Amino acid dipepetide frequency for Raspberry bushy dwarf virus (isolate Malling Jewel raspberry/R15) (RBDV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.742AlaAla: 7.742 ± 0.985
0.86AlaCys: 0.86 ± 0.426
3.011AlaAsp: 3.011 ± 0.146
2.581AlaGlu: 2.581 ± 0.649
2.151AlaPhe: 2.151 ± 0.493
3.871AlaGly: 3.871 ± 2.181
1.29AlaHis: 1.29 ± 0.64
5.161AlaIle: 5.161 ± 1.349
2.581AlaLys: 2.581 ± 1.284
5.591AlaLeu: 5.591 ± 1.476
0.86AlaMet: 0.86 ± 0.426
3.011AlaAsn: 3.011 ± 0.146
1.29AlaPro: 1.29 ± 0.398
1.72AlaGln: 1.72 ± 1.278
0.86AlaArg: 0.86 ± 1.324
4.731AlaSer: 4.731 ± 2.383
3.011AlaThr: 3.011 ± 1.493
6.882AlaVal: 6.882 ± 2.819
1.29AlaTrp: 1.29 ± 0.64
0.43AlaTyr: 0.43 ± 0.213
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.43CysCys: 0.43 ± 0.213
1.29CysAsp: 1.29 ± 0.64
1.29CysGlu: 1.29 ± 0.64
0.0CysPhe: 0.0 ± 0.0
1.29CysGly: 1.29 ± 0.64
0.86CysHis: 0.86 ± 0.426
0.86CysIle: 0.86 ± 0.503
0.86CysLys: 0.86 ± 0.426
1.72CysLeu: 1.72 ± 0.853
0.43CysMet: 0.43 ± 0.213
1.29CysAsn: 1.29 ± 0.64
2.151CysPro: 2.151 ± 1.066
0.0CysGln: 0.0 ± 0.0
1.29CysArg: 1.29 ± 0.64
1.72CysSer: 1.72 ± 0.853
1.72CysThr: 1.72 ± 0.499
1.72CysVal: 1.72 ± 0.499
0.0CysTrp: 0.0 ± 0.0
0.86CysTyr: 0.86 ± 0.503
0.0CysXaa: 0.0 ± 0.0
Asp
5.591AspAla: 5.591 ± 0.453
0.86AspCys: 0.86 ± 0.426
6.022AspAsp: 6.022 ± 0.941
4.301AspGlu: 4.301 ± 1.107
5.161AspPhe: 5.161 ± 1.844
5.161AspGly: 5.161 ± 2.261
1.29AspHis: 1.29 ± 0.64
2.151AspIle: 2.151 ± 1.066
3.871AspLys: 3.871 ± 0.785
8.172AspLeu: 8.172 ± 1.737
1.72AspMet: 1.72 ± 0.499
3.441AspAsn: 3.441 ± 1.012
3.011AspPro: 3.011 ± 1.493
0.43AspGln: 0.43 ± 0.213
2.151AspArg: 2.151 ± 0.554
8.172AspSer: 8.172 ± 2.236
1.72AspThr: 1.72 ± 1.006
3.011AspVal: 3.011 ± 0.833
0.43AspTrp: 0.43 ± 0.213
1.29AspTyr: 1.29 ± 1.715
0.0AspXaa: 0.0 ± 0.0
Glu
2.581GluAla: 2.581 ± 1.088
2.151GluCys: 2.151 ± 0.493
1.72GluAsp: 1.72 ± 0.499
1.29GluGlu: 1.29 ± 0.398
4.301GluPhe: 4.301 ± 1.152
0.86GluGly: 0.86 ± 0.639
0.43GluHis: 0.43 ± 0.213
6.022GluIle: 6.022 ± 0.654
3.441GluLys: 3.441 ± 0.999
4.731GluLeu: 4.731 ± 0.985
1.29GluMet: 1.29 ± 0.398
4.731GluAsn: 4.731 ± 0.985
0.86GluPro: 0.86 ± 0.426
0.86GluGln: 0.86 ± 0.426
3.441GluArg: 3.441 ± 0.682
4.731GluSer: 4.731 ± 0.775
1.29GluThr: 1.29 ± 0.532
7.312GluVal: 7.312 ± 0.817
0.0GluTrp: 0.0 ± 0.0
1.72GluTyr: 1.72 ± 0.499
0.0GluXaa: 0.0 ± 0.0
Phe
2.151PheAla: 2.151 ± 0.527
0.43PheCys: 0.43 ± 0.213
4.731PheAsp: 4.731 ± 0.775
2.581PheGlu: 2.581 ± 0.649
2.151PhePhe: 2.151 ± 1.066
3.441PheGly: 3.441 ± 1.025
1.29PheHis: 1.29 ± 0.64
2.581PheIle: 2.581 ± 1.279
3.011PheLys: 3.011 ± 0.763
2.151PheLeu: 2.151 ± 1.296
0.0PheMet: 0.0 ± 0.0
2.581PheAsn: 2.581 ± 0.323
2.151PhePro: 2.151 ± 1.066
0.86PheGln: 0.86 ± 0.639
2.151PheArg: 2.151 ± 0.554
7.742PheSer: 7.742 ± 2.345
2.151PheThr: 2.151 ± 0.554
3.011PheVal: 3.011 ± 0.833
0.0PheTrp: 0.0 ± 0.0
2.581PheTyr: 2.581 ± 0.674
0.0PheXaa: 0.0 ± 0.0
Gly
2.151GlyAla: 2.151 ± 0.527
1.72GlyCys: 1.72 ± 0.853
5.161GlyAsp: 5.161 ± 0.986
3.011GlyGlu: 3.011 ± 3.41
1.72GlyPhe: 1.72 ± 0.737
3.441GlyGly: 3.441 ± 1.526
0.0GlyHis: 0.0 ± 0.0
2.581GlyIle: 2.581 ± 0.649
5.591GlyLys: 5.591 ± 1.969
5.591GlyLeu: 5.591 ± 0.72
0.43GlyMet: 0.43 ± 0.213
4.301GlyAsn: 4.301 ± 1.43
2.581GlyPro: 2.581 ± 0.649
0.86GlyGln: 0.86 ± 0.426
2.151GlyArg: 2.151 ± 0.554
7.742GlySer: 7.742 ± 0.968
3.871GlyThr: 3.871 ± 3.027
4.301GlyVal: 4.301 ± 1.43
0.43GlyTrp: 0.43 ± 0.213
3.441GlyTyr: 3.441 ± 1.273
0.0GlyXaa: 0.0 ± 0.0
His
1.72HisAla: 1.72 ± 0.499
0.0HisCys: 0.0 ± 0.0
1.72HisAsp: 1.72 ± 0.853
0.86HisGlu: 0.86 ± 0.426
2.151HisPhe: 2.151 ± 1.066
1.29HisGly: 1.29 ± 0.64
0.43HisHis: 0.43 ± 0.213
0.43HisIle: 0.43 ± 0.213
0.86HisLys: 0.86 ± 0.503
3.011HisLeu: 3.011 ± 0.831
0.86HisMet: 0.86 ± 0.426
0.86HisAsn: 0.86 ± 0.426
0.86HisPro: 0.86 ± 0.426
0.86HisGln: 0.86 ± 0.426
1.72HisArg: 1.72 ± 0.853
1.72HisSer: 1.72 ± 0.394
1.29HisThr: 1.29 ± 0.64
0.0HisVal: 0.0 ± 0.0
0.43HisTrp: 0.43 ± 0.213
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
1.29IleAla: 1.29 ± 0.398
0.86IleCys: 0.86 ± 0.426
3.441IleAsp: 3.441 ± 1.273
1.72IleGlu: 1.72 ± 0.853
2.581IlePhe: 2.581 ± 0.649
2.151IleGly: 2.151 ± 1.066
1.29IleHis: 1.29 ± 0.398
1.29IleIle: 1.29 ± 0.64
5.161IleLys: 5.161 ± 0.347
6.022IleLeu: 6.022 ± 1.41
0.86IleMet: 0.86 ± 0.426
2.581IleAsn: 2.581 ± 2.804
5.591IlePro: 5.591 ± 0.717
2.151IleGln: 2.151 ± 1.066
6.882IleArg: 6.882 ± 1.109
4.731IleSer: 4.731 ± 1.148
2.151IleThr: 2.151 ± 1.066
2.581IleVal: 2.581 ± 1.284
0.86IleTrp: 0.86 ± 0.503
1.29IleTyr: 1.29 ± 0.398
0.0IleXaa: 0.0 ± 0.0
Lys
5.591LysAla: 5.591 ± 1.999
0.86LysCys: 0.86 ± 0.426
3.871LysAsp: 3.871 ± 1.263
5.161LysGlu: 5.161 ± 1.645
5.591LysPhe: 5.591 ± 1.476
3.011LysGly: 3.011 ± 1.684
1.29LysHis: 1.29 ± 0.64
3.871LysIle: 3.871 ± 0.492
2.151LysLys: 2.151 ± 2.107
8.602LysLeu: 8.602 ± 1.52
0.86LysMet: 0.86 ± 0.426
1.72LysAsn: 1.72 ± 0.737
4.731LysPro: 4.731 ± 1.502
0.86LysGln: 0.86 ± 0.639
3.011LysArg: 3.011 ± 0.146
5.591LysSer: 5.591 ± 3.579
3.011LysThr: 3.011 ± 1.493
3.871LysVal: 3.871 ± 1.597
0.43LysTrp: 0.43 ± 0.79
5.161LysTyr: 5.161 ± 0.986
0.0LysXaa: 0.0 ± 0.0
Leu
6.452LeuAla: 6.452 ± 0.655
1.29LeuCys: 1.29 ± 0.64
5.591LeuAsp: 5.591 ± 2.306
4.301LeuGlu: 4.301 ± 1.054
3.011LeuPhe: 3.011 ± 0.831
5.161LeuGly: 5.161 ± 0.347
0.86LeuHis: 0.86 ± 0.426
4.731LeuIle: 4.731 ± 1.133
6.022LeuLys: 6.022 ± 1.141
10.323LeuLeu: 10.323 ± 2.89
0.86LeuMet: 0.86 ± 0.426
5.591LeuAsn: 5.591 ± 1.999
5.161LeuPro: 5.161 ± 2.479
2.151LeuGln: 2.151 ± 0.554
5.161LeuArg: 5.161 ± 1.298
6.882LeuSer: 6.882 ± 3.412
5.161LeuThr: 5.161 ± 1.804
7.742LeuVal: 7.742 ± 0.718
1.29LeuTrp: 1.29 ± 0.64
3.441LeuTyr: 3.441 ± 1.012
0.0LeuXaa: 0.0 ± 0.0
Met
0.43MetAla: 0.43 ± 0.213
0.0MetCys: 0.0 ± 0.0
0.43MetAsp: 0.43 ± 0.213
1.72MetGlu: 1.72 ± 0.853
0.43MetPhe: 0.43 ± 0.662
1.29MetGly: 1.29 ± 0.398
0.0MetHis: 0.0 ± 0.0
0.86MetIle: 0.86 ± 0.426
1.29MetLys: 1.29 ± 0.532
1.72MetLeu: 1.72 ± 0.853
0.0MetMet: 0.0 ± 0.0
0.86MetAsn: 0.86 ± 0.426
0.0MetPro: 0.0 ± 0.0
0.0MetGln: 0.0 ± 0.0
0.43MetArg: 0.43 ± 0.213
3.441MetSer: 3.441 ± 1.889
2.151MetThr: 2.151 ± 0.554
0.86MetVal: 0.86 ± 0.426
0.0MetTrp: 0.0 ± 0.0
0.86MetTyr: 0.86 ± 0.426
0.0MetXaa: 0.0 ± 0.0
Asn
2.581AsnAla: 2.581 ± 1.279
1.29AsnCys: 1.29 ± 0.64
2.581AsnAsp: 2.581 ± 1.064
3.871AsnGlu: 3.871 ± 2.181
3.441AsnPhe: 3.441 ± 1.683
0.86AsnGly: 0.86 ± 0.503
0.43AsnHis: 0.43 ± 0.213
1.72AsnIle: 1.72 ± 0.394
3.441AsnLys: 3.441 ± 0.172
3.011AsnLeu: 3.011 ± 0.146
0.86AsnMet: 0.86 ± 0.426
2.151AsnAsn: 2.151 ± 0.493
1.29AsnPro: 1.29 ± 0.532
1.72AsnGln: 1.72 ± 0.737
3.441AsnArg: 3.441 ± 2.214
3.441AsnSer: 3.441 ± 1.025
3.871AsnThr: 3.871 ± 0.359
6.022AsnVal: 6.022 ± 0.292
0.86AsnTrp: 0.86 ± 0.426
0.43AsnTyr: 0.43 ± 0.662
0.0AsnXaa: 0.0 ± 0.0
Pro
3.871ProAla: 3.871 ± 0.359
0.0ProCys: 0.0 ± 0.0
3.441ProAsp: 3.441 ± 1.025
4.301ProGlu: 4.301 ± 1.107
1.29ProPhe: 1.29 ± 0.64
3.441ProGly: 3.441 ± 1.273
1.29ProHis: 1.29 ± 0.532
5.591ProIle: 5.591 ± 1.969
1.72ProLys: 1.72 ± 0.394
3.871ProLeu: 3.871 ± 0.359
0.86ProMet: 0.86 ± 0.426
0.86ProAsn: 0.86 ± 0.426
1.29ProPro: 1.29 ± 1.715
0.86ProGln: 0.86 ± 0.426
1.29ProArg: 1.29 ± 0.532
2.151ProSer: 2.151 ± 1.296
1.72ProThr: 1.72 ± 0.853
3.871ProVal: 3.871 ± 0.492
0.0ProTrp: 0.0 ± 0.0
2.151ProTyr: 2.151 ± 0.527
0.0ProXaa: 0.0 ± 0.0
Gln
0.86GlnAla: 0.86 ± 0.426
0.0GlnCys: 0.0 ± 0.0
1.29GlnAsp: 1.29 ± 0.398
0.86GlnGlu: 0.86 ± 0.639
0.86GlnPhe: 0.86 ± 0.639
0.86GlnGly: 0.86 ± 0.426
0.43GlnHis: 0.43 ± 0.213
2.151GlnIle: 2.151 ± 0.493
4.731GlnLys: 4.731 ± 1.424
1.29GlnLeu: 1.29 ± 0.64
0.0GlnMet: 0.0 ± 0.0
2.581GlnAsn: 2.581 ± 0.323
1.29GlnPro: 1.29 ± 0.398
1.72GlnGln: 1.72 ± 1.505
1.29GlnArg: 1.29 ± 0.532
0.43GlnSer: 0.43 ± 0.213
0.86GlnThr: 0.86 ± 0.426
3.011GlnVal: 3.011 ± 0.146
0.0GlnTrp: 0.0 ± 0.0
0.86GlnTyr: 0.86 ± 0.639
0.0GlnXaa: 0.0 ± 0.0
Arg
1.29ArgAla: 1.29 ± 0.532
1.72ArgCys: 1.72 ± 0.853
6.022ArgAsp: 6.022 ± 0.703
2.581ArgGlu: 2.581 ± 0.674
0.86ArgPhe: 0.86 ± 0.503
2.581ArgGly: 2.581 ± 1.509
2.581ArgHis: 2.581 ± 1.279
3.011ArgIle: 3.011 ± 0.763
6.022ArgLys: 6.022 ± 2.203
4.301ArgLeu: 4.301 ± 0.986
0.0ArgMet: 0.0 ± 0.0
2.151ArgAsn: 2.151 ± 1.066
0.86ArgPro: 0.86 ± 0.639
0.86ArgGln: 0.86 ± 0.426
3.441ArgArg: 3.441 ± 1.025
3.441ArgSer: 3.441 ± 2.372
3.011ArgThr: 3.011 ± 0.146
2.581ArgVal: 2.581 ± 1.284
1.29ArgTrp: 1.29 ± 0.64
3.871ArgTyr: 3.871 ± 1.919
0.0ArgXaa: 0.0 ± 0.0
Ser
4.301SerAla: 4.301 ± 2.591
3.011SerCys: 3.011 ± 1.493
3.871SerAsp: 3.871 ± 1.919
4.731SerGlu: 4.731 ± 0.265
2.581SerPhe: 2.581 ± 1.284
6.452SerGly: 6.452 ± 0.731
2.581SerHis: 2.581 ± 0.797
3.871SerIle: 3.871 ± 1.263
5.161SerLys: 5.161 ± 1.498
9.462SerLeu: 9.462 ± 1.412
1.72SerMet: 1.72 ± 2.208
3.441SerAsn: 3.441 ± 0.682
3.441SerPro: 3.441 ± 1.526
4.301SerGln: 4.301 ± 2.631
4.731SerArg: 4.731 ± 1.668
12.473SerSer: 12.473 ± 3.371
4.731SerThr: 4.731 ± 0.265
7.312SerVal: 7.312 ± 1.712
2.151SerTrp: 2.151 ± 1.066
3.011SerTyr: 3.011 ± 0.833
0.0SerXaa: 0.0 ± 0.0
Thr
3.011ThrAla: 3.011 ± 0.763
0.0ThrCys: 0.0 ± 0.0
4.731ThrAsp: 4.731 ± 0.775
1.72ThrGlu: 1.72 ± 0.394
1.72ThrPhe: 1.72 ± 0.499
6.452ThrGly: 6.452 ± 1.004
0.86ThrHis: 0.86 ± 0.426
3.871ThrIle: 3.871 ± 1.202
3.011ThrLys: 3.011 ± 1.493
1.72ThrLeu: 1.72 ± 0.853
2.581ThrMet: 2.581 ± 0.278
1.72ThrAsn: 1.72 ± 0.853
2.151ThrPro: 2.151 ± 0.527
1.29ThrGln: 1.29 ± 0.64
2.581ThrArg: 2.581 ± 0.323
3.871ThrSer: 3.871 ± 0.866
1.72ThrThr: 1.72 ± 0.853
5.591ThrVal: 5.591 ± 0.717
0.43ThrTrp: 0.43 ± 0.79
1.72ThrTyr: 1.72 ± 0.853
0.0ThrXaa: 0.0 ± 0.0
Val
3.441ValAla: 3.441 ± 1.012
2.581ValCys: 2.581 ± 1.064
5.591ValAsp: 5.591 ± 1.418
3.871ValGlu: 3.871 ± 0.359
3.441ValPhe: 3.441 ± 1.473
6.882ValGly: 6.882 ± 1.374
2.581ValHis: 2.581 ± 1.279
1.72ValIle: 1.72 ± 0.853
6.022ValLys: 6.022 ± 0.941
5.161ValLeu: 5.161 ± 2.202
1.29ValMet: 1.29 ± 0.64
1.29ValAsn: 1.29 ± 1.715
4.731ValPro: 4.731 ± 0.265
2.581ValGln: 2.581 ± 0.797
3.871ValArg: 3.871 ± 0.359
8.602ValSer: 8.602 ± 2.497
6.452ValThr: 6.452 ± 1.841
4.731ValVal: 4.731 ± 2.213
0.0ValTrp: 0.0 ± 0.0
2.151ValTyr: 2.151 ± 0.882
0.0ValXaa: 0.0 ± 0.0
Trp
1.72TrpAla: 1.72 ± 0.499
0.0TrpCys: 0.0 ± 0.0
1.29TrpAsp: 1.29 ± 0.532
1.72TrpGlu: 1.72 ± 0.853
2.581TrpPhe: 2.581 ± 1.279
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
0.43TrpLeu: 0.43 ± 0.79
0.0TrpMet: 0.0 ± 0.0
0.43TrpAsn: 0.43 ± 0.213
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.43TrpArg: 0.43 ± 0.213
0.43TrpSer: 0.43 ± 0.213
0.0TrpThr: 0.0 ± 0.0
1.72TrpVal: 1.72 ± 0.737
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.151TyrAla: 2.151 ± 1.066
1.72TyrCys: 1.72 ± 0.394
2.151TyrAsp: 2.151 ± 1.066
1.29TyrGlu: 1.29 ± 1.421
1.72TyrPhe: 1.72 ± 0.853
2.581TyrGly: 2.581 ± 0.649
1.29TyrHis: 1.29 ± 0.64
3.011TyrIle: 3.011 ± 0.146
4.301TyrLys: 4.301 ± 1.154
4.301TyrLeu: 4.301 ± 1.154
0.86TyrMet: 0.86 ± 0.392
1.72TyrAsn: 1.72 ± 0.499
0.43TyrPro: 0.43 ± 0.662
1.29TyrGln: 1.29 ± 0.64
2.151TyrArg: 2.151 ± 1.066
1.29TyrSer: 1.29 ± 0.398
1.29TyrThr: 1.29 ± 0.64
0.86TyrVal: 0.86 ± 0.426
0.86TyrTrp: 0.86 ± 1.58
0.86TyrTyr: 0.86 ± 0.503
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (2326 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski