Amino acid dipepetide frequency for Saitoella complicata (strain BCRC 22490 / CBS 7301 / JCM 7358 / NBRC 10748 / NRRL Y-17804)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	9.526AlaAla: 9.526 ± 0.092	1.062AlaCys: 1.062 ± 0.019	4.038AlaAsp: 4.038 ± 0.039	5.659AlaGlu: 5.659 ± 0.059	3.104AlaPhe: 3.104 ± 0.033	5.905AlaGly: 5.905 ± 0.043	1.897AlaHis: 1.897 ± 0.023	3.936AlaIle: 3.936 ± 0.037	4.476AlaLys: 4.476 ± 0.046	7.854AlaLeu: 7.854 ± 0.047	2.114AlaMet: 2.114 ± 0.024	2.692AlaAsn: 2.692 ± 0.03	5.251AlaPro: 5.251 ± 0.056	3.408AlaGln: 3.408 ± 0.04	5.16AlaArg: 5.16 ± 0.04	7.004AlaSer: 7.004 ± 0.054	5.207AlaThr: 5.207 ± 0.048	5.789AlaVal: 5.789 ± 0.046	1.077AlaTrp: 1.077 ± 0.019	2.243AlaTyr: 2.243 ± 0.027	0.0AlaXaa: 0.0 ± 0.0
Cys	1.012CysAla: 1.012 ± 0.02	0.256CysCys: 0.256 ± 0.01	0.616CysAsp: 0.616 ± 0.013	0.692CysGlu: 0.692 ± 0.015	0.532CysPhe: 0.532 ± 0.015	0.973CysGly: 0.973 ± 0.021	0.315CysHis: 0.315 ± 0.01	0.636CysIle: 0.636 ± 0.014	0.518CysLys: 0.518 ± 0.013	1.268CysLeu: 1.268 ± 0.022	0.295CysMet: 0.295 ± 0.01	0.399CysAsn: 0.399 ± 0.011	0.68CysPro: 0.68 ± 0.015	0.413CysGln: 0.413 ± 0.011	0.798CysArg: 0.798 ± 0.017	0.952CysSer: 0.952 ± 0.019	0.8CysThr: 0.8 ± 0.019	0.95CysVal: 0.95 ± 0.015	0.207CysTrp: 0.207 ± 0.007	0.358CysTyr: 0.358 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	4.71AspAla: 4.71 ± 0.044	0.593AspCys: 0.593 ± 0.013	3.824AspAsp: 3.824 ± 0.053	4.826AspGlu: 4.826 ± 0.045	1.97AspPhe: 1.97 ± 0.027	3.766AspGly: 3.766 ± 0.034	1.115AspHis: 1.115 ± 0.018	2.712AspIle: 2.712 ± 0.028	2.303AspLys: 2.303 ± 0.032	4.803AspLeu: 4.803 ± 0.035	1.311AspMet: 1.311 ± 0.021	1.603AspAsn: 1.603 ± 0.025	2.954AspPro: 2.954 ± 0.026	1.574AspGln: 1.574 ± 0.02	2.805AspArg: 2.805 ± 0.032	3.28AspSer: 3.28 ± 0.036	2.733AspThr: 2.733 ± 0.028	4.08AspVal: 4.08 ± 0.035	0.71AspTrp: 0.71 ± 0.013	1.442AspTyr: 1.442 ± 0.021	0.0AspXaa: 0.0 ± 0.0
Glu	5.69GluAla: 5.69 ± 0.064	0.71GluCys: 0.71 ± 0.016	4.538GluAsp: 4.538 ± 0.047	7.273GluGlu: 7.273 ± 0.067	1.991GluPhe: 1.991 ± 0.025	5.054GluGly: 5.054 ± 0.041	1.45GluHis: 1.45 ± 0.02	2.905GluIle: 2.905 ± 0.032	4.188GluLys: 4.188 ± 0.047	5.356GluLeu: 5.356 ± 0.049	1.72GluMet: 1.72 ± 0.02	2.15GluAsn: 2.15 ± 0.022	2.532GluPro: 2.532 ± 0.032	2.484GluGln: 2.484 ± 0.033	4.582GluArg: 4.582 ± 0.049	4.049GluSer: 4.049 ± 0.034	3.343GluThr: 3.343 ± 0.037	4.617GluVal: 4.617 ± 0.042	0.96GluTrp: 0.96 ± 0.015	1.696GluTyr: 1.696 ± 0.024	0.0GluXaa: 0.0 ± 0.0
Phe	3.101PheAla: 3.101 ± 0.029	0.534PheCys: 0.534 ± 0.012	2.05PheAsp: 2.05 ± 0.026	2.161PheGlu: 2.161 ± 0.027	1.568PhePhe: 1.568 ± 0.027	2.859PheGly: 2.859 ± 0.042	0.813PheHis: 0.813 ± 0.015	1.638PheIle: 1.638 ± 0.026	1.435PheLys: 1.435 ± 0.021	3.348PheLeu: 3.348 ± 0.037	0.779PheMet: 0.779 ± 0.014	1.24PheAsn: 1.24 ± 0.017	1.773PhePro: 1.773 ± 0.023	1.102PheGln: 1.102 ± 0.019	1.918PheArg: 1.918 ± 0.021	2.728PheSer: 2.728 ± 0.028	2.189PheThr: 2.189 ± 0.026	2.483PheVal: 2.483 ± 0.026	0.568PheTrp: 0.568 ± 0.014	1.005PheTyr: 1.005 ± 0.018	0.0PheXaa: 0.0 ± 0.0
Gly	5.49GlyAla: 5.49 ± 0.047	0.928GlyCys: 0.928 ± 0.019	3.534GlyAsp: 3.534 ± 0.031	4.506GlyGlu: 4.506 ± 0.039	2.61GlyPhe: 2.61 ± 0.03	6.381GlyGly: 6.381 ± 0.077	1.668GlyHis: 1.668 ± 0.025	3.183GlyIle: 3.183 ± 0.035	3.718GlyLys: 3.718 ± 0.039	5.921GlyLeu: 5.921 ± 0.046	1.957GlyMet: 1.957 ± 0.032	2.262GlyAsn: 2.262 ± 0.026	2.945GlyPro: 2.945 ± 0.036	2.428GlyGln: 2.428 ± 0.033	4.533GlyArg: 4.533 ± 0.045	5.358GlySer: 5.358 ± 0.051	3.909GlyThr: 3.909 ± 0.041	5.249GlyVal: 5.249 ± 0.042	1.221GlyTrp: 1.221 ± 0.021	2.101GlyTyr: 2.101 ± 0.028	0.0GlyXaa: 0.0 ± 0.0
His	1.981HisAla: 1.981 ± 0.023	0.331HisCys: 0.331 ± 0.01	1.23HisAsp: 1.23 ± 0.02	1.362HisGlu: 1.362 ± 0.019	0.878HisPhe: 0.878 ± 0.015	1.65HisGly: 1.65 ± 0.023	0.893HisHis: 0.893 ± 0.02	1.193HisIle: 1.193 ± 0.02	0.927HisLys: 0.927 ± 0.017	2.345HisLeu: 2.345 ± 0.023	0.475HisMet: 0.475 ± 0.013	0.777HisAsn: 0.777 ± 0.014	1.823HisPro: 1.823 ± 0.027	0.958HisGln: 0.958 ± 0.02	1.495HisArg: 1.495 ± 0.022	1.779HisSer: 1.779 ± 0.027	1.528HisThr: 1.528 ± 0.023	1.576HisVal: 1.576 ± 0.018	0.294HisTrp: 0.294 ± 0.009	0.643HisTyr: 0.643 ± 0.013	0.0HisXaa: 0.0 ± 0.0
Ile	4.131IleAla: 4.131 ± 0.037	0.714IleCys: 0.714 ± 0.016	2.587IleAsp: 2.587 ± 0.028	2.777IleGlu: 2.777 ± 0.026	1.724IlePhe: 1.724 ± 0.023	2.934IleGly: 2.934 ± 0.034	1.198IleHis: 1.198 ± 0.021	2.27IleIle: 2.27 ± 0.028	2.132IleLys: 2.132 ± 0.026	4.258IleLeu: 4.258 ± 0.038	1.028IleMet: 1.028 ± 0.017	1.579IleAsn: 1.579 ± 0.022	3.004IlePro: 3.004 ± 0.029	1.696IleGln: 1.696 ± 0.022	2.789IleArg: 2.789 ± 0.027	3.484IleSer: 3.484 ± 0.035	2.948IleThr: 2.948 ± 0.031	3.029IleVal: 3.029 ± 0.033	0.613IleTrp: 0.613 ± 0.013	1.302IleTyr: 1.302 ± 0.02	0.0IleXaa: 0.0 ± 0.0
Lys	4.529LysAla: 4.529 ± 0.051	0.528LysCys: 0.528 ± 0.015	2.744LysAsp: 2.744 ± 0.03	4.05LysGlu: 4.05 ± 0.041	1.449LysPhe: 1.449 ± 0.019	3.222LysGly: 3.222 ± 0.033	1.181LysHis: 1.181 ± 0.02	2.296LysIle: 2.296 ± 0.027	3.933LysLys: 3.933 ± 0.057	4.042LysLeu: 4.042 ± 0.039	1.162LysMet: 1.162 ± 0.018	1.655LysAsn: 1.655 ± 0.023	2.716LysPro: 2.716 ± 0.035	1.763LysGln: 1.763 ± 0.025	3.595LysArg: 3.595 ± 0.032	3.338LysSer: 3.338 ± 0.034	2.964LysThr: 2.964 ± 0.035	3.234LysVal: 3.234 ± 0.029	0.653LysTrp: 0.653 ± 0.013	1.343LysTyr: 1.343 ± 0.02	0.0LysXaa: 0.0 ± 0.0
Leu	7.592LeuAla: 7.592 ± 0.056	1.234LeuCys: 1.234 ± 0.021	4.777LeuAsp: 4.777 ± 0.046	5.567LeuGlu: 5.567 ± 0.048	3.176LeuPhe: 3.176 ± 0.036	5.952LeuGly: 5.952 ± 0.047	2.36LeuHis: 2.36 ± 0.026	3.804LeuIle: 3.804 ± 0.038	4.318LeuLys: 4.318 ± 0.038	8.523LeuLeu: 8.523 ± 0.077	1.746LeuMet: 1.746 ± 0.024	3.029LeuAsn: 3.029 ± 0.03	5.608LeuPro: 5.608 ± 0.05	3.564LeuGln: 3.564 ± 0.036	6.142LeuArg: 6.142 ± 0.055	7.198LeuSer: 7.198 ± 0.054	5.198LeuThr: 5.198 ± 0.039	5.384LeuVal: 5.384 ± 0.043	1.072LeuTrp: 1.072 ± 0.02	2.253LeuTyr: 2.253 ± 0.029	0.0LeuXaa: 0.0 ± 0.0
Met	1.953MetAla: 1.953 ± 0.024	0.297MetCys: 0.297 ± 0.009	1.311MetAsp: 1.311 ± 0.018	1.519MetGlu: 1.519 ± 0.021	0.785MetPhe: 0.785 ± 0.015	1.693MetGly: 1.693 ± 0.023	0.505MetHis: 0.505 ± 0.012	0.996MetIle: 0.996 ± 0.016	1.181MetLys: 1.181 ± 0.018	1.897MetLeu: 1.897 ± 0.024	0.634MetMet: 0.634 ± 0.014	0.869MetAsn: 0.869 ± 0.016	1.349MetPro: 1.349 ± 0.021	0.883MetGln: 0.883 ± 0.015	1.416MetArg: 1.416 ± 0.02	2.142MetSer: 2.142 ± 0.025	1.371MetThr: 1.371 ± 0.019	1.404MetVal: 1.404 ± 0.019	0.28MetTrp: 0.28 ± 0.01	0.549MetTyr: 0.549 ± 0.011	0.0MetXaa: 0.0 ± 0.0
Asn	3.018AsnAla: 3.018 ± 0.032	0.426AsnCys: 0.426 ± 0.013	1.731AsnAsp: 1.731 ± 0.023	1.915AsnGlu: 1.915 ± 0.025	1.146AsnPhe: 1.146 ± 0.017	2.602AsnGly: 2.602 ± 0.028	0.78AsnHis: 0.78 ± 0.017	1.756AsnIle: 1.756 ± 0.025	1.491AsnLys: 1.491 ± 0.023	3.03AsnLeu: 3.03 ± 0.028	0.816AsnMet: 0.816 ± 0.017	1.206AsnAsn: 1.206 ± 0.025	2.266AsnPro: 2.266 ± 0.027	1.109AsnGln: 1.109 ± 0.016	1.737AsnArg: 1.737 ± 0.024	2.25AsnSer: 2.25 ± 0.03	2.121AsnThr: 2.121 ± 0.029	2.371AsnVal: 2.371 ± 0.026	0.459AsnTrp: 0.459 ± 0.012	0.902AsnTyr: 0.902 ± 0.017	0.0AsnXaa: 0.0 ± 0.0
Pro	5.537ProAla: 5.537 ± 0.052	0.546ProCys: 0.546 ± 0.014	2.679ProAsp: 2.679 ± 0.028	3.592ProGlu: 3.592 ± 0.035	2.002ProPhe: 2.002 ± 0.024	3.578ProGly: 3.578 ± 0.043	1.427ProHis: 1.427 ± 0.02	2.504ProIle: 2.504 ± 0.03	2.671ProLys: 2.671 ± 0.032	4.735ProLeu: 4.735 ± 0.043	1.166ProMet: 1.166 ± 0.02	1.974ProAsn: 1.974 ± 0.023	5.423ProPro: 5.423 ± 0.087	2.311ProGln: 2.311 ± 0.035	3.541ProArg: 3.541 ± 0.044	5.916ProSer: 5.916 ± 0.051	4.525ProThr: 4.525 ± 0.045	3.942ProVal: 3.942 ± 0.041	0.624ProTrp: 0.624 ± 0.015	1.462ProTyr: 1.462 ± 0.02	0.0ProXaa: 0.0 ± 0.0
Gln	3.168GlnAla: 3.168 ± 0.038	0.405GlnCys: 0.405 ± 0.009	1.701GlnAsp: 1.701 ± 0.024	2.275GlnGlu: 2.275 ± 0.03	1.179GlnPhe: 1.179 ± 0.018	2.291GlnGly: 2.291 ± 0.031	1.137GlnHis: 1.137 ± 0.02	1.72GlnIle: 1.72 ± 0.025	1.948GlnLys: 1.948 ± 0.028	3.272GlnLeu: 3.272 ± 0.034	0.866GlnMet: 0.866 ± 0.017	1.304GlnAsn: 1.304 ± 0.022	2.309GlnPro: 2.309 ± 0.036	2.501GlnGln: 2.501 ± 0.069	2.524GlnArg: 2.524 ± 0.029	2.781GlnSer: 2.781 ± 0.032	2.239GlnThr: 2.239 ± 0.028	2.168GlnVal: 2.168 ± 0.029	0.469GlnTrp: 0.469 ± 0.011	1.031GlnTyr: 1.031 ± 0.019	0.0GlnXaa: 0.0 ± 0.0
Arg	5.004ArgAla: 5.004 ± 0.044	0.815ArgCys: 0.815 ± 0.014	3.207ArgAsp: 3.207 ± 0.036	4.385ArgGlu: 4.385 ± 0.049	2.056ArgPhe: 2.056 ± 0.025	4.109ArgGly: 4.109 ± 0.042	1.509ArgHis: 1.509 ± 0.023	2.949ArgIle: 2.949 ± 0.03	3.612ArgLys: 3.612 ± 0.034	5.428ArgLeu: 5.428 ± 0.042	1.466ArgMet: 1.466 ± 0.021	2.098ArgAsn: 2.098 ± 0.025	3.501ArgPro: 3.501 ± 0.039	2.426ArgGln: 2.426 ± 0.03	5.574ArgArg: 5.574 ± 0.056	4.901ArgSer: 4.901 ± 0.05	3.802ArgThr: 3.802 ± 0.036	3.951ArgVal: 3.951 ± 0.036	0.898ArgTrp: 0.898 ± 0.018	1.664ArgTyr: 1.664 ± 0.022	0.0ArgXaa: 0.0 ± 0.0
Ser	6.882SerAla: 6.882 ± 0.064	0.906SerCys: 0.906 ± 0.02	3.629SerAsp: 3.629 ± 0.03	3.949SerGlu: 3.949 ± 0.036	2.869SerPhe: 2.869 ± 0.031	5.208SerGly: 5.208 ± 0.044	1.846SerHis: 1.846 ± 0.028	3.752SerIle: 3.752 ± 0.033	3.388SerLys: 3.388 ± 0.038	7.065SerLeu: 7.065 ± 0.052	1.653SerMet: 1.653 ± 0.023	2.513SerAsn: 2.513 ± 0.027	5.426SerPro: 5.426 ± 0.062	2.674SerGln: 2.674 ± 0.03	4.729SerArg: 4.729 ± 0.052	8.649SerSer: 8.649 ± 0.09	6.066SerThr: 6.066 ± 0.058	4.797SerVal: 4.797 ± 0.04	0.923SerTrp: 0.923 ± 0.018	2.032SerTyr: 2.032 ± 0.028	0.0SerXaa: 0.0 ± 0.0
Thr	5.446ThrAla: 5.446 ± 0.042	0.78ThrCys: 0.78 ± 0.017	2.705ThrAsp: 2.705 ± 0.027	3.305ThrGlu: 3.305 ± 0.037	2.246ThrPhe: 2.246 ± 0.023	4.14ThrGly: 4.14 ± 0.043	1.529ThrHis: 1.529 ± 0.022	2.988ThrIle: 2.988 ± 0.028	2.808ThrLys: 2.808 ± 0.034	5.578ThrLeu: 5.578 ± 0.043	1.326ThrMet: 1.326 ± 0.02	2.02ThrAsn: 2.02 ± 0.024	5.008ThrPro: 5.008 ± 0.05	2.059ThrGln: 2.059 ± 0.024	3.382ThrArg: 3.382 ± 0.032	5.712ThrSer: 5.712 ± 0.053	4.967ThrThr: 4.967 ± 0.07	3.833ThrVal: 3.833 ± 0.04	0.762ThrTrp: 0.762 ± 0.015	1.687ThrTyr: 1.687 ± 0.023	0.0ThrXaa: 0.0 ± 0.0
Val	5.402ValAla: 5.402 ± 0.048	0.978ValCys: 0.978 ± 0.019	3.8ValAsp: 3.8 ± 0.037	4.961ValGlu: 4.961 ± 0.041	2.431ValPhe: 2.431 ± 0.027	4.691ValGly: 4.691 ± 0.041	1.508ValHis: 1.508 ± 0.021	2.964ValIle: 2.964 ± 0.03	3.47ValLys: 3.47 ± 0.041	6.02ValLeu: 6.02 ± 0.046	1.576ValMet: 1.576 ± 0.022	2.262ValAsn: 2.262 ± 0.024	3.698ValPro: 3.698 ± 0.035	2.52ValGln: 2.52 ± 0.026	4.148ValArg: 4.148 ± 0.035	4.627ValSer: 4.627 ± 0.041	3.785ValThr: 3.785 ± 0.041	5.21ValVal: 5.21 ± 0.055	0.97ValTrp: 0.97 ± 0.018	1.792ValTyr: 1.792 ± 0.023	0.0ValXaa: 0.0 ± 0.0
Trp	0.976TrpAla: 0.976 ± 0.017	0.224TrpCys: 0.224 ± 0.008	0.814TrpAsp: 0.814 ± 0.015	0.874TrpGlu: 0.874 ± 0.016	0.487TrpPhe: 0.487 ± 0.013	0.896TrpGly: 0.896 ± 0.015	0.295TrpHis: 0.295 ± 0.009	0.673TrpIle: 0.673 ± 0.014	0.762TrpLys: 0.762 ± 0.014	1.139TrpLeu: 1.139 ± 0.021	0.375TrpMet: 0.375 ± 0.01	0.53TrpAsn: 0.53 ± 0.011	0.484TrpPro: 0.484 ± 0.012	0.466TrpGln: 0.466 ± 0.011	0.957TrpArg: 0.957 ± 0.018	1.0TrpSer: 1.0 ± 0.016	0.848TrpThr: 0.848 ± 0.016	0.94TrpVal: 0.94 ± 0.017	0.263TrpTrp: 0.263 ± 0.009	0.383TrpTyr: 0.383 ± 0.01	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.254TyrAla: 2.254 ± 0.028	0.407TyrCys: 0.407 ± 0.012	1.601TyrAsp: 1.601 ± 0.025	1.638TyrGlu: 1.638 ± 0.023	1.087TyrPhe: 1.087 ± 0.018	1.997TyrGly: 1.997 ± 0.027	0.716TyrHis: 0.716 ± 0.014	1.321TyrIle: 1.321 ± 0.021	1.118TyrLys: 1.118 ± 0.02	2.613TyrLeu: 2.613 ± 0.026	0.568TyrMet: 0.568 ± 0.011	0.969TyrAsn: 0.969 ± 0.017	1.403TyrPro: 1.403 ± 0.024	0.949TyrGln: 0.949 ± 0.014	1.534TyrArg: 1.534 ± 0.022	1.807TyrSer: 1.807 ± 0.027	1.736TyrThr: 1.736 ± 0.026	1.806TyrVal: 1.806 ± 0.026	0.362TyrTrp: 0.362 ± 0.011	0.818TyrTyr: 0.818 ± 0.015	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 7118 proteins (3658384 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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