Amino acid dipepetide frequency for Beihai weivirus-like virus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
16.508AlaAla: 16.508 ± 4.737
1.905AlaCys: 1.905 ± 0.526
4.444AlaAsp: 4.444 ± 0.428
6.349AlaGlu: 6.349 ± 1.72
3.175AlaPhe: 3.175 ± 0.991
7.619AlaGly: 7.619 ± 1.918
1.27AlaHis: 1.27 ± 0.52
5.714AlaIle: 5.714 ± 1.681
2.54AlaLys: 2.54 ± 0.712
6.349AlaLeu: 6.349 ± 1.905
2.54AlaMet: 2.54 ± 0.712
1.905AlaAsn: 1.905 ± 0.626
5.714AlaPro: 5.714 ± 1.293
3.175AlaGln: 3.175 ± 0.991
9.524AlaArg: 9.524 ± 4.419
6.349AlaSer: 6.349 ± 0.96
5.714AlaThr: 5.714 ± 2.003
3.81AlaVal: 3.81 ± 0.309
2.54AlaTrp: 2.54 ± 0.758
3.175AlaTyr: 3.175 ± 0.131
0.0AlaXaa: 0.0 ± 0.0
Cys
0.635CysAla: 0.635 ± 0.334
0.0CysCys: 0.0 ± 0.0
0.635CysAsp: 0.635 ± 0.834
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
2.54CysGly: 2.54 ± 0.403
0.635CysHis: 0.635 ± 0.334
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
1.27CysLeu: 1.27 ± 0.669
1.905CysMet: 1.905 ± 0.626
1.27CysAsn: 1.27 ± 0.52
0.635CysPro: 0.635 ± 0.698
0.635CysGln: 0.635 ± 0.334
0.635CysArg: 0.635 ± 0.334
2.54CysSer: 2.54 ± 0.403
0.635CysThr: 0.635 ± 0.334
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
4.444AspAla: 4.444 ± 3.266
0.635AspCys: 0.635 ± 0.334
3.81AspAsp: 3.81 ± 2.027
3.175AspGlu: 3.175 ± 1.2
3.81AspPhe: 3.81 ± 1.27
8.889AspGly: 8.889 ± 2.699
2.54AspHis: 2.54 ± 1.314
1.27AspIle: 1.27 ± 1.06
0.0AspLys: 0.0 ± 0.0
4.444AspLeu: 4.444 ± 1.57
1.27AspMet: 1.27 ± 0.669
1.27AspAsn: 1.27 ± 0.657
3.175AspPro: 3.175 ± 1.69
0.635AspGln: 0.635 ± 0.334
5.079AspArg: 5.079 ± 1.882
2.54AspSer: 2.54 ± 0.403
3.175AspThr: 3.175 ± 0.991
3.81AspVal: 3.81 ± 0.959
0.0AspTrp: 0.0 ± 0.0
0.0AspTyr: 0.0 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
6.349GluAla: 6.349 ± 2.241
0.0GluCys: 0.0 ± 0.0
7.619GluAsp: 7.619 ± 0.618
5.714GluGlu: 5.714 ± 3.009
1.905GluPhe: 1.905 ± 1.184
8.254GluGly: 8.254 ± 2.484
1.905GluHis: 1.905 ± 0.626
1.27GluIle: 1.27 ± 0.669
3.175GluLys: 3.175 ± 1.672
3.81GluLeu: 3.81 ± 1.28
1.905GluMet: 1.905 ± 1.003
2.54GluAsn: 2.54 ± 0.712
1.905GluPro: 1.905 ± 1.003
2.54GluGln: 2.54 ± 0.758
5.714GluArg: 5.714 ± 1.732
0.635GluSer: 0.635 ± 0.334
4.444GluThr: 4.444 ± 0.788
5.714GluVal: 5.714 ± 0.943
1.905GluTrp: 1.905 ± 0.526
1.27GluTyr: 1.27 ± 0.657
0.0GluXaa: 0.0 ± 0.0
Phe
3.81PheAla: 3.81 ± 1.28
0.635PheCys: 0.635 ± 0.698
2.54PheAsp: 2.54 ± 1.267
4.444PheGlu: 4.444 ± 1.594
0.635PhePhe: 0.635 ± 0.334
3.175PheGly: 3.175 ± 2.287
2.54PheHis: 2.54 ± 1.267
1.27PheIle: 1.27 ± 1.06
1.27PheLys: 1.27 ± 1.396
2.54PheLeu: 2.54 ± 0.712
0.635PheMet: 0.635 ± 0.445
0.635PheAsn: 0.635 ± 0.334
0.635PhePro: 0.635 ± 0.334
1.905PheGln: 1.905 ± 1.003
3.175PheArg: 3.175 ± 1.672
0.635PheSer: 0.635 ± 0.698
1.905PheThr: 1.905 ± 1.184
3.175PheVal: 3.175 ± 0.131
1.905PheTrp: 1.905 ± 1.003
0.635PheTyr: 0.635 ± 0.334
0.0PheXaa: 0.0 ± 0.0
Gly
8.889GlyAla: 8.889 ± 2.701
1.27GlyCys: 1.27 ± 0.657
5.079GlyAsp: 5.079 ± 1.516
7.619GlyGlu: 7.619 ± 4.055
2.54GlyPhe: 2.54 ± 0.758
8.254GlyGly: 8.254 ± 2.751
3.81GlyHis: 3.81 ± 3.109
3.175GlyIle: 3.175 ± 1.911
3.81GlyLys: 3.81 ± 1.052
7.619GlyLeu: 7.619 ± 0.618
2.54GlyMet: 2.54 ± 0.712
0.635GlyAsn: 0.635 ± 0.698
3.175GlyPro: 3.175 ± 0.131
6.349GlyGln: 6.349 ± 2.241
5.714GlyArg: 5.714 ± 1.446
8.889GlySer: 8.889 ± 1.577
3.175GlyThr: 3.175 ± 2.111
8.889GlyVal: 8.889 ± 2.547
2.54GlyTrp: 2.54 ± 0.758
1.905GlyTyr: 1.905 ± 1.003
0.0GlyXaa: 0.0 ± 0.0
His
2.54HisAla: 2.54 ± 1.478
0.0HisCys: 0.0 ± 0.0
3.175HisAsp: 3.175 ± 3.121
1.27HisGlu: 1.27 ± 0.669
1.27HisPhe: 1.27 ± 1.668
3.175HisGly: 3.175 ± 2.287
0.635HisHis: 0.635 ± 0.834
0.635HisIle: 0.635 ± 0.334
0.0HisLys: 0.0 ± 0.0
1.27HisLeu: 1.27 ± 0.52
1.27HisMet: 1.27 ± 0.52
0.635HisAsn: 0.635 ± 0.834
2.54HisPro: 2.54 ± 1.267
0.635HisGln: 0.635 ± 0.334
2.54HisArg: 2.54 ± 1.314
1.27HisSer: 1.27 ± 0.52
1.27HisThr: 1.27 ± 0.52
3.175HisVal: 3.175 ± 0.991
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
2.54IleAla: 2.54 ± 0.403
0.635IleCys: 0.635 ± 0.334
1.905IleAsp: 1.905 ± 1.003
5.714IleGlu: 5.714 ± 1.681
0.635IlePhe: 0.635 ± 0.698
4.444IleGly: 4.444 ± 1.492
0.0IleHis: 0.0 ± 0.0
1.27IleIle: 1.27 ± 0.669
2.54IleLys: 2.54 ± 0.712
1.27IleLeu: 1.27 ± 0.657
0.0IleMet: 0.0 ± 0.0
1.905IleAsn: 1.905 ± 0.526
2.54IlePro: 2.54 ± 1.478
0.0IleGln: 0.0 ± 0.0
3.81IleArg: 3.81 ± 1.28
0.635IleSer: 0.635 ± 0.334
4.444IleThr: 4.444 ± 1.207
1.27IleVal: 1.27 ± 1.06
0.635IleTrp: 0.635 ± 0.698
0.635IleTyr: 0.635 ± 0.334
0.0IleXaa: 0.0 ± 0.0
Lys
