Amino acid dipepetide frequency for Ascodesmis nigricans

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.433AlaAla: 8.433 ± 0.066	0.915AlaCys: 0.915 ± 0.015	3.601AlaAsp: 3.601 ± 0.035	5.04AlaGlu: 5.04 ± 0.05	2.623AlaPhe: 2.623 ± 0.029	5.496AlaGly: 5.496 ± 0.043	1.724AlaHis: 1.724 ± 0.023	3.757AlaIle: 3.757 ± 0.033	3.905AlaLys: 3.905 ± 0.036	7.067AlaLeu: 7.067 ± 0.05	1.878AlaMet: 1.878 ± 0.024	2.498AlaAsn: 2.498 ± 0.027	5.365AlaPro: 5.365 ± 0.052	2.869AlaGln: 2.869 ± 0.031	4.802AlaArg: 4.802 ± 0.04	6.465AlaSer: 6.465 ± 0.051	5.109AlaThr: 5.109 ± 0.041	5.382AlaVal: 5.382 ± 0.043	0.97AlaTrp: 0.97 ± 0.016	1.817AlaTyr: 1.817 ± 0.023	0.0AlaXaa: 0.0 ± 0.0
Cys	0.867CysAla: 0.867 ± 0.013	0.324CysCys: 0.324 ± 0.011	0.657CysAsp: 0.657 ± 0.013	0.652CysGlu: 0.652 ± 0.016	0.533CysPhe: 0.533 ± 0.015	1.065CysGly: 1.065 ± 0.022	0.351CysHis: 0.351 ± 0.011	0.662CysIle: 0.662 ± 0.013	0.5CysLys: 0.5 ± 0.013	1.145CysLeu: 1.145 ± 0.019	0.282CysMet: 0.282 ± 0.008	0.445CysAsn: 0.445 ± 0.011	0.71CysPro: 0.71 ± 0.015	0.384CysGln: 0.384 ± 0.011	0.795CysArg: 0.795 ± 0.016	0.89CysSer: 0.89 ± 0.016	0.692CysThr: 0.692 ± 0.014	0.824CysVal: 0.824 ± 0.016	0.231CysTrp: 0.231 ± 0.007	0.355CysTyr: 0.355 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	4.164AspAla: 4.164 ± 0.036	0.594AspCys: 0.594 ± 0.012	4.339AspAsp: 4.339 ± 0.052	4.567AspGlu: 4.567 ± 0.044	1.885AspPhe: 1.885 ± 0.021	3.9AspGly: 3.9 ± 0.038	1.201AspHis: 1.201 ± 0.018	2.795AspIle: 2.795 ± 0.03	2.145AspLys: 2.145 ± 0.023	4.486AspLeu: 4.486 ± 0.038	1.22AspMet: 1.22 ± 0.016	1.745AspAsn: 1.745 ± 0.025	3.308AspPro: 3.308 ± 0.034	1.52AspGln: 1.52 ± 0.021	2.771AspArg: 2.771 ± 0.031	3.781AspSer: 3.781 ± 0.034	2.937AspThr: 2.937 ± 0.03	3.515AspVal: 3.515 ± 0.033	0.769AspTrp: 0.769 ± 0.015	1.503AspTyr: 1.503 ± 0.023	0.0AspXaa: 0.0 ± 0.0
Glu	5.097GluAla: 5.097 ± 0.051	0.675GluCys: 0.675 ± 0.014	4.194GluAsp: 4.194 ± 0.041	7.104GluGlu: 7.104 ± 0.083	1.992GluPhe: 1.992 ± 0.021	4.29GluGly: 4.29 ± 0.035	1.38GluHis: 1.38 ± 0.02	3.071GluIle: 3.071 ± 0.03	4.726GluLys: 4.726 ± 0.048	5.395GluLeu: 5.395 ± 0.049	1.801GluMet: 1.801 ± 0.026	2.325GluAsn: 2.325 ± 0.024	2.711GluPro: 2.711 ± 0.035	2.305GluGln: 2.305 ± 0.024	4.677GluArg: 4.677 ± 0.042	4.143GluSer: 4.143 ± 0.037	3.539GluThr: 3.539 ± 0.029	4.074GluVal: 4.074 ± 0.035	0.998GluTrp: 0.998 ± 0.016	1.673GluTyr: 1.673 ± 0.021	0.0GluXaa: 0.0 ± 0.0
Phe	2.603PheAla: 2.603 ± 0.03	0.562PheCys: 0.562 ± 0.015	1.977PheAsp: 1.977 ± 0.025	2.002PheGlu: 2.002 ± 0.022	1.594PhePhe: 1.594 ± 0.028	2.514PheGly: 2.514 ± 0.033	0.925PheHis: 0.925 ± 0.015	1.68PheIle: 1.68 ± 0.022	1.418PheLys: 1.418 ± 0.018	3.324PheLeu: 3.324 ± 0.036	0.738PheMet: 0.738 ± 0.013	1.269PheAsn: 1.269 ± 0.018	2.059PhePro: 2.059 ± 0.027	1.178PheGln: 1.178 ± 0.017	1.944PheArg: 1.944 ± 0.024	2.927PheSer: 2.927 ± 0.025	2.238PheThr: 2.238 ± 0.026	2.168PheVal: 2.168 ± 0.025	0.563PheTrp: 0.563 ± 0.011	0.998PheTyr: 0.998 ± 0.017	0.0PheXaa: 0.0 ± 0.0
Gly	4.928GlyAla: 4.928 ± 0.039	0.883GlyCys: 0.883 ± 0.018	3.564GlyAsp: 3.564 ± 0.031	4.505GlyGlu: 4.505 ± 0.043	2.611GlyPhe: 2.611 ± 0.025	6.65GlyGly: 6.65 ± 0.071	1.565GlyHis: 1.565 ± 0.02	3.323GlyIle: 3.323 ± 0.029	3.874GlyLys: 3.874 ± 0.038	5.525GlyLeu: 5.525 ± 0.047	1.821GlyMet: 1.821 ± 0.023	2.4GlyAsn: 2.4 ± 0.028	2.95GlyPro: 2.95 ± 0.029	2.048GlyGln: 2.048 ± 0.025	4.501GlyArg: 4.501 ± 0.04	5.263GlySer: 5.263 ± 0.053	3.725GlyThr: 3.725 ± 0.034	4.801GlyVal: 4.801 ± 0.04	1.211GlyTrp: 1.211 ± 0.019	2.028GlyTyr: 2.028 ± 0.028	0.0GlyXaa: 0.0 ± 0.0
His	1.734HisAla: 1.734 ± 0.021	0.374HisCys: 0.374 ± 0.009	1.301HisAsp: 1.301 ± 0.021	1.253HisGlu: 1.253 ± 0.022	0.896HisPhe: 0.896 ± 0.016	1.667HisGly: 1.667 ± 0.023	1.553HisHis: 1.553 ± 0.036	1.283HisIle: 1.283 ± 0.019	0.944HisLys: 0.944 ± 0.016	2.456HisLeu: 2.456 ± 0.028	0.451HisMet: 0.451 ± 0.01	0.92HisAsn: 0.92 ± 0.014	2.217HisPro: 2.217 ± 0.032	1.193HisGln: 1.193 ± 0.021	1.86HisArg: 1.86 ± 0.023	2.03HisSer: 2.03 ± 0.028	1.57HisThr: 1.57 ± 0.021	1.336HisVal: 1.336 ± 0.018	0.313HisTrp: 0.313 ± 0.008	0.731HisTyr: 0.731 ± 0.014	0.0HisXaa: 0.0 ± 0.0
Ile	3.88IleAla: 3.88 ± 0.04	0.671IleCys: 0.671 ± 0.016	2.628IleAsp: 2.628 ± 0.027	2.752IleGlu: 2.752 ± 0.032	1.805IlePhe: 1.805 ± 0.023	2.9IleGly: 2.9 ± 0.033	1.311IleHis: 1.311 ± 0.018	2.506IleIle: 2.506 ± 0.028	2.181IleLys: 2.181 ± 0.022	4.341IleLeu: 4.341 ± 0.04	0.983IleMet: 0.983 ± 0.016	1.704IleAsn: 1.704 ± 0.021	3.523IlePro: 3.523 ± 0.031	1.77IleGln: 1.77 ± 0.024	2.838IleArg: 2.838 ± 0.03	3.796IleSer: 3.796 ± 0.032	3.189IleThr: 3.189 ± 0.029	2.986IleVal: 2.986 ± 0.033	0.626IleTrp: 0.626 ± 0.013	1.271IleTyr: 1.271 ± 0.02	0.0IleXaa: 0.0 ± 0.0
Lys	4.108LysAla: 4.108 ± 0.041	0.558LysCys: 0.558 ± 0.013	2.71LysAsp: 2.71 ± 0.029	4.156LysGlu: 4.156 ± 0.045	1.483LysPhe: 1.483 ± 0.021	3.057LysGly: 3.057 ± 0.032	1.141LysHis: 1.141 ± 0.019	2.41LysIle: 2.41 ± 0.027	4.366LysLys: 4.366 ± 0.057	4.175LysLeu: 4.175 ± 0.036	1.2LysMet: 1.2 ± 0.019	1.846LysAsn: 1.846 ± 0.022	2.995LysPro: 2.995 ± 0.036	1.81LysGln: 1.81 ± 0.023	3.907LysArg: 3.907 ± 0.034	3.552LysSer: 3.552 ± 0.034	3.011LysThr: 3.011 ± 0.031	2.973LysVal: 2.973 ± 0.029	0.682LysTrp: 0.682 ± 0.014	1.319LysTyr: 1.319 ± 0.028	0.0LysXaa: 0.0 ± 0.0
Leu	6.836LeuAla: 6.836 ± 0.049	1.156LeuCys: 1.156 ± 0.019	4.663LeuAsp: 4.663 ± 0.043	5.551LeuGlu: 5.551 ± 0.048	3.149LeuPhe: 3.149 ± 0.031	5.438LeuGly: 5.438 ± 0.041	2.503LeuHis: 2.503 ± 0.029	3.728LeuIle: 3.728 ± 0.04	4.301LeuLys: 4.301 ± 0.042	8.513LeuLeu: 8.513 ± 0.072	1.767LeuMet: 1.767 ± 0.022	2.958LeuAsn: 2.958 ± 0.028	6.009LeuPro: 6.009 ± 0.049	3.501LeuGln: 3.501 ± 0.034	5.74LeuArg: 5.74 ± 0.043	7.155LeuSer: 7.155 ± 0.045	5.058LeuThr: 5.058 ± 0.041	5.083LeuVal: 5.083 ± 0.045	1.111LeuTrp: 1.111 ± 0.016	2.198LeuTyr: 2.198 ± 0.027	0.0LeuXaa: 0.0 ± 0.0
Met	2.028MetAla: 2.028 ± 0.024	0.27MetCys: 0.27 ± 0.008	1.278MetAsp: 1.278 ± 0.02	1.619MetGlu: 1.619 ± 0.025	0.754MetPhe: 0.754 ± 0.013	1.699MetGly: 1.699 ± 0.023	0.442MetHis: 0.442 ± 0.012	0.964MetIle: 0.964 ± 0.017	1.213MetLys: 1.213 ± 0.018	1.82MetLeu: 1.82 ± 0.021	0.713MetMet: 0.713 ± 0.013	0.785MetAsn: 0.785 ± 0.015	1.244MetPro: 1.244 ± 0.019	0.728MetGln: 0.728 ± 0.014	1.359MetArg: 1.359 ± 0.021	1.835MetSer: 1.835 ± 0.021	1.29MetThr: 1.29 ± 0.018	1.472MetVal: 1.472 ± 0.018	0.283MetTrp: 0.283 ± 0.008	0.513MetTyr: 0.513 ± 0.012	0.0MetXaa: 0.0 ± 0.0
Asn	2.711AsnAla: 2.711 ± 0.025	0.425AsnCys: 0.425 ± 0.011	1.853AsnAsp: 1.853 ± 0.022	1.924AsnGlu: 1.924 ± 0.021	1.215AsnPhe: 1.215 ± 0.015	2.621AsnGly: 2.621 ± 0.03	0.968AsnHis: 0.968 ± 0.015	1.935AsnIle: 1.935 ± 0.027	1.466AsnLys: 1.466 ± 0.021	3.065AsnLeu: 3.065 ± 0.032	0.778AsnMet: 0.778 ± 0.016	1.543AsnAsn: 1.543 ± 0.032	2.728AsnPro: 2.728 ± 0.033	1.228AsnGln: 1.228 ± 0.018	1.989AsnArg: 1.989 ± 0.022	2.667AsnSer: 2.667 ± 0.027	2.377AsnThr: 2.377 ± 0.026	2.134AsnVal: 2.134 ± 0.023	0.506AsnTrp: 0.506 ± 0.012	0.935AsnTyr: 0.935 ± 0.017	0.0AsnXaa: 0.0 ± 0.0
Pro	5.613ProAla: 5.613 ± 0.044	0.546ProCys: 0.546 ± 0.014	2.984ProAsp: 2.984 ± 0.029	4.015ProGlu: 4.015 ± 0.035	1.978ProPhe: 1.978 ± 0.027	3.994ProGly: 3.994 ± 0.036	1.867ProHis: 1.867 ± 0.029	2.837ProIle: 2.837 ± 0.027	2.975ProLys: 2.975 ± 0.032	5.21ProLeu: 5.21 ± 0.038	1.112ProMet: 1.112 ± 0.018	2.319ProAsn: 2.319 ± 0.03	8.26ProPro: 8.26 ± 0.126	2.826ProGln: 2.826 ± 0.042	3.876ProArg: 3.876 ± 0.039	7.064ProSer: 7.064 ± 0.07	5.12ProThr: 5.12 ± 0.043	3.824ProVal: 3.824 ± 0.04	0.658ProTrp: 0.658 ± 0.014	1.498ProTyr: 1.498 ± 0.021	0.0ProXaa: 0.0 ± 0.0
Gln	2.736GlnAla: 2.736 ± 0.033	0.422GlnCys: 0.422 ± 0.012	1.584GlnAsp: 1.584 ± 0.021	2.204GlnGlu: 2.204 ± 0.025	1.153GlnPhe: 1.153 ± 0.018	1.939GlnGly: 1.939 ± 0.024	1.261GlnHis: 1.261 ± 0.024	1.701GlnIle: 1.701 ± 0.024	2.042GlnLys: 2.042 ± 0.028	3.233GlnLeu: 3.233 ± 0.029	0.859GlnMet: 0.859 ± 0.016	1.412GlnAsn: 1.412 ± 0.021	2.624GlnPro: 2.624 ± 0.039	2.946GlnGln: 2.946 ± 0.079	2.604GlnArg: 2.604 ± 0.03	2.724GlnSer: 2.724 ± 0.03	2.117GlnThr: 2.117 ± 0.025	1.853GlnVal: 1.853 ± 0.022	0.483GlnTrp: 0.483 ± 0.011	1.045GlnTyr: 1.045 ± 0.017	0.0GlnXaa: 0.0 ± 0.0
Arg	4.471ArgAla: 4.471 ± 0.036	0.866ArgCys: 0.866 ± 0.017	3.218ArgAsp: 3.218 ± 0.035	4.612ArgGlu: 4.612 ± 0.045	2.198ArgPhe: 2.198 ± 0.026	4.252ArgGly: 4.252 ± 0.04	1.678ArgHis: 1.678 ± 0.024	3.074ArgIle: 3.074 ± 0.031	4.01ArgLys: 4.01 ± 0.038	5.355ArgLeu: 5.355 ± 0.044	1.476ArgMet: 1.476 ± 0.017	2.361ArgAsn: 2.361 ± 0.027	3.788ArgPro: 3.788 ± 0.038	2.349ArgGln: 2.349 ± 0.027	6.073ArgArg: 6.073 ± 0.057	4.836ArgSer: 4.836 ± 0.042	3.441ArgThr: 3.441 ± 0.03	3.675ArgVal: 3.675 ± 0.032	1.016ArgTrp: 1.016 ± 0.017	1.734ArgTyr: 1.734 ± 0.025	0.0ArgXaa: 0.0 ± 0.0
Ser	6.42SerAla: 6.42 ± 0.051	0.869SerCys: 0.869 ± 0.016	3.943SerAsp: 3.943 ± 0.036	3.967SerGlu: 3.967 ± 0.036	2.799SerPhe: 2.799 ± 0.027	5.416SerGly: 5.416 ± 0.042	2.101SerHis: 2.101 ± 0.029	3.841SerIle: 3.841 ± 0.032	3.432SerLys: 3.432 ± 0.033	6.846SerLeu: 6.846 ± 0.048	1.57SerMet: 1.57 ± 0.023	2.762SerAsn: 2.762 ± 0.029	6.782SerPro: 6.782 ± 0.068	2.808SerGln: 2.808 ± 0.027	4.987SerArg: 4.987 ± 0.055	10.056SerSer: 10.056 ± 0.1	6.425SerThr: 6.425 ± 0.053	4.324SerVal: 4.324 ± 0.031	0.934SerTrp: 0.934 ± 0.017	1.871SerTyr: 1.871 ± 0.021	0.0SerXaa: 0.0 ± 0.0
Thr	5.445ThrAla: 5.445 ± 0.039	0.727ThrCys: 0.727 ± 0.014	2.681ThrAsp: 2.681 ± 0.025	3.182ThrGlu: 3.182 ± 0.032	2.148ThrPhe: 2.148 ± 0.025	4.079ThrGly: 4.079 ± 0.035	1.626ThrHis: 1.626 ± 0.024	3.273ThrIle: 3.273 ± 0.028	2.756ThrLys: 2.756 ± 0.028	5.501ThrLeu: 5.501 ± 0.042	1.184ThrMet: 1.184 ± 0.017	2.11ThrAsn: 2.11 ± 0.026	5.758ThrPro: 5.758 ± 0.047	2.007ThrGln: 2.007 ± 0.022	3.332ThrArg: 3.332 ± 0.031	5.815ThrSer: 5.815 ± 0.042	5.778ThrThr: 5.778 ± 0.067	3.783ThrVal: 3.783 ± 0.036	0.751ThrTrp: 0.751 ± 0.015	1.493ThrTyr: 1.493 ± 0.019	0.0ThrXaa: 0.0 ± 0.0
Val	4.834ValAla: 4.834 ± 0.037	0.865ValCys: 0.865 ± 0.016	3.603ValAsp: 3.603 ± 0.034	4.642ValGlu: 4.642 ± 0.042	2.333ValPhe: 2.333 ± 0.029	4.303ValGly: 4.303 ± 0.038	1.344ValHis: 1.344 ± 0.019	2.79ValIle: 2.79 ± 0.026	3.294ValLys: 3.294 ± 0.032	5.431ValLeu: 5.431 ± 0.039	1.536ValMet: 1.536 ± 0.022	2.054ValAsn: 2.054 ± 0.022	3.493ValPro: 3.493 ± 0.035	2.039ValGln: 2.039 ± 0.024	3.758ValArg: 3.758 ± 0.035	4.35ValSer: 4.35 ± 0.037	3.386ValThr: 3.386 ± 0.034	4.932ValVal: 4.932 ± 0.05	0.912ValTrp: 0.912 ± 0.015	1.655ValTyr: 1.655 ± 0.016	0.0ValXaa: 0.0 ± 0.0
Trp	0.981TrpAla: 0.981 ± 0.017	0.235TrpCys: 0.235 ± 0.009	0.854TrpAsp: 0.854 ± 0.018	0.942TrpGlu: 0.942 ± 0.019	0.485TrpPhe: 0.485 ± 0.012	1.017TrpGly: 1.017 ± 0.016	0.295TrpHis: 0.295 ± 0.009	0.69TrpIle: 0.69 ± 0.014	0.836TrpLys: 0.836 ± 0.011	1.13TrpLeu: 1.13 ± 0.019	0.385TrpMet: 0.385 ± 0.01	0.561TrpAsn: 0.561 ± 0.012	0.52TrpPro: 0.52 ± 0.013	0.395TrpGln: 0.395 ± 0.01	1.038TrpArg: 1.038 ± 0.019	0.907TrpSer: 0.907 ± 0.016	0.795TrpThr: 0.795 ± 0.014	0.945TrpVal: 0.945 ± 0.017	0.308TrpTrp: 0.308 ± 0.01	0.374TrpTyr: 0.374 ± 0.01	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.825TyrAla: 1.825 ± 0.022	0.426TyrCys: 0.426 ± 0.011	1.514TyrAsp: 1.514 ± 0.024	1.481TyrGlu: 1.481 ± 0.02	1.047TyrPhe: 1.047 ± 0.019	1.881TyrGly: 1.881 ± 0.027	0.847TyrHis: 0.847 ± 0.017	1.34TyrIle: 1.34 ± 0.02	1.075TyrLys: 1.075 ± 0.019	2.401TyrLeu: 2.401 ± 0.03	0.551TyrMet: 0.551 ± 0.012	1.053TyrAsn: 1.053 ± 0.017	1.534TyrPro: 1.534 ± 0.022	1.041TyrGln: 1.041 ± 0.017	1.632TyrArg: 1.632 ± 0.021	1.898TyrSer: 1.898 ± 0.025	1.63TyrThr: 1.63 ± 0.021	1.468TyrVal: 1.468 ± 0.02	0.366TyrTrp: 0.366 ± 0.011	0.884TyrTyr: 0.884 ± 0.019	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.023XaaXaa: 0.023 ± 0.013

Statistics based on 9617 proteins (4033769 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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