Amino acid dipepetide frequency for Bean leaf crumple virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.774AlaAla: 3.774 ± 1.436
0.629AlaCys: 0.629 ± 0.639
1.258AlaAsp: 1.258 ± 0.666
1.887AlaGlu: 1.887 ± 0.702
1.887AlaPhe: 1.887 ± 1.159
3.145AlaGly: 3.145 ± 1.387
1.258AlaHis: 1.258 ± 0.779
1.887AlaIle: 1.887 ± 0.692
5.031AlaLys: 5.031 ± 1.011
3.774AlaLeu: 3.774 ± 1.593
0.629AlaMet: 0.629 ± 0.49
1.258AlaAsn: 1.258 ± 0.613
5.031AlaPro: 5.031 ± 2.075
3.145AlaGln: 3.145 ± 0.899
4.403AlaArg: 4.403 ± 1.757
6.918AlaSer: 6.918 ± 1.986
2.516AlaThr: 2.516 ± 1.306
1.258AlaVal: 1.258 ± 0.653
1.258AlaTrp: 1.258 ± 0.681
0.629AlaTyr: 0.629 ± 0.49
0.0AlaXaa: 0.0 ± 0.0
Cys
1.887CysAla: 1.887 ± 1.521
0.629CysCys: 0.629 ± 0.507
1.258CysAsp: 1.258 ± 0.571
1.258CysGlu: 1.258 ± 0.681
0.629CysPhe: 0.629 ± 0.607
0.629CysGly: 0.629 ± 0.507
0.0CysHis: 0.0 ± 0.0
1.887CysIle: 1.887 ± 1.011
1.258CysLys: 1.258 ± 0.681
1.887CysLeu: 1.887 ± 0.771
0.629CysMet: 0.629 ± 0.5
1.887CysAsn: 1.887 ± 0.655
0.629CysPro: 0.629 ± 0.607
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
1.887CysSer: 1.887 ± 1.015
0.629CysThr: 0.629 ± 0.639
1.258CysVal: 1.258 ± 0.683
1.258CysTrp: 1.258 ± 0.981
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
1.887AspAla: 1.887 ± 0.704
0.629AspCys: 0.629 ± 0.49
2.516AspAsp: 2.516 ± 1.024
3.145AspGlu: 3.145 ± 0.464
3.145AspPhe: 3.145 ± 0.982
1.887AspGly: 1.887 ± 0.771
1.258AspHis: 1.258 ± 0.681
4.403AspIle: 4.403 ± 1.084
3.145AspLys: 3.145 ± 0.995
5.031AspLeu: 5.031 ± 1.201
0.629AspMet: 0.629 ± 0.49
2.516AspAsn: 2.516 ± 1.086
2.516AspPro: 2.516 ± 1.029
0.629AspGln: 0.629 ± 0.49
5.031AspArg: 5.031 ± 1.399
3.145AspSer: 3.145 ± 0.914
1.887AspThr: 1.887 ± 0.951
4.403AspVal: 4.403 ± 1.498
0.629AspTrp: 0.629 ± 0.497
1.887AspTyr: 1.887 ± 1.003
0.0AspXaa: 0.0 ± 0.0
Glu
2.516GluAla: 2.516 ± 1.434
0.629GluCys: 0.629 ± 0.5
1.258GluAsp: 1.258 ± 0.746
1.258GluGlu: 1.258 ± 0.994
1.258GluPhe: 1.258 ± 0.794
4.403GluGly: 4.403 ± 1.355
1.258GluHis: 1.258 ± 0.666
3.145GluIle: 3.145 ± 1.667
0.629GluLys: 0.629 ± 0.49
3.145GluLeu: 3.145 ± 0.709
0.629GluMet: 0.629 ± 0.497
3.774GluAsn: 3.774 ± 2.025
2.516GluPro: 2.516 ± 0.691
1.258GluGln: 1.258 ± 1.277
2.516GluArg: 2.516 ± 1.287
6.918GluSer: 6.918 ± 2.221
0.629GluThr: 0.629 ± 0.49
