Esox lucius (Northern pike)

Taxonomy: cellular organisms; Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi; Actinopterygii; Actinopteri; Neopterygii; Teleostei; Osteoglossocephalai; Clupeocephala; Euteleosteomorpha; Protacanthopterygii; Esociformes; Esocidae; Esox

Average proteome isoelectric point is 6.47

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 71519 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A6Q2X6C8|A0A6Q2X6C8_ESOLU Multiple C2 and transmembrane domain-containing protein 1 OS=Esox lucius OX=8010 PE=4 SV=1
HHH2 pKa = 7.77LYYY5 pKa = 11.04RR6 pKa = 11.84DDD8 pKa = 3.41KK9 pKa = 10.26QIKKK13 pKa = 7.51KKK15 pKa = 9.87QLGSVRR21 pKa = 11.84CHHH24 pKa = 7.43EEE26 pKa = 3.54DD27 pKa = 4.05DD28 pKa = 3.51CLVDDD33 pKa = 5.31DD34 pKa = 4.66VCFRR38 pKa = 11.84EEE40 pKa = 4.78DD41 pKa = 3.55QCLVDDD47 pKa = 4.72DD48 pKa = 4.45VCFRR52 pKa = 11.84EEE54 pKa = 4.46DD55 pKa = 3.26QSLVDDD61 pKa = 4.34DD62 pKa = 4.79VCFRR66 pKa = 11.84EEE68 pKa = 4.88DD69 pKa = 3.72QCLVDDD75 pKa = 4.72DD76 pKa = 4.45VCFRR80 pKa = 11.84EEE82 pKa = 4.46DD83 pKa = 3.17QSLVDDD89 pKa = 3.49EE90 pKa = 4.91VCFRR94 pKa = 11.84EEE96 pKa = 4.84DD97 pKa = 3.51QSLLDDD103 pKa = 3.55EE104 pKa = 4.59VCFRR108 pKa = 11.84EEE110 pKa = 4.67DD111 pKa = 3.36QSLVDDD117 pKa = 3.49EE118 pKa = 4.91VCFRR122 pKa = 11.84EEE124 pKa = 4.67DD125 pKa = 3.36QSLVDDD131 pKa = 3.49EE132 pKa = 4.91VCFRR136 pKa = 11.84EEE138 pKa = 4.67DD139 pKa = 3.36QSLVDDD145 pKa = 3.49EE146 pKa = 4.91VCFRR150 pKa = 11.84EEE152 pKa = 5.01DD153 pKa = 3.64QCLVDDD159 pKa = 3.71EE160 pKa = 5.03VCFRR164 pKa = 11.84EEE166 pKa = 5.01DD167 pKa = 3.73QCLVDDD173 pKa = 4.95DD174 pKa = 4.92VCFRR178 pKa = 11.84EEE180 pKa = 4.57DD181 pKa = 3.44QSLVDDD187 pKa = 5.05DD188 pKa = 4.6EE189 pKa = 4.78CLRR192 pKa = 11.84EEE194 pKa = 4.48GQCLVDDD201 pKa = 3.38EE202 pKa = 5.04VCFRR206 pKa = 11.84EEE208 pKa = 5.07GQSLVDDD215 pKa = 3.32EE216 pKa = 4.92VCFRR220 pKa = 11.84EEE222 pKa = 4.67DD223 pKa = 3.45QSLVDDD229 pKa = 4.34DD230 pKa = 4.79VCFRR234 pKa = 11.84EEE236 pKa = 4.57DD237 pKa = 3.44QSLVDDD243 pKa = 3.95DD244 pKa = 4.24VCFRR248 pKa = 11.84EEE250 pKa = 4.62GQCLVDDD257 pKa = 3.38EE258 pKa = 5.05VCFRR262 pKa = 11.84EEE264 pKa = 4.67DD265 pKa = 3.45QSLVDDD271 pKa = 4.34DD272 pKa = 4.79VCFRR276 pKa = 11.84EEE278 pKa = 4.88DD279 pKa = 3.72QCLVDDD285 pKa = 4.95DD286 pKa = 4.92VCFRR290 pKa = 11.84EEE292 pKa = 4.88DD293 pKa = 3.72QCLVDDD299 pKa = 4.95DD300 pKa = 4.92VCFRR304 pKa = 11.84EEE306 pKa = 4.88DD307 pKa = 3.72QCLVDDD313 pKa = 4.95DD314 pKa = 4.92VCFRR318 pKa = 11.84EEE320 pKa = 4.88DD321 pKa = 3.72QCLVDDD327 pKa = 4.72DD328 pKa = 4.45VCFRR332 pKa = 11.84EEE334 pKa = 4.78DD335 pKa = 3.55QCLVDDD341 pKa = 4.95DD342 pKa = 4.92VCFRR346 pKa = 11.84EEE348 pKa = 4.88DD349 pKa = 3.61QCLVDDD355 pKa = 3.71EE356 pKa = 5.03VCFRR360 pKa = 11.84EEE362 pKa = 5.01DD363 pKa = 3.64QCLVDDD369 pKa = 3.71EE370 pKa = 5.03VCFRR374 pKa = 11.84EEE376 pKa = 4.67DD377 pKa = 3.36QSLVDDD383 pKa = 3.22EE384 pKa = 4.56VRR386 pKa = 11.84FRR388 pKa = 11.84EEE390 pKa = 4.53DD391 pKa = 3.18QSLVDDD397 pKa = 4.34DD398 pKa = 4.72VCFRR402 pKa = 11.84EEE404 pKa = 4.28EE405 pKa = 4.17QSLVDDD411 pKa = 4.28DD412 pKa = 4.89VCFRR416 pKa = 11.84SRR418 pKa = 11.84QSVSG

Molecular weight: 47.13 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A6Q2ZIK4|A0A6Q2ZIK4_ESOLU NF-kappa-B inhibitor alpha OS=Esox lucius OX=8010 PE=4 SV=1
MM1 pKa = 7.2QGISVPINTPRR12 pKa = 11.84TRR14 pKa = 11.84VPINTPRR21 pKa = 11.84TRR23 pKa = 11.84VPINTPRR30 pKa = 11.84TRR32 pKa = 11.84VPINTPRR39 pKa = 11.84TRR41 pKa = 11.84VPINTPRR48 pKa = 11.84TRR50 pKa = 11.84VPINTPRR57 pKa = 11.84TRR59 pKa = 11.84VPINTPRR66 pKa = 11.84TRR68 pKa = 11.84VPINTPRR75 pKa = 11.84TRR77 pKa = 11.84VPINTPRR84 pKa = 11.84TRR86 pKa = 11.84VPINTPRR93 pKa = 11.84TRR95 pKa = 11.84VPINTPRR102 pKa = 11.84TRR104 pKa = 11.84VPINTPRR111 pKa = 11.84TRR113 pKa = 11.84VPINTPRR120 pKa = 11.84TRR122 pKa = 11.84SGVSAPTPNPGIDD135 pKa = 3.48QSSHH139 pKa = 6.38SII141 pKa = 3.44

Molecular weight: 15.83 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

24811

46708

71519

50391987

18

8678

704.6

78.73

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

6.342 ± 0.007

2.322 ± 0.007

5.233 ± 0.006

6.705 ± 0.011

3.714 ± 0.006

6.555 ± 0.008

2.667 ± 0.004

4.51 ± 0.006

5.495 ± 0.009

9.673 ± 0.01

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.432 ± 0.003

3.903 ± 0.005

5.672 ± 0.01

4.605 ± 0.007

5.625 ± 0.006

8.212 ± 0.009

5.707 ± 0.01

6.555 ± 0.007

1.197 ± 0.003

2.876 ± 0.005
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski