Amino acid dipepetide frequency for Pseudohoeflea suaedae

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	15.478AlaAla: 15.478 ± 0.168	0.906AlaCys: 0.906 ± 0.03	7.058AlaAsp: 7.058 ± 0.086	8.069AlaGlu: 8.069 ± 0.095	4.507AlaPhe: 4.507 ± 0.061	10.885AlaGly: 10.885 ± 0.116	2.135AlaHis: 2.135 ± 0.047	6.794AlaIle: 6.794 ± 0.083	3.758AlaLys: 3.758 ± 0.071	11.764AlaLeu: 11.764 ± 0.137	3.516AlaMet: 3.516 ± 0.059	3.05AlaAsn: 3.05 ± 0.059	4.925AlaPro: 4.925 ± 0.079	3.288AlaGln: 3.288 ± 0.064	8.366AlaArg: 8.366 ± 0.101	6.422AlaSer: 6.422 ± 0.08	5.565AlaThr: 5.565 ± 0.069	8.052AlaVal: 8.052 ± 0.095	1.388AlaTrp: 1.388 ± 0.039	2.616AlaTyr: 2.616 ± 0.053	0.0AlaXaa: 0.0 ± 0.0
Cys	0.864CysAla: 0.864 ± 0.028	0.091CysCys: 0.091 ± 0.009	0.538CysAsp: 0.538 ± 0.021	0.499CysGlu: 0.499 ± 0.022	0.318CysPhe: 0.318 ± 0.019	0.942CysGly: 0.942 ± 0.032	0.228CysHis: 0.228 ± 0.015	0.359CysIle: 0.359 ± 0.018	0.211CysLys: 0.211 ± 0.013	0.785CysLeu: 0.785 ± 0.027	0.17CysMet: 0.17 ± 0.014	0.218CysAsn: 0.218 ± 0.014	0.43CysPro: 0.43 ± 0.02	0.197CysGln: 0.197 ± 0.013	0.567CysArg: 0.567 ± 0.025	0.425CysSer: 0.425 ± 0.021	0.392CysThr: 0.392 ± 0.02	0.568CysVal: 0.568 ± 0.028	0.1CysTrp: 0.1 ± 0.009	0.193CysTyr: 0.193 ± 0.016	0.0CysXaa: 0.0 ± 0.0
Asp	6.803AspAla: 6.803 ± 0.086	0.519AspCys: 0.519 ± 0.025	3.578AspAsp: 3.578 ± 0.073	4.051AspGlu: 4.051 ± 0.065	2.448AspPhe: 2.448 ± 0.047	5.747AspGly: 5.747 ± 0.074	1.385AspHis: 1.385 ± 0.04	3.768AspIle: 3.768 ± 0.06	2.074AspLys: 2.074 ± 0.044	5.723AspLeu: 5.723 ± 0.074	1.683AspMet: 1.683 ± 0.043	1.558AspAsn: 1.558 ± 0.041	3.399AspPro: 3.399 ± 0.063	1.623AspGln: 1.623 ± 0.042	4.385AspArg: 4.385 ± 0.068	2.308AspSer: 2.308 ± 0.052	2.8AspThr: 2.8 ± 0.05	4.167AspVal: 4.167 ± 0.063	0.945AspTrp: 0.945 ± 0.029	1.574AspTyr: 1.574 ± 0.039	0.0AspXaa: 0.0 ± 0.0
Glu	8.014GluAla: 8.014 ± 0.102	0.384GluCys: 0.384 ± 0.017	3.471GluAsp: 3.471 ± 0.059	3.921GluGlu: 3.921 ± 0.079	2.005GluPhe: 2.005 ± 0.041	4.882GluGly: 4.882 ± 0.079	1.198GluHis: 1.198 ± 0.033	4.153GluIle: 4.153 ± 0.061	2.921GluLys: 2.921 ± 0.054	5.612GluLeu: 5.612 ± 0.079	1.898GluMet: 1.898 ± 0.039	2.15GluAsn: 2.15 ± 0.046	2.849GluPro: 2.849 ± 0.066	1.943GluGln: 1.943 ± 0.045	4.872GluArg: 4.872 ± 0.083	2.581GluSer: 2.581 ± 0.055	4.156GluThr: 4.156 ± 0.062	3.991GluVal: 3.991 ± 0.067	0.763GluTrp: 0.763 ± 0.026	1.049GluTyr: 1.049 ± 0.03	0.0GluXaa: 0.0 ± 0.0
Phe	4.541PheAla: 4.541 ± 0.062	0.399PheCys: 0.399 ± 0.019	2.891PheAsp: 2.891 ± 0.055	2.388PheGlu: 2.388 ± 0.05	1.623PhePhe: 1.623 ± 0.041	3.829PheGly: 3.829 ± 0.063	0.772PheHis: 0.772 ± 0.027	2.106PheIle: 2.106 ± 0.052	1.09PheLys: 1.09 ± 0.034	3.386PheLeu: 3.386 ± 0.063	0.938PheMet: 0.938 ± 0.03	1.161PheAsn: 1.161 ± 0.031	1.577PhePro: 1.577 ± 0.038	0.987PheGln: 0.987 ± 0.03	2.267PheArg: 2.267 ± 0.049	2.604PheSer: 2.604 ± 0.051	2.051PheThr: 2.051 ± 0.047	2.831PheVal: 2.831 ± 0.059	0.541PheTrp: 0.541 ± 0.026	0.935PheTyr: 0.935 ± 0.028	0.0PheXaa: 0.0 ± 0.0
Gly	8.977GlyAla: 8.977 ± 0.105	0.793GlyCys: 0.793 ± 0.028	4.851GlyAsp: 4.851 ± 0.075	5.639GlyGlu: 5.639 ± 0.076	3.89GlyPhe: 3.89 ± 0.062	7.596GlyGly: 7.596 ± 0.191	1.937GlyHis: 1.937 ± 0.042	5.134GlyIle: 5.134 ± 0.071	3.703GlyLys: 3.703 ± 0.064	8.501GlyLeu: 8.501 ± 0.101	2.564GlyMet: 2.564 ± 0.056	2.444GlyAsn: 2.444 ± 0.061	3.243GlyPro: 3.243 ± 0.052	2.712GlyGln: 2.712 ± 0.053	5.998GlyArg: 5.998 ± 0.079	5.024GlySer: 5.024 ± 0.086	4.817GlyThr: 4.817 ± 0.083	5.993GlyVal: 5.993 ± 0.087	1.25GlyTrp: 1.25 ± 0.037	2.445GlyTyr: 2.445 ± 0.053	0.0GlyXaa: 0.0 ± 0.0
His	2.199HisAla: 2.199 ± 0.045	0.211HisCys: 0.211 ± 0.016	1.218HisAsp: 1.218 ± 0.038	1.11HisGlu: 1.11 ± 0.03	0.892HisPhe: 0.892 ± 0.03	1.883HisGly: 1.883 ± 0.047	0.541HisHis: 0.541 ± 0.031	1.006HisIle: 1.006 ± 0.031	0.549HisLys: 0.549 ± 0.021	1.948HisLeu: 1.948 ± 0.04	0.516HisMet: 0.516 ± 0.02	0.451HisAsn: 0.451 ± 0.02	1.277HisPro: 1.277 ± 0.039	0.516HisGln: 0.516 ± 0.022	1.272HisArg: 1.272 ± 0.037	1.07HisSer: 1.07 ± 0.034	0.801HisThr: 0.801 ± 0.027	1.543HisVal: 1.543 ± 0.043	0.272HisTrp: 0.272 ± 0.018	0.539HisTyr: 0.539 ± 0.023	0.0HisXaa: 0.0 ± 0.0
Ile	7.755IleAla: 7.755 ± 0.1	0.587IleCys: 0.587 ± 0.025	3.99IleAsp: 3.99 ± 0.06	4.012IleGlu: 4.012 ± 0.071	1.987IlePhe: 1.987 ± 0.046	5.334IleGly: 5.334 ± 0.08	1.011IleHis: 1.011 ± 0.031	2.683IleIle: 2.683 ± 0.059	1.558IleLys: 1.558 ± 0.042	4.926IleLeu: 4.926 ± 0.078	1.147IleMet: 1.147 ± 0.029	1.629IleAsn: 1.629 ± 0.044	2.44IlePro: 2.44 ± 0.044	1.193IleGln: 1.193 ± 0.037	3.691IleArg: 3.691 ± 0.056	3.496IleSer: 3.496 ± 0.058	2.901IleThr: 2.901 ± 0.054	4.468IleVal: 4.468 ± 0.07	0.624IleTrp: 0.624 ± 0.024	1.27IleTyr: 1.27 ± 0.035	0.0IleXaa: 0.0 ± 0.0
Lys	4.594LysAla: 4.594 ± 0.066	0.179LysCys: 0.179 ± 0.013	1.917LysAsp: 1.917 ± 0.049	1.713LysGlu: 1.713 ± 0.051	1.001LysPhe: 1.001 ± 0.028	2.811LysGly: 2.811 ± 0.055	0.661LysHis: 0.661 ± 0.025	2.06LysIle: 2.06 ± 0.043	1.497LysLys: 1.497 ± 0.045	3.52LysLeu: 3.52 ± 0.055	0.947LysMet: 0.947 ± 0.031	0.953LysAsn: 0.953 ± 0.029	2.184LysPro: 2.184 ± 0.045	0.984LysGln: 0.984 ± 0.033	2.446LysArg: 2.446 ± 0.047	2.247LysSer: 2.247 ± 0.048	2.095LysThr: 2.095 ± 0.05	2.604LysVal: 2.604 ± 0.052	0.407LysTrp: 0.407 ± 0.018	0.676LysTyr: 0.676 ± 0.024	0.0LysXaa: 0.0 ± 0.0
Leu	12.275LeuAla: 12.275 ± 0.148	0.812LeuCys: 0.812 ± 0.029	5.902LeuAsp: 5.902 ± 0.082	5.559LeuGlu: 5.559 ± 0.083	3.613LeuPhe: 3.613 ± 0.079	7.99LeuGly: 7.99 ± 0.087	1.598LeuHis: 1.598 ± 0.041	5.069LeuIle: 5.069 ± 0.085	3.838LeuLys: 3.838 ± 0.061	8.439LeuLeu: 8.439 ± 0.141	2.377LeuMet: 2.377 ± 0.047	2.565LeuAsn: 2.565 ± 0.055	4.935LeuPro: 4.935 ± 0.075	2.323LeuGln: 2.323 ± 0.046	5.588LeuArg: 5.588 ± 0.079	6.631LeuSer: 6.631 ± 0.086	5.422LeuThr: 5.422 ± 0.078	7.255LeuVal: 7.255 ± 0.103	0.981LeuTrp: 0.981 ± 0.032	1.99LeuTyr: 1.99 ± 0.038	0.0LeuXaa: 0.0 ± 0.0
Met	3.325MetAla: 3.325 ± 0.052	0.164MetCys: 0.164 ± 0.011	1.325MetAsp: 1.325 ± 0.032	1.399MetGlu: 1.399 ± 0.036	0.787MetPhe: 0.787 ± 0.025	1.959MetGly: 1.959 ± 0.044	0.437MetHis: 0.437 ± 0.017	1.614MetIle: 1.614 ± 0.041	1.168MetLys: 1.168 ± 0.034	2.432MetLeu: 2.432 ± 0.051	0.735MetMet: 0.735 ± 0.027	0.89MetAsn: 0.89 ± 0.028	1.543MetPro: 1.543 ± 0.037	0.808MetGln: 0.808 ± 0.028	1.911MetArg: 1.911 ± 0.042	1.948MetSer: 1.948 ± 0.043	2.038MetThr: 2.038 ± 0.051	1.879MetVal: 1.879 ± 0.04	0.228MetTrp: 0.228 ± 0.014	0.316MetTyr: 0.316 ± 0.019	0.0MetXaa: 0.0 ± 0.0
Asn	3.29AsnAla: 3.29 ± 0.057	0.252AsnCys: 0.252 ± 0.018	1.546AsnAsp: 1.546 ± 0.037	1.531AsnGlu: 1.531 ± 0.039	1.077AsnPhe: 1.077 ± 0.031	2.605AsnGly: 2.605 ± 0.05	0.541AsnHis: 0.541 ± 0.023	1.515AsnIle: 1.515 ± 0.037	0.789AsnLys: 0.789 ± 0.027	2.605AsnLeu: 2.605 ± 0.049	0.769AsnMet: 0.769 ± 0.03	0.761AsnAsn: 0.761 ± 0.027	1.902AsnPro: 1.902 ± 0.049	0.78AsnGln: 0.78 ± 0.03	2.004AsnArg: 2.004 ± 0.039	1.415AsnSer: 1.415 ± 0.044	1.324AsnThr: 1.324 ± 0.035	2.009AsnVal: 2.009 ± 0.046	0.463AsnTrp: 0.463 ± 0.022	0.739AsnTyr: 0.739 ± 0.025	0.0AsnXaa: 0.0 ± 0.0
Pro	5.658ProAla: 5.658 ± 0.094	0.286ProCys: 0.286 ± 0.016	3.812ProAsp: 3.812 ± 0.068	4.055ProGlu: 4.055 ± 0.072	1.968ProPhe: 1.968 ± 0.042	4.348ProGly: 4.348 ± 0.058	1.008ProHis: 1.008 ± 0.034	2.097ProIle: 2.097 ± 0.049	1.638ProLys: 1.638 ± 0.042	4.263ProLeu: 4.263 ± 0.062	1.123ProMet: 1.123 ± 0.037	1.21ProAsn: 1.21 ± 0.033	1.915ProPro: 1.915 ± 0.049	1.391ProGln: 1.391 ± 0.032	2.575ProArg: 2.575 ± 0.049	2.663ProSer: 2.663 ± 0.048	2.123ProThr: 2.123 ± 0.049	4.254ProVal: 4.254 ± 0.067	0.588ProTrp: 0.588 ± 0.022	1.14ProTyr: 1.14 ± 0.034	0.0ProXaa: 0.0 ± 0.0
Gln	3.678GlnAla: 3.678 ± 0.061	0.163GlnCys: 0.163 ± 0.012	1.362GlnAsp: 1.362 ± 0.032	1.424GlnGlu: 1.424 ± 0.042	1.013GlnPhe: 1.013 ± 0.029	2.084GlnGly: 2.084 ± 0.042	0.492GlnHis: 0.492 ± 0.021	1.779GlnIle: 1.779 ± 0.039	1.134GlnLys: 1.134 ± 0.03	2.587GlnLeu: 2.587 ± 0.051	0.914GlnMet: 0.914 ± 0.028	0.782GlnAsn: 0.782 ± 0.03	1.45GlnPro: 1.45 ± 0.038	1.003GlnGln: 1.003 ± 0.038	1.826GlnArg: 1.826 ± 0.042	1.762GlnSer: 1.762 ± 0.055	1.705GlnThr: 1.705 ± 0.033	1.999GlnVal: 1.999 ± 0.048	0.322GlnTrp: 0.322 ± 0.015	0.536GlnTyr: 0.536 ± 0.023	0.0GlnXaa: 0.0 ± 0.0
Arg	6.896ArgAla: 6.896 ± 0.101	0.442ArgCys: 0.442 ± 0.023	4.084ArgAsp: 4.084 ± 0.061	4.305ArgGlu: 4.305 ± 0.067	2.901ArgPhe: 2.901 ± 0.051	4.534ArgGly: 4.534 ± 0.076	1.611ArgHis: 1.611 ± 0.043	4.207ArgIle: 4.207 ± 0.067	2.826ArgLys: 2.826 ± 0.047	7.08ArgLeu: 7.08 ± 0.093	1.997ArgMet: 1.997 ± 0.041	2.032ArgAsn: 2.032 ± 0.042	3.165ArgPro: 3.165 ± 0.061	2.414ArgGln: 2.414 ± 0.043	4.99ArgArg: 4.99 ± 0.084	3.752ArgSer: 3.752 ± 0.065	3.247ArgThr: 3.247 ± 0.048	4.259ArgVal: 4.259 ± 0.061	0.787ArgTrp: 0.787 ± 0.027	1.578ArgTyr: 1.578 ± 0.037	0.0ArgXaa: 0.0 ± 0.0
Ser	6.254SerAla: 6.254 ± 0.091	0.439SerCys: 0.439 ± 0.02	3.434SerAsp: 3.434 ± 0.061	3.392SerGlu: 3.392 ± 0.053	2.378SerPhe: 2.378 ± 0.053	6.207SerGly: 6.207 ± 0.093	1.169SerHis: 1.169 ± 0.033	3.118SerIle: 3.118 ± 0.065	1.744SerLys: 1.744 ± 0.045	5.568SerLeu: 5.568 ± 0.081	1.452SerMet: 1.452 ± 0.036	1.501SerAsn: 1.501 ± 0.043	2.63SerPro: 2.63 ± 0.054	1.631SerGln: 1.631 ± 0.035	3.899SerArg: 3.899 ± 0.071	3.235SerSer: 3.235 ± 0.059	2.787SerThr: 2.787 ± 0.054	4.329SerVal: 4.329 ± 0.082	0.763SerTrp: 0.763 ± 0.026	1.389SerTyr: 1.389 ± 0.037	0.0SerXaa: 0.0 ± 0.0
Thr	6.12ThrAla: 6.12 ± 0.078	0.428ThrCys: 0.428 ± 0.018	3.052ThrAsp: 3.052 ± 0.056	3.034ThrGlu: 3.034 ± 0.056	2.093ThrPhe: 2.093 ± 0.048	5.49ThrGly: 5.49 ± 0.088	0.96ThrHis: 0.96 ± 0.027	3.232ThrIle: 3.232 ± 0.054	1.408ThrLys: 1.408 ± 0.033	5.407ThrLeu: 5.407 ± 0.077	1.287ThrMet: 1.287 ± 0.036	1.406ThrAsn: 1.406 ± 0.041	2.93ThrPro: 2.93 ± 0.053	1.251ThrGln: 1.251 ± 0.035	3.272ThrArg: 3.272 ± 0.053	2.975ThrSer: 2.975 ± 0.057	2.738ThrThr: 2.738 ± 0.056	4.453ThrVal: 4.453 ± 0.073	0.605ThrTrp: 0.605 ± 0.023	1.32ThrTyr: 1.32 ± 0.034	0.0ThrXaa: 0.0 ± 0.0
Val	8.386ValAla: 8.386 ± 0.108	0.639ValCys: 0.639 ± 0.028	4.313ValAsp: 4.313 ± 0.068	4.751ValGlu: 4.751 ± 0.072	2.901ValPhe: 2.901 ± 0.053	5.361ValGly: 5.361 ± 0.074	1.34ValHis: 1.34 ± 0.034	4.39ValIle: 4.39 ± 0.079	2.363ValLys: 2.363 ± 0.052	6.938ValLeu: 6.938 ± 0.106	1.993ValMet: 1.993 ± 0.052	2.084ValAsn: 2.084 ± 0.044	3.54ValPro: 3.54 ± 0.062	1.782ValGln: 1.782 ± 0.044	4.536ValArg: 4.536 ± 0.058	4.77ValSer: 4.77 ± 0.071	4.662ValThr: 4.662 ± 0.076	5.419ValVal: 5.419 ± 0.076	0.801ValTrp: 0.801 ± 0.026	1.517ValTyr: 1.517 ± 0.036	0.0ValXaa: 0.0 ± 0.0
Trp	1.131TrpAla: 1.131 ± 0.032	0.128TrpCys: 0.128 ± 0.011	0.615TrpAsp: 0.615 ± 0.023	0.574TrpGlu: 0.574 ± 0.022	0.552TrpPhe: 0.552 ± 0.019	0.819TrpGly: 0.819 ± 0.028	0.293TrpHis: 0.293 ± 0.016	0.664TrpIle: 0.664 ± 0.023	0.535TrpLys: 0.535 ± 0.023	1.441TrpLeu: 1.441 ± 0.041	0.361TrpMet: 0.361 ± 0.018	0.429TrpAsn: 0.429 ± 0.019	0.676TrpPro: 0.676 ± 0.022	0.505TrpGln: 0.505 ± 0.023	0.945TrpArg: 0.945 ± 0.028	0.745TrpSer: 0.745 ± 0.026	0.697TrpThr: 0.697 ± 0.026	0.755TrpVal: 0.755 ± 0.023	0.177TrpTrp: 0.177 ± 0.013	0.293TrpTyr: 0.293 ± 0.018	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.304TyrAla: 2.304 ± 0.037	0.272TyrCys: 0.272 ± 0.016	1.585TyrAsp: 1.585 ± 0.04	1.385TyrGlu: 1.385 ± 0.041	0.962TyrPhe: 0.962 ± 0.033	2.207TyrGly: 2.207 ± 0.042	0.498TyrHis: 0.498 ± 0.024	0.953TyrIle: 0.953 ± 0.026	0.691TyrLys: 0.691 ± 0.026	2.237TyrLeu: 2.237 ± 0.045	0.517TyrMet: 0.517 ± 0.02	0.643TyrAsn: 0.643 ± 0.024	1.102TyrPro: 1.102 ± 0.033	0.684TyrGln: 0.684 ± 0.021	1.696TyrArg: 1.696 ± 0.043	1.247TyrSer: 1.247 ± 0.036	1.141TyrThr: 1.141 ± 0.029	1.658TyrVal: 1.658 ± 0.042	0.331TyrTrp: 0.331 ± 0.017	0.63TyrTyr: 0.63 ± 0.028	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3469 proteins (1121147 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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