5.714LysAla: 5.714 ± 1.681
0.635LysCys: 0.635 ± 0.334
3.81LysAsp: 3.81 ± 1.28
1.905LysGlu: 1.905 ± 1.003
2.54LysPhe: 2.54 ± 0.712
1.905LysGly: 1.905 ± 1.003
1.905LysHis: 1.905 ± 1.003
1.905LysIle: 1.905 ± 1.003
6.984LysLys: 6.984 ± 2.016
3.81LysLeu: 3.81 ± 1.559
0.0LysMet: 0.0 ± 0.0
1.27LysAsn: 1.27 ± 0.669
3.175LysPro: 3.175 ± 0.991
1.905LysGln: 1.905 ± 1.003
3.81LysArg: 3.81 ± 1.28
0.635LysSer: 0.635 ± 0.334
1.905LysThr: 1.905 ± 1.184
1.27LysVal: 1.27 ± 0.669
1.27LysTrp: 1.27 ± 0.52
1.27LysTyr: 1.27 ± 0.669
0.0LysXaa: 0.0 ± 0.0
Leu
12.063LeuAla: 12.063 ± 1.241
0.635LeuCys: 0.635 ± 0.334
1.905LeuAsp: 1.905 ± 1.003
6.984LeuGlu: 6.984 ± 2.098
1.27LeuPhe: 1.27 ± 0.669
7.619LeuGly: 7.619 ± 0.361
1.27LeuHis: 1.27 ± 0.52
1.905LeuIle: 1.905 ± 1.003
3.175LeuLys: 3.175 ± 1.672
6.349LeuLeu: 6.349 ± 1.035
3.175LeuMet: 3.175 ± 0.918
2.54LeuAsn: 2.54 ± 1.039
5.079LeuPro: 5.079 ± 2.079
3.175LeuGln: 3.175 ± 0.131
3.175LeuArg: 3.175 ± 0.953
4.444LeuSer: 4.444 ± 0.788
3.81LeuThr: 3.81 ± 1.052
4.444LeuVal: 4.444 ± 0.788
1.905LeuTrp: 1.905 ± 0.526
0.635LeuTyr: 0.635 ± 0.334
0.0LeuXaa: 0.0 ± 0.0
Met
2.54MetAla: 2.54 ± 1.039
0.635MetCys: 0.635 ± 0.698
1.905MetAsp: 1.905 ± 1.003
0.635MetGlu: 0.635 ± 0.334
0.0MetPhe: 0.0 ± 0.0
3.175MetGly: 3.175 ± 0.953
0.635MetHis: 0.635 ± 0.334
1.27MetIle: 1.27 ± 0.52
2.54MetLys: 2.54 ± 0.712
4.444MetLeu: 4.444 ± 1.57
0.0MetMet: 0.0 ± 0.0
0.635MetAsn: 0.635 ± 0.698
3.175MetPro: 3.175 ± 0.98
0.635MetGln: 0.635 ± 0.698
0.635MetArg: 0.635 ± 0.334
0.635MetSer: 0.635 ± 0.334
1.27MetThr: 1.27 ± 0.52
1.905MetVal: 1.905 ± 0.626
0.635MetTrp: 0.635 ± 0.334
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.175AsnAla: 3.175 ± 1.69
0.0AsnCys: 0.0 ± 0.0
1.27AsnAsp: 1.27 ± 1.396
1.27AsnGlu: 1.27 ± 0.52
2.54AsnPhe: 2.54 ± 0.712
3.175AsnGly: 3.175 ± 0.131
0.0AsnHis: 0.0 ± 0.0
1.905AsnIle: 1.905 ± 0.626
0.635AsnLys: 0.635 ± 0.334
1.905AsnLeu: 1.905 ± 1.003
1.905AsnMet: 1.905 ± 1.184
0.635AsnAsn: 0.635 ± 0.698
1.905AsnPro: 1.905 ± 0.626
0.0AsnGln: 0.0 ± 0.0
0.635AsnArg: 0.635 ± 0.698
0.635AsnSer: 0.635 ± 0.334
0.635AsnThr: 0.635 ± 0.834
1.905AsnVal: 1.905 ± 1.003
0.635AsnTrp: 0.635 ± 0.334
0.635AsnTyr: 0.635 ± 0.334
0.0AsnXaa: 0.0 ± 0.0
Pro
7.619ProAla: 7.619 ± 1.21
0.635ProCys: 0.635 ± 0.834
3.175ProAsp: 3.175 ± 0.131
4.444ProGlu: 4.444 ± 2.34
1.27ProPhe: 1.27 ± 0.52
3.81ProGly: 3.81 ± 2.027
0.0ProHis: 0.0 ± 0.0
1.27ProIle: 1.27 ± 1.396
3.175ProLys: 3.175 ± 1.672
4.444ProLeu: 4.444 ± 3.055
0.0ProMet: 0.0 ± 0.0
1.27ProAsn: 1.27 ± 0.669
5.079ProPro: 5.079 ± 1.85
2.54ProGln: 2.54 ± 1.039
5.714ProArg: 5.714 ± 0.943
3.175ProSer: 3.175 ± 0.131
3.175ProThr: 3.175 ± 0.991
4.444ProVal: 4.444 ± 0.428
2.54ProTrp: 2.54 ± 0.758
1.27ProTyr: 1.27 ± 1.396
0.0ProXaa: 0.0 ± 0.0
Gln
4.444GlnAla: 4.444 ± 1.594
0.0GlnCys: 0.0 ± 0.0
1.905GlnAsp: 1.905 ± 0.526
3.81GlnGlu: 3.81 ± 2.006
1.905GlnPhe: 1.905 ± 0.729
4.444GlnGly: 4.444 ± 2.177
1.27GlnHis: 1.27 ± 0.657
0.0GlnIle: 0.0 ± 0.0
0.635GlnLys: 0.635 ± 0.698
0.635GlnLeu: 0.635 ± 0.698
0.0GlnMet: 0.0 ± 0.0
0.635GlnAsn: 0.635 ± 0.334
3.81GlnPro: 3.81 ± 1.252
1.905GlnGln: 1.905 ± 0.526
1.905GlnArg: 1.905 ± 0.729
1.27GlnSer: 1.27 ± 0.669
4.444GlnThr: 4.444 ± 1.792
3.81GlnVal: 3.81 ± 0.658
0.0GlnTrp: 0.0 ± 0.0
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
5.079ArgAla: 5.079 ± 2.675
0.635ArgCys: 0.635 ± 0.334
1.27ArgAsp: 1.27 ± 0.669
5.079ArgGlu: 5.079 ± 1.85
2.54ArgPhe: 2.54 ± 0.712
6.349ArgGly: 6.349 ± 2.4
0.635ArgHis: 0.635 ± 0.834
3.175ArgIle: 3.175 ± 1.672
4.444ArgLys: 4.444 ± 2.34
6.349ArgLeu: 6.349 ± 1.316
1.27ArgMet: 1.27 ± 0.52
2.54ArgAsn: 2.54 ± 0.403
4.444ArgPro: 4.444 ± 0.428
1.905ArgGln: 1.905 ± 0.626
4.444ArgArg: 4.444 ± 2.306
4.444ArgSer: 4.444 ± 1.207
5.714ArgThr: 5.714 ± 2.419
6.984ArgVal: 6.984 ± 2.565
2.54ArgTrp: 2.54 ± 0.403
0.635ArgTyr: 0.635 ± 0.334
0.0ArgXaa: 0.0 ± 0.0
Ser
4.444SerAla: 4.444 ± 0.428
1.905SerCys: 1.905 ± 1.003
2.54SerAsp: 2.54 ± 0.403
2.54SerGlu: 2.54 ± 0.403
1.27SerPhe: 1.27 ± 0.657
2.54SerGly: 2.54 ± 0.758
1.905SerHis: 1.905 ± 1.184
2.54SerIle: 2.54 ± 0.712
1.905SerLys: 1.905 ± 1.003
6.349SerLeu: 6.349 ± 1.626
0.635SerMet: 0.635 ± 0.698
0.635SerAsn: 0.635 ± 0.334
4.444SerPro: 4.444 ± 0.428
3.175SerGln: 3.175 ± 1.2
1.905SerArg: 1.905 ± 1.003
4.444SerSer: 4.444 ± 2.177
4.444SerThr: 4.444 ± 0.428
4.444SerVal: 4.444 ± 1.35
0.635SerTrp: 0.635 ± 0.698
0.635SerTyr: 0.635 ± 0.334
0.0SerXaa: 0.0 ± 0.0
Thr
3.175ThrAla: 3.175 ± 0.131
2.54ThrCys: 2.54 ± 1.478
1.905ThrAsp: 1.905 ± 1.464
1.905ThrGlu: 1.905 ± 1.003
3.81ThrPhe: 3.81 ± 1.559
6.984ThrGly: 6.984 ± 0.644
2.54ThrHis: 2.54 ± 1.314
2.54ThrIle: 2.54 ± 0.403
3.175ThrLys: 3.175 ± 2.567
3.81ThrLeu: 3.81 ± 1.27
2.54ThrMet: 2.54 ± 0.712
0.635ThrAsn: 0.635 ± 0.334
1.905ThrPro: 1.905 ± 0.729
2.54ThrGln: 2.54 ± 1.478
3.81ThrArg: 3.81 ± 1.559
4.444ThrSer: 4.444 ± 1.594
6.984ThrThr: 6.984 ± 1.91
3.175ThrVal: 3.175 ± 0.953
1.27ThrTrp: 1.27 ± 0.52
0.635ThrTyr: 0.635 ± 0.334
0.0ThrXaa: 0.0 ± 0.0
Val
5.079ValAla: 5.079 ± 1.594
0.635ValCys: 0.635 ± 0.334
2.54ValAsp: 2.54 ± 0.403
3.175ValGlu: 3.175 ± 0.131
4.444ValPhe: 4.444 ± 0.428
8.254ValGly: 8.254 ± 3.062
2.54ValHis: 2.54 ± 3.337
3.81ValIle: 3.81 ± 1.559
5.079ValLys: 5.079 ± 1.914
6.349ValLeu: 6.349 ± 1.626
3.175ValMet: 3.175 ± 0.98
1.27ValAsn: 1.27 ± 0.669
4.444ValPro: 4.444 ± 1.13
1.905ValGln: 1.905 ± 0.729
5.079ValArg: 5.079 ± 0.74
3.175ValSer: 3.175 ± 0.98
2.54ValThr: 2.54 ± 1.039
7.619ValVal: 7.619 ± 2.118
1.27ValTrp: 1.27 ± 1.668
0.0ValTyr: 0.0 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
0.635TrpAla: 0.635 ± 0.334
0.635TrpCys: 0.635 ± 0.334
1.27TrpAsp: 1.27 ± 0.52
2.54TrpGlu: 2.54 ± 0.758
1.905TrpPhe: 1.905 ± 0.526
0.635TrpGly: 0.635 ± 0.334
0.0TrpHis: 0.0 ± 0.0
1.905TrpIle: 1.905 ± 1.003
1.27TrpLys: 1.27 ± 0.669
1.905TrpLeu: 1.905 ± 0.626
1.27TrpMet: 1.27 ± 1.422
1.905TrpAsn: 1.905 ± 2.093
0.0TrpPro: 0.0 ± 0.0
0.635TrpGln: 0.635 ± 0.334
2.54TrpArg: 2.54 ± 1.039
1.27TrpSer: 1.27 ± 0.657
0.0TrpThr: 0.0 ± 0.0
1.905TrpVal: 1.905 ± 0.626
0.635TrpTrp: 0.635 ± 0.334
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.635TyrAla: 0.635 ± 0.334
0.0TyrCys: 0.0 ± 0.0
1.27TyrAsp: 1.27 ± 0.657
0.0TyrGlu: 0.0 ± 0.0
1.27TyrPhe: 1.27 ± 0.52
0.635TyrGly: 0.635 ± 0.334
1.27TyrHis: 1.27 ± 0.52
0.0TyrIle: 0.0 ± 0.0
1.27TyrLys: 1.27 ± 0.669
0.635TyrLeu: 0.635 ± 0.334
0.635TyrMet: 0.635 ± 0.334
0.635TyrAsn: 0.635 ± 0.334
1.27TyrPro: 1.27 ± 0.669
0.635TyrGln: 0.635 ± 0.698
0.635TyrArg: 0.635 ± 0.834
1.27TyrSer: 1.27 ± 0.669
0.635TyrThr: 0.635 ± 0.334
0.635TyrVal: 0.635 ± 0.334
0.0TyrTrp: 0.0 ± 0.0
0.635TyrTyr: 0.635 ± 0.334
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (1576 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski