Amino acid dipepetide frequency for African eggplant yellowing virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.884AlaAla: 4.884 ± 1.18
1.303AlaCys: 1.303 ± 0.668
3.908AlaAsp: 3.908 ± 0.858
5.861AlaGlu: 5.861 ± 0.964
3.256AlaPhe: 3.256 ± 0.597
8.141AlaGly: 8.141 ± 1.291
0.977AlaHis: 0.977 ± 0.638
2.279AlaIle: 2.279 ± 0.907
5.21AlaLys: 5.21 ± 1.584
7.489AlaLeu: 7.489 ± 1.229
1.628AlaMet: 1.628 ± 0.575
1.628AlaAsn: 1.628 ± 1.134
4.884AlaPro: 4.884 ± 0.911
3.256AlaGln: 3.256 ± 1.157
3.908AlaArg: 3.908 ± 0.758
6.513AlaSer: 6.513 ± 2.151
4.559AlaThr: 4.559 ± 1.512
2.931AlaVal: 2.931 ± 0.875
0.326AlaTrp: 0.326 ± 0.279
2.605AlaTyr: 2.605 ± 0.713
0.0AlaXaa: 0.0 ± 0.0
Cys
0.651CysAla: 0.651 ± 0.356
0.0CysCys: 0.0 ± 0.0
0.326CysAsp: 0.326 ± 0.213
0.651CysGlu: 0.651 ± 0.289
0.0CysPhe: 0.0 ± 0.0
1.303CysGly: 1.303 ± 0.712
0.0CysHis: 0.0 ± 0.0
1.303CysIle: 1.303 ± 1.014
1.303CysLys: 1.303 ± 0.343
3.256CysLeu: 3.256 ± 0.748
0.0CysMet: 0.0 ± 0.0
0.977CysAsn: 0.977 ± 0.399
0.0CysPro: 0.0 ± 0.0
0.651CysGln: 0.651 ± 0.495
0.651CysArg: 0.651 ± 0.356
0.651CysSer: 0.651 ± 0.426
0.651CysThr: 0.651 ± 0.426
0.977CysVal: 0.977 ± 0.202
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.256AspAla: 3.256 ± 0.427
0.326AspCys: 0.326 ± 0.213
6.513AspAsp: 6.513 ± 0.361
2.279AspGlu: 2.279 ± 0.619
2.605AspPhe: 2.605 ± 0.294
2.931AspGly: 2.931 ± 0.62
1.954AspHis: 1.954 ± 0.404
0.977AspIle: 0.977 ± 0.202
0.326AspLys: 0.326 ± 0.279
3.908AspLeu: 3.908 ± 0.596
0.326AspMet: 0.326 ± 0.213
1.628AspAsn: 1.628 ± 0.985
2.279AspPro: 2.279 ± 0.801
1.954AspGln: 1.954 ± 0.767
3.582AspArg: 3.582 ± 1.708
3.582AspSer: 3.582 ± 0.416
1.954AspThr: 1.954 ± 0.723
3.256AspVal: 3.256 ± 1.033
0.326AspTrp: 0.326 ± 0.213
0.651AspTyr: 0.651 ± 0.289
0.0AspXaa: 0.0 ± 0.0
Glu
3.582GluAla: 3.582 ± 0.862
0.0GluCys: 0.0 ± 0.0
4.233GluAsp: 4.233 ± 1.016
4.559GluGlu: 4.559 ± 0.903
1.628GluPhe: 1.628 ± 0.542
4.233GluGly: 4.233 ± 1.075
0.977GluHis: 0.977 ± 0.399
1.303GluIle: 1.303 ± 0.587
5.536GluLys: 5.536 ± 1.408
4.233GluLeu: 4.233 ± 0.477
0.326GluMet: 0.326 ± 0.313
3.256GluAsn: 3.256 ± 0.548
2.279GluPro: 2.279 ± 0.684
1.628GluGln: 1.628 ± 0.322
2.931GluArg: 2.931 ± 0.691
4.884GluSer: 4.884 ± 0.883
4.233GluThr: 4.233 ± 0.252
5.861GluVal: 5.861 ± 1.377
2.931GluTrp: 2.931 ± 0.667
0.977GluTyr: 0.977 ± 0.707
0.0GluXaa: 0.0 ± 0.0
Phe
3.582PheAla: 3.582 ± 1.25
0.651PheCys: 0.651 ± 0.356
1.303PheAsp: 1.303 ± 0.54
2.931PheGlu: 2.931 ± 0.908
1.954PhePhe: 1.954 ± 0.385
3.908PheGly: 3.908 ± 0.413
0.0PheHis: 0.0 ± 0.0
1.628PheIle: 1.628 ± 0.57
1.303PheLys: 1.303 ± 0.431
3.256PheLeu: 3.256 ± 1.094
0.977PheMet: 0.977 ± 0.202
1.628PheAsn: 1.628 ± 0.493
2.605PhePro: 2.605 ± 0.668
0.651PheGln: 0.651 ± 0.376
2.931PheArg: 2.931 ± 0.975
4.559PheSer: 4.559 ± 1.186
3.582PheThr: 3.582 ± 0.567
3.908PheVal: 3.908 ± 0.617
0.0PheTrp: 0.0 ± 0.0
1.303PheTyr: 1.303 ± 0.578
0.0PheXaa: 0.0 ± 0.0
Gly
3.908GlyAla: 3.908 ± 0.517
1.954GlyCys: 1.954 ± 0.721
3.256GlyAsp: 3.256 ± 1.062
3.256GlyGlu: 3.256 ± 0.748
4.559GlyPhe: 4.559 ± 0.818
7.489GlyGly: 7.489 ± 3.458
1.954GlyHis: 1.954 ± 1.086
0.977GlyIle: 0.977 ± 0.674
3.582GlyLys: 3.582 ± 0.882
3.582GlyLeu: 3.582 ± 0.759
0.326GlyMet: 0.326 ± 0.259
4.559GlyAsn: 4.559 ± 0.678
3.582GlyPro: 3.582 ± 1.013
1.303GlyGln: 1.303 ± 0.546
6.513GlyArg: 6.513 ± 0.992
8.466GlySer: 8.466 ± 2.559
5.536GlyThr: 5.536 ± 0.66
5.536GlyVal: 5.536 ± 1.434
1.628GlyTrp: 1.628 ± 0.436
1.954GlyTyr: 1.954 ± 0.48
0.0GlyXaa: 0.0 ± 0.0
His
2.931HisAla: 2.931 ± 0.871
0.977HisCys: 0.977 ± 0.626
2.279HisAsp: 2.279 ± 0.44
0.977HisGlu: 0.977 ± 0.626
1.303HisPhe: 1.303 ± 0.265
1.954HisGly: 1.954 ± 0.334
0.326HisHis: 0.326 ± 0.351
0.977HisIle: 0.977 ± 0.512
0.651HisLys: 0.651 ± 0.289
1.628HisLeu: 1.628 ± 0.57
0.326HisMet: 0.326 ± 0.298
0.977HisAsn: 0.977 ± 0.707
1.628HisPro: 1.628 ± 0.661
0.326HisGln: 0.326 ± 0.279
0.651HisArg: 0.651 ± 0.426
0.651HisSer: 0.651 ± 0.356
0.326HisThr: 0.326 ± 0.279
0.651HisVal: 0.651 ± 0.289
0.651HisTrp: 0.651 ± 0.289
0.977HisTyr: 0.977 ± 0.629
0.0HisXaa: 0.0 ± 0.0
Ile
6.513IleAla: 6.513 ± 0.776
0.0IleCys: 0.0 ± 0.0
1.954IleAsp: 1.954 ± 0.66
1.954IleGlu: 1.954 ± 0.654
1.954IlePhe: 1.954 ± 0.369
1.628IleGly: 1.628 ± 0.66
0.326IleHis: 0.326 ± 0.279
1.628IleIle: 1.628 ± 0.44
1.954IleLys: 1.954 ± 1.414
3.582IleLeu: 3.582 ± 1.231
0.977IleMet: 0.977 ± 0.389
2.279IleAsn: 2.279 ± 0.638
5.21IlePro: 5.21 ± 0.937
1.954IleGln: 1.954 ± 0.48
3.256IleArg: 3.256 ± 1.071
2.931IleSer: 2.931 ± 0.385
0.977IleThr: 0.977 ± 0.626
0.977IleVal: 0.977 ± 0.202
1.303IleTrp: 1.303 ± 0.578
0.651IleTyr: 0.651 ± 0.356
0.0IleXaa: 0.0 ± 0.0
Lys
4.884LysAla: 4.884 ± 0.611
0.0LysCys: 0.0 ± 0.0
2.279LysAsp: 2.279 ± 0.734
1.954LysGlu: 1.954 ± 0.484
2.279LysPhe: 2.279 ± 0.868
4.233LysGly: 4.233 ± 0.869
0.977LysHis: 0.977 ± 0.202
3.582LysIle: 3.582 ± 0.551
1.954LysLys: 1.954 ± 0.959
5.861LysLeu: 5.861 ± 0.805
2.279LysMet: 2.279 ± 0.849
1.628LysAsn: 1.628 ± 0.481
4.233LysPro: 4.233 ± 1.046
2.605LysGln: 2.605 ± 0.747
4.233LysArg: 4.233 ± 0.551
4.884LysSer: 4.884 ± 1.094
5.536LysThr: 5.536 ± 0.987
1.303LysVal: 1.303 ± 0.265
0.326LysTrp: 0.326 ± 0.369
0.977LysTyr: 0.977 ± 0.399
0.326LysXaa: 0.326 ± 0.279
Leu
7.489LeuAla: 7.489 ± 1.738
1.954LeuCys: 1.954 ± 0.721
4.233LeuAsp: 4.233 ± 0.511
5.861LeuGlu: 5.861 ± 1.638
6.513LeuPhe: 6.513 ± 2.241
5.536LeuGly: 5.536 ± 1.332
1.954LeuHis: 1.954 ± 0.991
3.582LeuIle: 3.582 ± 0.862
3.256LeuLys: 3.256 ± 0.986
10.094LeuLeu: 10.094 ± 2.429
2.605LeuMet: 2.605 ± 1.147
2.605LeuAsn: 2.605 ± 0.889
4.559LeuPro: 4.559 ± 0.471
3.256LeuGln: 3.256 ± 0.731
7.164LeuArg: 7.164 ± 0.576
7.164LeuSer: 7.164 ± 1.053
4.233LeuThr: 4.233 ± 1.164
2.931LeuVal: 2.931 ± 1.255
1.628LeuTrp: 1.628 ± 0.322
3.256LeuTyr: 3.256 ± 0.888
0.0LeuXaa: 0.0 ± 0.0
Met
1.628MetAla: 1.628 ± 0.413
0.326MetCys: 0.326 ± 0.279
0.0MetAsp: 0.0 ± 0.0
0.326MetGlu: 0.326 ± 0.279
0.977MetPhe: 0.977 ± 0.564
0.651MetGly: 0.651 ± 0.426
0.0MetHis: 0.0 ± 0.0
0.651MetIle: 0.651 ± 0.289
0.651MetLys: 0.651 ± 0.32
1.628MetLeu: 1.628 ± 0.763
0.0MetMet: 0.0 ± 0.0
0.651MetAsn: 0.651 ± 0.504
0.651MetPro: 0.651 ± 0.289
0.651MetGln: 0.651 ± 0.426
1.303MetArg: 1.303 ± 0.578
2.279MetSer: 2.279 ± 0.993
0.651MetThr: 0.651 ± 0.289
3.908MetVal: 3.908 ± 0.77
0.651MetTrp: 0.651 ± 0.289
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
0.326AsnAla: 0.326 ± 0.279
0.977AsnCys: 0.977 ± 0.202
0.0AsnAsp: 0.0 ± 0.0
2.931AsnGlu: 2.931 ± 0.86
0.977AsnPhe: 0.977 ± 0.674
3.256AsnGly: 3.256 ± 0.877
0.977AsnHis: 0.977 ± 0.574
0.977AsnIle: 0.977 ± 0.707
3.582AsnLys: 3.582 ± 0.92
3.582AsnLeu: 3.582 ± 0.609
0.0AsnMet: 0.0 ± 0.0
0.651AsnAsn: 0.651 ± 0.444
2.279AsnPro: 2.279 ± 0.942
0.651AsnGln: 0.651 ± 0.426
1.954AsnArg: 1.954 ± 1.109
5.861AsnSer: 5.861 ± 0.492
2.605AsnThr: 2.605 ± 0.892
2.605AsnVal: 2.605 ± 0.866
1.303AsnTrp: 1.303 ± 0.578
2.605AsnTyr: 2.605 ± 0.892
0.0AsnXaa: 0.0 ± 0.0
Pro
2.931ProAla: 2.931 ± 1.237
0.0ProCys: 0.0 ± 0.0
2.279ProAsp: 2.279 ± 0.619
4.233ProGlu: 4.233 ± 0.507
0.326ProPhe: 0.326 ± 0.351
4.884ProGly: 4.884 ± 1.106
1.628ProHis: 1.628 ± 0.493
2.931ProIle: 2.931 ± 0.978
4.233ProLys: 4.233 ± 1.343
5.21ProLeu: 5.21 ± 1.119
0.977ProMet: 0.977 ± 0.202
1.628ProAsn: 1.628 ± 0.493
5.536ProPro: 5.536 ± 1.279
3.582ProGln: 3.582 ± 0.736
5.536ProArg: 5.536 ± 0.815
5.536ProSer: 5.536 ± 1.052
2.931ProThr: 2.931 ± 0.729
7.489ProVal: 7.489 ± 0.89
0.326ProTrp: 0.326 ± 0.279
0.651ProTyr: 0.651 ± 0.276
0.0ProXaa: 0.0 ± 0.0
Gln
1.954GlnAla: 1.954 ± 0.771
0.0GlnCys: 0.0 ± 0.0
0.651GlnAsp: 0.651 ± 0.557
2.279GlnGlu: 2.279 ± 0.684
2.931GlnPhe: 2.931 ± 0.786
0.977GlnGly: 0.977 ± 0.399
1.303GlnHis: 1.303 ± 0.571
1.954GlnIle: 1.954 ± 0.991
2.931GlnLys: 2.931 ± 0.528
2.931GlnLeu: 2.931 ± 0.69
0.651GlnMet: 0.651 ± 0.504
1.628GlnAsn: 1.628 ± 0.663
1.954GlnPro: 1.954 ± 0.532
2.279GlnGln: 2.279 ± 0.391
2.931GlnArg: 2.931 ± 1.077
3.582GlnSer: 3.582 ± 0.444
0.651GlnThr: 0.651 ± 0.426
1.303GlnVal: 1.303 ± 0.265
1.303GlnTrp: 1.303 ± 0.476
0.977GlnTyr: 0.977 ± 0.436
0.0GlnXaa: 0.0 ± 0.0
Arg
6.513ArgAla: 6.513 ± 0.509
1.303ArgCys: 1.303 ± 0.637
3.582ArgAsp: 3.582 ± 0.587
2.931ArgGlu: 2.931 ± 0.985
1.954ArgPhe: 1.954 ± 0.813
4.233ArgGly: 4.233 ± 1.496
2.279ArgHis: 2.279 ± 0.378
3.908ArgIle: 3.908 ± 0.967
4.884ArgLys: 4.884 ± 1.046
6.513ArgLeu: 6.513 ± 1.469
0.326ArgMet: 0.326 ± 0.279
3.582ArgAsn: 3.582 ± 0.677
3.256ArgPro: 3.256 ± 0.496
1.954ArgGln: 1.954 ± 0.897
8.141ArgArg: 8.141 ± 5.612
4.884ArgSer: 4.884 ± 1.175
1.628ArgThr: 1.628 ± 0.985
3.256ArgVal: 3.256 ± 0.998
0.977ArgTrp: 0.977 ± 0.371
2.279ArgTyr: 2.279 ± 0.56
0.0ArgXaa: 0.0 ± 0.0
Ser
4.233SerAla: 4.233 ± 0.48
1.303SerCys: 1.303 ± 0.571
2.931SerAsp: 2.931 ± 0.731
5.21SerGlu: 5.21 ± 1.453
1.303SerPhe: 1.303 ± 0.28
9.769SerGly: 9.769 ± 1.146
2.605SerHis: 2.605 ± 0.384
5.536SerIle: 5.536 ± 2.484
4.884SerLys: 4.884 ± 1.992
8.466SerLeu: 8.466 ± 0.621
0.0SerMet: 0.0 ± 0.0
3.582SerAsn: 3.582 ± 0.715
4.884SerPro: 4.884 ± 1.271
2.605SerGln: 2.605 ± 1.147
2.605SerArg: 2.605 ± 0.703
9.118SerSer: 9.118 ± 2.392
7.489SerThr: 7.489 ± 1.407
9.118SerVal: 9.118 ± 3.539
2.279SerTrp: 2.279 ± 0.411
1.628SerTyr: 1.628 ± 0.552
0.0SerXaa: 0.0 ± 0.0
Thr
6.513ThrAla: 6.513 ± 0.883
0.651ThrCys: 0.651 ± 0.289
1.303ThrAsp: 1.303 ± 0.552
2.279ThrGlu: 2.279 ± 0.986
4.559ThrPhe: 4.559 ± 0.67
2.605ThrGly: 2.605 ± 0.983
0.326ThrHis: 0.326 ± 0.213
2.931ThrIle: 2.931 ± 1.515
3.582ThrLys: 3.582 ± 0.416
6.513ThrLeu: 6.513 ± 0.866
2.279ThrMet: 2.279 ± 0.456
1.628ThrAsn: 1.628 ± 0.57
5.536ThrPro: 5.536 ± 1.705
0.651ThrGln: 0.651 ± 0.626
4.233ThrArg: 4.233 ± 0.855
3.256ThrSer: 3.256 ± 0.737
3.908ThrThr: 3.908 ± 1.114
3.582ThrVal: 3.582 ± 1.209
0.326ThrTrp: 0.326 ± 0.213
0.977ThrTyr: 0.977 ± 0.574
0.0ThrXaa: 0.0 ± 0.0
Val
5.21ValAla: 5.21 ± 0.251
1.303ValCys: 1.303 ± 0.592
2.279ValAsp: 2.279 ± 0.775
5.21ValGlu: 5.21 ± 1.233
1.303ValPhe: 1.303 ± 0.547
4.233ValGly: 4.233 ± 0.884
0.977ValHis: 0.977 ± 0.375
2.279ValIle: 2.279 ± 0.42
4.233ValLys: 4.233 ± 1.798
5.861ValLeu: 5.861 ± 1.253
0.651ValMet: 0.651 ± 0.333
2.605ValAsn: 2.605 ± 0.922
5.536ValPro: 5.536 ± 0.987
3.256ValGln: 3.256 ± 1.32
2.605ValArg: 2.605 ± 0.886
8.141ValSer: 8.141 ± 0.884
4.559ValThr: 4.559 ± 0.47
4.233ValVal: 4.233 ± 1.378
0.977ValTrp: 0.977 ± 0.375
2.279ValTyr: 2.279 ± 0.485
0.0ValXaa: 0.0 ± 0.0
Trp
2.931TrpAla: 2.931 ± 0.475
0.0TrpCys: 0.0 ± 0.0
0.651TrpAsp: 0.651 ± 0.557
1.954TrpGlu: 1.954 ± 0.798
1.303TrpPhe: 1.303 ± 0.392
0.326TrpGly: 0.326 ± 0.213
0.651TrpHis: 0.651 ± 0.504
0.977TrpIle: 0.977 ± 0.436
0.326TrpLys: 0.326 ± 0.279
1.303TrpLeu: 1.303 ± 0.651
1.628TrpMet: 1.628 ± 0.663
0.326TrpAsn: 0.326 ± 0.351
1.303TrpPro: 1.303 ± 0.265
0.651TrpGln: 0.651 ± 0.424
0.326TrpArg: 0.326 ± 0.213
1.628TrpSer: 1.628 ± 0.594
0.977TrpThr: 0.977 ± 0.202
0.977TrpVal: 0.977 ± 0.399
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.628TyrAla: 1.628 ± 0.439
0.326TyrCys: 0.326 ± 0.351
0.651TyrAsp: 0.651 ± 0.289
1.954TyrGlu: 1.954 ± 0.416
0.977TyrPhe: 0.977 ± 0.399
1.628TyrGly: 1.628 ± 0.552
0.977TyrHis: 0.977 ± 0.448
1.628TyrIle: 1.628 ± 0.552
2.279TyrLys: 2.279 ± 0.683
0.977TyrLeu: 0.977 ± 0.399
0.977TyrMet: 0.977 ± 0.202
0.651TyrAsn: 0.651 ± 0.426
0.651TyrPro: 0.651 ± 0.424
1.303TyrGln: 1.303 ± 0.666
2.931TyrArg: 2.931 ± 0.247
0.977TyrSer: 0.977 ± 0.616
0.651TyrThr: 0.651 ± 0.557
2.605TyrVal: 2.605 ± 0.695
0.977TyrTrp: 0.977 ± 0.202
0.651TyrTyr: 0.651 ± 0.276
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.326XaaVal: 0.326 ± 0.279
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (3072 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski