Amino acid dipepetide frequency for Elizabethkingia sp. JS20170427COW

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	4.062AlaAla: 4.062 ± 0.094	0.562AlaCys: 0.562 ± 0.029	3.151AlaAsp: 3.151 ± 0.066	4.471AlaGlu: 4.471 ± 0.097	3.268AlaPhe: 3.268 ± 0.069	4.01AlaGly: 4.01 ± 0.067	1.241AlaHis: 1.241 ± 0.043	5.039AlaIle: 5.039 ± 0.088	5.157AlaLys: 5.157 ± 0.093	6.498AlaLeu: 6.498 ± 0.117	1.565AlaMet: 1.565 ± 0.046	3.245AlaAsn: 3.245 ± 0.067	1.914AlaPro: 1.914 ± 0.055	2.931AlaGln: 2.931 ± 0.065	2.025AlaArg: 2.025 ± 0.06	4.117AlaSer: 4.117 ± 0.087	3.431AlaThr: 3.431 ± 0.073	3.849AlaVal: 3.849 ± 0.084	0.678AlaTrp: 0.678 ± 0.031	2.632AlaTyr: 2.632 ± 0.051	0.0AlaXaa: 0.0 ± 0.0
Cys	0.427CysAla: 0.427 ± 0.024	0.096CysCys: 0.096 ± 0.011	0.33CysAsp: 0.33 ± 0.02	0.401CysGlu: 0.401 ± 0.024	0.422CysPhe: 0.422 ± 0.024	0.619CysGly: 0.619 ± 0.027	0.177CysHis: 0.177 ± 0.017	0.613CysIle: 0.613 ± 0.03	0.494CysLys: 0.494 ± 0.025	0.668CysLeu: 0.668 ± 0.032	0.168CysMet: 0.168 ± 0.014	0.372CysAsn: 0.372 ± 0.022	0.325CysPro: 0.325 ± 0.024	0.24CysGln: 0.24 ± 0.018	0.215CysArg: 0.215 ± 0.015	0.483CysSer: 0.483 ± 0.022	0.399CysThr: 0.399 ± 0.027	0.391CysVal: 0.391 ± 0.021	0.056CysTrp: 0.056 ± 0.009	0.312CysTyr: 0.312 ± 0.02	0.0CysXaa: 0.0 ± 0.0
Asp	3.359AspAla: 3.359 ± 0.074	0.358AspCys: 0.358 ± 0.022	2.278AspAsp: 2.278 ± 0.057	3.594AspGlu: 3.594 ± 0.081	3.805AspPhe: 3.805 ± 0.077	3.183AspGly: 3.183 ± 0.064	0.914AspHis: 0.914 ± 0.037	4.333AspIle: 4.333 ± 0.071	4.17AspLys: 4.17 ± 0.085	5.051AspLeu: 5.051 ± 0.078	1.008AspMet: 1.008 ± 0.036	2.634AspAsn: 2.634 ± 0.063	1.656AspPro: 1.656 ± 0.049	1.692AspGln: 1.692 ± 0.053	1.881AspArg: 1.881 ± 0.058	2.743AspSer: 2.743 ± 0.066	2.378AspThr: 2.378 ± 0.053	2.971AspVal: 2.971 ± 0.06	0.716AspTrp: 0.716 ± 0.032	2.706AspTyr: 2.706 ± 0.069	0.0AspXaa: 0.0 ± 0.0
Glu	4.545GluAla: 4.545 ± 0.085	0.326GluCys: 0.326 ± 0.02	3.509GluAsp: 3.509 ± 0.071	5.703GluGlu: 5.703 ± 0.122	2.866GluPhe: 2.866 ± 0.064	3.761GluGly: 3.761 ± 0.073	1.116GluHis: 1.116 ± 0.039	6.145GluIle: 6.145 ± 0.096	6.895GluLys: 6.895 ± 0.099	6.003GluLeu: 6.003 ± 0.107	1.682GluMet: 1.682 ± 0.044	4.781GluAsn: 4.781 ± 0.084	1.346GluPro: 1.346 ± 0.041	2.487GluGln: 2.487 ± 0.058	2.371GluArg: 2.371 ± 0.064	3.027GluSer: 3.027 ± 0.062	3.222GluThr: 3.222 ± 0.063	4.699GluVal: 4.699 ± 0.094	0.703GluTrp: 0.703 ± 0.033	2.714GluTyr: 2.714 ± 0.063	0.0GluXaa: 0.0 ± 0.0
Phe	3.224PheAla: 3.224 ± 0.068	0.459PheCys: 0.459 ± 0.025	2.827PheAsp: 2.827 ± 0.065	2.985PheGlu: 2.985 ± 0.065	2.825PhePhe: 2.825 ± 0.078	3.681PheGly: 3.681 ± 0.083	0.965PheHis: 0.965 ± 0.032	4.071PheIle: 4.071 ± 0.092	3.537PheLys: 3.537 ± 0.066	4.943PheLeu: 4.943 ± 0.109	1.194PheMet: 1.194 ± 0.043	3.067PheAsn: 3.067 ± 0.07	1.911PhePro: 1.911 ± 0.052	1.9PheGln: 1.9 ± 0.052	1.72PheArg: 1.72 ± 0.05	4.128PheSer: 4.128 ± 0.086	2.904PheThr: 2.904 ± 0.063	2.954PheVal: 2.954 ± 0.069	0.612PheTrp: 0.612 ± 0.033	2.29PheTyr: 2.29 ± 0.055	0.0PheXaa: 0.0 ± 0.0
Gly	4.141GlyAla: 4.141 ± 0.085	0.501GlyCys: 0.501 ± 0.028	3.182GlyAsp: 3.182 ± 0.064	3.774GlyGlu: 3.774 ± 0.076	3.598GlyPhe: 3.598 ± 0.074	4.536GlyGly: 4.536 ± 0.104	1.06GlyHis: 1.06 ± 0.036	5.545GlyIle: 5.545 ± 0.094	5.706GlyLys: 5.706 ± 0.091	5.651GlyLeu: 5.651 ± 0.08	1.676GlyMet: 1.676 ± 0.051	3.745GlyAsn: 3.745 ± 0.087	1.185GlyPro: 1.185 ± 0.04	1.943GlyGln: 1.943 ± 0.05	2.148GlyArg: 2.148 ± 0.051	3.928GlySer: 3.928 ± 0.075	3.332GlyThr: 3.332 ± 0.08	4.339GlyVal: 4.339 ± 0.083	0.762GlyTrp: 0.762 ± 0.035	2.923GlyTyr: 2.923 ± 0.075	0.0GlyXaa: 0.0 ± 0.0
His	1.0HisAla: 1.0 ± 0.034	0.185HisCys: 0.185 ± 0.015	0.813HisAsp: 0.813 ± 0.034	1.054HisGlu: 1.054 ± 0.034	1.213HisPhe: 1.213 ± 0.042	1.047HisGly: 1.047 ± 0.039	0.659HisHis: 0.659 ± 0.032	1.32HisIle: 1.32 ± 0.046	1.238HisLys: 1.238 ± 0.04	2.032HisLeu: 2.032 ± 0.05	0.326HisMet: 0.326 ± 0.019	0.989HisAsn: 0.989 ± 0.04	1.017HisPro: 1.017 ± 0.036	1.121HisGln: 1.121 ± 0.04	0.664HisArg: 0.664 ± 0.032	1.203HisSer: 1.203 ± 0.041	0.931HisThr: 0.931 ± 0.038	0.836HisVal: 0.836 ± 0.039	0.241HisTrp: 0.241 ± 0.021	0.963HisTyr: 0.963 ± 0.038	0.0HisXaa: 0.0 ± 0.0
Ile	5.475IleAla: 5.475 ± 0.093	0.674IleCys: 0.674 ± 0.025	4.419IleAsp: 4.419 ± 0.074	5.236IleGlu: 5.236 ± 0.094	3.979IlePhe: 3.979 ± 0.089	5.015IleGly: 5.015 ± 0.097	1.528IleHis: 1.528 ± 0.049	6.191IleIle: 6.191 ± 0.105	5.958IleLys: 5.958 ± 0.099	7.552IleLeu: 7.552 ± 0.137	1.468IleMet: 1.468 ± 0.044	4.462IleAsn: 4.462 ± 0.082	3.466IlePro: 3.466 ± 0.08	3.17IleGln: 3.17 ± 0.056	2.474IleArg: 2.474 ± 0.055	6.134IleSer: 6.134 ± 0.101	4.314IleThr: 4.314 ± 0.086	4.36IleVal: 4.36 ± 0.084	0.654IleTrp: 0.654 ± 0.028	2.951IleTyr: 2.951 ± 0.062	0.0IleXaa: 0.0 ± 0.0
Lys	5.27LysAla: 5.27 ± 0.087	0.373LysCys: 0.373 ± 0.026	4.8LysAsp: 4.8 ± 0.086	6.484LysGlu: 6.484 ± 0.105	3.257LysPhe: 3.257 ± 0.064	4.79LysGly: 4.79 ± 0.084	1.288LysHis: 1.288 ± 0.045	7.23LysIle: 7.23 ± 0.096	7.367LysLys: 7.367 ± 0.132	6.693LysLeu: 6.693 ± 0.1	2.226LysMet: 2.226 ± 0.051	6.003LysAsn: 6.003 ± 0.104	2.468LysPro: 2.468 ± 0.055	2.708LysGln: 2.708 ± 0.062	2.68LysArg: 2.68 ± 0.069	4.653LysSer: 4.653 ± 0.079	4.63LysThr: 4.63 ± 0.091	5.309LysVal: 5.309 ± 0.08	0.743LysTrp: 0.743 ± 0.032	3.273LysTyr: 3.273 ± 0.065	0.0LysXaa: 0.0 ± 0.0
Leu	6.186LeuAla: 6.186 ± 0.103	0.701LeuCys: 0.701 ± 0.034	4.851LeuAsp: 4.851 ± 0.075	6.305LeuGlu: 6.305 ± 0.11	4.714LeuPhe: 4.714 ± 0.108	6.457LeuGly: 6.457 ± 0.095	1.739LeuHis: 1.739 ± 0.051	6.449LeuIle: 6.449 ± 0.119	8.153LeuLys: 8.153 ± 0.097	8.727LeuLeu: 8.727 ± 0.17	2.257LeuMet: 2.257 ± 0.059	5.304LeuAsn: 5.304 ± 0.084	3.751LeuPro: 3.751 ± 0.068	4.014LeuGln: 4.014 ± 0.071	3.063LeuArg: 3.063 ± 0.064	7.028LeuSer: 7.028 ± 0.102	4.514LeuThr: 4.514 ± 0.078	5.283LeuVal: 5.283 ± 0.1	0.901LeuTrp: 0.901 ± 0.034	3.507LeuTyr: 3.507 ± 0.074	0.0LeuXaa: 0.0 ± 0.0
Met	1.595MetAla: 1.595 ± 0.047	0.116MetCys: 0.116 ± 0.013	1.125MetAsp: 1.125 ± 0.04	1.478MetGlu: 1.478 ± 0.038	0.822MetPhe: 0.822 ± 0.035	1.569MetGly: 1.569 ± 0.044	0.385MetHis: 0.385 ± 0.023	1.621MetIle: 1.621 ± 0.044	2.486MetLys: 2.486 ± 0.058	2.062MetLeu: 2.062 ± 0.062	0.756MetMet: 0.756 ± 0.036	1.348MetAsn: 1.348 ± 0.038	0.838MetPro: 0.838 ± 0.031	0.858MetGln: 0.858 ± 0.035	0.828MetArg: 0.828 ± 0.034	1.404MetSer: 1.404 ± 0.047	1.084MetThr: 1.084 ± 0.038	1.465MetVal: 1.465 ± 0.045	0.183MetTrp: 0.183 ± 0.017	0.71MetTyr: 0.71 ± 0.033	0.0MetXaa: 0.0 ± 0.0
Asn	3.551AsnAla: 3.551 ± 0.073	0.373AsnCys: 0.373 ± 0.022	2.629AsnAsp: 2.629 ± 0.069	3.131AsnGlu: 3.131 ± 0.064	3.389AsnPhe: 3.389 ± 0.071	3.555AsnGly: 3.555 ± 0.09	1.302AsnHis: 1.302 ± 0.043	5.271AsnIle: 5.271 ± 0.089	4.309AsnLys: 4.309 ± 0.084	5.721AsnLeu: 5.721 ± 0.09	1.142AsnMet: 1.142 ± 0.037	3.513AsnAsn: 3.513 ± 0.099	2.941AsnPro: 2.941 ± 0.053	2.588AsnGln: 2.588 ± 0.066	2.053AsnArg: 2.053 ± 0.05	3.522AsnSer: 3.522 ± 0.077	3.48AsnThr: 3.48 ± 0.091	2.931AsnVal: 2.931 ± 0.067	0.766AsnTrp: 0.766 ± 0.035	2.869AsnTyr: 2.869 ± 0.076	0.0AsnXaa: 0.0 ± 0.0
Pro	1.899ProAla: 1.899 ± 0.056	0.236ProCys: 0.236 ± 0.02	1.771ProAsp: 1.771 ± 0.044	3.196ProGlu: 3.196 ± 0.071	1.87ProPhe: 1.87 ± 0.055	1.984ProGly: 1.984 ± 0.052	0.678ProHis: 0.678 ± 0.033	2.692ProIle: 2.692 ± 0.055	2.866ProLys: 2.866 ± 0.069	2.957ProLeu: 2.957 ± 0.056	0.808ProMet: 0.808 ± 0.036	2.235ProAsn: 2.235 ± 0.057	0.738ProPro: 0.738 ± 0.035	1.44ProGln: 1.44 ± 0.042	1.018ProArg: 1.018 ± 0.037	2.378ProSer: 2.378 ± 0.056	1.975ProThr: 1.975 ± 0.053	2.153ProVal: 2.153 ± 0.061	0.353ProTrp: 0.353 ± 0.019	1.56ProTyr: 1.56 ± 0.044	0.0ProXaa: 0.0 ± 0.0
Gln	2.478GlnAla: 2.478 ± 0.063	0.178GlnCys: 0.178 ± 0.016	1.98GlnAsp: 1.98 ± 0.056	3.047GlnGlu: 3.047 ± 0.072	1.696GlnPhe: 1.696 ± 0.049	2.13GlnGly: 2.13 ± 0.059	0.807GlnHis: 0.807 ± 0.033	2.81GlnIle: 2.81 ± 0.058	3.947GlnLys: 3.947 ± 0.071	4.098GlnLeu: 4.098 ± 0.074	0.916GlnMet: 0.916 ± 0.038	2.688GlnAsn: 2.688 ± 0.062	1.325GlnPro: 1.325 ± 0.041	2.148GlnGln: 2.148 ± 0.062	1.385GlnArg: 1.385 ± 0.045	2.302GlnSer: 2.302 ± 0.057	1.795GlnThr: 1.795 ± 0.054	2.217GlnVal: 2.217 ± 0.061	0.482GlnTrp: 0.482 ± 0.023	1.828GlnTyr: 1.828 ± 0.045	0.0GlnXaa: 0.0 ± 0.0
Arg	2.004ArgAla: 2.004 ± 0.061	0.206ArgCys: 0.206 ± 0.016	1.702ArgAsp: 1.702 ± 0.051	2.324ArgGlu: 2.324 ± 0.072	1.817ArgPhe: 1.817 ± 0.052	1.902ArgGly: 1.902 ± 0.051	0.604ArgHis: 0.604 ± 0.026	2.787ArgIle: 2.787 ± 0.062	2.92ArgLys: 2.92 ± 0.067	3.058ArgLeu: 3.058 ± 0.061	0.872ArgMet: 0.872 ± 0.039	2.299ArgAsn: 2.299 ± 0.059	1.135ArgPro: 1.135 ± 0.042	1.196ArgGln: 1.196 ± 0.037	1.337ArgArg: 1.337 ± 0.045	1.77ArgSer: 1.77 ± 0.046	1.612ArgThr: 1.612 ± 0.044	1.992ArgVal: 1.992 ± 0.051	0.409ArgTrp: 0.409 ± 0.022	1.492ArgTyr: 1.492 ± 0.044	0.0ArgXaa: 0.0 ± 0.0
Ser	3.898SerAla: 3.898 ± 0.075	0.607SerCys: 0.607 ± 0.026	3.164SerAsp: 3.164 ± 0.058	4.037SerGlu: 4.037 ± 0.087	3.916SerPhe: 3.916 ± 0.08	4.511SerGly: 4.511 ± 0.08	1.168SerHis: 1.168 ± 0.034	5.102SerIle: 5.102 ± 0.091	4.718SerLys: 4.718 ± 0.07	6.293SerLeu: 6.293 ± 0.105	1.334SerMet: 1.334 ± 0.039	3.36SerAsn: 3.36 ± 0.082	2.294SerPro: 2.294 ± 0.052	2.663SerGln: 2.663 ± 0.053	2.053SerArg: 2.053 ± 0.054	4.327SerSer: 4.327 ± 0.1	3.396SerThr: 3.396 ± 0.075	3.851SerVal: 3.851 ± 0.078	0.768SerTrp: 0.768 ± 0.03	2.844SerTyr: 2.844 ± 0.066	0.0SerXaa: 0.0 ± 0.0
Thr	3.44ThrAla: 3.44 ± 0.06	0.327ThrCys: 0.327 ± 0.025	2.696ThrAsp: 2.696 ± 0.063	3.41ThrGlu: 3.41 ± 0.069	2.592ThrPhe: 2.592 ± 0.059	3.531ThrGly: 3.531 ± 0.076	1.115ThrHis: 1.115 ± 0.037	4.061ThrIle: 4.061 ± 0.078	3.657ThrLys: 3.657 ± 0.067	5.158ThrLeu: 5.158 ± 0.086	0.928ThrMet: 0.928 ± 0.036	2.522ThrAsn: 2.522 ± 0.065	2.486ThrPro: 2.486 ± 0.07	2.374ThrGln: 2.374 ± 0.054	1.572ThrArg: 1.572 ± 0.047	3.6ThrSer: 3.6 ± 0.079	3.01ThrThr: 3.01 ± 0.081	3.031ThrVal: 3.031 ± 0.07	0.548ThrTrp: 0.548 ± 0.029	2.051ThrTyr: 2.051 ± 0.053	0.0ThrXaa: 0.0 ± 0.0
Val	4.174ValAla: 4.174 ± 0.093	0.478ValCys: 0.478 ± 0.025	3.261ValAsp: 3.261 ± 0.065	4.131ValGlu: 4.131 ± 0.074	3.047ValPhe: 3.047 ± 0.075	3.973ValGly: 3.973 ± 0.075	0.949ValHis: 0.949 ± 0.034	4.447ValIle: 4.447 ± 0.077	4.704ValLys: 4.704 ± 0.088	5.553ValLeu: 5.553 ± 0.101	1.301ValMet: 1.301 ± 0.042	3.324ValAsn: 3.324 ± 0.074	2.077ValPro: 2.077 ± 0.051	1.986ValGln: 1.986 ± 0.047	1.93ValArg: 1.93 ± 0.053	4.117ValSer: 4.117 ± 0.085	2.868ValThr: 2.868 ± 0.069	4.021ValVal: 4.021 ± 0.084	0.559ValTrp: 0.559 ± 0.025	2.388ValTyr: 2.388 ± 0.063	0.0ValXaa: 0.0 ± 0.0
Trp	0.647TrpAla: 0.647 ± 0.024	0.092TrpCys: 0.092 ± 0.012	0.594TrpAsp: 0.594 ± 0.033	0.821TrpGlu: 0.821 ± 0.04	0.493TrpPhe: 0.493 ± 0.028	0.742TrpGly: 0.742 ± 0.037	0.181TrpHis: 0.181 ± 0.015	0.785TrpIle: 0.785 ± 0.035	0.965TrpLys: 0.965 ± 0.037	1.003TrpLeu: 1.003 ± 0.032	0.335TrpMet: 0.335 ± 0.021	0.698TrpAsn: 0.698 ± 0.03	0.224TrpPro: 0.224 ± 0.018	0.426TrpGln: 0.426 ± 0.025	0.372TrpArg: 0.372 ± 0.023	0.57TrpSer: 0.57 ± 0.03	0.547TrpThr: 0.547 ± 0.026	0.714TrpVal: 0.714 ± 0.031	0.136TrpTrp: 0.136 ± 0.014	0.441TrpTyr: 0.441 ± 0.027	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.471TyrAla: 2.471 ± 0.062	0.361TyrCys: 0.361 ± 0.023	2.35TyrAsp: 2.35 ± 0.059	2.322TyrGlu: 2.322 ± 0.057	2.607TyrPhe: 2.607 ± 0.061	2.678TyrGly: 2.678 ± 0.071	0.977TyrHis: 0.977 ± 0.039	2.969TyrIle: 2.969 ± 0.064	2.997TyrLys: 2.997 ± 0.065	4.186TyrLeu: 4.186 ± 0.078	0.772TyrMet: 0.772 ± 0.032	2.446TyrAsn: 2.446 ± 0.068	1.709TyrPro: 1.709 ± 0.048	2.375TyrGln: 2.375 ± 0.06	1.649TyrArg: 1.649 ± 0.045	2.867TyrSer: 2.867 ± 0.071	2.285TyrThr: 2.285 ± 0.065	1.923TyrVal: 1.923 ± 0.05	0.513TyrTrp: 0.513 ± 0.027	2.059TyrTyr: 2.059 ± 0.068	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2276 proteins (784826 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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