205LysIle: 2.205 ± 1.561
2.205LysLys: 2.205 ± 0.087
5.513LysLeu: 5.513 ± 1.042
1.103LysMet: 1.103 ± 0.78
0.0LysAsn: 0.0 ± 0.0
2.205LysPro: 2.205 ± 1.735
2.205LysGln: 2.205 ± 1.735
5.513LysArg: 5.513 ± 0.606
2.205LysSer: 2.205 ± 1.735
4.41LysThr: 4.41 ± 1.473
2.205LysVal: 2.205 ± 1.735
0.0LysTrp: 0.0 ± 0.0
1.103LysTyr: 1.103 ± 0.78
0.0LysXaa: 0.0 ± 0.0
Leu
3.308LeuAla: 3.308 ± 2.603
1.103LeuCys: 1.103 ± 0.78
5.513LeuAsp: 5.513 ± 2.254
5.513LeuGlu: 5.513 ± 2.254
4.41LeuPhe: 4.41 ± 1.822
3.308LeuGly: 3.308 ± 0.693
1.103LeuHis: 1.103 ± 0.868
7.718LeuIle: 7.718 ± 2.167
2.205LeuLys: 2.205 ± 1.561
4.41LeuLeu: 4.41 ± 1.473
3.308LeuMet: 3.308 ± 0.955
5.513LeuAsn: 5.513 ± 2.254
2.205LeuPro: 2.205 ± 0.087
2.205LeuGln: 2.205 ± 0.087
6.615LeuArg: 6.615 ± 0.262
3.308LeuSer: 3.308 ± 0.693
4.41LeuThr: 4.41 ± 0.174
3.308LeuVal: 3.308 ± 0.955
1.103LeuTrp: 1.103 ± 0.78
5.513LeuTyr: 5.513 ± 2.254
0.0LeuXaa: 0.0 ± 0.0
Met
3.308MetAla: 3.308 ± 0.693
1.103MetCys: 1.103 ± 0.78
2.205MetAsp: 2.205 ± 0.087
3.308MetGlu: 3.308 ± 2.603
1.103MetPhe: 1.103 ± 0.78
1.103MetGly: 1.103 ± 0.868
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
1.103MetLys: 1.103 ± 0.868
1.103MetLeu: 1.103 ± 0.78
0.0MetMet: 0.0 ± 0.0
1.103MetAsn: 1.103 ± 0.868
0.0MetPro: 0.0 ± 0.0
0.0MetGln: 0.0 ± 0.0
0.0MetArg: 0.0 ± 0.0
0.0MetSer: 0.0 ± 0.0
1.103MetThr: 1.103 ± 0.868
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
1.103MetTyr: 1.103 ± 0.78
0.0MetXaa: 0.0 ± 0.0
Asn
4.41AsnAla: 4.41 ± 3.47
0.0AsnCys: 0.0 ± 0.0
1.103AsnAsp: 1.103 ± 0.78
0.0AsnGlu: 0.0 ± 0.0
2.205AsnPhe: 2.205 ± 0.087
1.103AsnGly: 1.103 ± 0.78
1.103AsnHis: 1.103 ± 0.78
3.308AsnIle: 3.308 ± 0.693
2.205AsnLys: 2.205 ± 0.087
2.205AsnLeu: 2.205 ± 0.087
3.308AsnMet: 3.308 ± 0.955
0.0AsnAsn: 0.0 ± 0.0
5.513AsnPro: 5.513 ± 2.254
1.103AsnGln: 1.103 ± 0.78
1.103AsnArg: 1.103 ± 0.78
1.103AsnSer: 1.103 ± 0.78
1.103AsnThr: 1.103 ± 0.868
2.205AsnVal: 2.205 ± 0.087
1.103AsnTrp: 1.103 ± 0.868
1.103AsnTyr: 1.103 ± 0.868
0.0AsnXaa: 0.0 ± 0.0
Pro
3.308ProAla: 3.308 ± 0.955
1.103ProCys: 1.103 ± 0.868
5.513ProAsp: 5.513 ± 3.902
2.205ProGlu: 2.205 ± 1.561
1.103ProPhe: 1.103 ± 0.868
1.103ProGly: 1.103 ± 0.868
2.205ProHis: 2.205 ± 0.087
3.308ProIle: 3.308 ± 0.693
4.41ProLys: 4.41 ± 1.473
4.41ProLeu: 4.41 ± 0.174
0.0ProMet: 0.0 ± 0.536
3.308ProAsn: 3.308 ± 0.693
3.308ProPro: 3.308 ± 2.603
1.103ProGln: 1.103 ± 0.78
3.308ProArg: 3.308 ± 0.955
5.513ProSer: 5.513 ± 1.042
2.205ProThr: 2.205 ± 1.735
2.205ProVal: 2.205 ± 0.087
1.103ProTrp: 1.103 ± 0.868
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
3.308GlnAla: 3.308 ± 0.955
0.0GlnCys: 0.0 ± 0.0
2.205GlnAsp: 2.205 ± 0.087
0.0GlnGlu: 0.0 ± 0.0
1.103GlnPhe: 1.103 ± 0.78
3.308GlnGly: 3.308 ± 0.693
0.0GlnHis: 0.0 ± 0.0
0.0GlnIle: 0.0 ± 0.0
2.205GlnLys: 2.205 ± 1.735
4.41GlnLeu: 4.41 ± 0.174
1.103GlnMet: 1.103 ± 0.569
2.205GlnAsn: 2.205 ± 1.735
0.0GlnPro: 0.0 ± 0.0
3.308GlnGln: 3.308 ± 2.603
2.205GlnArg: 2.205 ± 1.561
1.103GlnSer: 1.103 ± 0.78
1.103GlnThr: 1.103 ± 0.868
3.308GlnVal: 3.308 ± 0.955
1.103GlnTrp: 1.103 ± 0.868
5.513GlnTyr: 5.513 ± 0.606
0.0GlnXaa: 0.0 ± 0.0
Arg
6.615ArgAla: 6.615 ± 3.034
1.103ArgCys: 1.103 ± 0.78
5.513ArgAsp: 5.513 ± 1.042
3.308ArgGlu: 3.308 ± 0.955
4.41ArgPhe: 4.41 ± 1.822
3.308ArgGly: 3.308 ± 0.693
1.103ArgHis: 1.103 ± 0.78
4.41ArgIle: 4.41 ± 1.822
1.103ArgLys: 1.103 ± 0.78
4.41ArgLeu: 4.41 ± 3.121
2.205ArgMet: 2.205 ± 0.087
2.205ArgAsn: 2.205 ± 1.735
4.41ArgPro: 4.41 ± 3.47
3.308ArgGln: 3.308 ± 0.693
5.513ArgArg: 5.513 ± 1.042
5.513ArgSer: 5.513 ± 1.042
4.41ArgThr: 4.41 ± 0.174
5.513ArgVal: 5.513 ± 0.606
1.103ArgTrp: 1.103 ± 0.868
1.103ArgTyr: 1.103 ± 0.868
0.0ArgXaa: 0.0 ± 0.0
Ser
5.513SerAla: 5.513 ± 0.606
1.103SerCys: 1.103 ± 0.868
1.103SerAsp: 1.103 ± 0.868
5.513SerGlu: 5.513 ± 0.606
1.103SerPhe: 1.103 ± 0.868
4.41SerGly: 4.41 ± 0.174
1.103SerHis: 1.103 ± 0.78
6.615SerIle: 6.615 ± 1.386
3.308SerLys: 3.308 ± 0.955
4.41SerLeu: 4.41 ± 3.121
1.103SerMet: 1.103 ± 0.868
1.103SerAsn: 1.103 ± 0.78
0.0SerPro: 0.0 ± 0.0
3.308SerGln: 3.308 ± 0.955
4.41SerArg: 4.41 ± 1.822
5.513SerSer: 5.513 ± 0.606
4.41SerThr: 4.41 ± 3.47
4.41SerVal: 4.41 ± 1.473
0.0SerTrp: 0.0 ± 0.0
3.308SerTyr: 3.308 ± 0.693
0.0SerXaa: 0.0 ± 0.0
Thr
4.41ThrAla: 4.41 ± 1.822
0.0ThrCys: 0.0 ± 0.0
5.513ThrAsp: 5.513 ± 1.042
3.308ThrGlu: 3.308 ± 0.693
2.205ThrPhe: 2.205 ± 1.561
2.205ThrGly: 2.205 ± 1.735
1.103ThrHis: 1.103 ± 0.868
0.0ThrIle: 0.0 ± 0.0
2.205ThrLys: 2.205 ± 0.087
5.513ThrLeu: 5.513 ± 1.042
1.103ThrMet: 1.103 ± 0.78
2.205ThrAsn: 2.205 ± 1.735
4.41ThrPro: 4.41 ± 3.47
7.718ThrGln: 7.718 ± 2.777
3.308ThrArg: 3.308 ± 0.693
5.513ThrSer: 5.513 ± 1.042
7.718ThrThr: 7.718 ± 4.425
3.308ThrVal: 3.308 ± 2.341
1.103ThrTrp: 1.103 ± 0.868
3.308ThrTyr: 3.308 ± 0.955
0.0ThrXaa: 0.0 ± 0.0
Val
4.41ValAla: 4.41 ± 3.121
0.0ValCys: 0.0 ± 0.0
1.103ValAsp: 1.103 ± 0.78
3.308ValGlu: 3.308 ± 0.955
1.103ValPhe: 1.103 ± 0.78
4.41ValGly: 4.41 ± 0.174
2.205ValHis: 2.205 ± 0.087
2.205ValIle: 2.205 ± 0.087
0.0ValLys: 0.0 ± 0.0
4.41ValLeu: 4.41 ± 1.473
0.0ValMet: 0.0 ± 0.0
2.205ValAsn: 2.205 ± 0.087
6.615ValPro: 6.615 ± 3.034
0.0ValGln: 0.0 ± 0.0
4.41ValArg: 4.41 ± 1.822
7.718ValSer: 7.718 ± 1.129
4.41ValThr: 4.41 ± 1.822
2.205ValVal: 2.205 ± 0.087
1.103ValTrp: 1.103 ± 0.78
0.0ValTyr: 0.0 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
1.103TrpAsp: 1.103 ± 0.868
2.205TrpGlu: 2.205 ± 1.735
2.205TrpPhe: 2.205 ± 1.735
1.103TrpGly: 1.103 ± 0.78
1.103TrpHis: 1.103 ± 0.868
0.0TrpIle: 0.0 ± 0.0
1.103TrpLys: 1.103 ± 0.78
1.103TrpLeu: 1.103 ± 0.868
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
2.205TrpGln: 2.205 ± 1.735
1.103TrpArg: 1.103 ± 0.868
4.41TrpSer: 4.41 ± 3.121
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
4.41TyrAla: 4.41 ± 1.822
1.103TyrCys: 1.103 ± 0.868
1.103TyrAsp: 1.103 ± 0.868
5.513TyrGlu: 5.513 ± 2.254
2.205TyrPhe: 2.205 ± 0.087
5.513TyrGly: 5.513 ± 2.254
3.308TyrHis: 3.308 ± 0.693
4.41TyrIle: 4.41 ± 0.174
1.103TyrLys: 1.103 ± 0.868
2.205TyrLeu: 2.205 ± 0.087
0.0TyrMet: 0.0 ± 0.0
1.103TyrAsn: 1.103 ± 0.78
1.103TyrPro: 1.103 ± 0.78
0.0TyrGln: 0.0 ± 0.0
3.308TyrArg: 3.308 ± 2.341
3.308TyrSer: 3.308 ± 0.955
3.308TyrThr: 3.308 ± 0.693
4.41TyrVal: 4.41 ± 0.174
1.103TyrTrp: 1.103 ± 0.78
3.308TyrTyr: 3.308 ± 0.955
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (908 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski