Amino acid dipepetide frequency for Zymoseptoria tritici ST99CH_3D7

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	10.055AlaAla: 10.055 ± 0.053	1.09AlaCys: 1.09 ± 0.015	4.655AlaAsp: 4.655 ± 0.034	5.779AlaGlu: 5.779 ± 0.044	3.199AlaPhe: 3.199 ± 0.027	6.325AlaGly: 6.325 ± 0.044	1.862AlaHis: 1.862 ± 0.019	4.165AlaIle: 4.165 ± 0.027	4.526AlaLys: 4.526 ± 0.033	7.835AlaLeu: 7.835 ± 0.044	2.185AlaMet: 2.185 ± 0.023	3.185AlaAsn: 3.185 ± 0.027	5.202AlaPro: 5.202 ± 0.046	3.752AlaGln: 3.752 ± 0.03	5.34AlaArg: 5.34 ± 0.038	7.651AlaSer: 7.651 ± 0.057	5.681AlaThr: 5.681 ± 0.039	5.645AlaVal: 5.645 ± 0.039	1.194AlaTrp: 1.194 ± 0.016	2.215AlaTyr: 2.215 ± 0.026	0.0AlaXaa: 0.0 ± 0.0
Cys	0.988CysAla: 0.988 ± 0.015	0.254CysCys: 0.254 ± 0.009	0.673CysAsp: 0.673 ± 0.011	0.624CysGlu: 0.624 ± 0.01	0.515CysPhe: 0.515 ± 0.011	0.955CysGly: 0.955 ± 0.016	0.324CysHis: 0.324 ± 0.008	0.649CysIle: 0.649 ± 0.01	0.54CysLys: 0.54 ± 0.01	1.15CysLeu: 1.15 ± 0.017	0.272CysMet: 0.272 ± 0.008	0.409CysAsn: 0.409 ± 0.01	0.643CysPro: 0.643 ± 0.013	0.433CysGln: 0.433 ± 0.009	0.745CysArg: 0.745 ± 0.012	0.876CysSer: 0.876 ± 0.015	0.722CysThr: 0.722 ± 0.013	0.779CysVal: 0.779 ± 0.013	0.186CysTrp: 0.186 ± 0.007	0.36CysTyr: 0.36 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	5.174AspAla: 5.174 ± 0.033	0.652AspCys: 0.652 ± 0.011	4.645AspAsp: 4.645 ± 0.048	4.787AspGlu: 4.787 ± 0.041	2.298AspPhe: 2.298 ± 0.022	4.425AspGly: 4.425 ± 0.031	1.323AspHis: 1.323 ± 0.018	2.779AspIle: 2.779 ± 0.023	2.299AspLys: 2.299 ± 0.025	5.126AspLeu: 5.126 ± 0.036	1.325AspMet: 1.325 ± 0.016	1.839AspAsn: 1.839 ± 0.019	3.246AspPro: 3.246 ± 0.028	1.963AspGln: 1.963 ± 0.019	3.156AspArg: 3.156 ± 0.03	4.113AspSer: 4.113 ± 0.033	3.001AspThr: 3.001 ± 0.023	3.879AspVal: 3.879 ± 0.028	0.902AspTrp: 0.902 ± 0.012	1.54AspTyr: 1.54 ± 0.017	0.0AspXaa: 0.0 ± 0.0
Glu	5.697GluAla: 5.697 ± 0.046	0.635GluCys: 0.635 ± 0.011	4.642GluAsp: 4.642 ± 0.039	5.92GluGlu: 5.92 ± 0.056	1.825GluPhe: 1.825 ± 0.019	4.119GluGly: 4.119 ± 0.036	1.488GluHis: 1.488 ± 0.017	2.809GluIle: 2.809 ± 0.021	3.799GluLys: 3.799 ± 0.04	5.23GluLeu: 5.23 ± 0.039	1.605GluMet: 1.605 ± 0.016	2.093GluAsn: 2.093 ± 0.021	2.693GluPro: 2.693 ± 0.031	2.767GluGln: 2.767 ± 0.029	4.189GluArg: 4.189 ± 0.039	4.054GluSer: 4.054 ± 0.034	3.401GluThr: 3.401 ± 0.03	3.996GluVal: 3.996 ± 0.03	0.917GluTrp: 0.917 ± 0.013	1.589GluTyr: 1.589 ± 0.019	0.0GluXaa: 0.0 ± 0.0
Phe	3.268PheAla: 3.268 ± 0.027	0.53PheCys: 0.53 ± 0.009	2.292PheAsp: 2.292 ± 0.023	2.125PheGlu: 2.125 ± 0.021	1.464PhePhe: 1.464 ± 0.021	2.832PheGly: 2.832 ± 0.026	0.86PheHis: 0.86 ± 0.012	1.562PheIle: 1.562 ± 0.018	1.445PheLys: 1.445 ± 0.016	3.13PheLeu: 3.13 ± 0.029	0.728PheMet: 0.728 ± 0.012	1.365PheAsn: 1.365 ± 0.017	1.795PhePro: 1.795 ± 0.019	1.283PheGln: 1.283 ± 0.017	1.862PheArg: 1.862 ± 0.021	2.721PheSer: 2.721 ± 0.025	2.161PheThr: 2.161 ± 0.022	2.293PheVal: 2.293 ± 0.023	0.607PheTrp: 0.607 ± 0.011	0.992PheTyr: 0.992 ± 0.015	0.0PheXaa: 0.0 ± 0.0
Gly	5.494GlyAla: 5.494 ± 0.042	0.866GlyCys: 0.866 ± 0.014	3.814GlyAsp: 3.814 ± 0.033	4.104GlyGlu: 4.104 ± 0.032	2.707GlyPhe: 2.707 ± 0.029	6.712GlyGly: 6.712 ± 0.066	1.678GlyHis: 1.678 ± 0.021	3.241GlyIle: 3.241 ± 0.024	3.722GlyLys: 3.722 ± 0.03	5.961GlyLeu: 5.961 ± 0.038	1.835GlyMet: 1.835 ± 0.019	2.571GlyAsn: 2.571 ± 0.028	3.258GlyPro: 3.258 ± 0.031	2.704GlyGln: 2.704 ± 0.027	4.328GlyArg: 4.328 ± 0.037	5.718GlySer: 5.718 ± 0.053	4.032GlyThr: 4.032 ± 0.032	4.454GlyVal: 4.454 ± 0.031	1.18GlyTrp: 1.18 ± 0.018	2.093GlyTyr: 2.093 ± 0.023	0.0GlyXaa: 0.0 ± 0.0
His	2.058HisAla: 2.058 ± 0.022	0.348HisCys: 0.348 ± 0.009	1.42HisAsp: 1.42 ± 0.018	1.371HisGlu: 1.371 ± 0.015	0.936HisPhe: 0.936 ± 0.013	1.721HisGly: 1.721 ± 0.019	0.851HisHis: 0.851 ± 0.016	1.142HisIle: 1.142 ± 0.016	0.906HisLys: 0.906 ± 0.013	2.231HisLeu: 2.231 ± 0.023	0.471HisMet: 0.471 ± 0.009	0.863HisAsn: 0.863 ± 0.013	1.611HisPro: 1.611 ± 0.022	0.982HisGln: 0.982 ± 0.014	1.514HisArg: 1.514 ± 0.02	1.801HisSer: 1.801 ± 0.02	1.322HisThr: 1.322 ± 0.017	1.402HisVal: 1.402 ± 0.017	0.355HisTrp: 0.355 ± 0.009	0.657HisTyr: 0.657 ± 0.011	0.0HisXaa: 0.0 ± 0.0
Ile	4.268IleAla: 4.268 ± 0.031	0.678IleCys: 0.678 ± 0.012	2.787IleAsp: 2.787 ± 0.023	2.766IleGlu: 2.766 ± 0.026	1.793IlePhe: 1.793 ± 0.021	3.041IleGly: 3.041 ± 0.028	1.083IleHis: 1.083 ± 0.016	2.121IleIle: 2.121 ± 0.024	2.024IleLys: 2.024 ± 0.023	4.009IleLeu: 4.009 ± 0.029	0.952IleMet: 0.952 ± 0.016	1.635IleAsn: 1.635 ± 0.019	2.791IlePro: 2.791 ± 0.03	1.614IleGln: 1.614 ± 0.016	2.585IleArg: 2.585 ± 0.024	3.532IleSer: 3.532 ± 0.027	2.743IleThr: 2.743 ± 0.022	2.997IleVal: 2.997 ± 0.024	0.643IleTrp: 0.643 ± 0.012	1.262IleTyr: 1.262 ± 0.019	0.0IleXaa: 0.0 ± 0.0
Lys	4.645LysAla: 4.645 ± 0.037	0.507LysCys: 0.507 ± 0.01	2.962LysAsp: 2.962 ± 0.028	3.478LysGlu: 3.478 ± 0.034	1.408LysPhe: 1.408 ± 0.018	3.047LysGly: 3.047 ± 0.027	1.156LysHis: 1.156 ± 0.015	2.099LysIle: 2.099 ± 0.024	3.506LysLys: 3.506 ± 0.052	3.969LysLeu: 3.969 ± 0.03	1.091LysMet: 1.091 ± 0.017	1.633LysAsn: 1.633 ± 0.021	2.728LysPro: 2.728 ± 0.026	1.974LysGln: 1.974 ± 0.022	3.571LysArg: 3.571 ± 0.033	3.534LysSer: 3.534 ± 0.031	2.87LysThr: 2.87 ± 0.027	2.918LysVal: 2.918 ± 0.025	0.678LysTrp: 0.678 ± 0.01	1.254LysTyr: 1.254 ± 0.015	0.0LysXaa: 0.0 ± 0.0
Leu	7.973LeuAla: 7.973 ± 0.038	1.128LeuCys: 1.128 ± 0.014	4.987LeuAsp: 4.987 ± 0.033	5.362LeuGlu: 5.362 ± 0.037	2.975LeuPhe: 2.975 ± 0.029	5.562LeuGly: 5.562 ± 0.036	2.23LeuHis: 2.23 ± 0.023	3.588LeuIle: 3.588 ± 0.03	4.107LeuLys: 4.107 ± 0.036	7.915LeuLeu: 7.915 ± 0.059	1.737LeuMet: 1.737 ± 0.016	2.965LeuAsn: 2.965 ± 0.024	5.602LeuPro: 5.602 ± 0.046	3.807LeuGln: 3.807 ± 0.032	5.717LeuArg: 5.717 ± 0.039	6.816LeuSer: 6.816 ± 0.045	4.845LeuThr: 4.845 ± 0.034	5.051LeuVal: 5.051 ± 0.033	1.13LeuTrp: 1.13 ± 0.017	2.152LeuTyr: 2.152 ± 0.023	0.0LeuXaa: 0.0 ± 0.0
Met	2.311MetAla: 2.311 ± 0.021	0.256MetCys: 0.256 ± 0.007	1.308MetAsp: 1.308 ± 0.015	1.363MetGlu: 1.363 ± 0.017	0.733MetPhe: 0.733 ± 0.011	1.5MetGly: 1.5 ± 0.019	0.517MetHis: 0.517 ± 0.01	0.945MetIle: 0.945 ± 0.014	1.067MetLys: 1.067 ± 0.014	1.908MetLeu: 1.908 ± 0.022	0.6MetMet: 0.6 ± 0.013	0.791MetAsn: 0.791 ± 0.014	1.42MetPro: 1.42 ± 0.018	0.976MetGln: 0.976 ± 0.017	1.385MetArg: 1.385 ± 0.016	1.924MetSer: 1.924 ± 0.019	1.281MetThr: 1.281 ± 0.018	1.27MetVal: 1.27 ± 0.014	0.268MetTrp: 0.268 ± 0.006	0.54MetTyr: 0.54 ± 0.009	0.0MetXaa: 0.0 ± 0.0
Asn	3.386AsnAla: 3.386 ± 0.026	0.421AsnCys: 0.421 ± 0.011	2.096AsnAsp: 2.096 ± 0.021	2.027AsnGlu: 2.027 ± 0.019	1.317AsnPhe: 1.317 ± 0.017	3.256AsnGly: 3.256 ± 0.034	0.819AsnHis: 0.819 ± 0.012	1.844AsnIle: 1.844 ± 0.019	1.493AsnLys: 1.493 ± 0.018	2.99AsnLeu: 2.99 ± 0.027	0.813AsnMet: 0.813 ± 0.011	1.476AsnAsn: 1.476 ± 0.024	2.274AsnPro: 2.274 ± 0.022	1.193AsnGln: 1.193 ± 0.019	1.845AsnArg: 1.845 ± 0.019	2.613AsnSer: 2.613 ± 0.027	2.243AsnThr: 2.243 ± 0.021	2.306AsnVal: 2.306 ± 0.02	0.507AsnTrp: 0.507 ± 0.011	0.97AsnTyr: 0.97 ± 0.014	0.0AsnXaa: 0.0 ± 0.0
Pro	5.826ProAla: 5.826 ± 0.051	0.527ProCys: 0.527 ± 0.012	3.124ProAsp: 3.124 ± 0.026	3.644ProGlu: 3.644 ± 0.033	1.933ProPhe: 1.933 ± 0.021	3.921ProGly: 3.921 ± 0.038	1.339ProHis: 1.339 ± 0.018	2.442ProIle: 2.442 ± 0.025	2.644ProLys: 2.644 ± 0.026	4.473ProLeu: 4.473 ± 0.032	1.107ProMet: 1.107 ± 0.016	2.181ProAsn: 2.181 ± 0.022	5.467ProPro: 5.467 ± 0.075	2.529ProGln: 2.529 ± 0.032	3.347ProArg: 3.347 ± 0.027	6.037ProSer: 6.037 ± 0.054	4.28ProThr: 4.28 ± 0.036	3.36ProVal: 3.36 ± 0.028	0.677ProTrp: 0.677 ± 0.013	1.431ProTyr: 1.431 ± 0.016	0.0ProXaa: 0.0 ± 0.0
Gln	3.753GlnAla: 3.753 ± 0.03	0.459GlnCys: 0.459 ± 0.01	2.204GlnAsp: 2.204 ± 0.023	2.381GlnGlu: 2.381 ± 0.025	1.205GlnPhe: 1.205 ± 0.017	2.397GlnGly: 2.397 ± 0.022	1.222GlnHis: 1.222 ± 0.017	1.782GlnIle: 1.782 ± 0.021	1.979GlnLys: 1.979 ± 0.023	3.352GlnLeu: 3.352 ± 0.03	0.913GlnMet: 0.913 ± 0.016	1.548GlnAsn: 1.548 ± 0.019	2.628GlnPro: 2.628 ± 0.032	2.802GlnGln: 2.802 ± 0.058	2.809GlnArg: 2.809 ± 0.025	3.215GlnSer: 3.215 ± 0.028	2.467GlnThr: 2.467 ± 0.024	2.139GlnVal: 2.139 ± 0.021	0.555GlnTrp: 0.555 ± 0.01	1.201GlnTyr: 1.201 ± 0.017	0.0GlnXaa: 0.0 ± 0.0
Arg	5.0ArgAla: 5.0 ± 0.038	0.73ArgCys: 0.73 ± 0.015	3.399ArgAsp: 3.399 ± 0.032	4.007ArgGlu: 4.007 ± 0.033	2.045ArgPhe: 2.045 ± 0.018	3.816ArgGly: 3.816 ± 0.039	1.536ArgHis: 1.536 ± 0.016	2.774ArgIle: 2.774 ± 0.022	3.666ArgLys: 3.666 ± 0.028	5.316ArgLeu: 5.316 ± 0.037	1.44ArgMet: 1.44 ± 0.017	2.259ArgAsn: 2.259 ± 0.02	3.617ArgPro: 3.617 ± 0.031	2.724ArgGln: 2.724 ± 0.025	5.112ArgArg: 5.112 ± 0.048	4.928ArgSer: 4.928 ± 0.037	3.559ArgThr: 3.559 ± 0.027	3.288ArgVal: 3.288 ± 0.025	0.916ArgTrp: 0.916 ± 0.015	1.555ArgTyr: 1.555 ± 0.018	0.0ArgXaa: 0.0 ± 0.0
Ser	7.144SerAla: 7.144 ± 0.05	0.832SerCys: 0.832 ± 0.014	4.309SerAsp: 4.309 ± 0.035	4.117SerGlu: 4.117 ± 0.033	2.763SerPhe: 2.763 ± 0.025	5.694SerGly: 5.694 ± 0.047	1.844SerHis: 1.844 ± 0.018	3.753SerIle: 3.753 ± 0.03	3.718SerLys: 3.718 ± 0.034	6.632SerLeu: 6.632 ± 0.04	1.769SerMet: 1.769 ± 0.018	3.065SerAsn: 3.065 ± 0.029	5.365SerPro: 5.365 ± 0.049	3.184SerGln: 3.184 ± 0.029	4.889SerArg: 4.889 ± 0.04	8.697SerSer: 8.697 ± 0.098	6.071SerThr: 6.071 ± 0.053	4.343SerVal: 4.343 ± 0.032	1.042SerTrp: 1.042 ± 0.016	1.942SerTyr: 1.942 ± 0.021	0.0SerXaa: 0.0 ± 0.0
Thr	5.845ThrAla: 5.845 ± 0.042	0.77ThrCys: 0.77 ± 0.013	2.923ThrAsp: 2.923 ± 0.025	3.096ThrGlu: 3.096 ± 0.028	2.323ThrPhe: 2.323 ± 0.022	4.213ThrGly: 4.213 ± 0.034	1.327ThrHis: 1.327 ± 0.017	3.086ThrIle: 3.086 ± 0.026	2.715ThrLys: 2.715 ± 0.023	5.277ThrLeu: 5.277 ± 0.036	1.275ThrMet: 1.275 ± 0.015	2.169ThrAsn: 2.169 ± 0.021	4.426ThrPro: 4.426 ± 0.04	2.169ThrGln: 2.169 ± 0.022	3.197ThrArg: 3.197 ± 0.027	5.757ThrSer: 5.757 ± 0.05	4.922ThrThr: 4.922 ± 0.064	3.637ThrVal: 3.637 ± 0.032	0.825ThrTrp: 0.825 ± 0.014	1.59ThrTyr: 1.59 ± 0.023	0.0ThrXaa: 0.0 ± 0.0
Val	5.365ValAla: 5.365 ± 0.035	0.799ValCys: 0.799 ± 0.012	3.717ValAsp: 3.717 ± 0.03	4.214ValGlu: 4.214 ± 0.032	2.277ValPhe: 2.277 ± 0.024	4.063ValGly: 4.063 ± 0.036	1.405ValHis: 1.405 ± 0.016	2.588ValIle: 2.588 ± 0.022	3.069ValLys: 3.069 ± 0.027	5.465ValLeu: 5.465 ± 0.037	1.32ValMet: 1.32 ± 0.014	2.151ValAsn: 2.151 ± 0.022	3.519ValPro: 3.519 ± 0.03	2.461ValGln: 2.461 ± 0.022	3.586ValArg: 3.586 ± 0.029	4.263ValSer: 4.263 ± 0.03	3.348ValThr: 3.348 ± 0.03	4.269ValVal: 4.269 ± 0.033	0.866ValTrp: 0.866 ± 0.014	1.613ValTyr: 1.613 ± 0.018	0.0ValXaa: 0.0 ± 0.0
Trp	1.078TrpAla: 1.078 ± 0.015	0.205TrpCys: 0.205 ± 0.007	0.842TrpAsp: 0.842 ± 0.012	0.829TrpGlu: 0.829 ± 0.014	0.509TrpPhe: 0.509 ± 0.01	0.814TrpGly: 0.814 ± 0.014	0.368TrpHis: 0.368 ± 0.008	0.706TrpIle: 0.706 ± 0.014	0.779TrpLys: 0.779 ± 0.012	1.305TrpLeu: 1.305 ± 0.019	0.366TrpMet: 0.366 ± 0.009	0.603TrpAsn: 0.603 ± 0.011	0.6TrpPro: 0.6 ± 0.01	0.627TrpGln: 0.627 ± 0.011	1.001TrpArg: 1.001 ± 0.015	1.06TrpSer: 1.06 ± 0.016	0.957TrpThr: 0.957 ± 0.014	0.815TrpVal: 0.815 ± 0.013	0.257TrpTrp: 0.257 ± 0.008	0.403TrpTyr: 0.403 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.212TyrAla: 2.212 ± 0.022	0.41TyrCys: 0.41 ± 0.009	1.672TyrAsp: 1.672 ± 0.019	1.477TyrGlu: 1.477 ± 0.018	1.091TyrPhe: 1.091 ± 0.016	2.061TyrGly: 2.061 ± 0.025	0.731TyrHis: 0.731 ± 0.012	1.25TyrIle: 1.25 ± 0.016	1.023TyrLys: 1.023 ± 0.014	2.372TyrLeu: 2.372 ± 0.023	0.558TyrMet: 0.558 ± 0.011	1.085TyrAsn: 1.085 ± 0.017	1.404TyrPro: 1.404 ± 0.021	1.069TyrGln: 1.069 ± 0.016	1.51TyrArg: 1.51 ± 0.016	1.863TyrSer: 1.863 ± 0.02	1.635TyrThr: 1.635 ± 0.018	1.517TyrVal: 1.517 ± 0.018	0.42TyrTrp: 0.42 ± 0.008	0.863TyrTyr: 0.863 ± 0.013	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 11722 proteins (5360897 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---