Amino acid dipepetide frequency for Defluviimonas alba

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	21.583AlaAla: 21.583 ± 0.203	1.201AlaCys: 1.201 ± 0.034	7.157AlaAsp: 7.157 ± 0.075	9.307AlaGlu: 9.307 ± 0.096	4.432AlaPhe: 4.432 ± 0.062	13.102AlaGly: 13.102 ± 0.123	2.382AlaHis: 2.382 ± 0.047	5.851AlaIle: 5.851 ± 0.069	3.185AlaLys: 3.185 ± 0.055	15.82AlaLeu: 15.82 ± 0.149	3.941AlaMet: 3.941 ± 0.05	2.451AlaAsn: 2.451 ± 0.037	7.2AlaPro: 7.2 ± 0.097	4.596AlaGln: 4.596 ± 0.066	10.83AlaArg: 10.83 ± 0.104	6.036AlaSer: 6.036 ± 0.075	6.25AlaThr: 6.25 ± 0.07	9.366AlaVal: 9.366 ± 0.094	1.631AlaTrp: 1.631 ± 0.033	2.449AlaTyr: 2.449 ± 0.043	0.0AlaXaa: 0.0 ± 0.0
Cys	1.156CysAla: 1.156 ± 0.032	0.164CysCys: 0.164 ± 0.013	0.54CysAsp: 0.54 ± 0.022	0.42CysGlu: 0.42 ± 0.019	0.305CysPhe: 0.305 ± 0.013	0.981CysGly: 0.981 ± 0.027	0.266CysHis: 0.266 ± 0.017	0.395CysIle: 0.395 ± 0.017	0.207CysLys: 0.207 ± 0.013	0.856CysLeu: 0.856 ± 0.026	0.187CysMet: 0.187 ± 0.012	0.193CysAsn: 0.193 ± 0.01	0.562CysPro: 0.562 ± 0.023	0.222CysGln: 0.222 ± 0.012	0.72CysArg: 0.72 ± 0.023	0.466CysSer: 0.466 ± 0.017	0.452CysThr: 0.452 ± 0.021	0.595CysVal: 0.595 ± 0.021	0.161CysTrp: 0.161 ± 0.012	0.172CysTyr: 0.172 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	6.85AspAla: 6.85 ± 0.081	0.51AspCys: 0.51 ± 0.018	2.687AspAsp: 2.687 ± 0.052	2.983AspGlu: 2.983 ± 0.053	2.029AspPhe: 2.029 ± 0.037	4.968AspGly: 4.968 ± 0.069	1.295AspHis: 1.295 ± 0.034	2.603AspIle: 2.603 ± 0.046	1.285AspLys: 1.285 ± 0.029	6.454AspLeu: 6.454 ± 0.077	1.425AspMet: 1.425 ± 0.032	0.959AspAsn: 0.959 ± 0.027	3.793AspPro: 3.793 ± 0.061	1.612AspGln: 1.612 ± 0.03	4.477AspArg: 4.477 ± 0.064	1.94AspSer: 1.94 ± 0.036	2.521AspThr: 2.521 ± 0.048	3.541AspVal: 3.541 ± 0.059	1.189AspTrp: 1.189 ± 0.03	1.37AspTyr: 1.37 ± 0.031	0.0AspXaa: 0.0 ± 0.0
Glu	8.808GluAla: 8.808 ± 0.097	0.34GluCys: 0.34 ± 0.017	2.995GluAsp: 2.995 ± 0.052	2.916GluGlu: 2.916 ± 0.059	1.695GluPhe: 1.695 ± 0.034	4.889GluGly: 4.889 ± 0.067	1.025GluHis: 1.025 ± 0.03	3.222GluIle: 3.222 ± 0.045	1.564GluLys: 1.564 ± 0.039	4.896GluLeu: 4.896 ± 0.057	1.665GluMet: 1.665 ± 0.034	1.265GluAsn: 1.265 ± 0.032	2.646GluPro: 2.646 ± 0.053	1.664GluGln: 1.664 ± 0.041	4.335GluArg: 4.335 ± 0.064	1.943GluSer: 1.943 ± 0.037	3.436GluThr: 3.436 ± 0.054	4.308GluVal: 4.308 ± 0.054	0.633GluTrp: 0.633 ± 0.022	0.915GluTyr: 0.915 ± 0.029	0.0GluXaa: 0.0 ± 0.0
Phe	4.716PheAla: 4.716 ± 0.053	0.411PheCys: 0.411 ± 0.015	2.521PheAsp: 2.521 ± 0.041	1.915PheGlu: 1.915 ± 0.038	1.28PhePhe: 1.28 ± 0.037	3.688PheGly: 3.688 ± 0.052	0.744PheHis: 0.744 ± 0.023	1.441PheIle: 1.441 ± 0.036	0.725PheLys: 0.725 ± 0.022	3.404PheLeu: 3.404 ± 0.061	0.777PheMet: 0.777 ± 0.026	0.871PheAsn: 0.871 ± 0.025	1.529PhePro: 1.529 ± 0.03	0.896PheGln: 0.896 ± 0.026	2.363PheArg: 2.363 ± 0.044	1.843PheSer: 1.843 ± 0.037	1.984PheThr: 1.984 ± 0.035	2.617PheVal: 2.617 ± 0.044	0.557PheTrp: 0.557 ± 0.019	0.822PheTyr: 0.822 ± 0.025	0.0PheXaa: 0.0 ± 0.0
Gly	11.536GlyAla: 11.536 ± 0.115	0.915GlyCys: 0.915 ± 0.028	4.318GlyAsp: 4.318 ± 0.071	4.591GlyGlu: 4.591 ± 0.067	3.789GlyPhe: 3.789 ± 0.055	8.296GlyGly: 8.296 ± 0.269	2.038GlyHis: 2.038 ± 0.037	4.563GlyIle: 4.563 ± 0.061	2.847GlyLys: 2.847 ± 0.053	10.107GlyLeu: 10.107 ± 0.095	2.768GlyMet: 2.768 ± 0.049	2.029GlyAsn: 2.029 ± 0.058	4.239GlyPro: 4.239 ± 0.053	3.222GlyGln: 3.222 ± 0.05	6.83GlyArg: 6.83 ± 0.076	4.501GlySer: 4.501 ± 0.076	4.808GlyThr: 4.808 ± 0.068	6.246GlyVal: 6.246 ± 0.075	1.698GlyTrp: 1.698 ± 0.038	2.267GlyTyr: 2.267 ± 0.046	0.0GlyXaa: 0.0 ± 0.0
His	2.512HisAla: 2.512 ± 0.041	0.237HisCys: 0.237 ± 0.012	1.259HisAsp: 1.259 ± 0.037	0.99HisGlu: 0.99 ± 0.024	0.738HisPhe: 0.738 ± 0.024	1.912HisGly: 1.912 ± 0.037	0.542HisHis: 0.542 ± 0.022	0.871HisIle: 0.871 ± 0.026	0.408HisLys: 0.408 ± 0.018	2.246HisLeu: 2.246 ± 0.04	0.514HisMet: 0.514 ± 0.021	0.384HisAsn: 0.384 ± 0.016	1.518HisPro: 1.518 ± 0.035	0.538HisGln: 0.538 ± 0.02	1.472HisArg: 1.472 ± 0.033	0.932HisSer: 0.932 ± 0.024	0.778HisThr: 0.778 ± 0.022	1.52HisVal: 1.52 ± 0.036	0.372HisTrp: 0.372 ± 0.015	0.495HisTyr: 0.495 ± 0.019	0.0HisXaa: 0.0 ± 0.0
Ile	7.216IleAla: 7.216 ± 0.076	0.579IleCys: 0.579 ± 0.021	3.079IleAsp: 3.079 ± 0.052	3.112IleGlu: 3.112 ± 0.051	1.612IlePhe: 1.612 ± 0.039	4.739IleGly: 4.739 ± 0.057	0.881IleHis: 0.881 ± 0.027	1.817IleIle: 1.817 ± 0.041	1.01IleLys: 1.01 ± 0.026	4.579IleLeu: 4.579 ± 0.061	0.88IleMet: 0.88 ± 0.027	1.097IleAsn: 1.097 ± 0.028	2.239IlePro: 2.239 ± 0.036	0.962IleGln: 0.962 ± 0.024	3.335IleArg: 3.335 ± 0.046	2.565IleSer: 2.565 ± 0.045	2.586IleThr: 2.586 ± 0.043	3.653IleVal: 3.653 ± 0.056	0.674IleTrp: 0.674 ± 0.022	1.064IleTyr: 1.064 ± 0.025	0.0IleXaa: 0.0 ± 0.0
Lys	3.436LysAla: 3.436 ± 0.052	0.159LysCys: 0.159 ± 0.011	1.317LysAsp: 1.317 ± 0.033	1.109LysGlu: 1.109 ± 0.032	0.744LysPhe: 0.744 ± 0.024	2.289LysGly: 2.289 ± 0.047	0.478LysHis: 0.478 ± 0.02	1.347LysIle: 1.347 ± 0.033	0.833LysLys: 0.833 ± 0.029	2.57LysLeu: 2.57 ± 0.042	0.706LysMet: 0.706 ± 0.025	0.596LysAsn: 0.596 ± 0.021	1.601LysPro: 1.601 ± 0.043	0.685LysGln: 0.685 ± 0.023	1.878LysArg: 1.878 ± 0.041	1.375LysSer: 1.375 ± 0.031	1.585LysThr: 1.585 ± 0.035	1.969LysVal: 1.969 ± 0.039	0.288LysTrp: 0.288 ± 0.015	0.505LysTyr: 0.505 ± 0.022	0.0LysXaa: 0.0 ± 0.0
Leu	16.25LeuAla: 16.25 ± 0.138	0.962LeuCys: 0.962 ± 0.025	5.943LeuAsp: 5.943 ± 0.082	4.912LeuGlu: 4.912 ± 0.061	3.36LeuPhe: 3.36 ± 0.057	9.13LeuGly: 9.13 ± 0.077	2.062LeuHis: 2.062 ± 0.043	4.949LeuIle: 4.949 ± 0.059	2.653LeuLys: 2.653 ± 0.044	9.789LeuLeu: 9.789 ± 0.118	2.651LeuMet: 2.651 ± 0.045	2.336LeuAsn: 2.336 ± 0.043	6.447LeuPro: 6.447 ± 0.07	2.969LeuGln: 2.969 ± 0.046	7.948LeuArg: 7.948 ± 0.083	6.039LeuSer: 6.039 ± 0.07	6.043LeuThr: 6.043 ± 0.062	7.446LeuVal: 7.446 ± 0.079	1.411LeuTrp: 1.411 ± 0.031	1.87LeuTyr: 1.87 ± 0.039	0.0LeuXaa: 0.0 ± 0.0
Met	3.717MetAla: 3.717 ± 0.06	0.167MetCys: 0.167 ± 0.009	1.261MetAsp: 1.261 ± 0.031	1.242MetGlu: 1.242 ± 0.032	0.733MetPhe: 0.733 ± 0.022	2.205MetGly: 2.205 ± 0.046	0.442MetHis: 0.442 ± 0.021	1.442MetIle: 1.442 ± 0.03	0.892MetLys: 0.892 ± 0.026	2.734MetLeu: 2.734 ± 0.044	0.728MetMet: 0.728 ± 0.024	0.75MetAsn: 0.75 ± 0.024	1.665MetPro: 1.665 ± 0.033	0.963MetGln: 0.963 ± 0.027	1.916MetArg: 1.916 ± 0.032	1.531MetSer: 1.531 ± 0.033	2.168MetThr: 2.168 ± 0.04	1.929MetVal: 1.929 ± 0.039	0.205MetTrp: 0.205 ± 0.012	0.27MetTyr: 0.27 ± 0.014	0.0MetXaa: 0.0 ± 0.0
Asn	2.736AsnAla: 2.736 ± 0.043	0.208AsnCys: 0.208 ± 0.012	1.15AsnAsp: 1.15 ± 0.035	0.917AsnGlu: 0.917 ± 0.026	0.744AsnPhe: 0.744 ± 0.025	2.031AsnGly: 2.031 ± 0.043	0.443AsnHis: 0.443 ± 0.019	1.122AsnIle: 1.122 ± 0.026	0.47AsnLys: 0.47 ± 0.019	2.344AsnLeu: 2.344 ± 0.043	0.523AsnMet: 0.523 ± 0.02	0.493AsnAsn: 0.493 ± 0.02	1.692AsnPro: 1.692 ± 0.036	0.566AsnGln: 0.566 ± 0.021	1.626AsnArg: 1.626 ± 0.034	0.992AsnSer: 0.992 ± 0.027	1.098AsnThr: 1.098 ± 0.025	1.507AsnVal: 1.507 ± 0.034	0.382AsnTrp: 0.382 ± 0.016	0.525AsnTyr: 0.525 ± 0.017	0.0AsnXaa: 0.0 ± 0.0
Pro	7.808ProAla: 7.808 ± 0.094	0.438ProCys: 0.438 ± 0.021	3.66ProAsp: 3.66 ± 0.053	4.205ProGlu: 4.205 ± 0.061	1.923ProPhe: 1.923 ± 0.04	5.798ProGly: 5.798 ± 0.072	1.111ProHis: 1.111 ± 0.029	2.064ProIle: 2.064 ± 0.04	1.403ProLys: 1.403 ± 0.038	5.202ProLeu: 5.202 ± 0.063	1.449ProMet: 1.449 ± 0.031	1.087ProAsn: 1.087 ± 0.026	2.867ProPro: 2.867 ± 0.05	1.772ProGln: 1.772 ± 0.035	3.625ProArg: 3.625 ± 0.06	2.501ProSer: 2.501 ± 0.036	2.31ProThr: 2.31 ± 0.043	4.665ProVal: 4.665 ± 0.053	0.748ProTrp: 0.748 ± 0.024	1.099ProTyr: 1.099 ± 0.029	0.0ProXaa: 0.0 ± 0.0
Gln	4.18GlnAla: 4.18 ± 0.056	0.171GlnCys: 0.171 ± 0.012	1.523GlnAsp: 1.523 ± 0.033	1.369GlnGlu: 1.369 ± 0.032	0.984GlnPhe: 0.984 ± 0.027	2.768GlnGly: 2.768 ± 0.045	0.598GlnHis: 0.598 ± 0.021	1.93GlnIle: 1.93 ± 0.036	0.86GlnLys: 0.86 ± 0.026	2.657GlnLeu: 2.657 ± 0.048	1.078GlnMet: 1.078 ± 0.024	0.739GlnAsn: 0.739 ± 0.023	1.834GlnPro: 1.834 ± 0.041	1.063GlnGln: 1.063 ± 0.032	2.338GlnArg: 2.338 ± 0.041	1.592GlnSer: 1.592 ± 0.043	1.65GlnThr: 1.65 ± 0.034	2.348GlnVal: 2.348 ± 0.041	0.377GlnTrp: 0.377 ± 0.016	0.501GlnTyr: 0.501 ± 0.02	0.0GlnXaa: 0.0 ± 0.0
Arg	9.836ArgAla: 9.836 ± 0.096	0.614ArgCys: 0.614 ± 0.026	3.927ArgAsp: 3.927 ± 0.059	3.885ArgGlu: 3.885 ± 0.058	2.845ArgPhe: 2.845 ± 0.048	5.559ArgGly: 5.559 ± 0.067	1.798ArgHis: 1.798 ± 0.034	4.087ArgIle: 4.087 ± 0.051	2.11ArgLys: 2.11 ± 0.044	8.574ArgLeu: 8.574 ± 0.087	2.204ArgMet: 2.204 ± 0.038	1.654ArgAsn: 1.654 ± 0.037	4.165ArgPro: 4.165 ± 0.065	2.468ArgGln: 2.468 ± 0.044	6.221ArgArg: 6.221 ± 0.084	3.754ArgSer: 3.754 ± 0.059	3.116ArgThr: 3.116 ± 0.047	5.008ArgVal: 5.008 ± 0.066	1.123ArgTrp: 1.123 ± 0.033	1.491ArgTyr: 1.491 ± 0.034	0.0ArgXaa: 0.0 ± 0.0
Ser	6.108SerAla: 6.108 ± 0.068	0.49SerCys: 0.49 ± 0.02	2.646SerAsp: 2.646 ± 0.045	2.354SerGlu: 2.354 ± 0.045	2.054SerPhe: 2.054 ± 0.038	5.427SerGly: 5.427 ± 0.096	0.982SerHis: 0.982 ± 0.027	2.175SerIle: 2.175 ± 0.045	1.133SerLys: 1.133 ± 0.029	4.986SerLeu: 4.986 ± 0.06	1.215SerMet: 1.215 ± 0.031	1.047SerAsn: 1.047 ± 0.03	2.68SerPro: 2.68 ± 0.047	1.471SerGln: 1.471 ± 0.031	3.518SerArg: 3.518 ± 0.05	2.559SerSer: 2.559 ± 0.055	2.421SerThr: 2.421 ± 0.046	3.639SerVal: 3.639 ± 0.066	0.709SerTrp: 0.709 ± 0.021	1.211SerTyr: 1.211 ± 0.035	0.0SerXaa: 0.0 ± 0.0
Thr	6.541ThrAla: 6.541 ± 0.072	0.491ThrCys: 0.491 ± 0.021	2.858ThrAsp: 2.858 ± 0.044	2.933ThrGlu: 2.933 ± 0.048	1.766ThrPhe: 1.766 ± 0.036	5.576ThrGly: 5.576 ± 0.072	1.03ThrHis: 1.03 ± 0.027	2.451ThrIle: 2.451 ± 0.045	1.067ThrLys: 1.067 ± 0.031	5.976ThrLeu: 5.976 ± 0.077	1.211ThrMet: 1.211 ± 0.028	1.051ThrAsn: 1.051 ± 0.029	3.352ThrPro: 3.352 ± 0.051	1.357ThrGln: 1.357 ± 0.029	3.777ThrArg: 3.777 ± 0.052	2.497ThrSer: 2.497 ± 0.046	2.573ThrThr: 2.573 ± 0.047	4.174ThrVal: 4.174 ± 0.054	0.656ThrTrp: 0.656 ± 0.021	1.026ThrTyr: 1.026 ± 0.029	0.0ThrXaa: 0.0 ± 0.0
Val	9.737ValAla: 9.737 ± 0.077	0.6ValCys: 0.6 ± 0.018	3.548ValAsp: 3.548 ± 0.051	4.305ValGlu: 4.305 ± 0.057	2.78ValPhe: 2.78 ± 0.048	5.294ValGly: 5.294 ± 0.061	1.31ValHis: 1.31 ± 0.036	3.907ValIle: 3.907 ± 0.06	1.908ValLys: 1.908 ± 0.039	8.021ValLeu: 8.021 ± 0.089	2.209ValMet: 2.209 ± 0.038	1.691ValAsn: 1.691 ± 0.039	3.858ValPro: 3.858 ± 0.053	2.222ValGln: 2.222 ± 0.04	4.41ValArg: 4.41 ± 0.055	3.929ValSer: 3.929 ± 0.059	4.758ValThr: 4.758 ± 0.071	5.532ValVal: 5.532 ± 0.078	0.967ValTrp: 0.967 ± 0.026	1.34ValTyr: 1.34 ± 0.033	0.0ValXaa: 0.0 ± 0.0
Trp	1.495TrpAla: 1.495 ± 0.03	0.155TrpCys: 0.155 ± 0.01	0.698TrpAsp: 0.698 ± 0.025	0.612TrpGlu: 0.612 ± 0.021	0.547TrpPhe: 0.547 ± 0.021	1.042TrpGly: 1.042 ± 0.032	0.354TrpHis: 0.354 ± 0.017	0.682TrpIle: 0.682 ± 0.023	0.425TrpLys: 0.425 ± 0.017	1.791TrpLeu: 1.791 ± 0.038	0.411TrpMet: 0.411 ± 0.02	0.369TrpAsn: 0.369 ± 0.016	0.814TrpPro: 0.814 ± 0.023	0.693TrpGln: 0.693 ± 0.021	1.279TrpArg: 1.279 ± 0.032	0.795TrpSer: 0.795 ± 0.022	0.8TrpThr: 0.8 ± 0.024	0.874TrpVal: 0.874 ± 0.023	0.233TrpTrp: 0.233 ± 0.015	0.247TrpTyr: 0.247 ± 0.012	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.547TyrAla: 2.547 ± 0.042	0.208TyrCys: 0.208 ± 0.01	1.402TyrAsp: 1.402 ± 0.031	1.081TyrGlu: 1.081 ± 0.032	0.745TyrPhe: 0.745 ± 0.028	1.917TyrGly: 1.917 ± 0.04	0.458TyrHis: 0.458 ± 0.018	0.759TyrIle: 0.759 ± 0.023	0.488TyrLys: 0.488 ± 0.021	2.166TyrLeu: 2.166 ± 0.047	0.419TyrMet: 0.419 ± 0.017	0.506TyrAsn: 0.506 ± 0.019	1.031TyrPro: 1.031 ± 0.029	0.618TyrGln: 0.618 ± 0.023	1.54TyrArg: 1.54 ± 0.031	1.034TyrSer: 1.034 ± 0.029	1.029TyrThr: 1.029 ± 0.027	1.389TyrVal: 1.389 ± 0.033	0.303TyrTrp: 0.303 ± 0.013	0.551TyrTyr: 0.551 ± 0.024	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 5035 proteins (1461988 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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