Amino acid dipepetide frequency for Serendipita indica (strain DSM 11827) (Root endophyte fungus) (Piriformospora indica)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.042AlaAla: 8.042 ± 0.062	0.969AlaCys: 0.969 ± 0.015	3.691AlaAsp: 3.691 ± 0.027	4.53AlaGlu: 4.53 ± 0.035	3.171AlaPhe: 3.171 ± 0.032	5.004AlaGly: 5.004 ± 0.043	2.026AlaHis: 2.026 ± 0.02	4.386AlaIle: 4.386 ± 0.029	3.832AlaLys: 3.832 ± 0.036	8.118AlaLeu: 8.118 ± 0.046	1.911AlaMet: 1.911 ± 0.02	3.012AlaAsn: 3.012 ± 0.027	5.125AlaPro: 5.125 ± 0.049	3.354AlaGln: 3.354 ± 0.03	4.988AlaArg: 4.988 ± 0.033	7.872AlaSer: 7.872 ± 0.057	5.491AlaThr: 5.491 ± 0.032	5.15AlaVal: 5.15 ± 0.037	1.078AlaTrp: 1.078 ± 0.016	2.143AlaTyr: 2.143 ± 0.021	0.001AlaXaa: 0.001 ± 0.0
Cys	0.822CysAla: 0.822 ± 0.013	0.191CysCys: 0.191 ± 0.006	0.618CysAsp: 0.618 ± 0.011	0.547CysGlu: 0.547 ± 0.011	0.457CysPhe: 0.457 ± 0.01	0.855CysGly: 0.855 ± 0.017	0.305CysHis: 0.305 ± 0.007	0.699CysIle: 0.699 ± 0.013	0.511CysLys: 0.511 ± 0.011	1.183CysLeu: 1.183 ± 0.018	0.24CysMet: 0.24 ± 0.007	0.379CysAsn: 0.379 ± 0.01	0.638CysPro: 0.638 ± 0.013	0.414CysGln: 0.414 ± 0.01	0.737CysArg: 0.737 ± 0.013	0.889CysSer: 0.889 ± 0.017	0.698CysThr: 0.698 ± 0.012	0.705CysVal: 0.705 ± 0.012	0.19CysTrp: 0.19 ± 0.006	0.307CysTyr: 0.307 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	4.781AspAla: 4.781 ± 0.033	0.545AspCys: 0.545 ± 0.012	3.758AspAsp: 3.758 ± 0.032	4.305AspGlu: 4.305 ± 0.039	1.769AspPhe: 1.769 ± 0.02	3.887AspGly: 3.887 ± 0.038	1.179AspHis: 1.179 ± 0.017	3.069AspIle: 3.069 ± 0.029	2.199AspLys: 2.199 ± 0.02	4.738AspLeu: 4.738 ± 0.035	1.18AspMet: 1.18 ± 0.015	1.701AspAsn: 1.701 ± 0.018	3.211AspPro: 3.211 ± 0.026	1.744AspGln: 1.744 ± 0.018	2.702AspArg: 2.702 ± 0.023	4.01AspSer: 4.01 ± 0.031	2.934AspThr: 2.934 ± 0.024	3.598AspVal: 3.598 ± 0.028	0.844AspTrp: 0.844 ± 0.012	1.418AspTyr: 1.418 ± 0.017	0.0AspXaa: 0.0 ± 0.0
Glu	4.973GluAla: 4.973 ± 0.036	0.654GluCys: 0.654 ± 0.014	4.037GluAsp: 4.037 ± 0.041	5.468GluGlu: 5.468 ± 0.052	1.761GluPhe: 1.761 ± 0.018	3.431GluGly: 3.431 ± 0.028	1.416GluHis: 1.416 ± 0.017	2.955GluIle: 2.955 ± 0.031	3.095GluLys: 3.095 ± 0.03	5.253GluLeu: 5.253 ± 0.043	1.436GluMet: 1.436 ± 0.018	1.997GluAsn: 1.997 ± 0.023	2.854GluPro: 2.854 ± 0.027	2.359GluGln: 2.359 ± 0.024	4.162GluArg: 4.162 ± 0.038	4.268GluSer: 4.268 ± 0.03	3.437GluThr: 3.437 ± 0.032	3.325GluVal: 3.325 ± 0.031	0.931GluTrp: 0.931 ± 0.014	1.634GluTyr: 1.634 ± 0.018	0.0GluXaa: 0.0 ± 0.0
Phe	2.851PheAla: 2.851 ± 0.023	0.487PheCys: 0.487 ± 0.01	2.098PheAsp: 2.098 ± 0.023	1.984PheGlu: 1.984 ± 0.02	1.474PhePhe: 1.474 ± 0.019	2.583PheGly: 2.583 ± 0.03	0.893PheHis: 0.893 ± 0.012	1.868PheIle: 1.868 ± 0.022	1.428PheLys: 1.428 ± 0.018	3.196PheLeu: 3.196 ± 0.032	0.72PheMet: 0.72 ± 0.012	1.29PheAsn: 1.29 ± 0.018	1.897PhePro: 1.897 ± 0.02	1.208PheGln: 1.208 ± 0.016	1.844PheArg: 1.844 ± 0.019	3.056PheSer: 3.056 ± 0.033	2.135PheThr: 2.135 ± 0.021	2.317PheVal: 2.317 ± 0.023	0.584PheTrp: 0.584 ± 0.012	1.009PheTyr: 1.009 ± 0.014	0.0PheXaa: 0.0 ± 0.0
Gly	4.936GlyAla: 4.936 ± 0.041	0.737GlyCys: 0.737 ± 0.013	3.225GlyAsp: 3.225 ± 0.025	3.388GlyGlu: 3.388 ± 0.029	2.364GlyPhe: 2.364 ± 0.026	5.236GlyGly: 5.236 ± 0.052	1.849GlyHis: 1.849 ± 0.027	3.271GlyIle: 3.271 ± 0.028	3.014GlyLys: 3.014 ± 0.03	5.533GlyLeu: 5.533 ± 0.035	1.452GlyMet: 1.452 ± 0.017	2.235GlyAsn: 2.235 ± 0.024	3.246GlyPro: 3.246 ± 0.029	2.461GlyGln: 2.461 ± 0.028	3.863GlyArg: 3.863 ± 0.029	6.128GlySer: 6.128 ± 0.054	4.023GlyThr: 4.023 ± 0.033	4.019GlyVal: 4.019 ± 0.034	1.043GlyTrp: 1.043 ± 0.017	1.893GlyTyr: 1.893 ± 0.022	0.002GlyXaa: 0.002 ± 0.001
His	2.047HisAla: 2.047 ± 0.019	0.299HisCys: 0.299 ± 0.008	1.256HisAsp: 1.256 ± 0.016	1.296HisGlu: 1.296 ± 0.017	0.909HisPhe: 0.909 ± 0.014	1.698HisGly: 1.698 ± 0.02	0.968HisHis: 0.968 ± 0.018	1.363HisIle: 1.363 ± 0.019	0.907HisLys: 0.907 ± 0.013	2.581HisLeu: 2.581 ± 0.027	0.449HisMet: 0.449 ± 0.009	0.831HisAsn: 0.831 ± 0.014	1.931HisPro: 1.931 ± 0.023	1.049HisGln: 1.049 ± 0.016	1.644HisArg: 1.644 ± 0.018	2.215HisSer: 2.215 ± 0.025	1.442HisThr: 1.442 ± 0.017	1.523HisVal: 1.523 ± 0.015	0.382HisTrp: 0.382 ± 0.01	0.683HisTyr: 0.683 ± 0.012	0.0HisXaa: 0.0 ± 0.0
Ile	4.171IleAla: 4.171 ± 0.032	0.754IleCys: 0.754 ± 0.013	2.803IleAsp: 2.803 ± 0.027	2.835IleGlu: 2.835 ± 0.027	1.903IlePhe: 1.903 ± 0.02	2.972IleGly: 2.972 ± 0.027	1.339IleHis: 1.339 ± 0.016	2.58IleIle: 2.58 ± 0.027	2.223IleLys: 2.223 ± 0.021	4.924IleLeu: 4.924 ± 0.036	0.968IleMet: 0.968 ± 0.014	1.767IleAsn: 1.767 ± 0.017	3.321IlePro: 3.321 ± 0.026	2.077IleGln: 2.077 ± 0.021	3.147IleArg: 3.147 ± 0.025	4.166IleSer: 4.166 ± 0.034	2.914IleThr: 2.914 ± 0.026	3.383IleVal: 3.383 ± 0.025	0.804IleTrp: 0.804 ± 0.013	1.382IleTyr: 1.382 ± 0.017	0.0IleXaa: 0.0 ± 0.0
Lys	4.047LysAla: 4.047 ± 0.035	0.455LysCys: 0.455 ± 0.011	2.474LysAsp: 2.474 ± 0.025	3.224LysGlu: 3.224 ± 0.035	1.311LysPhe: 1.311 ± 0.017	2.715LysGly: 2.715 ± 0.027	1.084LysHis: 1.084 ± 0.016	2.033LysIle: 2.033 ± 0.021	2.798LysLys: 2.798 ± 0.038	3.991LysLeu: 3.991 ± 0.032	0.991LysMet: 0.991 ± 0.014	1.42LysAsn: 1.42 ± 0.018	2.697LysPro: 2.697 ± 0.027	1.737LysGln: 1.737 ± 0.019	3.617LysArg: 3.617 ± 0.03	3.378LysSer: 3.378 ± 0.025	2.683LysThr: 2.683 ± 0.024	2.624LysVal: 2.624 ± 0.027	0.676LysTrp: 0.676 ± 0.013	1.199LysTyr: 1.199 ± 0.017	0.001LysXaa: 0.001 ± 0.0
Leu	7.922LeuAla: 7.922 ± 0.041	1.204LeuCys: 1.204 ± 0.018	5.282LeuAsp: 5.282 ± 0.036	5.868LeuGlu: 5.868 ± 0.054	3.392LeuPhe: 3.392 ± 0.031	5.699LeuGly: 5.699 ± 0.04	2.454LeuHis: 2.454 ± 0.026	3.988LeuIle: 3.988 ± 0.035	4.175LeuLys: 4.175 ± 0.035	8.678LeuLeu: 8.678 ± 0.063	1.685LeuMet: 1.685 ± 0.018	3.151LeuAsn: 3.151 ± 0.022	6.068LeuPro: 6.068 ± 0.036	3.956LeuGln: 3.956 ± 0.033	6.301LeuArg: 6.301 ± 0.049	7.878LeuSer: 7.878 ± 0.05	5.105LeuThr: 5.105 ± 0.037	5.887LeuVal: 5.887 ± 0.039	1.406LeuTrp: 1.406 ± 0.026	2.417LeuTyr: 2.417 ± 0.023	0.001LeuXaa: 0.001 ± 0.0
Met	1.95MetAla: 1.95 ± 0.019	0.22MetCys: 0.22 ± 0.007	1.298MetAsp: 1.298 ± 0.017	1.368MetGlu: 1.368 ± 0.017	0.657MetPhe: 0.657 ± 0.012	1.288MetGly: 1.288 ± 0.02	0.529MetHis: 0.529 ± 0.01	0.952MetIle: 0.952 ± 0.013	0.897MetLys: 0.897 ± 0.014	1.844MetLeu: 1.844 ± 0.021	0.524MetMet: 0.524 ± 0.012	0.798MetAsn: 0.798 ± 0.014	1.276MetPro: 1.276 ± 0.017	0.866MetGln: 0.866 ± 0.014	1.356MetArg: 1.356 ± 0.016	2.088MetSer: 2.088 ± 0.019	1.289MetThr: 1.289 ± 0.018	1.168MetVal: 1.168 ± 0.014	0.248MetTrp: 0.248 ± 0.008	0.5MetTyr: 0.5 ± 0.01	0.0MetXaa: 0.0 ± 0.0
Asn	3.325AsnAla: 3.325 ± 0.03	0.354AsnCys: 0.354 ± 0.009	1.764AsnAsp: 1.764 ± 0.019	1.922AsnGlu: 1.922 ± 0.021	1.129AsnPhe: 1.129 ± 0.016	2.719AsnGly: 2.719 ± 0.029	0.82AsnHis: 0.82 ± 0.013	1.892AsnIle: 1.892 ± 0.017	1.413AsnLys: 1.413 ± 0.019	3.366AsnLeu: 3.366 ± 0.03	0.746AsnMet: 0.746 ± 0.013	1.32AsnAsn: 1.32 ± 0.02	2.433AsnPro: 2.433 ± 0.025	1.354AsnGln: 1.354 ± 0.018	1.929AsnArg: 1.929 ± 0.018	2.793AsnSer: 2.793 ± 0.03	2.22AsnThr: 2.22 ± 0.028	2.378AsnVal: 2.378 ± 0.024	0.511AsnTrp: 0.511 ± 0.01	0.936AsnTyr: 0.936 ± 0.014	0.0AsnXaa: 0.0 ± 0.0
Pro	5.106ProAla: 5.106 ± 0.053	0.47ProCys: 0.47 ± 0.01	3.043ProAsp: 3.043 ± 0.031	3.432ProGlu: 3.432 ± 0.027	2.102ProPhe: 2.102 ± 0.021	3.643ProGly: 3.643 ± 0.035	1.521ProHis: 1.521 ± 0.019	2.937ProIle: 2.937 ± 0.024	2.635ProLys: 2.635 ± 0.026	5.717ProLeu: 5.717 ± 0.04	1.186ProMet: 1.186 ± 0.015	2.469ProAsn: 2.469 ± 0.024	6.14ProPro: 6.14 ± 0.076	2.361ProGln: 2.361 ± 0.03	3.703ProArg: 3.703 ± 0.036	7.035ProSer: 7.035 ± 0.063	4.749ProThr: 4.749 ± 0.04	3.886ProVal: 3.886 ± 0.03	0.714ProTrp: 0.714 ± 0.011	1.602ProTyr: 1.602 ± 0.021	0.001ProXaa: 0.001 ± 0.001
Gln	3.4GlnAla: 3.4 ± 0.029	0.445GlnCys: 0.445 ± 0.008	1.876GlnAsp: 1.876 ± 0.021	2.375GlnGlu: 2.375 ± 0.025	1.266GlnPhe: 1.266 ± 0.016	2.256GlnGly: 2.256 ± 0.021	1.059GlnHis: 1.059 ± 0.016	1.894GlnIle: 1.894 ± 0.021	1.656GlnLys: 1.656 ± 0.02	3.597GlnLeu: 3.597 ± 0.029	0.87GlnMet: 0.87 ± 0.014	1.384GlnAsn: 1.384 ± 0.017	2.597GlnPro: 2.597 ± 0.031	2.174GlnGln: 2.174 ± 0.041	2.89GlnArg: 2.89 ± 0.027	3.219GlnSer: 3.219 ± 0.027	2.49GlnThr: 2.49 ± 0.024	2.157GlnVal: 2.157 ± 0.022	0.538GlnTrp: 0.538 ± 0.011	1.108GlnTyr: 1.108 ± 0.015	0.001GlnXaa: 0.001 ± 0.0
Arg	5.018ArgAla: 5.018 ± 0.033	0.7ArgCys: 0.7 ± 0.012	3.163ArgAsp: 3.163 ± 0.032	3.739ArgGlu: 3.739 ± 0.036	2.168ArgPhe: 2.168 ± 0.022	3.72ArgGly: 3.72 ± 0.033	1.729ArgHis: 1.729 ± 0.021	3.382ArgIle: 3.382 ± 0.028	3.311ArgLys: 3.311 ± 0.03	6.145ArgLeu: 6.145 ± 0.047	1.426ArgMet: 1.426 ± 0.015	2.158ArgAsn: 2.158 ± 0.02	3.867ArgPro: 3.867 ± 0.035	2.587ArgGln: 2.587 ± 0.027	5.458ArgArg: 5.458 ± 0.047	5.183ArgSer: 5.183 ± 0.042	3.612ArgThr: 3.612 ± 0.027	3.638ArgVal: 3.638 ± 0.027	0.944ArgTrp: 0.944 ± 0.014	1.651ArgTyr: 1.651 ± 0.019	0.001ArgXaa: 0.001 ± 0.0
Ser	6.845SerAla: 6.845 ± 0.045	0.822SerCys: 0.822 ± 0.015	4.107SerAsp: 4.107 ± 0.03	4.038SerGlu: 4.038 ± 0.029	3.022SerPhe: 3.022 ± 0.027	5.78SerGly: 5.78 ± 0.047	2.16SerHis: 2.16 ± 0.025	4.425SerIle: 4.425 ± 0.03	3.824SerLys: 3.824 ± 0.03	8.001SerLeu: 8.001 ± 0.051	1.873SerMet: 1.873 ± 0.021	3.339SerAsn: 3.339 ± 0.028	6.361SerPro: 6.361 ± 0.068	3.404SerGln: 3.404 ± 0.028	5.538SerArg: 5.538 ± 0.046	10.612SerSer: 10.612 ± 0.098	7.036SerThr: 7.036 ± 0.059	5.037SerVal: 5.037 ± 0.039	1.104SerTrp: 1.104 ± 0.016	2.039SerTyr: 2.039 ± 0.022	0.001SerXaa: 0.001 ± 0.0
Thr	5.082ThrAla: 5.082 ± 0.033	0.72ThrCys: 0.72 ± 0.016	2.692ThrAsp: 2.692 ± 0.023	2.976ThrGlu: 2.976 ± 0.026	2.288ThrPhe: 2.288 ± 0.024	4.042ThrGly: 4.042 ± 0.035	1.453ThrHis: 1.453 ± 0.016	3.452ThrIle: 3.452 ± 0.034	2.617ThrLys: 2.617 ± 0.026	6.125ThrLeu: 6.125 ± 0.038	1.277ThrMet: 1.277 ± 0.015	2.22ThrAsn: 2.22 ± 0.022	4.845ThrPro: 4.845 ± 0.046	2.19ThrGln: 2.19 ± 0.022	3.757ThrArg: 3.757 ± 0.028	6.42ThrSer: 6.42 ± 0.051	4.826ThrThr: 4.826 ± 0.048	3.926ThrVal: 3.926 ± 0.031	0.829ThrTrp: 0.829 ± 0.013	1.587ThrTyr: 1.587 ± 0.019	0.001ThrXaa: 0.001 ± 0.0
Val	5.357ValAla: 5.357 ± 0.035	0.781ValCys: 0.781 ± 0.013	3.785ValAsp: 3.785 ± 0.027	3.905ValGlu: 3.905 ± 0.027	2.239ValPhe: 2.239 ± 0.021	3.704ValGly: 3.704 ± 0.028	1.621ValHis: 1.621 ± 0.019	3.069ValIle: 3.069 ± 0.028	2.751ValLys: 2.751 ± 0.027	5.738ValLeu: 5.738 ± 0.036	1.223ValMet: 1.223 ± 0.013	2.141ValAsn: 2.141 ± 0.025	3.787ValPro: 3.787 ± 0.028	2.449ValGln: 2.449 ± 0.024	3.434ValArg: 3.434 ± 0.027	4.891ValSer: 4.891 ± 0.037	3.602ValThr: 3.602 ± 0.029	4.218ValVal: 4.218 ± 0.033	0.877ValTrp: 0.877 ± 0.014	1.771ValTyr: 1.771 ± 0.02	0.001ValXaa: 0.001 ± 0.0
Trp	1.069TrpAla: 1.069 ± 0.014	0.222TrpCys: 0.222 ± 0.007	1.03TrpAsp: 1.03 ± 0.023	0.82TrpGlu: 0.82 ± 0.012	0.518TrpPhe: 0.518 ± 0.01	0.782TrpGly: 0.782 ± 0.013	0.346TrpHis: 0.346 ± 0.009	0.79TrpIle: 0.79 ± 0.013	0.812TrpLys: 0.812 ± 0.015	1.273TrpLeu: 1.273 ± 0.018	0.375TrpMet: 0.375 ± 0.009	0.662TrpAsn: 0.662 ± 0.012	0.596TrpPro: 0.596 ± 0.011	0.488TrpGln: 0.488 ± 0.01	0.984TrpArg: 0.984 ± 0.014	1.159TrpSer: 1.159 ± 0.016	0.968TrpThr: 0.968 ± 0.013	0.86TrpVal: 0.86 ± 0.015	0.275TrpTrp: 0.275 ± 0.008	0.37TrpTyr: 0.37 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.147TyrAla: 2.147 ± 0.022	0.356TyrCys: 0.356 ± 0.009	1.573TyrAsp: 1.573 ± 0.018	1.424TyrGlu: 1.424 ± 0.017	1.02TyrPhe: 1.02 ± 0.015	1.9TyrGly: 1.9 ± 0.023	0.719TyrHis: 0.719 ± 0.011	1.431TyrIle: 1.431 ± 0.015	1.055TyrLys: 1.055 ± 0.017	2.515TyrLeu: 2.515 ± 0.023	0.584TyrMet: 0.584 ± 0.01	1.05TyrAsn: 1.05 ± 0.015	1.561TyrPro: 1.561 ± 0.022	1.022TyrGln: 1.022 ± 0.016	1.547TyrArg: 1.547 ± 0.018	2.107TyrSer: 2.107 ± 0.022	1.67TyrThr: 1.67 ± 0.021	1.548TyrVal: 1.548 ± 0.021	0.421TyrTrp: 0.421 ± 0.01	0.838TyrTyr: 0.838 ± 0.013	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.001XaaAla: 0.001 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.001XaaGlu: 0.001 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.002XaaGly: 0.002 ± 0.001	0.0XaaHis: 0.0 ± 0.0	0.001XaaIle: 0.001 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.001XaaMet: 0.001 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.001XaaPro: 0.001 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.001XaaArg: 0.001 ± 0.0	0.002XaaSer: 0.002 ± 0.001	0.0XaaThr: 0.0 ± 0.0	0.001XaaVal: 0.001 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.604XaaXaa: 0.604 ± 0.161

Statistics based on 11780 proteins (5140652 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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