Amino acid dipepetide frequency for Feline calicivirus (strain Cat/United States/Urbana/1960) (FCV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.886AlaAla: 7.886 ± 2.008
1.577AlaCys: 1.577 ± 0.862
2.366AlaAsp: 2.366 ± 0.961
3.155AlaGlu: 3.155 ± 1.062
2.76AlaPhe: 2.76 ± 0.428
3.155AlaGly: 3.155 ± 1.364
1.577AlaHis: 1.577 ± 0.862
6.309AlaIle: 6.309 ± 0.868
5.126AlaLys: 5.126 ± 0.97
7.492AlaLeu: 7.492 ± 3.699
1.577AlaMet: 1.577 ± 0.862
5.126AlaAsn: 5.126 ± 1.172
1.972AlaPro: 1.972 ± 0.445
1.972AlaGln: 1.972 ± 1.287
3.549AlaArg: 3.549 ± 0.917
4.338AlaSer: 4.338 ± 0.687
5.521AlaThr: 5.521 ± 1.704
3.155AlaVal: 3.155 ± 1.062
1.577AlaTrp: 1.577 ± 1.325
0.789AlaTyr: 0.789 ± 0.431
0.0AlaXaa: 0.0 ± 0.0
Cys
1.577CysAla: 1.577 ± 0.271
0.789CysCys: 0.789 ± 0.32
2.366CysAsp: 2.366 ± 0.408
0.0CysGlu: 0.0 ± 0.0
0.789CysPhe: 0.789 ± 0.431
2.366CysGly: 2.366 ± 0.644
0.394CysHis: 0.394 ± 0.215
1.183CysIle: 1.183 ± 0.204
1.577CysLys: 1.577 ± 0.862
1.183CysLeu: 1.183 ± 0.646
0.394CysMet: 0.394 ± 0.215
0.789CysAsn: 0.789 ± 0.431
1.183CysPro: 1.183 ± 0.646
0.394CysGln: 0.394 ± 0.215
0.0CysArg: 0.0 ± 0.0
0.789CysSer: 0.789 ± 0.32
1.183CysThr: 1.183 ± 0.646
1.183CysVal: 1.183 ± 0.646
0.394CysTrp: 0.394 ± 0.215
1.972CysTyr: 1.972 ± 0.445
0.0CysXaa: 0.0 ± 0.0
Asp
1.972AspAla: 1.972 ± 0.492
0.789AspCys: 0.789 ± 0.32
4.732AspAsp: 4.732 ± 0.743
4.732AspGlu: 4.732 ± 1.289
3.943AspPhe: 3.943 ± 1.602
2.76AspGly: 2.76 ± 0.805
1.183AspHis: 1.183 ± 0.646
2.76AspIle: 2.76 ± 0.805
3.155AspLys: 3.155 ± 1.083
4.338AspLeu: 4.338 ± 0.878
1.972AspMet: 1.972 ± 0.445
1.972AspAsn: 1.972 ± 0.492
3.943AspPro: 3.943 ± 1.512
2.366AspGln: 2.366 ± 1.28
1.577AspArg: 1.577 ± 1.271
5.521AspSer: 5.521 ± 0.857
3.549AspThr: 3.549 ± 1.719
6.309AspVal: 6.309 ± 1.53
0.394AspTrp: 0.394 ± 0.215
1.577AspTyr: 1.577 ± 0.271
0.0AspXaa: 0.0 ± 0.0
Glu
5.915GluAla: 5.915 ± 1.02
1.183GluCys: 1.183 ± 0.646
2.366GluAsp: 2.366 ± 1.293
1.972GluGlu: 1.972 ± 0.445
1.972GluPhe: 1.972 ± 0.492
1.577GluGly: 1.577 ± 0.271
3.155GluHis: 3.155 ± 1.062
1.577GluIle: 1.577 ± 0.862
2.76GluLys: 2.76 ± 0.428
4.732GluLeu: 4.732 ± 2.346
0.0GluMet: 0.0 ± 0.0
1.577GluAsn: 1.577 ± 0.862
2.76GluPro: 2.76 ± 0.428
1.577GluGln: 1.577 ± 2.814
1.183GluArg: 1.183 ± 0.204
2.366GluSer: 2.366 ± 0.644
3.549GluThr: 3.549 ± 1.122
2.366GluVal: 2.366 ± 0.961
1.972GluTrp: 1.972 ± 0.492
1.577GluTyr: 1.577 ± 0.862
0.0GluXaa: 0.0 ± 0.0
Phe
2.366PheAla: 2.366 ± 0.644
0.789PheCys: 0.789 ± 0.32
3.155PheAsp: 3.155 ± 1.282
1.577PheGlu: 1.577 ± 0.862
1.577PhePhe: 1.577 ± 0.271
0.789PheGly: 0.789 ± 1.013
1.577PheHis: 1.577 ± 0.641
1.577PheIle: 1.577 ± 0.641
2.366PheLys: 2.366 ± 2.347
2.76PheLeu: 2.76 ± 0.852
0.394PheMet: 0.394 ± 0.215
2.366PheAsn: 2.366 ± 1.28
1.183PhePro: 1.183 ± 0.204
1.577PheGln: 1.577 ± 1.325
3.155PheArg: 3.155 ± 1.007
3.549PheSer: 3.549 ± 0.612
1.972PheThr: 1.972 ± 0.445
3.549PheVal: 3.549 ± 0.612
0.789PheTrp: 0.789 ± 0.32
2.76PheTyr: 2.76 ± 1.071
0.0PheXaa: 0.0 ± 0.0
Gly
3.549GlyAla: 3.549 ± 0.612
2.76GlyCys: 2.76 ± 0.852
2.76GlyAsp: 2.76 ± 0.805
3.943GlyGlu: 3.943 ± 0.614
3.155GlyPhe: 3.155 ± 1.007
3.943GlyGly: 3.943 ± 0.614
1.183GlyHis: 1.183 ± 0.646
3.549GlyIle: 3.549 ± 1.122
6.309GlyLys: 6.309 ± 0.868
5.126GlyLeu: 5.126 ± 2.31
1.972GlyMet: 1.972 ± 0.445
2.366GlyAsn: 2.366 ± 1.64
3.549GlyPro: 3.549 ± 1.138
1.577GlyGln: 1.577 ± 1.271
1.972GlyArg: 1.972 ± 1.077
6.703GlySer: 6.703 ± 3.055
2.366GlyThr: 2.366 ± 0.408
7.886GlyVal: 7.886 ± 1.479
1.183GlyTrp: 1.183 ± 0.82
1.577GlyTyr: 1.577 ± 0.641
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.789HisCys: 0.789 ± 0.431
1.183HisAsp: 1.183 ± 0.646
1.577HisGlu: 1.577 ± 0.862
1.183HisPhe: 1.183 ± 0.82
1.183HisGly: 1.183 ± 0.204
0.789HisHis: 0.789 ± 0.32
1.183HisIle: 1.183 ± 0.204
1.577HisLys: 1.577 ± 0.862
3.155HisLeu: 3.155 ± 0.682
0.789HisMet: 0.789 ± 0.431
1.183HisAsn: 1.183 ± 0.646
1.972HisPro: 1.972 ± 0.492
1.972HisGln: 1.972 ± 1.077
1.183HisArg: 1.183 ± 0.646
1.577HisSer: 1.577 ± 0.862
1.972HisThr: 1.972 ± 0.492
2.76HisVal: 2.76 ± 0.428
1.183HisTrp: 1.183 ± 0.204
0.789HisTyr: 0.789 ± 0.32
0.0HisXaa: 0.0 ± 0.0
Ile
1.972IleAla: 1.972 ± 0.492
0.789IleCys: 0.789 ± 0.32
7.492IleAsp: 7.492 ± 0.321
1.183IleGlu: 1.183 ± 1.291
3.155IlePhe: 3.155 ± 1.282
6.309IleGly: 6.309 ± 1.508
0.394IleHis: 0.394 ± 0.215
4.338IleIle: 4.338 ± 0.687
3.943IleLys: 3.943 ± 1.488
5.915IleLeu: 5.915 ± 2.016
1.577IleMet: 1.577 ± 0.271
1.972IleAsn: 1.972 ± 0.492
3.155IlePro: 3.155 ± 1.282
0.789IleGln: 0.789 ± 1.013
6.309IleArg: 6.309 ± 0.868
2.76IleSer: 2.76 ± 1.456
5.915IleThr: 5.915 ± 1.476
4.338IleVal: 4.338 ± 0.687
1.183IleTrp: 1.183 ± 0.646
0.789IleTyr: 0.789 ± 0.32
0.0IleXaa: 0.0 ± 0.0
Lys
4.338LysAla: 4.338 ± 2.341
0.0LysCys: 0.0 ± 0.0
1.577LysAsp: 1.577 ± 0.862
0.789LysGlu: 0.789 ± 0.431
2.366LysPhe: 2.366 ± 0.408
4.732LysGly: 4.732 ± 1.915
0.394LysHis: 0.394 ± 0.215
6.703LysIle: 6.703 ± 0.666
2.366LysLys: 2.366 ± 0.644
7.492LysLeu: 7.492 ± 2.1
0.394LysMet: 0.394 ± 0.215
2.366LysAsn: 2.366 ± 1.28
5.126LysPro: 5.126 ± 1.495
1.577LysGln: 1.577 ± 0.271
2.76LysArg: 2.76 ± 1.508
4.338LysSer: 4.338 ± 1.701
3.549LysThr: 3.549 ± 1.275
3.155LysVal: 3.155 ± 1.724
0.789LysTrp: 0.789 ± 0.431
1.972LysTyr: 1.972 ± 0.445
0.0LysXaa: 0.0 ± 0.0
Leu
7.886LeuAla: 7.886 ± 1.744
0.789LeuCys: 0.789 ± 0.431
4.338LeuAsp: 4.338 ± 2.618
5.521LeuGlu: 5.521 ± 0.742
3.155LeuPhe: 3.155 ± 1.364
5.915LeuGly: 5.915 ± 2.454
3.943LeuHis: 3.943 ± 1.488
4.338LeuIle: 4.338 ± 0.86
4.338LeuLys: 4.338 ± 1.086
5.915LeuLeu: 5.915 ± 1.02
2.76LeuMet: 2.76 ± 1.318
5.126LeuAsn: 5.126 ± 2.161
4.732LeuPro: 4.732 ± 0.816
3.943LeuGln: 3.943 ± 2.533
3.943LeuArg: 3.943 ± 1.488
7.886LeuSer: 7.886 ± 1.547
5.126LeuThr: 5.126 ± 1.495
3.155LeuVal: 3.155 ± 0.682
0.789LeuTrp: 0.789 ± 0.32
2.366LeuTyr: 2.366 ± 0.408
0.0LeuXaa: 0.0 ± 0.0
Met
1.577MetAla: 1.577 ± 0.271
1.183MetCys: 1.183 ± 0.82
0.789MetAsp: 0.789 ± 0.431
0.394MetGlu: 0.394 ± 0.215
1.183MetPhe: 1.183 ± 0.646
1.577MetGly: 1.577 ± 0.271
0.789MetHis: 0.789 ± 1.013
0.789MetIle: 0.789 ± 0.431
0.789MetLys: 0.789 ± 0.431
3.155MetLeu: 3.155 ± 0.542
0.789MetMet: 0.789 ± 0.431
0.789MetAsn: 0.789 ± 2.861
0.789MetPro: 0.789 ± 0.431
0.394MetGln: 0.394 ± 0.215
0.0MetArg: 0.0 ± 0.0
1.972MetSer: 1.972 ± 0.492
2.366MetThr: 2.366 ± 0.644
1.183MetVal: 1.183 ± 0.204
0.0MetTrp: 0.0 ± 0.0
0.789MetTyr: 0.789 ± 0.32
0.0MetXaa: 0.0 ± 0.0
Asn
2.366AsnAla: 2.366 ± 1.339
1.183AsnCys: 1.183 ± 0.646
1.972AsnAsp: 1.972 ± 1.831
1.577AsnGlu: 1.577 ± 0.271
1.577AsnPhe: 1.577 ± 1.273
4.338AsnGly: 4.338 ± 0.687
2.76AsnHis: 2.76 ± 0.805
1.577AsnIle: 1.577 ± 0.271
2.366AsnLys: 2.366 ± 1.101
3.155AsnLeu: 3.155 ± 2.443
0.789AsnMet: 0.789 ± 0.875
1.972AsnAsn: 1.972 ± 1.17
3.943AsnPro: 3.943 ± 0.984
2.366AsnGln: 2.366 ± 2.803
1.183AsnArg: 1.183 ± 1.52
4.732AsnSer: 4.732 ± 0.743
2.76AsnThr: 2.76 ± 1.131
1.972AsnVal: 1.972 ± 0.492
0.789AsnTrp: 0.789 ± 1.013
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
2.366ProAla: 2.366 ± 0.644
0.0ProCys: 0.0 ± 0.0
3.943ProAsp: 3.943 ± 0.984
1.972ProGlu: 1.972 ± 1.831
1.183ProPhe: 1.183 ± 0.204
4.338ProGly: 4.338 ± 1.441
1.972ProHis: 1.972 ± 1.137
3.549ProIle: 3.549 ± 0.612
3.549ProLys: 3.549 ± 1.275
5.126ProLeu: 5.126 ± 1.496
1.577ProMet: 1.577 ± 0.271
1.972ProAsn: 1.972 ± 0.492
4.338ProPro: 4.338 ± 0.878
0.789ProGln: 0.789 ± 0.431
1.577ProArg: 1.577 ± 0.271
4.338ProSer: 4.338 ± 0.687
2.76ProThr: 2.76 ± 1.508
3.943ProVal: 3.943 ± 0.89
0.789ProTrp: 0.789 ± 0.431
3.549ProTyr: 3.549 ± 0.917
0.0ProXaa: 0.0 ± 0.0
Gln
1.183GlnAla: 1.183 ± 1.402
0.0GlnCys: 0.0 ± 0.0
1.183GlnAsp: 1.183 ± 0.82
0.789GlnGlu: 0.789 ± 0.32
1.972GlnPhe: 1.972 ± 1.287
2.366GlnGly: 2.366 ± 1.28
1.183GlnHis: 1.183 ± 0.646
3.155GlnIle: 3.155 ± 1.007
2.366GlnLys: 2.366 ± 1.293
2.366GlnLeu: 2.366 ± 1.28
0.394GlnMet: 0.394 ± 0.507
0.394GlnAsn: 0.394 ± 1.43
0.789GlnPro: 0.789 ± 0.32
1.577GlnGln: 1.577 ± 2.69
2.76GlnArg: 2.76 ± 4.029
3.943GlnSer: 3.943 ± 1.01
1.972GlnThr: 1.972 ± 0.492
1.183GlnVal: 1.183 ± 1.402
0.0GlnTrp: 0.0 ± 0.0
1.577GlnTyr: 1.577 ± 0.641
0.0GlnXaa: 0.0 ± 0.0
Arg
3.549ArgAla: 3.549 ± 1.138
0.789ArgCys: 0.789 ± 0.431
1.183ArgAsp: 1.183 ± 0.646
2.366ArgGlu: 2.366 ± 1.101
1.972ArgPhe: 1.972 ± 1.137
3.549ArgGly: 3.549 ± 1.275
1.577ArgHis: 1.577 ± 0.271
2.76ArgIle: 2.76 ± 0.428
1.972ArgLys: 1.972 ± 1.077
5.126ArgLeu: 5.126 ± 2.161
0.789ArgMet: 0.789 ± 1.345
1.183ArgAsn: 1.183 ± 1.402
2.76ArgPro: 2.76 ± 0.428
1.577ArgGln: 1.577 ± 1.623
2.76ArgArg: 2.76 ± 1.508
5.126ArgSer: 5.126 ± 0.97
2.366ArgThr: 2.366 ± 1.293
3.155ArgVal: 3.155 ± 2.443
0.0ArgTrp: 0.0 ± 0.0
0.789ArgTyr: 0.789 ± 0.431
0.0ArgXaa: 0.0 ± 0.0
Ser
5.521SerAla: 5.521 ± 3.016
1.972SerCys: 1.972 ± 1.077
6.309SerAsp: 6.309 ± 1.364
5.126SerGlu: 5.126 ± 0.97
3.155SerPhe: 3.155 ± 0.682
6.703SerGly: 6.703 ± 1.278
1.577SerHis: 1.577 ± 0.862
6.703SerIle: 6.703 ± 1.293
2.76SerLys: 2.76 ± 0.852
6.309SerLeu: 6.309 ± 1.007
1.183SerMet: 1.183 ± 0.82
2.366SerAsn: 2.366 ± 2.337
2.76SerPro: 2.76 ± 0.852
1.972SerGln: 1.972 ± 0.492
3.943SerArg: 3.943 ± 1.488
5.521SerSer: 5.521 ± 0.857
7.492SerThr: 7.492 ± 2.72
7.886SerVal: 7.886 ± 0.854
1.183SerTrp: 1.183 ± 0.204
3.155SerTyr: 3.155 ± 2.443
0.0SerXaa: 0.0 ± 0.0
Thr
7.098ThrAla: 7.098 ± 1.663
0.394ThrCys: 0.394 ± 0.507
2.366ThrAsp: 2.366 ± 0.961
1.577ThrGlu: 1.577 ± 0.862
1.183ThrPhe: 1.183 ± 0.646
3.943ThrGly: 3.943 ± 0.89
1.577ThrHis: 1.577 ± 0.271
3.549ThrIle: 3.549 ± 1.181
4.338ThrLys: 4.338 ± 0.687
6.703ThrLeu: 6.703 ± 1.73
1.183ThrMet: 1.183 ± 0.204
2.76ThrAsn: 2.76 ± 2.669
3.155ThrPro: 3.155 ± 1.062
2.366ThrGln: 2.366 ± 0.644
2.366ThrArg: 2.366 ± 1.293
9.858ThrSer: 9.858 ± 1.54
4.338ThrThr: 4.338 ± 0.878
5.126ThrVal: 5.126 ± 1.496
0.789ThrTrp: 0.789 ± 0.431
1.972ThrTyr: 1.972 ± 0.445
0.0ThrXaa: 0.0 ± 0.0
Val
6.309ValAla: 6.309 ± 1.53
3.155ValCys: 3.155 ± 1.724
4.732ValAsp: 4.732 ± 0.938
5.521ValGlu: 5.521 ± 0.742
2.366ValPhe: 2.366 ± 0.961
4.732ValGly: 4.732 ± 1.295
1.183ValHis: 1.183 ± 0.646
6.309ValIle: 6.309 ± 1.927
1.972ValLys: 1.972 ± 1.077
3.549ValLeu: 3.549 ± 0.612
0.789ValMet: 0.789 ± 0.39
2.76ValAsn: 2.76 ± 0.852
4.338ValPro: 4.338 ± 1.441
2.366ValGln: 2.366 ± 1.28
2.76ValArg: 2.76 ± 1.131
3.943ValSer: 3.943 ± 1.488
5.915ValThr: 5.915 ± 1.324
3.943ValVal: 3.943 ± 0.984
0.789ValTrp: 0.789 ± 0.32
1.972ValTyr: 1.972 ± 0.492
0.0ValXaa: 0.0 ± 0.0
Trp
0.789TrpAla: 0.789 ± 0.431
0.394TrpCys: 0.394 ± 0.215
1.577TrpAsp: 1.577 ± 1.325
0.789TrpGlu: 0.789 ± 0.32
0.789TrpPhe: 0.789 ± 0.32
1.183TrpGly: 1.183 ± 0.204
0.0TrpHis: 0.0 ± 0.0
0.394TrpIle: 0.394 ± 0.507
1.577TrpLys: 1.577 ± 0.862
0.0TrpLeu: 0.0 ± 0.0
0.394TrpMet: 0.394 ± 0.215
1.972TrpAsn: 1.972 ± 0.445
0.394TrpPro: 0.394 ± 0.507
0.0TrpGln: 0.0 ± 0.0
0.789TrpArg: 0.789 ± 0.431
2.76TrpSer: 2.76 ± 2.144
0.0TrpThr: 0.0 ± 0.0
0.394TrpVal: 0.394 ± 0.215
0.394TrpTrp: 0.394 ± 0.215
0.394TrpTyr: 0.394 ± 0.215
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.76TyrAla: 2.76 ± 0.428
1.183TyrCys: 1.183 ± 0.646
3.155TyrAsp: 3.155 ± 1.083
1.577TyrGlu: 1.577 ± 0.271
0.394TyrPhe: 0.394 ± 0.215
1.972TyrGly: 1.972 ± 1.077
0.789TyrHis: 0.789 ± 0.32
1.972TyrIle: 1.972 ± 0.445
1.577TyrLys: 1.577 ± 0.271
2.366TyrLeu: 2.366 ± 0.961
1.183TyrMet: 1.183 ± 0.204
2.76TyrAsn: 2.76 ± 0.428
0.789TyrPro: 0.789 ± 1.013
0.0TyrGln: 0.0 ± 0.0
1.577TyrArg: 1.577 ± 1.273
1.577TyrSer: 1.577 ± 1.271
1.972TyrThr: 1.972 ± 1.17
2.76TyrVal: 2.76 ± 0.428
0.0TyrTrp: 0.0 ± 0.0
0.789TyrTyr: 0.789 ± 0.32
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (2537 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski