Amino acid dipepetide frequency for Bat polyomavirus 5a

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.431AlaAla: 5.431 ± 3.087
0.0AlaCys: 0.0 ± 0.0
0.679AlaAsp: 0.679 ± 0.728
3.394AlaGlu: 3.394 ± 3.64
0.679AlaPhe: 0.679 ± 0.426
2.037AlaGly: 2.037 ± 0.482
2.716AlaHis: 2.716 ± 1.613
7.468AlaIle: 7.468 ± 2.141
4.073AlaLys: 4.073 ± 1.157
6.11AlaLeu: 6.11 ± 5.673
1.358AlaMet: 1.358 ± 0.932
4.073AlaAsn: 4.073 ± 0.857
2.037AlaPro: 2.037 ± 1.39
1.358AlaGln: 1.358 ± 1.456
4.752AlaArg: 4.752 ± 1.683
2.716AlaSer: 2.716 ± 1.418
4.073AlaThr: 4.073 ± 1.589
4.073AlaVal: 4.073 ± 0.857
0.679AlaTrp: 0.679 ± 0.728
0.679AlaTyr: 0.679 ± 0.574
0.0AlaXaa: 0.0 ± 0.0
Cys
1.358CysAla: 1.358 ± 0.563
0.679CysCys: 0.679 ± 1.165
0.679CysAsp: 0.679 ± 0.574
1.358CysGlu: 1.358 ± 1.079
0.679CysPhe: 0.679 ± 1.165
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
2.716CysIle: 2.716 ± 1.703
2.716CysLys: 2.716 ± 0.966
4.073CysLeu: 4.073 ± 3.238
0.679CysMet: 0.679 ± 0.426
0.0CysAsn: 0.0 ± 0.0
1.358CysPro: 1.358 ± 0.563
0.679CysGln: 0.679 ± 0.426
0.0CysArg: 0.0 ± 0.0
2.716CysSer: 2.716 ± 1.127
0.679CysThr: 0.679 ± 0.426
0.679CysVal: 0.679 ± 1.165
0.0CysTrp: 0.0 ± 0.0
2.037CysTyr: 2.037 ± 1.156
0.0CysXaa: 0.0 ± 0.0
Asp
1.358AspAla: 1.358 ± 1.456
0.679AspCys: 0.679 ± 0.426
2.716AspAsp: 2.716 ± 1.703
3.394AspGlu: 3.394 ± 1.038
2.716AspPhe: 2.716 ± 1.367
4.752AspGly: 4.752 ± 0.544
0.0AspHis: 0.0 ± 0.0
2.037AspIle: 2.037 ± 1.26
6.11AspLys: 6.11 ± 1.534
3.394AspLeu: 3.394 ± 1.801
1.358AspMet: 1.358 ± 1.147
2.037AspAsn: 2.037 ± 1.277
2.037AspPro: 2.037 ± 1.054
2.716AspGln: 2.716 ± 1.175
2.037AspArg: 2.037 ± 0.978
3.394AspSer: 3.394 ± 1.591
1.358AspThr: 1.358 ± 1.147
3.394AspVal: 3.394 ± 1.129
1.358AspTrp: 1.358 ± 0.595
3.394AspTyr: 3.394 ± 0.919
0.0AspXaa: 0.0 ± 0.0
Glu
7.468GluAla: 7.468 ± 4.317
1.358GluCys: 1.358 ± 0.851
3.394GluAsp: 3.394 ± 0.919
6.11GluGlu: 6.11 ± 1.989
3.394GluPhe: 3.394 ± 2.195
5.431GluGly: 5.431 ± 2.431
0.679GluHis: 0.679 ± 0.728
2.037GluIle: 2.037 ± 0.736
4.752GluLys: 4.752 ± 1.359
9.504GluLeu: 9.504 ± 4.491
2.037GluMet: 2.037 ± 0.818
4.752GluAsn: 4.752 ± 1.122
1.358GluPro: 1.358 ± 0.563
1.358GluGln: 1.358 ± 0.595
2.716GluArg: 2.716 ± 1.191
4.752GluSer: 4.752 ± 1.756
1.358GluThr: 1.358 ± 0.775
2.716GluVal: 2.716 ± 1.55
0.0GluTrp: 0.0 ± 0.0
2.037GluTyr: 2.037 ± 1.156
0.0GluXaa: 0.0 ± 0.0
Phe
4.073PheAla: 4.073 ± 1.81
2.716PheCys: 2.716 ± 3.357
0.679PheAsp: 0.679 ± 0.426
2.037PheGlu: 2.037 ± 0.736
0.679PhePhe: 0.679 ± 0.574
1.358PheGly: 1.358 ± 0.563
0.679PheHis: 0.679 ± 0.728
1.358PheIle: 1.358 ± 0.563
4.073PheLys: 4.073 ± 2.554
4.073PheLeu: 4.073 ± 2.005
1.358PheMet: 1.358 ± 1.079
4.073PheAsn: 4.073 ± 0.711
2.716PhePro: 2.716 ± 1.08
0.679PheGln: 0.679 ± 0.728
0.679PheArg: 0.679 ± 0.426
2.716PheSer: 2.716 ± 0.476
3.394PheThr: 3.394 ± 1.338
1.358PheVal: 1.358 ± 0.595
0.679PheTrp: 0.679 ± 1.165
1.358PheTyr: 1.358 ± 0.563
0.0PheXaa: 0.0 ± 0.0
Gly
1.358GlyAla: 1.358 ± 1.456
0.679GlyCys: 0.679 ± 0.426
4.752GlyAsp: 4.752 ± 1.078
5.431GlyGlu: 5.431 ± 1.135
2.037GlyPhe: 2.037 ± 0.482
6.11GlyGly: 6.11 ± 1.528
0.0GlyHis: 0.0 ± 0.0
4.752GlyIle: 4.752 ± 1.533
4.752GlyLys: 4.752 ± 1.98
6.11GlyLeu: 6.11 ± 2.696
0.0GlyMet: 0.0 ± 0.0
1.358GlyAsn: 1.358 ± 1.079
8.147GlyPro: 8.147 ± 1.422
6.789GlyGln: 6.789 ± 1.914
0.679GlyArg: 0.679 ± 0.728
1.358GlySer: 1.358 ± 0.563
2.716GlyThr: 2.716 ± 2.295
6.789GlyVal: 6.789 ± 0.912
0.0GlyTrp: 0.0 ± 0.0
1.358GlyTyr: 1.358 ± 1.147
0.0GlyXaa: 0.0 ± 0.0
His
0.679HisAla: 0.679 ± 0.426
1.358HisCys: 1.358 ± 1.079
0.679HisAsp: 0.679 ± 0.728
1.358HisGlu: 1.358 ± 0.851
0.679HisPhe: 0.679 ± 0.574
0.0HisGly: 0.0 ± 0.0
0.679HisHis: 0.679 ± 0.728
0.0HisIle: 0.0 ± 0.0
0.679HisLys: 0.679 ± 1.165
0.679HisLeu: 0.679 ± 0.574
0.0HisMet: 0.0 ± 0.0
1.358HisAsn: 1.358 ± 1.456
2.037HisPro: 2.037 ± 1.156
0.679HisGln: 0.679 ± 0.728
0.679HisArg: 0.679 ± 0.426
1.358HisSer: 1.358 ± 0.595
0.0HisThr: 0.0 ± 0.0
0.679HisVal: 0.679 ± 0.426
0.679HisTrp: 0.679 ± 0.728
2.037HisTyr: 2.037 ± 0.818
0.0HisXaa: 0.0 ± 0.0
Ile
2.037IleAla: 2.037 ± 1.054
1.358IleCys: 1.358 ± 0.563
2.716IleAsp: 2.716 ± 1.703
4.073IleGlu: 4.073 ± 0.964
0.679IlePhe: 0.679 ± 0.426
2.037IleGly: 2.037 ± 0.482
0.0IleHis: 0.0 ± 0.0
2.716IleIle: 2.716 ± 0.476
2.037IleLys: 2.037 ± 1.277
6.11IleLeu: 6.11 ± 2.208
0.0IleMet: 0.0 ± 0.0
5.431IleAsn: 5.431 ± 1.604
3.394IlePro: 3.394 ± 1.091
2.716IleGln: 2.716 ± 0.476
0.679IleArg: 0.679 ± 0.728
0.679IleSer: 0.679 ± 0.728
4.073IleThr: 4.073 ± 1.806
4.073IleVal: 4.073 ± 1.81
0.679IleTrp: 0.679 ± 0.728
4.073IleTyr: 4.073 ± 1.97
0.0IleXaa: 0.0 ± 0.0
Lys
3.394LysAla: 3.394 ± 1.591
2.037LysCys: 2.037 ± 0.818
1.358LysAsp: 1.358 ± 0.563
4.073LysGlu: 4.073 ± 2.076
2.716LysPhe: 2.716 ± 1.367
5.431LysGly: 5.431 ± 1.855
1.358LysHis: 1.358 ± 0.851
2.716LysIle: 2.716 ± 2.251
5.431LysLys: 5.431 ± 1.614
6.789LysLeu: 6.789 ± 1.021
3.394LysMet: 3.394 ± 2.195
4.752LysAsn: 4.752 ± 1.359
4.073LysPro: 4.073 ± 1.974
2.037LysGln: 2.037 ± 1.156
7.468LysArg: 7.468 ± 1.493
1.358LysSer: 1.358 ± 0.563
6.789LysThr: 6.789 ± 2.791
4.073LysVal: 4.073 ± 1.97
0.0LysTrp: 0.0 ± 0.0
2.037LysTyr: 2.037 ± 0.736
0.0LysXaa: 0.0 ± 0.0
Leu
4.752LeuAla: 4.752 ± 3.462
2.037LeuCys: 2.037 ± 0.978
6.789LeuAsp: 6.789 ± 1.905
7.468LeuGlu: 7.468 ± 2.089
6.11LeuPhe: 6.11 ± 1.27
4.073LeuGly: 4.073 ± 1.982
1.358LeuHis: 1.358 ± 0.563
4.073LeuIle: 4.073 ± 1.372
4.073LeuLys: 4.073 ± 1.406
13.578LeuLeu: 13.578 ± 1.228
1.358LeuMet: 1.358 ± 0.471
6.11LeuAsn: 6.11 ± 1.534
7.468LeuPro: 7.468 ± 2.17
8.147LeuGln: 8.147 ± 1.782
4.073LeuArg: 4.073 ± 1.345
6.789LeuSer: 6.789 ± 1.839
3.394LeuThr: 3.394 ± 1.415
5.431LeuVal: 5.431 ± 1.342
2.037LeuTrp: 2.037 ± 1.163
2.037LeuTyr: 2.037 ± 1.163
0.0LeuXaa: 0.0 ± 0.0
Met
2.037MetAla: 2.037 ± 0.482
2.037MetCys: 2.037 ± 1.156
3.394MetAsp: 3.394 ± 1.978
0.679MetGlu: 0.679 ± 0.574
2.037MetPhe: 2.037 ± 1.277
2.037MetGly: 2.037 ± 0.482
0.0MetHis: 0.0 ± 0.0
0.679MetIle: 0.679 ± 0.574
2.037MetLys: 2.037 ± 1.156
2.037MetLeu: 2.037 ± 1.39
2.716MetMet: 2.716 ± 1.286
3.394MetAsn: 3.394 ± 1.662
0.0MetPro: 0.0 ± 0.0
1.358MetGln: 1.358 ± 1.079
0.0MetArg: 0.0 ± 0.0
0.0MetSer: 0.0 ± 0.0
1.358MetThr: 1.358 ± 1.147
0.0MetVal: 0.0 ± 0.0
1.358MetTrp: 1.358 ± 1.147
2.037MetTyr: 2.037 ± 1.721
0.0MetXaa: 0.0 ± 0.0
Asn
3.394AsnAla: 3.394 ± 2.195
1.358AsnCys: 1.358 ± 0.851
2.037AsnAsp: 2.037 ± 0.818
5.431AsnGlu: 5.431 ± 1.649
0.679AsnPhe: 0.679 ± 0.426
2.716AsnGly: 2.716 ± 1.127
1.358AsnHis: 1.358 ± 0.775
5.431AsnIle: 5.431 ± 1.649
4.073AsnLys: 4.073 ± 2.311
6.789AsnLeu: 6.789 ± 2.9
1.358AsnMet: 1.358 ± 1.147
2.716AsnAsn: 2.716 ± 1.127
4.073AsnPro: 4.073 ± 1.254
0.679AsnGln: 0.679 ± 0.574
0.679AsnArg: 0.679 ± 0.426
3.394AsnSer: 3.394 ± 1.832
4.073AsnThr: 4.073 ± 0.857
3.394AsnVal: 3.394 ± 0.919
0.0AsnTrp: 0.0 ± 0.0
2.037AsnTyr: 2.037 ± 1.163
0.0AsnXaa: 0.0 ± 0.0
Pro
4.073ProAla: 4.073 ± 1.982
1.358ProCys: 1.358 ± 0.851
6.11ProAsp: 6.11 ± 1.897
2.716ProGlu: 2.716 ± 1.703
2.037ProPhe: 2.037 ± 1.277
6.11ProGly: 6.11 ± 1.199
0.679ProHis: 0.679 ± 0.728
1.358ProIle: 1.358 ± 0.563
5.431ProLys: 5.431 ± 1.37
4.752ProLeu: 4.752 ± 1.294
3.394ProMet: 3.394 ± 1.586
0.0ProAsn: 0.0 ± 0.0
5.431ProPro: 5.431 ± 0.952
1.358ProGln: 1.358 ± 0.595
1.358ProArg: 1.358 ± 1.147
5.431ProSer: 5.431 ± 1.466
2.037ProThr: 2.037 ± 0.978
4.073ProVal: 4.073 ± 2.804
0.0ProTrp: 0.0 ± 0.0
0.679ProTyr: 0.679 ± 0.574
0.0ProXaa: 0.0 ± 0.0
Gln
2.716GlnAla: 2.716 ± 1.191
0.679GlnCys: 0.679 ± 0.426
2.037GlnAsp: 2.037 ± 0.978
1.358GlnGlu: 1.358 ± 0.851
2.037GlnPhe: 2.037 ± 1.054
3.394GlnGly: 3.394 ± 1.038
1.358GlnHis: 1.358 ± 1.079
2.716GlnIle: 2.716 ± 0.476
5.431GlnLys: 5.431 ± 0.87
2.037GlnLeu: 2.037 ± 1.26
1.358GlnMet: 1.358 ± 0.563
2.716GlnAsn: 2.716 ± 1.703
2.037GlnPro: 2.037 ± 1.054
2.716GlnGln: 2.716 ± 1.099
2.716GlnArg: 2.716 ± 1.08
1.358GlnSer: 1.358 ± 0.851
3.394GlnThr: 3.394 ± 0.712
4.073GlnVal: 4.073 ± 1.556
0.0GlnTrp: 0.0 ± 0.0
0.679GlnTyr: 0.679 ± 0.426
0.0GlnXaa: 0.0 ± 0.0
Arg
1.358ArgAla: 1.358 ± 1.456
0.0ArgCys: 0.0 ± 0.0
2.716ArgAsp: 2.716 ± 1.08
4.073ArgGlu: 4.073 ± 3.249
3.394ArgPhe: 3.394 ± 1.159
1.358ArgGly: 1.358 ± 0.563
0.0ArgHis: 0.0 ± 0.0
1.358ArgIle: 1.358 ± 0.563
3.394ArgLys: 3.394 ± 0.755
2.037ArgLeu: 2.037 ± 1.26
3.394ArgMet: 3.394 ± 1.091
2.716ArgAsn: 2.716 ± 1.127
2.037ArgPro: 2.037 ± 0.736
0.679ArgGln: 0.679 ± 0.728
4.752ArgArg: 4.752 ± 3.226
0.679ArgSer: 0.679 ± 0.426
1.358ArgThr: 1.358 ± 0.775
2.037ArgVal: 2.037 ± 0.482
1.358ArgTrp: 1.358 ± 1.379
3.394ArgTyr: 3.394 ± 1.401
0.0ArgXaa: 0.0 ± 0.0
Ser
4.752SerAla: 4.752 ± 3.226
1.358SerCys: 1.358 ± 1.147
2.716SerAsp: 2.716 ± 1.099
2.716SerGlu: 2.716 ± 1.175
4.073SerPhe: 4.073 ± 1.472
3.394SerGly: 3.394 ± 0.919
2.037SerHis: 2.037 ± 0.818
2.037SerIle: 2.037 ± 0.482
1.358SerLys: 1.358 ± 1.158
8.826SerLeu: 8.826 ± 2.9
1.358SerMet: 1.358 ± 1.456
2.716SerAsn: 2.716 ± 1.175
1.358SerPro: 1.358 ± 0.851
2.716SerGln: 2.716 ± 1.703
3.394SerArg: 3.394 ± 1.129
6.789SerSer: 6.789 ± 1.744
2.716SerThr: 2.716 ± 1.127
4.752SerVal: 4.752 ± 2.004
0.679SerTrp: 0.679 ± 0.728
0.0SerTyr: 0.0 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
0.679ThrAla: 0.679 ± 0.728
2.037ThrCys: 2.037 ± 0.978
3.394ThrAsp: 3.394 ± 1.338
4.073ThrGlu: 4.073 ± 0.857
2.037ThrPhe: 2.037 ± 0.482
4.752ThrGly: 4.752 ± 2.47
1.358ThrHis: 1.358 ± 0.851
0.679ThrIle: 0.679 ± 0.574
2.037ThrLys: 2.037 ± 1.054
4.752ThrLeu: 4.752 ± 1.918
1.358ThrMet: 1.358 ± 0.851
1.358ThrAsn: 1.358 ± 1.147
4.073ThrPro: 4.073 ± 0.919
3.394ThrGln: 3.394 ± 1.568
2.716ThrArg: 2.716 ± 0.476
4.752ThrSer: 4.752 ± 1.985
6.789ThrThr: 6.789 ± 1.51
3.394ThrVal: 3.394 ± 0.755
0.0ThrTrp: 0.0 ± 0.0
2.037ThrTyr: 2.037 ± 1.054
0.0ThrXaa: 0.0 ± 0.0
Val
5.431ValAla: 5.431 ± 1.522
1.358ValCys: 1.358 ± 1.079
2.037ValAsp: 2.037 ± 1.054
4.752ValGlu: 4.752 ± 0.858
2.037ValPhe: 2.037 ± 1.156
4.752ValGly: 4.752 ± 1.798
0.0ValHis: 0.0 ± 0.0
4.752ValIle: 4.752 ± 1.359
4.752ValLys: 4.752 ± 1.918
5.431ValLeu: 5.431 ± 1.735
0.0ValMet: 0.0 ± 0.0
4.073ValAsn: 4.073 ± 0.919
2.037ValPro: 2.037 ± 0.482
2.037ValGln: 2.037 ± 1.26
1.358ValArg: 1.358 ± 0.775
5.431ValSer: 5.431 ± 1.45
4.752ValThr: 4.752 ± 1.533
4.073ValVal: 4.073 ± 0.964
0.679ValTrp: 0.679 ± 0.426
2.037ValTyr: 2.037 ± 0.482
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
2.037TrpGlu: 2.037 ± 1.276
0.679TrpPhe: 0.679 ± 1.165
2.037TrpGly: 2.037 ± 1.153
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.679TrpLys: 0.679 ± 0.426
0.679TrpLeu: 0.679 ± 0.728
0.679TrpMet: 0.679 ± 0.728
0.679TrpAsn: 0.679 ± 0.426
0.0TrpPro: 0.0 ± 0.0
1.358TrpGln: 1.358 ± 1.079
0.679TrpArg: 0.679 ± 0.728
0.679TrpSer: 0.679 ± 0.728
0.0TrpThr: 0.0 ± 0.0
0.679TrpVal: 0.679 ± 0.728
0.0TrpTrp: 0.0 ± 0.0
0.679TrpTyr: 0.679 ± 0.426
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.037TyrAla: 2.037 ± 1.276
0.0TyrCys: 0.0 ± 0.0
1.358TyrAsp: 1.358 ± 1.456
0.679TyrGlu: 0.679 ± 0.574
1.358TyrPhe: 1.358 ± 0.563
3.394TyrGly: 3.394 ± 1.038
2.037TyrHis: 2.037 ± 1.156
0.679TyrIle: 0.679 ± 0.728
3.394TyrLys: 3.394 ± 2.195
4.073TyrLeu: 4.073 ± 1.141
1.358TyrMet: 1.358 ± 0.563
1.358TyrAsn: 1.358 ± 0.851
2.716TyrPro: 2.716 ± 1.601
1.358TyrGln: 1.358 ± 1.079
0.679TyrArg: 0.679 ± 0.574
3.394TyrSer: 3.394 ± 1.401
1.358TyrThr: 1.358 ± 0.563
2.037TyrVal: 2.037 ± 0.818
1.358TyrTrp: 1.358 ± 0.563
3.394TyrTyr: 3.394 ± 1.219
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (1474 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski