Amino acid dipepetide frequency for Rhynchosporium commune

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.031AlaAla: 8.031 ± 0.051	0.982AlaCys: 0.982 ± 0.015	3.904AlaAsp: 3.904 ± 0.026	4.978AlaGlu: 4.978 ± 0.041	3.088AlaPhe: 3.088 ± 0.024	5.723AlaGly: 5.723 ± 0.038	1.61AlaHis: 1.61 ± 0.019	4.411AlaIle: 4.411 ± 0.034	4.386AlaLys: 4.386 ± 0.039	7.205AlaLeu: 7.205 ± 0.045	1.913AlaMet: 1.913 ± 0.02	2.996AlaAsn: 2.996 ± 0.026	4.603AlaPro: 4.603 ± 0.045	3.183AlaGln: 3.183 ± 0.026	4.552AlaArg: 4.552 ± 0.031	7.155AlaSer: 7.155 ± 0.039	5.095AlaThr: 5.095 ± 0.032	5.039AlaVal: 5.039 ± 0.03	1.071AlaTrp: 1.071 ± 0.014	2.098AlaTyr: 2.098 ± 0.022	0.0AlaXaa: 0.0 ± 0.0
Cys	0.855CysAla: 0.855 ± 0.014	0.235CysCys: 0.235 ± 0.007	0.615CysAsp: 0.615 ± 0.012	0.614CysGlu: 0.614 ± 0.011	0.517CysPhe: 0.517 ± 0.01	0.935CysGly: 0.935 ± 0.017	0.294CysHis: 0.294 ± 0.008	0.682CysIle: 0.682 ± 0.012	0.565CysLys: 0.565 ± 0.011	1.168CysLeu: 1.168 ± 0.016	0.275CysMet: 0.275 ± 0.006	0.43CysAsn: 0.43 ± 0.01	0.643CysPro: 0.643 ± 0.014	0.421CysGln: 0.421 ± 0.008	0.645CysArg: 0.645 ± 0.012	0.916CysSer: 0.916 ± 0.014	0.684CysThr: 0.684 ± 0.012	0.749CysVal: 0.749 ± 0.013	0.185CysTrp: 0.185 ± 0.006	0.339CysTyr: 0.339 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	4.28AspAla: 4.28 ± 0.031	0.624AspCys: 0.624 ± 0.011	3.977AspAsp: 3.977 ± 0.041	4.494AspGlu: 4.494 ± 0.039	2.282AspPhe: 2.282 ± 0.024	4.064AspGly: 4.064 ± 0.032	1.176AspHis: 1.176 ± 0.017	3.149AspIle: 3.149 ± 0.029	2.416AspLys: 2.416 ± 0.026	5.024AspLeu: 5.024 ± 0.032	1.306AspMet: 1.306 ± 0.016	1.903AspAsn: 1.903 ± 0.017	3.058AspPro: 3.058 ± 0.028	1.827AspGln: 1.827 ± 0.02	2.838AspArg: 2.838 ± 0.027	4.229AspSer: 4.229 ± 0.036	2.919AspThr: 2.919 ± 0.024	3.559AspVal: 3.559 ± 0.029	0.819AspTrp: 0.819 ± 0.012	1.52AspTyr: 1.52 ± 0.016	0.0AspXaa: 0.0 ± 0.0
Glu	5.177GluAla: 5.177 ± 0.036	0.614GluCys: 0.614 ± 0.011	4.391GluAsp: 4.391 ± 0.04	5.794GluGlu: 5.794 ± 0.053	2.024GluPhe: 2.024 ± 0.021	3.984GluGly: 3.984 ± 0.031	1.318GluHis: 1.318 ± 0.017	3.407GluIle: 3.407 ± 0.029	4.221GluLys: 4.221 ± 0.036	5.054GluLeu: 5.054 ± 0.042	1.572GluMet: 1.572 ± 0.018	2.501GluAsn: 2.501 ± 0.025	2.574GluPro: 2.574 ± 0.031	2.302GluGln: 2.302 ± 0.023	3.911GluArg: 3.911 ± 0.033	4.5GluSer: 4.5 ± 0.036	3.422GluThr: 3.422 ± 0.028	3.808GluVal: 3.808 ± 0.032	0.855GluTrp: 0.855 ± 0.013	1.68GluTyr: 1.68 ± 0.017	0.0GluXaa: 0.0 ± 0.0
Phe	3.061PheAla: 3.061 ± 0.024	0.555PheCys: 0.555 ± 0.011	2.273PheAsp: 2.273 ± 0.02	2.277PheGlu: 2.277 ± 0.019	1.57PhePhe: 1.57 ± 0.019	2.924PheGly: 2.924 ± 0.03	0.859PheHis: 0.859 ± 0.014	1.884PheIle: 1.884 ± 0.02	1.712PheLys: 1.712 ± 0.016	3.371PheLeu: 3.371 ± 0.031	0.837PheMet: 0.837 ± 0.012	1.515PheAsn: 1.515 ± 0.019	1.981PhePro: 1.981 ± 0.018	1.415PheGln: 1.415 ± 0.014	1.876PheArg: 1.876 ± 0.017	3.14PheSer: 3.14 ± 0.026	2.219PheThr: 2.219 ± 0.021	2.351PheVal: 2.351 ± 0.024	0.617PheTrp: 0.617 ± 0.011	1.09PheTyr: 1.09 ± 0.016	0.0PheXaa: 0.0 ± 0.0
Gly	5.075GlyAla: 5.075 ± 0.041	0.852GlyCys: 0.852 ± 0.016	3.599GlyAsp: 3.599 ± 0.026	3.825GlyGlu: 3.825 ± 0.034	2.9GlyPhe: 2.9 ± 0.028	6.217GlyGly: 6.217 ± 0.061	1.577GlyHis: 1.577 ± 0.018	3.729GlyIle: 3.729 ± 0.028	3.957GlyLys: 3.957 ± 0.027	5.948GlyLeu: 5.948 ± 0.035	1.746GlyMet: 1.746 ± 0.021	2.879GlyAsn: 2.879 ± 0.028	3.215GlyPro: 3.215 ± 0.03	2.453GlyGln: 2.453 ± 0.026	4.037GlyArg: 4.037 ± 0.035	5.964GlySer: 5.964 ± 0.041	4.008GlyThr: 4.008 ± 0.032	4.348GlyVal: 4.348 ± 0.034	1.122GlyTrp: 1.122 ± 0.017	2.132GlyTyr: 2.132 ± 0.023	0.0GlyXaa: 0.0 ± 0.0
His	1.639HisAla: 1.639 ± 0.017	0.296HisCys: 0.296 ± 0.007	1.226HisAsp: 1.226 ± 0.013	1.299HisGlu: 1.299 ± 0.015	0.896HisPhe: 0.896 ± 0.011	1.549HisGly: 1.549 ± 0.02	0.753HisHis: 0.753 ± 0.013	1.197HisIle: 1.197 ± 0.016	0.957HisLys: 0.957 ± 0.013	2.087HisLeu: 2.087 ± 0.02	0.482HisMet: 0.482 ± 0.009	0.877HisAsn: 0.877 ± 0.014	1.497HisPro: 1.497 ± 0.018	0.949HisGln: 0.949 ± 0.015	1.357HisArg: 1.357 ± 0.018	1.833HisSer: 1.833 ± 0.021	1.273HisThr: 1.273 ± 0.017	1.335HisVal: 1.335 ± 0.016	0.3HisTrp: 0.3 ± 0.008	0.655HisTyr: 0.655 ± 0.012	0.0HisXaa: 0.0 ± 0.0
Ile	4.349IleAla: 4.349 ± 0.032	0.759IleCys: 0.759 ± 0.011	2.983IleAsp: 2.983 ± 0.027	3.212IleGlu: 3.212 ± 0.025	2.135IlePhe: 2.135 ± 0.021	3.407IleGly: 3.407 ± 0.03	1.234IleHis: 1.234 ± 0.014	2.807IleIle: 2.807 ± 0.027	2.568IleLys: 2.568 ± 0.025	4.879IleLeu: 4.879 ± 0.033	1.128IleMet: 1.128 ± 0.016	1.979IleAsn: 1.979 ± 0.023	3.246IlePro: 3.246 ± 0.025	1.979IleGln: 1.979 ± 0.021	2.784IleArg: 2.784 ± 0.022	4.46IleSer: 4.46 ± 0.034	3.155IleThr: 3.155 ± 0.027	3.277IleVal: 3.277 ± 0.024	0.757IleTrp: 0.757 ± 0.013	1.499IleTyr: 1.499 ± 0.019	0.0IleXaa: 0.0 ± 0.0
Lys	4.618LysAla: 4.618 ± 0.033	0.543LysCys: 0.543 ± 0.011	3.134LysAsp: 3.134 ± 0.028	3.854LysGlu: 3.854 ± 0.032	1.703LysPhe: 1.703 ± 0.018	3.379LysGly: 3.379 ± 0.025	1.183LysHis: 1.183 ± 0.016	2.764LysIle: 2.764 ± 0.022	3.997LysLys: 3.997 ± 0.054	4.346LysLeu: 4.346 ± 0.029	1.216LysMet: 1.216 ± 0.015	2.037LysAsn: 2.037 ± 0.023	2.841LysPro: 2.841 ± 0.029	1.915LysGln: 1.915 ± 0.021	3.53LysArg: 3.53 ± 0.033	4.199LysSer: 4.199 ± 0.028	3.161LysThr: 3.161 ± 0.029	3.12LysVal: 3.12 ± 0.024	0.725LysTrp: 0.725 ± 0.011	1.488LysTyr: 1.488 ± 0.017	0.0LysXaa: 0.0 ± 0.0
Leu	7.413LeuAla: 7.413 ± 0.044	1.1LeuCys: 1.1 ± 0.014	4.892LeuAsp: 4.892 ± 0.033	5.442LeuGlu: 5.442 ± 0.044	3.138LeuPhe: 3.138 ± 0.026	5.797LeuGly: 5.797 ± 0.04	2.054LeuHis: 2.054 ± 0.021	4.08LeuIle: 4.08 ± 0.033	4.65LeuLys: 4.65 ± 0.033	7.968LeuLeu: 7.968 ± 0.061	1.807LeuMet: 1.807 ± 0.02	3.233LeuAsn: 3.233 ± 0.024	5.405LeuPro: 5.405 ± 0.036	3.665LeuGln: 3.665 ± 0.031	5.259LeuArg: 5.259 ± 0.043	7.263LeuSer: 7.263 ± 0.045	4.859LeuThr: 4.859 ± 0.035	5.155LeuVal: 5.155 ± 0.041	1.102LeuTrp: 1.102 ± 0.017	2.25LeuTyr: 2.25 ± 0.022	0.0LeuXaa: 0.0 ± 0.0
Met	2.185MetAla: 2.185 ± 0.02	0.253MetCys: 0.253 ± 0.008	1.309MetAsp: 1.309 ± 0.017	1.38MetGlu: 1.38 ± 0.017	0.8MetPhe: 0.8 ± 0.012	1.557MetGly: 1.557 ± 0.019	0.479MetHis: 0.479 ± 0.008	1.116MetIle: 1.116 ± 0.015	1.243MetLys: 1.243 ± 0.015	1.81MetLeu: 1.81 ± 0.017	0.61MetMet: 0.61 ± 0.011	0.899MetAsn: 0.899 ± 0.015	1.282MetPro: 1.282 ± 0.017	0.873MetGln: 0.873 ± 0.012	1.255MetArg: 1.255 ± 0.015	2.064MetSer: 2.064 ± 0.022	1.32MetThr: 1.32 ± 0.016	1.329MetVal: 1.329 ± 0.016	0.272MetTrp: 0.272 ± 0.007	0.522MetTyr: 0.522 ± 0.012	0.0MetXaa: 0.0 ± 0.0
Asn	3.148AsnAla: 3.148 ± 0.025	0.47AsnCys: 0.47 ± 0.01	2.014AsnAsp: 2.014 ± 0.017	2.139AsnGlu: 2.139 ± 0.023	1.533AsnPhe: 1.533 ± 0.016	3.293AsnGly: 3.293 ± 0.028	0.909AsnHis: 0.909 ± 0.011	2.254AsnIle: 2.254 ± 0.022	1.723AsnLys: 1.723 ± 0.02	3.409AsnLeu: 3.409 ± 0.027	0.929AsnMet: 0.929 ± 0.015	1.649AsnAsn: 1.649 ± 0.026	2.507AsnPro: 2.507 ± 0.025	1.407AsnGln: 1.407 ± 0.018	1.966AsnArg: 1.966 ± 0.018	3.211AsnSer: 3.211 ± 0.031	2.448AsnThr: 2.448 ± 0.025	2.374AsnVal: 2.374 ± 0.023	0.563AsnTrp: 0.563 ± 0.01	1.117AsnTyr: 1.117 ± 0.013	0.0AsnXaa: 0.0 ± 0.0
Pro	4.944ProAla: 4.944 ± 0.043	0.479ProCys: 0.479 ± 0.011	2.845ProAsp: 2.845 ± 0.026	3.623ProGlu: 3.623 ± 0.029	2.019ProPhe: 2.019 ± 0.02	3.771ProGly: 3.771 ± 0.032	1.214ProHis: 1.214 ± 0.012	2.827ProIle: 2.827 ± 0.024	2.919ProLys: 2.919 ± 0.026	4.603ProLeu: 4.603 ± 0.032	1.105ProMet: 1.105 ± 0.016	2.277ProAsn: 2.277 ± 0.024	4.779ProPro: 4.779 ± 0.053	2.363ProGln: 2.363 ± 0.03	3.244ProArg: 3.244 ± 0.031	5.995ProSer: 5.995 ± 0.047	4.046ProThr: 4.046 ± 0.031	3.44ProVal: 3.44 ± 0.029	0.658ProTrp: 0.658 ± 0.011	1.467ProTyr: 1.467 ± 0.019	0.0ProXaa: 0.0 ± 0.0
Gln	3.271GlnAla: 3.271 ± 0.027	0.408GlnCys: 0.408 ± 0.009	2.028GlnAsp: 2.028 ± 0.02	2.33GlnGlu: 2.33 ± 0.025	1.29GlnPhe: 1.29 ± 0.017	2.316GlnGly: 2.316 ± 0.021	1.003GlnHis: 1.003 ± 0.015	2.064GlnIle: 2.064 ± 0.019	2.174GlnLys: 2.174 ± 0.02	3.135GlnLeu: 3.135 ± 0.024	0.895GlnMet: 0.895 ± 0.016	1.724GlnAsn: 1.724 ± 0.021	2.255GlnPro: 2.255 ± 0.026	2.275GlnGln: 2.275 ± 0.044	2.455GlnArg: 2.455 ± 0.022	3.211GlnSer: 3.211 ± 0.032	2.311GlnThr: 2.311 ± 0.024	2.118GlnVal: 2.118 ± 0.022	0.497GlnTrp: 0.497 ± 0.009	1.176GlnTyr: 1.176 ± 0.017	0.0GlnXaa: 0.0 ± 0.0
Arg	4.291ArgAla: 4.291 ± 0.029	0.642ArgCys: 0.642 ± 0.013	3.218ArgAsp: 3.218 ± 0.03	3.796ArgGlu: 3.796 ± 0.036	2.003ArgPhe: 2.003 ± 0.019	3.761ArgGly: 3.761 ± 0.036	1.348ArgHis: 1.348 ± 0.018	2.962ArgIle: 2.962 ± 0.025	3.676ArgLys: 3.676 ± 0.032	4.917ArgLeu: 4.917 ± 0.033	1.302ArgMet: 1.302 ± 0.017	2.373ArgAsn: 2.373 ± 0.022	3.194ArgPro: 3.194 ± 0.03	2.391ArgGln: 2.391 ± 0.022	4.568ArgArg: 4.568 ± 0.039	4.781ArgSer: 4.781 ± 0.037	3.219ArgThr: 3.219 ± 0.029	3.104ArgVal: 3.104 ± 0.027	0.814ArgTrp: 0.814 ± 0.014	1.541ArgTyr: 1.541 ± 0.016	0.0ArgXaa: 0.0 ± 0.0
Ser	6.602SerAla: 6.602 ± 0.043	0.875SerCys: 0.875 ± 0.015	4.25SerAsp: 4.25 ± 0.032	4.454SerGlu: 4.454 ± 0.036	3.171SerPhe: 3.171 ± 0.024	5.787SerGly: 5.787 ± 0.038	1.885SerHis: 1.885 ± 0.02	4.525SerIle: 4.525 ± 0.031	4.381SerLys: 4.381 ± 0.035	7.252SerLeu: 7.252 ± 0.047	1.879SerMet: 1.879 ± 0.019	3.461SerAsn: 3.461 ± 0.03	5.716SerPro: 5.716 ± 0.048	3.446SerGln: 3.446 ± 0.032	5.037SerArg: 5.037 ± 0.037	9.767SerSer: 9.767 ± 0.103	6.155SerThr: 6.155 ± 0.051	4.59SerVal: 4.59 ± 0.036	1.065SerTrp: 1.065 ± 0.016	2.183SerTyr: 2.183 ± 0.023	0.0SerXaa: 0.0 ± 0.0
Thr	5.02ThrAla: 5.02 ± 0.039	0.754ThrCys: 0.754 ± 0.014	2.763ThrAsp: 2.763 ± 0.023	3.089ThrGlu: 3.089 ± 0.026	2.397ThrPhe: 2.397 ± 0.025	4.165ThrGly: 4.165 ± 0.031	1.255ThrHis: 1.255 ± 0.016	3.486ThrIle: 3.486 ± 0.025	2.986ThrLys: 2.986 ± 0.022	5.234ThrLeu: 5.234 ± 0.038	1.211ThrMet: 1.211 ± 0.016	2.306ThrAsn: 2.306 ± 0.021	4.394ThrPro: 4.394 ± 0.037	2.133ThrGln: 2.133 ± 0.019	3.069ThrArg: 3.069 ± 0.025	6.031ThrSer: 6.031 ± 0.047	4.426ThrThr: 4.426 ± 0.047	3.557ThrVal: 3.557 ± 0.031	0.811ThrTrp: 0.811 ± 0.014	1.677ThrTyr: 1.677 ± 0.021	0.0ThrXaa: 0.0 ± 0.0
Val	4.978ValAla: 4.978 ± 0.03	0.751ValCys: 0.751 ± 0.012	3.552ValAsp: 3.552 ± 0.031	4.073ValGlu: 4.073 ± 0.03	2.36ValPhe: 2.36 ± 0.023	3.978ValGly: 3.978 ± 0.028	1.266ValHis: 1.266 ± 0.016	3.043ValIle: 3.043 ± 0.025	3.165ValLys: 3.165 ± 0.025	5.381ValLeu: 5.381 ± 0.037	1.357ValMet: 1.357 ± 0.016	2.219ValAsn: 2.219 ± 0.021	3.433ValPro: 3.433 ± 0.03	2.269ValGln: 2.269 ± 0.022	3.193ValArg: 3.193 ± 0.024	4.632ValSer: 4.632 ± 0.033	3.482ValThr: 3.482 ± 0.03	4.183ValVal: 4.183 ± 0.03	0.825ValTrp: 0.825 ± 0.014	1.655ValTyr: 1.655 ± 0.019	0.0ValXaa: 0.0 ± 0.0
Trp	1.033TrpAla: 1.033 ± 0.015	0.18TrpCys: 0.18 ± 0.005	0.854TrpAsp: 0.854 ± 0.014	0.847TrpGlu: 0.847 ± 0.012	0.52TrpPhe: 0.52 ± 0.011	0.916TrpGly: 0.916 ± 0.014	0.317TrpHis: 0.317 ± 0.008	0.77TrpIle: 0.77 ± 0.012	0.845TrpLys: 0.845 ± 0.011	1.188TrpLeu: 1.188 ± 0.015	0.374TrpMet: 0.374 ± 0.008	0.631TrpAsn: 0.631 ± 0.011	0.537TrpPro: 0.537 ± 0.01	0.527TrpGln: 0.527 ± 0.011	0.823TrpArg: 0.823 ± 0.014	1.006TrpSer: 1.006 ± 0.014	0.864TrpThr: 0.864 ± 0.014	0.831TrpVal: 0.831 ± 0.011	0.252TrpTrp: 0.252 ± 0.008	0.401TrpTyr: 0.401 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.053TyrAla: 2.053 ± 0.021	0.394TyrCys: 0.394 ± 0.008	1.636TyrAsp: 1.636 ± 0.017	1.589TyrGlu: 1.589 ± 0.017	1.182TyrPhe: 1.182 ± 0.016	2.061TyrGly: 2.061 ± 0.021	0.723TyrHis: 0.723 ± 0.012	1.439TyrIle: 1.439 ± 0.019	1.213TyrLys: 1.213 ± 0.016	2.553TyrLeu: 2.553 ± 0.027	0.614TyrMet: 0.614 ± 0.009	1.173TyrAsn: 1.173 ± 0.017	1.46TyrPro: 1.46 ± 0.016	1.141TyrGln: 1.141 ± 0.017	1.501TyrArg: 1.501 ± 0.016	2.125TyrSer: 2.125 ± 0.023	1.694TyrThr: 1.694 ± 0.019	1.53TyrVal: 1.53 ± 0.016	0.407TyrTrp: 0.407 ± 0.01	0.873TyrTyr: 0.873 ± 0.015	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.001XaaXaa: 0.001 ± 0.0

Statistics based on 12210 proteins (5554614 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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