Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)

Taxonomy: cellular organisms; Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria;

Average proteome isoelectric point is 6.8

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 50125 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A7N9CMS4|A0A7N9CMS4_MACFA Solute carrier family 25 member 51 OS=Macaca fascicularis OX=9541 GN=SLC25A51 PE=4 SV=1
MM1 pKa = 7.43GCILTCCIDD10 pKa = 4.86SSCGWCRR17 pKa = 11.84GEE19 pKa = 6.09KK20 pKa = 7.41EE21 pKa = 4.12TCYY24 pKa = 10.85EE25 pKa = 3.96SDD27 pKa = 3.07TYY29 pKa = 11.14EE30 pKa = 4.02AVAAATSEE38 pKa = 4.33STTVEE43 pKa = 4.0PGKK46 pKa = 10.53LDD48 pKa = 3.37VGATEE53 pKa = 4.59GHH55 pKa = 6.78DD56 pKa = 3.53LQHH59 pKa = 7.13ISNQKK64 pKa = 8.56MLTVPPEE71 pKa = 4.09DD72 pKa = 3.66SLNLKK77 pKa = 9.71SLPPSEE83 pKa = 4.9EE84 pKa = 4.41DD85 pKa = 3.2NHH87 pKa = 6.72DD88 pKa = 3.87AQILPSPVQGSSEE101 pKa = 4.42DD102 pKa = 3.73NLSLVSLPRR111 pKa = 11.84SEE113 pKa = 6.09DD114 pKa = 3.31YY115 pKa = 11.33DD116 pKa = 4.25GDD118 pKa = 4.63HH119 pKa = 7.88DD120 pKa = 6.93DD121 pKa = 6.4DD122 pKa = 7.51DD123 pKa = 7.38DD124 pKa = 7.46DD125 pKa = 7.33DD126 pKa = 4.78DD127 pKa = 4.77AQVRR131 pKa = 11.84PPFFVFF137 pKa = 4.3

Molecular weight: 14.91 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|G8F3M1|G8F3M1_MACFA Macaca fascicularis brain cDNA clone: QorA-12578 similar to human ras homolog gene family member A (RHOA) mRNA RefSeq: NM_001664.1 OS=Macaca fascicularis OX=9541 PE=2 SV=1
MM1 pKa = 7.1RR2 pKa = 11.84AKK4 pKa = 9.12WRR6 pKa = 11.84KK7 pKa = 9.1KK8 pKa = 9.32RR9 pKa = 11.84MRR11 pKa = 11.84RR12 pKa = 11.84LKK14 pKa = 10.08RR15 pKa = 11.84KK16 pKa = 8.21RR17 pKa = 11.84RR18 pKa = 11.84KK19 pKa = 8.46MRR21 pKa = 11.84QRR23 pKa = 11.84SKK25 pKa = 11.41

Molecular weight: 3.46 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

23262

26863

50125

27273972

7

8797

544.1

60.75

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

6.746 ± 0.01

2.248 ± 0.01

4.809 ± 0.007

7.165 ± 0.015

3.657 ± 0.009

6.367 ± 0.014

2.648 ± 0.006

4.49 ± 0.009

5.959 ± 0.013

9.846 ± 0.014

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.162 ± 0.004

3.75 ± 0.008

6.109 ± 0.015

4.818 ± 0.01

5.584 ± 0.009

8.436 ± 0.014

5.375 ± 0.01

5.956 ± 0.008

1.23 ± 0.004

2.633 ± 0.006
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski