Amino acid dipepetide frequency for Phaseolus angularis (Azuki bean) (Vigna angularis)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.84AlaAla: 5.84 ± 0.034	1.179AlaCys: 1.179 ± 0.01	2.962AlaAsp: 2.962 ± 0.025	4.205AlaGlu: 4.205 ± 0.026	2.682AlaPhe: 2.682 ± 0.015	3.724AlaGly: 3.724 ± 0.021	1.306AlaHis: 1.306 ± 0.012	3.545AlaIle: 3.545 ± 0.018	3.608AlaLys: 3.608 ± 0.021	6.237AlaLeu: 6.237 ± 0.028	1.647AlaMet: 1.647 ± 0.013	2.528AlaAsn: 2.528 ± 0.016	2.864AlaPro: 2.864 ± 0.019	2.122AlaGln: 2.122 ± 0.016	3.477AlaArg: 3.477 ± 0.022	5.862AlaSer: 5.862 ± 0.03	3.634AlaThr: 3.634 ± 0.02	4.626AlaVal: 4.626 ± 0.023	0.787AlaTrp: 0.787 ± 0.008	1.688AlaTyr: 1.688 ± 0.012	0.001AlaXaa: 0.001 ± 0.0
Cys	1.01CysAla: 1.01 ± 0.009	0.521CysCys: 0.521 ± 0.008	0.877CysAsp: 0.877 ± 0.01	0.911CysGlu: 0.911 ± 0.01	0.87CysPhe: 0.87 ± 0.008	1.387CysGly: 1.387 ± 0.011	0.502CysHis: 0.502 ± 0.007	0.933CysIle: 0.933 ± 0.009	1.072CysLys: 1.072 ± 0.011	1.759CysLeu: 1.759 ± 0.014	0.46CysMet: 0.46 ± 0.006	0.827CysAsn: 0.827 ± 0.01	0.905CysPro: 0.905 ± 0.011	0.598CysGln: 0.598 ± 0.007	1.018CysArg: 1.018 ± 0.01	1.827CysSer: 1.827 ± 0.014	0.861CysThr: 0.861 ± 0.008	1.129CysVal: 1.129 ± 0.011	0.289CysTrp: 0.289 ± 0.005	0.54CysTyr: 0.54 ± 0.006	0.0CysXaa: 0.0 ± 0.0
Asp	3.421AspAla: 3.421 ± 0.019	0.903AspCys: 0.903 ± 0.009	3.954AspAsp: 3.954 ± 0.031	7.45AspGlu: 7.45 ± 0.344	2.247AspPhe: 2.247 ± 0.016	3.646AspGly: 3.646 ± 0.021	1.203AspHis: 1.203 ± 0.012	2.86AspIle: 2.86 ± 0.016	2.831AspLys: 2.831 ± 0.026	4.847AspLeu: 4.847 ± 0.033	1.304AspMet: 1.304 ± 0.011	2.058AspAsn: 2.058 ± 0.016	2.504AspPro: 2.504 ± 0.017	1.655AspGln: 1.655 ± 0.012	2.309AspArg: 2.309 ± 0.014	4.104AspSer: 4.104 ± 0.022	2.261AspThr: 2.261 ± 0.016	3.852AspVal: 3.852 ± 0.029	0.701AspTrp: 0.701 ± 0.007	1.47AspTyr: 1.47 ± 0.012	0.0AspXaa: 0.0 ± 0.0
Glu	4.736GluAla: 4.736 ± 0.03	0.955GluCys: 0.955 ± 0.01	4.409GluAsp: 4.409 ± 0.073	8.702GluGlu: 8.702 ± 0.212	2.33GluPhe: 2.33 ± 0.012	4.316GluGly: 4.316 ± 0.067	1.319GluHis: 1.319 ± 0.011	3.645GluIle: 3.645 ± 0.021	4.802GluLys: 4.802 ± 0.033	5.86GluLeu: 5.86 ± 0.043	1.978GluMet: 1.978 ± 0.041	3.064GluAsn: 3.064 ± 0.02	2.09GluPro: 2.09 ± 0.016	2.271GluGln: 2.271 ± 0.016	3.775GluArg: 3.775 ± 0.026	4.384GluSer: 4.384 ± 0.023	2.895GluThr: 2.895 ± 0.02	8.17GluVal: 8.17 ± 0.406	0.758GluTrp: 0.758 ± 0.008	1.575GluTyr: 1.575 ± 0.014	0.001GluXaa: 0.001 ± 0.0
Phe	2.372PheAla: 2.372 ± 0.015	0.893PheCys: 0.893 ± 0.009	2.297PheAsp: 2.297 ± 0.015	2.299PheGlu: 2.299 ± 0.015	1.954PhePhe: 1.954 ± 0.015	3.081PheGly: 3.081 ± 0.019	1.17PheHis: 1.17 ± 0.01	2.041PheIle: 2.041 ± 0.015	2.067PheLys: 2.067 ± 0.015	4.204PheLeu: 4.204 ± 0.023	0.958PheMet: 0.958 ± 0.009	1.805PheAsn: 1.805 ± 0.014	2.064PhePro: 2.064 ± 0.015	1.599PheGln: 1.599 ± 0.011	2.034PheArg: 2.034 ± 0.014	4.038PheSer: 4.038 ± 0.023	1.963PheThr: 1.963 ± 0.014	2.802PheVal: 2.802 ± 0.028	0.543PheTrp: 0.543 ± 0.008	1.291PheTyr: 1.291 ± 0.01	0.0PheXaa: 0.0 ± 0.0
Gly	3.738GlyAla: 3.738 ± 0.023	1.276GlyCys: 1.276 ± 0.013	3.556GlyAsp: 3.556 ± 0.063	4.056GlyGlu: 4.056 ± 0.036	3.031GlyPhe: 3.031 ± 0.019	5.455GlyGly: 5.455 ± 0.061	1.598GlyHis: 1.598 ± 0.014	3.296GlyIle: 3.296 ± 0.019	3.99GlyLys: 3.99 ± 0.021	5.556GlyLeu: 5.556 ± 0.026	1.444GlyMet: 1.444 ± 0.012	3.03GlyAsn: 3.03 ± 0.021	2.278GlyPro: 2.278 ± 0.017	2.035GlyGln: 2.035 ± 0.014	3.83GlyArg: 3.83 ± 0.025	5.667GlySer: 5.667 ± 0.03	3.122GlyThr: 3.122 ± 0.02	4.438GlyVal: 4.438 ± 0.021	0.923GlyTrp: 0.923 ± 0.01	1.971GlyTyr: 1.971 ± 0.013	0.001GlyXaa: 0.001 ± 0.0
His	1.533HisAla: 1.533 ± 0.011	0.538HisCys: 0.538 ± 0.008	1.201HisAsp: 1.201 ± 0.012	1.494HisGlu: 1.494 ± 0.02	1.189HisPhe: 1.189 ± 0.023	1.705HisGly: 1.705 ± 0.012	1.044HisHis: 1.044 ± 0.013	1.189HisIle: 1.189 ± 0.011	1.196HisLys: 1.196 ± 0.009	2.443HisLeu: 2.443 ± 0.016	0.572HisMet: 0.572 ± 0.007	1.022HisAsn: 1.022 ± 0.011	1.502HisPro: 1.502 ± 0.013	1.034HisGln: 1.034 ± 0.01	1.469HisArg: 1.469 ± 0.014	2.104HisSer: 2.104 ± 0.013	1.053HisThr: 1.053 ± 0.009	1.694HisVal: 1.694 ± 0.011	0.312HisTrp: 0.312 ± 0.005	0.723HisTyr: 0.723 ± 0.009	0.0HisXaa: 0.0 ± 0.0
Ile	3.36IleAla: 3.36 ± 0.019	1.009IleCys: 1.009 ± 0.011	2.823IleAsp: 2.823 ± 0.017	3.064IleGlu: 3.064 ± 0.02	2.122IlePhe: 2.122 ± 0.014	3.322IleGly: 3.322 ± 0.024	1.362IleHis: 1.362 ± 0.013	2.698IleIle: 2.698 ± 0.017	2.75IleLys: 2.75 ± 0.015	4.856IleLeu: 4.856 ± 0.024	1.119IleMet: 1.119 ± 0.012	2.122IleAsn: 2.122 ± 0.013	2.91IlePro: 2.91 ± 0.02	1.953IleGln: 1.953 ± 0.016	2.648IleArg: 2.648 ± 0.018	4.472IleSer: 4.472 ± 0.02	2.61IleThr: 2.61 ± 0.015	3.433IleVal: 3.433 ± 0.038	0.676IleTrp: 0.676 ± 0.008	1.381IleTyr: 1.381 ± 0.011	0.0IleXaa: 0.0 ± 0.0
Lys	3.774LysAla: 3.774 ± 0.021	0.951LysCys: 0.951 ± 0.009	3.077LysAsp: 3.077 ± 0.019	4.728LysGlu: 4.728 ± 0.034	2.078LysPhe: 2.078 ± 0.013	3.703LysGly: 3.703 ± 0.022	1.412LysHis: 1.412 ± 0.012	3.096LysIle: 3.096 ± 0.018	4.633LysLys: 4.633 ± 0.035	5.598LysLeu: 5.598 ± 0.025	1.474LysMet: 1.474 ± 0.013	2.632LysAsn: 2.632 ± 0.019	2.555LysPro: 2.555 ± 0.02	2.108LysGln: 2.108 ± 0.015	3.627LysArg: 3.627 ± 0.019	4.343LysSer: 4.343 ± 0.026	2.829LysThr: 2.829 ± 0.018	4.161LysVal: 4.161 ± 0.032	0.886LysTrp: 0.886 ± 0.015	1.505LysTyr: 1.505 ± 0.012	0.001LysXaa: 0.001 ± 0.0
Leu	6.054LeuAla: 6.054 ± 0.027	1.894LeuCys: 1.894 ± 0.013	4.999LeuAsp: 4.999 ± 0.04	6.021LeuGlu: 6.021 ± 0.03	3.754LeuPhe: 3.754 ± 0.021	5.575LeuGly: 5.575 ± 0.025	2.681LeuHis: 2.681 ± 0.018	4.374LeuIle: 4.374 ± 0.048	5.792LeuLys: 5.792 ± 0.029	9.456LeuLeu: 9.456 ± 0.038	2.024LeuMet: 2.024 ± 0.015	3.954LeuAsn: 3.954 ± 0.022	5.028LeuPro: 5.028 ± 0.029	4.095LeuGln: 4.095 ± 0.022	5.379LeuArg: 5.379 ± 0.033	8.421LeuSer: 8.421 ± 0.041	4.419LeuThr: 4.419 ± 0.022	6.185LeuVal: 6.185 ± 0.028	1.098LeuTrp: 1.098 ± 0.01	2.388LeuTyr: 2.388 ± 0.014	0.002LeuXaa: 0.002 ± 0.0
Met	1.999MetAla: 1.999 ± 0.014	0.338MetCys: 0.338 ± 0.006	1.572MetAsp: 1.572 ± 0.037	2.086MetGlu: 2.086 ± 0.014	0.796MetPhe: 0.796 ± 0.007	1.523MetGly: 1.523 ± 0.013	0.529MetHis: 0.529 ± 0.006	1.18MetIle: 1.18 ± 0.011	1.659MetLys: 1.659 ± 0.012	2.063MetLeu: 2.063 ± 0.015	0.691MetMet: 0.691 ± 0.008	1.025MetAsn: 1.025 ± 0.01	0.964MetPro: 0.964 ± 0.01	0.903MetGln: 0.903 ± 0.01	1.182MetArg: 1.182 ± 0.011	1.752MetSer: 1.752 ± 0.015	1.095MetThr: 1.095 ± 0.009	1.63MetVal: 1.63 ± 0.012	0.263MetTrp: 0.263 ± 0.005	0.62MetTyr: 0.62 ± 0.009	0.0MetXaa: 0.0 ± 0.0
Asn	2.646AsnAla: 2.646 ± 0.015	0.828AsnCys: 0.828 ± 0.01	2.135AsnAsp: 2.135 ± 0.018	2.647AsnGlu: 2.647 ± 0.019	1.969AsnPhe: 1.969 ± 0.017	3.092AsnGly: 3.092 ± 0.021	1.174AsnHis: 1.174 ± 0.012	2.613AsnIle: 2.613 ± 0.017	2.401AsnLys: 2.401 ± 0.019	4.497AsnLeu: 4.497 ± 0.029	1.116AsnMet: 1.116 ± 0.01	2.409AsnAsn: 2.409 ± 0.029	2.223AsnPro: 2.223 ± 0.015	1.61AsnGln: 1.61 ± 0.012	2.086AsnArg: 2.086 ± 0.017	3.816AsnSer: 3.816 ± 0.024	2.062AsnThr: 2.062 ± 0.015	2.959AsnVal: 2.959 ± 0.015	0.594AsnTrp: 0.594 ± 0.008	1.264AsnTyr: 1.264 ± 0.012	0.0AsnXaa: 0.0 ± 0.0
Pro	2.85ProAla: 2.85 ± 0.023	0.787ProCys: 0.787 ± 0.008	2.324ProAsp: 2.324 ± 0.015	2.862ProGlu: 2.862 ± 0.016	2.194ProPhe: 2.194 ± 0.017	2.451ProGly: 2.451 ± 0.017	1.256ProHis: 1.256 ± 0.011	2.19ProIle: 2.19 ± 0.015	2.617ProLys: 2.617 ± 0.019	4.588ProLeu: 4.588 ± 0.033	0.917ProMet: 0.917 ± 0.011	2.344ProAsn: 2.344 ± 0.015	4.334ProPro: 4.334 ± 0.066	1.9ProGln: 1.9 ± 0.016	2.494ProArg: 2.494 ± 0.018	5.413ProSer: 5.413 ± 0.031	2.837ProThr: 2.837 ± 0.021	2.92ProVal: 2.92 ± 0.02	0.594ProTrp: 0.594 ± 0.007	1.319ProTyr: 1.319 ± 0.014	0.001ProXaa: 0.001 ± 0.0
Gln	2.238GlnAla: 2.238 ± 0.015	0.629GlnCys: 0.629 ± 0.007	1.612GlnAsp: 1.612 ± 0.013	2.325GlnGlu: 2.325 ± 0.016	1.448GlnPhe: 1.448 ± 0.013	2.036GlnGly: 2.036 ± 0.014	0.984GlnHis: 0.984 ± 0.012	1.919GlnIle: 1.919 ± 0.014	2.223GlnLys: 2.223 ± 0.018	3.541GlnLeu: 3.541 ± 0.024	0.988GlnMet: 0.988 ± 0.01	1.805GlnAsn: 1.805 ± 0.012	1.965GlnPro: 1.965 ± 0.017	2.083GlnGln: 2.083 ± 0.025	2.201GlnArg: 2.201 ± 0.014	2.745GlnSer: 2.745 ± 0.019	1.8GlnThr: 1.8 ± 0.014	2.366GlnVal: 2.366 ± 0.017	0.468GlnTrp: 0.468 ± 0.006	0.897GlnTyr: 0.897 ± 0.009	0.0GlnXaa: 0.0 ± 0.0
Arg	3.245ArgAla: 3.245 ± 0.018	0.961ArgCys: 0.961 ± 0.009	2.623ArgAsp: 2.623 ± 0.017	3.392ArgGlu: 3.392 ± 0.02	2.193ArgPhe: 2.193 ± 0.013	3.38ArgGly: 3.38 ± 0.021	1.364ArgHis: 1.364 ± 0.01	2.711ArgIle: 2.711 ± 0.016	3.873ArgLys: 3.873 ± 0.025	4.859ArgLeu: 4.859 ± 0.023	1.333ArgMet: 1.333 ± 0.011	2.488ArgAsn: 2.488 ± 0.017	2.688ArgPro: 2.688 ± 0.028	1.936ArgGln: 1.936 ± 0.015	4.198ArgArg: 4.198 ± 0.032	4.511ArgSer: 4.511 ± 0.026	2.697ArgThr: 2.697 ± 0.018	3.513ArgVal: 3.513 ± 0.018	0.82ArgTrp: 0.82 ± 0.011	1.4ArgTyr: 1.4 ± 0.012	0.001ArgXaa: 0.001 ± 0.0
Ser	5.133SerAla: 5.133 ± 0.027	1.641SerCys: 1.641 ± 0.014	4.296SerAsp: 4.296 ± 0.023	4.754SerGlu: 4.754 ± 0.025	3.93SerPhe: 3.93 ± 0.02	5.72SerGly: 5.72 ± 0.028	2.166SerHis: 2.166 ± 0.015	4.289SerIle: 4.289 ± 0.022	4.666SerLys: 4.666 ± 0.024	8.466SerLeu: 8.466 ± 0.036	2.007SerMet: 2.007 ± 0.013	4.05SerAsn: 4.05 ± 0.026	4.52SerPro: 4.52 ± 0.042	2.962SerGln: 2.962 ± 0.018	4.434SerArg: 4.434 ± 0.024	10.859SerSer: 10.859 ± 0.058	4.771SerThr: 4.771 ± 0.029	5.346SerVal: 5.346 ± 0.028	1.153SerTrp: 1.153 ± 0.011	2.223SerTyr: 2.223 ± 0.014	0.001SerXaa: 0.001 ± 0.0
Thr	3.271ThrAla: 3.271 ± 0.02	0.903ThrCys: 0.903 ± 0.01	2.198ThrAsp: 2.198 ± 0.013	2.781ThrGlu: 2.781 ± 0.018	2.13ThrPhe: 2.13 ± 0.014	3.036ThrGly: 3.036 ± 0.018	1.225ThrHis: 1.225 ± 0.011	2.696ThrIle: 2.696 ± 0.016	2.747ThrLys: 2.747 ± 0.021	4.824ThrLeu: 4.824 ± 0.024	1.216ThrMet: 1.216 ± 0.01	2.234ThrAsn: 2.234 ± 0.014	2.783ThrPro: 2.783 ± 0.023	1.656ThrGln: 1.656 ± 0.014	2.461ThrArg: 2.461 ± 0.014	4.6ThrSer: 4.6 ± 0.027	3.133ThrThr: 3.133 ± 0.019	3.468ThrVal: 3.468 ± 0.017	0.644ThrTrp: 0.644 ± 0.008	1.327ThrTyr: 1.327 ± 0.012	0.0ThrXaa: 0.0 ± 0.0
Val	4.862ValAla: 4.862 ± 0.024	1.173ValCys: 1.173 ± 0.01	6.504ValAsp: 6.504 ± 0.293	5.978ValGlu: 5.978 ± 0.148	2.758ValPhe: 2.758 ± 0.017	4.384ValGly: 4.384 ± 0.037	1.763ValHis: 1.763 ± 0.024	3.347ValIle: 3.347 ± 0.02	3.873ValLys: 3.873 ± 0.02	6.137ValLeu: 6.137 ± 0.027	1.492ValMet: 1.492 ± 0.011	2.789ValAsn: 2.789 ± 0.019	3.213ValPro: 3.213 ± 0.019	2.428ValGln: 2.428 ± 0.014	3.307ValArg: 3.307 ± 0.02	5.368ValSer: 5.368 ± 0.023	3.227ValThr: 3.227 ± 0.017	5.393ValVal: 5.393 ± 0.031	0.816ValTrp: 0.816 ± 0.008	1.896ValTyr: 1.896 ± 0.014	0.001ValXaa: 0.001 ± 0.0
Trp	0.742TrpAla: 0.742 ± 0.008	0.273TrpCys: 0.273 ± 0.004	0.642TrpAsp: 0.642 ± 0.008	0.735TrpGlu: 0.735 ± 0.009	0.567TrpPhe: 0.567 ± 0.007	0.723TrpGly: 0.723 ± 0.009	0.284TrpHis: 0.284 ± 0.004	0.712TrpIle: 0.712 ± 0.007	0.948TrpLys: 0.948 ± 0.01	1.202TrpLeu: 1.202 ± 0.01	0.391TrpMet: 0.391 ± 0.006	0.71TrpAsn: 0.71 ± 0.008	0.529TrpPro: 0.529 ± 0.007	0.468TrpGln: 0.468 ± 0.006	0.882TrpArg: 0.882 ± 0.01	0.96TrpSer: 0.96 ± 0.009	0.802TrpThr: 0.802 ± 0.013	0.844TrpVal: 0.844 ± 0.009	0.261TrpTrp: 0.261 ± 0.005	0.33TrpTyr: 0.33 ± 0.005	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.699TyrAla: 1.699 ± 0.014	0.645TyrCys: 0.645 ± 0.007	1.517TyrAsp: 1.517 ± 0.013	1.546TyrGlu: 1.546 ± 0.013	1.232TyrPhe: 1.232 ± 0.01	2.031TyrGly: 2.031 ± 0.014	0.675TyrHis: 0.675 ± 0.009	1.354TyrIle: 1.354 ± 0.012	1.423TyrLys: 1.423 ± 0.014	2.599TyrLeu: 2.599 ± 0.015	0.739TyrMet: 0.739 ± 0.008	1.248TyrAsn: 1.248 ± 0.012	1.269TyrPro: 1.269 ± 0.01	0.857TyrGln: 0.857 ± 0.009	1.376TyrArg: 1.376 ± 0.013	2.138TyrSer: 2.138 ± 0.015	1.26TyrThr: 1.26 ± 0.012	1.781TyrVal: 1.781 ± 0.014	0.417TyrTrp: 0.417 ± 0.006	0.957TyrTyr: 0.957 ± 0.015	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.001XaaAla: 0.001 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.001XaaGlu: 0.001 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.001XaaGly: 0.001 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.001XaaLys: 0.001 ± 0.0	0.002XaaLeu: 0.002 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.001XaaPro: 0.001 ± 0.0	0.001XaaGln: 0.001 ± 0.0	0.001XaaArg: 0.001 ± 0.0	0.001XaaSer: 0.001 ± 0.0	0.001XaaThr: 0.001 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.449XaaXaa: 0.449 ± 0.07

Statistics based on 33730 proteins (12545473 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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