Amino acid dipepetide frequency for Desulfosporosinus youngiae DSM 17734

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.444AlaAla: 7.444 ± 0.093	0.949AlaCys: 0.949 ± 0.025	3.962AlaAsp: 3.962 ± 0.055	5.525AlaGlu: 5.525 ± 0.072	3.076AlaPhe: 3.076 ± 0.047	6.526AlaGly: 6.526 ± 0.085	1.319AlaHis: 1.319 ± 0.033	5.443AlaIle: 5.443 ± 0.064	4.845AlaLys: 4.845 ± 0.068	8.784AlaLeu: 8.784 ± 0.094	2.193AlaMet: 2.193 ± 0.044	2.806AlaAsn: 2.806 ± 0.055	2.35AlaPro: 2.35 ± 0.049	3.105AlaGln: 3.105 ± 0.054	3.628AlaArg: 3.628 ± 0.054	4.141AlaSer: 4.141 ± 0.058	3.535AlaThr: 3.535 ± 0.121	6.043AlaVal: 6.043 ± 0.068	0.776AlaTrp: 0.776 ± 0.026	2.387AlaTyr: 2.387 ± 0.048	0.0AlaXaa: 0.0 ± 0.0
Cys	0.785CysAla: 0.785 ± 0.022	0.204CysCys: 0.204 ± 0.012	0.523CysAsp: 0.523 ± 0.02	0.59CysGlu: 0.59 ± 0.018	0.473CysPhe: 0.473 ± 0.015	1.131CysGly: 1.131 ± 0.035	0.281CysHis: 0.281 ± 0.015	0.689CysIle: 0.689 ± 0.02	0.545CysLys: 0.545 ± 0.021	1.124CysLeu: 1.124 ± 0.028	0.28CysMet: 0.28 ± 0.014	0.401CysAsn: 0.401 ± 0.018	0.638CysPro: 0.638 ± 0.024	0.454CysGln: 0.454 ± 0.017	0.594CysArg: 0.594 ± 0.025	0.784CysSer: 0.784 ± 0.022	0.577CysThr: 0.577 ± 0.02	0.629CysVal: 0.629 ± 0.023	0.108CysTrp: 0.108 ± 0.009	0.349CysTyr: 0.349 ± 0.014	0.0CysXaa: 0.0 ± 0.0
Asp	3.407AspAla: 3.407 ± 0.065	0.532AspCys: 0.532 ± 0.018	2.169AspAsp: 2.169 ± 0.036	3.52AspGlu: 3.52 ± 0.053	2.313AspPhe: 2.313 ± 0.042	3.402AspGly: 3.402 ± 0.063	0.914AspHis: 0.914 ± 0.023	3.987AspIle: 3.987 ± 0.048	3.071AspLys: 3.071 ± 0.052	5.498AspLeu: 5.498 ± 0.068	1.314AspMet: 1.314 ± 0.03	1.92AspAsn: 1.92 ± 0.038	2.191AspPro: 2.191 ± 0.041	1.919AspGln: 1.919 ± 0.035	2.336AspArg: 2.336 ± 0.041	2.795AspSer: 2.795 ± 0.043	2.361AspThr: 2.361 ± 0.045	3.4AspVal: 3.4 ± 0.047	0.618AspTrp: 0.618 ± 0.023	2.133AspTyr: 2.133 ± 0.04	0.0AspXaa: 0.0 ± 0.0
Glu	5.315GluAla: 5.315 ± 0.071	0.62GluCys: 0.62 ± 0.018	3.389GluAsp: 3.389 ± 0.05	5.439GluGlu: 5.439 ± 0.07	2.553GluPhe: 2.553 ± 0.041	4.435GluGly: 4.435 ± 0.053	1.213GluHis: 1.213 ± 0.03	5.501GluIle: 5.501 ± 0.067	4.99GluLys: 4.99 ± 0.064	7.113GluLeu: 7.113 ± 0.078	1.94GluMet: 1.94 ± 0.033	3.033GluAsn: 3.033 ± 0.046	1.959GluPro: 1.959 ± 0.039	2.926GluGln: 2.926 ± 0.052	3.741GluArg: 3.741 ± 0.056	3.394GluSer: 3.394 ± 0.043	3.579GluThr: 3.579 ± 0.052	4.799GluVal: 4.799 ± 0.059	0.722GluTrp: 0.722 ± 0.024	2.034GluTyr: 2.034 ± 0.038	0.0GluXaa: 0.0 ± 0.0
Phe	3.113PheAla: 3.113 ± 0.049	0.538PheCys: 0.538 ± 0.019	2.037PheAsp: 2.037 ± 0.038	2.42PheGlu: 2.42 ± 0.039	1.77PhePhe: 1.77 ± 0.04	3.088PheGly: 3.088 ± 0.052	0.7PheHis: 0.7 ± 0.023	2.92PheIle: 2.92 ± 0.051	2.232PheLys: 2.232 ± 0.039	4.271PheLeu: 4.271 ± 0.069	1.086PheMet: 1.086 ± 0.027	1.678PheAsn: 1.678 ± 0.037	1.714PhePro: 1.714 ± 0.035	1.334PheGln: 1.334 ± 0.03	1.763PheArg: 1.763 ± 0.035	3.044PheSer: 3.044 ± 0.045	2.166PheThr: 2.166 ± 0.033	2.671PheVal: 2.671 ± 0.045	0.487PheTrp: 0.487 ± 0.018	1.484PheTyr: 1.484 ± 0.033	0.0PheXaa: 0.0 ± 0.0
Gly	5.597GlyAla: 5.597 ± 0.125	1.085GlyCys: 1.085 ± 0.027	3.34GlyAsp: 3.34 ± 0.058	4.702GlyGlu: 4.702 ± 0.061	3.263GlyPhe: 3.263 ± 0.051	5.41GlyGly: 5.41 ± 0.087	1.311GlyHis: 1.311 ± 0.028	6.347GlyIle: 6.347 ± 0.062	5.035GlyLys: 5.035 ± 0.055	7.717GlyLeu: 7.717 ± 0.083	2.243GlyMet: 2.243 ± 0.044	2.858GlyAsn: 2.858 ± 0.053	1.957GlyPro: 1.957 ± 0.039	2.7GlyGln: 2.7 ± 0.049	3.384GlyArg: 3.384 ± 0.049	4.313GlySer: 4.313 ± 0.057	4.275GlyThr: 4.275 ± 0.075	5.412GlyVal: 5.412 ± 0.058	0.84GlyTrp: 0.84 ± 0.023	2.812GlyTyr: 2.812 ± 0.044	0.0GlyXaa: 0.0 ± 0.0
His	1.146HisAla: 1.146 ± 0.029	0.275HisCys: 0.275 ± 0.015	0.891HisAsp: 0.891 ± 0.024	1.074HisGlu: 1.074 ± 0.028	0.795HisPhe: 0.795 ± 0.022	1.247HisGly: 1.247 ± 0.029	0.461HisHis: 0.461 ± 0.019	1.204HisIle: 1.204 ± 0.026	0.978HisLys: 0.978 ± 0.024	1.853HisLeu: 1.853 ± 0.04	0.437HisMet: 0.437 ± 0.017	0.716HisAsn: 0.716 ± 0.024	0.988HisPro: 0.988 ± 0.026	0.741HisGln: 0.741 ± 0.022	0.896HisArg: 0.896 ± 0.025	1.136HisSer: 1.136 ± 0.027	0.92HisThr: 0.92 ± 0.021	1.048HisVal: 1.048 ± 0.028	0.247HisTrp: 0.247 ± 0.012	0.744HisTyr: 0.744 ± 0.02	0.0HisXaa: 0.0 ± 0.0
Ile	6.121IleAla: 6.121 ± 0.068	0.799IleCys: 0.799 ± 0.022	3.723IleAsp: 3.723 ± 0.053	4.851IleGlu: 4.851 ± 0.053	2.812IlePhe: 2.812 ± 0.046	5.521IleGly: 5.521 ± 0.068	1.292IleHis: 1.292 ± 0.03	5.496IleIle: 5.496 ± 0.07	4.332IleLys: 4.332 ± 0.065	7.573IleLeu: 7.573 ± 0.078	1.82IleMet: 1.82 ± 0.037	3.133IleAsn: 3.133 ± 0.049	3.554IlePro: 3.554 ± 0.051	2.5IleGln: 2.5 ± 0.039	3.525IleArg: 3.525 ± 0.052	5.044IleSer: 5.044 ± 0.058	3.986IleThr: 3.986 ± 0.06	4.951IleVal: 4.951 ± 0.055	0.641IleTrp: 0.641 ± 0.022	2.258IleTyr: 2.258 ± 0.036	0.0IleXaa: 0.0 ± 0.0
Lys	5.022LysAla: 5.022 ± 0.063	0.553LysCys: 0.553 ± 0.02	3.374LysAsp: 3.374 ± 0.053	5.068LysGlu: 5.068 ± 0.057	1.857LysPhe: 1.857 ± 0.039	4.3LysGly: 4.3 ± 0.048	1.048LysHis: 1.048 ± 0.027	4.349LysIle: 4.349 ± 0.046	3.977LysLys: 3.977 ± 0.06	5.797LysLeu: 5.797 ± 0.069	1.745LysMet: 1.745 ± 0.038	2.803LysAsn: 2.803 ± 0.054	2.297LysPro: 2.297 ± 0.04	2.312LysGln: 2.312 ± 0.041	2.976LysArg: 2.976 ± 0.045	3.375LysSer: 3.375 ± 0.041	3.455LysThr: 3.455 ± 0.052	4.55LysVal: 4.55 ± 0.054	0.572LysTrp: 0.572 ± 0.022	1.88LysTyr: 1.88 ± 0.036	0.0LysXaa: 0.0 ± 0.0
Leu	8.941LeuAla: 8.941 ± 0.091	1.036LeuCys: 1.036 ± 0.027	5.343LeuAsp: 5.343 ± 0.063	7.011LeuGlu: 7.011 ± 0.083	4.106LeuPhe: 4.106 ± 0.064	7.79LeuGly: 7.79 ± 0.089	1.653LeuHis: 1.653 ± 0.027	7.266LeuIle: 7.266 ± 0.088	6.757LeuLys: 6.757 ± 0.076	10.541LeuLeu: 10.541 ± 0.116	2.687LeuMet: 2.687 ± 0.045	4.52LeuAsn: 4.52 ± 0.058	4.418LeuPro: 4.418 ± 0.062	3.637LeuGln: 3.637 ± 0.054	4.911LeuArg: 4.911 ± 0.066	7.145LeuSer: 7.145 ± 0.077	6.046LeuThr: 6.046 ± 0.07	6.724LeuVal: 6.724 ± 0.071	0.997LeuTrp: 0.997 ± 0.03	2.843LeuTyr: 2.843 ± 0.042	0.0LeuXaa: 0.0 ± 0.0
Met	2.358MetAla: 2.358 ± 0.039	0.211MetCys: 0.211 ± 0.013	1.502MetAsp: 1.502 ± 0.033	1.811MetGlu: 1.811 ± 0.032	0.934MetPhe: 0.934 ± 0.024	2.053MetGly: 2.053 ± 0.039	0.401MetHis: 0.401 ± 0.016	1.95MetIle: 1.95 ± 0.039	1.766MetLys: 1.766 ± 0.034	2.504MetLeu: 2.504 ± 0.046	0.71MetMet: 0.71 ± 0.021	1.255MetAsn: 1.255 ± 0.031	1.122MetPro: 1.122 ± 0.032	0.865MetGln: 0.865 ± 0.023	1.232MetArg: 1.232 ± 0.029	1.668MetSer: 1.668 ± 0.031	1.515MetThr: 1.515 ± 0.026	1.885MetVal: 1.885 ± 0.035	0.186MetTrp: 0.186 ± 0.01	0.652MetTyr: 0.652 ± 0.02	0.0MetXaa: 0.0 ± 0.0
Asn	2.789AsnAla: 2.789 ± 0.046	0.502AsnCys: 0.502 ± 0.018	1.902AsnAsp: 1.902 ± 0.036	2.464AsnGlu: 2.464 ± 0.043	1.55AsnPhe: 1.55 ± 0.038	2.873AsnGly: 2.873 ± 0.053	0.804AsnHis: 0.804 ± 0.024	2.956AsnIle: 2.956 ± 0.04	2.407AsnLys: 2.407 ± 0.045	4.378AsnLeu: 4.378 ± 0.066	0.992AsnMet: 0.992 ± 0.027	1.809AsnAsn: 1.809 ± 0.039	2.365AsnPro: 2.365 ± 0.043	1.691AsnGln: 1.691 ± 0.037	1.991AsnArg: 1.991 ± 0.041	2.585AsnSer: 2.585 ± 0.048	2.101AsnThr: 2.101 ± 0.04	2.714AsnVal: 2.714 ± 0.051	0.473AsnTrp: 0.473 ± 0.016	1.689AsnTyr: 1.689 ± 0.04	0.0AsnXaa: 0.0 ± 0.0
Pro	2.963ProAla: 2.963 ± 0.051	0.363ProCys: 0.363 ± 0.016	2.329ProAsp: 2.329 ± 0.039	3.427ProGlu: 3.427 ± 0.049	1.673ProPhe: 1.673 ± 0.034	3.04ProGly: 3.04 ± 0.048	0.722ProHis: 0.722 ± 0.026	2.656ProIle: 2.656 ± 0.041	2.2ProLys: 2.2 ± 0.041	3.987ProLeu: 3.987 ± 0.059	0.903ProMet: 0.903 ± 0.022	1.506ProAsn: 1.506 ± 0.035	1.348ProPro: 1.348 ± 0.04	1.53ProGln: 1.53 ± 0.035	1.491ProArg: 1.491 ± 0.042	2.353ProSer: 2.353 ± 0.042	1.921ProThr: 1.921 ± 0.043	3.153ProVal: 3.153 ± 0.047	0.465ProTrp: 0.465 ± 0.02	1.323ProTyr: 1.323 ± 0.031	0.0ProXaa: 0.0 ± 0.0
Gln	3.449GlnAla: 3.449 ± 0.057	0.314GlnCys: 0.314 ± 0.016	1.729GlnAsp: 1.729 ± 0.036	3.03GlnGlu: 3.03 ± 0.044	1.298GlnPhe: 1.298 ± 0.027	2.831GlnGly: 2.831 ± 0.056	0.587GlnHis: 0.587 ± 0.018	2.78GlnIle: 2.78 ± 0.047	2.395GlnLys: 2.395 ± 0.042	3.475GlnLeu: 3.475 ± 0.053	1.027GlnMet: 1.027 ± 0.027	1.514GlnAsn: 1.514 ± 0.032	1.275GlnPro: 1.275 ± 0.034	1.41GlnGln: 1.41 ± 0.036	1.922GlnArg: 1.922 ± 0.039	2.094GlnSer: 2.094 ± 0.04	2.11GlnThr: 2.11 ± 0.037	2.703GlnVal: 2.703 ± 0.045	0.438GlnTrp: 0.438 ± 0.019	1.11GlnTyr: 1.11 ± 0.025	0.0GlnXaa: 0.0 ± 0.0
Arg	3.115ArgAla: 3.115 ± 0.048	0.519ArgCys: 0.519 ± 0.02	2.335ArgAsp: 2.335 ± 0.043	3.746ArgGlu: 3.746 ± 0.052	2.033ArgPhe: 2.033 ± 0.035	2.934ArgGly: 2.934 ± 0.037	0.889ArgHis: 0.889 ± 0.026	3.656ArgIle: 3.656 ± 0.05	3.101ArgLys: 3.101 ± 0.052	5.133ArgLeu: 5.133 ± 0.064	1.335ArgMet: 1.335 ± 0.03	1.949ArgAsn: 1.949 ± 0.038	1.63ArgPro: 1.63 ± 0.037	1.998ArgGln: 1.998 ± 0.041	2.518ArgArg: 2.518 ± 0.049	2.576ArgSer: 2.576 ± 0.042	2.35ArgThr: 2.35 ± 0.042	3.349ArgVal: 3.349 ± 0.049	0.55ArgTrp: 0.55 ± 0.022	1.68ArgTyr: 1.68 ± 0.032	0.0ArgXaa: 0.0 ± 0.0
Ser	4.624SerAla: 4.624 ± 0.063	0.696SerCys: 0.696 ± 0.023	2.89SerAsp: 2.89 ± 0.045	3.781SerGlu: 3.781 ± 0.053	2.754SerPhe: 2.754 ± 0.05	5.219SerGly: 5.219 ± 0.069	1.117SerHis: 1.117 ± 0.027	4.436SerIle: 4.436 ± 0.061	3.438SerLys: 3.438 ± 0.05	6.692SerLeu: 6.692 ± 0.073	1.642SerMet: 1.642 ± 0.032	2.243SerAsn: 2.243 ± 0.043	2.478SerPro: 2.478 ± 0.038	2.266SerGln: 2.266 ± 0.04	2.798SerArg: 2.798 ± 0.043	3.983SerSer: 3.983 ± 0.059	2.92SerThr: 2.92 ± 0.055	4.077SerVal: 4.077 ± 0.052	0.695SerTrp: 0.695 ± 0.022	2.012SerTyr: 2.012 ± 0.04	0.0SerXaa: 0.0 ± 0.0
Thr	4.332ThrAla: 4.332 ± 0.076	0.549ThrCys: 0.549 ± 0.023	2.593ThrAsp: 2.593 ± 0.05	3.137ThrGlu: 3.137 ± 0.051	2.156ThrPhe: 2.156 ± 0.047	4.75ThrGly: 4.75 ± 0.138	0.976ThrHis: 0.976 ± 0.027	4.023ThrIle: 4.023 ± 0.061	2.778ThrLys: 2.778 ± 0.046	5.592ThrLeu: 5.592 ± 0.063	1.336ThrMet: 1.336 ± 0.032	2.083ThrAsn: 2.083 ± 0.043	2.458ThrPro: 2.458 ± 0.047	1.791ThrGln: 1.791 ± 0.036	2.101ThrArg: 2.101 ± 0.036	2.984ThrSer: 2.984 ± 0.057	2.867ThrThr: 2.867 ± 0.061	4.079ThrVal: 4.079 ± 0.07	0.518ThrTrp: 0.518 ± 0.018	1.731ThrTyr: 1.731 ± 0.043	0.0ThrXaa: 0.0 ± 0.0
Val	5.217ValAla: 5.217 ± 0.071	0.862ValCys: 0.862 ± 0.023	3.492ValAsp: 3.492 ± 0.052	4.401ValGlu: 4.401 ± 0.061	3.122ValPhe: 3.122 ± 0.041	4.724ValGly: 4.724 ± 0.064	1.232ValHis: 1.232 ± 0.026	5.467ValIle: 5.467 ± 0.063	4.109ValLys: 4.109 ± 0.054	7.531ValLeu: 7.531 ± 0.079	1.899ValMet: 1.899 ± 0.036	2.961ValAsn: 2.961 ± 0.043	2.772ValPro: 2.772 ± 0.041	2.395ValGln: 2.395 ± 0.045	3.286ValArg: 3.286 ± 0.05	4.694ValSer: 4.694 ± 0.054	3.899ValThr: 3.899 ± 0.075	5.147ValVal: 5.147 ± 0.078	0.683ValTrp: 0.683 ± 0.022	2.178ValTyr: 2.178 ± 0.043	0.0ValXaa: 0.0 ± 0.0
Trp	0.726TrpAla: 0.726 ± 0.024	0.107TrpCys: 0.107 ± 0.007	0.535TrpAsp: 0.535 ± 0.02	0.719TrpGlu: 0.719 ± 0.021	0.424TrpPhe: 0.424 ± 0.019	0.831TrpGly: 0.831 ± 0.025	0.207TrpHis: 0.207 ± 0.012	0.694TrpIle: 0.694 ± 0.02	0.622TrpLys: 0.622 ± 0.02	1.212TrpLeu: 1.212 ± 0.031	0.288TrpMet: 0.288 ± 0.014	0.484TrpAsn: 0.484 ± 0.017	0.384TrpPro: 0.384 ± 0.015	0.518TrpGln: 0.518 ± 0.019	0.524TrpArg: 0.524 ± 0.02	0.629TrpSer: 0.629 ± 0.02	0.495TrpThr: 0.495 ± 0.023	0.716TrpVal: 0.716 ± 0.024	0.152TrpTrp: 0.152 ± 0.009	0.292TrpTyr: 0.292 ± 0.012	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.372TyrAla: 2.372 ± 0.041	0.447TyrCys: 0.447 ± 0.018	1.743TyrAsp: 1.743 ± 0.044	1.975TyrGlu: 1.975 ± 0.043	1.555TyrPhe: 1.555 ± 0.035	2.494TyrGly: 2.494 ± 0.041	0.671TyrHis: 0.671 ± 0.021	2.11TyrIle: 2.11 ± 0.035	1.734TyrLys: 1.734 ± 0.036	3.596TyrLeu: 3.596 ± 0.054	0.703TyrMet: 0.703 ± 0.022	1.363TyrAsn: 1.363 ± 0.035	1.455TyrPro: 1.455 ± 0.033	1.4TyrGln: 1.4 ± 0.032	1.779TyrArg: 1.779 ± 0.036	2.026TyrSer: 2.026 ± 0.043	1.754TyrThr: 1.754 ± 0.042	2.021TyrVal: 2.021 ± 0.039	0.39TyrTrp: 0.39 ± 0.014	1.315TyrTyr: 1.315 ± 0.03	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 5108 proteins (1565203 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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