Amino acid dipepetide frequency for Pseudomonas phage pf8_ST274-AUS411

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
11.659AlaAla: 11.659 ± 3.321
1.332AlaCys: 1.332 ± 0.549
3.997AlaAsp: 3.997 ± 0.83
3.664AlaGlu: 3.664 ± 0.657
2.665AlaPhe: 2.665 ± 1.27
5.996AlaGly: 5.996 ± 2.284
1.999AlaHis: 1.999 ± 0.921
4.997AlaIle: 4.997 ± 0.618
4.997AlaLys: 4.997 ± 0.966
11.326AlaLeu: 11.326 ± 2.372
1.666AlaMet: 1.666 ± 0.917
2.332AlaAsn: 2.332 ± 0.872
6.329AlaPro: 6.329 ± 2.044
4.997AlaGln: 4.997 ± 1.645
5.996AlaArg: 5.996 ± 1.73
6.329AlaSer: 6.329 ± 1.164
4.664AlaThr: 4.664 ± 0.864
7.328AlaVal: 7.328 ± 1.428
2.665AlaTrp: 2.665 ± 1.094
1.999AlaTyr: 1.999 ± 1.038
0.0AlaXaa: 0.0 ± 0.0
Cys
1.332CysAla: 1.332 ± 0.631
0.0CysCys: 0.0 ± 0.0
0.999CysAsp: 0.999 ± 0.603
1.666CysGlu: 1.666 ± 0.823
0.0CysPhe: 0.0 ± 0.0
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.666CysIle: 0.666 ± 0.504
1.332CysLys: 1.332 ± 0.715
1.332CysLeu: 1.332 ± 0.69
0.333CysMet: 0.333 ± 0.417
1.332CysAsn: 1.332 ± 0.741
0.666CysPro: 0.666 ± 0.378
0.333CysGln: 0.333 ± 0.307
1.999CysArg: 1.999 ± 0.958
0.666CysSer: 0.666 ± 0.614
0.666CysThr: 0.666 ± 0.539
1.666CysVal: 1.666 ± 0.78
0.0CysTrp: 0.0 ± 0.0
0.333CysTyr: 0.333 ± 0.307
0.0CysXaa: 0.0 ± 0.0
Asp
4.33AspAla: 4.33 ± 0.901
0.333AspCys: 0.333 ± 0.307
3.331AspAsp: 3.331 ± 1.074
1.999AspGlu: 1.999 ± 0.656
3.997AspPhe: 3.997 ± 1.745
9.327AspGly: 9.327 ± 3.008
1.332AspHis: 1.332 ± 0.668
1.999AspIle: 1.999 ± 1.126
2.665AspLys: 2.665 ± 0.847
5.663AspLeu: 5.663 ± 1.359
1.332AspMet: 1.332 ± 0.708
1.332AspAsn: 1.332 ± 0.895
4.664AspPro: 4.664 ± 1.477
0.999AspGln: 0.999 ± 0.689
3.997AspArg: 3.997 ± 1.178
2.665AspSer: 2.665 ± 0.883
2.332AspThr: 2.332 ± 0.421
1.666AspVal: 1.666 ± 0.812
0.333AspTrp: 0.333 ± 0.41
2.332AspTyr: 2.332 ± 0.525
0.0AspXaa: 0.0 ± 0.0
Glu
4.997GluAla: 4.997 ± 1.288
0.666GluCys: 0.666 ± 0.378
3.331GluAsp: 3.331 ± 0.862
1.999GluGlu: 1.999 ± 1.098
2.332GluPhe: 2.332 ± 1.053
4.997GluGly: 4.997 ± 0.994
0.999GluHis: 0.999 ± 0.578
3.331GluIle: 3.331 ± 1.214
1.999GluLys: 1.999 ± 0.878
4.997GluLeu: 4.997 ± 1.256
1.332GluMet: 1.332 ± 0.539
0.666GluAsn: 0.666 ± 0.377
2.998GluPro: 2.998 ± 1.206
1.666GluGln: 1.666 ± 0.626
2.998GluArg: 2.998 ± 1.13
2.665GluSer: 2.665 ± 0.848
4.33GluThr: 4.33 ± 1.1
1.999GluVal: 1.999 ± 0.748
0.999GluTrp: 0.999 ± 0.507
1.999GluTyr: 1.999 ± 0.584
0.0GluXaa: 0.0 ± 0.0
Phe
4.33PheAla: 4.33 ± 1.253
0.666PheCys: 0.666 ± 0.479
2.665PheAsp: 2.665 ± 0.586
1.999PheGlu: 1.999 ± 0.954
2.665PhePhe: 2.665 ± 1.56
1.999PheGly: 1.999 ± 0.835
0.333PheHis: 0.333 ± 0.294
0.999PheIle: 0.999 ± 0.503
0.999PheLys: 0.999 ± 0.44
3.331PheLeu: 3.331 ± 0.949
1.332PheMet: 1.332 ± 0.619
0.666PheAsn: 0.666 ± 0.384
0.666PhePro: 0.666 ± 0.65
0.999PheGln: 0.999 ± 0.507
2.665PheArg: 2.665 ± 0.93
3.331PheSer: 3.331 ± 0.912
1.666PheThr: 1.666 ± 0.555
3.331PheVal: 3.331 ± 0.934
0.666PheTrp: 0.666 ± 0.588
0.999PheTyr: 0.999 ± 0.522
0.0PheXaa: 0.0 ± 0.0
Gly
4.664GlyAla: 4.664 ± 1.323
2.332GlyCys: 2.332 ± 1.474
6.995GlyAsp: 6.995 ± 2.905
4.664GlyGlu: 4.664 ± 0.885
2.998GlyPhe: 2.998 ± 1.13
13.658GlyGly: 13.658 ± 8.848
1.332GlyHis: 1.332 ± 0.703
1.999GlyIle: 1.999 ± 0.617
4.664GlyLys: 4.664 ± 1.294
6.329GlyLeu: 6.329 ± 1.663
0.999GlyMet: 0.999 ± 0.503
3.997GlyAsn: 3.997 ± 1.548
2.998GlyPro: 2.998 ± 1.302
2.332GlyGln: 2.332 ± 0.941
5.996GlyArg: 5.996 ± 1.612
6.662GlySer: 6.662 ± 1.705
3.997GlyThr: 3.997 ± 1.705
4.33GlyVal: 4.33 ± 1.352
2.332GlyTrp: 2.332 ± 0.983
5.33GlyTyr: 5.33 ± 1.006
0.0GlyXaa: 0.0 ± 0.0
His
2.665HisAla: 2.665 ± 1.178
0.999HisCys: 0.999 ± 0.645
0.333HisAsp: 0.333 ± 0.325
0.333HisGlu: 0.333 ± 0.405
0.999HisPhe: 0.999 ± 0.61
0.999HisGly: 0.999 ± 0.555
0.999HisHis: 0.999 ± 0.572
1.332HisIle: 1.332 ± 0.683
1.332HisLys: 1.332 ± 0.65
1.666HisLeu: 1.666 ± 0.76
0.0HisMet: 0.0 ± 0.0
0.333HisAsn: 0.333 ± 0.294
2.665HisPro: 2.665 ± 1.132
0.999HisGln: 0.999 ± 0.554
1.332HisArg: 1.332 ± 0.647
1.666HisSer: 1.666 ± 0.6
0.333HisThr: 0.333 ± 0.303
2.332HisVal: 2.332 ± 0.9
0.333HisTrp: 0.333 ± 0.41
0.333HisTyr: 0.333 ± 0.294
0.0HisXaa: 0.0 ± 0.0
Ile
4.664IleAla: 4.664 ± 1.427
0.333IleCys: 0.333 ± 0.251
3.664IleAsp: 3.664 ± 1.413
4.997IleGlu: 4.997 ± 1.989
0.999IlePhe: 0.999 ± 0.411
3.664IleGly: 3.664 ± 1.639
1.666IleHis: 1.666 ± 0.564
1.999IleIle: 1.999 ± 1.153
3.664IleLys: 3.664 ± 0.674
3.997IleLeu: 3.997 ± 0.882
0.666IleMet: 0.666 ± 0.5
1.666IleAsn: 1.666 ± 0.972
2.665IlePro: 2.665 ± 0.515
1.999IleGln: 1.999 ± 1.029
2.665IleArg: 2.665 ± 0.947
4.33IleSer: 4.33 ± 1.529
1.999IleThr: 1.999 ± 0.676
2.998IleVal: 2.998 ± 1.207
0.666IleTrp: 0.666 ± 0.479
1.999IleTyr: 1.999 ± 0.526
0.0IleXaa: 0.0 ± 0.0
Lys
4.997LysAla: 4.997 ± 0.996
0.0LysCys: 0.0 ± 0.0
1.999LysAsp: 1.999 ± 0.763
2.665LysGlu: 2.665 ± 0.906
1.666LysPhe: 1.666 ± 0.627
5.33LysGly: 5.33 ± 0.901
0.999LysHis: 0.999 ± 0.666
2.332LysIle: 2.332 ± 0.502
1.666LysLys: 1.666 ± 0.633
3.997LysLeu: 3.997 ± 1.494
1.666LysMet: 1.666 ± 0.881
0.999LysAsn: 0.999 ± 0.38
3.664LysPro: 3.664 ± 0.995
1.999LysGln: 1.999 ± 0.803
2.332LysArg: 2.332 ± 0.869
3.331LysSer: 3.331 ± 1.15
4.664LysThr: 4.664 ± 0.848
2.998LysVal: 2.998 ± 0.742
0.0LysTrp: 0.0 ± 0.0
1.332LysTyr: 1.332 ± 0.741
0.0LysXaa: 0.0 ± 0.0
Leu
9.993LeuAla: 9.993 ± 2.066
1.999LeuCys: 1.999 ± 0.743
5.33LeuAsp: 5.33 ± 1.385
5.33LeuGlu: 5.33 ± 1.56
3.997LeuPhe: 3.997 ± 0.885
4.33LeuGly: 4.33 ± 1.563
2.332LeuHis: 2.332 ± 1.054
6.329LeuIle: 6.329 ± 1.925
2.998LeuLys: 2.998 ± 0.791
11.326LeuLeu: 11.326 ± 2.206
2.332LeuMet: 2.332 ± 1.021
3.331LeuAsn: 3.331 ± 0.751
5.663LeuPro: 5.663 ± 1.296
4.664LeuGln: 4.664 ± 1.686
6.995LeuArg: 6.995 ± 1.926
4.664LeuSer: 4.664 ± 1.468
5.663LeuThr: 5.663 ± 1.72
5.663LeuVal: 5.663 ± 1.237
0.999LeuTrp: 0.999 ± 0.455
0.999LeuTyr: 0.999 ± 0.633
0.0LeuXaa: 0.0 ± 0.0
Met
2.998MetAla: 2.998 ± 0.707
0.666MetCys: 0.666 ± 0.378
0.333MetAsp: 0.333 ± 0.329
1.332MetGlu: 1.332 ± 0.965
1.666MetPhe: 1.666 ± 0.728
2.998MetGly: 2.998 ± 0.926
0.333MetHis: 0.333 ± 0.294
0.999MetIle: 0.999 ± 0.693
1.666MetLys: 1.666 ± 1.04
1.332MetLeu: 1.332 ± 0.837
0.333MetMet: 0.333 ± 0.303
0.666MetAsn: 0.666 ± 0.471
0.333MetPro: 0.333 ± 0.325
0.0MetGln: 0.0 ± 0.0
1.666MetArg: 1.666 ± 0.631
2.332MetSer: 2.332 ± 0.729
1.999MetThr: 1.999 ± 0.583
0.999MetVal: 0.999 ± 0.634
0.0MetTrp: 0.0 ± 0.0
0.666MetTyr: 0.666 ± 0.835
0.0MetXaa: 0.0 ± 0.0
Asn
1.666AsnAla: 1.666 ± 0.609
0.999AsnCys: 0.999 ± 0.436
1.666AsnAsp: 1.666 ± 0.937
1.332AsnGlu: 1.332 ± 0.754
0.333AsnPhe: 0.333 ± 0.307
3.997AsnGly: 3.997 ± 1.288
0.333AsnHis: 0.333 ± 0.294
3.664AsnIle: 3.664 ± 0.836
0.666AsnLys: 0.666 ± 0.354
3.331AsnLeu: 3.331 ± 1.183
0.666AsnMet: 0.666 ± 0.406
1.332AsnAsn: 1.332 ± 0.616
2.665AsnPro: 2.665 ± 1.288
0.999AsnGln: 0.999 ± 0.38
0.999AsnArg: 0.999 ± 0.5
1.999AsnSer: 1.999 ± 0.922
1.666AsnThr: 1.666 ± 0.431
0.999AsnVal: 0.999 ± 0.541
0.666AsnTrp: 0.666 ± 0.493
0.666AsnTyr: 0.666 ± 0.347
0.0AsnXaa: 0.0 ± 0.0
Pro
8.328ProAla: 8.328 ± 2.192
0.333ProCys: 0.333 ± 0.307
4.664ProAsp: 4.664 ± 1.375
2.998ProGlu: 2.998 ± 1.377
1.999ProPhe: 1.999 ± 0.961
4.997ProGly: 4.997 ± 2.546
1.332ProHis: 1.332 ± 0.647
3.664ProIle: 3.664 ± 1.32
2.332ProLys: 2.332 ± 1.035
4.33ProLeu: 4.33 ± 1.905
1.332ProMet: 1.332 ± 0.841
1.999ProAsn: 1.999 ± 0.849
5.996ProPro: 5.996 ± 2.153
1.666ProGln: 1.666 ± 1.258
4.33ProArg: 4.33 ± 0.939
2.998ProSer: 2.998 ± 0.914
4.664ProThr: 4.664 ± 1.966
3.664ProVal: 3.664 ± 1.082
1.332ProTrp: 1.332 ± 0.743
0.333ProTyr: 0.333 ± 0.251
0.0ProXaa: 0.0 ± 0.0
Gln
4.664GlnAla: 4.664 ± 1.895
0.0GlnCys: 0.0 ± 0.0
3.664GlnAsp: 3.664 ± 0.841
1.332GlnGlu: 1.332 ± 0.838
0.999GlnPhe: 0.999 ± 0.645
3.331GlnGly: 3.331 ± 1.287
0.666GlnHis: 0.666 ± 0.398
1.666GlnIle: 1.666 ± 0.675
1.999GlnLys: 1.999 ± 0.678
4.33GlnLeu: 4.33 ± 0.931
0.666GlnMet: 0.666 ± 0.479
0.666GlnAsn: 0.666 ± 0.439
1.999GlnPro: 1.999 ± 1.166
1.999GlnGln: 1.999 ± 0.693
1.999GlnArg: 1.999 ± 0.977
0.666GlnSer: 0.666 ± 0.471
1.666GlnThr: 1.666 ± 0.646
1.332GlnVal: 1.332 ± 0.679
0.999GlnTrp: 0.999 ± 0.507
0.333GlnTyr: 0.333 ± 0.307
0.0GlnXaa: 0.0 ± 0.0
Arg
4.33ArgAla: 4.33 ± 1.349
0.666ArgCys: 0.666 ± 0.446
3.331ArgAsp: 3.331 ± 1.098
4.33ArgGlu: 4.33 ± 1.04
2.998ArgPhe: 2.998 ± 1.051
3.331ArgGly: 3.331 ± 0.796
2.665ArgHis: 2.665 ± 0.914
3.331ArgIle: 3.331 ± 1.181
5.996ArgLys: 5.996 ± 1.398
3.331ArgLeu: 3.331 ± 1.374
2.665ArgMet: 2.665 ± 0.704
1.332ArgAsn: 1.332 ± 0.51
4.664ArgPro: 4.664 ± 1.722
2.665ArgGln: 2.665 ± 0.883
5.33ArgArg: 5.33 ± 2.099
4.997ArgSer: 4.997 ± 1.495
2.332ArgThr: 2.332 ± 0.564
3.997ArgVal: 3.997 ± 0.666
1.332ArgTrp: 1.332 ± 0.965
2.332ArgTyr: 2.332 ± 0.751
0.0ArgXaa: 0.0 ± 0.0
Ser
4.997SerAla: 4.997 ± 1.277
0.666SerCys: 0.666 ± 0.472
1.666SerAsp: 1.666 ± 0.937
2.998SerGlu: 2.998 ± 1.163
3.331SerPhe: 3.331 ± 1.205
7.995SerGly: 7.995 ± 1.258
2.332SerHis: 2.332 ± 1.089
3.997SerIle: 3.997 ± 1.165
2.665SerLys: 2.665 ± 1.133
6.329SerLeu: 6.329 ± 1.101
1.332SerMet: 1.332 ± 1.006
2.665SerAsn: 2.665 ± 0.933
4.33SerPro: 4.33 ± 1.043
1.332SerGln: 1.332 ± 0.491
2.332SerArg: 2.332 ± 0.792
3.331SerSer: 3.331 ± 0.819
1.999SerThr: 1.999 ± 0.872
4.997SerVal: 4.997 ± 1.012
0.999SerTrp: 0.999 ± 0.661
2.665SerTyr: 2.665 ± 1.108
0.0SerXaa: 0.0 ± 0.0
Thr
4.664ThrAla: 4.664 ± 1.339
1.666ThrCys: 1.666 ± 0.738
3.331ThrAsp: 3.331 ± 1.025
1.999ThrGlu: 1.999 ± 0.699
0.999ThrPhe: 0.999 ± 0.447
5.33ThrGly: 5.33 ± 1.687
1.666ThrHis: 1.666 ± 0.898
2.332ThrIle: 2.332 ± 0.856
2.998ThrLys: 2.998 ± 1.465
5.996ThrLeu: 5.996 ± 1.55
0.999ThrMet: 0.999 ± 0.703
1.666ThrAsn: 1.666 ± 0.4
3.331ThrPro: 3.331 ± 1.125
1.999ThrGln: 1.999 ± 0.856
2.665ThrArg: 2.665 ± 0.779
3.664ThrSer: 3.664 ± 1.278
2.665ThrThr: 2.665 ± 1.358
2.332ThrVal: 2.332 ± 1.047
0.999ThrTrp: 0.999 ± 0.635
1.666ThrTyr: 1.666 ± 0.693
0.0ThrXaa: 0.0 ± 0.0
Val
7.328ValAla: 7.328 ± 1.902
0.999ValCys: 0.999 ± 0.572
2.665ValAsp: 2.665 ± 0.781
3.664ValGlu: 3.664 ± 1.19
0.666ValPhe: 0.666 ± 0.471
2.665ValGly: 2.665 ± 1.114
0.333ValHis: 0.333 ± 0.294
3.331ValIle: 3.331 ± 1.035
1.666ValLys: 1.666 ± 0.727
5.663ValLeu: 5.663 ± 1.057
1.666ValMet: 1.666 ± 0.814
2.332ValAsn: 2.332 ± 0.818
4.664ValPro: 4.664 ± 1.974
1.999ValGln: 1.999 ± 0.967
6.329ValArg: 6.329 ± 1.12
3.331ValSer: 3.331 ± 0.852
2.998ValThr: 2.998 ± 0.797
3.331ValVal: 3.331 ± 0.942
0.666ValTrp: 0.666 ± 0.588
1.666ValTyr: 1.666 ± 0.66
0.0ValXaa: 0.0 ± 0.0
Trp
1.332TrpAla: 1.332 ± 0.657
0.0TrpCys: 0.0 ± 0.0
1.332TrpAsp: 1.332 ± 0.485
1.332TrpGlu: 1.332 ± 0.537
0.666TrpPhe: 0.666 ± 0.533
1.666TrpGly: 1.666 ± 0.688
0.333TrpHis: 0.333 ± 0.294
1.332TrpIle: 1.332 ± 1.035
0.333TrpLys: 0.333 ± 0.294
1.332TrpLeu: 1.332 ± 0.637
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.666TrpPro: 0.666 ± 0.416
0.666TrpGln: 0.666 ± 0.605
1.666TrpArg: 1.666 ± 0.686
0.999TrpSer: 0.999 ± 0.38
1.999TrpThr: 1.999 ± 0.845
1.332TrpVal: 1.332 ± 0.712
0.333TrpTrp: 0.333 ± 0.41
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.331TyrAla: 3.331 ± 0.958
0.666TyrCys: 0.666 ± 0.347
1.332TyrAsp: 1.332 ± 0.671
0.666TyrGlu: 0.666 ± 0.354
0.333TyrPhe: 0.333 ± 0.251
1.999TyrGly: 1.999 ± 0.489
0.0TyrHis: 0.0 ± 0.0
0.999TyrIle: 0.999 ± 0.518
1.999TyrLys: 1.999 ± 1.204
4.997TyrLeu: 4.997 ± 1.436
1.666TyrMet: 1.666 ± 0.909
1.332TyrAsn: 1.332 ± 0.677
1.666TyrPro: 1.666 ± 0.56
0.666TyrGln: 0.666 ± 0.65
1.666TyrArg: 1.666 ± 0.595
2.332TyrSer: 2.332 ± 1.089
0.666TyrThr: 0.666 ± 0.594
0.666TyrVal: 0.666 ± 0.539
0.999TyrTrp: 0.999 ± 0.38
0.666TyrTyr: 0.666 ± 0.378
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 16 proteins (3003 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski