Amino acid dipepetide frequency for Marmoricola ginsengisoli

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	19.26AlaAla: 19.26 ± 0.195	0.962AlaCys: 0.962 ± 0.026	8.334AlaAsp: 8.334 ± 0.088	8.309AlaGlu: 8.309 ± 0.12	3.703AlaPhe: 3.703 ± 0.052	12.632AlaGly: 12.632 ± 0.119	2.319AlaHis: 2.319 ± 0.04	5.179AlaIle: 5.179 ± 0.066	3.137AlaLys: 3.137 ± 0.059	13.085AlaLeu: 13.085 ± 0.118	2.7AlaMet: 2.7 ± 0.05	2.495AlaAsn: 2.495 ± 0.047	6.195AlaPro: 6.195 ± 0.094	3.48AlaGln: 3.48 ± 0.05	8.711AlaArg: 8.711 ± 0.094	6.519AlaSer: 6.519 ± 0.072	7.729AlaThr: 7.729 ± 0.101	11.22AlaVal: 11.22 ± 0.116	1.797AlaTrp: 1.797 ± 0.04	2.484AlaTyr: 2.484 ± 0.043	0.0AlaXaa: 0.0 ± 0.0
Cys	0.925CysAla: 0.925 ± 0.025	0.078CysCys: 0.078 ± 0.008	0.435CysAsp: 0.435 ± 0.019	0.373CysGlu: 0.373 ± 0.016	0.24CysPhe: 0.24 ± 0.016	0.871CysGly: 0.871 ± 0.024	0.178CysHis: 0.178 ± 0.013	0.217CysIle: 0.217 ± 0.014	0.138CysLys: 0.138 ± 0.009	0.664CysLeu: 0.664 ± 0.021	0.122CysMet: 0.122 ± 0.011	0.16CysAsn: 0.16 ± 0.011	0.446CysPro: 0.446 ± 0.02	0.165CysGln: 0.165 ± 0.012	0.497CysArg: 0.497 ± 0.02	0.482CysSer: 0.482 ± 0.019	0.497CysThr: 0.497 ± 0.021	0.61CysVal: 0.61 ± 0.021	0.115CysTrp: 0.115 ± 0.009	0.143CysTyr: 0.143 ± 0.011	0.0CysXaa: 0.0 ± 0.0
Asp	7.84AspAla: 7.84 ± 0.085	0.412AspCys: 0.412 ± 0.017	4.001AspAsp: 4.001 ± 0.068	4.131AspGlu: 4.131 ± 0.064	1.74AspPhe: 1.74 ± 0.04	6.25AspGly: 6.25 ± 0.078	1.283AspHis: 1.283 ± 0.032	2.054AspIle: 2.054 ± 0.038	1.293AspLys: 1.293 ± 0.031	7.363AspLeu: 7.363 ± 0.077	0.81AspMet: 0.81 ± 0.024	1.057AspAsn: 1.057 ± 0.033	4.464AspPro: 4.464 ± 0.059	1.936AspGln: 1.936 ± 0.04	4.588AspArg: 4.588 ± 0.068	2.53AspSer: 2.53 ± 0.045	2.676AspThr: 2.676 ± 0.054	5.636AspVal: 5.636 ± 0.08	0.924AspTrp: 0.924 ± 0.024	1.169AspTyr: 1.169 ± 0.032	0.0AspXaa: 0.0 ± 0.0
Glu	6.8GluAla: 6.8 ± 0.11	0.311GluCys: 0.311 ± 0.016	2.948GluAsp: 2.948 ± 0.055	2.963GluGlu: 2.963 ± 0.053	1.648GluPhe: 1.648 ± 0.038	3.823GluGly: 3.823 ± 0.058	1.557GluHis: 1.557 ± 0.036	2.83GluIle: 2.83 ± 0.048	1.573GluLys: 1.573 ± 0.044	6.389GluLeu: 6.389 ± 0.077	1.027GluMet: 1.027 ± 0.028	1.149GluAsn: 1.149 ± 0.031	3.007GluPro: 3.007 ± 0.062	2.165GluGln: 2.165 ± 0.042	4.59GluArg: 4.59 ± 0.072	2.825GluSer: 2.825 ± 0.047	2.997GluThr: 2.997 ± 0.048	5.227GluVal: 5.227 ± 0.075	0.713GluTrp: 0.713 ± 0.025	1.131GluTyr: 1.131 ± 0.028	0.0GluXaa: 0.0 ± 0.0
Phe	3.924PheAla: 3.924 ± 0.053	0.286PheCys: 0.286 ± 0.015	2.17PheAsp: 2.17 ± 0.048	1.649PheGlu: 1.649 ± 0.04	0.913PhePhe: 0.913 ± 0.027	3.27PheGly: 3.27 ± 0.05	0.585PheHis: 0.585 ± 0.02	0.854PheIle: 0.854 ± 0.027	0.702PheLys: 0.702 ± 0.024	2.701PheLeu: 2.701 ± 0.047	0.416PheMet: 0.416 ± 0.017	0.682PheAsn: 0.682 ± 0.028	1.374PhePro: 1.374 ± 0.034	0.706PheGln: 0.706 ± 0.024	1.778PheArg: 1.778 ± 0.038	1.714PheSer: 1.714 ± 0.033	2.139PheThr: 2.139 ± 0.043	2.623PheVal: 2.623 ± 0.049	0.417PheTrp: 0.417 ± 0.019	0.646PheTyr: 0.646 ± 0.022	0.0PheXaa: 0.0 ± 0.0
Gly	10.522GlyAla: 10.522 ± 0.098	0.809GlyCys: 0.809 ± 0.027	5.298GlyAsp: 5.298 ± 0.064	4.685GlyGlu: 4.685 ± 0.064	3.174GlyPhe: 3.174 ± 0.047	8.149GlyGly: 8.149 ± 0.111	1.844GlyHis: 1.844 ± 0.037	4.276GlyIle: 4.276 ± 0.06	2.722GlyLys: 2.722 ± 0.047	9.313GlyLeu: 9.313 ± 0.102	2.013GlyMet: 2.013 ± 0.042	2.009GlyAsn: 2.009 ± 0.046	4.439GlyPro: 4.439 ± 0.06	2.607GlyGln: 2.607 ± 0.045	6.384GlyArg: 6.384 ± 0.078	6.01GlySer: 6.01 ± 0.073	6.414GlyThr: 6.414 ± 0.104	7.86GlyVal: 7.86 ± 0.083	1.6GlyTrp: 1.6 ± 0.041	2.3GlyTyr: 2.3 ± 0.037	0.0GlyXaa: 0.0 ± 0.0
His	2.288HisAla: 2.288 ± 0.046	0.177HisCys: 0.177 ± 0.013	1.291HisAsp: 1.291 ± 0.035	1.138HisGlu: 1.138 ± 0.027	0.606HisPhe: 0.606 ± 0.018	1.968HisGly: 1.968 ± 0.041	0.596HisHis: 0.596 ± 0.021	0.563HisIle: 0.563 ± 0.023	0.329HisLys: 0.329 ± 0.016	2.278HisLeu: 2.278 ± 0.049	0.292HisMet: 0.292 ± 0.015	0.339HisAsn: 0.339 ± 0.016	1.443HisPro: 1.443 ± 0.032	0.668HisGln: 0.668 ± 0.022	1.571HisArg: 1.571 ± 0.037	0.767HisSer: 0.767 ± 0.029	0.952HisThr: 0.952 ± 0.027	1.638HisVal: 1.638 ± 0.037	0.311HisTrp: 0.311 ± 0.017	0.405HisTyr: 0.405 ± 0.017	0.0HisXaa: 0.0 ± 0.0
Ile	6.036IleAla: 6.036 ± 0.074	0.356IleCys: 0.356 ± 0.016	2.938IleAsp: 2.938 ± 0.053	2.56IleGlu: 2.56 ± 0.046	1.027IlePhe: 1.027 ± 0.031	4.414IleGly: 4.414 ± 0.064	0.662IleHis: 0.662 ± 0.023	1.199IleIle: 1.199 ± 0.035	1.042IleLys: 1.042 ± 0.032	3.09IleLeu: 3.09 ± 0.056	0.514IleMet: 0.514 ± 0.021	1.044IleAsn: 1.044 ± 0.03	2.16IlePro: 2.16 ± 0.046	0.933IleGln: 0.933 ± 0.026	2.541IleArg: 2.541 ± 0.043	2.389IleSer: 2.389 ± 0.043	2.806IleThr: 2.806 ± 0.051	3.594IleVal: 3.594 ± 0.06	0.449IleTrp: 0.449 ± 0.019	0.692IleTyr: 0.692 ± 0.025	0.0IleXaa: 0.0 ± 0.0
Lys	3.351LysAla: 3.351 ± 0.061	0.131LysCys: 0.131 ± 0.01	1.396LysAsp: 1.396 ± 0.035	1.158LysGlu: 1.158 ± 0.031	0.643LysPhe: 0.643 ± 0.023	1.893LysGly: 1.893 ± 0.047	0.509LysHis: 0.509 ± 0.018	1.113LysIle: 1.113 ± 0.033	0.997LysLys: 0.997 ± 0.037	2.212LysLeu: 2.212 ± 0.044	0.468LysMet: 0.468 ± 0.021	0.691LysAsn: 0.691 ± 0.028	1.486LysPro: 1.486 ± 0.033	0.771LysGln: 0.771 ± 0.022	1.588LysArg: 1.588 ± 0.036	1.389LysSer: 1.389 ± 0.032	1.474LysThr: 1.474 ± 0.035	2.606LysVal: 2.606 ± 0.049	0.254LysTrp: 0.254 ± 0.014	0.561LysTyr: 0.561 ± 0.02	0.0LysXaa: 0.0 ± 0.0
Leu	14.543LeuAla: 14.543 ± 0.125	0.689LeuCys: 0.689 ± 0.023	7.031LeuAsp: 7.031 ± 0.081	5.091LeuGlu: 5.091 ± 0.073	2.445LeuPhe: 2.445 ± 0.047	9.663LeuGly: 9.663 ± 0.096	1.855LeuHis: 1.855 ± 0.034	3.921LeuIle: 3.921 ± 0.056	2.181LeuLys: 2.181 ± 0.046	10.033LeuLeu: 10.033 ± 0.116	1.613LeuMet: 1.613 ± 0.035	2.068LeuAsn: 2.068 ± 0.041	5.624LeuPro: 5.624 ± 0.069	2.325LeuGln: 2.325 ± 0.041	7.354LeuArg: 7.354 ± 0.085	5.391LeuSer: 5.391 ± 0.061	6.573LeuThr: 6.573 ± 0.08	9.786LeuVal: 9.786 ± 0.101	1.159LeuTrp: 1.159 ± 0.036	1.537LeuTyr: 1.537 ± 0.037	0.0LeuXaa: 0.0 ± 0.0
Met	2.218MetAla: 2.218 ± 0.045	0.14MetCys: 0.14 ± 0.011	0.83MetAsp: 0.83 ± 0.025	0.738MetGlu: 0.738 ± 0.024	0.552MetPhe: 0.552 ± 0.022	1.31MetGly: 1.31 ± 0.034	0.355MetHis: 0.355 ± 0.019	0.831MetIle: 0.831 ± 0.023	0.578MetLys: 0.578 ± 0.023	1.862MetLeu: 1.862 ± 0.036	0.403MetMet: 0.403 ± 0.02	0.493MetAsn: 0.493 ± 0.022	1.124MetPro: 1.124 ± 0.031	0.487MetGln: 0.487 ± 0.017	1.394MetArg: 1.394 ± 0.037	1.528MetSer: 1.528 ± 0.033	1.766MetThr: 1.766 ± 0.033	1.525MetVal: 1.525 ± 0.037	0.183MetTrp: 0.183 ± 0.011	0.304MetTyr: 0.304 ± 0.015	0.0MetXaa: 0.0 ± 0.0
Asn	2.676AsnAla: 2.676 ± 0.053	0.161AsnCys: 0.161 ± 0.011	1.291AsnAsp: 1.291 ± 0.037	1.057AsnGlu: 1.057 ± 0.03	0.61AsnPhe: 0.61 ± 0.022	2.199AsnGly: 2.199 ± 0.047	0.418AsnHis: 0.418 ± 0.016	0.788AsnIle: 0.788 ± 0.025	0.549AsnLys: 0.549 ± 0.021	2.253AsnLeu: 2.253 ± 0.043	0.343AsnMet: 0.343 ± 0.016	0.568AsnAsn: 0.568 ± 0.023	1.639AsnPro: 1.639 ± 0.035	0.662AsnGln: 0.662 ± 0.022	1.369AsnArg: 1.369 ± 0.036	1.038AsnSer: 1.038 ± 0.03	1.249AsnThr: 1.249 ± 0.04	1.809AsnVal: 1.809 ± 0.038	0.273AsnTrp: 0.273 ± 0.015	0.458AsnTyr: 0.458 ± 0.02	0.0AsnXaa: 0.0 ± 0.0
Pro	7.259ProAla: 7.259 ± 0.091	0.293ProCys: 0.293 ± 0.015	4.098ProAsp: 4.098 ± 0.056	3.905ProGlu: 3.905 ± 0.058	1.604ProPhe: 1.604 ± 0.035	5.677ProGly: 5.677 ± 0.074	0.969ProHis: 0.969 ± 0.031	2.026ProIle: 2.026 ± 0.042	1.341ProLys: 1.341 ± 0.035	4.574ProLeu: 4.574 ± 0.063	1.039ProMet: 1.039 ± 0.031	1.13ProAsn: 1.13 ± 0.029	2.573ProPro: 2.573 ± 0.056	1.323ProGln: 1.323 ± 0.032	3.214ProArg: 3.214 ± 0.053	3.145ProSer: 3.145 ± 0.051	3.591ProThr: 3.591 ± 0.063	5.056ProVal: 5.056 ± 0.068	0.842ProTrp: 0.842 ± 0.025	1.174ProTyr: 1.174 ± 0.031	0.0ProXaa: 0.0 ± 0.0
Gln	3.562GlnAla: 3.562 ± 0.052	0.155GlnCys: 0.155 ± 0.01	1.291GlnAsp: 1.291 ± 0.032	1.255GlnGlu: 1.255 ± 0.032	0.819GlnPhe: 0.819 ± 0.027	2.091GlnGly: 2.091 ± 0.041	0.658GlnHis: 0.658 ± 0.024	1.293GlnIle: 1.293 ± 0.033	0.672GlnLys: 0.672 ± 0.025	3.04GlnLeu: 3.04 ± 0.039	0.529GlnMet: 0.529 ± 0.024	0.549GlnAsn: 0.549 ± 0.022	1.487GlnPro: 1.487 ± 0.033	1.131GlnGln: 1.131 ± 0.03	2.257GlnArg: 2.257 ± 0.042	1.232GlnSer: 1.232 ± 0.031	1.437GlnThr: 1.437 ± 0.033	2.963GlnVal: 2.963 ± 0.048	0.398GlnTrp: 0.398 ± 0.019	0.571GlnTyr: 0.571 ± 0.022	0.0GlnXaa: 0.0 ± 0.0
Arg	8.184ArgAla: 8.184 ± 0.094	0.471ArgCys: 0.471 ± 0.021	4.051ArgAsp: 4.051 ± 0.056	3.948ArgGlu: 3.948 ± 0.055	2.264ArgPhe: 2.264 ± 0.04	5.172ArgGly: 5.172 ± 0.07	1.556ArgHis: 1.556 ± 0.04	3.523ArgIle: 3.523 ± 0.051	1.722ArgLys: 1.722 ± 0.037	7.351ArgLeu: 7.351 ± 0.097	1.749ArgMet: 1.749 ± 0.039	1.486ArgAsn: 1.486 ± 0.037	3.688ArgPro: 3.688 ± 0.06	1.966ArgGln: 1.966 ± 0.038	6.252ArgArg: 6.252 ± 0.089	4.078ArgSer: 4.078 ± 0.06	4.774ArgThr: 4.774 ± 0.066	5.715ArgVal: 5.715 ± 0.067	1.23ArgTrp: 1.23 ± 0.033	1.607ArgTyr: 1.607 ± 0.032	0.0ArgXaa: 0.0 ± 0.0
Ser	6.823SerAla: 6.823 ± 0.088	0.416SerCys: 0.416 ± 0.02	3.028SerAsp: 3.028 ± 0.048	2.596SerGlu: 2.596 ± 0.038	1.794SerPhe: 1.794 ± 0.033	5.986SerGly: 5.986 ± 0.078	0.885SerHis: 0.885 ± 0.024	2.25SerIle: 2.25 ± 0.044	1.344SerLys: 1.344 ± 0.033	5.17SerLeu: 5.17 ± 0.066	1.394SerMet: 1.394 ± 0.033	1.204SerAsn: 1.204 ± 0.032	2.937SerPro: 2.937 ± 0.05	1.347SerGln: 1.347 ± 0.035	3.737SerArg: 3.737 ± 0.058	3.405SerSer: 3.405 ± 0.067	3.722SerThr: 3.722 ± 0.065	4.592SerVal: 4.592 ± 0.061	0.99SerTrp: 0.99 ± 0.03	1.472SerTyr: 1.472 ± 0.037	0.0SerXaa: 0.0 ± 0.0
Thr	7.779ThrAla: 7.779 ± 0.108	0.534ThrCys: 0.534 ± 0.021	3.68ThrAsp: 3.68 ± 0.053	3.201ThrGlu: 3.201 ± 0.053	2.087ThrPhe: 2.087 ± 0.041	6.492ThrGly: 6.492 ± 0.093	1.03ThrHis: 1.03 ± 0.025	2.584ThrIle: 2.584 ± 0.05	1.533ThrLys: 1.533 ± 0.039	5.928ThrLeu: 5.928 ± 0.077	1.127ThrMet: 1.127 ± 0.026	1.387ThrAsn: 1.387 ± 0.037	3.996ThrPro: 3.996 ± 0.079	1.467ThrGln: 1.467 ± 0.038	3.889ThrArg: 3.889 ± 0.053	3.865ThrSer: 3.865 ± 0.066	4.382ThrThr: 4.382 ± 0.09	5.768ThrVal: 5.768 ± 0.092	1.073ThrTrp: 1.073 ± 0.033	1.539ThrTyr: 1.539 ± 0.035	0.0ThrXaa: 0.0 ± 0.0
Val	12.109ValAla: 12.109 ± 0.122	0.669ValCys: 0.669 ± 0.022	5.708ValAsp: 5.708 ± 0.072	5.197ValGlu: 5.197 ± 0.069	2.42ValPhe: 2.42 ± 0.049	7.505ValGly: 7.505 ± 0.082	1.743ValHis: 1.743 ± 0.044	3.788ValIle: 3.788 ± 0.055	2.005ValLys: 2.005 ± 0.042	9.685ValLeu: 9.685 ± 0.092	1.517ValMet: 1.517 ± 0.031	2.045ValAsn: 2.045 ± 0.04	5.019ValPro: 5.019 ± 0.063	2.162ValGln: 2.162 ± 0.04	6.424ValArg: 6.424 ± 0.081	4.689ValSer: 4.689 ± 0.072	6.056ValThr: 6.056 ± 0.091	9.529ValVal: 9.529 ± 0.101	0.998ValTrp: 0.998 ± 0.028	1.443ValTyr: 1.443 ± 0.035	0.0ValXaa: 0.0 ± 0.0
Trp	1.538TrpAla: 1.538 ± 0.039	0.138TrpCys: 0.138 ± 0.011	0.77TrpAsp: 0.77 ± 0.025	0.647TrpGlu: 0.647 ± 0.02	0.544TrpPhe: 0.544 ± 0.02	1.028TrpGly: 1.028 ± 0.032	0.308TrpHis: 0.308 ± 0.015	0.671TrpIle: 0.671 ± 0.025	0.391TrpLys: 0.391 ± 0.016	1.652TrpLeu: 1.652 ± 0.041	0.31TrpMet: 0.31 ± 0.015	0.404TrpAsn: 0.404 ± 0.017	0.699TrpPro: 0.699 ± 0.026	0.474TrpGln: 0.474 ± 0.022	1.09TrpArg: 1.09 ± 0.028	1.008TrpSer: 1.008 ± 0.028	0.964TrpThr: 0.964 ± 0.03	1.124TrpVal: 1.124 ± 0.028	0.317TrpTrp: 0.317 ± 0.016	0.294TrpTyr: 0.294 ± 0.015	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.614TyrAla: 2.614 ± 0.047	0.166TyrCys: 0.166 ± 0.011	1.568TyrAsp: 1.568 ± 0.037	1.076TyrGlu: 1.076 ± 0.032	0.715TyrPhe: 0.715 ± 0.024	2.035TyrGly: 2.035 ± 0.039	0.309TyrHis: 0.309 ± 0.014	0.487TyrIle: 0.487 ± 0.021	0.441TyrLys: 0.441 ± 0.019	2.236TyrLeu: 2.236 ± 0.044	0.233TyrMet: 0.233 ± 0.013	0.451TyrAsn: 0.451 ± 0.017	1.035TyrPro: 1.035 ± 0.028	0.614TyrGln: 0.614 ± 0.021	1.561TyrArg: 1.561 ± 0.031	1.09TyrSer: 1.09 ± 0.029	1.141TyrThr: 1.141 ± 0.036	1.832TyrVal: 1.832 ± 0.035	0.327TyrTrp: 0.327 ± 0.017	0.463TyrTyr: 0.463 ± 0.019	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4237 proteins (1359760 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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