1.887GluVal: 1.887 ± 0.867
0.0GluTrp: 0.0 ± 0.0
1.887GluTyr: 1.887 ± 0.951
0.0GluXaa: 0.0 ± 0.0
Phe
1.258PheAla: 1.258 ± 0.779
0.629PheCys: 0.629 ± 0.639
2.516PheAsp: 2.516 ± 0.913
0.0PheGlu: 0.0 ± 0.0
1.258PhePhe: 1.258 ± 0.571
3.145PheGly: 3.145 ± 0.818
1.887PheHis: 1.887 ± 0.951
1.887PheIle: 1.887 ± 0.988
5.031PheLys: 5.031 ± 1.731
3.774PheLeu: 3.774 ± 1.356
0.0PheMet: 0.0 ± 0.0
3.774PheAsn: 3.774 ± 0.596
1.887PhePro: 1.887 ± 0.951
3.145PheGln: 3.145 ± 1.015
3.145PheArg: 3.145 ± 0.912
3.774PheSer: 3.774 ± 1.523
1.887PheThr: 1.887 ± 0.873
1.887PheVal: 1.887 ± 0.993
1.887PheTrp: 1.887 ± 1.349
2.516PheTyr: 2.516 ± 1.434
0.0PheXaa: 0.0 ± 0.0
Gly
3.145GlyAla: 3.145 ± 1.453
1.887GlyCys: 1.887 ± 0.77
2.516GlyAsp: 2.516 ± 1.4
3.145GlyGlu: 3.145 ± 0.932
3.145GlyPhe: 3.145 ± 1.03
2.516GlyGly: 2.516 ± 1.057
1.258GlyHis: 1.258 ± 0.613
1.887GlyIle: 1.887 ± 0.766
6.289GlyLys: 6.289 ± 2.004
3.145GlyLeu: 3.145 ± 1.025
0.629GlyMet: 0.629 ± 0.482
1.887GlyAsn: 1.887 ± 0.777
3.145GlyPro: 3.145 ± 0.464
1.887GlyGln: 1.887 ± 1.223
1.258GlyArg: 1.258 ± 0.735
5.031GlySer: 5.031 ± 1.531
3.145GlyThr: 3.145 ± 1.238
3.145GlyVal: 3.145 ± 1.262
0.629GlyTrp: 0.629 ± 0.49
1.258GlyTyr: 1.258 ± 0.681
0.0GlyXaa: 0.0 ± 0.0
His
0.629HisAla: 0.629 ± 0.639
1.887HisCys: 1.887 ± 0.632
2.516HisAsp: 2.516 ± 1.013
1.887HisGlu: 1.887 ± 0.876
0.629HisPhe: 0.629 ± 0.5
0.629HisGly: 0.629 ± 0.49
2.516HisHis: 2.516 ± 0.994
1.887HisIle: 1.887 ± 0.837
2.516HisLys: 2.516 ± 0.912
3.145HisLeu: 3.145 ± 1.586
0.0HisMet: 0.0 ± 0.0
1.887HisAsn: 1.887 ± 0.708
2.516HisPro: 2.516 ± 0.954
2.516HisGln: 2.516 ± 0.92
1.887HisArg: 1.887 ± 1.17
3.145HisSer: 3.145 ± 1.241
1.258HisThr: 1.258 ± 1.277
3.145HisVal: 3.145 ± 0.963
0.629HisTrp: 0.629 ± 0.497
1.887HisTyr: 1.887 ± 0.71
0.0HisXaa: 0.0 ± 0.0
Ile
0.629IleAla: 0.629 ± 0.507
0.629IleCys: 0.629 ± 0.607
3.774IleAsp: 3.774 ± 1.329
4.403IleGlu: 4.403 ± 1.603
3.774IlePhe: 3.774 ± 1.999
2.516IleGly: 2.516 ± 1.183
2.516IleHis: 2.516 ± 1.051
2.516IleIle: 2.516 ± 1.246
6.289IleLys: 6.289 ± 1.603
3.145IleLeu: 3.145 ± 1.122
0.0IleMet: 0.0 ± 0.0
3.145IleAsn: 3.145 ± 0.995
5.031IlePro: 5.031 ± 1.78
3.145IleGln: 3.145 ± 1.294
4.403IleArg: 4.403 ± 0.691
5.031IleSer: 5.031 ± 1.382
4.403IleThr: 4.403 ± 1.372
5.031IleVal: 5.031 ± 1.561
1.258IleTrp: 1.258 ± 0.849
2.516IleTyr: 2.516 ± 1.306
0.0IleXaa: 0.0 ± 0.0
Lys
3.774LysAla: 3.774 ± 0.846
1.258LysCys: 1.258 ± 1.215
6.289LysAsp: 6.289 ± 2.202
3.774LysGlu: 3.774 ± 1.817
3.145LysPhe: 3.145 ± 1.145
2.516LysGly: 2.516 ± 0.519
1.258LysHis: 1.258 ± 0.571
4.403LysIle: 4.403 ± 1.317
0.629LysLys: 0.629 ± 0.607
5.031LysLeu: 5.031 ± 1.037
2.516LysMet: 2.516 ± 1.176
3.774LysAsn: 3.774 ± 1.498
3.145LysPro: 3.145 ± 1.334
1.258LysGln: 1.258 ± 0.681
6.918LysArg: 6.918 ± 2.07
4.403LysSer: 4.403 ± 1.082
3.774LysThr: 3.774 ± 1.244
5.66LysVal: 5.66 ± 2.841
0.629LysTrp: 0.629 ± 0.5
1.258LysTyr: 1.258 ± 0.681
0.0LysXaa: 0.0 ± 0.0
Leu
0.0LeuAla: 0.0 ± 0.0
1.258LeuCys: 1.258 ± 0.613
5.66LeuAsp: 5.66 ± 1.217
0.629LeuGlu: 0.629 ± 0.608
2.516LeuPhe: 2.516 ± 0.851
3.774LeuGly: 3.774 ± 1.309
3.774LeuHis: 3.774 ± 0.969
1.887LeuIle: 1.887 ± 0.993
8.176LeuLys: 8.176 ± 1.501
3.145LeuLeu: 3.145 ± 1.312
0.629LeuMet: 0.629 ± 0.471
5.031LeuAsn: 5.031 ± 1.626
1.258LeuPro: 1.258 ± 0.807
3.774LeuGln: 3.774 ± 1.713
1.887LeuArg: 1.887 ± 0.85
8.176LeuSer: 8.176 ± 2.419
4.403LeuThr: 4.403 ± 1.285
5.66LeuVal: 5.66 ± 1.782
0.0LeuTrp: 0.0 ± 0.0
4.403LeuTyr: 4.403 ± 1.751
0.0LeuXaa: 0.0 ± 0.0
Met
1.258MetAla: 1.258 ± 1.277
0.629MetCys: 0.629 ± 0.639
1.887MetAsp: 1.887 ± 0.85
1.887MetGlu: 1.887 ± 0.752
1.258MetPhe: 1.258 ± 1.277
0.629MetGly: 0.629 ± 0.49
1.258MetHis: 1.258 ± 0.794
0.0MetIle: 0.0 ± 0.0
1.258MetLys: 1.258 ± 0.742
1.258MetLeu: 1.258 ± 0.735
0.0MetMet: 0.0 ± 0.0
0.629MetAsn: 0.629 ± 0.608
1.258MetPro: 1.258 ± 0.735
1.887MetGln: 1.887 ± 0.873
0.629MetArg: 0.629 ± 0.49
1.887MetSer: 1.887 ± 1.076
1.258MetThr: 1.258 ± 0.681
2.516MetVal: 2.516 ± 1.003
0.629MetTrp: 0.629 ± 0.497
1.887MetTyr: 1.887 ± 1.226
0.0MetXaa: 0.0 ± 0.0
Asn
6.918AsnAla: 6.918 ± 2.462
3.145AsnCys: 3.145 ± 0.951
1.258AsnAsp: 1.258 ± 0.681
3.145AsnGlu: 3.145 ± 1.178
0.629AsnPhe: 0.629 ± 0.608
2.516AsnGly: 2.516 ± 0.708
3.774AsnHis: 3.774 ± 2.748
7.547AsnIle: 7.547 ± 1.855
1.887AsnLys: 1.887 ± 0.639
1.887AsnLeu: 1.887 ± 1.269
2.516AsnMet: 2.516 ± 1.73
1.258AsnAsn: 1.258 ± 0.849
3.774AsnPro: 3.774 ± 1.186
0.629AsnGln: 0.629 ± 0.607
3.774AsnArg: 3.774 ± 1.461
3.774AsnSer: 3.774 ± 0.897
1.258AsnThr: 1.258 ± 0.571
3.145AsnVal: 3.145 ± 0.807
0.629AsnTrp: 0.629 ± 0.497
4.403AsnTyr: 4.403 ± 1.134
0.0AsnXaa: 0.0 ± 0.0
Pro
0.0ProAla: 0.0 ± 0.0
0.629ProCys: 0.629 ± 0.639
1.887ProAsp: 1.887 ± 0.777
1.887ProGlu: 1.887 ± 0.873
1.258ProPhe: 1.258 ± 0.571
3.145ProGly: 3.145 ± 1.4
1.887ProHis: 1.887 ± 1.003
5.031ProIle: 5.031 ± 2.304
3.774ProLys: 3.774 ± 1.001
3.774ProLeu: 3.774 ± 1.251
1.887ProMet: 1.887 ± 1.3
5.031ProAsn: 5.031 ± 1.356
1.887ProPro: 1.887 ± 0.632
1.887ProGln: 1.887 ± 1.075
4.403ProArg: 4.403 ± 1.156
7.547ProSer: 7.547 ± 1.633
2.516ProThr: 2.516 ± 1.231
3.145ProVal: 3.145 ± 1.301
1.887ProTrp: 1.887 ± 0.593
1.258ProTyr: 1.258 ± 0.683
0.0ProXaa: 0.0 ± 0.0
Gln
4.403GlnAla: 4.403 ± 0.521
0.629GlnCys: 0.629 ± 0.497
1.258GlnAsp: 1.258 ± 0.666
1.887GlnGlu: 1.887 ± 0.933
1.887GlnPhe: 1.887 ± 1.089
0.0GlnGly: 0.0 ± 0.0
1.887GlnHis: 1.887 ± 0.692
1.258GlnIle: 1.258 ± 0.735
1.258GlnLys: 1.258 ± 0.994
3.774GlnLeu: 3.774 ± 1.902
0.629GlnMet: 0.629 ± 0.497
1.258GlnAsn: 1.258 ± 0.666
2.516GlnPro: 2.516 ± 1.176
0.629GlnGln: 0.629 ± 0.5
3.774GlnArg: 3.774 ± 1.412
5.031GlnSer: 5.031 ± 1.105
0.629GlnThr: 0.629 ± 0.607
3.145GlnVal: 3.145 ± 1.65
0.0GlnTrp: 0.0 ± 0.0
1.258GlnTyr: 1.258 ± 0.681
0.0GlnXaa: 0.0 ± 0.0
Arg
3.145ArgAla: 3.145 ± 1.181
0.629ArgCys: 0.629 ± 0.5
3.774ArgAsp: 3.774 ± 1.776
1.887ArgGlu: 1.887 ± 0.873
6.918ArgPhe: 6.918 ± 1.659
4.403ArgGly: 4.403 ± 1.517
2.516ArgHis: 2.516 ± 1.42
5.66ArgIle: 5.66 ± 1.832
2.516ArgLys: 2.516 ± 0.912
3.774ArgLeu: 3.774 ± 1.245
3.145ArgMet: 3.145 ± 0.889
2.516ArgAsn: 2.516 ± 1.217
3.774ArgPro: 3.774 ± 0.915
1.887ArgGln: 1.887 ± 0.831
8.176ArgArg: 8.176 ± 2.505
6.289ArgSer: 6.289 ± 2.109
5.66ArgThr: 5.66 ± 1.491
3.774ArgVal: 3.774 ± 1.036
0.0ArgTrp: 0.0 ± 0.0
2.516ArgTyr: 2.516 ± 1.098
0.0ArgXaa: 0.0 ± 0.0
Ser
4.403SerAla: 4.403 ± 1.603
1.258SerCys: 1.258 ± 0.619
3.145SerAsp: 3.145 ± 0.794
1.887SerGlu: 1.887 ± 1.253
3.145SerPhe: 3.145 ± 1.166
6.289SerGly: 6.289 ± 1.306
3.145SerHis: 3.145 ± 1.01
6.918SerIle: 6.918 ± 1.376
5.031SerLys: 5.031 ± 0.961
5.031SerLeu: 5.031 ± 1.821
2.516SerMet: 2.516 ± 1.413
6.918SerAsn: 6.918 ± 1.356
3.774SerPro: 3.774 ± 2.092
1.887SerGln: 1.887 ± 1.499
8.805SerArg: 8.805 ± 2.252
8.176SerSer: 8.176 ± 2.556
10.063SerThr: 10.063 ± 2.366
5.031SerVal: 5.031 ± 1.704
1.887SerTrp: 1.887 ± 0.951
2.516SerTyr: 2.516 ± 0.973
0.0SerXaa: 0.0 ± 0.0
Thr
5.031ThrAla: 5.031 ± 1.19
0.0ThrCys: 0.0 ± 0.0
2.516ThrAsp: 2.516 ± 1.029
1.887ThrGlu: 1.887 ± 0.704
3.145ThrPhe: 3.145 ± 1.044
3.145ThrGly: 3.145 ± 0.962
3.145ThrHis: 3.145 ± 1.095
1.258ThrIle: 1.258 ± 0.635
1.258ThrLys: 1.258 ± 0.666
5.031ThrLeu: 5.031 ± 1.528
1.258ThrMet: 1.258 ± 0.571
4.403ThrAsn: 4.403 ± 1.052
4.403ThrPro: 4.403 ± 1.957
1.887ThrGln: 1.887 ± 0.843
3.145ThrArg: 3.145 ± 1.529
3.774ThrSer: 3.774 ± 1.678
1.887ThrThr: 1.887 ± 1.305
1.887ThrVal: 1.887 ± 1.011
0.0ThrTrp: 0.0 ± 0.0
3.774ThrTyr: 3.774 ± 1.219
0.0ThrXaa: 0.0 ± 0.0
Val
1.887ValAla: 1.887 ± 1.49
0.629ValCys: 0.629 ± 0.5
3.145ValAsp: 3.145 ± 1.998
3.145ValGlu: 3.145 ± 1.155
3.145ValPhe: 3.145 ± 1.141
3.774ValGly: 3.774 ± 1.047
1.258ValHis: 1.258 ± 0.999
6.289ValIle: 6.289 ± 2.021
5.66ValLys: 5.66 ± 2.138
1.887ValLeu: 1.887 ± 0.702
2.516ValMet: 2.516 ± 1.832
3.774ValAsn: 3.774 ± 1.834
3.145ValPro: 3.145 ± 0.752
3.145ValGln: 3.145 ± 0.733
5.031ValArg: 5.031 ± 1.83
3.774ValSer: 3.774 ± 1.036
1.258ValThr: 1.258 ± 1.277
3.145ValVal: 3.145 ± 1.077
0.629ValTrp: 0.629 ± 0.608
3.774ValTyr: 3.774 ± 1.725
0.0ValXaa: 0.0 ± 0.0
Trp
2.516TrpAla: 2.516 ± 1.4
0.629TrpCys: 0.629 ± 0.49
0.629TrpAsp: 0.629 ± 0.507
1.258TrpGlu: 1.258 ± 0.779
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
1.887TrpLys: 1.887 ± 0.593
0.629TrpLeu: 0.629 ± 0.639
1.258TrpMet: 1.258 ± 0.681
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.629TrpGln: 0.629 ± 0.497
0.629TrpArg: 0.629 ± 0.639
1.258TrpSer: 1.258 ± 0.613
1.887TrpThr: 1.887 ± 0.702
0.629TrpVal: 0.629 ± 0.639
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.516TyrAla: 2.516 ± 1.832
1.258TyrCys: 1.258 ± 0.613
1.258TyrAsp: 1.258 ± 0.681
1.258TyrGlu: 1.258 ± 1.277
2.516TyrPhe: 2.516 ± 0.679
1.887TyrGly: 1.887 ± 0.593
1.258TyrHis: 1.258 ± 0.653
4.403TyrIle: 4.403 ± 0.798
2.516TyrLys: 2.516 ± 0.954
3.774TyrLeu: 3.774 ± 1.804
1.258TyrMet: 1.258 ± 0.83
3.145TyrAsn: 3.145 ± 0.914
2.516TyrPro: 2.516 ± 1.063
1.887TyrGln: 1.887 ± 0.593
3.145TyrArg: 3.145 ± 1.876
1.887TyrSer: 1.887 ± 0.639
1.887TyrThr: 1.887 ± 0.94
1.258TyrVal: 1.258 ± 0.746
0.0TyrTrp: 0.0 ± 0.0
2.516TyrTyr: 2.516 ± 1.006
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (1591 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski