Amino acid dipepetide frequency for Pseudomonas oryzihabitans

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
15.309AlaAla: 15.309 ± 0.139
1.285AlaCys: 1.285 ± 0.031
6.355AlaAsp: 6.355 ± 0.077
7.832AlaGlu: 7.832 ± 0.105
3.965AlaPhe: 3.965 ± 0.051
9.963AlaGly: 9.963 ± 0.098
2.216AlaHis: 2.216 ± 0.041
4.975AlaIle: 4.975 ± 0.065
3.24AlaLys: 3.24 ± 0.06
15.804AlaLeu: 15.804 ± 0.142
2.747AlaMet: 2.747 ± 0.044
2.67AlaAsn: 2.67 ± 0.043
5.512AlaPro: 5.512 ± 0.08
5.534AlaGln: 5.534 ± 0.066
8.553AlaArg: 8.553 ± 0.074
6.073AlaSer: 6.073 ± 0.07
5.709AlaThr: 5.709 ± 0.069
8.096AlaVal: 8.096 ± 0.086
1.782AlaTrp: 1.782 ± 0.038
2.534AlaTyr: 2.534 ± 0.044
0.0AlaXaa: 0.0 ± 0.0
Cys
1.064CysAla: 1.064 ± 0.023
0.132CysCys: 0.132 ± 0.01
0.496CysAsp: 0.496 ± 0.02
0.487CysGlu: 0.487 ± 0.019
0.343CysPhe: 0.343 ± 0.016
0.96CysGly: 0.96 ± 0.024
0.238CysHis: 0.238 ± 0.013
0.382CysIle: 0.382 ± 0.016
0.207CysLys: 0.207 ± 0.012
1.233CysLeu: 1.233 ± 0.031
0.165CysMet: 0.165 ± 0.012
0.233CysAsn: 0.233 ± 0.013
0.476CysPro: 0.476 ± 0.019
0.45CysGln: 0.45 ± 0.019
0.68CysArg: 0.68 ± 0.023
0.537CysSer: 0.537 ± 0.017
0.426CysThr: 0.426 ± 0.019
0.606CysVal: 0.606 ± 0.022
0.162CysTrp: 0.162 ± 0.012
0.255CysTyr: 0.255 ± 0.013
0.0CysXaa: 0.0 ± 0.0
Asp
6.029AspAla: 6.029 ± 0.079
0.502AspCys: 0.502 ± 0.02
2.841AspAsp: 2.841 ± 0.049
3.339AspGlu: 3.339 ± 0.054
2.127AspPhe: 2.127 ± 0.039
4.563AspGly: 4.563 ± 0.06
1.153AspHis: 1.153 ± 0.027
2.399AspIle: 2.399 ± 0.043
1.444AspLys: 1.444 ± 0.036
6.456AspLeu: 6.456 ± 0.077
1.018AspMet: 1.018 ± 0.026
1.317AspAsn: 1.317 ± 0.033
3.045AspPro: 3.045 ± 0.044
2.26AspGln: 2.26 ± 0.039
3.641AspArg: 3.641 ± 0.055
2.697AspSer: 2.697 ± 0.046
2.401AspThr: 2.401 ± 0.037
3.526AspVal: 3.526 ± 0.058
1.031AspTrp: 1.031 ± 0.03
1.604AspTyr: 1.604 ± 0.031
0.0AspXaa: 0.0 ± 0.0
Glu
7.143GluAla: 7.143 ± 0.08
0.394GluCys: 0.394 ± 0.019
2.569GluAsp: 2.569 ± 0.046
3.34GluGlu: 3.34 ± 0.07
1.592GluPhe: 1.592 ± 0.038
4.335GluGly: 4.335 ± 0.062
1.494GluHis: 1.494 ± 0.033
2.609GluIle: 2.609 ± 0.047
1.613GluLys: 1.613 ± 0.043
7.198GluLeu: 7.198 ± 0.083
1.132GluMet: 1.132 ± 0.03
1.261GluAsn: 1.261 ± 0.032
2.716GluPro: 2.716 ± 0.053
3.305GluGln: 3.305 ± 0.058
5.9GluArg: 5.9 ± 0.085
2.4GluSer: 2.4 ± 0.048
2.774GluThr: 2.774 ± 0.048
4.396GluVal: 4.396 ± 0.064
0.727GluTrp: 0.727 ± 0.023
1.009GluTyr: 1.009 ± 0.026
0.0GluXaa: 0.0 ± 0.0
Phe
4.27PheAla: 4.27 ± 0.058
0.44PheCys: 0.44 ± 0.02
2.254PheAsp: 2.254 ± 0.037
1.943PheGlu: 1.943 ± 0.038
1.377PhePhe: 1.377 ± 0.034
3.216PheGly: 3.216 ± 0.057
0.748PheHis: 0.748 ± 0.022
1.612PheIle: 1.612 ± 0.037
1.0PheLys: 1.0 ± 0.029
3.33PheLeu: 3.33 ± 0.06
0.674PheMet: 0.674 ± 0.021
1.08PheAsn: 1.08 ± 0.028
1.408PhePro: 1.408 ± 0.031
1.24PheGln: 1.24 ± 0.034
1.975PheArg: 1.975 ± 0.036
2.101PheSer: 2.101 ± 0.039
1.922PheThr: 1.922 ± 0.036
2.512PheVal: 2.512 ± 0.049
0.568PheTrp: 0.568 ± 0.026
0.951PheTyr: 0.951 ± 0.029
0.0PheXaa: 0.0 ± 0.0
Gly
8.182GlyAla: 8.182 ± 0.091
0.992GlyCys: 0.992 ± 0.024
4.073GlyAsp: 4.073 ± 0.059
5.092GlyGlu: 5.092 ± 0.071
3.377GlyPhe: 3.377 ± 0.054
6.316GlyGly: 6.316 ± 0.079
1.904GlyHis: 1.904 ± 0.041
4.136GlyIle: 4.136 ± 0.059
2.889GlyLys: 2.889 ± 0.046
10.427GlyLeu: 10.427 ± 0.111
2.067GlyMet: 2.067 ± 0.04
2.186GlyAsn: 2.186 ± 0.043
2.894GlyPro: 2.894 ± 0.048
3.974GlyGln: 3.974 ± 0.06
5.93GlyArg: 5.93 ± 0.064
4.474GlySer: 4.474 ± 0.06
3.92GlyThr: 3.92 ± 0.049
6.214GlyVal: 6.214 ± 0.067
1.475GlyTrp: 1.475 ± 0.037
2.618GlyTyr: 2.618 ± 0.047
0.0GlyXaa: 0.0 ± 0.0
His
2.247HisAla: 2.247 ± 0.046
0.304HisCys: 0.304 ± 0.016
1.19HisAsp: 1.19 ± 0.033
1.179HisGlu: 1.179 ± 0.031
0.897HisPhe: 0.897 ± 0.028
2.077HisGly: 2.077 ± 0.038
0.582HisHis: 0.582 ± 0.023
0.753HisIle: 0.753 ± 0.022
0.457HisLys: 0.457 ± 0.018
2.772HisLeu: 2.772 ± 0.048
0.385HisMet: 0.385 ± 0.016
0.538HisAsn: 0.538 ± 0.019
1.493HisPro: 1.493 ± 0.036
0.964HisGln: 0.964 ± 0.03
1.497HisArg: 1.497 ± 0.036
1.071HisSer: 1.071 ± 0.027
0.878HisThr: 0.878 ± 0.023
1.274HisVal: 1.274 ± 0.028
0.444HisTrp: 0.444 ± 0.021
0.701HisTyr: 0.701 ± 0.021
0.0HisXaa: 0.0 ± 0.0
Ile
5.813IleAla: 5.813 ± 0.067
0.438IleCys: 0.438 ± 0.02
2.757IleAsp: 2.757 ± 0.044
2.849IleGlu: 2.849 ± 0.049
1.251IlePhe: 1.251 ± 0.034
4.231IleGly: 4.231 ± 0.067
0.882IleHis: 0.882 ± 0.022
1.602IleIle: 1.602 ± 0.042
1.322IleLys: 1.322 ± 0.03
4.175IleLeu: 4.175 ± 0.062
0.667IleMet: 0.667 ± 0.023
1.345IleAsn: 1.345 ± 0.033
2.072IlePro: 2.072 ± 0.039
1.622IleGln: 1.622 ± 0.038
2.905IleArg: 2.905 ± 0.047
2.209IleSer: 2.209 ± 0.047
2.263IleThr: 2.263 ± 0.039
2.899IleVal: 2.899 ± 0.044
0.437IleTrp: 0.437 ± 0.018
0.925IleTyr: 0.925 ± 0.025
0.0IleXaa: 0.0 ± 0.0
Lys
3.644LysAla: 3.644 ± 0.067
0.133LysCys: 0.133 ± 0.01
1.459LysAsp: 1.459 ± 0.035
1.275LysGlu: 1.275 ± 0.033
0.678LysPhe: 0.678 ± 0.025
2.28LysGly: 2.28 ± 0.044
0.547LysHis: 0.547 ± 0.02
1.149LysIle: 1.149 ± 0.034
0.996LysLys: 0.996 ± 0.029
2.933LysLeu: 2.933 ± 0.052
0.524LysMet: 0.524 ± 0.023
0.67LysAsn: 0.67 ± 0.025
1.779LysPro: 1.779 ± 0.04
1.261LysGln: 1.261 ± 0.036
2.016LysArg: 2.016 ± 0.043
1.356LysSer: 1.356 ± 0.031
1.579LysThr: 1.579 ± 0.043
2.367LysVal: 2.367 ± 0.045
0.26LysTrp: 0.26 ± 0.014
0.535LysTyr: 0.535 ± 0.026
0.0LysXaa: 0.0 ± 0.0
Leu
17.284LeuAla: 17.284 ± 0.154
1.258LeuCys: 1.258 ± 0.032
7.68LeuAsp: 7.68 ± 0.104
7.122LeuGlu: 7.122 ± 0.099
4.171LeuPhe: 4.171 ± 0.066
10.731LeuGly: 10.731 ± 0.129
2.569LeuHis: 2.569 ± 0.04
5.212LeuIle: 5.212 ± 0.071
3.631LeuLys: 3.631 ± 0.057
15.244LeuLeu: 15.244 ± 0.164
2.315LeuMet: 2.315 ± 0.037
2.982LeuAsn: 2.982 ± 0.049
7.036LeuPro: 7.036 ± 0.081
4.954LeuGln: 4.954 ± 0.069
8.335LeuArg: 8.335 ± 0.091
6.582LeuSer: 6.582 ± 0.071
6.197LeuThr: 6.197 ± 0.071
8.807LeuVal: 8.807 ± 0.101
1.489LeuTrp: 1.489 ± 0.037
2.662LeuTyr: 2.662 ± 0.049
0.0LeuXaa: 0.0 ± 0.0
Met
2.473MetAla: 2.473 ± 0.044
0.123MetCys: 0.123 ± 0.01
0.891MetAsp: 0.891 ± 0.029
0.848MetGlu: 0.848 ± 0.026
0.539MetPhe: 0.539 ± 0.022
1.463MetGly: 1.463 ± 0.036
0.438MetHis: 0.438 ± 0.02
0.889MetIle: 0.889 ± 0.027
0.703MetLys: 0.703 ± 0.021
2.333MetLeu: 2.333 ± 0.047
0.388MetMet: 0.388 ± 0.021
0.716MetAsn: 0.716 ± 0.025
1.172MetPro: 1.172 ± 0.028
0.951MetGln: 0.951 ± 0.029
1.318MetArg: 1.318 ± 0.032
1.439MetSer: 1.439 ± 0.031
1.37MetThr: 1.37 ± 0.033
1.39MetVal: 1.39 ± 0.035
0.124MetTrp: 0.124 ± 0.01
0.27MetTyr: 0.27 ± 0.015
0.0MetXaa: 0.0 ± 0.0
Asn
2.879AsnAla: 2.879 ± 0.049
0.226AsnCys: 0.226 ± 0.013
1.294AsnAsp: 1.294 ± 0.026
1.181AsnGlu: 1.181 ± 0.031
0.899AsnPhe: 0.899 ± 0.027
2.202AsnGly: 2.202 ± 0.045
0.506AsnHis: 0.506 ± 0.02
1.023AsnIle: 1.023 ± 0.03
0.637AsnLys: 0.637 ± 0.026
3.177AsnLeu: 3.177 ± 0.049
0.464AsnMet: 0.464 ± 0.017
0.631AsnAsn: 0.631 ± 0.022
1.623AsnPro: 1.623 ± 0.039
1.037AsnGln: 1.037 ± 0.031
1.788AsnArg: 1.788 ± 0.04
1.177AsnSer: 1.177 ± 0.03
1.185AsnThr: 1.185 ± 0.032
1.719AsnVal: 1.719 ± 0.036
0.379AsnTrp: 0.379 ± 0.015
0.67AsnTyr: 0.67 ± 0.022
0.0AsnXaa: 0.0 ± 0.0
Pro
6.479ProAla: 6.479 ± 0.078
0.363ProCys: 0.363 ± 0.015
2.955ProAsp: 2.955 ± 0.05
3.668ProGlu: 3.668 ± 0.061
1.787ProPhe: 1.787 ± 0.033
4.385ProGly: 4.385 ± 0.054
1.089ProHis: 1.089 ± 0.032
1.82ProIle: 1.82 ± 0.036
1.307ProLys: 1.307 ± 0.034
6.468ProLeu: 6.468 ± 0.084
1.022ProMet: 1.022 ± 0.026
1.211ProAsn: 1.211 ± 0.029
2.267ProPro: 2.267 ± 0.05
2.158ProGln: 2.158 ± 0.043
3.155ProArg: 3.155 ± 0.049
2.456ProSer: 2.456 ± 0.041
2.492ProThr: 2.492 ± 0.041
3.95ProVal: 3.95 ± 0.063
0.77ProTrp: 0.77 ± 0.025
1.223ProTyr: 1.223 ± 0.031
0.0ProXaa: 0.0 ± 0.0
Gln
6.512GlnAla: 6.512 ± 0.082
0.257GlnCys: 0.257 ± 0.012
2.023GlnAsp: 2.023 ± 0.039
2.117GlnGlu: 2.117 ± 0.039
1.124GlnPhe: 1.124 ± 0.025
4.067GlnGly: 4.067 ± 0.055
0.96GlnHis: 0.96 ± 0.023
1.789GlnIle: 1.789 ± 0.036
0.979GlnLys: 0.979 ± 0.032
5.733GlnLeu: 5.733 ± 0.069
0.782GlnMet: 0.782 ± 0.026
0.923GlnAsn: 0.923 ± 0.024
2.711GlnPro: 2.711 ± 0.043
2.541GlnGln: 2.541 ± 0.048
4.217GlnArg: 4.217 ± 0.071
1.884GlnSer: 1.884 ± 0.037
2.015GlnThr: 2.015 ± 0.04
3.709GlnVal: 3.709 ± 0.051
0.579GlnTrp: 0.579 ± 0.02
0.812GlnTyr: 0.812 ± 0.024
0.0GlnXaa: 0.0 ± 0.0
Arg
6.907ArgAla: 6.907 ± 0.067
0.679ArgCys: 0.679 ± 0.025
3.875ArgAsp: 3.875 ± 0.059
4.693ArgGlu: 4.693 ± 0.061
2.859ArgPhe: 2.859 ± 0.049
4.622ArgGly: 4.622 ± 0.058
1.968ArgHis: 1.968 ± 0.036
3.49ArgIle: 3.49 ± 0.053
1.767ArgLys: 1.767 ± 0.037
10.78ArgLeu: 10.78 ± 0.132
1.468ArgMet: 1.468 ± 0.032
1.743ArgAsn: 1.743 ± 0.039
3.407ArgPro: 3.407 ± 0.051
4.398ArgGln: 4.398 ± 0.062
5.609ArgArg: 5.609 ± 0.079
3.432ArgSer: 3.432 ± 0.058
3.107ArgThr: 3.107 ± 0.047
4.581ArgVal: 4.581 ± 0.053
1.22ArgTrp: 1.22 ± 0.032
2.205ArgTyr: 2.205 ± 0.036
0.0ArgXaa: 0.0 ± 0.0
Ser
5.701SerAla: 5.701 ± 0.065
0.476SerCys: 0.476 ± 0.02
2.494SerAsp: 2.494 ± 0.047
2.548SerGlu: 2.548 ± 0.045
1.93SerPhe: 1.93 ± 0.042
4.964SerGly: 4.964 ± 0.058
1.121SerHis: 1.121 ± 0.026
2.151SerIle: 2.151 ± 0.042
1.275SerLys: 1.275 ± 0.034
6.758SerLeu: 6.758 ± 0.087
1.111SerMet: 1.111 ± 0.028
1.298SerAsn: 1.298 ± 0.03
2.566SerPro: 2.566 ± 0.046
2.172SerGln: 2.172 ± 0.04
3.668SerArg: 3.668 ± 0.049
2.839SerSer: 2.839 ± 0.062
2.501SerThr: 2.501 ± 0.049
3.37SerVal: 3.37 ± 0.049
0.726SerTrp: 0.726 ± 0.023
1.373SerTyr: 1.373 ± 0.034
0.0SerXaa: 0.0 ± 0.0
Thr
5.805ThrAla: 5.805 ± 0.078
0.416ThrCys: 0.416 ± 0.017
2.333ThrAsp: 2.333 ± 0.044
2.298ThrGlu: 2.298 ± 0.042
1.762ThrPhe: 1.762 ± 0.035
4.321ThrGly: 4.321 ± 0.061
1.001ThrHis: 1.001 ± 0.03
1.67ThrIle: 1.67 ± 0.038
1.028ThrLys: 1.028 ± 0.027
7.395ThrLeu: 7.395 ± 0.074
0.746ThrMet: 0.746 ± 0.026
1.049ThrAsn: 1.049 ± 0.033
3.408ThrPro: 3.408 ± 0.048
1.97ThrGln: 1.97 ± 0.039
3.474ThrArg: 3.474 ± 0.047
2.457ThrSer: 2.457 ± 0.044
2.509ThrThr: 2.509 ± 0.047
3.358ThrVal: 3.358 ± 0.052
0.711ThrTrp: 0.711 ± 0.024
1.172ThrTyr: 1.172 ± 0.03
0.0ThrXaa: 0.0 ± 0.0
Val
8.571ValAla: 8.571 ± 0.094
0.697ValCys: 0.697 ± 0.023
3.921ValAsp: 3.921 ± 0.058
4.403ValGlu: 4.403 ± 0.059
2.489ValPhe: 2.489 ± 0.044
5.4ValGly: 5.4 ± 0.077
1.34ValHis: 1.34 ± 0.026
3.593ValIle: 3.593 ± 0.057
2.074ValLys: 2.074 ± 0.048
8.54ValLeu: 8.54 ± 0.096
1.519ValMet: 1.519 ± 0.037
1.837ValAsn: 1.837 ± 0.042
3.404ValPro: 3.404 ± 0.046
2.726ValGln: 2.726 ± 0.049
4.698ValArg: 4.698 ± 0.062
3.803ValSer: 3.803 ± 0.06
3.875ValThr: 3.875 ± 0.061
5.638ValVal: 5.638 ± 0.076
0.848ValTrp: 0.848 ± 0.025
1.482ValTyr: 1.482 ± 0.033
0.0ValXaa: 0.0 ± 0.0
Trp
1.198TrpAla: 1.198 ± 0.029
0.159TrpCys: 0.159 ± 0.011
0.623TrpAsp: 0.623 ± 0.023
0.582TrpGlu: 0.582 ± 0.022
0.53TrpPhe: 0.53 ± 0.021
0.894TrpGly: 0.894 ± 0.029
0.385TrpHis: 0.385 ± 0.018
0.65TrpIle: 0.65 ± 0.022
0.364TrpLys: 0.364 ± 0.017
2.321TrpLeu: 2.321 ± 0.044
0.289TrpMet: 0.289 ± 0.014
0.423TrpAsn: 0.423 ± 0.02
0.758TrpPro: 0.758 ± 0.028
0.995TrpGln: 0.995 ± 0.03
1.272TrpArg: 1.272 ± 0.034
0.814TrpSer: 0.814 ± 0.027
0.684TrpThr: 0.684 ± 0.025
0.857TrpVal: 0.857 ± 0.026
0.227TrpTrp: 0.227 ± 0.016
0.313TrpTyr: 0.313 ± 0.016
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.643TyrAla: 2.643 ± 0.048
0.26TyrCys: 0.26 ± 0.013
1.311TyrAsp: 1.311 ± 0.031
1.109TyrGlu: 1.109 ± 0.032
0.923TyrPhe: 0.923 ± 0.029
2.15TyrGly: 2.15 ± 0.047
0.565TyrHis: 0.565 ± 0.023
0.759TyrIle: 0.759 ± 0.027
0.505TyrLys: 0.505 ± 0.018
3.182TyrLeu: 3.182 ± 0.049
0.354TyrMet: 0.354 ± 0.016
0.582TyrAsn: 0.582 ± 0.024
1.277TyrPro: 1.277 ± 0.029
1.221TyrGln: 1.221 ± 0.031
2.18TyrArg: 2.18 ± 0.039
1.243TyrSer: 1.243 ± 0.036
1.079TyrThr: 1.079 ± 0.028
1.589TyrVal: 1.589 ± 0.038
0.382TyrTrp: 0.382 ± 0.017
0.639TyrTyr: 0.639 ± 0.023
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4281 proteins (1409937 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski