Amino acid dipepetide frequency for Salegentibacter flavus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	4.701AlaAla: 4.701 ± 0.081	0.533AlaCys: 0.533 ± 0.023	3.211AlaAsp: 3.211 ± 0.058	5.203AlaGlu: 5.203 ± 0.069	3.314AlaPhe: 3.314 ± 0.058	4.771AlaGly: 4.771 ± 0.076	1.148AlaHis: 1.148 ± 0.033	5.169AlaIle: 5.169 ± 0.077	4.22AlaLys: 4.22 ± 0.075	6.294AlaLeu: 6.294 ± 0.103	1.713AlaMet: 1.713 ± 0.04	2.976AlaAsn: 2.976 ± 0.053	1.929AlaPro: 1.929 ± 0.044	2.316AlaGln: 2.316 ± 0.05	2.659AlaArg: 2.659 ± 0.061	4.034AlaSer: 4.034 ± 0.071	3.291AlaThr: 3.291 ± 0.065	4.276AlaVal: 4.276 ± 0.071	0.665AlaTrp: 0.665 ± 0.027	2.437AlaTyr: 2.437 ± 0.051	0.0AlaXaa: 0.0 ± 0.0
Cys	0.378CysAla: 0.378 ± 0.017	0.089CysCys: 0.089 ± 0.01	0.386CysAsp: 0.386 ± 0.02	0.479CysGlu: 0.479 ± 0.027	0.344CysPhe: 0.344 ± 0.016	0.541CysGly: 0.541 ± 0.024	0.162CysHis: 0.162 ± 0.012	0.445CysIle: 0.445 ± 0.022	0.393CysLys: 0.393 ± 0.02	0.555CysLeu: 0.555 ± 0.023	0.127CysMet: 0.127 ± 0.01	0.309CysAsn: 0.309 ± 0.017	0.314CysPro: 0.314 ± 0.018	0.181CysGln: 0.181 ± 0.014	0.232CysArg: 0.232 ± 0.014	0.471CysSer: 0.471 ± 0.024	0.33CysThr: 0.33 ± 0.017	0.367CysVal: 0.367 ± 0.021	0.065CysTrp: 0.065 ± 0.007	0.249CysTyr: 0.249 ± 0.016	0.0CysXaa: 0.0 ± 0.0
Asp	3.516AspAla: 3.516 ± 0.069	0.349AspCys: 0.349 ± 0.021	2.758AspAsp: 2.758 ± 0.061	4.339AspGlu: 4.339 ± 0.071	3.756AspPhe: 3.756 ± 0.065	3.579AspGly: 3.579 ± 0.072	1.045AspHis: 1.045 ± 0.033	4.105AspIle: 4.105 ± 0.059	3.982AspLys: 3.982 ± 0.07	5.558AspLeu: 5.558 ± 0.078	1.184AspMet: 1.184 ± 0.036	2.662AspAsn: 2.662 ± 0.057	2.102AspPro: 2.102 ± 0.053	1.681AspGln: 1.681 ± 0.043	2.283AspArg: 2.283 ± 0.044	3.126AspSer: 3.126 ± 0.058	2.409AspThr: 2.409 ± 0.049	3.275AspVal: 3.275 ± 0.068	0.762AspTrp: 0.762 ± 0.025	2.8AspTyr: 2.8 ± 0.059	0.0AspXaa: 0.0 ± 0.0
Glu	5.199GluAla: 5.199 ± 0.077	0.353GluCys: 0.353 ± 0.02	4.655GluAsp: 4.655 ± 0.072	7.513GluGlu: 7.513 ± 0.11	3.614GluPhe: 3.614 ± 0.064	4.351GluGly: 4.351 ± 0.07	1.285GluHis: 1.285 ± 0.037	6.663GluIle: 6.663 ± 0.088	7.072GluLys: 7.072 ± 0.096	7.134GluLeu: 7.134 ± 0.087	1.938GluMet: 1.938 ± 0.042	5.357GluAsn: 5.357 ± 0.074	1.964GluPro: 1.964 ± 0.051	2.443GluGln: 2.443 ± 0.05	2.995GluArg: 2.995 ± 0.055	3.659GluSer: 3.659 ± 0.061	3.87GluThr: 3.87 ± 0.065	5.08GluVal: 5.08 ± 0.067	0.716GluTrp: 0.716 ± 0.027	2.718GluTyr: 2.718 ± 0.055	0.0GluXaa: 0.0 ± 0.0
Phe	2.976PheAla: 2.976 ± 0.055	0.423PheCys: 0.423 ± 0.02	3.055PheAsp: 3.055 ± 0.052	3.841PheGlu: 3.841 ± 0.057	2.776PhePhe: 2.776 ± 0.063	3.624PheGly: 3.624 ± 0.067	0.87PheHis: 0.87 ± 0.03	3.714PheIle: 3.714 ± 0.062	3.53PheLys: 3.53 ± 0.059	5.09PheLeu: 5.09 ± 0.089	1.152PheMet: 1.152 ± 0.035	2.867PheAsn: 2.867 ± 0.064	1.848PhePro: 1.848 ± 0.041	1.704PheGln: 1.704 ± 0.038	2.026PheArg: 2.026 ± 0.046	4.127PheSer: 4.127 ± 0.072	2.798PheThr: 2.798 ± 0.047	2.721PheVal: 2.721 ± 0.057	0.605PheTrp: 0.605 ± 0.025	2.014PheTyr: 2.014 ± 0.047	0.0PheXaa: 0.0 ± 0.0
Gly	4.216GlyAla: 4.216 ± 0.08	0.531GlyCys: 0.531 ± 0.021	3.557GlyAsp: 3.557 ± 0.062	4.601GlyGlu: 4.601 ± 0.07	3.656GlyPhe: 3.656 ± 0.062	4.681GlyGly: 4.681 ± 0.09	1.16GlyHis: 1.16 ± 0.039	5.6GlyIle: 5.6 ± 0.083	5.147GlyLys: 5.147 ± 0.074	5.926GlyLeu: 5.926 ± 0.077	1.803GlyMet: 1.803 ± 0.04	3.585GlyAsn: 3.585 ± 0.065	1.514GlyPro: 1.514 ± 0.038	1.861GlyGln: 1.861 ± 0.048	2.429GlyArg: 2.429 ± 0.052	3.966GlySer: 3.966 ± 0.064	3.624GlyThr: 3.624 ± 0.067	4.333GlyVal: 4.333 ± 0.071	0.826GlyTrp: 0.826 ± 0.032	2.738GlyTyr: 2.738 ± 0.057	0.0GlyXaa: 0.0 ± 0.0
His	0.904HisAla: 0.904 ± 0.029	0.153HisCys: 0.153 ± 0.011	0.777HisAsp: 0.777 ± 0.028	1.004HisGlu: 1.004 ± 0.033	1.113HisPhe: 1.113 ± 0.031	1.11HisGly: 1.11 ± 0.037	0.496HisHis: 0.496 ± 0.019	1.352HisIle: 1.352 ± 0.035	1.165HisLys: 1.165 ± 0.034	1.925HisLeu: 1.925 ± 0.046	0.329HisMet: 0.329 ± 0.016	0.915HisAsn: 0.915 ± 0.027	1.06HisPro: 1.06 ± 0.032	0.78HisGln: 0.78 ± 0.028	0.825HisArg: 0.825 ± 0.028	1.151HisSer: 1.151 ± 0.039	0.9HisThr: 0.9 ± 0.031	0.844HisVal: 0.844 ± 0.031	0.254HisTrp: 0.254 ± 0.014	0.804HisTyr: 0.804 ± 0.033	0.0HisXaa: 0.0 ± 0.0
Ile	5.473IleAla: 5.473 ± 0.087	0.506IleCys: 0.506 ± 0.025	4.542IleAsp: 4.542 ± 0.066	5.574IleGlu: 5.574 ± 0.078	3.834IlePhe: 3.834 ± 0.065	5.0IleGly: 5.0 ± 0.08	1.285IleHis: 1.285 ± 0.037	5.65IleIle: 5.65 ± 0.082	5.416IleLys: 5.416 ± 0.081	7.386IleLeu: 7.386 ± 0.096	1.318IleMet: 1.318 ± 0.034	4.072IleAsn: 4.072 ± 0.071	3.412IlePro: 3.412 ± 0.052	2.43IleGln: 2.43 ± 0.052	2.882IleArg: 2.882 ± 0.046	5.687IleSer: 5.687 ± 0.08	4.201IleThr: 4.201 ± 0.067	4.02IleVal: 4.02 ± 0.071	0.704IleTrp: 0.704 ± 0.029	2.839IleTyr: 2.839 ± 0.058	0.0IleXaa: 0.0 ± 0.0
Lys	4.894LysAla: 4.894 ± 0.07	0.289LysCys: 0.289 ± 0.015	4.491LysAsp: 4.491 ± 0.07	6.629LysGlu: 6.629 ± 0.097	2.966LysPhe: 2.966 ± 0.053	4.225LysGly: 4.225 ± 0.065	1.297LysHis: 1.297 ± 0.041	5.925LysIle: 5.925 ± 0.088	6.602LysLys: 6.602 ± 0.097	6.785LysLeu: 6.785 ± 0.086	1.93LysMet: 1.93 ± 0.041	4.729LysAsn: 4.729 ± 0.075	2.471LysPro: 2.471 ± 0.047	2.456LysGln: 2.456 ± 0.056	3.083LysArg: 3.083 ± 0.059	4.116LysSer: 4.116 ± 0.065	4.169LysThr: 4.169 ± 0.072	4.318LysVal: 4.318 ± 0.065	0.719LysTrp: 0.719 ± 0.025	2.926LysTyr: 2.926 ± 0.054	0.0LysXaa: 0.0 ± 0.0
Leu	6.163LeuAla: 6.163 ± 0.083	0.58LeuCys: 0.58 ± 0.024	5.242LeuAsp: 5.242 ± 0.081	7.545LeuGlu: 7.545 ± 0.095	4.776LeuPhe: 4.776 ± 0.073	6.122LeuGly: 6.122 ± 0.096	1.669LeuHis: 1.669 ± 0.044	7.001LeuIle: 7.001 ± 0.097	7.878LeuLys: 7.878 ± 0.105	9.211LeuLeu: 9.211 ± 0.13	2.252LeuMet: 2.252 ± 0.044	5.37LeuAsn: 5.37 ± 0.082	3.788LeuPro: 3.788 ± 0.06	3.515LeuGln: 3.515 ± 0.061	3.806LeuArg: 3.806 ± 0.065	6.784LeuSer: 6.784 ± 0.086	4.622LeuThr: 4.622 ± 0.07	5.625LeuVal: 5.625 ± 0.089	0.867LeuTrp: 0.867 ± 0.029	3.129LeuTyr: 3.129 ± 0.064	0.0LeuXaa: 0.0 ± 0.0
Met	1.779MetAla: 1.779 ± 0.039	0.109MetCys: 0.109 ± 0.009	1.273MetAsp: 1.273 ± 0.039	1.834MetGlu: 1.834 ± 0.044	0.866MetPhe: 0.866 ± 0.029	1.541MetGly: 1.541 ± 0.04	0.378MetHis: 0.378 ± 0.019	1.588MetIle: 1.588 ± 0.038	2.19MetLys: 2.19 ± 0.045	2.173MetLeu: 2.173 ± 0.049	0.599MetMet: 0.599 ± 0.025	1.264MetAsn: 1.264 ± 0.031	0.869MetPro: 0.869 ± 0.029	0.902MetGln: 0.902 ± 0.027	0.963MetArg: 0.963 ± 0.026	1.301MetSer: 1.301 ± 0.032	0.989MetThr: 0.989 ± 0.031	1.441MetVal: 1.441 ± 0.034	0.174MetTrp: 0.174 ± 0.013	0.664MetTyr: 0.664 ± 0.028	0.0MetXaa: 0.0 ± 0.0
Asn	3.357AsnAla: 3.357 ± 0.052	0.361AsnCys: 0.361 ± 0.02	2.767AsnAsp: 2.767 ± 0.053	3.675AsnGlu: 3.675 ± 0.053	3.115AsnPhe: 3.115 ± 0.066	3.265AsnGly: 3.265 ± 0.069	0.972AsnHis: 0.972 ± 0.031	4.394AsnIle: 4.394 ± 0.079	3.76AsnLys: 3.76 ± 0.057	5.556AsnLeu: 5.556 ± 0.081	1.241AsnMet: 1.241 ± 0.037	2.992AsnAsn: 2.992 ± 0.065	2.701AsnPro: 2.701 ± 0.052	1.965AsnGln: 1.965 ± 0.042	2.422AsnArg: 2.422 ± 0.045	3.546AsnSer: 3.546 ± 0.065	2.99AsnThr: 2.99 ± 0.056	2.902AsnVal: 2.902 ± 0.06	0.744AsnTrp: 0.744 ± 0.026	2.598AsnTyr: 2.598 ± 0.057	0.0AsnXaa: 0.0 ± 0.0
Pro	2.17ProAla: 2.17 ± 0.049	0.181ProCys: 0.181 ± 0.013	2.386ProAsp: 2.386 ± 0.048	3.831ProGlu: 3.831 ± 0.064	1.848ProPhe: 1.848 ± 0.041	2.606ProGly: 2.606 ± 0.048	0.648ProHis: 0.648 ± 0.025	2.392ProIle: 2.392 ± 0.049	2.344ProLys: 2.344 ± 0.049	3.115ProLeu: 3.115 ± 0.059	0.797ProMet: 0.797 ± 0.029	1.894ProAsn: 1.894 ± 0.046	0.965ProPro: 0.965 ± 0.032	1.354ProGln: 1.354 ± 0.033	1.13ProArg: 1.13 ± 0.025	2.052ProSer: 2.052 ± 0.044	1.676ProThr: 1.676 ± 0.039	2.896ProVal: 2.896 ± 0.05	0.354ProTrp: 0.354 ± 0.02	1.364ProTyr: 1.364 ± 0.036	0.0ProXaa: 0.0 ± 0.0
Gln	2.271GlnAla: 2.271 ± 0.049	0.147GlnCys: 0.147 ± 0.013	1.732GlnAsp: 1.732 ± 0.042	2.901GlnGlu: 2.901 ± 0.055	1.476GlnPhe: 1.476 ± 0.033	1.955GlnGly: 1.955 ± 0.049	0.627GlnHis: 0.627 ± 0.026	2.508GlnIle: 2.508 ± 0.051	2.828GlnLys: 2.828 ± 0.055	3.511GlnLeu: 3.511 ± 0.063	0.822GlnMet: 0.822 ± 0.029	2.107GlnAsn: 2.107 ± 0.046	1.169GlnPro: 1.169 ± 0.034	1.58GlnGln: 1.58 ± 0.046	1.424GlnArg: 1.424 ± 0.037	1.744GlnSer: 1.744 ± 0.041	1.73GlnThr: 1.73 ± 0.043	2.082GlnVal: 2.082 ± 0.044	0.355GlnTrp: 0.355 ± 0.017	1.208GlnTyr: 1.208 ± 0.036	0.0GlnXaa: 0.0 ± 0.0
Arg	2.388ArgAla: 2.388 ± 0.05	0.213ArgCys: 0.213 ± 0.015	2.207ArgAsp: 2.207 ± 0.051	3.291ArgGlu: 3.291 ± 0.055	2.118ArgPhe: 2.118 ± 0.046	2.235ArgGly: 2.235 ± 0.057	0.732ArgHis: 0.732 ± 0.026	3.321ArgIle: 3.321 ± 0.055	3.462ArgLys: 3.462 ± 0.057	3.778ArgLeu: 3.778 ± 0.063	0.985ArgMet: 0.985 ± 0.031	2.497ArgAsn: 2.497 ± 0.052	1.224ArgPro: 1.224 ± 0.037	1.39ArgGln: 1.39 ± 0.035	1.668ArgArg: 1.668 ± 0.047	2.366ArgSer: 2.366 ± 0.046	1.767ArgThr: 1.767 ± 0.042	2.277ArgVal: 2.277 ± 0.053	0.459ArgTrp: 0.459 ± 0.02	1.716ArgTyr: 1.716 ± 0.042	0.0ArgXaa: 0.0 ± 0.0
Ser	3.901SerAla: 3.901 ± 0.067	0.53SerCys: 0.53 ± 0.021	3.19SerAsp: 3.19 ± 0.058	4.842SerGlu: 4.842 ± 0.07	3.638SerPhe: 3.638 ± 0.057	4.769SerGly: 4.769 ± 0.062	1.095SerHis: 1.095 ± 0.035	4.681SerIle: 4.681 ± 0.071	4.13SerLys: 4.13 ± 0.07	6.553SerLeu: 6.553 ± 0.091	1.292SerMet: 1.292 ± 0.035	3.037SerAsn: 3.037 ± 0.055	2.275SerPro: 2.275 ± 0.041	2.092SerGln: 2.092 ± 0.05	2.753SerArg: 2.753 ± 0.057	4.023SerSer: 4.023 ± 0.072	3.058SerThr: 3.058 ± 0.053	3.884SerVal: 3.884 ± 0.057	0.729SerTrp: 0.729 ± 0.027	2.45SerTyr: 2.45 ± 0.052	0.0SerXaa: 0.0 ± 0.0
Thr	3.623ThrAla: 3.623 ± 0.068	0.285ThrCys: 0.285 ± 0.021	2.885ThrAsp: 2.885 ± 0.065	3.712ThrGlu: 3.712 ± 0.057	2.336ThrPhe: 2.336 ± 0.053	4.36ThrGly: 4.36 ± 0.061	0.945ThrHis: 0.945 ± 0.031	3.631ThrIle: 3.631 ± 0.063	3.072ThrLys: 3.072 ± 0.053	4.446ThrLeu: 4.446 ± 0.069	0.902ThrMet: 0.902 ± 0.029	2.543ThrAsn: 2.543 ± 0.048	2.335ThrPro: 2.335 ± 0.049	1.753ThrGln: 1.753 ± 0.041	2.056ThrArg: 2.056 ± 0.045	3.452ThrSer: 3.452 ± 0.061	2.863ThrThr: 2.863 ± 0.056	3.098ThrVal: 3.098 ± 0.058	0.528ThrTrp: 0.528 ± 0.022	2.162ThrTyr: 2.162 ± 0.051	0.0ThrXaa: 0.0 ± 0.0
Val	4.02ValAla: 4.02 ± 0.072	0.437ValCys: 0.437 ± 0.022	3.34ValAsp: 3.34 ± 0.058	4.382ValGlu: 4.382 ± 0.072	3.25ValPhe: 3.25 ± 0.058	3.689ValGly: 3.689 ± 0.072	1.045ValHis: 1.045 ± 0.034	4.854ValIle: 4.854 ± 0.065	4.22ValLys: 4.22 ± 0.067	5.94ValLeu: 5.94 ± 0.09	1.48ValMet: 1.48 ± 0.039	3.313ValAsn: 3.313 ± 0.053	2.209ValPro: 2.209 ± 0.045	1.865ValGln: 1.865 ± 0.042	2.127ValArg: 2.127 ± 0.043	4.058ValSer: 4.058 ± 0.067	3.059ValThr: 3.059 ± 0.064	3.921ValVal: 3.921 ± 0.076	0.551ValTrp: 0.551 ± 0.023	2.238ValTyr: 2.238 ± 0.045	0.0ValXaa: 0.0 ± 0.0
Trp	0.636TrpAla: 0.636 ± 0.025	0.073TrpCys: 0.073 ± 0.009	0.634TrpAsp: 0.634 ± 0.026	0.784TrpGlu: 0.784 ± 0.028	0.595TrpPhe: 0.595 ± 0.031	0.663TrpGly: 0.663 ± 0.025	0.238TrpHis: 0.238 ± 0.016	0.723TrpIle: 0.723 ± 0.023	0.825TrpLys: 0.825 ± 0.029	1.043TrpLeu: 1.043 ± 0.036	0.33TrpMet: 0.33 ± 0.017	0.608TrpAsn: 0.608 ± 0.023	0.304TrpPro: 0.304 ± 0.016	0.416TrpGln: 0.416 ± 0.02	0.463TrpArg: 0.463 ± 0.023	0.602TrpSer: 0.602 ± 0.025	0.504TrpThr: 0.504 ± 0.024	0.635TrpVal: 0.635 ± 0.027	0.153TrpTrp: 0.153 ± 0.011	0.442TrpTyr: 0.442 ± 0.021	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.294TyrAla: 2.294 ± 0.039	0.272TyrCys: 0.272 ± 0.015	2.183TyrAsp: 2.183 ± 0.048	2.598TyrGlu: 2.598 ± 0.057	2.373TyrPhe: 2.373 ± 0.051	2.665TyrGly: 2.665 ± 0.056	0.761TyrHis: 0.761 ± 0.027	2.519TyrIle: 2.519 ± 0.052	2.783TyrLys: 2.783 ± 0.051	3.966TyrLeu: 3.966 ± 0.074	0.7TyrMet: 0.7 ± 0.028	2.228TyrAsn: 2.228 ± 0.044	1.551TyrPro: 1.551 ± 0.036	1.495TyrGln: 1.495 ± 0.038	1.868TyrArg: 1.868 ± 0.046	2.657TyrSer: 2.657 ± 0.062	2.141TyrThr: 2.141 ± 0.048	2.002TyrVal: 2.002 ± 0.046	0.442TyrTrp: 0.442 ± 0.023	1.732TyrTyr: 1.732 ± 0.043	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3319 proteins (1093900 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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