Amino acid dipepetide frequency for Hubei toti-like virus 10

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
12.579AlaAla: 12.579 ± 0.327
0.524AlaCys: 0.524 ± 0.363
2.096AlaAsp: 2.096 ± 0.699
3.669AlaGlu: 3.669 ± 0.472
2.096AlaPhe: 2.096 ± 1.56
7.862AlaGly: 7.862 ± 2.84
1.048AlaHis: 1.048 ± 0.726
4.193AlaIle: 4.193 ± 0.644
3.145AlaLys: 3.145 ± 0.082
8.386AlaLeu: 8.386 ± 0.535
3.669AlaMet: 3.669 ± 0.281
3.145AlaAsn: 3.145 ± 0.835
6.289AlaPro: 6.289 ± 3.175
3.145AlaGln: 3.145 ± 0.835
4.193AlaArg: 4.193 ± 2.15
8.91AlaSer: 8.91 ± 2.114
4.717AlaThr: 4.717 ± 0.499
6.813AlaVal: 6.813 ± 2.059
0.524AlaTrp: 0.524 ± 0.363
1.572AlaTyr: 1.572 ± 0.417
0.0AlaXaa: 0.0 ± 0.0
Cys
0.524CysAla: 0.524 ± 0.363
0.524CysCys: 0.524 ± 0.363
1.572CysAsp: 1.572 ± 1.089
1.048CysGlu: 1.048 ± 0.726
1.048CysPhe: 1.048 ± 0.78
0.524CysGly: 0.524 ± 0.39
0.0CysHis: 0.0 ± 0.0
0.524CysIle: 0.524 ± 0.363
1.048CysLys: 1.048 ± 0.726
3.145CysLeu: 3.145 ± 1.424
1.048CysMet: 1.048 ± 0.027
0.0CysAsn: 0.0 ± 0.0
0.524CysPro: 0.524 ± 0.39
0.524CysGln: 0.524 ± 0.363
1.048CysArg: 1.048 ± 0.027
0.524CysSer: 0.524 ± 0.363
1.572CysThr: 1.572 ± 0.417
2.096CysVal: 2.096 ± 0.699
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
4.193AspAla: 4.193 ± 1.615
0.0AspCys: 0.0 ± 0.0
3.669AspAsp: 3.669 ± 0.281
1.572AspGlu: 1.572 ± 1.089
2.096AspPhe: 2.096 ± 0.699
3.669AspGly: 3.669 ± 1.034
0.524AspHis: 0.524 ± 0.363
3.669AspIle: 3.669 ± 0.281
2.621AspLys: 2.621 ± 1.814
5.765AspLeu: 5.765 ± 0.98
3.145AspMet: 3.145 ± 1.588
2.096AspAsn: 2.096 ± 0.054
1.048AspPro: 1.048 ± 0.78
0.0AspGln: 0.0 ± 0.0
2.096AspArg: 2.096 ± 1.451
4.193AspSer: 4.193 ± 0.644
1.048AspThr: 1.048 ± 0.726
4.193AspVal: 4.193 ± 0.862
3.145AspTrp: 3.145 ± 0.671
3.145AspTyr: 3.145 ± 0.671
0.0AspXaa: 0.0 ± 0.0
Glu
3.145GluAla: 3.145 ± 0.082
1.572GluCys: 1.572 ± 0.336
2.621GluAsp: 2.621 ± 0.308
5.241GluGlu: 5.241 ± 2.876
2.621GluPhe: 2.621 ± 0.445
1.572GluGly: 1.572 ± 0.417
0.524GluHis: 0.524 ± 0.39
2.096GluIle: 2.096 ± 0.054
2.096GluLys: 2.096 ± 0.054
5.241GluLeu: 5.241 ± 0.617
3.145GluMet: 3.145 ± 0.835
1.048GluAsn: 1.048 ± 0.726
1.572GluPro: 1.572 ± 0.336
0.524GluGln: 0.524 ± 0.39
4.193GluArg: 4.193 ± 0.644
5.241GluSer: 5.241 ± 2.876
0.524GluThr: 0.524 ± 0.363
3.145GluVal: 3.145 ± 0.082
2.096GluTrp: 2.096 ± 0.054
1.048GluTyr: 1.048 ± 0.027
0.0GluXaa: 0.0 ± 0.0
Phe
2.621PheAla: 2.621 ± 1.95
0.0PheCys: 0.0 ± 0.0
2.621PheAsp: 2.621 ± 0.445
3.669PheGlu: 3.669 ± 0.281
1.048PhePhe: 1.048 ± 0.78
1.048PheGly: 1.048 ± 0.027
0.524PheHis: 0.524 ± 0.39
2.096PheIle: 2.096 ± 0.807
1.048PheLys: 1.048 ± 0.726
2.096PheLeu: 2.096 ± 0.699
0.0PheMet: 0.0 ± 0.0
3.669PheAsn: 3.669 ± 0.281
1.572PhePro: 1.572 ± 0.336
1.572PheGln: 1.572 ± 0.417
0.524PheArg: 0.524 ± 0.39
3.145PheSer: 3.145 ± 0.835
1.572PheThr: 1.572 ± 0.417
1.048PheVal: 1.048 ± 0.78
0.0PheTrp: 0.0 ± 0.0
0.524PheTyr: 0.524 ± 0.39
0.0PheXaa: 0.0 ± 0.0
Gly
5.765GlyAla: 5.765 ± 1.279
1.048GlyCys: 1.048 ± 0.726
5.765GlyAsp: 5.765 ± 1.279
3.669GlyGlu: 3.669 ± 1.225
2.096GlyPhe: 2.096 ± 0.807
3.145GlyGly: 3.145 ± 0.835
1.572GlyHis: 1.572 ± 0.417
3.145GlyIle: 3.145 ± 0.671
3.145GlyLys: 3.145 ± 1.424
5.241GlyLeu: 5.241 ± 1.37
2.621GlyMet: 2.621 ± 1.198
3.145GlyAsn: 3.145 ± 1.588
5.765GlyPro: 5.765 ± 2.032
1.048GlyGln: 1.048 ± 0.78
5.241GlyArg: 5.241 ± 2.395
3.145GlySer: 3.145 ± 0.082
4.193GlyThr: 4.193 ± 0.644
5.241GlyVal: 5.241 ± 0.889
1.048GlyTrp: 1.048 ± 0.027
2.621GlyTyr: 2.621 ± 1.061
0.0GlyXaa: 0.0 ± 0.0
His
1.572HisAla: 1.572 ± 0.336
0.0HisCys: 0.0 ± 0.0
0.524HisAsp: 0.524 ± 0.363
1.572HisGlu: 1.572 ± 0.336
1.572HisPhe: 1.572 ± 0.417
0.524HisGly: 0.524 ± 0.363
1.572HisHis: 1.572 ± 0.417
1.572HisIle: 1.572 ± 0.417
0.0HisLys: 0.0 ± 0.0
2.096HisLeu: 2.096 ± 0.699
1.572HisMet: 1.572 ± 0.336
0.524HisAsn: 0.524 ± 0.39
1.572HisPro: 1.572 ± 0.336
1.048HisGln: 1.048 ± 0.027
1.572HisArg: 1.572 ± 0.417
0.524HisSer: 0.524 ± 0.363
1.048HisThr: 1.048 ± 0.726
1.572HisVal: 1.572 ± 1.17
1.048HisTrp: 1.048 ± 0.027
0.524HisTyr: 0.524 ± 0.39
0.0HisXaa: 0.0 ± 0.0
Ile
5.241IleAla: 5.241 ± 0.136
0.524IleCys: 0.524 ± 0.363
1.048IleAsp: 1.048 ± 0.027
2.096IleGlu: 2.096 ± 1.451
1.048IlePhe: 1.048 ± 0.027
3.145IleGly: 3.145 ± 0.835
2.096IleHis: 2.096 ± 0.807
1.048IleIle: 1.048 ± 0.78
2.096IleLys: 2.096 ± 0.054
3.145IleLeu: 3.145 ± 0.082
2.096IleMet: 2.096 ± 0.699
4.717IleAsn: 4.717 ± 1.252
1.048IlePro: 1.048 ± 0.726
2.096IleGln: 2.096 ± 0.699
2.096IleArg: 2.096 ± 0.054
4.193IleSer: 4.193 ± 0.109
3.145IleThr: 3.145 ± 1.588
3.669IleVal: 3.669 ± 0.281
1.572IleTrp: 1.572 ± 0.336
2.621IleTyr: 2.621 ± 0.445
0.0IleXaa: 0.0 ± 0.0
Lys
3.145LysAla: 3.145 ± 1.424
2.096LysCys: 2.096 ± 1.451
1.048LysAsp: 1.048 ± 0.726
0.524LysGlu: 0.524 ± 0.39
1.048LysPhe: 1.048 ± 0.726
1.048LysGly: 1.048 ± 0.726
2.096LysHis: 2.096 ± 0.699
1.048LysIle: 1.048 ± 0.027
2.096LysLys: 2.096 ± 1.451
2.621LysLeu: 2.621 ± 0.308
1.048LysMet: 1.048 ± 0.027
1.572LysAsn: 1.572 ± 0.336
1.572LysPro: 1.572 ± 1.089
2.096LysGln: 2.096 ± 0.054
2.621LysArg: 2.621 ± 1.814
1.048LysSer: 1.048 ± 0.726
1.048LysThr: 1.048 ± 0.027
4.193LysVal: 4.193 ± 0.109
0.524LysTrp: 0.524 ± 0.363
1.572LysTyr: 1.572 ± 0.336
0.0LysXaa: 0.0 ± 0.0
Leu
5.765LeuAla: 5.765 ± 2.032
2.621LeuCys: 2.621 ± 1.061
4.193LeuAsp: 4.193 ± 2.903
3.669LeuGlu: 3.669 ± 1.034
3.145LeuPhe: 3.145 ± 1.588
4.193LeuGly: 4.193 ± 0.862
2.096LeuHis: 2.096 ± 0.699
4.717LeuIle: 4.717 ± 1.007
2.096LeuLys: 2.096 ± 1.451
7.862LeuLeu: 7.862 ± 0.581
2.096LeuMet: 2.096 ± 0.054
3.145LeuAsn: 3.145 ± 1.424
2.096LeuPro: 2.096 ± 0.699
3.145LeuGln: 3.145 ± 1.588
9.434LeuArg: 9.434 ± 2.767
7.338LeuSer: 7.338 ± 2.068
5.241LeuThr: 5.241 ± 0.136
4.717LeuVal: 4.717 ± 0.254
2.096LeuTrp: 2.096 ± 0.699
2.096LeuTyr: 2.096 ± 0.054
0.0LeuXaa: 0.0 ± 0.0
Met
3.669MetAla: 3.669 ± 0.472
0.0MetCys: 0.0 ± 0.0
3.145MetAsp: 3.145 ± 0.082
2.096MetGlu: 2.096 ± 1.56
1.572MetPhe: 1.572 ± 0.336
2.621MetGly: 2.621 ± 0.308
0.0MetHis: 0.0 ± 0.0
1.048MetIle: 1.048 ± 0.726
0.524MetLys: 0.524 ± 0.363
2.621MetLeu: 2.621 ± 0.445
0.524MetMet: 0.524 ± 0.39
1.048MetAsn: 1.048 ± 0.027
1.572MetPro: 1.572 ± 1.17
2.621MetGln: 2.621 ± 0.308
1.572MetArg: 1.572 ± 0.336
4.717MetSer: 4.717 ± 0.499
1.572MetThr: 1.572 ± 0.336
4.717MetVal: 4.717 ± 2.005
0.524MetTrp: 0.524 ± 0.39
0.524MetTyr: 0.524 ± 0.363
0.0MetXaa: 0.0 ± 0.0
Asn
2.621AsnAla: 2.621 ± 1.198
1.048AsnCys: 1.048 ± 0.027
2.621AsnAsp: 2.621 ± 0.308
1.572AsnGlu: 1.572 ± 0.417
0.524AsnPhe: 0.524 ± 0.363
2.621AsnGly: 2.621 ± 1.198
0.524AsnHis: 0.524 ± 0.39
1.572AsnIle: 1.572 ± 1.17
2.621AsnLys: 2.621 ± 1.061
3.145AsnLeu: 3.145 ± 1.424
1.048AsnMet: 1.048 ± 0.991
1.048AsnAsn: 1.048 ± 0.78
2.621AsnPro: 2.621 ± 1.198
2.621AsnGln: 2.621 ± 0.308
2.096AsnArg: 2.096 ± 0.807
2.096AsnSer: 2.096 ± 0.054
1.572AsnThr: 1.572 ± 0.417
5.765AsnVal: 5.765 ± 0.98
1.048AsnTrp: 1.048 ± 0.027
1.572AsnTyr: 1.572 ± 1.089
0.0AsnXaa: 0.0 ± 0.0
Pro
5.765ProAla: 5.765 ± 2.785
0.524ProCys: 0.524 ± 0.39
1.572ProAsp: 1.572 ± 0.336
2.096ProGlu: 2.096 ± 0.807
0.524ProPhe: 0.524 ± 0.39
4.193ProGly: 4.193 ± 0.862
0.524ProHis: 0.524 ± 0.363
3.145ProIle: 3.145 ± 0.835
1.572ProLys: 1.572 ± 1.17
2.096ProLeu: 2.096 ± 1.56
1.572ProMet: 1.572 ± 0.417
2.096ProAsn: 2.096 ± 0.807
3.669ProPro: 3.669 ± 1.225
0.524ProGln: 0.524 ± 0.39
3.145ProArg: 3.145 ± 0.082
4.717ProSer: 4.717 ± 1.007
3.145ProThr: 3.145 ± 0.082
7.862ProVal: 7.862 ± 1.334
0.0ProTrp: 0.0 ± 0.0
2.096ProTyr: 2.096 ± 0.699
0.0ProXaa: 0.0 ± 0.0
Gln
4.717GlnAla: 4.717 ± 2.005
0.524GlnCys: 0.524 ± 0.363
2.096GlnAsp: 2.096 ± 0.807
2.096GlnGlu: 2.096 ± 0.807
1.048GlnPhe: 1.048 ± 0.027
2.096GlnGly: 2.096 ± 0.699
1.048GlnHis: 1.048 ± 0.027
1.048GlnIle: 1.048 ± 0.726
0.524GlnLys: 0.524 ± 0.39
3.669GlnLeu: 3.669 ± 0.472
0.524GlnMet: 0.524 ± 0.363
0.524GlnAsn: 0.524 ± 0.39
2.096GlnPro: 2.096 ± 0.807
1.048GlnGln: 1.048 ± 0.78
1.572GlnArg: 1.572 ± 0.336
3.145GlnSer: 3.145 ± 0.671
2.096GlnThr: 2.096 ± 0.807
3.145GlnVal: 3.145 ± 0.835
1.048GlnTrp: 1.048 ± 0.726
0.524GlnTyr: 0.524 ± 0.39
0.0GlnXaa: 0.0 ± 0.0
Arg
3.145ArgAla: 3.145 ± 1.424
1.572ArgCys: 1.572 ± 1.17
1.572ArgAsp: 1.572 ± 0.336
3.145ArgGlu: 3.145 ± 1.588
1.572ArgPhe: 1.572 ± 0.417
7.862ArgGly: 7.862 ± 1.334
1.048ArgHis: 1.048 ± 0.78
2.096ArgIle: 2.096 ± 0.054
1.572ArgLys: 1.572 ± 0.336
4.193ArgLeu: 4.193 ± 2.15
1.048ArgMet: 1.048 ± 0.726
1.572ArgAsn: 1.572 ± 1.17
2.621ArgPro: 2.621 ± 0.445
2.096ArgGln: 2.096 ± 0.699
6.289ArgArg: 6.289 ± 3.601
4.717ArgSer: 4.717 ± 1.76
4.717ArgThr: 4.717 ± 0.254
6.813ArgVal: 6.813 ± 2.458
1.048ArgTrp: 1.048 ± 0.027
2.621ArgTyr: 2.621 ± 1.061
0.0ArgXaa: 0.0 ± 0.0
Ser
7.338SerAla: 7.338 ± 0.191
1.572SerCys: 1.572 ± 1.17
4.717SerAsp: 4.717 ± 0.254
3.669SerGlu: 3.669 ± 1.787
1.572SerPhe: 1.572 ± 0.336
8.386SerGly: 8.386 ± 1.724
1.572SerHis: 1.572 ± 1.089
3.669SerIle: 3.669 ± 0.281
3.669SerLys: 3.669 ± 2.54
5.765SerLeu: 5.765 ± 1.733
3.669SerMet: 3.669 ± 0.472
2.096SerAsn: 2.096 ± 0.054
3.145SerPro: 3.145 ± 2.177
2.096SerGln: 2.096 ± 0.054
4.717SerArg: 4.717 ± 0.254
9.958SerSer: 9.958 ± 0.871
8.91SerThr: 8.91 ± 1.361
5.241SerVal: 5.241 ± 0.889
2.621SerTrp: 2.621 ± 0.308
1.572SerTyr: 1.572 ± 0.336
0.0SerXaa: 0.0 ± 0.0
Thr
3.669ThrAla: 3.669 ± 0.281
1.048ThrCys: 1.048 ± 0.726
2.621ThrAsp: 2.621 ± 1.061
2.096ThrGlu: 2.096 ± 1.451
1.048ThrPhe: 1.048 ± 0.78
5.241ThrGly: 5.241 ± 0.136
1.572ThrHis: 1.572 ± 0.417
4.193ThrIle: 4.193 ± 0.109
1.048ThrLys: 1.048 ± 0.027
7.338ThrLeu: 7.338 ± 0.562
2.096ThrMet: 2.096 ± 0.054
3.669ThrAsn: 3.669 ± 1.034
2.096ThrPro: 2.096 ± 1.56
3.145ThrGln: 3.145 ± 0.835
2.096ThrArg: 2.096 ± 0.807
4.193ThrSer: 4.193 ± 0.862
4.717ThrThr: 4.717 ± 1.252
3.669ThrVal: 3.669 ± 0.472
0.0ThrTrp: 0.0 ± 0.0
1.048ThrTyr: 1.048 ± 0.027
0.0ThrXaa: 0.0 ± 0.0
Val
8.91ValAla: 8.91 ± 0.145
0.524ValCys: 0.524 ± 0.363
5.241ValAsp: 5.241 ± 0.889
3.669ValGlu: 3.669 ± 1.034
2.621ValPhe: 2.621 ± 0.308
5.765ValGly: 5.765 ± 0.526
1.572ValHis: 1.572 ± 0.336
4.717ValIle: 4.717 ± 2.005
2.096ValLys: 2.096 ± 0.699
4.717ValLeu: 4.717 ± 0.499
2.621ValMet: 2.621 ± 0.445
4.193ValAsn: 4.193 ± 0.644
6.289ValPro: 6.289 ± 3.175
2.621ValGln: 2.621 ± 1.198
4.717ValArg: 4.717 ± 0.499
9.958ValSer: 9.958 ± 0.635
4.193ValThr: 4.193 ± 1.397
8.91ValVal: 8.91 ± 0.608
2.096ValTrp: 2.096 ± 0.054
3.669ValTyr: 3.669 ± 1.225
0.0ValXaa: 0.0 ± 0.0
Trp
3.145TrpAla: 3.145 ± 0.082
0.524TrpCys: 0.524 ± 0.363
0.524TrpAsp: 0.524 ± 0.39
1.048TrpGlu: 1.048 ± 0.726
0.524TrpPhe: 0.524 ± 0.363
1.572TrpGly: 1.572 ± 0.336
1.048TrpHis: 1.048 ± 0.027
1.572TrpIle: 1.572 ± 0.336
0.524TrpLys: 0.524 ± 0.363
1.048TrpLeu: 1.048 ± 0.027
1.572TrpMet: 1.572 ± 0.336
0.0TrpAsn: 0.0 ± 0.0
0.524TrpPro: 0.524 ± 0.363
1.048TrpGln: 1.048 ± 0.027
1.048TrpArg: 1.048 ± 0.78
1.572TrpSer: 1.572 ± 0.336
0.524TrpThr: 0.524 ± 0.39
2.621TrpVal: 2.621 ± 0.308
0.0TrpTrp: 0.0 ± 0.0
0.524TrpTyr: 0.524 ± 0.363
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.048TyrAla: 1.048 ± 0.726
1.048TyrCys: 1.048 ± 0.726
2.621TyrAsp: 2.621 ± 1.061
1.048TyrGlu: 1.048 ± 0.726
1.572TyrPhe: 1.572 ± 0.417
1.572TyrGly: 1.572 ± 0.417
1.048TyrHis: 1.048 ± 0.027
1.572TyrIle: 1.572 ± 0.417
0.524TyrLys: 0.524 ± 0.363
1.572TyrLeu: 1.572 ± 0.336
1.048TyrMet: 1.048 ± 0.277
1.572TyrAsn: 1.572 ± 0.417
3.145TyrPro: 3.145 ± 0.835
1.572TyrGln: 1.572 ± 0.336
1.048TyrArg: 1.048 ± 0.726
2.621TyrSer: 2.621 ± 0.445
1.048TyrThr: 1.048 ± 0.726
3.669TyrVal: 3.669 ± 0.281
0.524TyrTrp: 0.524 ± 0.39
1.048TyrTyr: 1.048 ± 0.726
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1909 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski