Amino acid dipepetide frequency for Pseudomonas phage PB1 (isolate Pseudomonas aeruginosa/Scotland/Bradley/1968) (PB1) (Bacteriophage PB1)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
10.963AlaAla: 10.963 ± 0.718
0.889AlaCys: 0.889 ± 0.234
5.333AlaAsp: 5.333 ± 0.555
8.543AlaGlu: 8.543 ± 1.118
3.556AlaPhe: 3.556 ± 0.373
7.358AlaGly: 7.358 ± 0.604
1.235AlaHis: 1.235 ± 0.286
6.321AlaIle: 6.321 ± 0.616
5.926AlaLys: 5.926 ± 0.65
7.062AlaLeu: 7.062 ± 0.648
2.272AlaMet: 2.272 ± 0.331
4.346AlaAsn: 4.346 ± 0.571
4.494AlaPro: 4.494 ± 0.566
4.099AlaGln: 4.099 ± 0.429
6.222AlaArg: 6.222 ± 0.571
6.123AlaSer: 6.123 ± 0.531
5.185AlaThr: 5.185 ± 0.59
5.827AlaVal: 5.827 ± 0.571
1.284AlaTrp: 1.284 ± 0.234
2.765AlaTyr: 2.765 ± 0.449
0.0AlaXaa: 0.0 ± 0.0
Cys
0.79CysAla: 0.79 ± 0.193
0.198CysCys: 0.198 ± 0.093
0.642CysAsp: 0.642 ± 0.162
0.593CysGlu: 0.593 ± 0.191
0.543CysPhe: 0.543 ± 0.162
0.494CysGly: 0.494 ± 0.154
0.099CysHis: 0.099 ± 0.069
0.395CysIle: 0.395 ± 0.128
0.444CysLys: 0.444 ± 0.179
0.691CysLeu: 0.691 ± 0.195
0.148CysMet: 0.148 ± 0.093
0.444CysAsn: 0.444 ± 0.156
0.691CysPro: 0.691 ± 0.162
0.049CysGln: 0.049 ± 0.05
0.642CysArg: 0.642 ± 0.215
0.346CysSer: 0.346 ± 0.125
0.741CysThr: 0.741 ± 0.2
0.741CysVal: 0.741 ± 0.171
0.198CysTrp: 0.198 ± 0.111
0.346CysTyr: 0.346 ± 0.147
0.0CysXaa: 0.0 ± 0.0
Asp
4.938AspAla: 4.938 ± 0.514
0.543AspCys: 0.543 ± 0.133
3.654AspAsp: 3.654 ± 0.607
5.037AspGlu: 5.037 ± 0.63
3.062AspPhe: 3.062 ± 0.418
6.963AspGly: 6.963 ± 0.577
1.284AspHis: 1.284 ± 0.26
3.556AspIle: 3.556 ± 0.602
2.963AspLys: 2.963 ± 0.457
5.037AspLeu: 5.037 ± 0.602
1.63AspMet: 1.63 ± 0.25
1.63AspAsn: 1.63 ± 0.288
3.951AspPro: 3.951 ± 0.436
2.272AspGln: 2.272 ± 0.346
3.309AspArg: 3.309 ± 0.52
3.704AspSer: 3.704 ± 0.474
2.765AspThr: 2.765 ± 0.388
3.309AspVal: 3.309 ± 0.434
1.432AspTrp: 1.432 ± 0.227
1.63AspTyr: 1.63 ± 0.329
0.0AspXaa: 0.0 ± 0.0
Glu
8.296GluAla: 8.296 ± 0.888
0.494GluCys: 0.494 ± 0.163
3.951GluAsp: 3.951 ± 0.534
6.074GluGlu: 6.074 ± 0.949
3.062GluPhe: 3.062 ± 0.372
4.049GluGly: 4.049 ± 0.755
1.975GluHis: 1.975 ± 0.421
4.247GluIle: 4.247 ± 0.53
4.543GluLys: 4.543 ± 0.763
6.42GluLeu: 6.42 ± 0.655
2.173GluMet: 2.173 ± 0.396
1.975GluAsn: 1.975 ± 0.337
2.963GluPro: 2.963 ± 0.366
2.914GluGln: 2.914 ± 0.409
4.889GluArg: 4.889 ± 0.695
3.16GluSer: 3.16 ± 0.387
3.062GluThr: 3.062 ± 0.41
4.444GluVal: 4.444 ± 0.42
0.889GluTrp: 0.889 ± 0.197
2.173GluTyr: 2.173 ± 0.345
0.0GluXaa: 0.0 ± 0.0
Phe
3.951PheAla: 3.951 ± 0.564
0.247PheCys: 0.247 ± 0.098
3.704PheAsp: 3.704 ± 0.513
2.864PheGlu: 2.864 ± 0.406
1.333PhePhe: 1.333 ± 0.296
3.654PheGly: 3.654 ± 0.336
0.593PheHis: 0.593 ± 0.173
2.42PheIle: 2.42 ± 0.312
1.63PheLys: 1.63 ± 0.358
2.963PheLeu: 2.963 ± 0.379
1.086PheMet: 1.086 ± 0.238
2.123PheAsn: 2.123 ± 0.321
1.432PhePro: 1.432 ± 0.232
1.481PheGln: 1.481 ± 0.264
2.173PheArg: 2.173 ± 0.369
2.272PheSer: 2.272 ± 0.37
1.926PheThr: 1.926 ± 0.326
2.667PheVal: 2.667 ± 0.388
0.691PheTrp: 0.691 ± 0.195
1.136PheTyr: 1.136 ± 0.189
0.0PheXaa: 0.0 ± 0.0
Gly
6.173GlyAla: 6.173 ± 0.682
0.593GlyCys: 0.593 ± 0.21
4.444GlyAsp: 4.444 ± 0.435
5.481GlyGlu: 5.481 ± 0.533
3.062GlyPhe: 3.062 ± 0.398
4.593GlyGly: 4.593 ± 0.661
1.037GlyHis: 1.037 ± 0.221
4.691GlyIle: 4.691 ± 0.42
3.259GlyLys: 3.259 ± 0.423
4.988GlyLeu: 4.988 ± 0.551
1.877GlyMet: 1.877 ± 0.28
2.864GlyAsn: 2.864 ± 0.629
2.815GlyPro: 2.815 ± 0.358
2.765GlyGln: 2.765 ± 0.38
5.136GlyArg: 5.136 ± 0.457
5.086GlySer: 5.086 ± 0.676
4.296GlyThr: 4.296 ± 0.49
5.136GlyVal: 5.136 ± 0.522
2.025GlyTrp: 2.025 ± 0.325
2.173GlyTyr: 2.173 ± 0.279
0.0GlyXaa: 0.0 ± 0.0
His
1.383HisAla: 1.383 ± 0.261
0.099HisCys: 0.099 ± 0.059
0.84HisAsp: 0.84 ± 0.196
1.63HisGlu: 1.63 ± 0.335
0.593HisPhe: 0.593 ± 0.134
1.679HisGly: 1.679 ± 0.318
0.395HisHis: 0.395 ± 0.144
1.037HisIle: 1.037 ± 0.285
0.79HisLys: 0.79 ± 0.225
0.988HisLeu: 0.988 ± 0.22
0.642HisMet: 0.642 ± 0.16
0.444HisAsn: 0.444 ± 0.146
0.84HisPro: 0.84 ± 0.205
0.593HisGln: 0.593 ± 0.165
1.63HisArg: 1.63 ± 0.33
0.988HisSer: 0.988 ± 0.229
0.691HisThr: 0.691 ± 0.18
0.84HisVal: 0.84 ± 0.204
0.247HisTrp: 0.247 ± 0.104
0.593HisTyr: 0.593 ± 0.169
0.0HisXaa: 0.0 ± 0.0
Ile
5.383IleAla: 5.383 ± 0.526
0.642IleCys: 0.642 ± 0.202
4.148IleAsp: 4.148 ± 0.518
3.704IleGlu: 3.704 ± 0.438
2.074IlePhe: 2.074 ± 0.319
4.049IleGly: 4.049 ± 0.525
1.284IleHis: 1.284 ± 0.223
3.753IleIle: 3.753 ± 0.472
2.963IleLys: 2.963 ± 0.503
4.346IleLeu: 4.346 ± 0.502
2.173IleMet: 2.173 ± 0.341
3.21IleAsn: 3.21 ± 0.384
3.605IlePro: 3.605 ± 0.429
2.716IleGln: 2.716 ± 0.35
3.802IleArg: 3.802 ± 0.476
4.247IleSer: 4.247 ± 0.475
3.259IleThr: 3.259 ± 0.364
2.815IleVal: 2.815 ± 0.391
0.691IleTrp: 0.691 ± 0.198
1.728IleTyr: 1.728 ± 0.238
0.0IleXaa: 0.0 ± 0.0
Lys
7.259LysAla: 7.259 ± 0.928
0.346LysCys: 0.346 ± 0.156
3.21LysAsp: 3.21 ± 0.462
3.605LysGlu: 3.605 ± 0.608
1.877LysPhe: 1.877 ± 0.273
3.21LysGly: 3.21 ± 0.422
0.642LysHis: 0.642 ± 0.17
2.765LysIle: 2.765 ± 0.44
2.864LysLys: 2.864 ± 0.45
4.79LysLeu: 4.79 ± 0.531
1.432LysMet: 1.432 ± 0.285
1.926LysAsn: 1.926 ± 0.214
2.765LysPro: 2.765 ± 0.37
1.333LysGln: 1.333 ± 0.295
3.605LysArg: 3.605 ± 0.471
3.358LysSer: 3.358 ± 0.455
2.963LysThr: 2.963 ± 0.44
3.556LysVal: 3.556 ± 0.355
0.543LysTrp: 0.543 ± 0.167
1.383LysTyr: 1.383 ± 0.348
0.0LysXaa: 0.0 ± 0.0
Leu
7.753LeuAla: 7.753 ± 0.683
0.84LeuCys: 0.84 ± 0.22
5.284LeuAsp: 5.284 ± 0.606
5.975LeuGlu: 5.975 ± 0.694
2.123LeuPhe: 2.123 ± 0.298
4.691LeuGly: 4.691 ± 0.442
0.741LeuHis: 0.741 ± 0.246
4.0LeuIle: 4.0 ± 0.486
4.444LeuLys: 4.444 ± 0.473
5.136LeuLeu: 5.136 ± 0.547
1.531LeuMet: 1.531 ± 0.294
3.457LeuAsn: 3.457 ± 0.378
3.259LeuPro: 3.259 ± 0.471
2.716LeuGln: 2.716 ± 0.41
4.84LeuArg: 4.84 ± 0.478
5.778LeuSer: 5.778 ± 0.542
3.704LeuThr: 3.704 ± 0.323
5.333LeuVal: 5.333 ± 0.564
1.235LeuTrp: 1.235 ± 0.231
2.222LeuTyr: 2.222 ± 0.388
0.0LeuXaa: 0.0 ± 0.0
Met
2.42MetAla: 2.42 ± 0.383
0.198MetCys: 0.198 ± 0.086
1.481MetAsp: 1.481 ± 0.278
1.778MetGlu: 1.778 ± 0.294
1.136MetPhe: 1.136 ± 0.232
1.136MetGly: 1.136 ± 0.235
0.296MetHis: 0.296 ± 0.139
1.728MetIle: 1.728 ± 0.264
1.481MetLys: 1.481 ± 0.285
1.877MetLeu: 1.877 ± 0.263
0.247MetMet: 0.247 ± 0.102
0.988MetAsn: 0.988 ± 0.205
0.938MetPro: 0.938 ± 0.231
0.84MetGln: 0.84 ± 0.242
1.778MetArg: 1.778 ± 0.344
2.321MetSer: 2.321 ± 0.318
1.877MetThr: 1.877 ± 0.267
1.531MetVal: 1.531 ± 0.273
0.148MetTrp: 0.148 ± 0.121
0.79MetTyr: 0.79 ± 0.131
0.0MetXaa: 0.0 ± 0.0
Asn
4.049AsnAla: 4.049 ± 0.672
0.247AsnCys: 0.247 ± 0.11
2.469AsnAsp: 2.469 ± 0.36
2.025AsnGlu: 2.025 ± 0.257
1.63AsnPhe: 1.63 ± 0.346
3.556AsnGly: 3.556 ± 0.456
0.889AsnHis: 0.889 ± 0.189
2.272AsnIle: 2.272 ± 0.355
0.84AsnLys: 0.84 ± 0.178
3.506AsnLeu: 3.506 ± 0.373
1.086AsnMet: 1.086 ± 0.246
1.827AsnAsn: 1.827 ± 0.484
2.765AsnPro: 2.765 ± 0.348
1.679AsnGln: 1.679 ± 0.325
2.37AsnArg: 2.37 ± 0.344
3.259AsnSer: 3.259 ± 0.41
1.975AsnThr: 1.975 ± 0.525
3.062AsnVal: 3.062 ± 0.596
0.691AsnTrp: 0.691 ± 0.156
1.284AsnTyr: 1.284 ± 0.285
0.0AsnXaa: 0.0 ± 0.0
Pro
4.642ProAla: 4.642 ± 0.624
0.247ProCys: 0.247 ± 0.128
3.506ProAsp: 3.506 ± 0.398
4.0ProGlu: 4.0 ± 0.516
2.173ProPhe: 2.173 ± 0.32
3.654ProGly: 3.654 ± 0.408
0.741ProHis: 0.741 ± 0.181
2.025ProIle: 2.025 ± 0.293
1.975ProLys: 1.975 ± 0.426
2.321ProLeu: 2.321 ± 0.289
1.185ProMet: 1.185 ± 0.239
2.123ProAsn: 2.123 ± 0.353
2.272ProPro: 2.272 ± 0.456
2.074ProGln: 2.074 ± 0.262
2.123ProArg: 2.123 ± 0.327
3.309ProSer: 3.309 ± 0.335
2.667ProThr: 2.667 ± 0.341
3.012ProVal: 3.012 ± 0.345
0.642ProTrp: 0.642 ± 0.213
1.136ProTyr: 1.136 ± 0.253
0.0ProXaa: 0.0 ± 0.0
Gln
3.605GlnAla: 3.605 ± 0.424
0.543GlnCys: 0.543 ± 0.185
2.123GlnAsp: 2.123 ± 0.338
2.37GlnGlu: 2.37 ± 0.357
2.074GlnPhe: 2.074 ± 0.345
2.469GlnGly: 2.469 ± 0.463
0.593GlnHis: 0.593 ± 0.15
2.42GlnIle: 2.42 ± 0.351
2.469GlnLys: 2.469 ± 0.348
3.21GlnLeu: 3.21 ± 0.32
0.741GlnMet: 0.741 ± 0.185
2.321GlnAsn: 2.321 ± 0.418
1.63GlnPro: 1.63 ± 0.276
1.432GlnGln: 1.432 ± 0.24
2.173GlnArg: 2.173 ± 0.336
1.926GlnSer: 1.926 ± 0.305
2.42GlnThr: 2.42 ± 0.383
2.222GlnVal: 2.222 ± 0.375
0.395GlnTrp: 0.395 ± 0.147
1.086GlnTyr: 1.086 ± 0.235
0.0GlnXaa: 0.0 ± 0.0
Arg
5.778ArgAla: 5.778 ± 0.667
0.593ArgCys: 0.593 ± 0.177
3.704ArgAsp: 3.704 ± 0.415
4.296ArgGlu: 4.296 ± 0.563
2.519ArgPhe: 2.519 ± 0.349
3.654ArgGly: 3.654 ± 0.386
1.383ArgHis: 1.383 ± 0.263
4.79ArgIle: 4.79 ± 0.456
4.049ArgLys: 4.049 ± 0.477
5.877ArgLeu: 5.877 ± 0.581
1.531ArgMet: 1.531 ± 0.278
2.272ArgAsn: 2.272 ± 0.311
2.321ArgPro: 2.321 ± 0.299
2.617ArgGln: 2.617 ± 0.307
4.148ArgArg: 4.148 ± 0.501
3.16ArgSer: 3.16 ± 0.385
2.716ArgThr: 2.716 ± 0.422
3.753ArgVal: 3.753 ± 0.485
0.84ArgTrp: 0.84 ± 0.2
2.222ArgTyr: 2.222 ± 0.366
0.0ArgXaa: 0.0 ± 0.0
Ser
7.062SerAla: 7.062 ± 0.669
0.494SerCys: 0.494 ± 0.177
3.654SerAsp: 3.654 ± 0.336
3.457SerGlu: 3.457 ± 0.435
2.617SerPhe: 2.617 ± 0.491
4.198SerGly: 4.198 ± 0.646
1.235SerHis: 1.235 ± 0.288
3.951SerIle: 3.951 ± 0.483
3.556SerLys: 3.556 ± 0.392
4.444SerLeu: 4.444 ± 0.58
1.63SerMet: 1.63 ± 0.32
2.272SerAsn: 2.272 ± 0.44
2.914SerPro: 2.914 ± 0.38
2.568SerGln: 2.568 ± 0.406
3.901SerArg: 3.901 ± 0.383
4.84SerSer: 4.84 ± 0.596
3.556SerThr: 3.556 ± 0.479
4.593SerVal: 4.593 ± 0.476
0.988SerTrp: 0.988 ± 0.236
2.37SerTyr: 2.37 ± 0.32
0.0SerXaa: 0.0 ± 0.0
Thr
5.136ThrAla: 5.136 ± 0.452
0.494ThrCys: 0.494 ± 0.136
2.667ThrAsp: 2.667 ± 0.297
2.667ThrGlu: 2.667 ± 0.337
2.617ThrPhe: 2.617 ± 0.381
4.79ThrGly: 4.79 ± 0.615
0.741ThrHis: 0.741 ± 0.203
3.506ThrIle: 3.506 ± 0.494
3.16ThrLys: 3.16 ± 0.374
3.802ThrLeu: 3.802 ± 0.418
0.84ThrMet: 0.84 ± 0.191
1.877ThrAsn: 1.877 ± 0.383
2.864ThrPro: 2.864 ± 0.514
1.679ThrGln: 1.679 ± 0.277
2.716ThrArg: 2.716 ± 0.45
4.395ThrSer: 4.395 ± 0.473
2.716ThrThr: 2.716 ± 0.425
3.457ThrVal: 3.457 ± 0.448
0.691ThrTrp: 0.691 ± 0.212
1.235ThrTyr: 1.235 ± 0.247
0.0ThrXaa: 0.0 ± 0.0
Val
6.815ValAla: 6.815 ± 0.638
0.889ValCys: 0.889 ± 0.208
5.185ValAsp: 5.185 ± 0.449
4.938ValGlu: 4.938 ± 0.488
2.469ValPhe: 2.469 ± 0.436
4.346ValGly: 4.346 ± 0.451
1.086ValHis: 1.086 ± 0.265
3.654ValIle: 3.654 ± 0.521
3.753ValLys: 3.753 ± 0.416
4.049ValLeu: 4.049 ± 0.503
1.728ValMet: 1.728 ± 0.367
2.914ValAsn: 2.914 ± 0.49
2.025ValPro: 2.025 ± 0.348
2.765ValGln: 2.765 ± 0.373
3.654ValArg: 3.654 ± 0.48
3.407ValSer: 3.407 ± 0.379
3.506ValThr: 3.506 ± 0.423
4.84ValVal: 4.84 ± 0.564
0.938ValTrp: 0.938 ± 0.179
1.481ValTyr: 1.481 ± 0.295
0.0ValXaa: 0.0 ± 0.0
Trp
1.432TrpAla: 1.432 ± 0.232
0.198TrpCys: 0.198 ± 0.109
0.988TrpAsp: 0.988 ± 0.188
1.136TrpGlu: 1.136 ± 0.288
0.593TrpPhe: 0.593 ± 0.188
1.284TrpGly: 1.284 ± 0.306
0.148TrpHis: 0.148 ± 0.092
0.938TrpIle: 0.938 ± 0.238
1.037TrpLys: 1.037 ± 0.181
1.136TrpLeu: 1.136 ± 0.238
0.346TrpMet: 0.346 ± 0.133
1.086TrpAsn: 1.086 ± 0.232
0.543TrpPro: 0.543 ± 0.174
0.346TrpGln: 0.346 ± 0.141
0.988TrpArg: 0.988 ± 0.201
0.79TrpSer: 0.79 ± 0.179
0.642TrpThr: 0.642 ± 0.147
1.086TrpVal: 1.086 ± 0.188
0.198TrpTrp: 0.198 ± 0.102
0.444TrpTyr: 0.444 ± 0.136
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.975TyrAla: 1.975 ± 0.352
0.494TyrCys: 0.494 ± 0.171
1.679TyrAsp: 1.679 ± 0.287
1.58TyrGlu: 1.58 ± 0.301
1.235TyrPhe: 1.235 ± 0.212
2.667TyrGly: 2.667 ± 0.359
0.543TyrHis: 0.543 ± 0.154
2.123TyrIle: 2.123 ± 0.368
1.284TyrLys: 1.284 ± 0.248
2.42TyrLeu: 2.42 ± 0.356
0.642TyrMet: 0.642 ± 0.177
1.383TyrAsn: 1.383 ± 0.249
0.741TyrPro: 0.741 ± 0.175
1.284TyrGln: 1.284 ± 0.294
2.123TyrArg: 2.123 ± 0.317
1.827TyrSer: 1.827 ± 0.25
1.383TyrThr: 1.383 ± 0.223
2.222TyrVal: 2.222 ± 0.478
0.593TyrTrp: 0.593 ± 0.171
0.593TyrTyr: 0.593 ± 0.191
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 93 proteins (20251 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski