Amino acid dipepetide frequency for Pohorje myodes paramyxovirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.232AlaAla: 3.232 ± 0.675
0.808AlaCys: 0.808 ± 0.37
4.202AlaAsp: 4.202 ± 1.122
3.07AlaGlu: 3.07 ± 1.156
1.616AlaPhe: 1.616 ± 0.611
3.232AlaGly: 3.232 ± 0.572
1.778AlaHis: 1.778 ± 0.794
4.363AlaIle: 4.363 ± 1.727
1.778AlaLys: 1.778 ± 0.403
5.979AlaLeu: 5.979 ± 1.634
1.778AlaMet: 1.778 ± 0.65
3.555AlaAsn: 3.555 ± 1.117
2.101AlaPro: 2.101 ± 0.634
1.778AlaGln: 1.778 ± 0.403
2.424AlaArg: 2.424 ± 0.402
3.717AlaSer: 3.717 ± 0.806
3.717AlaThr: 3.717 ± 1.203
2.262AlaVal: 2.262 ± 0.775
0.808AlaTrp: 0.808 ± 0.299
1.616AlaTyr: 1.616 ± 0.532
0.0AlaXaa: 0.0 ± 0.0
Cys
0.646CysAla: 0.646 ± 0.641
0.162CysCys: 0.162 ± 0.105
0.646CysAsp: 0.646 ± 0.192
0.323CysGlu: 0.323 ± 0.198
0.808CysPhe: 0.808 ± 0.37
1.293CysGly: 1.293 ± 0.565
0.162CysHis: 0.162 ± 0.105
0.485CysIle: 0.485 ± 0.316
0.97CysLys: 0.97 ± 0.514
1.131CysLeu: 1.131 ± 0.291
0.162CysMet: 0.162 ± 0.145
0.808CysAsn: 0.808 ± 0.411
1.131CysPro: 1.131 ± 0.82
0.646CysGln: 0.646 ± 0.328
1.778CysArg: 1.778 ± 0.84
1.454CysSer: 1.454 ± 0.473
1.454CysThr: 1.454 ± 0.454
0.97CysVal: 0.97 ± 0.346
0.323CysTrp: 0.323 ± 0.21
1.616CysTyr: 1.616 ± 0.445
0.0CysXaa: 0.0 ± 0.0
Asp
2.586AspAla: 2.586 ± 0.449
0.485AspCys: 0.485 ± 0.253
3.394AspAsp: 3.394 ± 1.047
3.717AspGlu: 3.717 ± 0.911
2.262AspPhe: 2.262 ± 0.517
2.262AspGly: 2.262 ± 1.285
1.454AspHis: 1.454 ± 0.387
4.525AspIle: 4.525 ± 1.074
2.747AspLys: 2.747 ± 0.454
6.141AspLeu: 6.141 ± 0.893
1.131AspMet: 1.131 ± 0.575
3.394AspAsn: 3.394 ± 0.645
4.525AspPro: 4.525 ± 0.673
2.909AspGln: 2.909 ± 0.661
2.909AspArg: 2.909 ± 0.627
3.555AspSer: 3.555 ± 1.06
4.363AspThr: 4.363 ± 0.901
3.555AspVal: 3.555 ± 0.481
0.162AspTrp: 0.162 ± 0.105
2.424AspTyr: 2.424 ± 0.792
0.0AspXaa: 0.0 ± 0.0
Glu
2.586GluAla: 2.586 ± 0.313
1.616GluCys: 1.616 ± 0.512
4.363GluAsp: 4.363 ± 0.723
2.747GluGlu: 2.747 ± 1.289
2.586GluPhe: 2.586 ± 0.663
3.555GluGly: 3.555 ± 0.775
0.808GluHis: 0.808 ± 0.302
3.555GluIle: 3.555 ± 0.641
2.586GluLys: 2.586 ± 0.596
3.878GluLeu: 3.878 ± 0.82
1.616GluMet: 1.616 ± 0.471
1.939GluAsn: 1.939 ± 0.518
2.424GluPro: 2.424 ± 0.587
2.424GluGln: 2.424 ± 0.701
3.232GluArg: 3.232 ± 0.986
4.04GluSer: 4.04 ± 1.058
4.848GluThr: 4.848 ± 1.013
2.586GluVal: 2.586 ± 0.417
1.293GluTrp: 1.293 ± 0.418
2.262GluTyr: 2.262 ± 0.385
0.0GluXaa: 0.0 ± 0.0
Phe
2.101PheAla: 2.101 ± 0.244
0.97PheCys: 0.97 ± 0.278
1.616PheAsp: 1.616 ± 0.326
1.616PheGlu: 1.616 ± 0.707
1.616PhePhe: 1.616 ± 0.571
1.293PheGly: 1.293 ± 0.319
0.323PheHis: 0.323 ± 0.129
2.747PheIle: 2.747 ± 0.426
2.747PheLys: 2.747 ± 0.735
3.394PheLeu: 3.394 ± 0.663
1.939PheMet: 1.939 ± 0.743
1.939PheAsn: 1.939 ± 0.335
1.939PhePro: 1.939 ± 0.414
0.808PheGln: 0.808 ± 0.37
2.586PheArg: 2.586 ± 0.938
3.232PheSer: 3.232 ± 0.636
0.808PheThr: 0.808 ± 0.279
1.293PheVal: 1.293 ± 0.473
0.646PheTrp: 0.646 ± 0.328
0.808PheTyr: 0.808 ± 0.232
0.0PheXaa: 0.0 ± 0.0
Gly
3.717GlyAla: 3.717 ± 1.009
0.97GlyCys: 0.97 ± 0.393
3.878GlyAsp: 3.878 ± 0.83
2.262GlyGlu: 2.262 ± 0.66
2.262GlyPhe: 2.262 ± 0.935
3.717GlyGly: 3.717 ± 0.781
2.101GlyHis: 2.101 ± 1.001
3.232GlyIle: 3.232 ± 0.762
3.394GlyLys: 3.394 ± 0.879
4.202GlyLeu: 4.202 ± 0.673
1.939GlyMet: 1.939 ± 0.718
2.586GlyAsn: 2.586 ± 0.512
1.616GlyPro: 1.616 ± 0.415
1.939GlyGln: 1.939 ± 0.746
2.586GlyArg: 2.586 ± 0.903
5.979GlySer: 5.979 ± 1.813
2.424GlyThr: 2.424 ± 0.919
4.202GlyVal: 4.202 ± 1.052
0.485GlyTrp: 0.485 ± 0.321
1.778GlyTyr: 1.778 ± 0.589
0.0GlyXaa: 0.0 ± 0.0
His
1.454HisAla: 1.454 ± 0.549
0.323HisCys: 0.323 ± 0.129
1.131HisAsp: 1.131 ± 0.821
1.778HisGlu: 1.778 ± 0.534
0.646HisPhe: 0.646 ± 0.258
1.131HisGly: 1.131 ± 0.381
0.646HisHis: 0.646 ± 0.44
1.131HisIle: 1.131 ± 0.363
0.646HisLys: 0.646 ± 0.396
1.131HisLeu: 1.131 ± 0.572
0.323HisMet: 0.323 ± 0.21
1.778HisAsn: 1.778 ± 0.819
1.939HisPro: 1.939 ± 0.835
0.808HisGln: 0.808 ± 0.35
0.808HisArg: 0.808 ± 0.345
1.293HisSer: 1.293 ± 0.783
2.262HisThr: 2.262 ± 1.353
0.808HisVal: 0.808 ± 0.22
0.162HisTrp: 0.162 ± 0.152
0.485HisTyr: 0.485 ± 0.306
0.0HisXaa: 0.0 ± 0.0
Ile
3.717IleAla: 3.717 ± 1.166
2.262IleCys: 2.262 ± 0.475
4.848IleAsp: 4.848 ± 0.742
3.555IleGlu: 3.555 ± 0.526
1.778IlePhe: 1.778 ± 0.281
4.04IleGly: 4.04 ± 0.397
1.616IleHis: 1.616 ± 0.563
5.495IleIle: 5.495 ± 1.358
5.656IleLys: 5.656 ± 1.478
5.818IleLeu: 5.818 ± 1.156
2.586IleMet: 2.586 ± 0.486
5.171IleAsn: 5.171 ± 0.603
3.878IlePro: 3.878 ± 0.516
3.394IleGln: 3.394 ± 0.904
2.909IleArg: 2.909 ± 0.846
4.202IleSer: 4.202 ± 1.749
5.979IleThr: 5.979 ± 1.009
2.747IleVal: 2.747 ± 0.662
1.131IleTrp: 1.131 ± 0.494
4.363IleTyr: 4.363 ± 1.113
0.0IleXaa: 0.0 ± 0.0
Lys
3.717LysAla: 3.717 ± 0.647
0.97LysCys: 0.97 ± 0.514
3.232LysAsp: 3.232 ± 0.856
4.363LysGlu: 4.363 ± 0.653
1.616LysPhe: 1.616 ± 0.467
2.909LysGly: 2.909 ± 1.079
0.808LysHis: 0.808 ± 0.282
4.202LysIle: 4.202 ± 0.936
2.747LysLys: 2.747 ± 0.891
5.495LysLeu: 5.495 ± 0.674
1.778LysMet: 1.778 ± 0.74
4.04LysAsn: 4.04 ± 0.583
2.909LysPro: 2.909 ± 1.302
1.616LysGln: 1.616 ± 0.347
2.747LysArg: 2.747 ± 0.437
4.686LysSer: 4.686 ± 1.019
2.586LysThr: 2.586 ± 1.029
3.717LysVal: 3.717 ± 1.261
0.162LysTrp: 0.162 ± 0.105
2.747LysTyr: 2.747 ± 0.807
0.0LysXaa: 0.0 ± 0.0
Leu
4.848LeuAla: 4.848 ± 1.268
1.616LeuCys: 1.616 ± 0.326
7.757LeuAsp: 7.757 ± 1.125
3.878LeuGlu: 3.878 ± 0.722
3.07LeuPhe: 3.07 ± 0.897
5.333LeuGly: 5.333 ± 0.947
1.778LeuHis: 1.778 ± 0.459
9.535LeuIle: 9.535 ± 1.243
3.717LeuLys: 3.717 ± 0.845
6.141LeuLeu: 6.141 ± 1.494
1.454LeuMet: 1.454 ± 0.569
6.787LeuAsn: 6.787 ± 1.503
2.101LeuPro: 2.101 ± 0.635
3.555LeuGln: 3.555 ± 0.785
6.141LeuArg: 6.141 ± 1.166
8.403LeuSer: 8.403 ± 1.39
5.656LeuThr: 5.656 ± 0.858
3.394LeuVal: 3.394 ± 1.016
0.485LeuTrp: 0.485 ± 0.154
2.747LeuTyr: 2.747 ± 0.63
0.0LeuXaa: 0.0 ± 0.0
Met
1.293MetAla: 1.293 ± 0.553
0.485MetCys: 0.485 ± 0.18
1.131MetAsp: 1.131 ± 0.568
2.424MetGlu: 2.424 ± 0.656
0.485MetPhe: 0.485 ± 0.154
1.454MetGly: 1.454 ± 0.44
0.323MetHis: 0.323 ± 0.247
2.747MetIle: 2.747 ± 0.423
2.586MetLys: 2.586 ± 0.537
3.07MetLeu: 3.07 ± 1.241
0.808MetMet: 0.808 ± 0.202
1.778MetAsn: 1.778 ± 0.509
0.646MetPro: 0.646 ± 0.212
0.485MetGln: 0.485 ± 0.353
0.97MetArg: 0.97 ± 0.31
2.262MetSer: 2.262 ± 0.351
1.939MetThr: 1.939 ± 0.557
2.424MetVal: 2.424 ± 0.768
0.646MetTrp: 0.646 ± 0.322
1.131MetTyr: 1.131 ± 0.372
0.0MetXaa: 0.0 ± 0.0
Asn
3.232AsnAla: 3.232 ± 1.576
1.131AsnCys: 1.131 ± 0.303
2.424AsnAsp: 2.424 ± 0.614
2.747AsnGlu: 2.747 ± 0.47
1.616AsnPhe: 1.616 ± 0.446
2.262AsnGly: 2.262 ± 0.613
0.97AsnHis: 0.97 ± 0.49
5.656AsnIle: 5.656 ± 1.293
4.04AsnLys: 4.04 ± 0.542
4.686AsnLeu: 4.686 ± 0.865
2.262AsnMet: 2.262 ± 1.042
3.878AsnAsn: 3.878 ± 0.743
5.171AsnPro: 5.171 ± 1.086
1.939AsnGln: 1.939 ± 0.322
2.909AsnArg: 2.909 ± 0.671
3.555AsnSer: 3.555 ± 0.754
4.686AsnThr: 4.686 ± 0.76
1.778AsnVal: 1.778 ± 0.579
1.131AsnTrp: 1.131 ± 0.411
3.232AsnTyr: 3.232 ± 0.357
0.0AsnXaa: 0.0 ± 0.0
Pro
2.262ProAla: 2.262 ± 0.743
0.808ProCys: 0.808 ± 0.723
2.262ProAsp: 2.262 ± 0.73
2.909ProGlu: 2.909 ± 1.133
1.293ProPhe: 1.293 ± 0.533
3.878ProGly: 3.878 ± 1.358
1.616ProHis: 1.616 ± 0.719
3.232ProIle: 3.232 ± 0.82
3.717ProLys: 3.717 ± 0.734
3.555ProLeu: 3.555 ± 0.989
0.97ProMet: 0.97 ± 0.248
3.555ProAsn: 3.555 ± 1.012
3.394ProPro: 3.394 ± 1.019
1.939ProGln: 1.939 ± 0.978
3.232ProArg: 3.232 ± 0.646
4.363ProSer: 4.363 ± 1.375
4.525ProThr: 4.525 ± 2.681
2.747ProVal: 2.747 ± 0.534
0.162ProTrp: 0.162 ± 0.215
2.101ProTyr: 2.101 ± 0.693
0.0ProXaa: 0.0 ± 0.0
Gln
1.778GlnAla: 1.778 ± 0.264
0.97GlnCys: 0.97 ± 0.868
2.262GlnAsp: 2.262 ± 0.473
2.424GlnGlu: 2.424 ± 0.66
0.808GlnPhe: 0.808 ± 0.269
0.97GlnGly: 0.97 ± 0.526
0.485GlnHis: 0.485 ± 0.253
3.394GlnIle: 3.394 ± 0.694
1.939GlnLys: 1.939 ± 0.41
3.878GlnLeu: 3.878 ± 0.87
0.646GlnMet: 0.646 ± 0.221
1.616GlnAsn: 1.616 ± 0.447
2.586GlnPro: 2.586 ± 1.005
2.424GlnGln: 2.424 ± 0.605
1.778GlnArg: 1.778 ± 0.532
2.586GlnSer: 2.586 ± 0.417
3.394GlnThr: 3.394 ± 1.084
2.101GlnVal: 2.101 ± 0.658
0.162GlnTrp: 0.162 ± 0.145
1.616GlnTyr: 1.616 ± 0.349
0.0GlnXaa: 0.0 ± 0.0
Arg
3.878ArgAla: 3.878 ± 1.252
0.323ArgCys: 0.323 ± 0.129
3.555ArgAsp: 3.555 ± 0.803
3.232ArgGlu: 3.232 ± 0.995
1.778ArgPhe: 1.778 ± 0.608
3.555ArgGly: 3.555 ± 0.994
0.808ArgHis: 0.808 ± 0.274
3.555ArgIle: 3.555 ± 0.729
3.555ArgLys: 3.555 ± 0.778
4.848ArgLeu: 4.848 ± 1.122
1.616ArgMet: 1.616 ± 0.573
2.101ArgAsn: 2.101 ± 0.624
2.424ArgPro: 2.424 ± 0.763
1.293ArgGln: 1.293 ± 0.495
4.363ArgArg: 4.363 ± 0.871
4.202ArgSer: 4.202 ± 0.739
3.07ArgThr: 3.07 ± 0.92
2.909ArgVal: 2.909 ± 0.554
0.485ArgTrp: 0.485 ± 0.241
0.97ArgTyr: 0.97 ± 0.473
0.0ArgXaa: 0.0 ± 0.0
Ser
4.04SerAla: 4.04 ± 1.187
1.293SerCys: 1.293 ± 0.408
3.878SerAsp: 3.878 ± 1.555
4.202SerGlu: 4.202 ± 0.565
2.909SerPhe: 2.909 ± 0.773
2.909SerGly: 2.909 ± 0.595
2.424SerHis: 2.424 ± 0.724
4.848SerIle: 4.848 ± 1.054
4.04SerLys: 4.04 ± 0.846
8.727SerLeu: 8.727 ± 1.616
2.424SerMet: 2.424 ± 0.728
4.363SerAsn: 4.363 ± 0.606
4.686SerPro: 4.686 ± 2.261
3.232SerGln: 3.232 ± 0.515
4.525SerArg: 4.525 ± 0.888
7.595SerSer: 7.595 ± 0.994
5.979SerThr: 5.979 ± 1.274
4.202SerVal: 4.202 ± 0.853
0.808SerTrp: 0.808 ± 0.448
3.07SerTyr: 3.07 ± 0.879
0.0SerXaa: 0.0 ± 0.0
Thr
4.363ThrAla: 4.363 ± 1.405
0.808ThrCys: 0.808 ± 0.311
3.07ThrAsp: 3.07 ± 0.953
4.04ThrGlu: 4.04 ± 1.457
2.586ThrPhe: 2.586 ± 0.535
5.01ThrGly: 5.01 ± 1.104
0.646ThrHis: 0.646 ± 0.392
5.818ThrIle: 5.818 ± 1.298
5.171ThrLys: 5.171 ± 0.364
5.495ThrLeu: 5.495 ± 1.555
1.778ThrMet: 1.778 ± 0.29
3.878ThrAsn: 3.878 ± 0.594
3.717ThrPro: 3.717 ± 2.014
2.909ThrGln: 2.909 ± 0.694
2.586ThrArg: 2.586 ± 0.966
6.464ThrSer: 6.464 ± 2.086
9.696ThrThr: 9.696 ± 3.803
3.232ThrVal: 3.232 ± 0.728
0.323ThrTrp: 0.323 ± 0.217
3.07ThrTyr: 3.07 ± 0.717
0.0ThrXaa: 0.0 ± 0.0
Val
3.232ValAla: 3.232 ± 0.723
0.162ValCys: 0.162 ± 0.223
3.394ValAsp: 3.394 ± 0.64
2.747ValGlu: 2.747 ± 0.753
2.424ValPhe: 2.424 ± 0.591
3.717ValGly: 3.717 ± 0.842
1.131ValHis: 1.131 ± 0.261
2.424ValIle: 2.424 ± 0.82
2.101ValLys: 2.101 ± 0.616
5.171ValLeu: 5.171 ± 1.075
1.939ValMet: 1.939 ± 0.613
2.747ValAsn: 2.747 ± 0.606
2.424ValPro: 2.424 ± 0.476
2.101ValGln: 2.101 ± 0.851
2.101ValArg: 2.101 ± 0.43
3.717ValSer: 3.717 ± 0.975
3.07ValThr: 3.07 ± 0.263
1.939ValVal: 1.939 ± 0.675
0.0ValTrp: 0.0 ± 0.0
2.101ValTyr: 2.101 ± 0.269
0.0ValXaa: 0.0 ± 0.0
Trp
0.485TrpAla: 0.485 ± 0.186
0.162TrpCys: 0.162 ± 0.145
0.323TrpAsp: 0.323 ± 0.21
0.646TrpGlu: 0.646 ± 0.302
0.485TrpPhe: 0.485 ± 0.186
0.323TrpGly: 0.323 ± 0.226
0.162TrpHis: 0.162 ± 0.145
0.97TrpIle: 0.97 ± 0.202
0.646TrpLys: 0.646 ± 0.463
0.808TrpLeu: 0.808 ± 0.652
0.323TrpMet: 0.323 ± 0.129
0.646TrpAsn: 0.646 ± 0.368
0.162TrpPro: 0.162 ± 0.105
0.323TrpGln: 0.323 ± 0.18
0.485TrpArg: 0.485 ± 0.308
0.97TrpSer: 0.97 ± 0.301
0.485TrpThr: 0.485 ± 0.308
0.646TrpVal: 0.646 ± 0.339
0.162TrpTrp: 0.162 ± 0.105
0.485TrpTyr: 0.485 ± 0.186
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.646TyrAla: 0.646 ± 0.203
0.646TyrCys: 0.646 ± 0.368
1.293TyrAsp: 1.293 ± 0.396
2.262TyrGlu: 2.262 ± 1.157
1.778TyrPhe: 1.778 ± 0.673
2.424TyrGly: 2.424 ± 0.545
0.646TyrHis: 0.646 ± 0.245
3.232TyrIle: 3.232 ± 0.656
2.262TyrLys: 2.262 ± 0.441
4.848TyrLeu: 4.848 ± 0.743
1.454TyrMet: 1.454 ± 0.363
2.747TyrAsn: 2.747 ± 0.446
2.747TyrPro: 2.747 ± 0.526
1.293TyrGln: 1.293 ± 0.422
1.454TyrArg: 1.454 ± 0.557
3.878TyrSer: 3.878 ± 1.137
3.717TyrThr: 3.717 ± 0.561
1.131TyrVal: 1.131 ± 0.425
0.162TyrTrp: 0.162 ± 0.105
1.778TyrTyr: 1.778 ± 0.549
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 9 proteins (6189 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski