Amino acid dipepetide frequency for Penicillium stoloniferum virus S

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.202AlaAla: 7.202 ± 4.202
2.058AlaCys: 2.058 ± 0.158
3.086AlaAsp: 3.086 ± 2.426
3.086AlaGlu: 3.086 ± 0.493
7.202AlaPhe: 7.202 ± 0.178
6.173AlaGly: 6.173 ± 1.933
2.058AlaHis: 2.058 ± 1.618
2.058AlaIle: 2.058 ± 1.302
3.086AlaLys: 3.086 ± 0.493
6.173AlaLeu: 6.173 ± 1.933
1.029AlaMet: 1.029 ± 0.651
0.0AlaAsn: 0.0 ± 0.0
6.173AlaPro: 6.173 ± 1.933
4.115AlaGln: 4.115 ± 1.775
4.115AlaArg: 4.115 ± 0.315
10.288AlaSer: 10.288 ± 2.248
3.086AlaThr: 3.086 ± 2.426
5.144AlaVal: 5.144 ± 2.584
3.086AlaTrp: 3.086 ± 0.493
2.058AlaTyr: 2.058 ± 0.158
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
1.029CysAsp: 1.029 ± 0.651
2.058CysGlu: 2.058 ± 1.302
2.058CysPhe: 2.058 ± 0.158
1.029CysGly: 1.029 ± 0.651
0.0CysHis: 0.0 ± 0.0
1.029CysIle: 1.029 ± 0.809
0.0CysLys: 0.0 ± 0.0
1.029CysLeu: 1.029 ± 0.651
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
1.029CysPro: 1.029 ± 0.651
3.086CysGln: 3.086 ± 0.493
0.0CysArg: 0.0 ± 0.0
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
1.029CysVal: 1.029 ± 0.651
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
5.144AspAla: 5.144 ± 0.336
0.0AspCys: 0.0 ± 0.0
4.115AspAsp: 4.115 ± 2.604
0.0AspGlu: 0.0 ± 0.0
3.086AspPhe: 3.086 ± 0.966
5.144AspGly: 5.144 ± 0.336
0.0AspHis: 0.0 ± 0.0
2.058AspIle: 2.058 ± 1.302
1.029AspLys: 1.029 ± 0.809
4.115AspLeu: 4.115 ± 1.775
0.0AspMet: 0.0 ± 0.0
0.0AspAsn: 0.0 ± 0.0
7.202AspPro: 7.202 ± 3.098
3.086AspGln: 3.086 ± 0.966
3.086AspArg: 3.086 ± 0.966
7.202AspSer: 7.202 ± 3.098
3.086AspThr: 3.086 ± 0.493
5.144AspVal: 5.144 ± 1.124
2.058AspTrp: 2.058 ± 0.158
2.058AspTyr: 2.058 ± 0.158
0.0AspXaa: 0.0 ± 0.0
Glu
3.086GluAla: 3.086 ± 0.493
1.029GluCys: 1.029 ± 0.651
2.058GluAsp: 2.058 ± 0.158
2.058GluGlu: 2.058 ± 1.302
8.23GluPhe: 8.23 ± 5.01
4.115GluGly: 4.115 ± 1.144
1.029GluHis: 1.029 ± 0.809
3.086GluIle: 3.086 ± 1.953
4.115GluLys: 4.115 ± 2.604
2.058GluLeu: 2.058 ± 1.618
3.086GluMet: 3.086 ± 1.953
0.0GluAsn: 0.0 ± 0.0
2.058GluPro: 2.058 ± 0.158
1.029GluGln: 1.029 ± 0.809
1.029GluArg: 1.029 ± 0.809
2.058GluSer: 2.058 ± 1.302
1.029GluThr: 1.029 ± 0.651
2.058GluVal: 2.058 ± 0.158
2.058GluTrp: 2.058 ± 1.302
1.029GluTyr: 1.029 ± 0.651
0.0GluXaa: 0.0 ± 0.0
Phe
5.144PheAla: 5.144 ± 2.584
2.058PheCys: 2.058 ± 0.158
7.202PheAsp: 7.202 ± 3.098
1.029PheGlu: 1.029 ± 0.809
1.029PhePhe: 1.029 ± 0.809
3.086PheGly: 3.086 ± 2.426
0.0PheHis: 0.0 ± 0.0
2.058PheIle: 2.058 ± 0.158
5.144PheLys: 5.144 ± 0.336
4.115PheLeu: 4.115 ± 3.235
2.058PheMet: 2.058 ± 1.302
0.0PheAsn: 0.0 ± 0.0
4.115PhePro: 4.115 ± 0.315
0.0PheGln: 0.0 ± 0.0
5.144PheArg: 5.144 ± 1.796
8.23PheSer: 8.23 ± 0.829
6.173PheThr: 6.173 ± 1.933
1.029PheVal: 1.029 ± 0.809
1.029PheTrp: 1.029 ± 0.651
2.058PheTyr: 2.058 ± 1.302
0.0PheXaa: 0.0 ± 0.0
Gly
3.086GlyAla: 3.086 ± 0.493
0.0GlyCys: 0.0 ± 0.0
5.144GlyAsp: 5.144 ± 1.124
5.144GlyGlu: 5.144 ± 1.124
2.058GlyPhe: 2.058 ± 1.302
7.202GlyGly: 7.202 ± 0.178
2.058GlyHis: 2.058 ± 0.158
2.058GlyIle: 2.058 ± 0.158
7.202GlyLys: 7.202 ± 1.282
7.202GlyLeu: 7.202 ± 0.178
3.086GlyMet: 3.086 ± 2.307
2.058GlyAsn: 2.058 ± 1.618
0.0GlyPro: 0.0 ± 0.0
5.144GlyGln: 5.144 ± 0.336
4.115GlyArg: 4.115 ± 2.604
6.173GlySer: 6.173 ± 1.933
4.115GlyThr: 4.115 ± 0.315
5.144GlyVal: 5.144 ± 1.124
2.058GlyTrp: 2.058 ± 1.302
2.058GlyTyr: 2.058 ± 1.302
0.0GlyXaa: 0.0 ± 0.0
His
4.115HisAla: 4.115 ± 1.775
0.0HisCys: 0.0 ± 0.0
1.029HisAsp: 1.029 ± 0.651
2.058HisGlu: 2.058 ± 1.302
1.029HisPhe: 1.029 ± 0.651
0.0HisGly: 0.0 ± 0.0
1.029HisHis: 1.029 ± 0.809
1.029HisIle: 1.029 ± 0.809
1.029HisLys: 1.029 ± 0.809
3.086HisLeu: 3.086 ± 0.966
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
1.029HisPro: 1.029 ± 0.651
0.0HisGln: 0.0 ± 0.0
2.058HisArg: 2.058 ± 1.302
1.029HisSer: 1.029 ± 0.809
0.0HisThr: 0.0 ± 0.0
1.029HisVal: 1.029 ± 0.809
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
2.058IleAla: 2.058 ± 0.158
0.0IleCys: 0.0 ± 0.0
1.029IleAsp: 1.029 ± 0.651
1.029IleGlu: 1.029 ± 0.651
3.086IlePhe: 3.086 ± 0.966
3.086IleGly: 3.086 ± 0.493
0.0IleHis: 0.0 ± 0.0
1.029IleIle: 1.029 ± 0.651
0.0IleLys: 0.0 ± 0.0
5.144IleLeu: 5.144 ± 1.796
0.0IleMet: 0.0 ± 0.0
2.058IleAsn: 2.058 ± 1.302
1.029IlePro: 1.029 ± 0.809
0.0IleGln: 0.0 ± 0.0
4.115IleArg: 4.115 ± 2.604
3.086IleSer: 3.086 ± 0.493
1.029IleThr: 1.029 ± 0.809
1.029IleVal: 1.029 ± 0.809
0.0IleTrp: 0.0 ± 0.0
3.086IleTyr: 3.086 ± 1.953
0.0IleXaa: 0.0 ± 0.0
Lys
6.173LysAla: 6.173 ± 0.473
1.029LysCys: 1.029 ± 0.651
3.086LysAsp: 3.086 ± 0.493
1.029LysGlu: 1.029 ± 0.651
3.086LysPhe: 3.086 ± 1.953
1.029LysGly: 1.029 ± 0.651
0.0LysHis: 0.0 ± 0.0
0.0LysIle: 0.0 ± 0.0
2.058LysLys: 2.058 ± 1.302
4.115LysLeu: 4.115 ± 1.144
1.029LysMet: 1.029 ± 0.651
1.029LysAsn: 1.029 ± 0.651
2.058LysPro: 2.058 ± 1.618
2.058LysGln: 2.058 ± 0.158
4.115LysArg: 4.115 ± 0.315
3.086LysSer: 3.086 ± 0.493
3.086LysThr: 3.086 ± 0.493
2.058LysVal: 2.058 ± 1.302
1.029LysTrp: 1.029 ± 0.651
3.086LysTyr: 3.086 ± 0.966
0.0LysXaa: 0.0 ± 0.0
Leu
14.403LeuAla: 14.403 ± 4.024
0.0LeuCys: 0.0 ± 0.0
4.115LeuAsp: 4.115 ± 2.604
2.058LeuGlu: 2.058 ± 1.618
3.086LeuPhe: 3.086 ± 0.966
7.202LeuGly: 7.202 ± 0.178
1.029LeuHis: 1.029 ± 0.651
2.058LeuIle: 2.058 ± 1.302
3.086LeuLys: 3.086 ± 0.493
7.202LeuLeu: 7.202 ± 1.282
1.029LeuMet: 1.029 ± 0.651
3.086LeuAsn: 3.086 ± 0.493
6.173LeuPro: 6.173 ± 3.393
2.058LeuGln: 2.058 ± 1.302
6.173LeuArg: 6.173 ± 0.987
7.202LeuSer: 7.202 ± 4.202
3.086LeuThr: 3.086 ± 0.966
4.115LeuVal: 4.115 ± 1.144
2.058LeuTrp: 2.058 ± 0.158
3.086LeuTyr: 3.086 ± 1.953
0.0LeuXaa: 0.0 ± 0.0
Met
0.0MetAla: 0.0 ± 0.0
0.0MetCys: 0.0 ± 0.0
2.058MetAsp: 2.058 ± 0.158
3.086MetGlu: 3.086 ± 1.953
2.058MetPhe: 2.058 ± 1.302
2.058MetGly: 2.058 ± 0.158
0.0MetHis: 0.0 ± 0.0
3.086MetIle: 3.086 ± 1.953
1.029MetLys: 1.029 ± 0.651
3.086MetLeu: 3.086 ± 1.953
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
2.058MetPro: 2.058 ± 0.158
0.0MetGln: 0.0 ± 0.0
1.029MetArg: 1.029 ± 0.651
3.086MetSer: 3.086 ± 0.966
0.0MetThr: 0.0 ± 0.0
2.058MetVal: 2.058 ± 0.158
0.0MetTrp: 0.0 ± 0.0
2.058MetTyr: 2.058 ± 1.302
0.0MetXaa: 0.0 ± 0.0
Asn
1.029AsnAla: 1.029 ± 0.651
0.0AsnCys: 0.0 ± 0.0
1.029AsnAsp: 1.029 ± 0.809
1.029AsnGlu: 1.029 ± 0.651
1.029AsnPhe: 1.029 ± 0.809
4.115AsnGly: 4.115 ± 1.144
0.0AsnHis: 0.0 ± 0.0
1.029AsnIle: 1.029 ± 0.651
0.0AsnLys: 0.0 ± 0.0
0.0AsnLeu: 0.0 ± 0.0
2.058AsnMet: 2.058 ± 0.158
1.029AsnAsn: 1.029 ± 0.809
1.029AsnPro: 1.029 ± 0.809
1.029AsnGln: 1.029 ± 0.809
2.058AsnArg: 2.058 ± 1.302
3.086AsnSer: 3.086 ± 0.966
2.058AsnThr: 2.058 ± 1.302
1.029AsnVal: 1.029 ± 0.651
1.029AsnTrp: 1.029 ± 0.809
1.029AsnTyr: 1.029 ± 0.651
0.0AsnXaa: 0.0 ± 0.0
Pro
3.086ProAla: 3.086 ± 0.493
2.058ProCys: 2.058 ± 1.302
1.029ProAsp: 1.029 ± 0.651
5.144ProGlu: 5.144 ± 0.336
2.058ProPhe: 2.058 ± 1.302
4.115ProGly: 4.115 ± 1.775
1.029ProHis: 1.029 ± 0.651
1.029ProIle: 1.029 ± 0.651
1.029ProLys: 1.029 ± 0.651
6.173ProLeu: 6.173 ± 0.473
3.086ProMet: 3.086 ± 0.966
0.0ProAsn: 0.0 ± 0.0
2.058ProPro: 2.058 ± 0.158
1.029ProGln: 1.029 ± 0.651
2.058ProArg: 2.058 ± 0.158
8.23ProSer: 8.23 ± 0.631
6.173ProThr: 6.173 ± 0.473
3.086ProVal: 3.086 ± 2.426
1.029ProTrp: 1.029 ± 0.809
1.029ProTyr: 1.029 ± 0.651
0.0ProXaa: 0.0 ± 0.0
Gln
2.058GlnAla: 2.058 ± 1.618
1.029GlnCys: 1.029 ± 0.651
0.0GlnAsp: 0.0 ± 0.0
2.058GlnGlu: 2.058 ± 0.158
4.115GlnPhe: 4.115 ± 1.775
1.029GlnGly: 1.029 ± 0.809
0.0GlnHis: 0.0 ± 0.0
0.0GlnIle: 0.0 ± 0.0
2.058GlnLys: 2.058 ± 1.302
2.058GlnLeu: 2.058 ± 1.618
3.086GlnMet: 3.086 ± 0.966
2.058GlnAsn: 2.058 ± 1.302
0.0GlnPro: 0.0 ± 0.0
3.086GlnGln: 3.086 ± 0.966
7.202GlnArg: 7.202 ± 1.638
2.058GlnSer: 2.058 ± 0.158
1.029GlnThr: 1.029 ± 0.651
4.115GlnVal: 4.115 ± 0.315
0.0GlnTrp: 0.0 ± 0.0
1.029GlnTyr: 1.029 ± 0.809
0.0GlnXaa: 0.0 ± 0.0
Arg
4.115ArgAla: 4.115 ± 0.315
0.0ArgCys: 0.0 ± 0.0
6.173ArgAsp: 6.173 ± 0.473
4.115ArgGlu: 4.115 ± 1.144
5.144ArgPhe: 5.144 ± 1.124
5.144ArgGly: 5.144 ± 3.255
1.029ArgHis: 1.029 ± 0.651
1.029ArgIle: 1.029 ± 0.809
2.058ArgLys: 2.058 ± 1.302
5.144ArgLeu: 5.144 ± 0.336
3.086ArgMet: 3.086 ± 0.971
3.086ArgAsn: 3.086 ± 0.493
2.058ArgPro: 2.058 ± 1.302
3.086ArgGln: 3.086 ± 0.966
6.173ArgArg: 6.173 ± 0.473
7.202ArgSer: 7.202 ± 0.178
2.058ArgThr: 2.058 ± 1.302
5.144ArgVal: 5.144 ± 0.336
3.086ArgTrp: 3.086 ± 1.953
2.058ArgTyr: 2.058 ± 0.158
0.0ArgXaa: 0.0 ± 0.0
Ser
11.317SerAla: 11.317 ± 5.977
2.058SerCys: 2.058 ± 0.158
5.144SerAsp: 5.144 ± 2.584
4.115SerGlu: 4.115 ± 1.144
4.115SerPhe: 4.115 ± 2.604
6.173SerGly: 6.173 ± 0.473
4.115SerHis: 4.115 ± 0.315
4.115SerIle: 4.115 ± 1.775
6.173SerLys: 6.173 ± 0.987
8.23SerLeu: 8.23 ± 0.829
1.029SerMet: 1.029 ± 0.651
3.086SerAsn: 3.086 ± 0.493
6.173SerPro: 6.173 ± 0.987
3.086SerGln: 3.086 ± 0.966
3.086SerArg: 3.086 ± 0.966
10.288SerSer: 10.288 ± 5.168
2.058SerThr: 2.058 ± 1.618
9.259SerVal: 9.259 ± 1.44
2.058SerTrp: 2.058 ± 0.158
2.058SerTyr: 2.058 ± 0.158
0.0SerXaa: 0.0 ± 0.0
Thr
2.058ThrAla: 2.058 ± 0.158
2.058ThrCys: 2.058 ± 1.302
3.086ThrAsp: 3.086 ± 0.966
3.086ThrGlu: 3.086 ± 0.966
1.029ThrPhe: 1.029 ± 0.809
3.086ThrGly: 3.086 ± 0.966
1.029ThrHis: 1.029 ± 0.809
1.029ThrIle: 1.029 ± 0.809
4.115ThrLys: 4.115 ± 1.144
3.086ThrLeu: 3.086 ± 1.953
0.0ThrMet: 0.0 ± 0.0
2.058ThrAsn: 2.058 ± 0.158
2.058ThrPro: 2.058 ± 1.302
2.058ThrGln: 2.058 ± 0.158
8.23ThrArg: 8.23 ± 0.631
3.086ThrSer: 3.086 ± 0.966
6.173ThrThr: 6.173 ± 0.473
2.058ThrVal: 2.058 ± 1.618
1.029ThrTrp: 1.029 ± 0.809
1.029ThrTyr: 1.029 ± 0.651
0.0ThrXaa: 0.0 ± 0.0
Val
3.086ValAla: 3.086 ± 0.493
0.0ValCys: 0.0 ± 0.0
4.115ValAsp: 4.115 ± 0.315
2.058ValGlu: 2.058 ± 0.158
3.086ValPhe: 3.086 ± 2.426
5.144ValGly: 5.144 ± 2.584
2.058ValHis: 2.058 ± 1.618
0.0ValIle: 0.0 ± 0.0
1.029ValLys: 1.029 ± 0.809
5.144ValLeu: 5.144 ± 2.584
1.029ValMet: 1.029 ± 0.651
4.115ValAsn: 4.115 ± 0.315
5.144ValPro: 5.144 ± 0.336
1.029ValGln: 1.029 ± 0.651
1.029ValArg: 1.029 ± 0.809
8.23ValSer: 8.23 ± 2.091
2.058ValThr: 2.058 ± 1.618
8.23ValVal: 8.23 ± 2.091
3.086ValTrp: 3.086 ± 1.953
4.115ValTyr: 4.115 ± 2.604
0.0ValXaa: 0.0 ± 0.0
Trp
1.029TrpAla: 1.029 ± 0.809
0.0TrpCys: 0.0 ± 0.0
2.058TrpAsp: 2.058 ± 1.302
1.029TrpGlu: 1.029 ± 0.809
3.086TrpPhe: 3.086 ± 1.953
0.0TrpGly: 0.0 ± 0.0
1.029TrpHis: 1.029 ± 0.651
3.086TrpIle: 3.086 ± 1.953
0.0TrpLys: 0.0 ± 0.0
4.115TrpLeu: 4.115 ± 1.144
0.0TrpMet: 0.0 ± 0.0
1.029TrpAsn: 1.029 ± 0.809
0.0TrpPro: 0.0 ± 0.0
1.029TrpGln: 1.029 ± 0.809
3.086TrpArg: 3.086 ± 0.493
0.0TrpSer: 0.0 ± 0.0
3.086TrpThr: 3.086 ± 0.493
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
1.029TrpTyr: 1.029 ± 0.651
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.086TyrAla: 3.086 ± 0.966
0.0TyrCys: 0.0 ± 0.0
1.029TyrAsp: 1.029 ± 0.651
1.029TyrGlu: 1.029 ± 0.809
1.029TyrPhe: 1.029 ± 0.651
7.202TyrGly: 7.202 ± 4.558
2.058TyrHis: 2.058 ± 1.302
1.029TyrIle: 1.029 ± 0.651
0.0TyrLys: 0.0 ± 0.0
1.029TyrLeu: 1.029 ± 0.651
1.029TyrMet: 1.029 ± 0.651
0.0TyrAsn: 0.0 ± 0.0
3.086TyrPro: 3.086 ± 0.493
2.058TyrGln: 2.058 ± 1.302
3.086TyrArg: 3.086 ± 0.493
4.115TyrSer: 4.115 ± 0.315
2.058TyrThr: 2.058 ± 1.302
1.029TyrVal: 1.029 ± 0.651
0.0TyrTrp: 0.0 ± 0.0
1.029TyrTyr: 1.029 ± 0.651
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (973 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski